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MCL coexpression mm9:3424: Difference between revisions

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{{MCL_coexpression_mm9
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0006926;virus-infected cell apoptosis;0.0253095210488937;12364!GO:0030968;unfolded protein response;0.0261331101426934;12364!GO:0030693;caspase activity;0.0261331101426934;12364!GO:0030500;regulation of bone mineralization;0.0261331101426934;12097!GO:0006984;ER-nuclear signaling pathway;0.0261331101426934;12364!GO:0030278;regulation of ossification;0.0261331101426934;12097!GO:0030282;bone mineralization;0.0261331101426934;12097!GO:0046850;regulation of bone remodeling;0.0261331101426934;12097!GO:0006986;response to unfolded protein;0.0261331101426934;12364!GO:0051789;response to protein stimulus;0.0261331101426934;12364!
|gostat_on_MCL_coexpression=GO:0006926;virus-infected cell apoptosis;0.0253095210488937;12364!GO:0030968;unfolded protein response;0.0261331101426934;12364!GO:0030693;caspase activity;0.0261331101426934;12364!GO:0030500;regulation of bone mineralization;0.0261331101426934;12097!GO:0006984;ER-nuclear signaling pathway;0.0261331101426934;12364!GO:0030278;regulation of ossification;0.0261331101426934;12097!GO:0030282;bone mineralization;0.0261331101426934;12097!GO:0046850;regulation of bone remodeling;0.0261331101426934;12097!GO:0006986;response to unfolded protein;0.0261331101426934;12364!GO:0051789;response to protein stimulus;0.0261331101426934;12364!
}}
}}

Revision as of 13:28, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr3:88182662..88182675,-p1@Bglap2
p3@Bglap-rs1
Mm9::chr9:5345414..5345435,+p2@Casp12
Mm9::chr9:5345450..5345505,+p1@Casp12


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0006926virus-infected cell apoptosis0.0253095210488937
GO:0030968unfolded protein response0.0261331101426934
GO:0030693caspase activity0.0261331101426934
GO:0030500regulation of bone mineralization0.0261331101426934
GO:0006984ER-nuclear signaling pathway0.0261331101426934
GO:0030278regulation of ossification0.0261331101426934
GO:0030282bone mineralization0.0261331101426934
GO:0046850regulation of bone remodeling0.0261331101426934
GO:0006986response to unfolded protein0.0261331101426934
GO:0051789response to protein stimulus0.0261331101426934



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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