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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0050716;positive regulation of interleukin-1 secretion;0.0132424415555956;15978!GO:0050706;regulation of interleukin-1 beta secretion;0.0132424415555956;15978!GO:0005133;interferon-gamma receptor binding;0.0132424415555956;15978!GO:0050702;interleukin-1 beta secretion;0.0132424415555956;15978!GO:0050718;positive regulation of interleukin-1 beta secretion;0.0132424415555956;15978!GO:0050704;regulation of interleukin-1 secretion;0.0132424415555956;15978!GO:0050701;interleukin-1 secretion;0.0132424415555956;15978!GO:0050715;positive regulation of cytokine secretion;0.0154473990081625;15978!GO:0031641;regulation of myelination;0.0154473990081625;15978!GO:0001781;neutrophil apoptosis;0.0154473990081625;15978!GO:0031642;negative regulation of myelination;0.0154473990081625;15978!GO:0006925;inflammatory cell apoptosis;0.0154473990081625;15978!GO:0045348;positive regulation of MHC class II biosynthetic process;0.0213857767070597;15978!GO:0045342;MHC class II biosynthetic process;0.021790176931256;15978!GO:0045346;regulation of MHC class II biosynthetic process;0.021790176931256;15978!GO:0001780;neutrophil homeostasis;0.021790176931256;15978!GO:0050714;positive regulation of protein secretion;0.021790176931256;15978!GO:0045084;positive regulation of interleukin-12 biosynthetic process;0.021790176931256;15978!GO:0031645;negative regulation of neurological process;0.021790176931256;15978!GO:0050707;regulation of cytokine secretion;0.021790176931256;15978!GO:0045080;positive regulation of chemokine biosynthetic process;0.021790176931256;15978!GO:0045410;positive regulation of interleukin-6 biosynthetic process;0.021790176931256;15978!GO:0050663;cytokine secretion;0.021790176931256;15978!GO:0048304;positive regulation of isotype switching to IgG isotypes;0.021790176931256;15978!GO:0045075;regulation of interleukin-12 biosynthetic process;0.021790176931256;15978!GO:0042090;interleukin-12 biosynthetic process;0.021790176931256;15978!GO:0045073;regulation of chemokine biosynthetic process;0.021790176931256;15978!GO:0050755;chemokine metabolic process;0.021790176931256;15978!GO:0042033;chemokine biosynthetic process;0.021790176931256;15978!GO:0045893;positive regulation of transcription, DNA-dependent;0.021790176931256;17355,15978!GO:0032602;chemokine production;0.021790176931256;15978!GO:0002262;myeloid cell homeostasis;0.021790176931256;15978!GO:0048302;regulation of isotype switching to IgG isotypes;0.021790176931256;15978!GO:0048291;isotype switching to IgG isotypes;0.021790176931256;15978!GO:0045830;positive regulation of isotype switching;0.0231488920247131;15978!GO:0045408;regulation of interleukin-6 biosynthetic process;0.0231488920247131;15978!GO:0051047;positive regulation of secretion;0.0243639173930027;15978!GO:0042226;interleukin-6 biosynthetic process;0.0243639173930027;15978!GO:0045941;positive regulation of transcription;0.024588616002105;17355,15978!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0249884364350635;17355,15978!GO:0030593;neutrophil chemotaxis;0.0252429620842483;15978!GO:0032615;interleukin-12 production;0.0252429620842483;15978!GO:0045191;regulation of isotype switching;0.0252429620842483;15978!GO:0030968;unfolded protein response;0.0252429620842483;15978!GO:0050708;regulation of protein secretion;0.0287877882763368;15978!GO:0031325;positive regulation of cellular metabolic process;0.031491687820385;17355,15978!GO:0032635;interleukin-6 production;0.031491687820385;15978!GO:0009893;positive regulation of metabolic process;0.0338567739381659;17355,15978!GO:0006984;ER-nuclear signaling pathway;0.0339727947245004;15978!GO:0030595;leukocyte chemotaxis;0.0351381559381551;15978!GO:0002208;somatic diversification of immunoglobulins during immune response;0.0366285591008257;15978!GO:0002204;somatic recombination of immunoglobulin genes during