Novel motif:46

name:	motif46_CGNAGT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0006261	DNA-dependent DNA replication	3.422746e-11
GO:0006281	DNA repair	8.342762e-11
GO:0006283	transcription-coupled nucleotide-excision repair	1.876997e-10
GO:0000718	nucleotide-excision repair, DNA damage removal	2.501984e-9
GO:0071539	protein localization to centrosome	7.086213e-9
GO:0033299	secretion of lysosomal enzymes	1.570866e-8
GO:0050434	positive regulation of viral transcription	6.089444e-8
GO:2000465	regulation of glycogen (starch) synthase activity	7.024303e-8
GO:0021603	cranial nerve formation	1.064574e-7
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	1.567097e-7
GO:2000467	positive regulation of glycogen (starch) synthase activity	1.862963e-7
GO:0030488	tRNA methylation	1.994214e-7
GO:0016032	viral reproduction	3.494463e-7
GO:0046628	positive regulation of insulin receptor signaling pathway	8.648641e-7
GO:0010224	response to UV-B	9.064211e-7
GO:0071460	cellular response to cell-matrix adhesion	9.459706e-7
GO:0009263	deoxyribonucleotide biosynthetic process	9.664895e-7
GO:0006289	nucleotide-excision repair	1.202662e-6
GO:0000216	M/G1 transition of mitotic cell cycle	1.209309e-6
GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	1.627810e-6
GO:0006412	translation	2.099886e-6
GO:0006370	mRNA capping	2.512698e-6
GO:0031573	intra-S DNA damage checkpoint	2.823050e-6
GO:0016071	mRNA metabolic process	2.907459e-6
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	3.082503e-6
GO:0006396	RNA processing	3.398728e-6
GO:0019264	glycine biosynthetic process from serine	4.514862e-6
GO:0070105	positive regulation of interleukin-6-mediated signaling pathway	5.937797e-6
GO:0006545	glycine biosynthetic process	6.088602e-6
GO:0006353	transcription termination, DNA-dependent	6.723153e-6
GO:0006308	DNA catabolic process	7.069869e-6
GO:0006368	transcription elongation from RNA polymerase II promoter	9.108650e-6
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	9.360138e-6
GO:0046782	regulation of viral transcription	1.001348e-5
GO:0035307	positive regulation of protein dephosphorylation	1.038252e-5
GO:0006270	DNA-dependent DNA replication initiation	1.150728e-5
GO:0006414	translational elongation	1.185481e-5
GO:0035306	positive regulation of dephosphorylation	1.198289e-5
GO:0006713	glucocorticoid catabolic process	1.215945e-5
GO:0042946	glucoside transport	1.215945e-5
GO:0014020	primary neural tube formation	1.445999e-5
GO:0032042	mitochondrial DNA metabolic process	1.548202e-5
GO:0006354	transcription elongation, DNA-dependent	2.029639e-5
GO:0035507	regulation of myosin-light-chain-phosphatase activity	2.286369e-5
GO:0009452	RNA capping	2.323839e-5
GO:0000398	nuclear mRNA splicing, via spliceosome	2.733281e-5
GO:0001843	neural tube closure	2.750817e-5
GO:0090031	positive regulation of steroid hormone biosynthetic process	2.787560e-5
GO:0032682	negative regulation of chemokine production	2.958776e-5
GO:0000725	recombinational repair	2.971587e-5
GO:0009186	deoxyribonucleoside diphosphate metabolic process	3.250101e-5
GO:0006119	oxidative phosphorylation	3.307815e-5
GO:0003409	optic cup structural organization	3.791750e-5
GO:0021623	oculomotor nerve formation	3.791750e-5
GO:0003404	optic vesicle morphogenesis	3.791750e-5
GO:0033108	mitochondrial respiratory chain complex assembly	3.854476e-5
GO:0006386	termination of RNA polymerase III transcription	4.074498e-5
GO:0006385	transcription elongation from RNA polymerase III promoter	4.074498e-5
GO:0000724	double-strand break repair via homologous recombination	4.297520e-5
GO:0006117	acetaldehyde metabolic process	4.765058e-5
GO:0033590	response to cobalamin	4.765058e-5
GO:0048790	maintenance of presynaptic active zone structure	4.765058e-5
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	4.765058e-5
GO:0000375	RNA splicing, via transesterification reactions	5.013045e-5
GO:0000084	S phase of mitotic cell cycle	5.067731e-5
GO:0060606	tube closure	5.156669e-5
GO:0015781	pyrimidine nucleotide-sugar transport	5.263381e-5
GO:0035304	regulation of protein dephosphorylation	5.523786e-5
GO:0065002	intracellular protein transmembrane transport	5.744536e-5
GO:0014040	positive regulation of Schwann cell differentiation	6.270961e-5
GO:0006268	DNA unwinding involved in replication	6.540090e-5
GO:0006264	mitochondrial DNA replication	6.649180e-5
GO:0051320	S phase	7.538309e-5
GO:0000022	mitotic spindle elongation	8.031923e-5
GO:0031297	replication fork processing	8.233790e-5
GO:0071281	cellular response to iron ion	8.601860e-5
GO:0034393	positive regulation of smooth muscle cell apoptosis	9.099136e-5
GO:0006349	regulation of gene expression by genetic imprinting	9.526584e-5
GO:0006413	translational initiation	1.006469e-4
GO:0060406	positive regulation of penile erection	1.075991e-4
GO:0031017	exocrine pancreas development	1.083607e-4
GO:0045333	cellular respiration	1.103496e-4
GO:0090232	positive regulation of spindle checkpoint	1.500529e-4
GO:0022027	interkinetic nuclear migration	1.560879e-4
GO:0071638	negative regulation of monocyte chemotactic protein-1 production	1.563801e-4
GO:0070145	mitochondrial asparaginyl-tRNA aminoacylation	1.563801e-4
GO:0030150	protein import into mitochondrial matrix	1.563801e-4
GO:0035726	common myeloid progenitor cell proliferation	1.563801e-4
GO:0035732	nitric oxide storage	1.563801e-4
GO:0051645	Golgi localization	1.587310e-4
GO:0006290	pyrimidine dimer repair	1.631865e-4
GO:0006383	transcription from RNA polymerase III promoter	1.821472e-4
GO:0006458	'de novo' protein folding	1.934628e-4
GO:0048280	vesicle fusion with Golgi apparatus	1.985479e-4
GO:0001705	ectoderm formation	2.054820e-4
GO:0022616	DNA strand elongation	2.178940e-4
GO:0016446	somatic hypermutation of immunoglobulin genes	2.222828e-4
GO:0006450	regulation of translational fidelity	2.322601e-4
GO:0042249	establishment of planar polarity of embryonic epithelium	2.883476e-4
GO:0019323	pentose catabolic process	2.891536e-4
GO:0001830	trophectodermal cell fate commitment	2.891536e-4
GO:0006659	phosphatidylserine biosynthetic process	2.927165e-4
GO:0007020	microtubule nucleation	2.973105e-4
GO:0034126	positive regulation of MyD88-dependent toll-like receptor signaling pathway	2.990815e-4
GO:0006260	DNA replication	3.082848e-4
GO:0006313	transposition, DNA-mediated	3.249270e-4
GO:0015684	ferrous iron transport	3.443521e-4
GO:0042747	circadian sleep/wake cycle, REM sleep	3.557848e-4
GO:0035852	horizontal cell localization	3.557848e-4
GO:0045212	neurotransmitter receptor biosynthetic process	3.557848e-4
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	3.557848e-4
GO:0035846	oviduct epithelium development	3.557848e-4
GO:0032223	negative regulation of synaptic transmission, cholinergic	3.557848e-4
GO:0035849	nephric duct elongation	3.557848e-4
GO:0035502	metanephric ureteric bud development	3.557848e-4
GO:0035847	uterine epithelium development	3.557848e-4
GO:0048532	anatomical structure arrangement	3.761435e-4
GO:0008033	tRNA processing	3.881257e-4
GO:0090342	regulation of cell aging	3.975800e-4
GO:0034453	microtubule anchoring	4.010026e-4
GO:2000773	negative regulation of cellular senescence	4.387104e-4
GO:0043697	cell dedifferentiation	4.387104e-4
GO:0016574	histone ubiquitination	4.796377e-4
GO:0021658	rhombomere 3 morphogenesis	4.813649e-4
GO:0070170	regulation of tooth mineralization	4.937960e-4
GO:0006271	DNA strand elongation involved in DNA replication	4.963878e-4
GO:0009060	aerobic respiration	4.964786e-4
