Novel motif:25

name:	motif25_GATCCN

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0001970	positive regulation of activation of membrane attack complex	1.115581e-9
GO:0097045	phosphatidylserine exposure on blood platelet	1.313264e-9
GO:0035356	cellular triglyceride homeostasis	6.096997e-9
GO:0008588	release of cytoplasmic sequestered NF-kappaB	5.142040e-8
GO:0010890	positive regulation of sequestering of triglyceride	1.833119e-7
GO:0010625	positive regulation of Schwann cell proliferation	2.460071e-7
GO:0009301	snRNA transcription	2.574034e-7
GO:0048484	enteric nervous system development	4.480352e-7
GO:0050747	positive regulation of lipoprotein metabolic process	5.027062e-7
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	5.412328e-7
GO:0034389	lipid particle organization	5.949302e-7
GO:0001798	positive regulation of type IIa hypersensitivity	8.087111e-7
GO:0060708	spongiotrophoblast differentiation	1.074893e-6
GO:0045109	intermediate filament organization	1.377131e-6
GO:0060707	trophoblast giant cell differentiation	1.909842e-6
GO:0002502	peptide antigen assembly with MHC class I protein complex	1.932774e-6
GO:0032226	positive regulation of synaptic transmission, dopaminergic	4.931712e-6
GO:0035729	cellular response to hepatocyte growth factor stimulus	5.250283e-6
GO:0060020	Bergmann glial cell differentiation	5.760407e-6
GO:0051580	regulation of neurotransmitter uptake	6.200182e-6
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	7.885320e-6
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	7.885320e-6
GO:0010288	response to lead ion	8.496502e-6
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	9.051443e-6
GO:0010954	positive regulation of protein processing	9.629537e-6
GO:0009649	entrainment of circadian clock	1.011433e-5
GO:0031167	rRNA methylation	1.021264e-5
GO:0000725	recombinational repair	1.140259e-5
GO:0000154	rRNA modification	1.161686e-5
GO:0060706	cell differentiation involved in embryonic placenta development	1.235732e-5
GO:0006297	nucleotide-excision repair, DNA gap filling	1.264651e-5
GO:0007620	copulation	1.339233e-5
GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation	1.568774e-5
GO:0006563	L-serine metabolic process	1.843574e-5
GO:0046501	protoporphyrinogen IX metabolic process	1.956990e-5
GO:0046314	phosphocreatine biosynthetic process	1.960869e-5
GO:0042396	phosphagen biosynthetic process	2.004545e-5
GO:0048483	autonomic nervous system development	2.281693e-5
GO:0072553	terminal button organization	2.811332e-5
GO:0042168	heme metabolic process	2.882225e-5
GO:0008215	spermine metabolic process	3.353181e-5
GO:0051208	sequestering of calcium ion	3.398550e-5
GO:0003360	brainstem development	3.829434e-5
GO:0090130	tissue migration	4.399014e-5
GO:0000724	double-strand break repair via homologous recombination	4.460373e-5
GO:0046208	spermine catabolic process	4.548112e-5
GO:0060465	pharynx development	4.844469e-5
GO:0034227	tRNA thio-modification	5.080102e-5
GO:0002098	tRNA wobble uridine modification	5.080102e-5
GO:0010310	regulation of hydrogen peroxide metabolic process	5.186965e-5
GO:0006783	heme biosynthetic process	5.340893e-5
GO:0015891	siderophore transport	5.580445e-5
GO:0010002	cardioblast differentiation	6.104147e-5
GO:0008078	mesodermal cell migration	6.721755e-5
GO:0008272	sulfate transport	6.926240e-5
GO:0009313	oligosaccharide catabolic process	7.751754e-5
GO:0033693	neurofilament bundle assembly	7.862379e-5
GO:0021591	ventricular system development	9.460636e-5
GO:0021670	lateral ventricle development	9.552739e-5
GO:0090394	negative regulation of excitatory postsynaptic membrane potential	1.167828e-4
GO:0010624	regulation of Schwann cell proliferation	1.193543e-4
GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity	1.201646e-4
GO:0071028	nuclear mRNA surveillance	1.369689e-4
GO:0006184	GTP catabolic process	1.462650e-4
GO:0048880	sensory system development	1.569418e-4
GO:0060712	spongiotrophoblast layer development	1.582186e-4
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	1.694917e-4
GO:0050830	defense response to Gram-positive bacterium	1.762787e-4
GO:0006596	polyamine biosynthetic process	1.845487e-4
GO:0006427	histidyl-tRNA aminoacylation	1.992960e-4
GO:0042946	glucoside transport	2.142134e-4
GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin	2.149075e-4
GO:0006598	polyamine catabolic process	2.185756e-4
GO:0048773	erythrophore differentiation	2.243966e-4
GO:0034021	response to silicon dioxide	2.243966e-4
GO:0003069	vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure	2.243966e-4
GO:0001315	age-dependent response to reactive oxygen species	2.243966e-4
GO:0046039	GTP metabolic process	2.370210e-4
GO:0030851	granulocyte differentiation	2.436002e-4
GO:0001941	postsynaptic membrane organization	2.610760e-4
GO:0009071	serine family amino acid catabolic process	2.726130e-4
GO:0097105	presynaptic membrane assembly	2.769311e-4
GO:0009199	ribonucleoside triphosphate metabolic process	2.786976e-4
GO:0032695	negative regulation of interleukin-12 production	2.935661e-4
GO:0009205	purine ribonucleoside triphosphate metabolic process	3.146608e-4
GO:0051497	negative regulation of stress fiber assembly	3.307555e-4
GO:0045110	intermediate filament bundle assembly	3.367569e-4
GO:0032091	negative regulation of protein binding	3.501051e-4
GO:0009144	purine nucleoside triphosphate metabolic process	3.507393e-4
GO:0045576	mast cell activation	3.654312e-4
GO:0021678	third ventricle development	3.751575e-4
GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway	3.954664e-4
GO:0010889	regulation of sequestering of triglyceride	4.138725e-4
GO:0060789	hair follicle placode formation	4.237018e-4
GO:0045837	negative regulation of membrane potential	4.294991e-4
GO:0060600	dichotomous subdivision of an epithelial terminal unit	4.297760e-4
GO:0006422	aspartyl-tRNA aminoacylation	4.341068e-4
GO:0010923	negative regulation of phosphatase activity	4.633143e-4
GO:0048841	regulation of axon extension involved in axon guidance	4.776233e-4
GO:0006473	protein acetylation	4.883540e-4
GO:0046950	cellular ketone body metabolic process	4.915404e-4
GO:0035814	negative regulation of renal sodium excretion	4.972705e-4
GO:0045792	negative regulation of cell size	5.142027e-4
GO:0006097	glyoxylate cycle	5.196043e-4
GO:0060252	positive regulation of glial cell proliferation	5.488928e-4
GO:0044258	intestinal lipid catabolic process	5.827178e-4
GO:0018350	protein esterification	5.827178e-4
GO:0015911	plasma membrane long-chain fatty acid transport	5.842582e-4
GO:0009141	nucleoside triphosphate metabolic process	5.910894e-4
GO:0010631	epithelial cell migration	6.157725e-4
GO:0001881	receptor recycling	6.325681e-4
GO:0042376	phylloquinone catabolic process	6.423137e-4
GO:0006518	peptide metabolic process	6.508766e-4
GO:0090398	cellular senescence	6.734158e-4
GO:0002885	positive regulation of hypersensitivity	6.881779e-4
GO:0090045	positive regulation of deacetylase activity	6.963705e-4
GO:0002553	histamine secretion by mast cell	7.018586e-4
GO:2000119	negative regulation of sodium-dependent phosphate transport	7.203287e-4
GO:0033159	negative regulation of protein import into nucleus, translocation	7.206643e-4
GO:0030186	melatonin metabolic process	7.206643e-4
GO:0006749	glutathione metabolic process	7.212858e-4
GO:0006844	acyl carnitine transport	7.237638e-4
GO:0010045	response to nickel ion	7.298552e-4
GO:0009107	lipoate biosynthetic process	7.298552e-4
