Novel motif:156

name:	motif156_ACTGTAGGACMT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0009589	detection of UV	1.050573e-16
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	1.050573e-16
GO:0051932	synaptic transmission, GABAergic	3.386067e-16
GO:0070541	response to platinum ion	4.708101e-11
GO:0046501	protoporphyrinogen IX metabolic process	2.081235e-10
GO:0021771	lateral geniculate nucleus development	1.398719e-9
GO:0048513	organ development	2.837532e-9
GO:0048769	sarcomerogenesis	2.274643e-8
GO:0006941	striated muscle contraction	2.533357e-8
GO:0055013	cardiac muscle cell development	4.400299e-8
GO:0034436	glycoprotein transport	6.841598e-8
GO:0009720	detection of hormone stimulus	6.841598e-8
GO:0050878	regulation of body fluid levels	9.125473e-8
GO:0009726	detection of endogenous stimulus	9.672974e-8
GO:0030241	skeletal muscle myosin thick filament assembly	1.612854e-7
GO:0001906	cell killing	1.829453e-7
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	1.899696e-7
GO:0048731	system development	2.058605e-7
GO:0042060	wound healing	2.111094e-7
GO:0006527	arginine catabolic process	2.433631e-7
GO:0007076	mitotic chromosome condensation	2.915502e-7
GO:0031284	positive regulation of guanylate cyclase activity	4.605275e-7
GO:0007599	hemostasis	4.824092e-7
GO:0030240	skeletal muscle thin filament assembly	5.287503e-7
GO:0019046	reactivation of latent virus	5.584346e-7
GO:0007596	blood coagulation	5.763845e-7
GO:0048739	cardiac muscle fiber development	6.163500e-7
GO:0051897	positive regulation of protein kinase B signaling cascade	7.164313e-7
GO:0010288	response to lead ion	7.338574e-7
GO:0038007	netrin-activated signaling pathway	9.394558e-7
GO:0032501	multicellular organismal process	1.008131e-6
GO:0046541	saliva secretion	1.017217e-6
GO:0031444	slow-twitch skeletal muscle fiber contraction	1.017217e-6
GO:0051896	regulation of protein kinase B signaling cascade	1.050193e-6
GO:0060084	synaptic transmission involved in micturition	1.216706e-6
GO:0006783	heme biosynthetic process	1.294486e-6
GO:0031640	killing of cells of other organism	1.319876e-6
GO:0051146	striated muscle cell differentiation	1.466638e-6
GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.799052e-6
GO:0070838	divalent metal ion transport	1.832981e-6
GO:0030048	actin filament-based movement	2.029646e-6
GO:0019538	protein metabolic process	2.069434e-6
GO:0006816	calcium ion transport	2.150080e-6
GO:0072511	divalent inorganic cation transport	2.175094e-6
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	2.324040e-6
GO:0006525	arginine metabolic process	2.766498e-6
GO:0002576	platelet degranulation	2.799405e-6
GO:0042692	muscle cell differentiation	2.920792e-6
GO:0030168	platelet activation	2.938829e-6
GO:0033577	protein glycosylation in endoplasmic reticulum	3.416194e-6
GO:0048840	otolith development	3.426996e-6
GO:0006950	response to stress	3.447854e-6
GO:0070588	calcium ion transmembrane transport	3.933621e-6
GO:0014866	skeletal myofibril assembly	4.004331e-6
GO:0007275	multicellular organismal development	4.042492e-6
GO:0010038	response to metal ion	4.400170e-6
GO:0070482	response to oxygen levels	4.734354e-6
GO:0007520	myoblast fusion	5.004333e-6
GO:0018149	peptide cross-linking	5.597816e-6
GO:0055003	cardiac myofibril assembly	5.955901e-6
GO:0031282	regulation of guanylate cyclase activity	6.214021e-6
GO:0001974	blood vessel remodeling	6.605821e-6
GO:0055099	response to high density lipoprotein particle stimulus	6.607728e-6
GO:0001666	response to hypoxia	6.713829e-6
GO:0030187	melatonin biosynthetic process	7.951023e-6
GO:0042026	protein refolding	9.397521e-6
GO:0032502	developmental process	9.509061e-6
GO:2000304	positive regulation of ceramide biosynthetic process	9.885103e-6
GO:0055094	response to lipoprotein stimulus	1.115139e-5
GO:0000070	mitotic sister chromatid segregation	1.134175e-5
GO:0051597	response to methylmercury	1.182144e-5
GO:0043537	negative regulation of blood vessel endothelial cell migration	1.298462e-5
GO:2000303	regulation of ceramide biosynthetic process	1.514058e-5
GO:0006508	proteolysis	1.620127e-5