GO:0048524	positive regulation of viral reproduction	5.017994e-4
GO:0032784	regulation of transcription elongation, DNA-dependent	5.055341e-4
GO:0060457	negative regulation of digestive system process	5.109436e-4
GO:0021506	anterior neuropore closure	5.156563e-4
GO:0015789	UDP-N-acetylgalactosamine transport	5.272456e-4
GO:0015787	UDP-glucuronic acid transport	5.272456e-4
GO:0033683	nucleotide-excision repair, DNA incision	5.455653e-4
GO:0042732	D-xylose metabolic process	5.515574e-4
GO:0060005	vestibular reflex	5.517400e-4
GO:0090086	negative regulation of protein deubiquitination	5.599781e-4
GO:0010107	potassium ion import	5.737166e-4
GO:0006310	DNA recombination	6.438993e-4
GO:0051084	'de novo' posttranslational protein folding	6.550724e-4
GO:0043503	skeletal muscle fiber adaptation	6.556454e-4
GO:0043249	erythrocyte maturation	6.608822e-4
GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	7.076184e-4
GO:0051318	G1 phase	7.219733e-4
GO:0003016	respiratory system process	7.880707e-4
GO:0016578	histone deubiquitination	8.104029e-4
GO:0006047	UDP-N-acetylglucosamine metabolic process	8.113592e-4
GO:0051096	positive regulation of helicase activity	8.154402e-4
GO:2000620	positive regulation of histone H4-K16 acetylation	8.249383e-4
GO:2000617	positive regulation of histone H3-K9 acetylation	8.249383e-4
GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	8.249383e-4
GO:0070512	positive regulation of histone H4-K20 methylation	8.249383e-4
GO:0070946	neutrophil mediated killing of gram-positive bacterium	8.572660e-4
GO:0006482	protein demethylation	8.819109e-4
GO:0022613	ribonucleoprotein complex biogenesis	8.977886e-4
GO:0060455	negative regulation of gastric acid secretion	9.129566e-4
GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	9.129566e-4
GO:0006189	'de novo' IMP biosynthetic process	9.129566e-4
GO:0048752	semicircular canal morphogenesis	9.186716e-4
GO:0090344	negative regulation of cell aging	9.279832e-4
GO:0071514	genetic imprinting	9.560719e-4
GO:2000772	regulation of cellular senescence	1.005672e-3
GO:0051299	centrosome separation	1.018489e-3
GO:0000492	box C/D snoRNP assembly	1.018489e-3
GO:0000389	nuclear mRNA 3'-splice site recognition	1.049531e-3
GO:0016188	synaptic vesicle maturation	1.078277e-3
GO:0060405	regulation of penile erection	1.089101e-3
GO:0009436	glyoxylate catabolic process	1.182005e-3
GO:0032074	negative regulation of nuclease activity	1.183841e-3
GO:0050720	interleukin-1 beta biosynthetic process	1.183841e-3
GO:0031627	telomeric loop formation	1.183841e-3
GO:0007274	neuromuscular synaptic transmission	1.221748e-3
GO:0040040	thermosensory behavior	1.230800e-3
GO:0006476	protein deacetylation	1.247827e-3
GO:0000080	G1 phase of mitotic cell cycle	1.248626e-3
GO:0006473	protein acetylation	1.310742e-3
GO:0034470	ncRNA processing	1.336827e-3
GO:0032981	mitochondrial respiratory chain complex I assembly	1.393359e-3
GO:0035871	protein K11-linked deubiquitination	1.396947e-3
GO:0005984	disaccharide metabolic process	1.452045e-3
GO:0006172	ADP biosynthetic process	1.502751e-3
GO:0021796	cerebral cortex regionalization	1.511713e-3
GO:0035601	protein deacylation	1.511963e-3
GO:0031860	telomeric 3' overhang formation	1.544826e-3
GO:0031081	nuclear pore distribution	1.544826e-3
GO:0008052	sensory organ boundary specification	1.553947e-3
GO:0000082	G1/S transition of mitotic cell cycle	1.633237e-3
GO:0051497	negative regulation of stress fiber assembly	1.639516e-3
GO:0006853	carnitine shuttle	1.639516e-3
GO:0006369	termination of RNA polymerase II transcription	1.667685e-3
GO:0071843	cellular component biogenesis at cellular level	1.681722e-3
GO:0045176	apical protein localization	1.699434e-3
GO:0018202	peptidyl-histidine modification	1.699826e-3
GO:0042776	mitochondrial ATP synthesis coupled proton transport	1.701491e-3
GO:0019087	transformation of host cell by virus	1.720058e-3
GO:0090231	regulation of spindle checkpoint	1.751944e-3
GO:0045655	regulation of monocyte differentiation	1.751944e-3
GO:0046626	regulation of insulin receptor signaling pathway	1.805830e-3
GO:0043415	positive regulation of skeletal muscle tissue regeneration	1.813953e-3
GO:0032201	telomere maintenance via semi-conservative replication	1.823652e-3
GO:0051131	chaperone-mediated protein complex assembly	1.861457e-3
GO:0019303	D-ribose catabolic process	1.878592e-3
GO:0006400	tRNA modification	1.899082e-3
GO:0022618	ribonucleoprotein complex assembly	1.913120e-3
GO:0007184	SMAD protein import into nucleus	1.938836e-3
GO:0071826	ribonucleoprotein complex subunit organization	1.954787e-3
GO:0071557	histone H3-K27 demethylation	1.967982e-3
GO:0035574	histone H4-K20 demethylation	1.967982e-3
GO:0090085	regulation of protein deubiquitination	1.992436e-3
GO:0048205	COPI coating of Golgi vesicle	2.006347e-3
GO:0008380	RNA splicing	2.049161e-3
GO:0042254	ribosome biogenesis	2.064785e-3
GO:0006475	internal protein amino acid acetylation	2.135367e-3
GO:0006397	mRNA processing	2.135935e-3
GO:0000387	spliceosomal snRNP assembly	2.190179e-3
GO:0042775	mitochondrial ATP synthesis coupled electron transport	2.250896e-3
GO:0035845	photoreceptor cell outer segment organization	2.281824e-3
GO:0035305	negative regulation of dephosphorylation	2.344914e-3
GO:0060947	cardiac vascular smooth muscle cell differentiation	2.348861e-3
GO:0015788	UDP-N-acetylglucosamine transport	2.447104e-3
GO:0051083	'de novo' cotranslational protein folding	2.447104e-3
GO:0006348	chromatin silencing at telomere	2.447104e-3
GO:0009304	tRNA transcription	2.477991e-3
GO:0042637	catagen	2.549241e-3
GO:0016573	histone acetylation	2.716190e-3
GO:0060914	heart formation	2.746150e-3
GO:0015780	nucleotide-sugar transport	2.832283e-3
GO:0032581	ER-dependent peroxisome organization	2.947851e-3
GO:0042255	ribosome assembly	2.982821e-3
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	3.128001e-3
GO:0009265	2'-deoxyribonucleotide biosynthetic process	3.227843e-3
GO:0072111	cell proliferation involved in kidney development	3.298760e-3
GO:0045657	positive regulation of monocyte differentiation	3.299738e-3
GO:0006359	regulation of transcription from RNA polymerase III promoter	3.397823e-3
GO:0048194	Golgi vesicle budding	3.472283e-3
GO:0060381	positive regulation of single-stranded telomeric DNA binding	3.567729e-3
GO:0022904	respiratory electron transport chain	3.701371e-3
GO:0034551	mitochondrial respiratory chain complex III assembly	3.736440e-3
GO:0045128	negative regulation of reciprocal meiotic recombination	3.736440e-3
GO:0006311	meiotic gene conversion	3.736440e-3
GO:0051549	positive regulation of keratinocyte migration	3.744152e-3
GO:0043543	protein acylation	3.749026e-3
GO:0070103	regulation of interleukin-6-mediated signaling pathway	3.807580e-3
GO:0045014	negative regulation of transcription by glucose	3.846432e-3
GO:0009133	nucleoside diphosphate biosynthetic process	3.854081e-3
GO:0021557	oculomotor nerve development	3.884685e-3
GO:0009262	deoxyribonucleotide metabolic process	3.923992e-3
GO:0071934	thiamine transmembrane transport	4.041840e-3
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	4.085180e-3
GO:0006099	tricarboxylic acid cycle	4.088957e-3
GO:0019532	oxalate transport	4.221305e-3
GO:0060575	intestinal epithelial cell differentiation	4.227954e-3
GO:0006564	L-serine biosynthetic process	4.333506e-3
GO:0019388	galactose catabolic process	4.411908e-3
GO:0080009	mRNA methylation	4.517430e-3
GO:0042450	arginine biosynthetic process via ornithine	4.517430e-3
GO:0014908	myotube differentiation involved in skeletal muscle regeneration	4.517430e-3