GO:0042866	pyruvate biosynthetic process	7.499658e-4
GO:0002883	regulation of hypersensitivity	7.587108e-4
GO:0050764	regulation of phagocytosis	7.598501e-4
GO:0060158	activation of phospholipase C activity by dopamine receptor signaling pathway	7.829474e-4
GO:0021592	fourth ventricle development	8.406402e-4
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	8.406402e-4
GO:0046952	ketone body catabolic process	8.624777e-4
GO:0051481	reduction of cytosolic calcium ion concentration	8.637529e-4
GO:0022601	menstrual cycle phase	8.827838e-4
GO:0046466	membrane lipid catabolic process	8.869368e-4
GO:0032383	regulation of intracellular cholesterol transport	9.031734e-4
GO:0019883	antigen processing and presentation of endogenous antigen	9.493988e-4
GO:0006458	'de novo' protein folding	9.549996e-4
GO:0018393	internal peptidyl-lysine acetylation	9.662912e-4
GO:0060371	regulation of atrial cardiomyocyte membrane depolarization	1.014502e-3
GO:2000009	negative regulation of protein localization at cell surface	1.014502e-3
GO:0050754	positive regulation of fractalkine biosynthetic process	1.014502e-3
GO:0050725	positive regulation of interleukin-1 beta biosynthetic process	1.014502e-3
GO:0071636	positive regulation of transforming growth factor beta production	1.053416e-3
GO:0071025	RNA surveillance	1.075918e-3
GO:0018394	peptidyl-lysine acetylation	1.091318e-3
GO:0051882	mitochondrial depolarization	1.091655e-3
GO:0043308	eosinophil degranulation	1.095519e-3
GO:0051881	regulation of mitochondrial membrane potential	1.104237e-3
GO:0010226	response to lithium ion	1.139927e-3
GO:0046521	sphingoid catabolic process	1.147413e-3
GO:0007509	mesoderm migration involved in gastrulation	1.176257e-3
GO:0051289	protein homotetramerization	1.199599e-3
GO:0001569	patterning of blood vessels	1.207750e-3
GO:0071899	negative regulation of estrogen receptor binding	1.223678e-3
GO:0060023	soft palate development	1.224969e-3
GO:0006778	porphyrin-containing compound metabolic process	1.227092e-3
GO:0019377	glycolipid catabolic process	1.273636e-3
GO:0006475	internal protein amino acid acetylation	1.293865e-3
GO:0070613	regulation of protein processing	1.363763e-3
GO:0018198	peptidyl-cysteine modification	1.368894e-3
GO:0006260	DNA replication	1.393968e-3
GO:0014002	astrocyte development	1.403712e-3
GO:0010823	negative regulation of mitochondrion organization	1.441802e-3
GO:0018119	peptidyl-cysteine S-nitrosylation	1.464371e-3
GO:0032287	peripheral nervous system myelin maintenance	1.490886e-3
GO:0032042	mitochondrial DNA metabolic process	1.512718e-3
GO:0000416	positive regulation of histone H3-K36 methylation	1.525186e-3
GO:0051084	'de novo' posttranslational protein folding	1.569767e-3
GO:0071044	histone mRNA catabolic process	1.581846e-3
GO:0043249	erythrocyte maturation	1.591549e-3
GO:0016255	attachment of GPI anchor to protein	1.612294e-3
GO:0045625	regulation of T-helper 1 cell differentiation	1.627059e-3
GO:0007249	I-kappaB kinase/NF-kappaB cascade	1.657015e-3
GO:0048012	hepatocyte growth factor receptor signaling pathway	1.726699e-3
GO:0048485	sympathetic nervous system development	1.740316e-3
GO:0006565	L-serine catabolic process	1.755055e-3
GO:0006779	porphyrin-containing compound biosynthetic process	1.822903e-3
GO:0050916	sensory perception of sweet taste	1.883198e-3
GO:0051100	negative regulation of binding	1.910576e-3
GO:0016073	snRNA metabolic process	1.919786e-3
GO:0009635	response to herbicide	1.932586e-3
GO:0048339	paraxial mesoderm development	1.941650e-3
GO:0015936	coenzyme A metabolic process	1.945293e-3
GO:0061028	establishment of endothelial barrier	1.980214e-3
GO:0007431	salivary gland development	1.989646e-3
GO:0045103	intermediate filament-based process	2.064120e-3
GO:0032225	regulation of synaptic transmission, dopaminergic	2.097291e-3
GO:0042696	menarche	2.120264e-3
GO:0030157	pancreatic juice secretion	2.138723e-3
GO:0060301	positive regulation of cytokine activity	2.173342e-3
GO:0006275	regulation of DNA replication	2.182025e-3
GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein	2.190245e-3
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	2.208202e-3
GO:0035621	ER to Golgi ceramide transport	2.208202e-3
GO:0009589	detection of UV	2.208202e-3
GO:0045081	negative regulation of interleukin-10 biosynthetic process	2.251451e-3
GO:0043000	Golgi to plasma membrane CFTR protein transport	2.269322e-3
GO:0060299	negative regulation of sarcomere organization	2.269322e-3
GO:0033292	T-tubule organization	2.269322e-3
GO:0006689	ganglioside catabolic process	2.269470e-3
GO:0030149	sphingolipid catabolic process	2.277516e-3
GO:0021636	trigeminal nerve morphogenesis	2.304634e-3
GO:0097090	presynaptic membrane organization	2.363529e-3
GO:0009142	nucleoside triphosphate biosynthetic process	2.374354e-3
GO:0070527	platelet aggregation	2.393355e-3
GO:0006261	DNA-dependent DNA replication	2.455571e-3
GO:0021782	glial cell development	2.488534e-3
GO:0042510	regulation of tyrosine phosphorylation of Stat1 protein	2.497917e-3
GO:0006399	tRNA metabolic process	2.520367e-3
GO:0009629	response to gravity	2.529304e-3
GO:0032929	negative regulation of superoxide anion generation	2.549359e-3
GO:0010693	negative regulation of alkaline phosphatase activity	2.572812e-3
GO:0002922	positive regulation of humoral immune response	2.619502e-3
GO:0007413	axonal fasciculation	2.628004e-3
GO:0035305	negative regulation of dephosphorylation	2.675223e-3
GO:0043084	penile erection	2.681484e-3
GO:0050917	sensory perception of umami taste	2.686857e-3
GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	2.692714e-3
GO:0033013	tetrapyrrole metabolic process	2.720943e-3
GO:0030866	cortical actin cytoskeleton organization	2.741536e-3
GO:0090232	positive regulation of spindle checkpoint	2.754477e-3
GO:0046323	glucose import	2.794730e-3
GO:0051156	glucose 6-phosphate metabolic process	2.812712e-3
GO:0043330	response to exogenous dsRNA	2.815903e-3
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	2.818819e-3
GO:0031053	primary miRNA processing	2.826757e-3
GO:0007435	salivary gland morphogenesis	2.845964e-3
GO:0016052	carbohydrate catabolic process	2.869047e-3
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	2.881054e-3
GO:0010735	positive regulation of transcription via serum response element binding	2.894776e-3
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	2.895460e-3
GO:0006264	mitochondrial DNA replication	2.895460e-3
GO:0050935	iridophore differentiation	2.904025e-3
GO:0048937	lateral line nerve glial cell development	2.904025e-3
GO:0007009	plasma membrane organization	2.951514e-3
GO:0003334	keratinocyte development	2.971059e-3
GO:0032465	regulation of cytokinesis	2.971233e-3
GO:0046329	negative regulation of JNK cascade	3.004711e-3
GO:0008049	male courtship behavior	3.015222e-3
GO:0010734	negative regulation of protein glutathionylation	3.015222e-3
GO:0046113	nucleobase catabolic process	3.053819e-3
GO:0048242	epinephrine secretion	3.109470e-3
GO:0061196	fungiform papilla development	3.124567e-3
GO:0030194	positive regulation of blood coagulation	3.147241e-3
GO:0070120	ciliary neurotrophic factor-mediated signaling pathway	3.151842e-3
GO:0002825	regulation of T-helper 1 type immune response	3.300941e-3
GO:0009201	ribonucleoside triphosphate biosynthetic process	3.305259e-3
GO:0060338	regulation of type I interferon-mediated signaling pathway	3.343848e-3
GO:0006595	polyamine metabolic process	3.390463e-3
GO:0070417	cellular response to cold	3.412234e-3