immune response;0.0366285591008257;15978!GO:0045190;isotype switching;0.0366285591008257;15978!GO:0002381;immunoglobulin production during immune response;0.037657011545733;15978!GO:0000082;G1/S transition of mitotic cell cycle;0.0399153947925838;56696!GO:0050871;positive regulation of B cell activation;0.0399153947925838;15978!GO:0031644;regulation of neurological process;0.0399153947925838;15978!GO:0001776;leukocyte homeostasis;0.0399153947925838;15978!GO:0016447;somatic recombination of immunoglobulin gene segments;0.0399153947925838;15978!GO:0042552;myelination;0.0399153947925838;15978!GO:0006402;mRNA catabolic process;0.0399153947925838;387609!GO:0048872;homeostasis of number of cells;0.0399153947925838;15978!GO:0007272;ensheathment of neurons;0.0399153947925838;15978!GO:0016444;somatic cell DNA recombination;0.0399153947925838;15978!GO:0008366;axon ensheathment;0.0399153947925838;15978!GO:0002562;somatic diversification of immune receptors via germline recombination within a single locus;0.0399153947925838;15978!GO:0009306;protein secretion;0.0399153947925838;15978!GO:0016445;somatic diversification of immunoglobulins;0.0399153947925838;15978!GO:0006986;response to unfolded protein;0.0399153947925838;15978!GO:0050900;leukocyte migration;0.0399153947925838;15978!GO:0051789;response to protein stimulus;0.0399153947925838;15978!GO:0002200;somatic diversification of immune receptors;0.0399153947925838;15978!GO:0006401;RNA catabolic process;0.0399153947925838;387609!GO:0042108;positive regulation of cytokine biosynthetic process;0.0399153947925838;15978!GO:0001608;nucleotide receptor activity, G-protein coupled;0.0421348562320759;56696!GO:0045028;purinergic nucleotide receptor activity, G-protein coupled;0.0421348562320759;56696!GO:0016502;nucleotide receptor activity;0.0421348562320759;56696!GO:0001614;purinergic nucleotide receptor activity;0.0421348562320759;56696!GO:0001508;regulation of action potential;0.0421348562320759;15978!GO:0005351;sugar:hydrogen ion symporter activity;0.0421348562320759;72144!GO:0050864;regulation of B cell activation;0.0421348562320759;15978!GO:0051119;sugar transmembrane transporter activity;0.0423108307625072;72144!GO:0005126;hematopoietin/interferon-class (D200-domain) cytokine receptor binding;0.0423108307625072;15978!GO:0002377;immunoglobulin production;0.0423108307625072;15978!GO:0015144;carbohydrate transmembrane transporter activity;0.0423108307625072;72144!GO:0002440;production of molecular mediator of immune response;0.042392315721844;15978!GO:0045727;positive regulation of translation;0.042392315721844;15978!GO:0051325;interphase;0.0424698555447445;56696!GO:0051329;interphase of mitotic cell cycle;0.0424698555447445;56696!GO:0031328;positive regulation of cellular biosynthetic process;0.0440345887227541;15978!GO:0006355;regulation of transcription, DNA-dependent;0.0469885842929266;17355,387609,15978!GO:0006351;transcription, DNA-dependent;0.0478399343710492;17355,387609,15978!GO:0032774;RNA biosynthetic process;0.0478399343710492;17355,387609,15978!GO:0009615;response to virus;0.0480042215885874;15978!GO:0042035;regulation of cytokine biosynthetic process;0.0484616437683431;15978!GO:0051046;regulation of secretion;0.0494937473468433;15978!GO:0045449;regulation of transcription;0.0494937473468433;17355,387609,15978!GO:0009891;positive regulation of biosynthetic process;0.0497763615691983;15978!}}
{{MCL_coexpression_mm9
