MCL coexpression mm9:948

Phase1 CAGE Peaks

	Short description
Mm9::chr13:56803787..56803796,+	p@chr13:56803787..56803796 +
Mm9::chr19:45224323..45224368,+	p@chr19:45224323..45224368 +
Mm9::chr19:45224993..45225027,-	p@chr19:45224993..45225027 -
Mm9::chr19:45225149..45225186,+	p1@Tlx1
Mm9::chr19:45225276..45225304,+	p2@Tlx1
Mm9::chr5:42099208..42099253,-	p2@Rab28
Mm9::chr5:42155732..42155733,-	p3@Nkx3-2
Mm9::chr5:42155788..42155800,-	p1@Nkx3-2

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0048536	spleen development	5.59618874327475e-05
GO:0048534	hemopoietic or lymphoid organ development	0.0152916525558002
GO:0048645	organ formation	0.0152916525558002
GO:0002520	immune system development	0.0152916525558002
GO:0005667	transcription factor complex	0.0281699089806731
GO:0043565	sequence-specific DNA binding	0.0281699089806731
GO:0009887	organ morphogenesis	0.0281699089806731
GO:0044451	nucleoplasm part	0.0281699089806731
GO:0005654	nucleoplasm	0.0281699089806731
GO:0048706	embryonic skeletal development	0.0281699089806731
GO:0048535	lymph node development	0.0281699089806731
GO:0031981	nuclear lumen	0.0322382065132781
GO:0048705	skeletal morphogenesis	0.0322382065132781
GO:0002376	immune system process	0.032536455815222
GO:0031974	membrane-enclosed lumen	0.032536455815222
GO:0043233	organelle lumen	0.032536455815222
GO:0003700	transcription factor activity	0.0368476139110079

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
viscus	3.90e-19	19
stomach	2.12e-14	16
food storage organ	2.12e-14	16
spleen	3.26e-13	6
cavity lining	3.26e-13	6
serous membrane	3.26e-13	6
gastrointestinal system mesentery	3.26e-13	6
stomach region	3.26e-13	6
mesentery	3.26e-13	6
gastrointestinal system serosa	3.26e-13	6
mesentery of stomach	3.26e-13	6
gut mesentery	3.26e-13	6
dorsal mesentery	3.26e-13	6
dorsal mesogastrium	3.26e-13	6
peritoneal cavity	3.26e-13	6
spleen primordium	3.26e-13	6
body cavity	1.44e-10	37
body cavity or lining	1.44e-10	37
body cavity precursor	3.52e-10	38
pancreas	7.99e-10	12
anatomical cavity	8.21e-10	39
intraembryonic coelom	1.63e-07	10

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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