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|gostat_on_MCL_coexpression=GO:0008190;eukaryotic initiation factor 4E binding;0.00365236764732738;108112!GO:0031369;translation initiation factor binding;0.00365236764732738;108112!GO:0045947;negative regulation of translational initiation;0.00365236764732738;108112!GO:0006446;regulation of translational initiation;0.00949615588305119;108112!GO:0017148;negative regulation of translation;0.00949615588305119;108112!GO:0031327;negative regulation of cellular biosynthetic process;0.00949615588305119;108112!GO:0009890;negative regulation of biosynthetic process;0.0100179226898122;108112!GO:0006413;translational initiation;0.0120528132361804;108112!GO:0051248;negative regulation of protein metabolic process;0.015339944118775;108112!GO:0022618;protein-RNA complex assembly;0.015339944118775;108112!GO:0006417;regulation of translation;0.0253839551489253;108112!GO:0031326;regulation of cellular biosynthetic process;0.0253839551489253;108112!GO:0009889;regulation of biosynthetic process;0.0261284762462651;108112!GO:0022613;ribonucleoprotein complex biogenesis and assembly;0.0295841779433518;108112!GO:0051246;regulation of protein metabolic process;0.0336017823554119;108112!GO:0031324;negative regulation of cellular metabolic process;0.0399934257382348;108112!GO:0065003;macromolecular complex assembly;0.0401760441206012;108112!GO:0009892;negative regulation of metabolic process;0.0401760441206012;108112!GO:0022607;cellular component assembly;0.0427903704365829;108112!GO:0006412;translation;0.0466772585328439;108112!
|gostat_on_MCL_coexpression=GO:0008190;eukaryotic initiation factor 4E binding;0.00365236764732738;108112!GO:0031369;translation initiation factor binding;0.00365236764732738;108112!GO:0045947;negative regulation of translational initiation;0.00365236764732738;108112!GO:0006446;regulation of translational initiation;0.00949615588305119;108112!GO:0017148;negative regulation of translation;0.00949615588305119;108112!GO:0031327;negative regulation of cellular biosynthetic process;0.00949615588305119;108112!GO:0009890;negative regulation of biosynthetic process;0.0100179226898122;108112!GO:0006413;translational initiation;0.0120528132361804;108112!GO:0051248;negative regulation of protein metabolic process;0.015339944118775;108112!GO:0022618;protein-RNA complex assembly;0.015339944118775;108112!GO:0006417;regulation of translation;0.0253839551489253;108112!GO:0031326;regulation of cellular biosynthetic process;0.0253839551489253;108112!GO:0009889;regulation of biosynthetic process;0.0261284762462651;108112!GO:0022613;ribonucleoprotein complex biogenesis and assembly;0.0295841779433518;108112!GO:0051246;regulation of protein metabolic process;0.0336017823554119;108112!GO:0031324;negative regulation of cellular metabolic process;0.0399934257382348;108112!GO:0065003;macromolecular complex assembly;0.0401760441206012;108112!GO:0009892;negative regulation of metabolic process;0.0401760441206012;108112!GO:0022607;cellular component assembly;0.0427903704365829;108112!GO:0006412;translation;0.0466772585328439;108112!
|ontology_enrichment_celltype=CL:0000181!1.31e-09!5;CL:0000417!1.31e-09!5;CL:0000668!1.31e-09!5;CL:0000412!1.31e-09!5;CL:0000182!1.31e-09!5
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002107!2.22e-13!22;UBERON:0007499!2.22e-13!22;UBERON:0006925!2.22e-13!22;UBERON:0009497!2.22e-13!22;UBERON:0000015!2.22e-13!22;UBERON:0002423!2.22e-13!22;UBERON:0006235!2.22e-13!22;UBERON:0008835!2.22e-13!22;UBERON:0003894!2.22e-13!22;UBERON:0004161!2.22e-13!22;UBERON:0008836!2.22e-13!22;UBERON:0009854!1.26e-12!23;UBERON:0009856!1.26e-12!23;UBERON:0002365!2.64e-11!25;UBERON:0002330!2.64e-11!25
}}
}}

Revision as of 17:19, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr18:36823760..36823778,+p2@Eif4ebp3
Mm9::chr18:36823786..36823811,+p1@Eif4ebp3
Mm9::chr18:36824975..36825001,+p@chr18:36824975..36825001
+
Mm9::chr2:4816920..4816926,+p@chr2:4816920..4816926
+
Mm9::chr6:22293710..22293720,-p10@Fam3c


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0008190eukaryotic initiation factor 4E binding0.00365236764732738
GO:0031369translation initiation factor binding0.00365236764732738
GO:0045947negative regulation of translational initiation0.00365236764732738
GO:0006446regulation of translational initiation0.00949615588305119
GO:0017148negative regulation of translation0.00949615588305119
GO:0031327negative regulation of cellular biosynthetic process0.00949615588305119
GO:0009890negative regulation of biosynthetic process0.0100179226898122
GO:0006413translational initiation0.0120528132361804
GO:0051248negative regulation of protein metabolic process0.015339944118775
GO:0022618protein-RNA complex assembly0.015339944118775
GO:0006417regulation of translation0.0253839551489253
GO:0031326regulation of cellular biosynthetic process0.0253839551489253
GO:0009889regulation of biosynthetic process0.0261284762462651
GO:0022613ribonucleoprotein complex biogenesis and assembly0.0295841779433518
GO:0051246regulation of protein metabolic process0.0336017823554119
GO:0031324negative regulation of cellular metabolic process0.0399934257382348
GO:0065003macromolecular complex assembly0.0401760441206012
GO:0009892negative regulation of metabolic process0.0401760441206012
GO:0022607cellular component assembly0.0427903704365829
GO:0006412translation0.0466772585328439



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
metabolising cell1.31e-095
endopolyploid cell1.31e-095
parenchymal cell1.31e-095
polyploid cell1.31e-095
hepatocyte1.31e-095

Uber Anatomy
Ontology termp-valuen
liver2.22e-1322
epithelial sac2.22e-1322
digestive gland2.22e-1322
epithelium of foregut-midgut junction2.22e-1322
anatomical boundary2.22e-1322
hepatobiliary system2.22e-1322
foregut-midgut junction2.22e-1322
hepatic diverticulum2.22e-1322
liver primordium2.22e-1322
septum transversum2.22e-1322
liver bud2.22e-1322
digestive tract diverticulum1.26e-1223
sac1.26e-1223
exocrine gland2.64e-1125
exocrine system2.64e-1125


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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