|coexpression_dpi_cluster_scores_mean=0.0396986551919192,0.149714746110228,0.166351840940158,0.0907368856858658,0.111462990460243,0.062547194911189,0.0704520322075767,0.260673823207834,0.87885582697652,0.968527601481837,0.172756479804208,0.171067960349606,0.219060834193191,0.203114888274405,-0.00151910874079151,0.0540635149318099,0.0242421637662957,0.115740126156036,0.102667902991739,0.0915824837858381,0.0472368922369731,0.0158780503753909,0.0355138234465083,0.0294528342089963,0.038712208450445,0.0917430548793829,0.0573153947933157,0.0907271600479343,0.0597824564021127,0.0719609250316633,0.0489834753112744,0.00607416102245014,-0.00448638507286471,-0.0193570956829275,0.0184024816235049,-0.00203553948444425,0.0516227223381785,0.046433137384507,0.0360009569916934,0.0360520541031495,0.0191189818722848,0.0643636256150284,0.0486800615951405,0.00433036259312779,0.0177190287315917,0.000797836871775779,0.0165004849566631,0.0235580014881924,0.0125260459908882,0.0120456290573029,0.0238473332073066,0.00828213241202526,0.368851660808342,0.980030253996513,0.582559170027884,0.0219267832104592,-0.011541304325977,0.0155278164062167,0.00107297504266267,-0.00618531545628534,-0.00412800716289506,0.007799364868854,0.000378599199086,0.0385803131864135,0.0446298191721619,-0.00270580784766921,0.0150987714611279,0.000814988343401501,0.00278153336927898,0.00959782966282931,-0.00751395423581728,0.0242690102254153,0.0157221860119896,-0.00247965649361505,0.0126126046965161,-0.0193570956829275,0.0628130587479625,-0.00556921298900534,0.0131792231571188,-0.00237160606962406,0.0131853731407634,-0.00634963297916168,-0.00408099871436165,-0.00550759483014221,0.00867201053481594,0.000289658784482293,0.0134309766272184,0.00637859898469624,0.0619848770386552,-0.00397846685876893,0.170435055570053,0.0502091936537891,0.0578618058267122,0.00741962003421907,0.0220049388728393,0.0318198990641458,0.00775779362482014,-0.000494611863666664,-0.00502898435242779,-0.0193570956829275,0.0499812508432808,0.00625406692310452,0.0199279060883598,-0.0193570956829275,0.0718905024271675,0.0708602378072662,0.0925759734589548,0.0458458774764454,0.167955377132996,0.0586960705409419,0.00477084178328877,-0.0111119106604422,-0.00648246998328782,0.00134451031974002,0.0131294753299569,0.00634779274202989,0.0205144281336397,0.0131610269896021,0.0318985651074395,0.0196837389448691,0.0436470368296728,0.0608822267268582,-0.0193570956829275,0.0188398896764664,0.0313983876674617,0.0621711459750682,0.129996603495522,0.0243772428312534,0.0672759588942364,0.0170732095191604,0.0245997292181304,-0.00544788631565713,0.00857672920901509,0.0195355271860086,0.0230909835577263,0.0288065243566172,0.00335450266610382,0.0463594138917358,0.0429059764012773,0.0569421443876633,0.00882005732637701,-9.91218372616476e-05,0.0392778706728083,0.0134505229153755,0.0202407030614094,0.022976261830852,0.0281030396196619,0.034942584082359,0.00387429106823918,0.0134404842650947,0.0124980655878218,-0.00706089085013956,-0.0117466021168847,0.0213703222458435,0.0136385476330404,0.00642833723707842,-0.00285609920148657,0.0438938430828543,0.0649833316660484,0.0223052779567441,0.00564559919371645,0.0233957619093909,0.0244667818213847,0.00208097898273475,0.0260800939671847,-0.00638582584667597,0.0146646522434908,0.0162868881528422,0.00871879482878353,0.0113038717046034,0.0193953853290062,0.0332124696828442,0.0322603680852442,0.0082901252627737,0.0083443868672058,-0.0105130560423914,0.130262154684587,0.0192105276590701,0.00798119108688054,-0.0193570956829275,0.00844217539962734,0.00344007772536462,0.00661113540880671,-0.0139550030692074,0.0497911765269098,0.0113901269705836,0.0176620745559966,0.0490307176176485,0.0267740486465519,0.0204262846286007,0.0496794721396462,0.0479018505998017,-0.00858198942307959,-0.00593364910386493,-0.0193570956829275,0.00364310411078338,0.00180960584918949,0.0136226776056335,0.035867988845891,0.0283846358836697,0.0217506082116574,0.0454065795611981,-0.011303049104635,-0.00198142207484624,0.00187703358317157,-0.0015447673127743,0.0367608756817823,0.0149975975249264,0.000448326227088998,0.00258591178318226,0.0218193642983386,0.0480245010927134,0.0503064455548494,0.0273438219984319,0.0227665847838854,0.00729948922964036,0.0222896052695048,0.0172810806998248,0.0701212343469616,-0.0193570956829275,0.0111084688870679,0.00313857581168715,0.00371759279492918,-0.00143061897562734,0.0192183224183578,0.0471006203750558,0.033304664904659,0.0319470564