GO:0060154	cellular process regulating host cell cycle in response to virus	3.436053e-3
GO:0009145	purine nucleoside triphosphate biosynthetic process	3.442541e-3
GO:0030449	regulation of complement activation	3.462444e-3
GO:0043217	myelin maintenance	3.518483e-3
GO:0015862	uridine transport	3.545793e-3
GO:0003184	pulmonary valve morphogenesis	3.545793e-3
GO:0016573	histone acetylation	3.548785e-3
GO:0043647	inositol phosphate metabolic process	3.553882e-3
GO:0021629	olfactory nerve structural organization	3.557276e-3
GO:0019264	glycine biosynthetic process from serine	3.557276e-3
GO:0046931	pore complex assembly	3.591989e-3
GO:0034470	ncRNA processing	3.607886e-3
GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus	3.611004e-3
GO:0001667	ameboidal cell migration	3.684683e-3
GO:0060290	transdifferentiation	3.690556e-3
GO:0045581	negative regulation of T cell differentiation	3.728563e-3
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	3.818316e-3
GO:0030327	prenylated protein catabolic process	3.818316e-3
GO:0008295	spermidine biosynthetic process	3.818316e-3
GO:0050820	positive regulation of coagulation	3.822762e-3
GO:0000414	regulation of histone H3-K36 methylation	3.857764e-3
GO:2000836	positive regulation of androgen secretion	3.886547e-3
GO:2000500	positive regulation of induction of apoptosis in response to chemical stimulus	3.886547e-3
GO:0046514	ceramide catabolic process	4.017999e-3
GO:0035922	foramen ovale closure	4.035072e-3
GO:0060577	pulmonary vein morphogenesis	4.035072e-3
GO:0034241	positive regulation of macrophage fusion	4.035072e-3
GO:0042407	cristae formation	4.035072e-3
GO:0003193	pulmonary valve formation	4.035072e-3
GO:0016191	synaptic vesicle uncoating	4.035072e-3
GO:0032074	negative regulation of nuclease activity	4.035072e-3
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	4.095209e-3
GO:0021784	postganglionic parasympathetic nervous system development	4.140006e-3
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	4.148266e-3
GO:0030865	cortical cytoskeleton organization	4.158411e-3
GO:0006312	mitotic recombination	4.162597e-3
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	4.229814e-3
GO:0022417	protein maturation by protein folding	4.329635e-3
GO:0030187	melatonin biosynthetic process	4.334043e-3
GO:0021993	initiation of neural tube closure	4.455530e-3
GO:0045726	positive regulation of integrin biosynthetic process	4.494571e-3
GO:0034660	ncRNA metabolic process	4.519012e-3
GO:0060263	regulation of respiratory burst	4.560198e-3
GO:0021602	cranial nerve morphogenesis	4.632913e-3
GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway	4.680413e-3
GO:0072285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	4.680413e-3
GO:0060248	detection of cell density by contact stimulus involved in contact inhibition	4.680413e-3
GO:0007371	ventral midline determination	4.680413e-3
GO:0009150	purine ribonucleotide metabolic process	4.804641e-3
GO:0002712	regulation of B cell mediated immunity	4.840495e-3
GO:0046856	phosphatidylinositol dephosphorylation	4.918349e-3
GO:0015800	acidic amino acid transport	4.926890e-3
GO:0006754	ATP biosynthetic process	4.966072e-3
GO:0008347	glial cell migration	4.979206e-3
GO:0042762	regulation of sulfur metabolic process	5.004145e-3
GO:0021542	dentate gyrus development	5.021494e-3
GO:0090201	negative regulation of release of cytochrome c from mitochondria	5.034288e-3
GO:0016188	synaptic vesicle maturation	5.034288e-3
GO:0015813	L-glutamate transport	5.054564e-3
GO:0043277	apoptotic cell clearance	5.086114e-3
GO:0060300	regulation of cytokine activity	5.246973e-3
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	5.305658e-3
GO:0044070	regulation of anion transport	5.444790e-3
GO:0060040	retinal bipolar neuron differentiation	5.485592e-3
GO:0021759	globus pallidus development	5.518039e-3
GO:0071361	cellular response to ethanol	5.784538e-3
GO:0046778	modification by virus of host mRNA processing	5.915866e-3
GO:0021524	visceral motor neuron differentiation	5.915866e-3
GO:0009259	ribonucleotide metabolic process	5.916461e-3
GO:0002889	regulation of immunoglobulin mediated immune response	5.951324e-3
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	6.025238e-3
GO:0032218	riboflavin transport	6.071146e-3
GO:0007089	traversing start control point of mitotic cell cycle	6.108848e-3
GO:0051176	positive regulation of sulfur metabolic process	6.113848e-3
GO:0032429	regulation of phospholipase A2 activity	6.157734e-3
GO:0002092	positive regulation of receptor internalization	6.319096e-3
GO:0007625	grooming behavior	6.421404e-3
GO:0032876	negative regulation of DNA endoreduplication	6.444231e-3
GO:0019054	modulation by virus of host cellular process	6.502924e-3
GO:0048818	positive regulation of hair follicle maturation	6.513674e-3
GO:0042538	hyperosmotic salinity response	6.513674e-3
GO:0016139	glycoside catabolic process	6.691586e-3
GO:0061198	fungiform papilla formation	6.691586e-3
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	6.692873e-3
GO:0001510	RNA methylation	6.713222e-3
GO:0002642	positive regulation of immunoglobulin biosynthetic process	6.810648e-3
GO:0007468	regulation of rhodopsin gene expression	6.810648e-3
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	6.834320e-3
GO:0070253	somatostatin secretion	6.834320e-3
GO:0008594	photoreceptor cell morphogenesis	6.834320e-3
GO:0032812	positive regulation of epinephrine secretion	6.834320e-3
GO:0071526	semaphorin-plexin signaling pathway	6.848318e-3
GO:0032232	negative regulation of actin filament bundle assembly	6.848318e-3
GO:2000639	negative regulation of SREBP-mediated signaling pathway	6.884756e-3
GO:2000346	negative regulation of hepatocyte proliferation	6.884756e-3
GO:0060374	mast cell differentiation	6.976271e-3
GO:0070662	mast cell proliferation	6.976271e-3
GO:0014707	branchiomeric skeletal muscle development	6.976271e-3
GO:0033133	positive regulation of glucokinase activity	6.986959e-3
GO:0015991	ATP hydrolysis coupled proton transport	7.039416e-3
GO:0046782	regulation of viral transcription	7.098884e-3
GO:2001054	negative regulation of mesenchymal cell apoptosis	7.287892e-3
GO:0019242	methylglyoxal biosynthetic process	7.287892e-3
GO:0043299	leukocyte degranulation	7.293809e-3
GO:0043491	protein kinase B signaling cascade	7.299173e-3
GO:0060430	lung saccule development	7.427490e-3
GO:0048843	negative regulation of axon extension involved in axon guidance	7.439885e-3
GO:0043331	response to dsRNA	7.440568e-3
GO:0048332	mesoderm morphogenesis	7.602250e-3
GO:0001707	mesoderm formation	7.701424e-3
GO:0010727	negative regulation of hydrogen peroxide metabolic process	7.720021e-3
GO:0048147	negative regulation of fibroblast proliferation	7.755109e-3
GO:0043966	histone H3 acetylation	7.922178e-3
GO:0032957	inositol trisphosphate metabolic process	7.935817e-3
GO:0008033	tRNA processing	8.042210e-3
GO:0032922	circadian regulation of gene expression	8.147734e-3
GO:0097116	gephyrin clustering	8.313299e-3
GO:0051001	negative regulation of nitric-oxide synthase activity	8.314503e-3
GO:0048280	vesicle fusion with Golgi apparatus	8.347001e-3
GO:0001306	age-dependent response to oxidative stress	8.375022e-3
GO:0044273	sulfur compound catabolic process	8.652805e-3
GO:0048524	positive regulation of viral reproduction	8.653657e-3
GO:0034619	cellular chaperone-mediated protein complex assembly	8.758982e-3
GO:0006208	pyrimidine base catabolic process	8.777612e-3