GO:0001542	ovulation from ovarian follicle	1.646005e-5
GO:0070104	negative regulation of interleukin-6-mediated signaling pathway	1.675516e-5
GO:0000819	sister chromatid segregation	1.760991e-5
GO:0097006	regulation of plasma lipoprotein particle levels	1.898505e-5
GO:0030278	regulation of ossification	1.966583e-5
GO:0030001	metal ion transport	1.966761e-5
GO:0045759	negative regulation of action potential	2.008727e-5
GO:0006936	muscle contraction	2.382699e-5
GO:0043316	cytotoxic T cell degranulation	2.540090e-5
GO:0044087	regulation of cellular component biogenesis	2.551997e-5
GO:0018160	peptidyl-pyrromethane cofactor linkage	2.696997e-5
GO:0019220	regulation of phosphate metabolic process	2.748702e-5
GO:0030049	muscle filament sliding	2.755895e-5
GO:0006949	syncytium formation	2.772711e-5
GO:0032147	activation of protein kinase activity	2.945148e-5
GO:0010885	regulation of cholesterol storage	2.987307e-5
GO:0032268	regulation of cellular protein metabolic process	3.095446e-5
GO:0042325	regulation of phosphorylation	3.116322e-5
GO:2000753	positive regulation of glucosylceramide catabolic process	3.151758e-5
GO:2000755	positive regulation of sphingomyelin catabolic process	3.151758e-5
GO:0070106	interleukin-27-mediated signaling pathway	3.236077e-5
GO:0048856	anatomical structure development	3.284628e-5
GO:0003012	muscle system process	3.344449e-5
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	3.370265e-5
GO:0032226	positive regulation of synaptic transmission, dopaminergic	3.400175e-5
GO:0045214	sarcomere organization	3.460833e-5
GO:0071103	DNA conformation change	3.480290e-5
GO:0070252	actin-mediated cell contraction	3.650559e-5
GO:0009887	organ morphogenesis	3.675923e-5
GO:0021562	vestibulocochlear nerve development	3.842863e-5
GO:0000279	M phase	4.041966e-5
GO:0010751	negative regulation of nitric oxide mediated signal transduction	4.213954e-5
GO:0043652	engulfment of apoptotic cell	4.213954e-5
GO:0010754	negative regulation of cGMP-mediated signaling	4.213954e-5
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	4.213954e-5
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	4.213954e-5
GO:0014902	myotube differentiation	4.445818e-5
GO:0006779	porphyrin-containing compound biosynthetic process	4.466165e-5
GO:0010883	regulation of lipid storage	4.677258e-5
GO:0048075	positive regulation of eye pigmentation	4.688825e-5
GO:0055007	cardiac muscle cell differentiation	4.771142e-5
GO:0042168	heme metabolic process	4.893512e-5
GO:0050673	epithelial cell proliferation	4.941711e-5
GO:0043353	enucleate erythrocyte differentiation	4.951652e-5
GO:0032891	negative regulation of organic acid transport	5.083355e-5
GO:0035914	skeletal muscle cell differentiation	5.201578e-5
GO:0009611	response to wounding	5.341072e-5
GO:0045766	positive regulation of angiogenesis	5.479333e-5
GO:0014706	striated muscle tissue development	5.566827e-5
GO:0000173	inactivation of MAPK activity involved in osmosensory signaling pathway	6.076096e-5
GO:0042053	regulation of dopamine metabolic process	6.298936e-5
GO:0032298	positive regulation of DNA-dependent DNA replication initiation	6.383551e-5
GO:0050928	negative regulation of positive chemotaxis	6.711415e-5
GO:0045542	positive regulation of cholesterol biosynthetic process	6.717886e-5
GO:0071803	positive regulation of podosome assembly	6.765107e-5
GO:0002544	chronic inflammatory response	6.830139e-5
GO:0031399	regulation of protein modification process	6.884798e-5
GO:0030154	cell differentiation	7.235863e-5
GO:0048747	muscle fiber development	7.270850e-5
GO:0006778	porphyrin-containing compound metabolic process	7.328880e-5
GO:0071549	cellular response to dexamethasone stimulus	7.429546e-5
GO:0042069	regulation of catecholamine metabolic process	7.429546e-5
GO:0007059	chromosome segregation	7.466702e-5
GO:0000045	autophagic vacuole assembly	7.602640e-5
GO:0002088	lens development in camera-type eye	7.757471e-5
GO:0002577	regulation of antigen processing and presentation	7.876840e-5
GO:2000377	regulation of reactive oxygen species metabolic process	7.887148e-5