384743,0.0344243875412042,0.0403921642718025,0.0190369293779178,0.0367496953994522,0.00916522137749086,0.0510787252102327,0.0178643761340945,0.0305857661244168,-0.0107188042213119,0.024673651352615,-0.00114188580542633,0.00728969203011975,-0.00234372911977953,0.0266729006874967,0.00386064148215785,-0.0193570956829275,0.00455413725604955,-0.0054403668404386,-0.00881296661317752,-0.011403630715792,0.0116422878962005,0.0200782344486598,0.00811705093905051,0.018620848146428,0.0267174402599407,0.0437871553058109,0.0330544211822839,0.0120395544669281,0.00350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|gostat_on_MCL_coexpression=GO:0050716;positive regulation of interleukin-1 secretion;0.0132424415555956;15978!GO:0050706;regulation of interleukin-1 beta secretion;0.0132424415555956;15978!GO:0005133;interferon-gamma receptor binding;0.0132424415555956;15978!GO:0050702;interleukin-1 beta secretion;0.0132424415555956;15978!GO:0050718;positive regulation of interleukin-1 beta secretion;0.0132424415555956;15978!GO:0050704;regulation of interleukin-1 secretion;0.0132424415555956;15978!GO:0050701;interleukin-1 secretion;0.0132424415555956;15978!GO:0050715;positive regulation of cytokine secretion;0.0154473990081625;15978!GO:0031641;regulation of myelination;0.0154473990081625;15978!GO:0001781;neutrophil apoptosis;0.0154473990081625;15978!GO:0031642;negative regulation of myelination;0.0154473990081625;15978!GO:0006925;inflammatory cell apoptosis;0.0154473990081625;15978!GO:0045348;positive regulation of MHC class II biosynthetic process;0.0213857767070597;15978!GO:0045342;MHC class II biosynthetic process;0.021790176931256;15978!GO:0045346;regulation of MHC class II biosynthetic process;0.021790176931256;15978!GO:0001780;neutrophil homeostasis;0.021790176931256;15978!GO:0050714;positive regulation of protein secretion;0.021790176931256;15978!GO:0045084;positive regulation of interleukin-12 biosynthetic process;0.021790176931256;15978!GO:0031645;negative regulation of neurological process;0.021790176931256;15978!GO:0050707;regulation of cytokine secretion;0.021790176931256;15978!GO:0045080;positive regulation of chemokine biosynthetic process;0.021790176931256;15978!GO:0045410;positive regulation of interleukin-6 biosynthetic process;0.021790176931256;15978!GO:0050663;cytokine secretion;0.021790176931256;15978!GO:0048304;positive regulation of isotype switching to IgG isotypes;0.021790176931256;15978!GO:0045075;regulation of interleukin-12 biosynthetic process;0.021790176931256;15978!GO:0042090;interleukin-12 biosynthetic process;0.021790176931256;15978!GO:0045073;regulation of chemokine biosynthetic process;0.021790176931256;15978!GO:0050755;chemokine metabolic process;0.021790176931256;15978!GO:0042033;chemokine biosynthetic process;0.021790176931256;15978!GO:0045893;positive regulation of transcription, DNA-dependent;0.021790176931256;17355,15978!GO:0032602;chemokine production;0.021790176931256;15978!GO:0002262;myeloid cell homeostasis;0.021790176931256;15978!GO:0048302;regulation of isotype switching to IgG isotypes;0.021790176931256;15978!GO:0048291;isotype switching to IgG isotypes;0.021790176931256;15978!GO:0045830;positive regulation of isotype switching;0.0231488920247131;15978!GO:0045408;regulation of interleukin-6 biosynthetic process;0.0231488920247131;15978!GO:0051047;positive regulation of secretion;0.0243639173930027;15978!GO:0042226;interleukin-6 biosynthetic process;0.0243639173930027;15978!GO:0045941;positive regulation of transcription;0.024588616002105;17355,15978!