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	8.777612e-3
GO:0050821	protein stabilization	8.812924e-3
GO:0018199	peptidyl-glutamine modification	8.836600e-3
GO:0043393	regulation of protein binding	9.056218e-3
GO:0050666	regulation of homocysteine metabolic process	9.204275e-3
GO:0016180	snRNA processing	9.356806e-3
GO:0001778	plasma membrane repair	9.532027e-3
GO:0019637	organophosphate metabolic process	9.535648e-3
GO:0045830	positive regulation of isotype switching	9.563874e-3
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	9.582312e-3
GO:0002275	myeloid cell activation involved in immune response	9.650168e-3
GO:0009207	purine ribonucleoside triphosphate catabolic process	9.669684e-3
GO:0090362	positive regulation of platelet-derived growth factor production	9.841372e-3
GO:0090271	positive regulation of fibroblast growth factor production	9.841372e-3
GO:0090336	positive regulation of brown fat cell differentiation	9.841372e-3
GO:0043543	protein acylation	9.962313e-3
GO:0014068	positive regulation of phosphatidylinositol 3-kinase cascade	9.993969e-3
GO:0045627	positive regulation of T-helper 1 cell differentiation	1.004416e-2
GO:0002149	hypochlorous acid biosynthetic process	1.006386e-2
GO:0006344	maintenance of chromatin silencing	1.006386e-2
GO:0045911	positive regulation of DNA recombination	1.052155e-2
GO:0001821	histamine secretion	1.068591e-2
GO:0097104	postsynaptic membrane assembly	1.070908e-2
GO:0097119	postsynaptic density protein 95 clustering	1.070908e-2
GO:0051775	response to redox state	1.074592e-2
GO:0071634	regulation of transforming growth factor beta production	1.075192e-2
GO:0009637	response to blue light	1.076308e-2
GO:0050668	positive regulation of homocysteine metabolic process	1.078431e-2
GO:0070682	proteasome regulatory particle assembly	1.078431e-2
GO:0045963	negative regulation of dopamine metabolic process	1.078431e-2
GO:0002897	positive regulation of central B cell tolerance induction	1.078431e-2
GO:0002508	central tolerance induction	1.078431e-2
GO:0071312	cellular response to alkaloid	1.085737e-2
GO:0009146	purine nucleoside triphosphate catabolic process	1.085912e-2
GO:0010042	response to manganese ion	1.095343e-2
GO:0006782	protoporphyrinogen IX biosynthetic process	1.098524e-2
GO:0070194	synaptonemal complex disassembly	1.098524e-2
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	1.098524e-2
GO:0019448	L-cysteine catabolic process	1.098524e-2
GO:0008216	spermidine metabolic process	1.098524e-2
GO:0006102	isocitrate metabolic process	1.114126e-2
GO:0045104	intermediate filament cytoskeleton organization	1.114507e-2
GO:0046687	response to chromate	1.132846e-2
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	1.132846e-2
GO:0033986	response to methanol	1.132846e-2
GO:0019369	arachidonic acid metabolic process	1.141329e-2
GO:0043089	positive regulation of Cdc42 GTPase activity	1.141895e-2
GO:0030219	megakaryocyte differentiation	1.148387e-2
GO:0007498	mesoderm development	1.163618e-2
GO:0050766	positive regulation of phagocytosis	1.171514e-2
GO:0050746	regulation of lipoprotein metabolic process	1.183702e-2
GO:0006564	L-serine biosynthetic process	1.192836e-2
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	1.195134e-2
GO:0009154	purine ribonucleotide catabolic process	1.200481e-2
GO:0045872	positive regulation of rhodopsin gene expression	1.201224e-2
GO:0051102	DNA ligation involved in DNA recombination	1.201224e-2
GO:0071469	cellular response to alkalinity	1.201224e-2
GO:0046380	N-acetylneuraminate biosynthetic process	1.201224e-2
GO:0006258	UDP-glucose catabolic process	1.201224e-2
GO:0009446	putrescine biosynthetic process	1.201224e-2
GO:0035427	purine nucleoside transmembrane transport	1.201224e-2
GO:0000722	telomere maintenance via recombination	1.213103e-2
GO:0046416	D-amino acid metabolic process	1.222639e-2
GO:0009586	rhodopsin mediated phototransduction	1.224273e-2
GO:2000296	negative regulation of hydrogen peroxide catabolic process	1.225057e-2
GO:0033342	negative regulation of collagen binding	1.225057e-2
GO:0034971	histone H3-R17 methylation	1.225057e-2
GO:0042117	monocyte activation	1.247167e-2
GO:0051894	positive regulation of focal adhesion assembly	1.256345e-2
GO:0032364	oxygen homeostasis	1.279113e-2
GO:0021892	cerebral cortex GABAergic interneuron differentiation	1.290940e-2
GO:0007339	binding of sperm to zona pellucida	1.290940e-2
GO:2000334	positive regulation of blood microparticle formation	1.292823e-2
GO:0010269	response to selenium ion	1.293546e-2
GO:0046148	pigment biosynthetic process	1.302517e-2
GO:0002040	sprouting angiogenesis	1.302638e-2
GO:0009438	methylglyoxal metabolic process	1.302983e-2
GO:0030047	actin modification	1.308299e-2
GO:0032259	methylation	1.309984e-2
GO:0007253	cytoplasmic sequestering of NF-kappaB	1.322300e-2
GO:0010763	positive regulation of fibroblast migration	1.324353e-2
GO:0042074	cell migration involved in gastrulation	1.342369e-2
GO:0061136	regulation of proteasomal protein catabolic process	1.346930e-2
GO:0003032	detection of oxygen	1.348083e-2
GO:0034435	cholesterol esterification	1.349071e-2
GO:0033299	secretion of lysosomal enzymes	1.349071e-2
GO:0048842	positive regulation of axon extension involved in axon guidance	1.353467e-2
GO:0044328	canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration	1.353467e-2
GO:0044330	canonical Wnt receptor signaling pathway involved in positive regulation of wound healing	1.353467e-2
GO:0044329	canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion	1.353467e-2
GO:0033131	regulation of glucokinase activity	1.359353e-2
GO:0010107	potassium ion import	1.368647e-2
GO:0034259	negative regulation of Rho GTPase activity	1.368843e-2
GO:0022007	convergent extension involved in neural plate elongation	1.368843e-2
GO:0003085	negative regulation of systemic arterial blood pressure	1.377597e-2
GO:0001893	maternal placenta development	1.381970e-2
GO:0045471	response to ethanol	1.413765e-2
GO:0051588	regulation of neurotransmitter transport	1.418169e-2
GO:0042098	T cell proliferation	1.434347e-2
GO:0051795	positive regulation of catagen	1.441884e-2
GO:0032515	negative regulation of phosphoprotein phosphatase activity	1.462863e-2
GO:2000773	negative regulation of cellular senescence	1.468687e-2
GO:0043697	cell dedifferentiation	1.468687e-2
GO:0032916	positive regulation of transforming growth factor beta3 production	1.476523e-2
GO:0033578	protein glycosylation in Golgi	1.502864e-2
GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine	1.502864e-2
GO:0019934	cGMP-mediated signaling	1.507329e-2
GO:0006400	tRNA modification	1.515366e-2
GO:0003175	tricuspid valve development	1.518292e-2
GO:0006406	mRNA export from nucleus	1.523102e-2
GO:0048861	leukemia inhibitory factor signaling pathway	1.538863e-2
GO:0048708	astrocyte differentiation	1.547084e-2
GO:0033143	regulation of steroid hormone receptor signaling pathway	1.550679e-2
GO:0006383	transcription from RNA polymerase III promoter	1.555656e-2
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.559274e-2
GO:0048260	positive regulation of receptor-mediated endocytosis	1.565973e-2
GO:0031647	regulation of protein stability	1.573253e-2
GO:0016137	glycoside metabolic process	1.575639e-2
GO:0032201	telomere maintenance via semi-conservative replication	1.587336e-2
GO:0070670	response to interleukin-4	1.587982e-2
GO:0051608	histamine transport	1.590987e-2
GO:0071777	positive regulation of cell cycle cytokinesis	1.612514e-2
