Coexpression cluster:C115

Full id: C115_pituitary_Neural_caudate_putamen_amygdala_medulla_hippocampus

Phase1 CAGE Peaks

Hg19::chr10:106423509..106423521,+	p@chr10:106423509..106423521 +
Hg19::chr10:123959529..123959547,+	p@chr10:123959529..123959547 +
Hg19::chr10:18579999..18580012,-	p@chr10:18579999..18580012 -
Hg19::chr10:18580030..18580043,-	p@chr10:18580030..18580043 -
Hg19::chr10:18580125..18580134,+	p@chr10:18580125..18580134 +
Hg19::chr10:18580138..18580153,+	p@chr10:18580138..18580153 +
Hg19::chr11:111601666..111601697,-	p@chr11:111601666..111601697 -
Hg19::chr11:68419276..68419303,-	p@chr11:68419276..68419303 -
Hg19::chr11:9088284..9088330,-	p4@SCUBE2
Hg19::chr12:113697781..113697814,+	p7@TPCN1
Hg19::chr12:80603044..80603046,+	p1@OTOGL
Hg19::chr12:89881337..89881342,-	p@chr12:89881337..89881342 -
Hg19::chr12:89881348..89881356,-	p@chr12:89881348..89881356 -
Hg19::chr13:40924577..40924587,-	p2@ENST00000400432
Hg19::chr13:40924605..40924623,-	p1@ENST00000400432
Hg19::chr13:51617751..51617754,+	p@chr13:51617751..51617754 +
Hg19::chr14:62584108..62584133,+	p1@FLJ43390
Hg19::chr14:62584173..62584178,+	p2@ENST00000334389
Hg19::chr15:24157554..24157578,+	p@chr15:24157554..24157578 +
Hg19::chr15:33445488..33445523,-	p@chr15:33445488..33445523 -
Hg19::chr15:33445536..33445552,-	p@chr15:33445536..33445552 -
Hg19::chr15:48681810..48681835,-	p@chr15:48681810..48681835 -
Hg19::chr15:62352961..62352973,-	p8@VPS13C
Hg19::chr15:89147906..89147920,+	p@chr15:89147906..89147920 +
Hg19::chr16:21049173..21049231,-	p@chr16:21049173..21049231 -
Hg19::chr17:18021982..18021985,+	p3@MYO15A
Hg19::chr17:191188..191219,-	p@chr17:191188..191219 -
Hg19::chr17:191225..191238,-	p@chr17:191225..191238 -
Hg19::chr17:61995906..61995914,-	p6@AB591020
Hg19::chr17:61995979..61995990,-	p2@AB591020
Hg19::chr17:61995995..61996002,-	p3@AB591020
Hg19::chr17:61996018..61996019,-	p5@AB591020
Hg19::chr17:61996155..61996158,-	p5@GH1
Hg19::chr17:61996160..61996176,-	p3@GH1
Hg19::chr17:61996252..61996253,-	p2@GH1 p3@CSHL1
Hg19::chr17:61996393..61996421,-	p4@CSHL1 p4@GH1
Hg19::chr18:21824830..21824832,-	p@chr18:21824830..21824832 -
Hg19::chr19:14095105..14095108,-	p@chr19:14095105..14095108 -
Hg19::chr19:14946017..14946050,-	p3@OR7A5
Hg19::chr19:2608406..2608413,-	p@chr19:2608406..2608413 -
Hg19::chr19:46801484..46801498,+	p9@HIF3A
Hg19::chr19:4770772..4770775,+	p1@MIR7-3
Hg19::chr19:47793168..47793181,+	p@chr19:47793168..47793181 +
Hg19::chr1:109656644..109656670,+	p4@KIAA1324
Hg19::chr1:114483276..114483289,+	p@chr1:114483276..114483289 +
Hg19::chr1:159116850..159116858,-	p10@AIM2
Hg19::chr1:159116897..159116903,-	p12@AIM2
Hg19::chr1:168250110..168250120,+	p2@TBX19
Hg19::chr1:168250194..168250197,+	p3@TBX19
Hg19::chr1:206942410..206942414,-	p@chr1:206942410..206942414 -
Hg19::chr1:240286421..240286436,+	p@chr1:240286421..240286436 +
Hg19::chr1:43400328..43400332,+	p@chr1:43400328..43400332 +
