Novel motif:57

name:	motif57_AGGCAT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0050896	response to stimulus	1.708526e-24
GO:0032501	multicellular organismal process	5.018302e-23
GO:0051179	localization	7.533502e-23
GO:0007154	cell communication	1.404220e-21
GO:0051716	cellular response to stimulus	1.707766e-21
GO:0051234	establishment of localization	4.837354e-20
GO:0006810	transport	8.596069e-20
GO:0023052	signaling	1.448875e-18
GO:0065008	regulation of biological quality	5.150781e-18
GO:0006811	ion transport	1.004446e-16
GO:0071840	cellular component organization or biogenesis	2.927484e-16
GO:0006950	response to stress	3.539735e-16
GO:0016043	cellular component organization	1.013006e-15
GO:0007165	signal transduction	7.857081e-15
GO:0006629	lipid metabolic process	1.038699e-14
GO:0032502	developmental process	2.184585e-14
GO:0032879	regulation of localization	2.416178e-14
GO:0044085	cellular component biogenesis	2.501753e-14
GO:0006812	cation transport	3.535441e-14
GO:0019836	hemolysis by symbiont of host erythrocytes	4.696297e-14
GO:0048856	anatomical structure development	7.725356e-14
GO:0022607	cellular component assembly	1.816604e-13
GO:0044281	small molecule metabolic process	2.953302e-13
GO:0043933	macromolecular complex subunit organization	3.883030e-13
GO:0009987	cellular process	6.877534e-13
GO:0051883	killing of cells in other organism involved in symbiotic interaction	9.950272e-13
GO:0007525	somatic muscle development	1.109125e-12
GO:0002376	immune system process	1.122349e-12
GO:0003008	system process	1.292479e-12
GO:0010033	response to organic substance	1.710492e-12
GO:0065007	biological regulation	2.035629e-12
GO:0006082	organic acid metabolic process	2.746024e-12
GO:0007155	cell adhesion	4.169707e-12
GO:0042180	cellular ketone metabolic process	4.493206e-12
GO:0051259	protein oligomerization	6.162969e-12
GO:0019752	carboxylic acid metabolic process	9.623114e-12
GO:0065003	macromolecular complex assembly	1.226770e-11
GO:0051336	regulation of hydrolase activity	1.492740e-11
GO:0048518	positive regulation of biological process	2.249816e-11
GO:0010941	regulation of cell death	3.502814e-11
GO:0007275	multicellular organismal development	4.790849e-11
GO:0051704	multi-organism process	5.058518e-11
GO:0048519	negative regulation of biological process	6.017946e-11
GO:0007166	cell surface receptor linked signaling pathway	7.805280e-11
GO:0010876	lipid localization	1.083969e-10
GO:0030001	metal ion transport	1.345712e-10
GO:0048514	blood vessel morphogenesis	1.363854e-10
GO:0048731	system development	2.177276e-10
GO:0050789	regulation of biological process	3.137483e-10
GO:0048075	positive regulation of eye pigmentation	4.503494e-10
GO:0051049	regulation of transport	4.723470e-10
GO:0048608	reproductive structure development	5.197052e-10
GO:0044255	cellular lipid metabolic process	6.124157e-10
GO:0043067	regulation of programmed cell death	6.292235e-10
GO:0071622	regulation of granulocyte chemotaxis	6.444962e-10
GO:0009617	response to bacterium	8.595580e-10
GO:0070482	response to oxygen levels	9.929314e-10
GO:0010038	response to metal ion	1.080801e-9
GO:0046661	male sex differentiation	1.182211e-9
GO:0010035	response to inorganic substance	1.354500e-9
GO:0046546	development of primary male sexual characteristics	1.457355e-9
GO:0010758	regulation of macrophage chemotaxis	1.582309e-9
GO:0032320	positive regulation of Ras GTPase activity	1.637779e-9
GO:0035556	intracellular signal transduction	1.640158e-9
GO:0070555	response to interleukin-1	1.651522e-9
GO:0044106	cellular amine metabolic process	1.737907e-9
GO:0010759	positive regulation of macrophage chemotaxis	1.902477e-9
GO:0006952	defense response	2.063451e-9
GO:0048522	positive regulation of cellular process	2.806715e-9
GO:0042981	regulation of apoptosis	2.952265e-9
GO:0010565	regulation of cellular ketone metabolic process	3.973403e-9
GO:0007584	response to nutrient	4.820569e-9
GO:0048523	negative regulation of cellular process	4.887537e-9
GO:0032318	regulation of Ras GTPase activity	5.121292e-9
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	5.186511e-9
GO:0042221	response to chemical stimulus	6.473617e-9
GO:0071675	regulation of mononuclear cell migration	6.572982e-9
GO:0048073	regulation of eye pigmentation	6.673065e-9
GO:0045616	regulation of keratinocyte differentiation	6.955937e-9
GO:0008584	male gonad development	7.767177e-9
GO:0012501	programmed cell death	7.960479e-9
GO:0022414	reproductive process	8.649023e-9
GO:0048513	organ development	1.108989e-8
GO:0000003	reproduction	1.110339e-8
GO:0042157	lipoprotein metabolic process	1.144765e-8
GO:0009566	fertilization	1.225640e-8
GO:0032571	response to vitamin K	1.281598e-8
GO:0048878	chemical homeostasis	1.604529e-8
GO:0045604	regulation of epidermal cell differentiation	1.624903e-8
GO:0030301	cholesterol transport	1.636466e-8
GO:0016265	death	1.645662e-8
GO:0043087	regulation of GTPase activity	1.717850e-8
GO:0050801	ion homeostasis	1.722517e-8
GO:0042127	regulation of cell proliferation	1.734363e-8
GO:0009611	response to wounding	1.797518e-8
GO:0009628	response to abiotic stimulus	1.938071e-8
GO:0008219	cell death	2.031426e-8
GO:0001666	response to hypoxia	2.139787e-8
GO:0051239	regulation of multicellular organismal process	2.253370e-8
GO:0071822	protein complex subunit organization	2.334996e-8
GO:0006955	immune response	3.052522e-8
GO:0006869	lipid transport	3.087307e-8
GO:0043269	regulation of ion transport	3.201718e-8
GO:0033124	regulation of GTP catabolic process	3.354927e-8
GO:0008202	steroid metabolic process	3.538671e-8
GO:0051262	protein tetramerization	3.548664e-8
GO:0072507	divalent inorganic cation homeostasis	3.695996e-8
GO:0060047	heart contraction	3.995189e-8
GO:0006915	apoptosis	4.084009e-8
GO:0009653	anatomical structure morphogenesis	4.259972e-8
GO:0032940	secretion by cell	4.355339e-8
GO:0030101	natural killer cell activation	4.395041e-8
GO:0015918	sterol transport	4.813795e-8
GO:0007296	vitellogenesis	4.899051e-8
GO:0031667	response to nutrient levels	5.110197e-8
GO:0009888	tissue development	5.508045e-8
GO:0015721	bile acid and bile salt transport	5.707239e-8
GO:0032269	negative regulation of cellular protein metabolic process	5.840686e-8
GO:0051345	positive regulation of hydrolase activity	5.990104e-8
GO:0045137	development of primary sexual characteristics	6.065129e-8
GO:0070278	extracellular matrix constituent secretion	6.608052e-8
GO:0010260	organ senescence	6.608052e-8
GO:0019216	regulation of lipid metabolic process	7.343910e-8
GO:0009308	amine metabolic process	7.489885e-8
GO:0050790	regulation of catalytic activity	7.629024e-8
GO:0044093	positive regulation of molecular function	7.870053e-8
GO:0016559	peroxisome fission	8.193569e-8
GO:0071702	organic substance transport	8.499930e-8
GO:0042158	lipoprotein biosynthetic process	8.539297e-8
GO:0009894	regulation of catabolic process	9.418995e-8
GO:0031329	regulation of cellular catabolic process	9.532019e-8
GO:0048583	regulation of response to stimulus	9.553149e-8
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	9.905997e-8
GO:0014823	response to activity	1.032500e-7
GO:0010269	response to selenium ion	1.068947e-7