GO:0048846	axon extension involved in axon guidance	1.612514e-2
GO:0051028	mRNA transport	1.616248e-2
GO:0000730	DNA recombinase assembly	1.617246e-2
GO:0021660	rhombomere 3 formation	1.620230e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.716967e-8
GO:0043508	negative regulation of JUN kinase activity	2.193205e-8
GO:0048240	sperm capacitation	6.332988e-8
GO:0072132	mesenchyme morphogenesis	1.469993e-7
GO:0006476	protein deacetylation	4.173960e-7
GO:0048818	positive regulation of hair follicle maturation	4.381561e-7
GO:0061181	regulation of chondrocyte development	4.456771e-7
GO:0035601	protein deacylation	6.473867e-7
GO:0006302	double-strand break repair	7.363463e-7
GO:0051795	positive regulation of catagen	1.239897e-6
GO:0090244	Wnt receptor signaling pathway involved in somitogenesis	1.309265e-6
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	1.378382e-6
GO:0070509	calcium ion import	2.492601e-6
GO:0032915	positive regulation of transforming growth factor beta2 production	3.399641e-6
GO:0060461	right lung morphogenesis	3.440904e-6
GO:0060446	branching involved in open tracheal system development	3.440904e-6
GO:0090131	mesenchyme migration	3.440904e-6
GO:0048613	embryonic ectodermal digestive tract morphogenesis	3.440904e-6
GO:0014822	detection of wounding	3.440904e-6
GO:0048371	lateral mesodermal cell differentiation	3.440904e-6
GO:0045599	negative regulation of fat cell differentiation	3.641275e-6
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	3.644099e-6
GO:0022417	protein maturation by protein folding	3.644099e-6
GO:0060351	cartilage development involved in endochondral bone morphogenesis	3.900692e-6
GO:0051438	regulation of ubiquitin-protein ligase activity	4.524157e-6
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	4.565237e-6
GO:0046902	regulation of mitochondrial membrane permeability	4.720657e-6
GO:0070383	DNA cytosine deamination	4.962931e-6
GO:0010529	negative regulation of transposition	4.962931e-6
GO:0016575	histone deacetylation	7.900760e-6
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	1.577273e-5
GO:0090076	relaxation of skeletal muscle	1.577273e-5
GO:0010045	response to nickel ion	1.588278e-5
GO:0014819	regulation of skeletal muscle contraction	1.624935e-5
GO:0006707	cholesterol catabolic process	1.624935e-5
GO:0034661	ncRNA catabolic process	1.706369e-5
GO:0032423	regulation of mismatch repair	1.899376e-5
GO:0090343	positive regulation of cell aging	2.099751e-5
GO:0002883	regulation of hypersensitivity	2.317543e-5
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	2.746323e-5
GO:0071214	cellular response to abiotic stimulus	2.767719e-5
GO:0003416	endochondral bone growth	2.873946e-5
GO:0008635	activation of caspase activity by cytochrome c	3.167070e-5
GO:0046514	ceramide catabolic process	4.615141e-5
GO:0032674	regulation of interleukin-5 production	4.624521e-5
GO:0060364	frontal suture morphogenesis	4.794795e-5
GO:0051561	elevation of mitochondrial calcium ion concentration	4.794795e-5
GO:2001020	regulation of response to DNA damage stimulus	5.337475e-5
GO:0071636	positive regulation of transforming growth factor beta production	5.549549e-5
GO:0060350	endochondral bone morphogenesis	5.676983e-5
GO:0070166	enamel mineralization	5.870896e-5
GO:0015931	nucleobase-containing compound transport	5.930268e-5
GO:0016139	glycoside catabolic process	6.070517e-5
GO:0051403	stress-activated MAPK cascade	6.262656e-5
GO:0090273	regulation of somatostatin secretion	6.301062e-5
GO:0045401	positive regulation of interleukin-3 biosynthetic process	6.383433e-5
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	6.383433e-5
GO:0000733	DNA strand renaturation	6.437404e-5
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	6.623773e-5
GO:0033599	regulation of mammary gland epithelial cell proliferation	7.444079e-5
GO:0035880	embryonic nail plate morphogenesis	8.065744e-5
GO:0090399	replicative senescence	8.221844e-5
GO:0006646	phosphatidylethanolamine biosynthetic process	8.577661e-5
GO:0009081	branched chain family amino acid metabolic process	8.897738e-5
GO:0051482	elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger	9.730029e-5
GO:0001820	serotonin secretion	9.852488e-5
GO:0070602	regulation of centromeric sister chromatid cohesion	1.002766e-4
GO:0044091	membrane biogenesis	1.002766e-4
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	1.042840e-4
GO:0001798	positive regulation of type IIa hypersensitivity	1.065447e-4
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	1.083174e-4
GO:0032049	cardiolipin biosynthetic process	1.083174e-4
GO:0045123	cellular extravasation	1.144707e-4
GO:0071257	cellular response to electrical stimulus	1.352307e-4
GO:0031577	spindle checkpoint	1.352307e-4
GO:0045617	negative regulation of keratinocyte differentiation	1.371490e-4
GO:0007569	cell aging	1.437827e-4
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	1.569834e-4
GO:0071218	cellular response to misfolded protein	1.721940e-4
GO:0071173	spindle assembly checkpoint	1.819378e-4
GO:0008588	release of cytoplasmic sequestered NF-kappaB	1.819378e-4
GO:0051693	actin filament capping	1.881936e-4
GO:0051923	sulfation	1.888482e-4
GO:0000413	protein peptidyl-prolyl isomerization	1.936461e-4
GO:0018230	peptidyl-L-cysteine S-palmitoylation	1.991109e-4
GO:0060154	cellular process regulating host cell cycle in response to virus	2.091156e-4
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	2.191117e-4
GO:0016032	viral reproduction	2.205635e-4
GO:0006837	serotonin transport	2.229249e-4
GO:0032469	endoplasmic reticulum calcium ion homeostasis	2.371530e-4
GO:0021535	cell migration in hindbrain	2.371530e-4
GO:0043570	maintenance of DNA repeat elements	2.434720e-4
GO:0021932	hindbrain radial glia guided cell migration	2.437915e-4
GO:0010948	negative regulation of cell cycle process	2.503108e-4
GO:0072189	ureter development	2.595215e-4
GO:0006354	transcription elongation, DNA-dependent	2.619385e-4
GO:0030157	pancreatic juice secretion	2.830654e-4
GO:0046670	positive regulation of retinal cell programmed cell death	2.858281e-4
GO:0002525	acute inflammatory response to non-antigenic stimulus	2.858281e-4
GO:0016142	O-glycoside catabolic process	2.858281e-4
GO:0060010	Sertoli cell fate commitment	2.913996e-4
GO:0002886	regulation of myeloid leukocyte mediated immunity	2.980243e-4
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	3.076496e-4
GO:0051340	regulation of ligase activity	3.079029e-4
GO:0008615	pyridoxine biosynthetic process	3.191781e-4
GO:0071174	mitotic cell cycle spindle checkpoint	3.209208e-4
GO:0032853	positive regulation of Ran GTPase activity	3.256284e-4
GO:0032383	regulation of intracellular cholesterol transport	3.256284e-4
GO:0030834	regulation of actin filament depolymerization	3.322516e-4
GO:0050658	RNA transport	3.441315e-4
GO:0021631	optic nerve morphogenesis	3.611577e-4
GO:0045198	establishment of epithelial cell apical/basal polarity	3.663187e-4
GO:0006184	GTP catabolic process	3.733839e-4
GO:0006656	phosphatidylcholine biosynthetic process	3.890915e-4
GO:0006706	steroid catabolic process	3.927812e-4
GO:0003272	endocardial cushion formation	3.936002e-4
GO:0090342	regulation of cell aging	3.962465e-4
GO:0071634	regulation of transforming growth factor beta production	3.976652e-4
GO:0006820	anion transport	3.996241e-4
GO:0008608	attachment of spindle microtubules to kinetochore	4.019722e-4
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	4.070004e-4