GO:0048869	cellular developmental process	7.973306e-5
GO:0001963	synaptic transmission, dopaminergic	8.058401e-5
GO:0010035	response to inorganic substance	8.086459e-5
GO:0045187	regulation of circadian sleep/wake cycle, sleep	8.903211e-5
GO:0065008	regulation of biological quality	9.358452e-5
GO:0055008	cardiac muscle tissue morphogenesis	9.400611e-5
GO:0007256	activation of JNKK activity	9.483951e-5
GO:0015671	oxygen transport	1.020709e-4
GO:0048073	regulation of eye pigmentation	1.084229e-4
GO:0022410	circadian sleep/wake cycle process	1.101112e-4
GO:0030838	positive regulation of actin filament polymerization	1.160430e-4
GO:0009065	glutamine family amino acid catabolic process	1.168628e-4
GO:0033013	tetrapyrrole metabolic process	1.170641e-4
GO:0045577	regulation of B cell differentiation	1.185015e-4
GO:0010888	negative regulation of lipid storage	1.197485e-4
GO:0009653	anatomical structure morphogenesis	1.255013e-4
GO:0061048	negative regulation of branching involved in lung morphogenesis	1.255653e-4
GO:0045834	positive regulation of lipid metabolic process	1.287898e-4
GO:0042745	circadian sleep/wake cycle	1.353026e-4
GO:0060537	muscle tissue development	1.398339e-4
GO:0009636	response to toxin	1.410318e-4
GO:0007214	gamma-aminobutyric acid signaling pathway	1.426926e-4
GO:0007270	neuron-neuron synaptic transmission	1.481127e-4
GO:0090205	positive regulation of cholesterol metabolic process	1.610398e-4
GO:0034231	islet amyloid polypeptide processing	1.637466e-4
GO:0034230	enkephalin processing	1.637466e-4
GO:0006812	cation transport	1.690260e-4
GO:0001932	regulation of protein phosphorylation	1.722959e-4
GO:0007231	osmosensory signaling pathway	1.746473e-4
GO:0042752	regulation of circadian rhythm	1.785033e-4
GO:0050680	negative regulation of epithelial cell proliferation	1.822306e-4
GO:0000087	M phase of mitotic cell cycle	1.832345e-4
GO:0048512	circadian behavior	1.847344e-4
GO:0021631	optic nerve morphogenesis	1.885999e-4
GO:0050867	positive regulation of cell activation	1.898467e-4
GO:0035051	cardiac cell differentiation	1.971904e-4
GO:0071827	plasma lipoprotein particle organization	1.977166e-4
GO:0070103	regulation of interleukin-6-mediated signaling pathway	2.004961e-4
GO:0000186	activation of MAPKK activity	2.048589e-4
GO:0030218	erythrocyte differentiation	2.069664e-4
GO:0009888	tissue development	2.128337e-4
GO:0034379	very-low-density lipoprotein particle assembly	2.139053e-4
GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	2.141329e-4
GO:0070120	ciliary neurotrophic factor-mediated signaling pathway	2.374093e-4
GO:2000612	regulation of thyroid-stimulating hormone secretion	2.422010e-4
GO:0014740	negative regulation of muscle hyperplasia	2.422010e-4
GO:0014806	smooth muscle hyperplasia	2.422010e-4
GO:0010893	positive regulation of steroid biosynthetic process	2.426387e-4
GO:0055091	phospholipid homeostasis	2.429461e-4
GO:0008344	adult locomotory behavior	2.454559e-4
GO:0006323	DNA packaging	2.514109e-4
GO:0070102	interleukin-6-mediated signaling pathway	2.588843e-4
GO:0030186	melatonin metabolic process	2.618218e-4
GO:0070904	transepithelial L-ascorbic acid transport	2.826255e-4
GO:0042982	amyloid precursor protein metabolic process	2.954833e-4
GO:0051246	regulation of protein metabolic process	2.979419e-4
GO:0045667	regulation of osteoblast differentiation	3.002766e-4
GO:0007626	locomotory behavior	3.153611e-4
GO:0046889	positive regulation of lipid biosynthetic process	3.195992e-4
GO:0032368	regulation of lipid transport	3.234719e-4
GO:0043949	regulation of cAMP-mediated signaling	3.287078e-4
GO:0002344	B cell affinity maturation	3.316961e-4
GO:0010743	regulation of macrophage derived foam cell differentiation	3.321448e-4
GO:0050881	musculoskeletal movement	3.362601e-4
GO:0007067	mitosis	3.472671e-4
GO:0048568	embryonic organ development	3.530814e-4
GO:0060415	muscle tissue morphogenesis	3.617653e-4
GO:0030261	chromosome condensation	3.695806e-4
GO:0032914	positive regulation of transforming growth factor beta1 production	3.837460e-4
GO:0021554	optic nerve development	3.947959e-4
GO:0072278	metanephric comma-shaped body morphogenesis	4.060380e-4
