MCL coexpression mm9:849

Phase1 CAGE Peaks

	Short description
Mm9::chr5:140290185..140290233,-	p4@Tmem184a
Mm9::chr6:124668826..124668853,-	p2@ENSMUST00000143765
Mm9::chr6:124668855..124668875,-	p1@ENSMUST00000143765
Mm9::chr7:30066635..30066707,-	p3@Spint2
Mm9::chr7:30066957..30066992,-	p2@Spint2
Mm9::chr7:30066998..30067009,-	p4@Spint2
Mm9::chr7:31758487..31758499,-	p5@Lsr
Mm9::chr7:31758805..31758835,+	p2@Fam187b
Mm9::chr8:73905344..73905381,-	p2@Nr2f6

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0043153	entrainment of circadian clock by photoperiod	0.0124910973538596
GO:0009648	photoperiodism	0.0124910973538596
GO:0009649	entrainment of circadian clock	0.0166506905596417
GO:0042953	lipoprotein transport	0.0166506905596417
GO:0050965	detection of temperature stimulus during sensory perception of pain	0.0166506905596417
GO:0050961	detection of temperature stimulus during sensory perception	0.0166506905596417
GO:0016048	detection of temperature stimulus	0.0181584189925705
GO:0042627	chylomicron	0.0181584189925705
GO:0050951	sensory perception of temperature stimulus	0.0181584189925705
GO:0030169	low-density lipoprotein binding	0.0181584189925705
GO:0030228	lipoprotein receptor activity	0.0181584189925705
GO:0008034	lipoprotein binding	0.027037364610579
GO:0001889	liver development	0.0402895678942441
GO:0019233	sensory perception of pain	0.0445231456193193
GO:0007623	circadian rhythm	0.048187877866731

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
endoderm-derived structure	1.10e-15	118
endoderm	1.10e-15	118
presumptive endoderm	1.10e-15	118
intestine	2.32e-15	31
digestive system	3.20e-15	116
digestive tract	3.20e-15	116
primitive gut	3.20e-15	116
subdivision of digestive tract	3.52e-14	114
gastrointestinal system	1.33e-13	47
mucosa	1.21e-09	15
immaterial anatomical entity	1.53e-09	79
anatomical space	3.22e-09	57
intestinal mucosa	1.78e-08	13
anatomical wall	1.78e-08	13
wall of intestine	1.78e-08	13
gastrointestinal system mucosa	1.78e-08	13
trunk region element	3.71e-08	79
pancreas	2.09e-07	12

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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