Hg19::chr1:7709325..7709329,+	p@chr1:7709325..7709329 +
Hg19::chr20:20505922..20505946,-	p@chr20:20505922..20505946 -
Hg19::chr20:31667446..31667451,+	p1@BPIFB4
Hg19::chr20:33451327..33451358,-	p4@GGT7
Hg19::chr20:57415768..57415803,+	p@chr20:57415768..57415803 +
Hg19::chr20:58401707..58401714,+	p@chr20:58401707..58401714 +
Hg19::chr20:58401898..58401905,+	p@chr20:58401898..58401905 +
Hg19::chr22:45015998..45016005,-	p@chr22:45015998..45016005 -
Hg19::chr2:130941446..130941486,-	p1@CU676019
Hg19::chr2:1714065..1714071,+	p@chr2:1714065..1714071 +
Hg19::chr2:187287127..187287143,-	p@chr2:187287127..187287143 -
Hg19::chr2:211830430..211830435,+	p@chr2:211830430..211830435 +
Hg19::chr2:211830446..211830457,+	p@chr2:211830446..211830457 +
Hg19::chr2:241080084..241080093,-	p5@OTOS
Hg19::chr2:25383828..25383855,-	p4@POMC
Hg19::chr2:25383910..25383918,-	p17@POMC
Hg19::chr2:25383947..25383959,+	p@chr2:25383947..25383959 +
Hg19::chr2:25391399..25391417,-	p8@POMC
Hg19::chr2:25391425..25391439,-	p10@POMC
Hg19::chr2:25391442..25391456,-	p1@POMC
Hg19::chr2:25391468..25391485,-	p5@POMC
Hg19::chr2:25391507..25391519,-	p9@POMC
Hg19::chr2:25391657..25391666,-	p14@POMC
Hg19::chr2:25391815..25391821,-	p13@POMC
Hg19::chr2:45161466..45161475,+	p@chr2:45161466..45161475 +
Hg19::chr2:58113353..58113375,-	p@chr2:58113353..58113375 -
Hg19::chr2:58113386..58113399,-	p@chr2:58113386..58113399 -
Hg19::chr2:58113402..58113415,-	p@chr2:58113402..58113415 -
Hg19::chr2:58113422..58113431,-	p@chr2:58113422..58113431 -
Hg19::chr2:70312872..70312889,-	p23@PCBP1-AS1
Hg19::chr2:70312899..70312908,-	p44@PCBP1-AS1
Hg19::chr2:7497646..7497649,+	p@chr2:7497646..7497649 +
Hg19::chr2:98962912..98962924,+	p2@CNGA3
Hg19::chr3:108321623..108321685,+	p4@DZIP3
Hg19::chr3:114477881..114477914,-	p17@ZBTB20
Hg19::chr3:118521917..118521922,-	p@chr3:118521917..118521922 -
Hg19::chr3:130248877..130248886,+	p@chr3:130248877..130248886 +
Hg19::chr3:130248915..130248922,+	p@chr3:130248915..130248922 +
Hg19::chr3:130248948..130248959,+	p@chr3:130248948..130248959 +
Hg19::chr3:133115455..133115457,+	p@chr3:133115455..133115457 +
Hg19::chr3:154042775..154042780,-	p8@DHX36
Hg19::chr3:185324217..185324224,+	p1@ENST00000455173
Hg19::chr3:24206603..24206613,-	p17@THRB
Hg19::chr3:24206934..24206942,-	p24@THRB
Hg19::chr3:4774755..4774765,+	p@chr3:4774755..4774765 +
Hg19::chr3:58572679..58572682,-	p30@FAM107A
Hg19::chr3:58572689..58572703,-	p6@FAM107A
Hg19::chr3:58572720..58572733,-	p11@FAM107A
Hg19::chr3:58572734..58572746,-	p8@FAM107A
Hg19::chr3:58572760..58572774,-	p9@FAM107A
Hg19::chr3:79817089..79817094,-	p27@ROBO1
Hg19::chr3:87325636..87325643,-	p2@POU1F1
Hg19::chr3:87325728..87325739,-	p1@POU1F1
Hg19::chr4:108815402..108815408,+	p13@SGMS2
Hg19::chr4:1352813..1352818,-	p@chr4:1352813..1352818 -
Hg19::chr4:6635531..6635534,+	p@chr4:6635531..6635534 +
Hg19::chr4:70518941..70518967,-	p1@UGT2A1 p1@UGT2A2
Hg19::chr4:76359403..76359419,-	p1@ENST00000510744