GO:0002885	positive regulation of hypersensitivity	4.319022e-4
GO:0090005	negative regulation of establishment of protein localization in plasma membrane	4.350055e-4
GO:0042396	phosphagen biosynthetic process	4.350055e-4
GO:0006482	protein demethylation	4.360393e-4
GO:0048014	Tie receptor signaling pathway	4.397935e-4
GO:0006513	protein monoubiquitination	4.569039e-4
GO:0002536	respiratory burst involved in inflammatory response	4.590749e-4
GO:0042772	DNA damage response, signal transduction resulting in transcription	4.704218e-4
GO:0045579	positive regulation of B cell differentiation	4.740251e-4
GO:0072133	metanephric mesenchyme morphogenesis	4.807129e-4
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	4.943770e-4
GO:0006713	glucocorticoid catabolic process	4.943770e-4
GO:0006368	transcription elongation from RNA polymerase II promoter	4.967766e-4
GO:0045869	negative regulation of retroviral genome replication	5.119286e-4
GO:0045628	regulation of T-helper 2 cell differentiation	5.121208e-4
GO:0003203	endocardial cushion morphogenesis	5.442440e-4
GO:0016236	macroautophagy	5.551645e-4
GO:0071622	regulation of granulocyte chemotaxis	5.614286e-4
GO:0032656	regulation of interleukin-13 production	5.811603e-4
GO:2000053	regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	5.819408e-4
GO:0006999	nuclear pore organization	5.819408e-4
GO:0002679	respiratory burst involved in defense response	5.868210e-4
GO:0046580	negative regulation of Ras protein signal transduction	5.942457e-4
GO:0006403	RNA localization	5.952062e-4
GO:0060326	cell chemotaxis	6.099099e-4
GO:0070059	apoptosis in response to endoplasmic reticulum stress	6.158685e-4
GO:0032048	cardiolipin metabolic process	6.540151e-4
GO:0046314	phosphocreatine biosynthetic process	6.591623e-4
GO:0051865	protein autoubiquitination	6.622881e-4
GO:0007094	mitotic cell cycle spindle assembly checkpoint	6.905904e-4
GO:0090403	oxidative stress-induced premature senescence	6.905904e-4
GO:0016574	histone ubiquitination	7.059031e-4
GO:0031281	positive regulation of cyclase activity	7.236827e-4
GO:2000001	regulation of DNA damage checkpoint	7.482999e-4
GO:0045762	positive regulation of adenylate cyclase activity	7.522192e-4
GO:0006282	regulation of DNA repair	7.812906e-4
GO:0010467	gene expression	8.112787e-4
GO:0035089	establishment of apical/basal cell polarity	8.396324e-4
GO:0016075	rRNA catabolic process	8.561798e-4
GO:0051349	positive regulation of lyase activity	8.855799e-4
GO:0001970	positive regulation of activation of membrane attack complex	8.964299e-4
GO:0042921	glucocorticoid receptor signaling pathway	9.067735e-4
GO:0050832	defense response to fungus	9.174410e-4
GO:0009303	rRNA transcription	9.280248e-4
GO:0016137	glycoside metabolic process	9.600449e-4
GO:0022900	electron transport chain	9.715499e-4
GO:0048246	macrophage chemotaxis	9.904806e-4
GO:0051058	negative regulation of small GTPase mediated signal transduction	1.038015e-3
GO:0002268	follicular dendritic cell differentiation	1.059894e-3
GO:0046373	L-arabinose metabolic process	1.064478e-3
GO:0035106	operant conditioning	1.064478e-3
GO:0038007	netrin-activated signaling pathway	1.065211e-3
GO:0032119	sequestering of zinc ion	1.065211e-3
GO:0006457	protein folding	1.070943e-3
GO:0046039	GTP metabolic process	1.073361e-3
GO:0034470	ncRNA processing	1.073465e-3
GO:0090042	tubulin deacetylation	1.085157e-3
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	1.085157e-3
GO:0007630	jump response	1.085157e-3
GO:0070846	Hsp90 deacetylation	1.085157e-3
GO:0001966	thigmotaxis	1.085157e-3
GO:0071526	semaphorin-plexin signaling pathway	1.096380e-3
GO:0014032	neural crest cell development	1.108311e-3
GO:0008637	apoptotic mitochondrial changes	1.114619e-3
GO:0006658	phosphatidylserine metabolic process	1.132564e-3
GO:0071482	cellular response to light stimulus	1.147475e-3
GO:0016072	rRNA metabolic process	1.196930e-3
GO:0001756	somitogenesis	1.222449e-3
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	1.234895e-3
GO:0032226	positive regulation of synaptic transmission, dopaminergic	1.245274e-3
GO:0010312	detoxification of zinc ion	1.245274e-3
GO:0072321	chaperone-mediated protein transport	1.251375e-3
GO:0033601	positive regulation of mammary gland epithelial cell proliferation	1.258449e-3
GO:0048148	behavioral response to cocaine	1.258449e-3
GO:0009082	branched chain family amino acid biosynthetic process	1.258449e-3
GO:0006396	RNA processing	1.272264e-3
GO:0001969	regulation of activation of membrane attack complex	1.274360e-3
GO:0043537	negative regulation of blood vessel endothelial cell migration	1.299554e-3
GO:0043305	negative regulation of mast cell degranulation	1.308309e-3
GO:0033603	positive regulation of dopamine secretion	1.315584e-3
GO:0001682	tRNA 5'-leader removal	1.435554e-3
GO:0051041	positive regulation of calcium-independent cell-cell adhesion	1.435554e-3
GO:0071352	cellular response to interleukin-2	1.435554e-3
GO:0016078	tRNA catabolic process	1.435554e-3
GO:0021933	radial glia guided migration of cerebellar granule cell	1.461890e-3
GO:0051444	negative regulation of ubiquitin-protein ligase activity	1.503195e-3
GO:0007190	activation of adenylate cyclase activity	1.526585e-3
GO:0006654	phosphatidic acid biosynthetic process	1.540826e-3
GO:0018208	peptidyl-proline modification	1.565009e-3
GO:0001755	neural crest cell migration	1.587769e-3
GO:0046949	fatty-acyl-CoA biosynthetic process	1.709381e-3
GO:0015706	nitrate transport	1.709381e-3
GO:0009450	gamma-aminobutyric acid catabolic process	1.709381e-3
GO:0048002	antigen processing and presentation of peptide antigen	1.717938e-3
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	1.736920e-3
GO:0021554	optic nerve development	1.752238e-3
GO:0031958	corticosteroid receptor signaling pathway	1.773446e-3
GO:0032754	positive regulation of interleukin-5 production	1.822612e-3
GO:0043525	positive regulation of neuron apoptosis	1.857255e-3
GO:0030835	negative regulation of actin filament depolymerization	1.876949e-3
GO:0043029	T cell homeostasis	1.878848e-3
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway	1.977351e-3
GO:0042637	catagen	1.977883e-3
GO:0006515	misfolded or incompletely synthesized protein catabolic process	1.977883e-3
GO:0016577	histone demethylation	1.994963e-3
GO:0034260	negative regulation of GTPase activity	2.055558e-3
GO:0033004	negative regulation of mast cell activation	2.055558e-3
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	2.058211e-3
GO:0008208	C21-steroid hormone catabolic process	2.058211e-3
GO:0021997	neural plate axis specification	2.066938e-3
GO:0033160	positive regulation of protein import into nucleus, translocation	2.073439e-3
GO:0042254	ribosome biogenesis	2.081426e-3
GO:0015711	organic anion transport	2.085295e-3
GO:0032696	negative regulation of interleukin-13 production	2.109885e-3
GO:0018199	peptidyl-glutamine modification	2.172094e-3
GO:0003417	growth plate cartilage development	2.172881e-3
GO:0001788	antibody-dependent cellular cytotoxicity	2.188333e-3
GO:0046502	uroporphyrinogen III metabolic process	2.188333e-3
GO:0042733	embryonic digit morphogenesis	2.299433e-3
GO:0045006	DNA deamination	2.305091e-3
GO:0002572	pro-T cell differentiation	2.305091e-3
GO:0070189	kynurenine metabolic process	2.345076e-3
GO:0001569	patterning of blood vessels	2.359702e-3
GO:0010954	positive regulation of protein processing	2.412413e-3
GO:0006555	methionine metabolic process	2.508922e-3