GO:0051246	regulation of protein metabolic process	1.116598e-7
GO:0008406	gonad development	1.160327e-7
GO:0055074	calcium ion homeostasis	1.172573e-7
GO:0051385	response to mineralocorticoid stimulus	1.216698e-7
GO:0006928	cellular component movement	1.253253e-7
GO:0032868	response to insulin stimulus	1.282468e-7
GO:0051260	protein homooligomerization	1.305577e-7
GO:0072503	cellular divalent inorganic cation homeostasis	1.366079e-7
GO:0008015	blood circulation	1.378248e-7
GO:0007028	cytoplasm organization	1.410650e-7
GO:0032026	response to magnesium ion	1.429198e-7
GO:0050877	neurological system process	1.432611e-7
GO:0007267	cell-cell signaling	1.449940e-7
GO:0006874	cellular calcium ion homeostasis	1.515154e-7
GO:0070887	cellular response to chemical stimulus	1.643639e-7
GO:0070541	response to platinum ion	1.665460e-7
GO:0006873	cellular ion homeostasis	1.700829e-7
GO:0034097	response to cytokine stimulus	1.749670e-7
GO:0043085	positive regulation of catalytic activity	1.811876e-7
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	1.883015e-7
GO:0006520	cellular amino acid metabolic process	1.941241e-7
GO:0051056	regulation of small GTPase mediated signal transduction	2.070476e-7
GO:0006461	protein complex assembly	2.180474e-7
GO:0055065	metal ion homeostasis	2.468132e-7
GO:0001944	vasculature development	2.569102e-7
GO:0030334	regulation of cell migration	2.668978e-7
GO:0031640	killing of cells of other organism	2.971366e-7
GO:0006140	regulation of nucleotide metabolic process	3.107122e-7
GO:0010648	negative regulation of cell communication	3.111392e-7
GO:0048585	negative regulation of response to stimulus	3.117611e-7
GO:0051248	negative regulation of protein metabolic process	3.118350e-7
GO:0023057	negative regulation of signaling	3.170741e-7
GO:0003012	muscle system process	3.261394e-7
GO:0006875	cellular metal ion homeostasis	3.267181e-7
GO:0055080	cation homeostasis	3.276118e-7
GO:0001568	blood vessel development	3.431499e-7
GO:0009607	response to biotic stimulus	3.913544e-7
GO:0050878	regulation of body fluid levels	3.965763e-7
GO:0070271	protein complex biogenesis	3.976290e-7
GO:0008217	regulation of blood pressure	4.010693e-7
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	4.031440e-7
GO:0046903	secretion	4.103769e-7
GO:0060571	morphogenesis of an epithelial fold	4.151344e-7
GO:0060048	cardiac muscle contraction	4.216440e-7
GO:0010942	positive regulation of cell death	4.306892e-7
GO:0048870	cell motility	4.519669e-7
GO:0032787	monocarboxylic acid metabolic process	5.228355e-7
GO:0043069	negative regulation of programmed cell death	5.268029e-7
GO:0033121	regulation of purine nucleotide catabolic process	5.586795e-7
GO:0043316	cytotoxic T cell degranulation	5.715558e-7
GO:0015672	monovalent inorganic cation transport	5.721197e-7
GO:0051659	maintenance of mitochondrion location	5.990799e-7
GO:0033273	response to vitamin	6.186964e-7
GO:0009968	negative regulation of signal transduction	6.202624e-7
GO:0006936	muscle contraction	6.240694e-7
GO:0007186	G-protein coupled receptor protein signaling pathway	6.815342e-7
GO:0003374	dynamin polymerization involved in mitochondrial fission	6.836143e-7
GO:0090149	membrane fission involved in mitochondrial fission	6.836143e-7
GO:0070318	positive regulation of G0 to G1 transition	6.889956e-7
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	7.950997e-7
GO:0006916	anti-apoptosis	8.114081e-7
GO:0042310	vasoconstriction	8.662308e-7
GO:0042537	benzene-containing compound metabolic process	8.740717e-7
GO:0051649	establishment of localization in cell	8.876942e-7
GO:2000145	regulation of cell motility	8.955785e-7
GO:0030193	regulation of blood coagulation	9.539951e-7
GO:0032268	regulation of cellular protein metabolic process	9.974976e-7
GO:0040012	regulation of locomotion	1.007756e-6
GO:0048660	regulation of smooth muscle cell proliferation	1.071204e-6
GO:0051707	response to other organism	1.157255e-6
GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	1.169312e-6
GO:0055082	cellular chemical homeostasis	1.189121e-6
GO:0051271	negative regulation of cellular component movement	1.193175e-6
GO:0031960	response to corticosteroid stimulus	1.203125e-6
GO:0034381	plasma lipoprotein particle clearance	1.210037e-6
GO:0061024	membrane organization	1.241218e-6
GO:0048661	positive regulation of smooth muscle cell proliferation	1.254186e-6
GO:0009725	response to hormone stimulus	1.268099e-6
GO:0050820	positive regulation of coagulation	1.268884e-6
GO:0019217	regulation of fatty acid metabolic process	1.272403e-6
GO:0032101	regulation of response to external stimulus	1.274984e-6
GO:0030003	cellular cation homeostasis	1.412495e-6
GO:0044283	small molecule biosynthetic process	1.423440e-6
GO:0009719	response to endogenous stimulus	1.436443e-6
GO:0050818	regulation of coagulation	1.470279e-6
GO:0018958	phenol-containing compound metabolic process	1.470458e-6
GO:0060548	negative regulation of cell death	1.537207e-6
GO:0070316	regulation of G0 to G1 transition	1.572943e-6
GO:0009129	pyrimidine nucleoside monophosphate metabolic process	1.588945e-6
GO:0051270	regulation of cellular component movement	1.628118e-6
GO:0045682	regulation of epidermis development	1.631546e-6
GO:0043066	negative regulation of apoptosis	1.638234e-6
GO:0035150	regulation of tube size	1.711706e-6
GO:0007268	synaptic transmission	1.727113e-6
GO:0050880	regulation of blood vessel size	1.752317e-6
GO:0050794	regulation of cellular process	1.766709e-6
GO:0016192	vesicle-mediated transport	2.062855e-6
GO:0061084	negative regulation of protein refolding	2.133425e-6
GO:2000026	regulation of multicellular organismal development	2.225393e-6
GO:0016044	cellular membrane organization	2.365653e-6
GO:0003018	vascular process in circulatory system	2.417783e-6
GO:0052547	regulation of peptidase activity	2.440503e-6
GO:0033993	response to lipid	2.574632e-6
GO:0019226	transmission of nerve impulse	2.593886e-6
GO:0009991	response to extracellular stimulus	2.676870e-6
GO:0006222	UMP biosynthetic process	2.802719e-6
GO:0042060	wound healing	2.821571e-6
GO:0043547	positive regulation of GTPase activity	2.825118e-6
GO:0016998	cell wall macromolecule catabolic process	2.837120e-6
GO:0003013	circulatory system process	2.915740e-6
GO:0006575	cellular modified amino acid metabolic process	3.008213e-6
GO:0030154	cell differentiation	3.123106e-6
GO:0007548	sex differentiation	3.147369e-6
GO:0001525	angiogenesis	3.159987e-6
GO:0051384	response to glucocorticoid stimulus	3.389438e-6
GO:0010594	regulation of endothelial cell migration	3.575891e-6
GO:0006911	phagocytosis, engulfment	3.595206e-6
GO:0007596	blood coagulation	3.598182e-6
GO:0010955	negative regulation of protein processing	3.662258e-6
GO:0006642	triglyceride mobilization	3.714184e-6
GO:0003006	developmental process involved in reproduction	3.745168e-6
GO:0032914	positive regulation of transforming growth factor beta1 production	3.780635e-6
GO:0065009	regulation of molecular function	3.810291e-6
GO:0050793	regulation of developmental process	3.866079e-6
GO:0019538	protein metabolic process	4.196399e-6
GO:0071379	cellular response to prostaglandin stimulus	4.231041e-6
