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|id=CL:0000990
|id=CL:0000990
|name=conventional dendritic cell
|name=conventional dendritic cell
|namespace=cell
|namespace=efo
|def="Conventional dendritic cell is a dendritic cell that is CD11c-high." [GO_REF:0000031, GOC:amm, PMID:17850486]
|def="Conventional dendritic cell is a dendritic cell that is CD11c-high." [GO_REF:0000031, GOC:amm, PMID:17850486]
|xref=FMA:84191
|xref=FMA:84191
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|located_in=
|located_in=
|part_of=
|part_of=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.obo.owl
|is_obsolete=
|preceded_by=
}}
}}

Revision as of 17:39, 15 June 2012

Name:conventional dendritic cell
Namespace:efo
Definition:"Conventional dendritic cell is a dendritic cell that is CD11c-high." [GO_REF:0000031, GOC:amm, PMID:17850486]
Xrefs:
links:
FMA:84191
Synonyms: "cDC" EXACT []
"DC1" EXACT []
"dendritic reticular cell" EXACT []
"interdigitating cell" BROAD []
"type 1 DC" EXACT []
"veiled cell" BROAD []
Comments:Originally described in the dendritic cell ontology (DC_CL: 0000003)(PMID: 19243617) These cells are also CD20-negative, MHCII-positive.


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0000451(dendritic cell)



Children


is a:CL:0000453 (Langerhans cell),CL:0000840 (immature conventional dendritic cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

Human (Homo sapiens)

  • 10457-106G7 (squamous cell lung carcinoma cell line:LC-1F)
  • 10501-107C6 (squamous cell lung carcinoma cell line:RERF-LC-AI)
  • 11227-116C3 (Dendritic Cells - monocyte immature derived, donor1)
  • 11228-116C4 (Dendritic Cells - plasmacytoid, donor1)
  • 11308-117C3 (Dendritic Cells - monocyte immature derived, donor2)
  • 11384-118B7 (Dendritic Cells - monocyte immature derived, donor3)
  • 11901-125F2 (migratory langerhans cells, donor1)
  • 11902-125F3 (migratory langerhans cells, donor2)
  • 11903-125F4 (migratory langerhans cells, donor3)
  • 11904-125F5 (immature langerhans cells, donor1)

... further results Mouse (Mus musculus)

