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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0007548;sex differentiation;0.00119582923147353;16876,21416!GO:0003006;reproductive developmental process;0.00119582923147353;16876,21416!GO:0022414;reproductive process;0.00460555115778634;16876,21416!GO:0048619;embryonic hindgut morphogenesis;0.00597129392711993;21416!GO:0030538;embryonic genitalia morphogenesis;0.00597129392711993;21416!GO:0035112;genitalia morphogenesis;0.00597129392711993;21416!GO:0005667;transcription factor complex;0.00651360345025033;16876,21416!GO:0000003;reproduction;0.00651360345025033;16876,21416!GO:0007442;hindgut morphogenesis;0.00651360345025033;21416!GO:0048613;embryonic ectodermal gut morphogenesis;0.00651360345025033;21416!GO:0048611;embryonic ectodermal gut development;0.00651360345025033;21416!GO:0044451;nucleoplasm part;0.00674830909527291;16876,21416!GO:0048558;embryonic gut morphogenesis;0.00674830909527291;21416!GO:0005654;nucleoplasm;0.00674830909527291;16876,21416!GO:0048557;embryonic digestive tract morphogenesis;0.00674830909527291;21416!GO:0007439;ectodermal gut development;0.00674830909527291;21416!GO:0048567;ectodermal gut morphogenesis;0.00674830909527291;21416!GO:0048547;gut morphogenesis;0.00674830909527291;21416!GO:0048806;genitalia development;0.00674830909527291;21416!GO:0031981;nuclear lumen;0.00674830909527291;16876,21416!GO:0048566;embryonic gut development;0.00674830909527291;21416!GO:0048546;digestive tract morphogenesis;0.00674830909527291;21416!GO:0008013;beta-catenin binding;0.00674830909527291;21416!GO:0031974;membrane-enclosed lumen;0.00700277597950898;16876,21416!GO:0043233;organelle lumen;0.00700277597950898;16876,21416!GO:0008584;male gonad development;0.00767422299235825;16876!GO:0003700;transcription factor activity;0.00767422299235825;16876,21416!GO:0048565;gut development;0.00767422299235825;21416!GO:0048562;embryonic organ morphogenesis;0.00864381628664263;21416!GO:0046546;development of primary male sexual characteristics;0.00915096731892564;16876!GO:0044428;nuclear part;0.00998157778245865;16876,21416!GO:0046661;male sex differentiation;0.0100699331827434;16876!GO:0008585;female gonad development;0.0122628934130942;16876!GO:0046545;development of primary female sexual characteristics;0.0122628934130942;16876!GO:0046660;female sex differentiation;0.0122628934130942;16876!GO:0048568;embryonic organ development;0.0122628934130942;21416!GO:0048513;organ development;0.0154657633070033;16876,21416!GO:0008406;gonad development;0.0160071329758149;16876!GO:0048608;reproductive structure development;0.0162074394662785;16876!GO:0045137;development of primary sexual characteristics;0.0172906600818872;16876!GO:0021915;neural tube development;0.0188968127462959;21416!GO:0043234;protein complex;0.0188968127462959;16876,21416!GO:0048731;system development;0.0202777454796801;16876,21416!GO:0006355;regulation of transcription, DNA-dependent;0.0236243024285655;16876,21416!GO:0006351;transcription, DNA-dependent;0.0236243024285655;16876,21416!GO:0032774;RNA biosynthetic process;0.0236243024285655;16876,21416!GO:0003677;DNA binding;0.0237089321221221;16876,21416!GO:0045449;regulation of transcription;0.0238839324386906;16876,21416!GO:0048856;anatomical structure development;0.0238839324386906;16876,21416!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0238839324386906;16876,21416!GO:0006350;transcription;0.024032443516949;16876,21416!GO:0032991;macromolecular complex;0.0242324733088106;16876,21416!GO:0010468;regulation of gene expression;0.0247048942227348;16876,21416!GO:0031323;regulation of cellular metabolic process;0.0261887583221484;16876,21416!GO:0016055;Wnt receptor signaling pathway;0.0261887583221484;21416!GO:0007275;multicellular organismal development;0.0265189796586637;16876,21416!GO:0019222;regulation of metabolic process;0.0267678396391529;16876,21416!GO:0016070;RNA metabolic process;0.0277133635930366;16876,21416!GO:0044446;intracellular organelle part;0.0287082445500029;16876,21416!GO:0044422;organelle part;0.0287082445500029;16876,21416!GO:0010467;gene expression;0.0377243021012196;16876,21416!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0377243021012196;21416!GO:0048598;embryonic morphogenesis;0.0377243021012196;21416!GO:0003676;nucleic acid binding;0.0377243021012196;16876,21416!GO:0032502;developmental process;0.0395612071036099;16876,21416!GO:0043009;chordate embryonic development;0.0396857185934148;21416!GO:0009792;embryonic development ending in birth or egg hatching;0.0396857185934148;21416!GO:0045893;positive regulation of transcription, DNA-dependent;0.0406374537402066;21416!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0406374537402066;16876,21416!GO:0050794;regulation of cellular process;0.0460685674686323;16876,21416!GO:0045941;positive regulation of transcription;0.0469057581963048;21416!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0472341004380639;21416!}}