GO:0008049	male courtship behavior	4.517430e-3
GO:0006012	galactose metabolic process	4.522219e-3
GO:0006415	translational termination	4.630686e-3
GO:0006302	double-strand break repair	4.650328e-3
GO:0009202	deoxyribonucleoside triphosphate biosynthetic process	4.659410e-3
GO:0043309	regulation of eosinophil degranulation	4.659410e-3
GO:0010544	negative regulation of platelet activation	4.749395e-3
GO:0009153	purine deoxyribonucleotide biosynthetic process	4.813342e-3
GO:0002069	columnar/cuboidal epithelial cell maturation	4.813342e-3
GO:0046356	acetyl-CoA catabolic process	4.844235e-3
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	4.908131e-3
GO:0035566	regulation of metanephros size	4.908131e-3
GO:0008340	determination of adult lifespan	5.010169e-3
GO:0010923	negative regulation of phosphatase activity	5.136631e-3
GO:2000303	regulation of ceramide biosynthetic process	5.215879e-3
GO:0060574	intestinal epithelial cell maturation	5.239535e-3
GO:0060807	regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification	5.239535e-3
GO:0030421	defecation	5.239535e-3
GO:0035356	cellular triglyceride homeostasis	5.239535e-3
GO:0003142	cardiogenic plate morphogenesis	5.239535e-3
GO:0030952	establishment or maintenance of cytoskeleton polarity	5.305889e-3
GO:0006108	malate metabolic process	5.407565e-3
GO:0031848	protection from non-homologous end joining at telomere	5.489106e-3
GO:0070375	BMK cascade	5.489106e-3
GO:0060033	anatomical structure regression	5.549681e-3
GO:0035026	leading edge cell differentiation	5.673414e-3
GO:0009301	snRNA transcription	5.673414e-3
GO:0060301	positive regulation of cytokine activity	5.781427e-3
GO:0000710	meiotic mismatch repair	5.781427e-3
GO:2000300	regulation of synaptic vesicle exocytosis	5.789396e-3
GO:0048075	positive regulation of eye pigmentation	5.815257e-3
GO:0042481	regulation of odontogenesis	5.830404e-3
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	5.908175e-3
GO:0032515	negative regulation of phosphoprotein phosphatase activity	5.979241e-3
GO:0006892	post-Golgi vesicle-mediated transport	5.987388e-3
GO:0006513	protein monoubiquitination	6.020223e-3
GO:0006974	response to DNA damage stimulus	6.054735e-3
GO:0051573	negative regulation of histone H3-K9 methylation	6.060695e-3
GO:0046730	induction of host immune response by virus	6.143932e-3
GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	6.143932e-3
GO:0090084	negative regulation of inclusion body assembly	6.179702e-3
GO:0032816	positive regulation of natural killer cell activation	6.205665e-3
GO:0032785	negative regulation of transcription elongation, DNA-dependent	6.322883e-3
GO:0051292	nuclear pore complex assembly	6.330536e-3
GO:0033131	regulation of glucokinase activity	6.382783e-3
GO:0021783	preganglionic parasympathetic nervous system development	6.403284e-3
GO:0043111	replication fork arrest	6.535690e-3
GO:0042840	D-glucuronate catabolic process	6.535690e-3
GO:0051684	maintenance of Golgi location	6.535690e-3
GO:0060921	sinoatrial node cell differentiation	6.535690e-3
GO:2000340	positive regulation of chemokine (C-X-C motif) ligand 1 production	6.535690e-3
GO:0060975	cardioblast migration to the midline involved in heart field formation	6.535690e-3
GO:0042664	negative regulation of endodermal cell fate specification	6.535690e-3
GO:0003259	cardioblast anterior-lateral migration	6.535690e-3
GO:0003210	cardiac atrium formation	6.535690e-3
GO:0035665	TIRAP-dependent toll-like receptor 4 signaling pathway	6.535690e-3
GO:0003241	growth involved in heart morphogenesis	6.535690e-3
GO:0003236	sinus venosus morphogenesis	6.535690e-3
GO:0032738	positive regulation of interleukin-15 production	6.535690e-3
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	6.535690e-3
GO:0009236	cobalamin biosynthetic process	6.535690e-3
GO:0070935	3'-UTR-mediated mRNA stabilization	6.584620e-3
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	6.657844e-3
GO:0021666	rhombomere 5 formation	6.686732e-3
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	6.686732e-3
GO:0045090	retroviral genome replication	6.686732e-3
GO:0021660	rhombomere 3 formation	6.686732e-3
GO:0006175	dATP biosynthetic process	6.686732e-3
GO:0006478	peptidyl-tyrosine sulfation	6.686732e-3
GO:0021599	abducens nerve formation	6.714472e-3
GO:0007634	optokinetic behavior	6.714472e-3
GO:0051534	negative regulation of NFAT protein import into nucleus	6.773632e-3
GO:0048627	myoblast development	6.829664e-3
GO:0031936	negative regulation of chromatin silencing	6.874454e-3
GO:0015696	ammonium transport	7.081785e-3
GO:0051546	keratinocyte migration	7.174723e-3
GO:0018393	internal peptidyl-lysine acetylation	7.208216e-3
GO:0033132	negative regulation of glucokinase activity	7.303975e-3
GO:0006398	histone mRNA 3'-end processing	7.303975e-3
GO:0021591	ventricular system development	7.308165e-3
GO:0021569	rhombomere 3 development	7.310885e-3
GO:0051321	meiotic cell cycle	7.374728e-3
GO:0072300	positive regulation of metanephric glomerulus development	7.383891e-3
GO:0032637	interleukin-8 production	7.383891e-3
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	7.472737e-3
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	7.472737e-3
GO:0006548	histidine catabolic process	7.478702e-3
GO:0043241	protein complex disassembly	7.519574e-3
GO:0002041	intussusceptive angiogenesis	7.684057e-3
GO:0090104	pancreatic E cell differentiation	7.826931e-3
GO:0034509	centromeric core chromatin assembly	7.826931e-3
GO:0003311	pancreatic D cell differentiation	7.826931e-3
GO:0005998	xylulose catabolic process	7.826931e-3
GO:0021559	trigeminal nerve development	7.883302e-3
GO:0006044	N-acetylglucosamine metabolic process	7.910443e-3
GO:0018394	peptidyl-lysine acetylation	8.097685e-3
GO:0048102	autophagic cell death	8.499914e-3
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	8.652270e-3
GO:0006999	nuclear pore organization	8.652270e-3
GO:0042797	tRNA transcription from RNA polymerase III promoter	8.655129e-3
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	8.655129e-3
GO:2000111	positive regulation of macrophage apoptosis	8.730425e-3
GO:0014038	regulation of Schwann cell differentiation	8.764805e-3
GO:0048793	pronephros development	9.305625e-3
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	9.341374e-3
GO:0046655	folic acid metabolic process	9.343309e-3
GO:0009070	serine family amino acid biosynthetic process	9.468738e-3
GO:0007126	meiosis	9.724216e-3
GO:0050975	sensory perception of touch	9.838383e-3
GO:0016180	snRNA processing	9.873723e-3
GO:0071169	establishment of protein localization to chromatin	1.007647e-2
GO:0015919	peroxisomal membrane transport	1.007647e-2
GO:0006844	acyl carnitine transport	1.007647e-2
GO:0006756	AMP phosphorylation	1.007647e-2
GO:0006356	regulation of transcription from RNA polymerase I promoter	1.014933e-2
GO:0001302	replicative cell aging	1.014933e-2
GO:0003406	retinal pigment epithelium development	1.021641e-2
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	1.025423e-2
GO:0031129	inductive cell-cell signaling	1.025732e-2
GO:0090305	nucleic acid phosphodiester bond hydrolysis	1.028542e-2
GO:0070172	positive regulation of tooth mineralization	1.035518e-2
GO:0070366	regulation of hepatocyte differentiation	1.038127e-2
GO:0046502	uroporphyrinogen III metabolic process	1.038127e-2
GO:0009294	DNA mediated transformation	1.038127e-2
GO:0035308	negative regulation of protein dephosphorylation	1.048934e-2
GO:0060968	regulation of gene silencing	1.049393e-2