  • 10457-106G7 (squamous cell lung carcinoma cell line:LC-1F)
  • 10501-107C6 (squamous cell lung carcinoma cell line:RERF-LC-AI)
  • 11227-116C3 (Dendritic Cells - monocyte immature derived, donor1)
  • 11228-116C4 (Dendritic Cells - plasmacytoid, donor1)
  • 11308-117C3 (Dendritic Cells - monocyte immature derived, donor2)
  • 11384-118B7 (Dendritic Cells - monocyte immature derived, donor3)
  • 11901-125F2 (migratory langerhans cells, donor1)
  • 11902-125F3 (migratory langerhans cells, donor2)
  • 11903-125F4 (migratory langerhans cells, donor3)
  • 11904-125F5 (immature langerhans cells, donor1)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000990 (conventional dendritic cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
9.96e-174FFCP PHASE1:Hg19::chr15:101535004..101535045,+#_1ec5ca570a35492eb6cdf2322d4a86a3p@chr15:101535004..101535045, +
9.96e-174FFCP PHASE2:Hg19::chr15:101535004..101535045,+#_1ec5ca570a35492eb6cdf2322d4a86a3p@chr15:101535004..101535045, +
3.95e-152FFCP PHASE1:Hg19::chr16:57398251..57398254,+#_e123fca2244f1fe4dcf6882733320750p@chr16:57398251..57398254, +
3.95e-152FFCP PHASE1:Hg19::chr15:101534994..101535003,+#_e123fca2244f1fe4dcf6882733320750p@chr15:101534994..101535003, +
3.95e-152FFCP PHASE2:Hg19::chr15:101534994..101535003,+#_e123fca2244f1fe4dcf6882733320750p@chr15:101534994..101535003, +
3.95e-152FFCP PHASE2:Hg19::chr16:57398251..57398254,+#_e123fca2244f1fe4dcf6882733320750p@chr16:57398251..57398254, +
1.9e-139FFCP PHASE1:Hg19::chr13:75884283..75884317,-#_15103c23248e87474d89e8b81ac2a6eap@chr13:75884283..75884317, -
1.9e-139FFCP PHASE2:Hg19::chr13:75884283..75884317,-#_15103c23248e87474d89e8b81ac2a6eap@chr13:75884283..75884317, -
1.82e-133FFCP PHASE1:Hg19::chr16:10960104..10960115,+#_85cbdbc3b5a525b0da9259a6f318f606p4@AB463580
1.82e-133FFCP PHASE2:Hg19::chr16:10960104..10960115,+#_85cbdbc3b5a525b0da9259a6f318f606p4@AB463580
1.82e-133FFCP PHASE1:Hg19::chr15:101529373..101529387,+#_85cbdbc3b5a525b0da9259a6f318f606p@chr15:101529373..101529387, +
1.82e-133FFCP PHASE2:Hg19::chr15:101529373..101529387,+#_85cbdbc3b5a525b0da9259a6f318f606p@chr15:101529373..101529387, +
1.42e-130FFCP PHASE2:Hg19::chr3:119198717..119198735,+#_68339fa729e72aea9bd64b29de987e3dp@chr3:119198717..119198735, +
1.42e-130FFCP PHASE1:Hg19::chr3:119198717..119198735,+#_68339fa729e72aea9bd64b29de987e3dp@chr3:119198717..119198735, +
1.42e-130FFCP PHASE2:Hg19::chr2:61080954..61080964,+#_68339fa729e72aea9bd64b29de987e3dp@chr2:61080954..61080964, +
1.42e-130FFCP PHASE1:Hg19::chr18:59991691..59991708,+#_68339fa729e72aea9bd64b29de987e3dp@chr18:59991691..59991708, +
1.42e-130FFCP PHASE1:Hg19::chr2:61080954..61080964,+#_68339fa729e72aea9bd64b29de987e3dp@chr2:61080954..61080964, +
1.42e-130FFCP PHASE2:Hg19::chr18:59991691..59991708,+#_68339fa729e72aea9bd64b29de987e3dp@chr18:59991691..59991708, +
3.16e-127FFCP PHASE1:Hg19::chr16:10960091..10960099,+#_4a83ff0e022691943dea7d07fd2a6f49p3@AB463580