GO:0007525	somatic muscle development	4.080222e-4
GO:0042312	regulation of vasodilation	4.169504e-4
GO:0055001	muscle cell development	4.176472e-4
GO:0051533	positive regulation of NFAT protein import into nucleus	4.205969e-4
GO:0010887	negative regulation of cholesterol storage	4.226364e-4
GO:0007622	rhythmic behavior	4.231924e-4
GO:0033144	negative regulation of steroid hormone receptor signaling pathway	4.238872e-4
GO:0070076	histone lysine demethylation	4.335677e-4
GO:0051895	negative regulation of focal adhesion assembly	4.335677e-4
GO:0014738	regulation of muscle hyperplasia	4.349392e-4
GO:0032613	interleukin-10 production	4.652388e-4
GO:0030970	retrograde protein transport, ER to cytosol	4.653632e-4
GO:0007423	sensory organ development	4.941699e-4
GO:0006887	exocytosis	5.073110e-4
GO:0006746	FADH2 metabolic process	5.077216e-4
GO:0051414	response to cortisol stimulus	5.141290e-4
GO:0000165	MAPKKK cascade	5.163939e-4
GO:0048285	organelle fission	5.223473e-4
GO:0032890	regulation of organic acid transport	5.325876e-4
GO:0050818	regulation of coagulation	5.400914e-4
GO:0042320	regulation of circadian sleep/wake cycle, REM sleep	5.662871e-4
GO:0014745	negative regulation of muscle adaptation	5.662871e-4
GO:0071548	response to dexamethasone stimulus	5.806125e-4
GO:0010763	positive regulation of fibroblast migration	5.890274e-4
GO:0051481	reduction of cytosolic calcium ion concentration	5.899759e-4
GO:0048729	tissue morphogenesis	6.020251e-4
GO:0043587	tongue morphogenesis	6.114943e-4
GO:0010757	negative regulation of plasminogen activation	6.166275e-4
GO:0030070	insulin processing	6.193375e-4
GO:0048671	negative regulation of collateral sprouting	6.487990e-4
GO:0043267	negative regulation of potassium ion transport	6.487990e-4
GO:0001649	osteoblast differentiation	6.598985e-4
GO:0015669	gas transport	6.655465e-4
GO:0002339	B cell selection	6.871397e-4
GO:0051592	response to calcium ion	6.901441e-4
GO:0050896	response to stimulus	6.953235e-4
GO:0010596	negative regulation of endothelial cell migration	6.967829e-4
GO:0045859	regulation of protein kinase activity	7.029622e-4
GO:0051918	negative regulation of fibrinolysis	7.142616e-4
GO:0007517	muscle organ development	7.283726e-4
GO:0007271	synaptic transmission, cholinergic	7.436207e-4
GO:0048644	muscle organ morphogenesis	7.440081e-4
GO:0043549	regulation of kinase activity	7.639186e-4
GO:0034101	erythrocyte homeostasis	7.665098e-4
GO:0060766	negative regulation of androgen receptor signaling pathway	7.877117e-4
GO:0030866	cortical actin cytoskeleton organization	7.923784e-4
GO:0030204	chondroitin sulfate metabolic process	7.923784e-4
GO:0001507	acetylcholine catabolic process in synaptic cleft	8.028377e-4
GO:0051338	regulation of transferase activity	8.071484e-4
GO:0030826	regulation of cGMP biosynthetic process	8.157783e-4
GO:0061084	negative regulation of protein refolding	8.163554e-4
GO:0035095	behavioral response to nicotine	8.163554e-4
GO:0032695	negative regulation of interleukin-12 production	8.415746e-4
GO:0023021	termination of signal transduction	8.768742e-4
GO:0032367	intracellular cholesterol transport	8.781959e-4
GO:0010755	regulation of plasminogen activation	8.976891e-4
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport	8.976891e-4
GO:0006891	intra-Golgi vesicle-mediated transport	9.437045e-4
GO:0060557	positive regulation of vitamin D biosynthetic process	9.514553e-4
GO:0022414	reproductive process	9.657818e-4
GO:0030865	cortical cytoskeleton organization	9.681043e-4
GO:0032402	melanosome transport	9.766771e-4
GO:0003009	skeletal muscle contraction	9.772890e-4
GO:0016236	macroautophagy	9.809999e-4
GO:0040008	regulation of growth	9.892876e-4
GO:0051917	regulation of fibrinolysis	1.019513e-3
GO:0015993	molecular hydrogen transport	1.023559e-3
GO:0008543	fibroblast growth factor receptor signaling pathway	1.025797e-3
GO:0070278	extracellular matrix constituent secretion	1.030385e-3
GO:0010260	organ senescence	1.030385e-3
GO:0060696	regulation of phospholipid catabolic process	1.030385e-3