GO:0032230	positive regulation of synaptic transmission, GABAergic	1.050632e-2
GO:0006405	RNA export from nucleus	1.071199e-2
GO:0006298	mismatch repair	1.085312e-2
GO:0006901	vesicle coating	1.110836e-2
GO:0021670	lateral ventricle development	1.115365e-2
GO:0051492	regulation of stress fiber assembly	1.122685e-2
GO:0051882	mitochondrial depolarization	1.123657e-2
GO:0015822	ornithine transport	1.128648e-2
GO:2000304	positive regulation of ceramide biosynthetic process	1.131413e-2
GO:0006544	glycine metabolic process	1.141978e-2
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	1.150888e-2
GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	1.168222e-2
GO:0016090	prenol metabolic process	1.175109e-2
GO:0009650	UV protection	1.182907e-2
GO:0035721	intraflagellar retrograde transport	1.198894e-2
GO:0048105	establishment of body hair planar orientation	1.200349e-2
GO:0060489	planar dichotomous subdivision of terminal units involved in lung branching morphogenesis	1.200349e-2
GO:0060490	lateral sprouting involved in lung morphogenesis	1.200349e-2
GO:0060488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis	1.200349e-2
GO:0033484	nitric oxide homeostasis	1.215869e-2
GO:0090331	negative regulation of platelet aggregation	1.217012e-2
GO:0061110	dense core granule biogenesis	1.217012e-2
GO:2000971	negative regulation of detection of glucose	1.217012e-2
GO:2000976	regulation of transcription from RNA polymerase II promoter involved in detection of glucose	1.217012e-2
GO:0061108	seminal vesicle epithelium development	1.217012e-2
GO:0002115	store-operated calcium entry	1.217012e-2
GO:0000433	negative regulation of transcription from RNA polymerase II promoter by glucose	1.217012e-2
GO:0042628	mating plug formation	1.217012e-2
GO:0061034	olfactory bulb mitral cell layer development	1.228856e-2
GO:0051095	regulation of helicase activity	1.235135e-2
GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein	1.235871e-2
GO:0060576	intestinal epithelial cell development	1.237725e-2
GO:0060969	negative regulation of gene silencing	1.250450e-2
GO:0021602	cranial nerve morphogenesis	1.276782e-2
GO:0009132	nucleoside diphosphate metabolic process	1.324947e-2
GO:0009313	oligosaccharide catabolic process	1.330452e-2
GO:0006361	transcription initiation from RNA polymerase I promoter	1.341697e-2
GO:0035583	negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta	1.378462e-2
GO:0051414	response to cortisol stimulus	1.391677e-2
GO:0048619	embryonic hindgut morphogenesis	1.408180e-2
GO:0010587	miRNA catabolic process	1.408365e-2
GO:0017121	phospholipid scrambling	1.419106e-2
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	1.419679e-2
GO:0001510	RNA methylation	1.419982e-2
GO:0035166	post-embryonic hemopoiesis	1.420713e-2
GO:0030032	lamellipodium assembly	1.423105e-2
GO:0060040	retinal bipolar neuron differentiation	1.442967e-2
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	1.445236e-2
GO:0072177	mesonephric duct development	1.458494e-2
GO:0033092	positive regulation of immature T cell proliferation in thymus	1.458494e-2
GO:0060300	regulation of cytokine activity	1.463240e-2
GO:0000076	DNA replication checkpoint	1.463240e-2
GO:0060713	labyrinthine layer morphogenesis	1.473077e-2
GO:0042473	outer ear morphogenesis	1.489977e-2
GO:0010936	negative regulation of macrophage cytokine production	1.489977e-2
GO:0043624	cellular protein complex disassembly	1.490772e-2
GO:0032232	negative regulation of actin filament bundle assembly	1.509166e-2
GO:0006547	histidine metabolic process	1.531545e-2
GO:0031935	regulation of chromatin silencing	1.534808e-2
GO:0021575	hindbrain morphogenesis	1.548146e-2
GO:0032392	DNA geometric change	1.550499e-2
GO:0010520	regulation of reciprocal meiotic recombination	1.580153e-2
GO:0009443	pyridoxal 5'-phosphate salvage	1.580153e-2
GO:0032289	central nervous system myelin formation	1.601085e-2
GO:0003310	pancreatic A cell differentiation	1.615470e-2
GO:0048199	vesicle targeting, to, from or within Golgi	1.635044e-2
GO:0032200	telomere organization	1.648604e-2
GO:0015842	synaptic vesicle amine transport	1.648855e-2
GO:0000066	mitochondrial ornithine transport	1.648855e-2
GO:0051102	DNA ligation involved in DNA recombination	1.651742e-2
GO:2000009	negative regulation of protein localization at cell surface	1.651742e-2
GO:0043456	regulation of pentose-phosphate shunt	1.651742e-2
GO:0018192	enzyme active site formation via L-cysteine persulfide	1.651742e-2
GO:0060459	left lung development	1.689463e-2
GO:0033373	maintenance of protease location in mast cell secretory granule	1.689463e-2
GO:0033382	maintenance of granzyme B location in T cell secretory granule	1.689463e-2
GO:0035020	regulation of Rac protein signal transduction	1.702280e-2
GO:0060913	cardiac cell fate determination	1.714147e-2
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	1.717880e-2
GO:0045351	type I interferon biosynthetic process	1.731608e-2
GO:2000109	regulation of macrophage apoptosis	1.740984e-2
GO:0010498	proteasomal protein catabolic process	1.749653e-2
GO:0071569	protein ufmylation	1.825846e-2
GO:0010739	positive regulation of protein kinase A signaling cascade	1.827896e-2
GO:0016577	histone demethylation	1.839970e-2
GO:0090103	cochlea morphogenesis	1.842190e-2
GO:0019079	viral genome replication	1.846853e-2
GO:0006297	nucleotide-excision repair, DNA gap filling	1.847225e-2
GO:0048242	epinephrine secretion	1.869957e-2
GO:0009785	blue light signaling pathway	1.869957e-2
GO:0070535	histone H2A K63-linked ubiquitination	1.873670e-2
GO:0006406	mRNA export from nucleus	1.880533e-2
GO:0006312	mitotic recombination	1.896610e-2
GO:0090042	tubulin deacetylation	1.898725e-2
GO:0070846	Hsp90 deacetylation	1.898725e-2
GO:0006272	leading strand elongation	1.898725e-2
GO:0060209	estrus	1.898725e-2
GO:0000715	nucleotide-excision repair, DNA damage recognition	1.908275e-2
GO:0090251	protein localization involved in establishment of planar polarity	1.923838e-2
GO:0060837	blood vessel endothelial cell differentiation	1.923838e-2
GO:0051325	interphase	1.938553e-2
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.969013e-2
GO:0032288	myelin assembly	1.982858e-2
GO:0001778	plasma membrane repair	2.001947e-2
GO:0015074	DNA integration	2.030332e-2
GO:0009109	coenzyme catabolic process	2.034309e-2
GO:0016559	peroxisome fission	2.044009e-2
GO:0005993	trehalose catabolic process	2.044009e-2
GO:0090193	positive regulation of glomerulus development	2.052583e-2
GO:0010807	regulation of synaptic vesicle priming	2.055903e-2
GO:0048298	positive regulation of isotype switching to IgA isotypes	2.082355e-2
GO:0001710	mesodermal cell fate commitment	2.129362e-2
GO:0070127	tRNA aminoacylation for mitochondrial protein translation	2.177810e-2
GO:0006670	sphingosine metabolic process	2.207881e-2
GO:0048203	vesicle targeting, trans-Golgi to endosome	2.212343e-2
GO:2000597	positive regulation of optic nerve formation	2.212343e-2
GO:0034633	retinol transport	2.212343e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0034660	ncRNA metabolic process	1.760748e-13
GO:0034470	ncRNA processing	1.721635e-11
GO:0043558	regulation of translational initiation in response to stress	8.022370e-10
GO:0006412	translation	4.814873e-9
GO:0035306	positive regulation of dephosphorylation	9.087238e-9
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	2.045558e-8
GO:0035307	positive regulation of protein dephosphorylation	2.111046e-8
GO:0043555	regulation of translation in response to stress	3.233639e-8