GO:0034374	low-density lipoprotein particle remodeling	4.504714e-6
GO:0032103	positive regulation of response to external stimulus	4.670746e-6
GO:0000245	spliceosome assembly	4.753628e-6
GO:0021509	roof plate formation	4.755024e-6
GO:0043101	purine-containing compound salvage	4.926919e-6
GO:0010817	regulation of hormone levels	5.211092e-6
GO:0072358	cardiovascular system development	5.462119e-6
GO:0046464	acylglycerol catabolic process	5.545199e-6
GO:0048646	anatomical structure formation involved in morphogenesis	5.552348e-6
GO:0007599	hemostasis	5.612291e-6
GO:0019827	stem cell maintenance	5.737856e-6
GO:0007565	female pregnancy	5.914082e-6
GO:0023051	regulation of signaling	5.964658e-6
GO:0016525	negative regulation of angiogenesis	6.037690e-6
GO:0051235	maintenance of location	6.444187e-6
GO:0071842	cellular component organization at cellular level	6.638709e-6
GO:0010595	positive regulation of endothelial cell migration	6.747300e-6
GO:0033194	response to hydroperoxide	6.755951e-6
GO:0071841	cellular component organization or biogenesis at cellular level	6.902688e-6
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	7.014411e-6
GO:0019433	triglyceride catabolic process	7.076845e-6
GO:0048468	cell development	7.199029e-6
GO:0048869	cellular developmental process	7.221041e-6
GO:2000146	negative regulation of cell motility	7.221935e-6
GO:0033554	cellular response to stress	7.270332e-6
GO:0051093	negative regulation of developmental process	7.395377e-6
GO:0009966	regulation of signal transduction	7.539535e-6
GO:0014889	muscle atrophy	7.766365e-6
GO:0090066	regulation of anatomical structure size	7.781618e-6
GO:0016477	cell migration	8.078757e-6
GO:0006214	thymidine catabolic process	8.191446e-6
GO:0002237	response to molecule of bacterial origin	8.681366e-6
GO:0042119	neutrophil activation	9.023272e-6
GO:0045765	regulation of angiogenesis	9.393200e-6
GO:0046503	glycerolipid catabolic process	9.760078e-6
GO:0046104	thymidine metabolic process	9.860173e-6
GO:0048609	multicellular organismal reproductive process	9.864351e-6
GO:0032924	activin receptor signaling pathway	9.964595e-6
GO:0002090	regulation of receptor internalization	9.991513e-6
GO:0006518	peptide metabolic process	1.002099e-5
GO:0010631	epithelial cell migration	1.013715e-5
GO:0072593	reactive oxygen species metabolic process	1.018077e-5
GO:0044267	cellular protein metabolic process	1.029934e-5
GO:0002690	positive regulation of leukocyte chemotaxis	1.030944e-5
GO:0032496	response to lipopolysaccharide	1.038907e-5
GO:0044036	cell wall macromolecule metabolic process	1.065362e-5
GO:0008207	C21-steroid hormone metabolic process	1.081558e-5
GO:0006982	response to lipid hydroperoxide	1.134896e-5
GO:0002238	response to molecule of fungal origin	1.193287e-5
GO:0002544	chronic inflammatory response	1.203515e-5
GO:0042325	regulation of phosphorylation	1.256049e-5
GO:0043068	positive regulation of programmed cell death	1.301136e-5
GO:0030856	regulation of epithelial cell differentiation	1.344079e-5
GO:0009893	positive regulation of metabolic process	1.370627e-5
GO:0044419	interspecies interaction between organisms	1.375580e-5
GO:0048489	synaptic vesicle transport	1.451715e-5
GO:0019220	regulation of phosphate metabolic process	1.518327e-5
GO:0021527	spinal cord association neuron differentiation	1.521237e-5
GO:0050900	leukocyte migration	1.525131e-5
GO:0034369	plasma lipoprotein particle remodeling	1.534519e-5
GO:0034765	regulation of ion transmembrane transport	1.537205e-5
GO:0014829	vascular smooth muscle contraction	1.537944e-5
GO:0019725	cellular homeostasis	1.599017e-5
GO:0032869	cellular response to insulin stimulus	1.607566e-5
GO:0048641	regulation of skeletal muscle tissue development	1.624588e-5
GO:0019229	regulation of vasoconstriction	1.662780e-5
GO:0071844	cellular component assembly at cellular level	1.670844e-5
GO:0010646	regulation of cell communication	1.681448e-5
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	1.693471e-5
GO:0031399	regulation of protein modification process	1.748434e-5
GO:0030168	platelet activation	1.819743e-5
GO:0006631	fatty acid metabolic process	1.904995e-5
GO:0006725	cellular aromatic compound metabolic process	1.965825e-5
GO:0002687	positive regulation of leukocyte migration	2.000032e-5
GO:0070542	response to fatty acid	2.005862e-5
GO:0071345	cellular response to cytokine stimulus	2.060986e-5
GO:0007021	tubulin complex assembly	2.085117e-5
GO:0010744	positive regulation of macrophage derived foam cell differentiation	2.125532e-5
GO:0048520	positive regulation of behavior	2.206390e-5
GO:0006066	alcohol metabolic process	2.238103e-5
GO:0051412	response to corticosterone stimulus	2.285771e-5
GO:0007167	enzyme linked receptor protein signaling pathway	2.295178e-5
GO:0034383	low-density lipoprotein particle clearance	2.324974e-5
GO:0007276	gamete generation	2.399154e-5
GO:0043434	response to peptide hormone stimulus	2.436533e-5
GO:0019953	sexual reproduction	2.441500e-5
GO:0006633	fatty acid biosynthetic process	2.453012e-5
GO:0001932	regulation of protein phosphorylation	2.483070e-5
GO:0051050	positive regulation of transport	2.524053e-5
GO:0009266	response to temperature stimulus	2.526315e-5
GO:0001775	cell activation	2.593327e-5
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	2.594585e-5
GO:0071843	cellular component biogenesis at cellular level	2.597001e-5
GO:0030336	negative regulation of cell migration	2.606697e-5
GO:0046689	response to mercury ion	2.625557e-5
GO:0001906	cell killing	2.646643e-5
GO:0001692	histamine metabolic process	2.687175e-5
GO:0043652	engulfment of apoptotic cell	2.699447e-5
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	2.699447e-5
GO:0010754	negative regulation of cGMP-mediated signaling	2.699447e-5
GO:0010751	negative regulation of nitric oxide mediated signal transduction	2.699447e-5
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	2.699447e-5
GO:0090287	regulation of cellular response to growth factor stimulus	2.764350e-5
GO:0043065	positive regulation of apoptosis	2.815652e-5
GO:0051046	regulation of secretion	2.817600e-5
GO:0061008	hepaticobiliary system development	2.838894e-5
GO:0070101	positive regulation of chemokine-mediated signaling pathway	2.850405e-5
GO:0071347	cellular response to interleukin-1	2.956682e-5
GO:0042592	homeostatic process	2.964845e-5
GO:0031057	negative regulation of histone modification	3.095416e-5
GO:0032402	melanosome transport	3.181598e-5
GO:0033327	Leydig cell differentiation	3.236529e-5
GO:0018200	peptidyl-glutamic acid modification	3.250193e-5
GO:0002040	sprouting angiogenesis	3.289213e-5
GO:0048864	stem cell development	3.318590e-5
GO:0045575	basophil activation	3.329209e-5
GO:0001694	histamine biosynthetic process	3.329209e-5
GO:0022406	membrane docking	3.399404e-5
GO:0061041	regulation of wound healing	3.417037e-5
GO:0071599	otic vesicle development	3.493802e-5
GO:0034379	very-low-density lipoprotein particle assembly	3.503780e-5
GO:0007264	small GTPase mediated signal transduction	3.559309e-5
GO:0042108	positive regulation of cytokine biosynthetic process	3.563598e-5
GO:0030194	positive regulation of blood coagulation	3.630575e-5
GO:0048610	cellular process involved in reproduction	3.634742e-5