GO:0033605	positive regulation of catecholamine secretion	1.039081e-3
GO:0045682	regulation of epidermis development	1.041067e-3
GO:0043535	regulation of blood vessel endothelial cell migration	1.072277e-3
GO:0046219	indolalkylamine biosynthetic process	1.080941e-3
GO:0048511	rhythmic process	1.086536e-3
GO:0002696	positive regulation of leukocyte activation	1.094235e-3
GO:0009582	detection of abiotic stimulus	1.111110e-3
GO:0044254	multicellular organismal protein catabolic process	1.113800e-3
GO:0000003	reproduction	1.125194e-3
GO:0010759	positive regulation of macrophage chemotaxis	1.177849e-3
GO:0030239	myofibril assembly	1.179364e-3
GO:0002089	lens morphogenesis in camera-type eye	1.190840e-3
GO:0032232	negative regulation of actin filament bundle assembly	1.222963e-3
GO:0072387	flavin adenine dinucleotide metabolic process	1.253731e-3
GO:0006642	triglyceride mobilization	1.253823e-3
GO:2000594	positive regulation of metanephric DCT cell differentiation	1.267415e-3
GO:0039003	pronephric field specification	1.267415e-3
GO:0072305	negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis	1.267415e-3
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	1.271603e-3
GO:0030832	regulation of actin filament length	1.272053e-3
GO:0030534	adult behavior	1.296612e-3
GO:0033603	positive regulation of dopamine secretion	1.298671e-3
GO:0060235	lens induction in camera-type eye	1.325022e-3
GO:0046685	response to arsenic-containing substance	1.383449e-3
GO:0010758	regulation of macrophage chemotaxis	1.383449e-3
GO:0017085	response to insecticide	1.383449e-3
GO:0002005	angiotensin catabolic process in blood	1.386610e-3
GO:0044268	multicellular organismal protein metabolic process	1.392295e-3
GO:0048861	leukemia inhibitory factor signaling pathway	1.405916e-3
GO:0009628	response to abiotic stimulus	1.448738e-3
GO:0006605	protein targeting	1.490366e-3
GO:0070318	positive regulation of G0 to G1 transition	1.494993e-3
GO:0071557	histone H3-K27 demethylation	1.494993e-3
GO:0048014	Tie receptor signaling pathway	1.494993e-3
GO:0035574	histone H4-K20 demethylation	1.494993e-3
GO:0022403	cell cycle phase	1.497730e-3
GO:0051904	pigment granule transport	1.507948e-3
GO:0071498	cellular response to fluid shear stress	1.579276e-3
GO:2001013	epithelial cell proliferation involve in renal tubule morphogenesis	1.579276e-3
GO:0032908	regulation of transforming growth factor beta1 production	1.586660e-3
GO:0046903	secretion	1.595742e-3
GO:0043320	natural killer cell degranulation	1.602847e-3
GO:0072003	kidney rudiment formation	1.629519e-3
GO:0021794	thalamus development	1.640526e-3
GO:0050654	chondroitin sulfate proteoglycan metabolic process	1.673907e-3
GO:0048024	regulation of nuclear mRNA splicing, via spliceosome	1.674773e-3
GO:0032026	response to magnesium ion	1.689992e-3
GO:0010872	regulation of cholesterol esterification	1.709967e-3
GO:0070316	regulation of G0 to G1 transition	1.715990e-3
GO:0033238	regulation of cellular amine metabolic process	1.721000e-3
GO:0009583	detection of light stimulus	1.736355e-3
GO:0043032	positive regulation of macrophage activation	1.765181e-3
GO:0007507	heart development	1.779307e-3
GO:0051346	negative regulation of hydrolase activity	1.782020e-3
GO:0072284	metanephric S-shaped body morphogenesis	1.793724e-3
GO:0019852	L-ascorbic acid metabolic process	1.793724e-3
GO:0071675	regulation of mononuclear cell migration	1.813635e-3
GO:0061061	muscle structure development	1.832060e-3
GO:0045764	positive regulation of cellular amino acid metabolic process	1.835127e-3
GO:0001775	cell activation	1.877102e-3
GO:0010927	cellular component assembly involved in morphogenesis	1.885777e-3
GO:0006911	phagocytosis, engulfment	1.904889e-3
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	1.918680e-3
GO:0007049	cell cycle	1.926199e-3
GO:0034405	response to fluid shear stress	1.955952e-3
GO:0031117	positive regulation of microtubule depolymerization	1.958674e-3
GO:0032237	activation of store-operated calcium channel activity	1.974243e-3
GO:0010976	positive regulation of neuron projection development	2.012408e-3