GO:0006399	tRNA metabolic process	2.509643e-7
GO:0050823	peptide antigen stabilization	2.670797e-7
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	2.670797e-7
GO:0008033	tRNA processing	4.640853e-7
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	5.029899e-7
GO:0032922	circadian regulation of gene expression	5.759897e-7
GO:0006396	RNA processing	1.153846e-6
GO:0051301	cell division	1.226822e-6
GO:0043243	positive regulation of protein complex disassembly	1.837924e-6
GO:0016180	snRNA processing	1.944588e-6
GO:0016073	snRNA metabolic process	2.399236e-6
GO:0000279	M phase	3.376694e-6
GO:0006680	glucosylceramide catabolic process	4.318542e-6
GO:0045626	negative regulation of T-helper 1 cell differentiation	4.709099e-6
GO:2000383	regulation of ectoderm development	5.310049e-6
GO:0021681	cerebellar granular layer development	6.644359e-6
GO:0090086	negative regulation of protein deubiquitination	1.253739e-5
GO:0006413	translational initiation	1.706419e-5
GO:0002678	positive regulation of chronic inflammatory response	2.113837e-5
GO:0008053	mitochondrial fusion	2.198414e-5
GO:0044260	cellular macromolecule metabolic process	2.459751e-5
GO:0090084	negative regulation of inclusion body assembly	2.930023e-5
GO:2000384	negative regulation of ectoderm development	3.001681e-5
GO:0010616	negative regulation of cardiac muscle adaptation	3.472804e-5
GO:0055119	relaxation of cardiac muscle	3.500357e-5
GO:0010950	positive regulation of endopeptidase activity	3.500357e-5
GO:0032515	negative regulation of phosphoprotein phosphatase activity	3.822219e-5
GO:0021707	cerebellar granule cell differentiation	3.998777e-5
GO:0060948	cardiac vascular smooth muscle cell development	4.475962e-5
GO:0046069	cGMP catabolic process	5.179462e-5
GO:0071267	L-methionine salvage	5.342427e-5
GO:0008616	queuosine biosynthetic process	5.689350e-5
GO:0021683	cerebellar granular layer morphogenesis	5.839992e-5
GO:0032467	positive regulation of cytokinesis	6.674181e-5
GO:0019509	L-methionine salvage from methylthioadenosine	7.858245e-5
GO:0051901	positive regulation of mitochondrial depolarization	8.327699e-5
GO:0045750	positive regulation of S phase of mitotic cell cycle	8.327699e-5
GO:0048284	organelle fusion	8.421010e-5
GO:0032218	riboflavin transport	8.939492e-5
GO:0090140	regulation of mitochondrial fission	9.103939e-5
GO:0008617	guanosine metabolic process	9.103939e-5
GO:0060124	positive regulation of growth hormone secretion	9.649696e-5
GO:0006625	protein targeting to peroxisome	1.091889e-4
GO:0035304	regulation of protein dephosphorylation	1.165191e-4
GO:0032465	regulation of cytokinesis	1.216119e-4
GO:0007067	mitosis	1.222183e-4
GO:0010833	telomere maintenance via telomere lengthening	1.256494e-4
GO:0000059	protein import into nucleus, docking	1.323505e-4
GO:0034587	piRNA metabolic process	1.330810e-4
GO:0090085	regulation of protein deubiquitination	1.420487e-4
GO:0006430	lysyl-tRNA aminoacylation	1.665348e-4
GO:0048239	negative regulation of DNA recombination at telomere	1.665348e-4
GO:2000296	negative regulation of hydrogen peroxide catabolic process	1.665348e-4
GO:0033617	mitochondrial respiratory chain complex IV assembly	1.665348e-4
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	1.670745e-4
GO:0032516	positive regulation of phosphoprotein phosphatase activity	1.671400e-4
GO:0046986	negative regulation of hemoglobin biosynthetic process	1.738038e-4
GO:0015969	guanosine tetraphosphate metabolic process	1.738038e-4
GO:0070265	necrotic cell death	1.739870e-4
GO:0000087	M phase of mitotic cell cycle	2.285384e-4
GO:0090231	regulation of spindle checkpoint	2.637114e-4
GO:0055118	negative regulation of cardiac muscle contraction	2.670771e-4
GO:0007049	cell cycle	2.704263e-4
GO:0051220	cytoplasmic sequestering of protein	2.718801e-4
GO:0030163	protein catabolic process	2.720501e-4
GO:0010467	gene expression	2.742873e-4
GO:0018023	peptidyl-lysine trimethylation	2.812111e-4
GO:0006354	transcription elongation, DNA-dependent	2.831771e-4
GO:0090141	positive regulation of mitochondrial fission	3.046086e-4
GO:0006259	DNA metabolic process	3.167217e-4
GO:0006414	translational elongation	3.250830e-4
GO:0090304	nucleic acid metabolic process	3.654342e-4
GO:0051135	positive regulation of NK T cell activation	4.161614e-4
GO:0048285	organelle fission	4.207498e-4
GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development	4.545834e-4
GO:0002030	inhibitory G-protein coupled receptor phosphorylation	4.545834e-4
GO:0030719	P granule organization	4.545834e-4
GO:0031129	inductive cell-cell signaling	4.982684e-4
GO:0032057	negative regulation of translational initiation in response to stress	4.982684e-4
GO:0008611	ether lipid biosynthetic process	4.982684e-4
GO:0019285	glycine betaine biosynthetic process from choline	5.098476e-4
GO:0070935	3'-UTR-mediated mRNA stabilization	5.419078e-4
GO:0006352	transcription initiation, DNA-dependent	5.570845e-4
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	5.699003e-4
GO:0000379	tRNA-type intron splice site recognition and cleavage	5.910311e-4
GO:0014745	negative regulation of muscle adaptation	6.056767e-4
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	6.108777e-4
GO:0021578	hindbrain maturation	6.976103e-4
GO:0016558	protein import into peroxisome matrix	7.221996e-4
GO:0007076	mitotic chromosome condensation	7.330632e-4
GO:0021750	vestibular nucleus development	7.432719e-4
GO:0021679	cerebellar molecular layer development	7.432719e-4
GO:0021590	cerebellum maturation	7.432719e-4
GO:0016078	tRNA catabolic process	8.530840e-4
GO:0001682	tRNA 5'-leader removal	8.530840e-4
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	8.715810e-4
GO:0006366	transcription from RNA polymerase II promoter	8.858876e-4
GO:0006919	activation of caspase activity	8.867637e-4
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	8.941521e-4
GO:0035095	behavioral response to nicotine	8.980100e-4
GO:0008634	negative regulation of survival gene product expression	9.063042e-4
GO:0097084	vascular smooth muscle cell development	9.107503e-4
GO:0021933	radial glia guided migration of cerebellar granule cell	9.489407e-4
GO:0008380	RNA splicing	9.570905e-4
GO:0000209	protein polyubiquitination	9.738010e-4
GO:0048255	mRNA stabilization	9.987309e-4
GO:0006289	nucleotide-excision repair	1.038762e-3
GO:0060458	right lung development	1.074693e-3
GO:0006172	ADP biosynthetic process	1.074693e-3
GO:0006094	gluconeogenesis	1.219440e-3
GO:2000381	negative regulation of mesoderm development	1.269283e-3
GO:0010991	negative regulation of SMAD protein complex assembly	1.269283e-3
GO:0032055	negative regulation of translation in response to stress	1.299745e-3
GO:0015991	ATP hydrolysis coupled proton transport	1.307673e-3
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	1.308498e-3
GO:0060282	positive regulation of oocyte development	1.376207e-3
GO:0060281	regulation of oocyte development	1.376207e-3
GO:0046479	glycosphingolipid catabolic process	1.428614e-3
GO:0006578	betaine biosynthetic process	1.428614e-3
GO:0008535	respiratory chain complex IV assembly	1.454008e-3
GO:0007099	centriole replication	1.459517e-3
GO:0001522	pseudouridine synthesis	1.461938e-3
GO:0033108	mitochondrial respiratory chain complex assembly	1.497957e-3
GO:0042851	L-alanine metabolic process	1.508392e-3
GO:0006888	ER to Golgi vesicle-mediated transport	1.532535e-3
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	1.562701e-3
GO:0046477	glycosylceramide catabolic process	1.629131e-3