3.16e-127FFCP PHASE2:Hg19::chr16:10960091..10960099,+#_4a83ff0e022691943dea7d07fd2a6f49p3@AB463580
8.55e-119FFCP PHASE2:Hg19::chr16:57398441..57398460,+#_fa2d33d370f7adc04cbba2f873c97cd0p@chr16:57398441..57398460, +
8.55e-119FFCP PHASE1:Hg19::chr12:112513512..112513567,-#_fa2d33d370f7adc04cbba2f873c97cd0p@chr12:112513512..112513567, -
8.55e-119FFCP PHASE2:Hg19::chr12:112513512..112513567,-#_fa2d33d370f7adc04cbba2f873c97cd0p@chr12:112513512..112513567, -
8.55e-119FFCP PHASE1:Hg19::chr16:57398441..57398460,+#_fa2d33d370f7adc04cbba2f873c97cd0p@chr16:57398441..57398460, +
1.19e-116FFCP PHASE1:Hg19::chr13:75884320..75884362,-#_36a9804301a132c99964e91c825ab26ap@chr13:75884320..75884362, -
1.19e-116FFCP PHASE2:Hg19::chr13:75884320..75884362,-#_36a9804301a132c99964e91c825ab26ap@chr13:75884320..75884362, -
3.66e-112FFCP PHASE1:Hg19::chr16:57398263..57398266,+#_df8396f901a98c61a096e7333be276b4p@chr16:57398263..57398266, +
3.66e-112FFCP PHASE2:Hg19::chr16:57398263..57398266,+#_df8396f901a98c61a096e7333be276b4p@chr16:57398263..57398266, +
4.43e-112FFCP PHASE2:Hg19::chr16:57398271..57398274,+#_e447576d9d84e89de1a0f32c5f9951f6p@chr16:57398271..57398274, +
4.43e-112FFCP PHASE1:Hg19::chr16:57398271..57398274,+#_e447576d9d84e89de1a0f32c5f9951f6p@chr16:57398271..57398274, +
4.6e-109FFCP PHASE1:Hg19::chr16:10959804..10959811,+#_fb55be8ce958b459609dde489b645a52p5@AB463580
4.6e-109FFCP PHASE2:Hg19::chr16:10959804..10959811,+#_fb55be8ce958b459609dde489b645a52p5@AB463580
4.6e-109FFCP PHASE2:Hg19::chr3:119188705..119188718,+#_fb55be8ce958b459609dde489b645a52p@chr3:119188705..119188718, +
4.6e-109FFCP PHASE2:Hg19::chr6:32729529..32729536,-#_fb55be8ce958b459609dde489b645a52p3@M95729
4.6e-109FFCP PHASE1:Hg19::chr16:10959868..10959879,+#_fb55be8ce958b459609dde489b645a52p2@AB463580
4.6e-109FFCP PHASE1:Hg19::chr3:119188705..119188718,+#_fb55be8ce958b459609dde489b645a52p@chr3:119188705..119188718, +
4.6e-109FFCP PHASE2:Hg19::chr16:10959868..10959879,+#_fb55be8ce958b459609dde489b645a52p2@AB463580
4.6e-109FFCP PHASE1:Hg19::chr16:10885979..10885991,+#_fb55be8ce958b459609dde489b645a52p@chr16:10885979..10885991, +
4.6e-109FFCP PHASE2:Hg19::chr16:10885979..10885991,+#_fb55be8ce958b459609dde489b645a52p@chr16:10885979..10885991, +
4.6e-109FFCP PHASE2:Hg19::chr8:120974832..120974840,+#_fb55be8ce958b459609dde489b645a52p@chr8:120974832..120974840, +
4.6e-109FFCP PHASE1:Hg19::chr6:32729529..32729536,-#_fb55be8ce958b459609dde489b645a52p3@M95729
4.6e-109FFCP PHASE1:Hg19::chr16:10959880..10959887,+#_fb55be8ce958b459609dde489b645a52p6@AB463580
4.6e-109FFCP PHASE2:Hg19::chr16:10959880..10959887,+#_fb55be8ce958b459609dde489b645a52p6@AB463580
4.6e-109FFCP PHASE1:Hg19::chr8:120974832..120974840,+#_fb55be8ce958b459609dde489b645a52p@chr8:120974832..120974840, +
4.6e-109FFCP PHASE2:Hg19::chr1:201376546..201376550,+#_fb55be8ce958b459609dde489b645a52p@chr1:201376546..201376550, +
4.6e-109FFCP PHASE2:Hg19::chr3:52813932..52813943,+#_fb55be8ce958b459609dde489b645a52p11@ITIH1
4.6e-109FFCP PHASE2:Hg19::chr6:32726761..32726781,-#_fb55be8ce958b459609dde489b645a52p@chr6:32726761..32726781, -