GO:0002604	regulation of dendritic cell antigen processing and presentation	2.028622e-3
GO:0006606	protein import into nucleus	2.035295e-3
GO:0072160	nephron tubule epithelial cell differentiation	2.046717e-3
GO:0033240	positive regulation of cellular amine metabolic process	2.051683e-3
GO:0010955	negative regulation of protein processing	2.060741e-3
GO:0007258	JUN phosphorylation	2.062299e-3
GO:0032615	interleukin-12 production	2.088477e-3
GO:0019233	sensory perception of pain	2.110489e-3
GO:0032273	positive regulation of protein polymerization	2.110489e-3
GO:0072221	metanephric distal convoluted tubule development	2.121183e-3
GO:0032401	establishment of melanosome localization	2.176584e-3
GO:0005999	xylulose biosynthetic process	2.183392e-3
GO:0045727	positive regulation of translation	2.204398e-3
GO:0050670	regulation of lymphocyte proliferation	2.213585e-3
GO:0007628	adult walking behavior	2.241686e-3
GO:0006548	histidine catabolic process	2.256910e-3
GO:0016043	cellular component organization	2.277693e-3
GO:0042987	amyloid precursor protein catabolic process	2.307271e-3
GO:0032800	receptor biosynthetic process	2.359069e-3
GO:0050865	regulation of cell activation	2.372540e-3
GO:0022402	cell cycle process	2.376644e-3
GO:2000191	regulation of fatty acid transport	2.410895e-3
GO:0048793	pronephros development	2.439639e-3
GO:0002456	T cell mediated immunity	2.443922e-3
GO:0006464	protein modification process	2.473788e-3
GO:0071622	regulation of granulocyte chemotaxis	2.476370e-3
GO:0030071	regulation of mitotic metaphase/anaphase transition	2.483560e-3
GO:0008629	induction of apoptosis by intracellular signals	2.566108e-3
GO:0033235	positive regulation of protein sumoylation	2.586713e-3
GO:0051170	nuclear import	2.591032e-3
GO:0061333	renal tubule morphogenesis	2.599991e-3
GO:0045940	positive regulation of steroid metabolic process	2.602701e-3
GO:0030301	cholesterol transport	2.624415e-3
GO:0090218	positive regulation of lipid kinase activity	2.678794e-3
GO:0048670	regulation of collateral sprouting	2.701088e-3
GO:0032944	regulation of mononuclear cell proliferation	2.744432e-3
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	2.752352e-3
GO:0051234	establishment of localization	2.833351e-3
GO:0071636	positive regulation of transforming growth factor beta production	2.863743e-3
GO:0045579	positive regulation of B cell differentiation	2.891438e-3
GO:0007274	neuromuscular synaptic transmission	2.917690e-3
GO:0044344	cellular response to fibroblast growth factor stimulus	2.930816e-3
GO:0001990	regulation of systemic arterial blood pressure by hormone	2.998738e-3
GO:0071354	cellular response to interleukin-6	3.042042e-3
GO:0006810	transport	3.048794e-3
GO:0051347	positive regulation of transferase activity	3.050845e-3
GO:0060452	positive regulation of cardiac muscle contraction	3.081647e-3
GO:0051905	establishment of pigment granule localization	3.137451e-3
GO:0034220	ion transmembrane transport	3.156596e-3
GO:0042127	regulation of cell proliferation	3.159075e-3
GO:2000117	negative regulation of cysteine-type endopeptidase activity	3.216154e-3
GO:0071674	mononuclear cell migration	3.216154e-3
GO:0033674	positive regulation of kinase activity	3.306406e-3
GO:0015918	sterol transport	3.330538e-3
GO:0048738	cardiac muscle tissue development	3.366793e-3
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	3.533764e-3
GO:0000278	mitotic cell cycle	3.546827e-3
GO:0090066	regulation of anatomical structure size	3.558695e-3
GO:0060437	lung growth	3.573384e-3
GO:0018209	peptidyl-serine modification	3.598149e-3
GO:0050819	negative regulation of coagulation	3.657358e-3
GO:0060255	regulation of macromolecule metabolic process	3.661755e-3
GO:0071615	oxidative deethylation	3.669680e-3
GO:0070184	mitochondrial tyrosyl-tRNA aminoacylation	3.669680e-3
GO:0009403	toxin biosynthetic process	3.669680e-3
GO:0046148	pigment biosynthetic process	3.732013e-3
GO:0048536	spleen development	3.781748e-3
GO:0033962	cytoplasmic mRNA processing body assembly	3.841961e-3
GO:0033169	histone H3-K9 demethylation	3.841961e-3
GO:0072040	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis	3.861518e-3