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0249884364350635;17355,15978!GO:0030593;neutrophil chemotaxis;0.0252429620842483;15978!GO:0032615;interleukin-12 production;0.0252429620842483;15978!GO:0045191;regulation of isotype switching;0.0252429620842483;15978!GO:0030968;unfolded protein response;0.0252429620842483;15978!GO:0050708;regulation of protein secretion;0.0287877882763368;15978!GO:0031325;positive regulation of cellular metabolic process;0.031491687820385;17355,15978!GO:0032635;interleukin-6 production;0.031491687820385;15978!GO:0009893;positive regulation of metabolic process;0.0338567739381659;17355,15978!GO:0006984;ER-nuclear signaling pathway;0.0339727947245004;15978!GO:0030595;leukocyte chemotaxis;0.0351381559381551;15978!GO:0002208;somatic diversification of immunoglobulins during immune response;0.0366285591008257;15978!GO:0002204;somatic recombination of immunoglobulin genes during immune response;0.0366285591008257;15978!GO:0045190;isotype switching;0.0366285591008257;15978!GO:0002381;immunoglobulin production during immune response;0.037657011545733;15978!GO:0000082;G1/S transition of mitotic cell cycle;0.0399153947925838;56696!GO:0050871;positive regulation of B cell activation;0.0399153947925838;15978!GO:0031644;regulation of neurological process;0.0399153947925838;15978!GO:0001776;leukocyte homeostasis;0.0399153947925838;15978!GO:0016447;somatic recombination of immunoglobulin gene segments;0.0399153947925838;15978!GO:0042552;myelination;0.0399153947925838;15978!GO:0006402;mRNA catabolic process;0.0399153947925838;387609!GO:0048872;homeostasis of number of cells;0.0399153947925838;15978!GO:0007272;ensheathment of neurons;0.0399153947925838;15978!GO:0016444;somatic cell DNA recombination;0.0399153947925838;15978!GO:0008366;axon ensheathment;0.0399153947925838;15978!GO:0002562;somatic diversification of immune receptors via germline recombination within a single locus;0.0399153947925838;15978!GO:0009306;protein secretion;0.0399153947925838;15978!GO:0016445;somatic diversification of immunoglobulins;0.0399153947925838;15978!GO:0006986;response to unfolded protein;0.0399153947925838;15978!GO:0050900;leukocyte migration;0.0399153947925838;15978!GO:0051789;response to protein stimulus;0.0399153947925838;15978!GO:0002200;somatic diversification of immune receptors;0.0399153947925838;15978!GO:0006401;RNA catabolic process;0.0399153947925838;387609!GO:0042108;positive regulation of cytokine biosynthetic process;0.0399153947925838;15978!GO:0001608;nucleotide receptor activity, G-protein coupled;0.0421348562320759;56696!GO:0045028;purinergic nucleotide receptor activity, G-protein coupled;0.0421348562320759;56696!GO:0016502;nucleotide receptor activity;0.0421348562320759;56696!GO:0001614;purinergic nucleotide receptor activity;0.0421348562320759;56696!GO:0001508;regulation of action potential;0.0421348562320759;15978!GO:0005351;sugar:hydrogen ion symporter activity;0.0421348562320759;72144!GO:0050864;regulation of B cell activation;0.0421348562320759;15978!GO:0051119;sugar transmembrane transporter activity;0.0423108307625072;72144!GO:0005126;hematopoietin/interferon-class (D200-domain) cytokine receptor binding;0.0423108307625072;15978!GO:0002377;immunoglobulin production;0.0423108307625072;15978!GO:0015144;carbohydrate transmembrane transporter activity;0.0423108307625072;72144!GO:0002440;production of molecular mediator of immune response;0.042392315721844;15978!GO:0045727;positive regulation of translation;0.042392315721844;15978!GO:0051325;interphase;0.0424698555447445;56696!GO:0051329;interphase of mitotic cell cycle;0.0424698555447445;56696!GO:0031328;positive regulation of cellular biosynthetic process;0.0440345887227541;15978!GO:0006355;regulation of transcription, DNA-dependent;0.0469885842929266;17355,387609,15978!GO:0006351;transcription, DNA-dependent;0.0478399343710492;17355,387609,15978!GO:0032774;RNA biosynthetic process;0.0478399343710492;17355,387609,15978!GO:0009615;response to virus;0.0480042215885874;15978!GO:0042035;regulation of cytokine biosynthetic process;0.0484616437683431;15978!GO:0051046;regulation of secretion;0.0494937473468433;15978!GO:0045449;regulation of transcription;0.0494937473468433;17355,387609,15978!GO:0009891;positive regulation of biosynthetic process;0.0497763615691983;15978!