4.6e-109FFCP PHASE1:Hg19::chr13:75884392..75884395,-#_fb55be8ce958b459609dde489b645a52p@chr13:75884392..75884395, -
4.6e-109FFCP PHASE2:Hg19::chr19:45487650..45487661,+#_fb55be8ce958b459609dde489b645a52p@chr19:45487650..45487661, +
4.6e-109FFCP PHASE1:Hg19::chr1:201376546..201376550,+#_fb55be8ce958b459609dde489b645a52p@chr1:201376546..201376550, +
4.6e-109FFCP PHASE2:Hg19::chr13:75884392..75884395,-#_fb55be8ce958b459609dde489b645a52p@chr13:75884392..75884395, -
4.6e-109FFCP PHASE1:Hg19::chr3:52813932..52813943,+#_fb55be8ce958b459609dde489b645a52p11@ITIH1
4.6e-109FFCP PHASE1:Hg19::chr6:32726761..32726781,-#_fb55be8ce958b459609dde489b645a52p@chr6:32726761..32726781, -
4.6e-109FFCP PHASE1:Hg19::chr19:45487650..45487661,+#_fb55be8ce958b459609dde489b645a52p@chr19:45487650..45487661, +
4.63e-108FFCP PHASE1:Hg19::chr16:57397882..57397931,-#_deaa52a840ab0488621f4487c79b07f3p1@CU693343
4.63e-108FFCP PHASE2:Hg19::chr16:57397882..57397931,-#_deaa52a840ab0488621f4487c79b07f3p1@CU693343
5.32e-108FFCP PHASE1:Hg19::chr16:57397593..57397602,+#_5765d0e25382654070edaaf3d71fd5d5p@chr16:57397593..57397602, +
5.32e-108FFCP PHASE2:Hg19::chr16:57397593..57397602,+#_5765d0e25382654070edaaf3d71fd5d5p@chr16:57397593..57397602, +
8.06e-108FFCP PHASE1:Hg19::chr16:57399022..57399038,+#_288c76ded6fffcb90068d95f631ef504p@chr16:57399022..57399038, +
8.06e-108FFCP PHASE2:Hg19::chr16:57399022..57399038,+#_288c76ded6fffcb90068d95f631ef504p@chr16:57399022..57399038, +
2.5e-107FFCP PHASE1:Hg19::chr16:57394436..57394449,+#_08bdc8533db89a66db1910012672fda4p@chr16:57394436..57394449, +
2.5e-107FFCP PHASE2:Hg19::chr16:57394436..57394449,+#_08bdc8533db89a66db1910012672fda4p@chr16:57394436..57394449, +
3.43e-107FFCP PHASE1:Hg19::chr16:57399043..57399070,+#_17a996806499e6b77e3b5da90b04696ap@chr16:57399043..57399070, +
3.43e-107FFCP PHASE2:Hg19::chr16:57399043..57399070,+#_17a996806499e6b77e3b5da90b04696ap@chr16:57399043..57399070, +
4.01e-107FFCP PHASE1:Hg19::chr16:57397927..57397934,+#_f2230b514217bbb6da2bcd16b4c46fccp@chr16:57397927..57397934, +
4.01e-107FFCP PHASE2:Hg19::chr16:57397927..57397934,+#_f2230b514217bbb6da2bcd16b4c46fccp@chr16:57397927..57397934, +
1.07e-100FFCP PHASE1:Hg19::chr16:57397735..57397758,-#_ddedf8fb13b0dced5a0cd05870d225dep3@CU693343
1.07e-100FFCP PHASE2:Hg19::chr16:57397735..57397758,-#_ddedf8fb13b0dced5a0cd05870d225dep3@CU693343
1.07e-100FFCP PHASE1:Hg19::chr16:57398987..57399006,+#_ddedf8fb13b0dced5a0cd05870d225dep@chr16:57398987..57399006, +
1.07e-100FFCP PHASE2:Hg19::chr16:57398987..57399006,+#_ddedf8fb13b0dced5a0cd05870d225dep@chr16:57398987..57399006, +
2.05e-99FFCP PHASE1:Hg19::chr6:341221..341236,-#_a50bda5d69e5a966bcaf02f73e8c661ap@chr6:341221..341236, -
2.05e-99FFCP PHASE2:Hg19::chr6:341221..341236,-#_a50bda5d69e5a966bcaf02f73e8c661ap@chr6:341221..341236, -
5.3e-94FFCP PHASE1:Hg19::chr16:57397561..57397572,+#_351ab349f116915f027d44936a03563dp@chr16:57397561..57397572, +
