MCL coexpression mm9:2361

Phase1 CAGE Peaks

	Short description
Mm9::chr3:130412310..130412335,-	p1@Ostc
Mm9::chr3:88383524..88383649,+	p1@Ssr2
Mm9::chr4:137860750..137860807,+	p1@Ddost
Mm9::chr9:36575180..36575223,-	p1@Stt3a

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	3.8184626889391e-05
GO:0004576	oligosaccharyl transferase activity	3.8184626889391e-05
GO:0006486	protein amino acid glycosylation	0.00215630627038222
GO:0043413	biopolymer glycosylation	0.00215630627038222
GO:0009101	glycoprotein biosynthetic process	0.00215630627038222
GO:0005615	extracellular space	0.00215630627038222
GO:0009100	glycoprotein metabolic process	0.00215630627038222
GO:0044421	extracellular region part	0.00215630627038222
GO:0005783	endoplasmic reticulum	0.0022271787602198
GO:0016758	transferase activity, transferring hexosyl groups	0.00325864940663555
GO:0016757	transferase activity, transferring glycosyl groups	0.00790216886440309
GO:0045668	negative regulation of osteoblast differentiation	0.00790216886440309
GO:0018279	protein amino acid N-linked glycosylation via asparagine	0.00790216886440309
GO:0018196	peptidyl-asparagine modification	0.00790216886440309
GO:0005048	signal sequence binding	0.0132712798942626
GO:0045667	regulation of osteoblast differentiation	0.0165850098534568
GO:0030500	regulation of bone mineralization	0.0195069655714104
GO:0006487	protein amino acid N-linked glycosylation	0.0221006266309722
GO:0006613	cotranslational protein targeting to membrane	0.0221006266309722
GO:0030278	regulation of ossification	0.0252474800167617
GO:0030282	bone mineralization	0.0252474800167617
GO:0001649	osteoblast differentiation	0.025927158096923
GO:0006612	protein targeting to membrane	0.025927158096923
GO:0046850	regulation of bone remodeling	0.0266829806169947
GO:0009059	macromolecule biosynthetic process	0.0283868662340179

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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