MCL coexpression mm9:1653

Phase1 CAGE Peaks

	Short description
Mm9::chr13:6597624..6597628,-	p2@Pfkp
Mm9::chr15:102767247..102767265,+	p1@Hoxc12
Mm9::chr15:102767273..102767285,+	p2@Hoxc12
Mm9::chr2:74530108..74530131,+	p@chr2:74530108..74530131 +
Mm9::chr5:77527885..77527900,+	p@chr5:77527885..77527900 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0007389	pattern specification process	0.0152826463423504
GO:0005945	6-phosphofructokinase complex	0.0152826463423504
GO:0043234	protein complex	0.0152826463423504
GO:0003872	6-phosphofructokinase activity	0.0152826463423504
GO:0032991	macromolecular complex	0.0188334571863035
GO:0008443	phosphofructokinase activity	0.0188334571863035
GO:0005667	transcription factor complex	0.0188334571863035
GO:0043565	sequence-specific DNA binding	0.0188334571863035
GO:0009887	organ morphogenesis	0.0222044061746657
GO:0044451	nucleoplasm part	0.0222044061746657
GO:0005654	nucleoplasm	0.0222044061746657
GO:0031981	nuclear lumen	0.0286556891095618
GO:0031974	membrane-enclosed lumen	0.0295059949669166
GO:0043233	organelle lumen	0.0295059949669166
GO:0019200	carbohydrate kinase activity	0.0295059949669166
GO:0003700	transcription factor activity	0.0328018454917249
GO:0006096	glycolysis	0.0384670257346693
GO:0044428	nuclear part	0.0384670257346693
GO:0006007	glucose catabolic process	0.0384670257346693
GO:0046365	monosaccharide catabolic process	0.0384670257346693
GO:0019320	hexose catabolic process	0.0384670257346693
GO:0046164	alcohol catabolic process	0.0387905489148238
GO:0009653	anatomical structure morphogenesis	0.0418846667416595
GO:0044275	cellular carbohydrate catabolic process	0.0418846667416595
GO:0016052	carbohydrate catabolic process	0.0438502336937198

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
neuron of the ventral spinal cord	2.15e-08	3

Uber Anatomy

Ontology term	p-value	n
regional part of spinal cord	8.55e-13	5
gray matter of spinal cord	8.55e-13	5
spinal cord	1.44e-10	6
dorsal region element	1.44e-10	6
dorsum	1.44e-10	6
ventral horn of spinal cord	2.15e-08	3
forelimb	9.62e-08	7
pectoral appendage	9.62e-08	7
pectoral appendage bud	9.62e-08	7
forelimb bud	9.62e-08	7
forelimb/pectoral fin field	9.62e-08	7

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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