GO:0030837	negative regulation of actin filament polymerization	2.515333e-3
GO:0006839	mitochondrial transport	2.520260e-3
GO:0060221	retinal rod cell differentiation	2.521104e-3
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	2.521104e-3
GO:0046474	glycerophospholipid biosynthetic process	2.552519e-3
GO:0045761	regulation of adenylate cyclase activity	2.556947e-3
GO:0043623	cellular protein complex assembly	2.557011e-3
GO:0015813	L-glutamate transport	2.558421e-3
GO:0007521	muscle cell fate determination	2.561172e-3
GO:0050999	regulation of nitric-oxide synthase activity	2.588092e-3
GO:0030917	midbrain-hindbrain boundary development	2.619163e-3
GO:0051028	mRNA transport	2.635783e-3
GO:0048050	post-embryonic eye morphogenesis	2.642610e-3
GO:0061035	regulation of cartilage development	2.697951e-3
GO:0060349	bone morphogenesis	2.707483e-3
GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity	2.712328e-3
GO:0002027	regulation of heart rate	2.715064e-3
GO:0034644	cellular response to UV	2.769473e-3
GO:0021943	formation of radial glial scaffolds	2.792439e-3
GO:0030851	granulocyte differentiation	2.868272e-3
GO:0061298	retina vasculature development in camera-type eye	2.872360e-3
GO:0018202	peptidyl-histidine modification	2.936064e-3
GO:0060547	negative regulation of necrotic cell death	2.947674e-3
GO:0019054	modulation by virus of host cellular process	2.984878e-3
GO:0002326	B cell lineage commitment	2.984878e-3
GO:0007638	mechanosensory behavior	3.049774e-3
GO:0071353	cellular response to interleukin-4	3.054885e-3
GO:0009083	branched chain family amino acid catabolic process	3.056772e-3
GO:0006659	phosphatidylserine biosynthetic process	3.069817e-3
GO:0034641	cellular nitrogen compound metabolic process	3.091157e-3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	3.102017e-3
GO:0061312	BMP signaling pathway involved in heart development	3.102017e-3
GO:0048145	regulation of fibroblast proliferation	3.114776e-3
GO:0070842	aggresome assembly	3.146742e-3
GO:0030210	heparin biosynthetic process	3.146742e-3
GO:0051255	spindle midzone assembly	3.146742e-3
GO:0048368	lateral mesoderm development	3.218260e-3
GO:0000045	autophagic vacuole assembly	3.287316e-3
GO:0016070	RNA metabolic process	3.406744e-3
GO:0010518	positive regulation of phospholipase activity	3.410582e-3
GO:0032736	positive regulation of interleukin-13 production	3.421996e-3
GO:2000297	negative regulation of synapse maturation	3.424941e-3
GO:0014033	neural crest cell differentiation	3.471657e-3
GO:2000054	negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	3.482993e-3
GO:0006477	protein sulfation	3.496690e-3
GO:0030258	lipid modification	3.513102e-3
GO:0031279	regulation of cyclase activity	3.520220e-3
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	3.537046e-3
GO:0030593	neutrophil chemotaxis	3.537046e-3
GO:0010824	regulation of centrosome duplication	3.552970e-3
GO:0045989	positive regulation of striated muscle contraction	3.565664e-3
GO:0009086	methionine biosynthetic process	3.592567e-3
GO:0032714	negative regulation of interleukin-5 production	3.594864e-3
GO:0060997	dendritic spine morphogenesis	3.617137e-3
GO:0042823	pyridoxal phosphate biosynthetic process	3.621418e-3
GO:0051238	sequestering of metal ion	3.634919e-3
GO:0006370	mRNA capping	3.634919e-3
GO:0007202	activation of phospholipase C activity	3.638674e-3
GO:0006366	transcription from RNA polymerase II promoter	3.644313e-3
GO:0006779	porphyrin-containing compound biosynthetic process	3.645408e-3
GO:0002524	hypersensitivity	3.656322e-3
GO:0043304	regulation of mast cell degranulation	3.691081e-3
GO:0006913	nucleocytoplasmic transport	3.696670e-3
GO:0002309	T cell proliferation involved in immune response	3.818992e-3
GO:0060363	cranial suture morphogenesis	3.921835e-3
GO:0060019	radial glial cell differentiation	3.932637e-3
GO:0010718	positive regulation of epithelial to mesenchymal transition	3.937574e-3
GO:0051339	regulation of lyase activity	3.948927e-3
GO:0045091	regulation of retroviral genome replication	3.966704e-3
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	4.058242e-3
GO:0070584	mitochondrion morphogenesis	4.109960e-3
GO:0002149	hypochlorous acid biosynthetic process	4.113051e-3
GO:0034111	negative regulation of homotypic cell-cell adhesion	4.113051e-3
GO:0031161	phosphatidylinositol catabolic process	4.210367e-3
GO:0016140	O-glycoside metabolic process	4.210367e-3
GO:0001811	negative regulation of type I hypersensitivity	4.210367e-3
GO:0002638	negative regulation of immunoglobulin production	4.210367e-3
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport	4.220536e-3
GO:0002861	regulation of inflammatory response to antigenic stimulus	4.223939e-3
GO:0061304	retinal blood vessel morphogenesis	4.249542e-3
GO:0035411	catenin import into nucleus	4.310951e-3
GO:0006599	phosphagen metabolic process	4.310951e-3
GO:0070613	regulation of protein processing	4.381578e-3
GO:0050792	regulation of viral reproduction	4.417630e-3
GO:0060591	chondroblast differentiation	4.532126e-3
GO:0021903	rostrocaudal neural tube patterning	4.535588e-3
GO:0051443	positive regulation of ubiquitin-protein ligase activity	4.603474e-3
GO:0008033	tRNA processing	4.629983e-3
GO:0048144	fibroblast proliferation	4.635959e-3
GO:0035645	enteric smooth muscle cell differentiation	4.635959e-3
GO:0002024	diet induced thermogenesis	4.635959e-3
GO:0007497	posterior midgut development	4.635959e-3
GO:0032094	response to food	4.679877e-3
GO:0030865	cortical cytoskeleton organization	4.831646e-3
GO:0032910	regulation of transforming growth factor beta3 production	4.892393e-3
GO:0021532	neural tube patterning	4.931241e-3
GO:0048147	negative regulation of fibroblast proliferation	5.025011e-3
GO:0045624	positive regulation of T-helper cell differentiation	5.047706e-3
GO:0043923	positive regulation by host of viral transcription	5.087179e-3
GO:0001504	neurotransmitter uptake	5.093634e-3
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	5.104206e-3
GO:2000078	positive regulation of type B pancreatic cell development	5.188802e-3
GO:0060710	chorio-allantoic fusion	5.212911e-3
GO:0060674	placenta blood vessel development	5.263402e-3
GO:0003148	outflow tract septum morphogenesis	5.387562e-3
GO:0090003	regulation of establishment of protein localization in plasma membrane	5.427456e-3
GO:0007406	negative regulation of neuroblast proliferation	5.442626e-3
GO:0070933	histone H4 deacetylation	5.447542e-3
GO:0014031	mesenchymal cell development	5.480499e-3
GO:0048820	hair follicle maturation	5.581845e-3
GO:0006364	rRNA processing	5.584752e-3
GO:0030223	neutrophil differentiation	5.650396e-3
GO:0072208	metanephric smooth muscle tissue development	5.664002e-3
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	5.664002e-3
GO:0072259	metanephric interstitial cell development	5.664002e-3
GO:0072184	renal vesicle progenitor cell differentiation	5.664002e-3
GO:0072169	specification of posterior mesonephric tubule identity	5.664002e-3
GO:0072168	specification of anterior mesonephric tubule identity	5.664002e-3
GO:0046092	deoxycytidine metabolic process	5.696667e-3
GO:0016557	peroxisome membrane biogenesis	5.696667e-3
GO:0032608	interferon-beta production	5.696667e-3
GO:0043084	penile erection	5.719360e-3
GO:0009826	unidimensional cell growth	5.719360e-3
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	5.719360e-3
GO:0045605	negative regulation of epidermal cell differentiation	5.750589e-3
GO:0007006	mitochondrial membrane organization	5.754295e-3