GO:0070198	protein localization to chromosome, telomeric region	1.629131e-3
GO:0042994	cytoplasmic sequestering of transcription factor	1.714299e-3
GO:0006984	ER-nucleus signaling pathway	1.741869e-3
GO:0008063	Toll signaling pathway	1.783674e-3
GO:0006264	mitochondrial DNA replication	1.807248e-3
GO:0032933	SREBP-mediated signaling pathway	1.841443e-3
GO:0006657	CDP-choline pathway	1.863969e-3
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.867170e-3
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	1.867170e-3
GO:0032784	regulation of transcription elongation, DNA-dependent	1.918913e-3
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	1.928033e-3
GO:0050883	musculoskeletal movement, spinal reflex action	2.040934e-3
GO:0046639	negative regulation of alpha-beta T cell differentiation	2.058961e-3
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	2.090571e-3
GO:0043094	cellular metabolic compound salvage	2.094102e-3
GO:0007140	male meiosis	2.216494e-3
GO:0032785	negative regulation of transcription elongation, DNA-dependent	2.238524e-3
GO:0006266	DNA ligation	2.320339e-3
GO:0007028	cytoplasm organization	2.340578e-3
GO:0006863	purine base transport	2.370490e-3
GO:0071103	DNA conformation change	2.533694e-3
GO:0035865	cellular response to potassium ion	2.551285e-3
GO:0043181	vacuolar sequestering	2.551285e-3
GO:0034651	cortisol biosynthetic process	2.551285e-3
GO:0006427	histidyl-tRNA aminoacylation	2.551285e-3
GO:0006409	tRNA export from nucleus	2.551285e-3
GO:0015966	diadenosine tetraphosphate biosynthetic process	2.551285e-3
GO:0034502	protein localization to chromosome	2.577724e-3
GO:0031065	positive regulation of histone deacetylation	2.729839e-3
GO:0019319	hexose biosynthetic process	2.754210e-3
GO:0010457	centriole-centriole cohesion	2.758672e-3
GO:0016081	synaptic vesicle docking involved in exocytosis	2.789072e-3
GO:0014051	gamma-aminobutyric acid secretion	2.839218e-3
GO:0000733	DNA strand renaturation	3.008496e-3
GO:0045964	positive regulation of dopamine metabolic process	3.020724e-3
GO:0032226	positive regulation of synaptic transmission, dopaminergic	3.020724e-3
GO:0042254	ribosome biogenesis	3.113760e-3
GO:0046129	purine ribonucleoside biosynthetic process	3.161039e-3
GO:0045919	positive regulation of cytolysis	3.210242e-3
GO:0032342	aldosterone biosynthetic process	3.263394e-3
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	3.263394e-3
GO:0003127	detection of nodal flow	3.263394e-3
GO:0009589	detection of UV	3.263394e-3
GO:0051298	centrosome duplication	3.390542e-3
GO:0031848	protection from non-homologous end joining at telomere	3.397256e-3
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	3.397256e-3
GO:0002175	protein localization to paranode region of axon	3.477048e-3
GO:0006577	betaine metabolic process	3.635166e-3
GO:0060123	regulation of growth hormone secretion	3.643853e-3
GO:0023021	termination of signal transduction	3.671037e-3
GO:2000117	negative regulation of cysteine-type endopeptidase activity	3.967708e-3
GO:0007228	positive regulation of hh target transcription factor activity	3.967708e-3
GO:0090312	positive regulation of protein deacetylation	4.055465e-3
GO:0030644	cellular chloride ion homeostasis	4.067582e-3
GO:0060266	negative regulation of respiratory burst involved in inflammatory response	4.089689e-3
GO:0006540	glutamate decarboxylation to succinate	4.089689e-3
GO:0034214	protein hexamerization	4.379842e-3
GO:0001778	plasma membrane repair	4.406880e-3
GO:0006368	transcription elongation from RNA polymerase II promoter	4.423254e-3
GO:0002483	antigen processing and presentation of endogenous peptide antigen	4.423254e-3
GO:0031497	chromatin assembly	4.433041e-3
GO:0006778	porphyrin-containing compound metabolic process	4.501586e-3
GO:0022402	cell cycle process	4.633007e-3
GO:0021697	cerebellar cortex formation	4.635557e-3
GO:0006555	methionine metabolic process	4.637736e-3
GO:0000002	mitochondrial genome maintenance	4.637736e-3
GO:0065004	protein-DNA complex assembly	4.793462e-3
GO:0060459	left lung development	4.814505e-3
GO:0003065	positive regulation of heart rate by epinephrine	4.817982e-3
GO:2000062	negative regulation of ureter smooth muscle cell differentiation	4.834011e-3
GO:0080125	multicellular structure septum development	4.834011e-3
GO:2000358	positive regulation of kidney smooth muscle cell differentiation	4.834011e-3
GO:0060783	mesenchymal smoothened signaling pathway involved in prostate gland development	4.834011e-3
GO:2000357	negative regulation of kidney smooth muscle cell differentiation	4.834011e-3
GO:2000063	positive regulation of ureter smooth muscle cell differentiation	4.834011e-3
GO:0035562	negative regulation of chromatin binding	4.834011e-3
GO:0000415	negative regulation of histone H3-K36 methylation	4.834011e-3
GO:0007502	digestive tract mesoderm development	4.834011e-3
GO:0014858	positive regulation of skeletal muscle cell proliferation	4.834011e-3
GO:0046534	positive regulation of photoreceptor cell differentiation	4.834011e-3
GO:0060782	regulation of mesenchymal cell proliferation involved in prostate gland development	4.834011e-3
GO:0000723	telomere maintenance	4.860805e-3
GO:0070842	aggresome assembly	4.917237e-3
GO:0046984	regulation of hemoglobin biosynthetic process	4.917237e-3
GO:0016539	intein-mediated protein splicing	4.917237e-3
GO:0043488	regulation of mRNA stability	5.063241e-3
GO:0000819	sister chromatid segregation	5.080578e-3
GO:0045780	positive regulation of bone resorption	5.121949e-3
GO:0000079	regulation of cyclin-dependent protein kinase activity	5.199657e-3
GO:0032200	telomere organization	5.223860e-3
GO:0042335	cuticle development	5.406991e-3
GO:0043048	dolichyl monophosphate biosynthetic process	5.406991e-3
GO:0071279	cellular response to cobalt ion	5.406991e-3
GO:0035364	thymine transport	5.406991e-3
GO:0035344	hypoxanthine transport	5.406991e-3
GO:0015853	adenine transport	5.406991e-3
GO:0015854	guanine transport	5.406991e-3
GO:0010637	negative regulation of mitochondrial fusion	5.406991e-3
GO:0045623	negative regulation of T-helper cell differentiation	5.451832e-3
GO:0003322	pancreatic A cell development	5.511187e-3
GO:0021905	forebrain-midbrain boundary formation	5.511187e-3
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	5.511187e-3
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	5.511187e-3
GO:0032981	mitochondrial respiratory chain complex I assembly	5.552802e-3
GO:0030320	cellular monovalent inorganic anion homeostasis	5.552802e-3
GO:0006308	DNA catabolic process	5.561747e-3
GO:0006260	DNA replication	5.620172e-3
GO:0032446	protein modification by small protein conjugation	5.667141e-3
GO:0010719	negative regulation of epithelial to mesenchymal transition	5.815247e-3
GO:0072355	histone H3-T3 phosphorylation	5.818374e-3
GO:0090042	tubulin deacetylation	5.818374e-3
GO:0070846	Hsp90 deacetylation	5.818374e-3
GO:0031119	tRNA pseudouridine synthesis	5.818374e-3
GO:0017196	N-terminal peptidyl-methionine acetylation	5.818374e-3
GO:0042228	interleukin-8 biosynthetic process	5.818374e-3
GO:0009215	purine deoxyribonucleoside triphosphate metabolic process	5.874329e-3
GO:0000422	mitochondrion degradation	5.903626e-3
GO:0006006	glucose metabolic process	5.948898e-3
GO:0044237	cellular metabolic process	5.986268e-3
GO:0001302	replicative cell aging	6.006764e-3
GO:0001834	trophectodermal cell proliferation	6.016634e-3
GO:0071539	protein localization to centrosome	6.016634e-3
GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification	6.131397e-3