GO:0051240	positive regulation of multicellular organismal process	3.653609e-5
GO:0008285	negative regulation of cell proliferation	3.718119e-5
GO:0010466	negative regulation of peptidase activity	3.731621e-5
GO:0006212	uracil catabolic process	3.763645e-5
GO:0006210	thymine catabolic process	3.763645e-5
GO:0006813	potassium ion transport	3.783731e-5
GO:0003015	heart process	3.790652e-5
GO:0042632	cholesterol homeostasis	3.828753e-5
GO:0006897	endocytosis	3.982022e-5
GO:0048592	eye morphogenesis	4.262492e-5
GO:0001542	ovulation from ovarian follicle	4.279837e-5
GO:0030155	regulation of cell adhesion	4.289583e-5
GO:0043409	negative regulation of MAPKKK cascade	4.342111e-5
GO:0032319	regulation of Rho GTPase activity	4.615052e-5
GO:0042445	hormone metabolic process	4.631584e-5
GO:0006687	glycosphingolipid metabolic process	4.860315e-5
GO:0045764	positive regulation of cellular amino acid metabolic process	4.903910e-5
GO:0006887	exocytosis	4.945260e-5
GO:0045087	innate immune response	5.058659e-5
GO:0006091	generation of precursor metabolites and energy	5.098701e-5
GO:0019695	choline metabolic process	5.213361e-5
GO:0043653	mitochondrial fragmentation involved in apoptosis	5.315516e-5
GO:0045923	positive regulation of fatty acid metabolic process	5.481973e-5
GO:0034605	cellular response to heat	5.681234e-5
GO:0006144	purine base metabolic process	5.748673e-5
GO:0006638	neutral lipid metabolic process	5.786261e-5
GO:0040013	negative regulation of locomotion	5.820342e-5
GO:0046578	regulation of Ras protein signal transduction	5.907075e-5
GO:0050921	positive regulation of chemotaxis	5.925195e-5
GO:0032321	positive regulation of Rho GTPase activity	5.984217e-5
GO:0002688	regulation of leukocyte chemotaxis	6.153754e-5
GO:0006110	regulation of glycolysis	6.335869e-5
GO:0009120	deoxyribonucleoside metabolic process	6.403885e-5
GO:0034377	plasma lipoprotein particle assembly	6.405139e-5
GO:0032908	regulation of transforming growth factor beta1 production	6.565264e-5
GO:0046545	development of primary female sexual characteristics	6.744750e-5
GO:0009408	response to heat	6.806964e-5
GO:0051291	protein heterooligomerization	6.808773e-5
GO:0055085	transmembrane transport	7.011107e-5
GO:0051641	cellular localization	7.313487e-5
GO:0042035	regulation of cytokine biosynthetic process	7.352557e-5
GO:0022613	ribonucleoprotein complex biogenesis	7.434760e-5
GO:0006641	triglyceride metabolic process	7.442598e-5
GO:0034059	response to anoxia	7.582917e-5
GO:0001889	liver development	7.693318e-5
GO:0015718	monocarboxylic acid transport	7.807316e-5
GO:0006435	threonyl-tRNA aminoacylation	7.826277e-5
GO:0032400	melanosome localization	7.848807e-5
GO:0010632	regulation of epithelial cell migration	7.943858e-5
GO:0033552	response to vitamin B3	8.052951e-5
GO:0034220	ion transmembrane transport	8.059991e-5
GO:2000611	positive regulation of thyroid hormone generation	8.177776e-5
GO:0042554	superoxide anion generation	8.299297e-5
GO:0034284	response to monosaccharide stimulus	8.353436e-5
GO:0006497	protein lipidation	8.410768e-5
GO:0040011	locomotion	8.656967e-5
GO:0042159	lipoprotein catabolic process	8.733166e-5
GO:0031400	negative regulation of protein modification process	8.869344e-5
GO:0032401	establishment of melanosome localization	8.903013e-5
GO:0015705	iodide transport	8.903835e-5
GO:0006997	nucleus organization	9.138274e-5
GO:0046394	carboxylic acid biosynthetic process	9.352284e-5
GO:0071356	cellular response to tumor necrosis factor	9.383437e-5
GO:0070098	chemokine-mediated signaling pathway	9.549990e-5
GO:0034382	chylomicron remnant clearance	9.624418e-5
GO:0048741	skeletal muscle fiber development	9.682326e-5
GO:0030317	sperm motility	1.048566e-4
GO:0016202	regulation of striated muscle tissue development	1.053510e-4
GO:0008152	metabolic process	1.058604e-4
GO:0031099	regeneration	1.080766e-4
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	1.102339e-4
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	1.109849e-4
GO:0006968	cellular defense response	1.118874e-4
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	1.119486e-4
GO:0008610	lipid biosynthetic process	1.122896e-4
GO:0042953	lipoprotein transport	1.124137e-4
GO:0010757	negative regulation of plasminogen activation	1.127860e-4
GO:0048145	regulation of fibroblast proliferation	1.137885e-4
GO:0045358	negative regulation of interferon-beta biosynthetic process	1.142002e-4
GO:0051346	negative regulation of hydrolase activity	1.144080e-4
GO:0042327	positive regulation of phosphorylation	1.168963e-4
GO:0006814	sodium ion transport	1.174143e-4
GO:0030031	cell projection assembly	1.188877e-4
GO:0045666	positive regulation of neuron differentiation	1.189503e-4
GO:0048246	macrophage chemotaxis	1.189942e-4
GO:0048087	positive regulation of developmental pigmentation	1.189942e-4
GO:0051904	pigment granule transport	1.205351e-4
GO:0048853	forebrain morphogenesis	1.237358e-4
GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity	1.241897e-4
GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway	1.241897e-4
GO:0034694	response to prostaglandin stimulus	1.244407e-4
GO:0097006	regulation of plasma lipoprotein particle levels	1.252468e-4
GO:0031325	positive regulation of cellular metabolic process	1.254194e-4
GO:0010886	positive regulation of cholesterol storage	1.261045e-4
GO:0006418	tRNA aminoacylation for protein translation	1.262394e-4
GO:0051651	maintenance of location in cell	1.271127e-4
GO:0010517	regulation of phospholipase activity	1.286080e-4
GO:0051657	maintenance of organelle location	1.301535e-4
GO:0006711	estrogen catabolic process	1.306937e-4
GO:0033240	positive regulation of cellular amine metabolic process	1.316378e-4
GO:0006939	smooth muscle contraction	1.348884e-4
GO:0051482	elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger	1.355796e-4
GO:2000210	positive regulation of anoikis	1.368303e-4
GO:0071827	plasma lipoprotein particle organization	1.390756e-4
GO:0001921	positive regulation of receptor recycling	1.399563e-4
GO:0044238	primary metabolic process	1.433656e-4
GO:0046320	regulation of fatty acid oxidation	1.449177e-4
GO:0051480	cytosolic calcium ion homeostasis	1.468885e-4
GO:0051289	protein homotetramerization	1.477029e-4
GO:0007204	elevation of cytosolic calcium ion concentration	1.517962e-4
GO:0006412	translation	1.528781e-4
GO:0043252	sodium-independent organic anion transport	1.550186e-4
GO:0071456	cellular response to hypoxia	1.553198e-4
GO:0048147	negative regulation of fibroblast proliferation	1.589641e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0050896	response to stimulus	6.333260e-15
GO:0006952	defense response	2.649732e-14
GO:0044255	cellular lipid metabolic process	7.876438e-12
GO:0006950	response to stress	1.746616e-11
GO:0006629	lipid metabolic process	1.880055e-11
GO:0032787	monocarboxylic acid metabolic process	8.815720e-11
GO:0032501	multicellular organismal process	9.307678e-11
GO:0006941	striated muscle contraction	1.126606e-10
GO:0051707	response to other organism	9.344821e-10
GO:0008610	lipid biosynthetic process	1.283253e-9
GO:0001887	selenium compound metabolic process	2.554091e-9