5.3e-94FFCP PHASE2:Hg19::chr16:57397561..57397572,+#_351ab349f116915f027d44936a03563dp@chr16:57397561..57397572, +
3.38e-91FFCP PHASE2:Hg19::chr1:159272441..159272452,+#_c97711d788e437703d252840386b669cp5@FCER1A
3.38e-91FFCP PHASE1:Hg19::chr13:75884255..75884262,-#_c97711d788e437703d252840386b669cp@chr13:75884255..75884262, -
3.38e-91FFCP PHASE1:Hg19::chr1:159272441..159272452,+#_c97711d788e437703d252840386b669cp5@FCER1A
3.38e-91FFCP PHASE2:Hg19::chr13:75884255..75884262,-#_c97711d788e437703d252840386b669cp@chr13:75884255..75884262, -
3.38e-91FFCP PHASE2:Hg19::chr2:173867941..173867955,+#_c97711d788e437703d252840386b669cp@chr2:173867941..173867955, +
3.38e-91FFCP PHASE1:Hg19::chr2:173867941..173867955,+#_c97711d788e437703d252840386b669cp@chr2:173867941..173867955, +
4.08e-91FFCP PHASE2:Hg19::chr1:159272420..159272431,+#_4931bad15025c2d942da1f334949e94dp3@FCER1A
4.08e-91FFCP PHASE1:Hg19::chr1:159272420..159272431,+#_4931bad15025c2d942da1f334949e94dp3@FCER1A
1.95e-88FFCP PHASE1:Hg19::chr16:57394384..57394402,+#_03bbe7b7c12b108f68ab5862178e8099p@chr16:57394384..57394402, +
1.95e-88FFCP PHASE2:Hg19::chr16:57394384..57394402,+#_03bbe7b7c12b108f68ab5862178e8099p@chr16:57394384..57394402, +
2.18e-88FFCP PHASE1:Hg19::chr16:57397581..57397590,+#_771db516e21cdad11eaef5a99091b482p@chr16:57397581..57397590, +
2.18e-88FFCP PHASE2:Hg19::chr16:57397581..57397590,+#_771db516e21cdad11eaef5a99091b482p@chr16:57397581..57397590, +
1.15e-87FFCP PHASE2:Hg19::chr1:157108764..157108776,-#_41301066f1da97992e82e42d97faec1dp7@ETV3
1.15e-87FFCP PHASE1:Hg19::chr1:157108764..157108776,-#_41301066f1da97992e82e42d97faec1dp7@ETV3
1.37e-87FFCP PHASE1:Hg19::chr12:112590221..112590232,+#_45bad81c2d27cef080fad815b8dcf782p@chr12:112590221..112590232, +
1.37e-87FFCP PHASE1:Hg19::chr16:10870586..10870591,-#_45bad81c2d27cef080fad815b8dcf782p@chr16:10870586..10870591, -
1.37e-87FFCP PHASE2:Hg19::chr16:10870586..10870591,-#_45bad81c2d27cef080fad815b8dcf782p@chr16:10870586..10870591, -
1.37e-87FFCP PHASE2:Hg19::chr14:65641128..65641129,-#_45bad81c2d27cef080fad815b8dcf782p@chr14:65641128..65641129, -
1.37e-87FFCP PHASE1:Hg19::chr4:16267477..16267486,-#_45bad81c2d27cef080fad815b8dcf782p@chr4:16267477..16267486, -
1.37e-87FFCP PHASE1:Hg19::chr3:52813951..52813958,+#_45bad81c2d27cef080fad815b8dcf782p13@ITIH1
1.37e-87FFCP PHASE1:Hg19::chr2:61081057..61081064,+#_45bad81c2d27cef080fad815b8dcf782p@chr2:61081057..61081064, +
1.37e-87FFCP PHASE1:Hg19::chr6:32729494..32729506,-#_45bad81c2d27cef080fad815b8dcf782p1@M95729
1.37e-87FFCP PHASE2:Hg19::chr2:71056842..71056868,+#_45bad81c2d27cef080fad815b8dcf782p@chr2:71056842..71056868, +
1.37e-87FFCP PHASE2:Hg19::chr3:52813997..52814015,+#_45bad81c2d27cef080fad815b8dcf782p9@ITIH1
1.37e-87FFCP PHASE2:Hg19::chr2:61081135..61081167,+#_45bad81c2d27cef080fad815b8dcf782p@chr2:61081135..61081167, +
1.37e-87FFCP PHASE1:Hg19::chr16:57399642..57399651,+#_45bad81c2d27cef080fad815b8dcf782p@chr16:57399642..57399651, +

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