Hg19::chr4:8103287..8103292,+	p@chr4:8103287..8103292 +
Hg19::chr5:132668491..132668494,+	p@chr5:132668491..132668494 +
Hg19::chr5:134509776..134509792,+	p@chr5:134509776..134509792 +
Hg19::chr5:134509799..134509814,+	p@chr5:134509799..134509814 +
Hg19::chr5:158737729..158737738,-	p@chr5:158737729..158737738 -
Hg19::chr5:158737824..158737862,+	p1@ENST00000521472
Hg19::chr5:165553564..165553568,-	p@chr5:165553564..165553568 -
Hg19::chr5:77409743..77409752,-	p6@AP3B1
Hg19::chr6:12717892..12717903,+	p23@PHACTR1
Hg19::chr6:139155017..139155049,-	p@chr6:139155017..139155049 -
Hg19::chr6:163149056..163149101,+	p2@PACRG
Hg19::chr6:168333280..168333294,+	p9@MLLT4
Hg19::chr6:22287516..22287522,-	p@chr6:22287516..22287522 -
Hg19::chr6:22287527..22287538,-	p@chr6:22287527..22287538 -
Hg19::chr6:22287619..22287636,-	p@chr6:22287619..22287636 -
Hg19::chr6:22287669..22287676,-	p@chr6:22287669..22287676 -
Hg19::chr6:22287695..22287700,-	p@chr6:22287695..22287700 -
Hg19::chr6:22297257..22297272,-	p1@PRL
Hg19::chr6:82727317..82727327,+	p@chr6:82727317..82727327 +
Hg19::chr6:88805080..88805083,-	p@chr6:88805080..88805083 -
Hg19::chr7:103549700..103549706,-	p@chr7:103549700..103549706 -
Hg19::chr7:150644605..150644616,-	p@chr7:150644605..150644616 -
Hg19::chr7:31003560..31003576,+	p5@GHRHR
Hg19::chr7:31003580..31003589,+	p6@GHRHR
Hg19::chr7:31006649..31006651,+	p@chr7:31006649..31006651 +
Hg19::chr7:31009189..31009197,+	p11@GHRHR
Hg19::chr7:31010569..31010576,+	p9@GHRHR
Hg19::chr7:31010582..31010601,+	p4@GHRHR
Hg19::chr7:31016265..31016282,+	p@chr7:31016265..31016282 +
Hg19::chr7:95114742..95114776,+	p4@ASB4
Hg19::chr8:1066886..1066919,+	p@chr8:1066886..1066919 +
Hg19::chr8:107844170..107844179,+	p@chr8:107844170..107844179 +
Hg19::chr8:130017368..130017390,+	p@chr8:130017368..130017390 +
Hg19::chr9:135964996..135965001,+	p@chr9:135964996..135965001 +
Hg19::chr9:135965121..135965124,+	p@chr9:135965121..135965124 +
Hg19::chr9:547212..547233,+	p28@KANK1
Hg19::chr9:75568126..75568136,-	p13@ALDH1A1
Hg19::chr9:75568163..75568197,-	p8@ALDH1A1
Hg19::chrX:111923145..111923173,-	p1@LHFPL1
Hg19::chrX:130215591..130215605,+	p@chrX:130215591..130215605 +
Hg19::chrX:130215610..130215625,+	p@chrX:130215610..130215625 +
Hg19::chrX:130215640..130215656,+	p@chrX:130215640..130215656 +
Hg19::chrX:130423240..130423288,-	p1@IGSF1
Hg19::chrX:130423386..130423397,-	p6@IGSF1
Hg19::chrX:147887590..147887594,+	p@chrX:147887590..147887594 +
Hg19::chrX:150345054..150345060,+	p1@GPR50
Hg19::chrX:24169518..24169522,+	p8@ZFX
Hg19::chrX:38147077..38147085,-	p@chrX:38147077..38147085 -
Hg19::chrX:38183144..38183165,-	p@chrX:38183144..38183165 -
Hg19::chrX:9528518..9528536,+	p@chrX:9528518..9528536 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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p.value	FDR	nGenes	nPathway	Name
2.57139298499459e-05	0.0162769175950157	5	272	Neuroactive ligand-receptor interaction (KEGG):04080