GO:0060555	induction of necroptosis by extracellular signals	3.928184e-3
GO:0070295	renal water absorption	3.928184e-3
GO:0010466	negative regulation of peptidase activity	3.930813e-3
GO:0007605	sensory perception of sound	3.932378e-3
GO:0010745	negative regulation of macrophage derived foam cell differentiation	3.943087e-3
GO:0043046	DNA methylation involved in gamete generation	3.972016e-3
GO:0045994	positive regulation of translational initiation by iron	4.136112e-3
GO:0002037	negative regulation of L-glutamate transport	4.136112e-3
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	4.157484e-3
GO:0005997	xylulose metabolic process	4.157484e-3
GO:0048170	positive regulation of long-term neuronal synaptic plasticity	4.157484e-3
GO:0010874	regulation of cholesterol efflux	4.193920e-3
GO:0007229	integrin-mediated signaling pathway	4.241697e-3
GO:0031032	actomyosin structure organization	4.243998e-3
GO:0000060	protein import into nucleus, translocation	4.332130e-3
GO:0007094	mitotic cell cycle spindle assembly checkpoint	4.385902e-3
GO:0042221	response to chemical stimulus	4.415601e-3
GO:0090394	negative regulation of excitatory postsynaptic membrane potential	4.457683e-3
GO:0071840	cellular component organization or biogenesis	4.577874e-3
GO:0032369	negative regulation of lipid transport	4.609266e-3
GO:0051954	positive regulation of amine transport	4.616054e-3
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	4.660636e-3
GO:0060765	regulation of androgen receptor signaling pathway	4.729618e-3
GO:0071173	spindle assembly checkpoint	4.745356e-3
GO:0034504	protein localization to nucleus	4.780743e-3
GO:0006572	tyrosine catabolic process	4.804178e-3
GO:0071174	mitotic cell cycle spindle checkpoint	4.819970e-3
GO:0000492	box C/D snoRNP assembly	4.868476e-3
GO:0072017	distal tubule development	4.871703e-3
GO:0006417	regulation of translation	4.880206e-3
GO:0032925	regulation of activin receptor signaling pathway	4.884746e-3
GO:0045669	positive regulation of osteoblast differentiation	5.028973e-3
GO:0072080	nephron tubule development	5.063963e-3
GO:0034375	high-density lipoprotein particle remodeling	5.165417e-3
GO:0050954	sensory perception of mechanical stimulus	5.169934e-3
GO:0032508	DNA duplex unwinding	5.208682e-3
GO:0055114	oxidation-reduction process	5.230622e-3
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	5.249723e-3
GO:0071363	cellular response to growth factor stimulus	5.258179e-3
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	5.368639e-3
GO:0007015	actin filament organization	5.419557e-3
GO:0031577	spindle checkpoint	5.450884e-3
GO:0009581	detection of external stimulus	5.540514e-3
GO:0043412	macromolecule modification	5.543455e-3
GO:0052547	regulation of peptidase activity	5.620098e-3
GO:0002548	monocyte chemotaxis	5.626943e-3
GO:0010740	positive regulation of intracellular protein kinase cascade	5.655688e-3
GO:0032400	melanosome localization	5.723253e-3
GO:2000611	positive regulation of thyroid hormone generation	5.749678e-3
GO:0070988	demethylation	5.750969e-3
GO:0090084	negative regulation of inclusion body assembly	5.802493e-3
GO:0001661	conditioned taste aversion	5.948485e-3
GO:0016577	histone demethylation	6.054778e-3
GO:0051583	dopamine uptake	6.064804e-3
GO:0071316	cellular response to nicotine	6.072014e-3
GO:0060693	regulation of branching involved in salivary gland morphogenesis	6.082814e-3
GO:0009649	entrainment of circadian clock	6.082814e-3
GO:0050665	hydrogen peroxide biosynthetic process	6.090908e-3
GO:0051798	positive regulation of hair follicle development	6.090908e-3
GO:0051705	behavioral interaction between organisms	6.096860e-3
GO:0010875	positive regulation of cholesterol efflux	6.099849e-3
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	6.133424e-3
GO:0032854	positive regulation of Rap GTPase activity	6.133424e-3
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	6.192010e-3
GO:0070663	regulation of leukocyte proliferation	6.245907e-3
GO:0043010	camera-type eye development	6.262631e-3
GO:0048771	tissue remodeling	6.274782e-3