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	3.298328e-9
GO:0006082	organic acid metabolic process	4.557633e-9
GO:0009607	response to biotic stimulus	6.297443e-9
GO:0065008	regulation of biological quality	7.205502e-9
GO:0009617	response to bacterium	1.201312e-8
GO:0002684	positive regulation of immune system process	1.301181e-8
GO:0050865	regulation of cell activation	2.482438e-8
GO:0006936	muscle contraction	2.837369e-8
GO:0042180	cellular ketone metabolic process	3.203842e-8
GO:0019752	carboxylic acid metabolic process	3.434941e-8
GO:0002455	humoral immune response mediated by circulating immunoglobulin	3.602301e-8
GO:0002682	regulation of immune system process	4.206501e-8
GO:0051179	localization	5.036474e-8
GO:0002694	regulation of leukocyte activation	5.166456e-8
GO:0009611	response to wounding	5.806518e-8
GO:0006958	complement activation, classical pathway	8.198317e-8
GO:0002253	activation of immune response	8.946985e-8
GO:0006956	complement activation	9.725562e-8
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	1.280367e-7
GO:0006631	fatty acid metabolic process	1.294272e-7
GO:0006633	fatty acid biosynthetic process	1.304485e-7
GO:0050953	sensory perception of light stimulus	1.589750e-7
GO:0044130	negative regulation of growth of symbiont in host	1.630832e-7
GO:0007601	visual perception	1.651398e-7
GO:0048304	positive regulation of isotype switching to IgG isotypes	1.785735e-7
GO:0019835	cytolysis	2.180790e-7
GO:0042221	response to chemical stimulus	2.334493e-7
GO:0050776	regulation of immune response	2.443822e-7
GO:0032101	regulation of response to external stimulus	2.754138e-7
GO:0072376	protein activation cascade	2.777720e-7
GO:0042742	defense response to bacterium	2.965519e-7
GO:0048302	regulation of isotype switching to IgG isotypes	3.139834e-7
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	3.216960e-7
GO:0043462	regulation of ATPase activity	4.640760e-7
GO:0007166	cell surface receptor linked signaling pathway	5.171171e-7
GO:0003008	system process	5.310166e-7
GO:0032094	response to food	5.839998e-7
GO:0019370	leukotriene biosynthetic process	6.565011e-7
GO:0050855	regulation of B cell receptor signaling pathway	7.413132e-7
GO:0051234	establishment of localization	7.441225e-7
GO:0001915	negative regulation of T cell mediated cytotoxicity	9.342441e-7
GO:0045619	regulation of lymphocyte differentiation	1.034285e-6
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	1.047356e-6
GO:0046456	icosanoid biosynthetic process	1.064143e-6
GO:0050870	positive regulation of T cell activation	1.281677e-6
GO:0050930	induction of positive chemotaxis	1.403572e-6
GO:0048807	female genitalia morphogenesis	1.440823e-6
GO:0060572	morphogenesis of an epithelial bud	1.474584e-6
GO:0032074	negative regulation of nuclease activity	1.629844e-6
GO:0046394	carboxylic acid biosynthetic process	1.726063e-6
GO:0050727	regulation of inflammatory response	1.789549e-6
GO:0050867	positive regulation of cell activation	2.002320e-6
GO:0001960	negative regulation of cytokine-mediated signaling pathway	2.047311e-6
GO:0006810	transport	2.060264e-6
GO:0045653	negative regulation of megakaryocyte differentiation	2.111051e-6
GO:0033275	actin-myosin filament sliding	2.176939e-6
GO:0003012	muscle system process	2.203108e-6
GO:0006636	unsaturated fatty acid biosynthetic process	2.381962e-6
GO:0000238	zygotene	2.462216e-6
GO:0034113	heterotypic cell-cell adhesion	2.799523e-6
GO:0007155	cell adhesion	2.969686e-6
GO:0001959	regulation of cytokine-mediated signaling pathway	3.023538e-6
GO:0048519	negative regulation of biological process	3.148490e-6
GO:0016310	phosphorylation	3.235205e-6
GO:0045580	regulation of T cell differentiation	3.446597e-6
GO:0044281	small molecule metabolic process	3.489397e-6
GO:0010941	regulation of cell death	3.635881e-6
GO:0048583	regulation of response to stimulus	3.755914e-6
GO:0008057	eye pigment granule organization	4.436310e-6
GO:0040018	positive regulation of multicellular organism growth	4.526180e-6
GO:0002696	positive regulation of leukocyte activation	4.536600e-6
GO:0045747	positive regulation of Notch signaling pathway	4.588435e-6
GO:0006200	ATP catabolic process	5.057703e-6
GO:0008152	metabolic process	5.277546e-6
GO:0007026	negative regulation of microtubule depolymerization	5.319925e-6
GO:0022610	biological adhesion	5.388054e-6
GO:0002252	immune effector process	5.399446e-6
GO:0045940	positive regulation of steroid metabolic process	5.508860e-6
GO:0060759	regulation of response to cytokine stimulus	5.577250e-6
GO:0050863	regulation of T cell activation	5.662611e-6
GO:2000107	negative regulation of leukocyte apoptosis	5.759459e-6
GO:0044283	small molecule biosynthetic process	5.995548e-6
GO:0007159	leukocyte cell-cell adhesion	6.141329e-6
GO:0006954	inflammatory response	6.677107e-6
GO:0016042	lipid catabolic process	6.769180e-6
GO:0002710	negative regulation of T cell mediated immunity	6.995125e-6
GO:0031114	regulation of microtubule depolymerization	7.014018e-6
GO:0006468	protein phosphorylation	7.209419e-6
GO:0070252	actin-mediated cell contraction	7.483542e-6
GO:0050852	T cell receptor signaling pathway	7.678590e-6
GO:0002700	regulation of production of molecular mediator of immune response	8.192183e-6
GO:0010627	regulation of intracellular protein kinase cascade	8.954983e-6
GO:0006959	humoral immune response	9.273378e-6
GO:0050854	regulation of antigen receptor-mediated signaling pathway	9.339018e-6
GO:0016265	death	9.413301e-6
GO:0051249	regulation of lymphocyte activation	9.555421e-6
GO:0030888	regulation of B cell proliferation	9.838061e-6
GO:0050927	positive regulation of positive chemotaxis	9.929277e-6
GO:0043901	negative regulation of multi-organism process	9.993654e-6
GO:0000245	spliceosome assembly	1.045018e-5
GO:0008219	cell death	1.173333e-5
GO:0040014	regulation of multicellular organism growth	1.198186e-5
GO:0043383	negative T cell selection	1.216178e-5
GO:0030540	female genitalia development	1.222213e-5
GO:0050790	regulation of catalytic activity	1.227897e-5
GO:0006928	cellular component movement	1.232386e-5
GO:0051241	negative regulation of multicellular organismal process	1.255159e-5
GO:0009410	response to xenobiotic stimulus	1.354372e-5
GO:0043067	regulation of programmed cell death	1.359238e-5
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	1.396446e-5
GO:0043086	negative regulation of catalytic activity	1.405201e-5
GO:0019098	reproductive behavior	1.434596e-5
GO:0070663	regulation of leukocyte proliferation	1.633733e-5
GO:0006691	leukotriene metabolic process	1.633866e-5
GO:0045582	positive regulation of T cell differentiation	1.663472e-5
GO:0002540	leukotriene production involved in inflammatory response	1.826351e-5
GO:0030049	muscle filament sliding	1.844712e-5
GO:0007275	multicellular organismal development	1.859402e-5
GO:0006435	threonyl-tRNA aminoacylation	1.876048e-5
GO:0023052	signaling	1.897645e-5
GO:0032944	regulation of mononuclear cell proliferation	1.928251e-5
GO:0051704	multi-organism process	1.936768e-5
GO:0002067	glandular epithelial cell differentiation	2.046392e-5
GO:0050670	regulation of lymphocyte proliferation	2.120350e-5
GO:0060594	mammary gland specification	2.131209e-5