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0007548;sex differentiation;0.00119582923147353;16876,21416!GO:0003006;reproductive developmental process;0.00119582923147353;16876,21416!GO:0022414;reproductive process;0.00460555115778634;16876,21416!GO:0048619;embryonic hindgut morphogenesis;0.00597129392711993;21416!GO:0030538;embryonic genitalia morphogenesis;0.00597129392711993;21416!GO:0035112;genitalia morphogenesis;0.00597129392711993;21416!GO:0005667;transcription factor complex;0.00651360345025033;16876,21416!GO:0000003;reproduction;0.00651360345025033;16876,21416!GO:0007442;hindgut morphogenesis;0.00651360345025033;21416!GO:0048613;embryonic ectodermal gut morphogenesis;0.00651360345025033;21416!GO:0048611;embryonic ectodermal gut development;0.00651360345025033;21416!GO:0044451;nucleoplasm part;0.00674830909527291;16876,21416!GO:0048558;embryonic gut morphogenesis;0.00674830909527291;21416!GO:0005654;nucleoplasm;0.00674830909527291;16876,21416!GO:0048557;embryonic digestive tract morphogenesis;0.00674830909527291;21416!GO:0007439;ectodermal gut development;0.00674830909527291;21416!GO:0048567;ectodermal gut morphogenesis;0.00674830909527291;21416!GO:0048547;gut morphogenesis;0.00674830909527291;21416!GO:0048806;genitalia development;0.00674830909527291;21416!GO:0031981;nuclear lumen;0.00674830909527291;16876,21416!GO:0048566;embryonic gut development;0.00674830909527291;21416!GO:0048546;digestive tract morphogenesis;0.00674830909527291;21416!GO:0008013;beta-catenin binding;0.00674830909527291;21416!GO:0031974;membrane-enclosed lumen;0.00700277597950898;16876,21416!GO:0043233;organelle lumen;0.00700277597950898;16876,21416!GO:0008584;male gonad development;0.00767422299235825;16876!GO:0003700;transcription factor activity;0.00767422299235825;16876,21416!GO:0048565;gut development;0.00767422299235825;21416!GO:0048562;embryonic organ morphogenesis;0.00864381628664263;21416!GO:0046546;development of primary male sexual characteristics;0.00915096731892564;16876!GO:0044428;nuclear part;0.00998157778245865;16876,21416!GO:0046661;male sex differentiation;0.0100699331827434;16876!GO:0008585;female gonad development;0.0122628934130942;16876!GO:0046545;development of primary female sexual characteristics;0.0122628934130942;16876!GO:0046660;female sex differentiation;0.0122628934130942;16876!GO:0048568;embryonic organ development;0.0122628934130942;21416!GO:0048513;organ development;0.0154657633070033;16876,21416!GO:0008406;gonad development;0.0160071329758149;16876!GO:0048608;reproductive structure development;0.0162074394662785;16876!GO:0045137;development of primary sexual characteristics;0.0172906600818872;16876!GO:0021915;neural tube development;0.0188968127462959;21416!GO:0043234;protein complex;0.0188968127462959;16876,21416!GO:0048731;system development;0.0202777454796801;16876,21416!GO:0006355;regulation of transcription, DNA-dependent;0.0236243024285655;16876,21416!GO:0006351;transcription, DNA-dependent;0.0236243024285655;16876,21416!GO:0032774;RNA biosynthetic process;0.0236243024285655;16876,21416!GO:0003677;DNA binding;0.0237089321221221;16876,21416!GO:0045449;regulation of transcription;0.0238839324386906;16876,21416!GO:0048856;anatomical structure development;0.0238839324386906;16876,21416!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0238839324386906;16876,21416!GO:0006350;transcription;0.024032443516949;16876,21416!GO:0032991;macromolecular complex;0.0242324733088106;16876,21416!GO:0010468;regulation of gene expression;0.0247048942227348;16876,21416!GO:0031323;regulation of cellular metabolic process;0.0261887583221484;16876,21416!GO:0016055;Wnt receptor signaling pathway;0.0261887583221484;21416!GO:0007275;multicellular organismal development;0.0265189796586637;16876,21416!GO:0019222;regulation of metabolic process;0.0267678396391529;16876,21416!GO:0016070;RNA metabolic process;0.0277133635930366;16876,21416!GO:0044446;intracellular organelle part;0.0287082445500029;16876,21416!GO:0044422;organelle part;0.0287082445500029;16876,21416!GO:0010467;gene expression;0.0377243021012196;16876,21416!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0377243021012196;21416!GO:0048598;embryonic morphogenesis;0.0377243021012196;21416!GO:0003676;nucleic acid binding;0.0377243021012196;16876,21416!GO:0032502;developmental process;0.0395612071036099;16876,21416!GO:0043009;chordate embryonic development;0.0396857185934148;21416!GO:0009792;embryonic development ending in birth or egg hatching;0.0396857185934148;21416!GO:0045893;positive regulation of transcription, DNA-dependent;0.0406374537402066;21416!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0406374537402066;16876,21416!GO:0050794;regulation of cellular process;0.0460685674686323;16876,21416!GO:0045941;positive regulation of transcription;0.0469057581963048;21416!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0472341004380639;21416!
}}