}}

Revision as of 11:10, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr10:117878100..117878106,+p1@Ifng
Mm9::chr12:114099183..114099192,-p2@Gpr132
Mm9::chr15:57526415..57526425,+p7@Zhx2
Mm9::chr19:53608314..53608329,+p@chr19:53608314..53608329
+
Mm9::chr19:53608416..53608432,+p@chr19:53608416..53608432
+
Mm9::chr5:104182581..104182598,+p@chr5:104182581..104182598
+
Mm9::chr5:104182694..104182724,+p8@Aff1
Mm9::chr5:104182725..104182737,+p17@Aff1
Mm9::chr5:115938931..115938941,-p@chr5:115938931..115938941
-
Mm9::chr6:39327613..39327630,-p3@Slc37a3
Mm9::chr6:48687331..48687339,+p@chr6:48687331..48687339
+
Mm9::chr7:16531372..16531383,-p4@Gltscr2
Mm9::chr9:120019615..120019626,+p5@Slc25a38
Mm9::chrX:75691974..75691976,+p@chrX:75691974..75691976
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0050716positive regulation of interleukin-1 secretion0.0132424415555956
GO:0050706regulation of interleukin-1 beta secretion0.0132424415555956
GO:0005133interferon-gamma receptor binding0.0132424415555956
GO:0050702interleukin-1 beta secretion0.0132424415555956
GO:0050718positive regulation of interleukin-1 beta secretion0.0132424415555956
GO:0050704regulation of interleukin-1 secretion0.0132424415555956
GO:0050701interleukin-1 secretion0.0132424415555956
GO:0050715positive regulation of cytokine secretion0.0154473990081625
GO:0031641regulation of myelination0.0154473990081625
GO:0001781neutrophil apoptosis0.0154473990081625
GO:0031642negative regulation of myelination0.0154473990081625
GO:0006925inflammatory cell apoptosis0.0154473990081625
GO:0045348positive regulation of MHC class II biosynthetic process0.0213857767070597
GO:0045342MHC class II biosynthetic process0.021790176931256
GO:0045346regulation of MHC class II biosynthetic process0.021790176931256
GO:0001780neutrophil homeostasis0.021790176931256
GO:0050714positive regulation of protein secretion0.021790176931256
GO:0045084positive regulation of interleukin-12 biosynthetic process0.021790176931256
GO:0031645negative regulation of neurological process0.021790176931256
GO:0050707regulation of cytokine secretion0.021790176931256
GO:0045080positive regulation of chemokine biosynthetic process0.021790176931256
GO:0045410positive regulation of interleukin-6 biosynthetic process0.021790176931256
GO:0050663cytokine secretion0.021790176931256
GO:0048304positive regulation of isotype switching to IgG isotypes0.021790176931256
GO:0045075regulation of interleukin-12 biosynthetic process0.021790176931256
GO:0042090interleukin-12 biosynthetic process0.021790176931256
GO:0045073regulation of chemokine biosynthetic process0.021790176931256
GO:0050755chemokine metabolic process0.021790176931256
GO:0042033chemokine biosynthetic process0.021790176931256
GO:0045893positive regulation of transcription, DNA-dependent0.021790176931256
GO:0032602chemokine production0.021790176931256
GO:0002262myeloid cell homeostasis0.021790176931256
GO:0048302regulation of isotype switching to IgG isotypes0.021790176931256
GO:0048291isotype switching to IgG isotypes0.021790176931256
GO:0045830positive regulation of isotype switching0.0231488920247131
GO:0045408regulation of interleukin-6 biosynthetic process0.0231488920247131
GO:0051047positive regulation of secretion0.0243639173930027
GO:0042226interleukin-6 biosynthetic process0.0243639173930027
GO:0045941positive regulation of transcription0.024588616002105
GO:0045935positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0249884364350635
GO:0030593neutrophil chemotaxis0.0252429620842483
GO:0032615interleukin-12 production0.0252429620842483
GO:0045191regulation of isotype switching0.0252429620842483
GO:0030968unfolded protein response0.0252429620842483