GO:0007165	signal transduction	2.185728e-5
GO:0042102	positive regulation of T cell proliferation	2.207193e-5
GO:0051716	cellular response to stimulus	2.250667e-5
GO:0032946	positive regulation of mononuclear cell proliferation	2.273618e-5
GO:0016998	cell wall macromolecule catabolic process	2.409596e-5
GO:0070665	positive regulation of leukocyte proliferation	2.471561e-5
GO:0010817	regulation of hormone levels	2.512822e-5
GO:0042981	regulation of apoptosis	2.516446e-5
GO:0050671	positive regulation of lymphocyte proliferation	2.517732e-5
GO:0050926	regulation of positive chemotaxis	2.558093e-5
GO:0022612	gland morphogenesis	2.643352e-5
GO:0051251	positive regulation of lymphocyte activation	2.665176e-5
GO:0016337	cell-cell adhesion	2.688380e-5
GO:0032675	regulation of interleukin-6 production	2.701692e-5
GO:0006376	mRNA splice site selection	2.946113e-5
GO:0043542	endothelial cell migration	3.049123e-5
GO:2000974	negative regulation of pro-B cell differentiation	3.092790e-5
GO:0042628	mating plug formation	3.105801e-5
GO:0046635	positive regulation of alpha-beta T cell activation	3.183220e-5
GO:0090238	positive regulation of arachidonic acid secretion	3.223542e-5
GO:0043476	pigment accumulation	3.260118e-5
GO:0009956	radial pattern formation	3.260118e-5
GO:0050778	positive regulation of immune response	3.406006e-5
GO:0043242	negative regulation of protein complex disassembly	3.551777e-5
GO:0002820	negative regulation of adaptive immune response	3.572194e-5
GO:0021954	central nervous system neuron development	3.618378e-5
GO:0016477	cell migration	3.655928e-5
GO:0032502	developmental process	3.764553e-5
GO:0045658	regulation of neutrophil differentiation	3.772554e-5
GO:0019724	B cell mediated immunity	3.964632e-5
GO:0019853	L-ascorbic acid biosynthetic process	4.094138e-5
GO:0007219	Notch signaling pathway	4.107984e-5
GO:0007522	visceral muscle development	4.400745e-5
GO:0008593	regulation of Notch signaling pathway	4.487410e-5
GO:0046627	negative regulation of insulin receptor signaling pathway	4.602166e-5
GO:0032890	regulation of organic acid transport	4.760051e-5
GO:0042640	anagen	4.820969e-5
GO:0045060	negative thymic T cell selection	4.852295e-5
GO:0060197	cloacal septation	4.887347e-5
GO:0009605	response to external stimulus	4.913339e-5
GO:0006811	ion transport	5.122848e-5
GO:0016064	immunoglobulin mediated immune response	5.496533e-5
GO:0045926	negative regulation of growth	5.602382e-5
GO:0015669	gas transport	5.631000e-5
GO:0019538	protein metabolic process	5.815322e-5
GO:0010447	response to acidity	5.869777e-5
GO:0046034	ATP metabolic process	5.941057e-5
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	6.108518e-5
GO:0032652	regulation of interleukin-1 production	6.227666e-5
GO:0006796	phosphate-containing compound metabolic process	6.257354e-5
GO:0090270	regulation of fibroblast growth factor production	6.578257e-5
GO:0007499	ectoderm and mesoderm interaction	6.578257e-5
GO:0035385	Roundabout signaling pathway	6.708092e-5
GO:0050707	regulation of cytokine secretion	6.983033e-5
GO:0060529	squamous basal epithelial stem cell differentiation involved in prostate gland acinus development	8.174457e-5
GO:0050821	protein stabilization	8.569104e-5
GO:0050925	negative regulation of negative chemotaxis	8.678935e-5
GO:0006955	immune response	8.728207e-5
GO:0021539	subthalamus development	8.826249e-5
GO:0046634	regulation of alpha-beta T cell activation	8.997703e-5
GO:0007154	cell communication	9.291012e-5
GO:0010939	regulation of necrotic cell death	9.401226e-5
GO:0030168	platelet activation	9.445499e-5
GO:0045087	innate immune response	9.817569e-5
GO:0045588	positive regulation of gamma-delta T cell differentiation	1.010413e-4
GO:0010942	positive regulation of cell death	1.040411e-4
GO:0045191	regulation of isotype switching	1.046482e-4
GO:0045621	positive regulation of lymphocyte differentiation	1.048732e-4
GO:0002922	positive regulation of humoral immune response	1.051453e-4
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	1.113827e-4
GO:0007517	muscle organ development	1.127406e-4
GO:0019637	organophosphate metabolic process	1.142050e-4
GO:0060048	cardiac muscle contraction	1.150795e-4
GO:0042060	wound healing	1.155741e-4
GO:0007010	cytoskeleton organization	1.169757e-4
GO:0006644	phospholipid metabolic process	1.193854e-4
GO:0051024	positive regulation of immunoglobulin secretion	1.225056e-4
GO:0032651	regulation of interleukin-1 beta production	1.283257e-4
GO:0060537	muscle tissue development	1.299453e-4
GO:0008207	C21-steroid hormone metabolic process	1.305788e-4
GO:0040008	regulation of growth	1.318194e-4
GO:0035025	positive regulation of Rho protein signal transduction	1.427190e-4
GO:0051240	positive regulation of multicellular organismal process	1.432366e-4
GO:0044238	primary metabolic process	1.444327e-4
GO:0002637	regulation of immunoglobulin production	1.450233e-4
GO:0046641	positive regulation of alpha-beta T cell proliferation	1.470109e-4
GO:0009056	catabolic process	1.482239e-4
GO:0032103	positive regulation of response to external stimulus	1.534620e-4
GO:0031620	regulation of fever generation	1.541163e-4
GO:0031111	negative regulation of microtubule polymerization or depolymerization	1.592945e-4
GO:0007512	adult heart development	1.602264e-4
GO:0050901	leukocyte tethering or rolling	1.622322e-4
GO:0045665	negative regulation of neuron differentiation	1.655147e-4
GO:0033628	regulation of cell adhesion mediated by integrin	1.676522e-4
GO:0046626	regulation of insulin receptor signaling pathway	1.704600e-4
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	1.711831e-4
GO:0051023	regulation of immunoglobulin secretion	1.736285e-4
GO:0046877	regulation of saliva secretion	1.745039e-4
GO:0060571	morphogenesis of an epithelial fold	1.752736e-4
GO:0043244	regulation of protein complex disassembly	1.795963e-4
GO:0006805	xenobiotic metabolic process	1.819298e-4
GO:0060443	mammary gland morphogenesis	1.839703e-4
GO:0070229	negative regulation of lymphocyte apoptosis	1.844241e-4
GO:0022410	circadian sleep/wake cycle process	1.865951e-4
GO:0021953	central nervous system neuron differentiation	1.869686e-4
GO:0051282	regulation of sequestering of calcium ion	1.873964e-4
GO:0048856	anatomical structure development	1.897392e-4
GO:0051043	regulation of membrane protein ectodomain proteolysis	1.908243e-4
GO:0002065	columnar/cuboidal epithelial cell differentiation	1.922719e-4
GO:0060992	response to fungicide	1.990073e-4
GO:0007596	blood coagulation	1.998835e-4
GO:0002275	myeloid cell activation involved in immune response	2.002081e-4
GO:0042745	circadian sleep/wake cycle	2.210794e-4
GO:0034375	high-density lipoprotein particle remodeling	2.319264e-4
GO:0002026	regulation of the force of heart contraction	2.339090e-4
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	2.348488e-4
GO:0070368	positive regulation of hepatocyte differentiation	2.396989e-4
GO:0002237	response to molecule of bacterial origin	2.422707e-4
GO:0007186	G-protein coupled receptor protein signaling pathway	2.431692e-4
GO:0050864	regulation of B cell activation	2.438086e-4
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	2.450444e-4