GO:0000738	DNA catabolic process, exonucleolytic	6.144549e-3
GO:0048168	regulation of neuronal synaptic plasticity	6.161028e-3
GO:0006511	ubiquitin-dependent protein catabolic process	6.186004e-3
GO:0006139	nucleobase-containing compound metabolic process	6.186065e-3
GO:0048102	autophagic cell death	6.225063e-3
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	6.228753e-3
GO:0061034	olfactory bulb mitral cell layer development	6.228753e-3
GO:0045630	positive regulation of T-helper 2 cell differentiation	6.228753e-3
GO:0000070	mitotic sister chromatid segregation	6.327848e-3
GO:0045647	negative regulation of erythrocyte differentiation	6.450480e-3
GO:0045625	regulation of T-helper 1 cell differentiation	6.590565e-3
GO:0006906	vesicle fusion	6.650981e-3
GO:0019941	modification-dependent protein catabolic process	6.698976e-3
GO:0043632	modification-dependent macromolecule catabolic process	6.805027e-3
GO:0015931	nucleobase-containing compound transport	6.812788e-3
GO:0009086	methionine biosynthetic process	6.824882e-3
GO:0050658	RNA transport	7.023859e-3
GO:0045948	positive regulation of translational initiation	7.144215e-3
GO:0010952	positive regulation of peptidase activity	7.157974e-3
GO:0048842	positive regulation of axon extension involved in axon guidance	7.375665e-3
GO:0045875	negative regulation of sister chromatid cohesion	7.375665e-3
GO:0051103	DNA ligation involved in DNA repair	7.418637e-3
GO:0006281	DNA repair	7.440361e-3
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	7.663083e-3
GO:0072017	distal tubule development	7.672888e-3
GO:0015986	ATP synthesis coupled proton transport	7.672888e-3
GO:0021853	cerebral cortex GABAergic interneuron migration	7.818152e-3
GO:0014056	regulation of acetylcholine secretion	7.848395e-3
GO:0033091	positive regulation of immature T cell proliferation	7.848395e-3
GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein	7.848395e-3
GO:0032205	negative regulation of telomere maintenance	7.848395e-3
GO:0045908	negative regulation of vasodilation	7.956307e-3
GO:0033092	positive regulation of immature T cell proliferation in thymus	7.956307e-3
GO:0042168	heme metabolic process	7.986018e-3
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	8.031712e-3
GO:0030913	paranodal junction assembly	8.271355e-3
GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	8.294464e-3
GO:0010165	response to X-ray	8.346172e-3
GO:0001840	neural plate development	8.634412e-3
GO:0009648	photoperiodism	8.669651e-3
GO:0015851	nucleobase transport	8.691562e-3
GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	8.832948e-3
GO:0033572	transferrin transport	8.832948e-3
GO:0009107	lipoate biosynthetic process	8.832948e-3
GO:0006437	tyrosyl-tRNA aminoacylation	8.832948e-3
GO:0061025	membrane fusion	8.932831e-3
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	9.040027e-3
GO:0007141	male meiosis I	9.144486e-3
GO:0051900	regulation of mitochondrial depolarization	9.277967e-3
GO:0007080	mitotic metaphase plate congression	9.373913e-3
GO:0006090	pyruvate metabolic process	9.412489e-3
GO:0071603	endothelial cell-cell adhesion	9.505825e-3
GO:0051028	mRNA transport	9.919841e-3
GO:0048341	paraxial mesoderm formation	9.983630e-3
GO:0071922	regulation of cohesin localization to chromatin	1.004208e-2
GO:0051583	dopamine uptake	1.018603e-2
GO:0021843	substrate-independent telencephalic tangential interneuron migration	1.018766e-2
GO:2000016	negative regulation of determination of dorsal identity	1.025879e-2
GO:0000722	telomere maintenance via recombination	1.025879e-2
GO:0009451	RNA modification	1.034257e-2
GO:0007031	peroxisome organization	1.034506e-2
GO:0046604	positive regulation of mitotic centrosome separation	1.052953e-2
GO:0034276	kynurenic acid biosynthetic process	1.052953e-2
GO:0032298	positive regulation of DNA-dependent DNA replication initiation	1.052953e-2
GO:0002534	cytokine production involved in inflammatory response	1.052953e-2
GO:0071843	cellular component biogenesis at cellular level	1.069397e-2
GO:0046963	3'-phosphoadenosine 5'-phosphosulfate transport	1.080489e-2
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	1.080489e-2
GO:0033603	positive regulation of dopamine secretion	1.080489e-2
GO:0007051	spindle organization	1.084154e-2
GO:0006944	cellular membrane fusion	1.100541e-2
GO:0042136	neurotransmitter biosynthetic process	1.105429e-2
GO:0035564	regulation of kidney size	1.113415e-2
GO:0043487	regulation of RNA stability	1.116260e-2
GO:0021895	cerebral cortex neuron differentiation	1.132198e-2
GO:0071824	protein-DNA complex subunit organization	1.146044e-2
GO:0006119	oxidative phosphorylation	1.153576e-2
GO:0061113	pancreas morphogenesis	1.159309e-2
GO:0090342	regulation of cell aging	1.159816e-2
GO:0046329	negative regulation of JNK cascade	1.159816e-2
GO:0022403	cell cycle phase	1.189387e-2
GO:0006364	rRNA processing	1.197316e-2
GO:0000729	DNA double-strand break processing	1.205905e-2
GO:0021997	neural plate axis specification	1.205905e-2
GO:0000414	regulation of histone H3-K36 methylation	1.205905e-2
GO:0042760	very long-chain fatty acid catabolic process	1.209433e-2
GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing	1.209433e-2
GO:0034379	very-low-density lipoprotein particle assembly	1.209433e-2
GO:0031575	mitotic cell cycle G1/S transition checkpoint	1.209750e-2
GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway	1.221173e-2
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	1.221234e-2
GO:0071777	positive regulation of cell cycle cytokinesis	1.228620e-2
GO:0016567	protein ubiquitination	1.230286e-2
GO:0035385	Roundabout signaling pathway	1.253280e-2
GO:0003062	regulation of heart rate by chemical signal	1.258698e-2
GO:0009950	dorsal/ventral axis specification	1.267674e-2
GO:0072240	metanephric DCT cell differentiation	1.276354e-2
GO:0072136	metanephric mesenchymal cell proliferation involved in metanephros development	1.276354e-2
GO:0072227	metanephric macula densa development	1.276354e-2
GO:2000172	regulation of branching morphogenesis of a nerve	1.287424e-2
GO:0006403	RNA localization	1.297273e-2
GO:0032277	negative regulation of gonadotropin secretion	1.306356e-2
GO:0016070	RNA metabolic process	1.306592e-2
GO:0090096	positive regulation of metanephric cap mesenchymal cell proliferation	1.307215e-2
GO:0060947	cardiac vascular smooth muscle cell differentiation	1.332669e-2
GO:0035695	mitochondrion degradation by induced vacuole formation	1.335357e-2
GO:0009217	purine deoxyribonucleoside triphosphate catabolic process	1.335357e-2
GO:0000492	box C/D snoRNP assembly	1.335357e-2
GO:0033013	tetrapyrrole metabolic process	1.382488e-2
GO:0045624	positive regulation of T-helper cell differentiation	1.394252e-2
GO:0006323	DNA packaging	1.398771e-2
GO:0051297	centrosome organization	1.401637e-2
GO:2000045	regulation of G1/S transition of mitotic cell cycle	1.408043e-2
GO:0021587	cerebellum morphogenesis	1.415728e-2
GO:0008637	apoptotic mitochondrial changes	1.419988e-2
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	1.432169e-2
GO:0006333	chromatin assembly or disassembly	1.435805e-2
GO:0001504	neurotransmitter uptake	1.448280e-2
GO:0030502	negative regulation of bone mineralization	1.477913e-2
GO:0006779	porphyrin-containing compound biosynthetic process	1.495534e-2
GO:0035640	exploration behavior	1.521518e-2
GO:0016071	mRNA metabolic process	1.527261e-2
GO:0070171	negative regulation of tooth mineralization	1.528169e-2
GO:0042697	menopause	1.528169e-2
GO:0018242	protein O-linked glycosylation via serine	1.528169e-2
