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MCL coexpression mm9:397: Difference between revisions

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{{MCL_coexpression_mm9
{{MCL_coexpression_mm9
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|coexpression_dpi_cluster_scores_median=0,0.743249447071025,0.744292387935012,0,0,0.454337428266695,0.523242497711745,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.04452104910867,1.09588261483083,0.700671165363817,0.790224904408165,0.742324098395807,0.0755555083173967,0,0.678465448440924,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.100004302423367,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0403878614760544,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
|gostat_on_MCL_coexpression=GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0165945545155982;27416,18671!GO:0043492;ATPase activity, coupled to movement of substances;0.0165945545155982;27416,18671!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0165945545155982;27416,18671!GO:0015399;primary active transmembrane transporter activity;0.0165945545155982;27416,18671!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0165945545155982;27416,18671!GO:0042910;xenobiotic transporter activity;0.0165945545155982;18671!GO:0008559;xenobiotic-transporting ATPase activity;0.0165945545155982;18671!GO:0015239;multidrug transporter activity;0.0193571315492903;18671!GO:0046581;intercellular canaliculus;0.0300962493678044;18671!GO:0042623;ATPase activity, coupled;0.0308035786832829;27416,18671!GO:0016887;ATPase activity;0.0354472679943566;27416,18671!GO:0042176;regulation of protein catabolic process;0.0354472679943566;66222!GO:0015893;drug transport;0.0358958214104973;18671!GO:0009894;regulation of catabolic process;0.0358958214104973;66222!GO:0015238;drug transporter activity;0.0360739735558713;18671!GO:0022804;active transmembrane transporter activity;0.0371635418739551;27416,18671!GO:0048029;monosaccharide binding;0.0476900747764418;83382!
|gostat_on_MCL_coexpression=GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0165945545155982;27416,18671!GO:0043492;ATPase activity, coupled to movement of substances;0.0165945545155982;27416,18671!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0165945545155982;27416,18671!GO:0015399;primary active transmembrane transporter activity;0.0165945545155982;27416,18671!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0165945545155982;27416,18671!GO:0042910;xenobiotic transporter activity;0.0165945545155982;18671!GO:0008559;xenobiotic-transporting ATPase activity;0.0165945545155982;18671!GO:0015239;multidrug transporter activity;0.0193571315492903;18671!GO:0046581;intercellular canaliculus;0.0300962493678044;18671!GO:0042623;ATPase activity, coupled;0.0308035786832829;27416,18671!GO:0016887;ATPase activity;0.0354472679943566;27416,18671!GO:0042176;regulation of protein catabolic process;0.0354472679943566;66222!GO:0015893;drug transport;0.0358958214104973;18671!GO:0009894;regulation of catabolic process;0.0358958214104973;66222!GO:0015238;drug transporter activity;0.0360739735558713;18671!GO:0022804;active transmembrane transporter activity;0.0371635418739551;27416,18671!GO:0048029;monosaccharide binding;0.0476900747764418;83382!
}}
}}

Revision as of 12:41, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr11:115993887..115993898,-p@chr11:115993887..115993898
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Mm9::chr11:115994191..115994226,-p@chr11:115994191..115994226
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Mm9::chr11:70323682..70323701,+p4@Tm4sf5
Mm9::chr13:32943045..32943055,-p1@Serpinb1a
Mm9::chr16:20364230..20364242,-p7@Abcc5
Mm9::chr18:65200347..65200364,-p@chr18:65200347..65200364
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Mm9::chr18:65200384..65200395,-p@chr18:65200384..65200395
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Mm9::chr19:5953618..5953632,+p@chr19:5953618..5953632
+
Mm9::chr3:158560571..158560574,+p@chr3:158560571..158560574
+
Mm9::chr4:117118403..117118419,+p1@ENSMUST00000136115
Mm9::chr4:117118428..117118440,+p2@ENSMUST00000136115
Mm9::chr5:8660633..8660652,+p@chr5:8660633..8660652
+
Mm9::chr6:82702729..82702733,-p@chr6:82702729..82702733
-
Mm9::chr6:86535959..86535964,-p@chr6:86535959..86535964
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Mm9::chr7:121860793..121860804,+p@chr7:121860793..121860804
+
Mm9::chr7:19117743..19117762,-p2@Psg25
Mm9::chr7:50606748..50606782,+p1@Siglec5
Mm9::chr7:52393029..52393077,-p@chr7:52393029..52393077
-
Mm9::chr8:8533654..8533663,+p@chr8:8533654..8533663
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0042626ATPase activity, coupled to transmembrane movement of substances0.0165945545155982
GO:0043492ATPase activity, coupled to movement of substances0.0165945545155982
GO:0016820hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances0.0165945545155982
GO:0015399primary active transmembrane transporter activity0.0165945545155982
GO:0015405P-P-bond-hydrolysis-driven transmembrane transporter activity0.0165945545155982
GO:0042910xenobiotic transporter activity0.0165945545155982
GO:0008559xenobiotic-transporting ATPase activity0.0165945545155982
GO:0015239multidrug transporter activity0.0193571315492903
GO:0046581intercellular canaliculus0.0300962493678044
GO:0042623ATPase activity, coupled0.0308035786832829
GO:0016887ATPase activity0.0354472679943566
GO:0042176regulation of protein catabolic process0.0354472679943566
GO:0015893drug transport0.0358958214104973
GO:0009894regulation of catabolic process0.0358958214104973
GO:0015238drug transporter activity0.0360739735558713
GO:0022804active transmembrane transporter activity0.0371635418739551
GO:0048029monosaccharide binding0.0476900747764418



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}