GO:0048523	negative regulation of cellular process	2.473124e-4
GO:0007033	vacuole organization	2.474035e-4
GO:0043068	positive regulation of programmed cell death	2.485796e-4
GO:0031329	regulation of cellular catabolic process	2.535185e-4
GO:0001993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine	2.555310e-4
GO:0032844	regulation of homeostatic process	2.568820e-4
GO:0000187	activation of MAPK activity	2.583338e-4
GO:0045830	positive regulation of isotype switching	2.596601e-4
GO:0002740	negative regulation of cytokine secretion involved in immune response	2.642948e-4
GO:0042445	hormone metabolic process	2.676615e-4
GO:2000193	positive regulation of fatty acid transport	2.737455e-4
GO:0060047	heart contraction	2.738221e-4
GO:0009636	response to toxin	2.823840e-4
GO:0007599	hemostasis	2.845313e-4
GO:0061077	chaperone-mediated protein folding	2.877692e-4
GO:0043065	positive regulation of apoptosis	2.883581e-4
GO:0046164	alcohol catabolic process	2.884438e-4
GO:0008202	steroid metabolic process	2.966432e-4
GO:0006690	icosanoid metabolic process	3.002017e-4
GO:0007172	signal complex assembly	3.036295e-4
GO:0045834	positive regulation of lipid metabolic process	3.043338e-4
GO:0060661	submandibular salivary gland formation	3.049231e-4
GO:0061115	lung proximal/distal axis specification	3.049231e-4
GO:0070352	positive regulation of white fat cell proliferation	3.049231e-4
GO:0070075	tear secretion	3.049231e-4
GO:0060879	semicircular canal fusion	3.049231e-4
GO:0060496	mesenchymal-epithelial cell signaling involved in lung development	3.049231e-4
GO:0050677	positive regulation of urothelial cell proliferation	3.049231e-4
GO:0050674	urothelial cell proliferation	3.049231e-4
GO:0060436	bronchiole morphogenesis	3.049231e-4
GO:0002376	immune system process	3.191171e-4
GO:0048869	cellular developmental process	3.231704e-4
GO:0002739	regulation of cytokine secretion involved in immune response	3.273905e-4
GO:0050877	neurological system process	3.416145e-4
GO:0055114	oxidation-reduction process	3.478633e-4
GO:0051964	negative regulation of synapse assembly	3.494359e-4
GO:0019511	peptidyl-proline hydroxylation	3.494359e-4
GO:0007217	tachykinin receptor signaling pathway	3.494359e-4
GO:0033690	positive regulation of osteoblast proliferation	3.569965e-4
GO:0060648	mammary gland bud morphogenesis	3.606950e-4
GO:0070527	platelet aggregation	3.616535e-4
GO:0070366	regulation of hepatocyte differentiation	3.616535e-4
GO:0006457	protein folding	3.776834e-4
GO:0032496	response to lipopolysaccharide	3.840217e-4
GO:0060548	negative regulation of cell death	3.881604e-4
GO:0044242	cellular lipid catabolic process	3.902172e-4
GO:0008015	blood circulation	3.981341e-4
GO:0051977	lysophospholipid transport	4.008803e-4
GO:0001942	hair follicle development	4.036528e-4
GO:0080134	regulation of response to stress	4.096370e-4
GO:0006957	complement activation, alternative pathway	4.206558e-4
GO:0006915	apoptosis	4.255406e-4
GO:0006167	AMP biosynthetic process	4.301830e-4
GO:0016198	axon choice point recognition	4.306515e-4
GO:0046640	regulation of alpha-beta T cell proliferation	4.339773e-4
GO:0003229	ventricular cardiac muscle tissue development	4.376452e-4
GO:0060915	mesenchymal cell differentiation involved in lung development	4.399316e-4
GO:0060667	branch elongation involved in salivary gland morphogenesis	4.399316e-4
GO:0060615	mammary gland bud formation	4.399316e-4
GO:0060595	fibroblast growth factor receptor signaling pathway involved in mammary gland specification	4.399316e-4
GO:0046341	CDP-diacylglycerol metabolic process	4.454950e-4
GO:0030154	cell differentiation	4.462538e-4
GO:0048589	developmental growth	4.481131e-4
GO:0014807	regulation of somitogenesis	4.557162e-4
GO:0003270	Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation	4.557162e-4
GO:0032463	negative regulation of protein homooligomerization	4.610331e-4
GO:0030889	negative regulation of B cell proliferation	4.623664e-4
GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine	4.641356e-4
GO:0042135	neurotransmitter catabolic process	4.656647e-4
GO:0007268	synaptic transmission	4.661948e-4
GO:0006816	calcium ion transport	4.702186e-4
GO:0050878	regulation of body fluid levels	4.913550e-4
GO:0014706	striated muscle tissue development	4.920496e-4
GO:0048513	organ development	4.981483e-4
GO:0031657	regulation of cyclin-dependent protein kinase activity involved in G1/S	4.990507e-4
GO:0032892	positive regulation of organic acid transport	5.056248e-4
GO:0006953	acute-phase response	5.163628e-4
GO:0051952	regulation of amine transport	5.188558e-4
GO:0006436	tryptophanyl-tRNA aminoacylation	5.225389e-4
GO:0050704	regulation of interleukin-1 secretion	5.331901e-4
GO:0009888	tissue development	5.504988e-4
GO:0042404	thyroid hormone catabolic process	5.581409e-4
GO:0045577	regulation of B cell differentiation	5.625830e-4
GO:0009894	regulation of catabolic process	5.626615e-4
GO:0071287	cellular response to manganese ion	5.678570e-4
GO:0051961	negative regulation of nervous system development	5.678570e-4
GO:0051338	regulation of transferase activity	5.704498e-4
GO:0001738	morphogenesis of a polarized epithelium	5.764645e-4
GO:0002642	positive regulation of immunoglobulin biosynthetic process	5.831106e-4
GO:0055065	metal ion homeostasis	5.833331e-4
GO:0002443	leukocyte mediated immunity	5.843543e-4
GO:0042364	water-soluble vitamin biosynthetic process	5.860427e-4
GO:0042633	hair cycle	5.874663e-4
GO:0032755	positive regulation of interleukin-6 production	5.990550e-4
GO:0012501	programmed cell death	6.032350e-4
GO:0045357	regulation of interferon-beta biosynthetic process	6.032717e-4
GO:0031659	positive regulation of cyclin-dependent protein kinase activity involved in G1/S	6.077231e-4
GO:0042938	dipeptide transport	6.106667e-4
GO:0045061	thymic T cell selection	6.109822e-4
GO:0002526	acute inflammatory response	6.258393e-4
GO:0044057	regulation of system process	6.483048e-4
GO:0050706	regulation of interleukin-1 beta secretion	6.529923e-4
GO:0048870	cell motility	6.617781e-4
GO:0050709	negative regulation of protein secretion	6.627258e-4
GO:0051209	release of sequestered calcium ion into cytosol	6.638664e-4
GO:0035644	phosphoanandamide dephosphorylation	6.676685e-4
GO:0043069	negative regulation of programmed cell death	6.727349e-4
GO:0010893	positive regulation of steroid biosynthetic process	6.819816e-4
GO:0042129	regulation of T cell proliferation	6.863016e-4
GO:0044058	regulation of digestive system process	6.872983e-4
GO:0002281	macrophage activation involved in immune response	6.893392e-4
GO:0044092	negative regulation of molecular function	6.910901e-4
GO:2000466	negative regulation of glycogen (starch) synthase activity	7.010195e-4
GO:0042891	antibiotic transport	7.010195e-4
GO:0006925	inflammatory cell apoptosis	7.010195e-4
GO:0040011	locomotion	7.071213e-4
GO:0030859	polarized epithelial cell differentiation	7.158957e-4
GO:0070684	seminal clot liquefaction	7.213068e-4
GO:0051932	synaptic transmission, GABAergic	7.213068e-4
GO:0048747	muscle fiber development	7.213769e-4
GO:0032495	response to muramyl dipeptide	7.225824e-4
GO:0050869	negative regulation of B cell activation	7.234524e-4