GO:0018243	protein O-linked glycosylation via threonine	1.528169e-2
GO:0045906	negative regulation of vasoconstriction	1.547641e-2
GO:0006538	glutamate catabolic process	1.547641e-2
GO:0032836	glomerular basement membrane development	1.547641e-2
GO:0042053	regulation of dopamine metabolic process	1.554551e-2
GO:0000726	non-recombinational repair	1.554551e-2
GO:0000096	sulfur amino acid metabolic process	1.557543e-2
GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification	1.607392e-2
GO:0030836	positive regulation of actin filament depolymerization	1.607392e-2
GO:0034641	cellular nitrogen compound metabolic process	1.612272e-2
GO:0071786	endoplasmic reticulum tubular network organization	1.625484e-2
GO:0034553	mitochondrial respiratory chain complex II assembly	1.625484e-2
GO:0006561	proline biosynthetic process	1.634414e-2
GO:0018283	iron incorporation into metallo-sulfur cluster	1.634414e-2
GO:0015855	pyrimidine base transport	1.634414e-2
GO:0002828	regulation of type 2 immune response	1.656397e-2
GO:0060264	regulation of respiratory burst involved in inflammatory response	1.681401e-2
GO:0070669	response to interleukin-2	1.681401e-2
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	1.681401e-2
GO:0021568	rhombomere 2 development	1.681401e-2
GO:0007529	establishment of synaptic specificity at neuromuscular junction	1.681401e-2
GO:0010569	regulation of double-strand break repair via homologous recombination	1.695300e-2
GO:0009067	aspartate family amino acid biosynthetic process	1.699448e-2
GO:0051321	meiotic cell cycle	1.736066e-2
GO:0021575	hindbrain morphogenesis	1.737917e-2
GO:0051603	proteolysis involved in cellular protein catabolic process	1.805513e-2
GO:0006367	transcription initiation from RNA polymerase II promoter	1.838647e-2
GO:0046854	phosphatidylinositol phosphorylation	1.844332e-2
GO:0006261	DNA-dependent DNA replication	1.868958e-2
GO:0045628	regulation of T-helper 2 cell differentiation	1.874014e-2
GO:0021877	forebrain neuron fate commitment	1.874014e-2
GO:0060125	negative regulation of growth hormone secretion	1.878114e-2
GO:0072249	metanephric glomerular visceral epithelial cell development	1.878114e-2
GO:0072274	metanephric glomerular basement membrane development	1.878114e-2
GO:2000009	negative regulation of protein localization at cell surface	1.878114e-2
GO:0048677	axon extension involved in regeneration	1.878114e-2
GO:0051463	negative regulation of cortisol secretion	1.878114e-2
GO:0009443	pyridoxal 5'-phosphate salvage	1.878114e-2
GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	1.878114e-2
GO:0021771	lateral geniculate nucleus development	1.878114e-2
GO:0070168	negative regulation of biomineral tissue development	1.878426e-2
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	1.878426e-2
GO:0034105	positive regulation of tissue remodeling	1.896399e-2
GO:0042069	regulation of catecholamine metabolic process	1.911702e-2
GO:0045023	G0 to G1 transition	1.920146e-2
GO:0070194	synaptonemal complex disassembly	1.920146e-2
GO:0070368	positive regulation of hepatocyte differentiation	1.920146e-2
GO:0048313	Golgi inheritance	1.920146e-2
GO:0043046	DNA methylation involved in gamete generation	1.920165e-2
GO:0031063	regulation of histone deacetylation	1.922345e-2
GO:0044257	cellular protein catabolic process	1.925567e-2
GO:0035308	negative regulation of protein dephosphorylation	1.940937e-2
GO:0007052	mitotic spindle organization	1.951167e-2
GO:0043280	positive regulation of caspase activity	1.983612e-2
GO:0061003	positive regulation of dendritic spine morphogenesis	1.984281e-2
GO:0000959	mitochondrial RNA metabolic process	2.026169e-2
GO:0035967	cellular response to topologically incorrect protein	2.029965e-2
GO:0006105	succinate metabolic process	2.033702e-2
GO:0046060	dATP metabolic process	2.066297e-2
GO:0072236	metanephric loop of Henle development	2.086509e-2
GO:0043153	entrainment of circadian clock by photoperiod	2.096044e-2
GO:0060829	negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation	2.116718e-2
GO:0070922	small RNA loading onto RISC	2.116718e-2
GO:0060381	positive regulation of single-stranded telomeric DNA binding	2.116718e-2
GO:0035750	protein localization to myelin sheath abaxonal region	2.116718e-2
GO:0034721	histone H3-K4 demethylation, trimethyl-H3-K4-specific	2.116718e-2
GO:0009057	macromolecule catabolic process	2.127187e-2
GO:0050925	negative regulation of negative chemotaxis	2.131194e-2
GO:0010936	negative regulation of macrophage cytokine production	2.131194e-2
GO:0021903	rostrocaudal neural tube patterning	2.144116e-2
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	2.155127e-2
GO:0090403	oxidative stress-induced premature senescence	2.158088e-2
GO:0046322	negative regulation of fatty acid oxidation	2.158088e-2
GO:0060060	post-embryonic retina morphogenesis in camera-type eye	2.164383e-2
GO:0070166	enamel mineralization	2.164383e-2
GO:0032808	lacrimal gland development	2.187233e-2
GO:0007098	centrosome cycle	2.208744e-2
GO:0032222	regulation of synaptic transmission, cholinergic	2.241067e-2
GO:0060405	regulation of penile erection	2.261338e-2
GO:0060046	regulation of acrosome reaction	2.261338e-2
GO:0009798	axis specification	2.271754e-2
GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	2.291568e-2
GO:0072361	regulation of glycolysis by regulation of transcription from RNA polymerase II promoter	2.291568e-2
GO:0006390	transcription from mitochondrial promoter	2.291568e-2
GO:0000413	protein peptidyl-prolyl isomerization	2.301247e-2
GO:0021696	cerebellar cortex morphogenesis	2.331342e-2
GO:0009200	deoxyribonucleoside triphosphate metabolic process	2.368784e-2
GO:0008631	induction of apoptosis by oxidative stress	2.370967e-2
GO:0006107	oxaloacetate metabolic process	2.409298e-2
GO:0060012	synaptic transmission, glycinergic	2.428851e-2
GO:0030423	targeting of mRNA for destruction involved in RNA interference	2.428851e-2
GO:0042789	mRNA transcription from RNA polymerase II promoter	2.428851e-2
GO:0006268	DNA unwinding involved in replication	2.439225e-2
GO:0016072	rRNA metabolic process	2.450610e-2
GO:0043508	negative regulation of JUN kinase activity	2.492515e-2
GO:0090311	regulation of protein deacetylation	2.495458e-2
GO:0071205	protein localization to juxtaparanode region of axon	2.549773e-2
GO:0044091	membrane biogenesis	2.549773e-2
GO:0014034	neural crest cell fate commitment	2.549773e-2
GO:0033148	positive regulation of estrogen receptor signaling pathway	2.574245e-2
GO:0016540	protein autoprocessing	2.574245e-2
GO:0043170	macromolecule metabolic process	2.600478e-2
GO:0061136	regulation of proteasomal protein catabolic process	2.628461e-2
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	2.629445e-2
GO:0046128	purine ribonucleoside metabolic process	2.637675e-2
GO:0046364	monosaccharide biosynthetic process	2.650423e-2
GO:0021796	cerebral cortex regionalization	2.663302e-2
GO:0008542	visual learning	2.681053e-2
GO:0006783	heme biosynthetic process	2.685378e-2
GO:0031508	centromeric heterochromatin formation	2.691645e-2
GO:0045345	positive regulation of MHC class I biosynthetic process	2.691645e-2
GO:0006669	sphinganine-1-phosphate biosynthetic process	2.691645e-2
GO:0043923	positive regulation by host of viral transcription	2.705772e-2
GO:0090344	negative regulation of cell aging	2.750655e-2
GO:0006678	glucosylceramide metabolic process	2.750655e-2
GO:0070593	dendrite self-avoidance	2.754132e-2
GO:0032530	regulation of microvillus organization	2.754132e-2