Revision as of 11:27, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr19:55972403..55972421,+p22@Tcf7l2
Mm9::chr19:55972431..55972440,+p63@Tcf7l2
Mm9::chr19:55972441..55972456,+p18@Tcf7l2
Mm9::chr19:55985049..55985067,+p@chr19:55985049..55985067
+
Mm9::chr1:140743964..140743976,-p3@Lhx9


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0007548sex differentiation0.00119582923147353
GO:0003006reproductive developmental process0.00119582923147353
GO:0022414reproductive process0.00460555115778634
GO:0048619embryonic hindgut morphogenesis0.00597129392711993
GO:0030538embryonic genitalia morphogenesis0.00597129392711993
GO:0035112genitalia morphogenesis0.00597129392711993
GO:0005667transcription factor complex0.00651360345025033
GO:0000003reproduction0.00651360345025033
GO:0007442hindgut morphogenesis0.00651360345025033
GO:0048613embryonic ectodermal gut morphogenesis0.00651360345025033
GO:0048611embryonic ectodermal gut development0.00651360345025033
GO:0044451nucleoplasm part0.00674830909527291
GO:0048558embryonic gut morphogenesis0.00674830909527291
GO:0005654nucleoplasm0.00674830909527291
GO:0048557embryonic digestive tract morphogenesis0.00674830909527291
GO:0007439ectodermal gut development0.00674830909527291
GO:0048567ectodermal gut morphogenesis0.00674830909527291
GO:0048547gut morphogenesis0.00674830909527291
GO:0048806genitalia development0.00674830909527291
GO:0031981nuclear lumen0.00674830909527291
GO:0048566embryonic gut development0.00674830909527291
GO:0048546digestive tract morphogenesis0.00674830909527291
GO:0008013beta-catenin binding0.00674830909527291
GO:0031974membrane-enclosed lumen0.00700277597950898
GO:0043233organelle lumen0.00700277597950898
GO:0008584male gonad development0.00767422299235825
GO:0003700transcription factor activity0.00767422299235825
GO:0048565gut development0.00767422299235825
GO:0048562embryonic organ morphogenesis0.00864381628664263
GO:0046546development of primary male sexual characteristics0.00915096731892564
GO:0044428nuclear part0.00998157778245865
GO:0046661male sex differentiation0.0100699331827434
GO:0008585female gonad development0.0122628934130942
GO:0046545development of primary female sexual characteristics0.0122628934130942
GO:0046660female sex differentiation0.0122628934130942
GO:0048568embryonic organ development0.0122628934130942
GO:0048513organ development0.0154657633070033
GO:0008406gonad development0.0160071329758149
GO:0048608reproductive structure development0.0162074394662785
GO:0045137development of primary sexual characteristics0.0172906600818872
GO:0021915neural tube development0.0188968127462959
GO:0043234protein complex0.0188968127462959
GO:0048731system development0.0202777454796801
GO:0006355regulation of transcription, DNA-dependent0.0236243024285655
GO:0006351transcription, DNA-dependent0.0236243024285655
GO:0032774RNA biosynthetic process0.0236243024285655
GO:0003677DNA binding0.0237089321221221
GO:0045449regulation of transcription0.0238839324386906
GO:0048856anatomical structure development0.0238839324386906
GO:0019219regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0238839324386906
GO:0006350transcription0.024032443516949
GO:0032991macromolecular complex0.0242324733088106
GO:0010468regulation of gene expression0.0247048942227348
GO:0031323regulation of cellular metabolic process0.0261887583221484
GO:0016055Wnt receptor signaling pathway0.0261887583221484
GO:0007275multicellular organismal development0.0265189796586637
GO:0019222regulation of metabolic process0.0267678396391529
GO:0016070RNA metabolic process0.0277133635930366
GO:0044446intracellular organelle part0.0287082445500029
GO:0044422organelle part0.0287082445500029
GO:0010467gene expression0.0377243021012196
GO:0045944positive regulation of transcription from RNA polymerase II promoter0.0377243021012196
GO:0048598embryonic morphogenesis0.0377243021012196
GO:0003676nucleic acid binding0.0377243021012196
GO:0032502developmental process0.0395612071036099
GO:0043009chordate embryonic development0.0396857185934148
GO:0009792embryonic development ending in birth or egg hatching0.0396857185934148
GO:0045893positive regulation of transcription, DNA-dependent0.0406374537402066
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0406374537402066
GO:0050794regulation of cellular process0.0460685674686323
GO:0045941positive regulation of transcription0.0469057581963048
GO:0045935positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0472341004380639



Relative expression of the co-expression cluster over median <br>Analyst:


"{{{coexpression_dpi_cluster_scores_median}}}" is not a number.

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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