GO:0050708regulation of protein secretion0.0287877882763368
GO:0031325positive regulation of cellular metabolic process0.031491687820385
GO:0032635interleukin-6 production0.031491687820385
GO:0009893positive regulation of metabolic process0.0338567739381659
GO:0006984ER-nuclear signaling pathway0.0339727947245004
GO:0030595leukocyte chemotaxis0.0351381559381551
GO:0002208somatic diversification of immunoglobulins during immune response0.0366285591008257
GO:0002204somatic recombination of immunoglobulin genes during immune response0.0366285591008257
GO:0045190isotype switching0.0366285591008257
GO:0002381immunoglobulin production during immune response0.037657011545733
GO:0000082G1/S transition of mitotic cell cycle0.0399153947925838
GO:0050871positive regulation of B cell activation0.0399153947925838
GO:0031644regulation of neurological process0.0399153947925838
GO:0001776leukocyte homeostasis0.0399153947925838
GO:0016447somatic recombination of immunoglobulin gene segments0.0399153947925838
GO:0042552myelination0.0399153947925838
GO:0006402mRNA catabolic process0.0399153947925838
GO:0048872homeostasis of number of cells0.0399153947925838
GO:0007272ensheathment of neurons0.0399153947925838
GO:0016444somatic cell DNA recombination0.0399153947925838
GO:0008366axon ensheathment0.0399153947925838
GO:0002562somatic diversification of immune receptors via germline recombination within a single locus0.0399153947925838
GO:0009306protein secretion0.0399153947925838
GO:0016445somatic diversification of immunoglobulins0.0399153947925838
GO:0006986response to unfolded protein0.0399153947925838
GO:0050900leukocyte migration0.0399153947925838
GO:0051789response to protein stimulus0.0399153947925838
GO:0002200somatic diversification of immune receptors0.0399153947925838
GO:0006401RNA catabolic process0.0399153947925838
GO:0042108positive regulation of cytokine biosynthetic process0.0399153947925838
GO:0001608nucleotide receptor activity, G-protein coupled0.0421348562320759
GO:0045028purinergic nucleotide receptor activity, G-protein coupled0.0421348562320759
GO:0016502nucleotide receptor activity0.0421348562320759
GO:0001614purinergic nucleotide receptor activity0.0421348562320759
GO:0001508regulation of action potential0.0421348562320759
GO:0005351sugar:hydrogen ion symporter activity0.0421348562320759
GO:0050864regulation of B cell activation0.0421348562320759
GO:0051119sugar transmembrane transporter activity0.0423108307625072
GO:0005126hematopoietin/interferon-class (D200-domain) cytokine receptor binding0.0423108307625072
GO:0002377immunoglobulin production0.0423108307625072
GO:0015144carbohydrate transmembrane transporter activity0.0423108307625072
GO:0002440production of molecular mediator of immune response0.042392315721844
GO:0045727positive regulation of translation0.042392315721844
GO:0051325interphase0.0424698555447445
GO:0051329interphase of mitotic cell cycle0.0424698555447445
GO:0031328positive regulation of cellular biosynthetic process0.0440345887227541
GO:0006355regulation of transcription, DNA-dependent0.0469885842929266
GO:0006351transcription, DNA-dependent0.0478399343710492
GO:0032774RNA biosynthetic process0.0478399343710492
GO:0009615response to virus0.0480042215885874
GO:0042035regulation of cytokine biosynthetic process0.0484616437683431
GO:0051046regulation of secretion0.0494937473468433
GO:0045449regulation of transcription0.0494937473468433
GO:0009891positive regulation of biosynthetic process0.0497763615691983



Relative expression of the co-expression cluster over median <br>Analyst:


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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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