GO:0007127	meiosis I	5.765177e-3
GO:0000239	pachytene	5.826337e-3
GO:0030149	sphingolipid catabolic process	5.834819e-3
GO:0045581	negative regulation of T cell differentiation	5.856386e-3
GO:0051169	nuclear transport	5.857844e-3
GO:0045017	glycerolipid biosynthetic process	5.878151e-3
GO:0006139	nucleobase-containing compound metabolic process	5.921776e-3
GO:0070228	regulation of lymphocyte apoptosis	5.941676e-3
GO:0007128	meiotic prophase I	5.947612e-3
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	5.983779e-3
GO:0032272	negative regulation of protein polymerization	5.999047e-3
GO:0010157	response to chlorate	6.068971e-3
GO:0043277	apoptotic cell clearance	6.071076e-3
GO:0001836	release of cytochrome c from mitochondria	6.117271e-3
GO:0072553	terminal button organization	6.147279e-3
GO:0034509	centromeric core chromatin assembly	6.147279e-3
GO:0034080	CenH3-containing nucleosome assembly at centromere	6.147279e-3
GO:0042450	arginine biosynthetic process via ornithine	6.166139e-3
GO:0071624	positive regulation of granulocyte chemotaxis	6.166139e-3
GO:0019676	ammonia assimilation cycle	6.166139e-3
GO:0018125	peptidyl-cysteine methylation	6.166139e-3
GO:0021592	fourth ventricle development	6.200842e-3
GO:0019987	negative regulation of anti-apoptosis	6.200842e-3
GO:0090304	nucleic acid metabolic process	6.362330e-3
GO:0045630	positive regulation of T-helper 2 cell differentiation	6.381741e-3
GO:0021861	forebrain radial glial cell differentiation	6.411541e-3
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	6.507290e-3
GO:0021853	cerebral cortex GABAergic interneuron migration	6.729394e-3
GO:0070243	regulation of thymocyte apoptosis	6.814463e-3
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger	6.854286e-3
GO:0007632	visual behavior	6.938374e-3
GO:0045793	positive regulation of cell size	6.940685e-3
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	6.941608e-3
GO:0043366	beta selection	6.941608e-3
GO:0006281	DNA repair	7.128959e-3
GO:0022415	viral reproductive process	7.230299e-3
GO:0051798	positive regulation of hair follicle development	7.256173e-3
GO:0048013	ephrin receptor signaling pathway	7.322229e-3
GO:0046628	positive regulation of insulin receptor signaling pathway	7.366609e-3
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	7.373783e-3
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	7.380547e-3
GO:0043048	dolichyl monophosphate biosynthetic process	7.476687e-3
GO:0060699	regulation of endoribonuclease activity	7.476687e-3
GO:0000056	ribosomal small subunit export from nucleus	7.476687e-3
GO:0018960	4-nitrophenol metabolic process	7.476687e-3
GO:0000055	ribosomal large subunit export from nucleus	7.476687e-3
GO:0045046	protein import into peroxisome membrane	7.590236e-3
GO:0006438	valyl-tRNA aminoacylation	7.590236e-3
GO:0006551	leucine metabolic process	7.590236e-3
GO:0032330	regulation of chondrocyte differentiation	7.822161e-3
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger	7.952831e-3
GO:0032689	negative regulation of interferon-gamma production	8.017275e-3
GO:2000191	regulation of fatty acid transport	8.017275e-3
GO:0045764	positive regulation of cellular amino acid metabolic process	8.075118e-3
GO:0072289	metanephric nephron tubule formation	8.075118e-3
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	8.075118e-3
GO:0006983	ER overload response	8.107613e-3
GO:0034764	positive regulation of transmembrane transport	8.249801e-3
GO:0031034	myosin filament assembly	8.273890e-3
GO:0008380	RNA splicing	8.325875e-3
GO:0002828	regulation of type 2 immune response	8.353966e-3
GO:0048069	eye pigmentation	8.461583e-3
GO:0060244	negative regulation of cell proliferation involved in contact inhibition	8.580410e-3
GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	8.580410e-3
GO:0006807	nitrogen compound metabolic process	8.587404e-3
GO:0045598	regulation of fat cell differentiation	8.729685e-3
GO:0019882	antigen processing and presentation	8.780351e-3
GO:0060561	apoptosis involved in morphogenesis	8.864221e-3
GO:0006171	cAMP biosynthetic process	8.885919e-3
GO:0033205	cell cycle cytokinesis	8.896976e-3
GO:0019395	fatty acid oxidation	8.908421e-3
GO:0002331	pre-B cell allelic exclusion	8.975440e-3
GO:0051938	L-glutamate import	9.151167e-3
GO:0015800	acidic amino acid transport	9.213509e-3
GO:0060458	right lung development	9.243225e-3
GO:0042713	sperm ejaculation	9.243225e-3
GO:0090150	establishment of protein localization in membrane	9.310003e-3
GO:0021678	third ventricle development	9.310003e-3
GO:0035815	positive regulation of renal sodium excretion	9.310003e-3
GO:0003002	regionalization	9.372084e-3
GO:0010759	positive regulation of macrophage chemotaxis	9.418063e-3
GO:0090324	negative regulation of oxidative phosphorylation	9.419051e-3
GO:0010255	glucose mediated signaling pathway	9.419051e-3
GO:0006780	uroporphyrinogen III biosynthetic process	9.419051e-3
GO:0043921	modulation by host of viral transcription	9.461316e-3
GO:0035272	exocrine system development	9.473343e-3
GO:0044319	wound healing, spreading of cells	9.495094e-3
GO:0031507	heterochromatin formation	9.495094e-3
GO:2000639	negative regulation of SREBP-mediated signaling pathway	9.518427e-3
GO:0018343	protein farnesylation	9.518427e-3
GO:2000346	negative regulation of hepatocyte proliferation	9.518427e-3
GO:0042307	positive regulation of protein import into nucleus	9.642673e-3
GO:0017144	drug metabolic process	9.685640e-3
GO:0043967	histone H4 acetylation	9.827499e-3
GO:0048708	astrocyte differentiation	9.905714e-3
GO:0006778	porphyrin-containing compound metabolic process	9.905714e-3
GO:0051298	centrosome duplication	9.952754e-3
GO:0021798	forebrain dorsal/ventral pattern formation	1.011146e-2
GO:0009952	anterior/posterior pattern specification	1.016657e-2
GO:0006573	valine metabolic process	1.030216e-2
GO:0060438	trachea development	1.038767e-2
GO:0043163	cell envelope organization	1.040955e-2
GO:0030449	regulation of complement activation	1.047998e-2
GO:0009314	response to radiation	1.057604e-2
GO:0000281	cytokinesis after mitosis	1.058547e-2
GO:0014829	vascular smooth muscle contraction	1.073667e-2
GO:0002884	negative regulation of hypersensitivity	1.076416e-2
GO:0009309	amine biosynthetic process	1.089755e-2
GO:0033013	tetrapyrrole metabolic process	1.104384e-2
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	1.115257e-2
GO:0030902	hindbrain development	1.122343e-2
GO:0035313	wound healing, spreading of epidermal cells	1.145195e-2
GO:0051016	barbed-end actin filament capping	1.158574e-2
GO:0046718	entry of virus into host cell	1.158574e-2
GO:0060445	branching involved in salivary gland morphogenesis	1.164432e-2
GO:0072676	lymphocyte migration	1.169571e-2
GO:0060486	Clara cell differentiation	1.178203e-2
GO:0016064	immunoglobulin mediated immune response	1.181007e-2
GO:0071478	cellular response to radiation	1.181437e-2
GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway	1.190270e-2
GO:0070925	organelle assembly	1.191182e-2
GO:0010863	positive regulation of phospholipase C activity	1.194103e-2
GO:0009207	purine ribonucleoside triphosphate catabolic process	1.206473e-2
GO:0010332	response to gamma radiation	1.221277e-2
GO:0010763	positive regulation of fibroblast migration	1.230657e-2
GO:0008535	respiratory chain complex IV assembly	1.230964e-2
GO:0060008	Sertoli cell differentiation	1.234879e-2
GO:0009146	purine nucleoside triphosphate catabolic process	1.244635e-2