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0050954	sensory perception of mechanical stimulus	0.0393796071001252
GO:0007605	sensory perception of sound	0.0393796071001252
GO:0005515	protein binding	0.0393796071001252
GO:0032501	multicellular organismal process	0.0445827919264483
GO:0048187	inhibin beta-B binding	0.0445827919264483
GO:0031593	polyubiquitin binding	0.0445827919264483
GO:0005179	hormone activity	0.0445827919264483
GO:0007600	sensory perception	0.0445827919264483
GO:0051138	positive regulation of NK T cell differentiation	0.0445827919264483
GO:0033188	sphingomyelin synthase activity	0.0445827919264483
GO:0047493	ceramide cholinephosphotransferase activity	0.0445827919264483
GO:0048007	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	0.0445827919264483
GO:0001865	NK T cell differentiation	0.0445827919264483
GO:0051136	regulation of NK T cell differentiation	0.0445827919264483
GO:0048186	inhibin beta-A binding	0.0445827919264483
GO:0005148	prolactin receptor binding	0.0445827919264483
GO:0048856	anatomical structure development	0.0445827919264483
GO:0003008	system process	0.0445827919264483
GO:0002475	antigen processing and presentation via MHC class Ib	0.0445827919264483
GO:0021984	adenohypophysis development	0.0445827919264483
GO:0001758	retinal dehydrogenase activity	0.0445827919264483
GO:0008046	axon guidance receptor activity	0.0445827919264483
GO:0006686	sphingomyelin biosynthetic process	0.0445827919264483
GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib	0.0445827919264483
GO:0003712	transcription cofactor activity	0.0445827919264483

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
pituitary gland	3.29e-195	2
gland of diencephalon	1.55e-98	4
neuroendocrine gland	1.55e-98	4
diencephalon	4.76e-57	7
future diencephalon	4.76e-57	7
endocrine gland	1.42e-12	35
regional part of forebrain	1.07e-10	41
forebrain	1.07e-10	41
anterior neural tube	1.07e-10	41
future forebrain	1.07e-10	41
endocrine system	4.55e-10	45
regional part of nervous system	1.34e-08	53
regional part of brain	1.34e-08	53
neural tube	3.28e-08	56
neural rod	3.28e-08	56
future spinal cord	3.28e-08	56
neural keel	3.28e-08	56
gland	5.66e-08	59
pre-chordal neural plate	1.20e-07	61
brain	6.59e-07	68
future brain	6.59e-07	68

Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}

ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

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No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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