GO:0031640	killing of cells of other organism	7.258492e-4
GO:0050830	defense response to Gram-positive bacterium	7.283401e-4
GO:0010033	response to organic substance	7.310380e-4
GO:0050684	regulation of mRNA processing	7.319944e-4
GO:0048518	positive regulation of biological process	7.335235e-4
GO:0007618	mating	7.358779e-4
GO:0007320	insemination	7.770109e-4
GO:0042104	positive regulation of activated T cell proliferation	8.083301e-4
GO:0002902	regulation of B cell apoptosis	8.140255e-4
GO:0000398	nuclear mRNA splicing, via spliceosome	8.145755e-4
GO:0060558	regulation of calcidiol 1-monooxygenase activity	8.157338e-4
GO:0009395	phospholipid catabolic process	8.171065e-4
GO:0003218	cardiac left ventricle formation	8.251453e-4
GO:0043066	negative regulation of apoptosis	8.317079e-4
GO:0060557	positive regulation of vitamin D biosynthetic process	8.478175e-4
GO:0070228	regulation of lymphocyte apoptosis	8.478675e-4
GO:0045187	regulation of circadian sleep/wake cycle, sleep	8.541206e-4
GO:0008624	induction of apoptosis by extracellular signals	8.695855e-4
GO:0042219	cellular modified amino acid catabolic process	8.838453e-4
GO:0032781	positive regulation of ATPase activity	8.941872e-4
GO:0042446	hormone biosynthetic process	9.119463e-4
GO:0050795	regulation of behavior	9.229619e-4
GO:0009615	response to virus	9.296633e-4
GO:0051659	maintenance of mitochondrion location	9.325521e-4
GO:0050729	positive regulation of inflammatory response	9.326125e-4
GO:0022038	corpus callosum development	9.386960e-4
GO:0000375	RNA splicing, via transesterification reactions	9.460732e-4
GO:0070307	lens fiber cell development	9.480313e-4
GO:0072233	metanephric thick ascending limb development	9.568324e-4
GO:0072218	metanephric ascending thin limb development	9.568324e-4
GO:0003013	circulatory system process	9.996149e-4
GO:0046579	positive regulation of Ras protein signal transduction	1.001112e-3
GO:0071840	cellular component organization or biogenesis	1.004591e-3
GO:0002757	immune response-activating signal transduction	1.014835e-3
GO:0051788	response to misfolded protein	1.018469e-3
GO:0015893	drug transport	1.022090e-3
GO:0042402	cellular biogenic amine catabolic process	1.023597e-3
GO:0048731	system development	1.024280e-3
GO:0070346	positive regulation of fat cell proliferation	1.030096e-3
GO:0046475	glycerophospholipid catabolic process	1.030096e-3
GO:0006597	spermine biosynthetic process	1.034904e-3
GO:0032078	negative regulation of endodeoxyribonuclease activity	1.034904e-3
GO:0051025	negative regulation of immunoglobulin secretion	1.034904e-3
GO:0006922	cleavage of lamin	1.034904e-3
GO:0060164	regulation of timing of neuron differentiation	1.035297e-3
GO:0051348	negative regulation of transferase activity	1.054595e-3
GO:0071773	cellular response to BMP stimulus	1.064342e-3
GO:0060690	epithelial cell differentiation involved in salivary gland development	1.067297e-3
GO:0048711	positive regulation of astrocyte differentiation	1.074931e-3
GO:0060592	mammary gland formation	1.082880e-3
GO:0002764	immune response-regulating signaling pathway	1.101108e-3
GO:0034384	high-density lipoprotein particle clearance	1.102673e-3
GO:0048584	positive regulation of response to stimulus	1.111127e-3
GO:0045616	regulation of keratinocyte differentiation	1.124860e-3
GO:0007600	sensory perception	1.128392e-3
GO:0046033	AMP metabolic process	1.128825e-3
GO:0018149	peptide cross-linking	1.150397e-3
GO:0031069	hair follicle morphogenesis	1.161288e-3
GO:0048692	negative regulation of axon extension involved in regeneration	1.164664e-3
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	1.164664e-3
GO:0018158	protein oxidation	1.164664e-3
GO:0000073	spindle pole body separation	1.164664e-3
GO:0022417	protein maturation by protein folding	1.164664e-3
GO:0032692	negative regulation of interleukin-1 production	1.168337e-3
GO:0055085	transmembrane transport	1.187823e-3
GO:0009653	anatomical structure morphogenesis	1.227331e-3
GO:0045911	positive regulation of DNA recombination	1.227893e-3
GO:0043508	negative regulation of JUN kinase activity	1.228875e-3
GO:0045124	regulation of bone resorption	1.234872e-3
GO:0033081	regulation of T cell differentiation in thymus	1.239533e-3
GO:0051883	killing of cells in other organism involved in symbiotic interaction	1.253328e-3
GO:0002903	negative regulation of B cell apoptosis	1.260614e-3
GO:0030890	positive regulation of B cell proliferation	1.301223e-3
GO:0072017	distal tubule development	1.324199e-3
GO:0001555	oocyte growth	1.327014e-3
GO:0007266	Rho protein signal transduction	1.328198e-3
GO:0031622	positive regulation of fever generation	1.335380e-3
GO:0019852	L-ascorbic acid metabolic process	1.338956e-3
GO:0040007	growth	1.339122e-3
GO:0000072	M phase specific microtubule process	1.343699e-3
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	1.361222e-3
GO:0008299	isoprenoid biosynthetic process	1.364016e-3
GO:0010872	regulation of cholesterol esterification	1.369413e-3
GO:0035588	G-protein coupled purinergic receptor signaling pathway	1.373276e-3
GO:0048541	Peyer's patch development	1.387057e-3
GO:0060513	prostatic bud formation	1.409523e-3
GO:0070493	thrombin receptor signaling pathway	1.436997e-3
GO:0060555	induction of necroptosis by extracellular signals	1.436997e-3
GO:0003171	atrioventricular valve development	1.437357e-3
GO:0032691	negative regulation of interleukin-1 beta production	1.440478e-3
GO:0014823	response to activity	1.456314e-3
GO:0071875	adrenergic receptor signaling pathway	1.464172e-3
GO:0050881	musculoskeletal movement	1.482702e-3
GO:0010873	positive regulation of cholesterol esterification	1.497877e-3
GO:2000191	regulation of fatty acid transport	1.512546e-3
GO:0001937	negative regulation of endothelial cell proliferation	1.520049e-3
GO:0051341	regulation of oxidoreductase activity	1.529712e-3
GO:0055080	cation homeostasis	1.546362e-3
GO:0006812	cation transport	1.589688e-3
GO:0051657	maintenance of organelle location	1.599746e-3
GO:0034638	phosphatidylcholine catabolic process	1.619648e-3
GO:0034754	cellular hormone metabolic process	1.625940e-3
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	1.642343e-3
GO:0034109	homotypic cell-cell adhesion	1.651619e-3
GO:0048630	skeletal muscle tissue growth	1.689765e-3
GO:0030644	cellular chloride ion homeostasis	1.689765e-3
GO:0009110	vitamin biosynthetic process	1.694086e-3
GO:0033674	positive regulation of kinase activity	1.694199e-3
GO:0051494	negative regulation of cytoskeleton organization	1.712574e-3
GO:0016199	axon midline choice point recognition	1.715682e-3
GO:0050920	regulation of chemotaxis	1.728939e-3
GO:0045664	regulation of neuron differentiation	1.745564e-3
GO:0006581	acetylcholine catabolic process	1.749440e-3
GO:0007417	central nervous system development	1.780178e-3
GO:0034103	regulation of tissue remodeling	1.806160e-3
GO:0008306	associative learning	1.807734e-3
GO:0002649	regulation of tolerance induction to self antigen	1.813228e-3
GO:0030048	actin filament-based movement	1.815866e-3
GO:0050433	regulation of catecholamine secretion	1.836198e-3
GO:0033622	integrin activation	1.851863e-3
GO:0045358	negative regulation of interferon-beta biosynthetic process	1.851863e-3