GO:0032392	DNA geometric change	6.274896e-3
GO:0009314	response to radiation	6.289276e-3
GO:0001558	regulation of cell growth	6.306872e-3
GO:0061326	renal tubule development	6.318811e-3
GO:0030259	lipid glycosylation	6.360511e-3
GO:0043266	regulation of potassium ion transport	6.418783e-3
GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein	6.427505e-3
GO:0002019	regulation of renal output by angiotensin	6.499041e-3
GO:0006811	ion transport	6.552362e-3
GO:0032926	negative regulation of activin receptor signaling pathway	6.573847e-3
GO:0031323	regulation of cellular metabolic process	6.591761e-3
GO:0006447	regulation of translational initiation by iron	6.635731e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0030488	tRNA methylation	1.542430e-90
GO:0006400	tRNA modification	3.580398e-68
GO:0001510	RNA methylation	4.011390e-60
GO:0009451	RNA modification	6.272802e-54
GO:0008033	tRNA processing	2.977294e-36
GO:0043414	macromolecule methylation	1.694760e-33
GO:0006399	tRNA metabolic process	1.122106e-29
GO:0032259	methylation	1.236355e-24
GO:0006730	one-carbon metabolic process	2.145465e-24
GO:0034470	ncRNA processing	3.475550e-22
GO:0034660	ncRNA metabolic process	2.575379e-18
GO:0014816	satellite cell differentiation	5.749989e-16
GO:0055114	oxidation-reduction process	6.624137e-14
GO:0043497	regulation of protein heterodimerization activity	1.668236e-11
GO:0060059	embryonic retina morphogenesis in camera-type eye	3.627202e-11
GO:0006694	steroid biosynthetic process	1.491774e-10
GO:0010172	embryonic body morphogenesis	1.641945e-10
GO:0046600	negative regulation of centriole replication	1.823049e-10
GO:0033617	mitochondrial respiratory chain complex IV assembly	3.292778e-10
GO:0001522	pseudouridine synthesis	2.129775e-9
GO:0000768	syncytium formation by plasma membrane fusion	2.470057e-9
GO:0045338	farnesyl diphosphate metabolic process	5.357443e-9
GO:0006974	response to DNA damage stimulus	6.653976e-9
GO:0006949	syncytium formation	1.746637e-8
GO:0051932	synaptic transmission, GABAergic	2.597959e-8
GO:0018963	phthalate metabolic process	4.183068e-8
GO:0021543	pallium development	5.498115e-8
GO:0045663	positive regulation of myoblast differentiation	6.163955e-8
GO:0046599	regulation of centriole replication	6.525927e-8
GO:2000177	regulation of neural precursor cell proliferation	6.651744e-8
GO:0018879	biphenyl metabolic process	8.848695e-8
GO:0007520	myoblast fusion	1.041619e-7
GO:0006396	RNA processing	1.159255e-7
GO:0018894	dibenzo-p-dioxin metabolic process	1.575132e-7
GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching	1.922036e-7
GO:0034551	mitochondrial respiratory chain complex III assembly	3.893258e-7
GO:0010845	positive regulation of reciprocal meiotic recombination	3.893258e-7
GO:2000179	positive regulation of neural precursor cell proliferation	5.089565e-7
GO:0034698	response to gonadotropin stimulus	8.002940e-7
GO:0016090	prenol metabolic process	8.337946e-7
GO:2000691	negative regulation of cardiac muscle cell myoblast differentiation	8.893995e-7
GO:0010659	cardiac muscle cell apoptosis	8.893995e-7
GO:0060042	retina morphogenesis in camera-type eye	1.316335e-6
GO:0090231	regulation of spindle checkpoint	1.392367e-6
GO:0051567	histone H3-K9 methylation	2.512717e-6
GO:0050935	iridophore differentiation	2.848353e-6
GO:0048937	lateral line nerve glial cell development	2.848353e-6
GO:0048643	positive regulation of skeletal muscle tissue development	3.087240e-6
GO:0033128	negative regulation of histone phosphorylation	3.301242e-6
GO:0030263	apoptotic chromosome condensation	5.656390e-6
GO:0035914	skeletal muscle cell differentiation	6.477847e-6
GO:0016126	sterol biosynthetic process	6.799683e-6
GO:0070327	thyroid hormone transport	1.012242e-5
GO:0010824	regulation of centrosome duplication	1.133587e-5
GO:0043951	negative regulation of cAMP-mediated signaling	1.144650e-5
GO:0010976	positive regulation of neuron projection development	1.221651e-5
GO:0070293	renal absorption	1.411767e-5
GO:0032354	response to follicle-stimulating hormone stimulus	1.475478e-5
GO:0016577	histone demethylation	1.986003e-5
GO:0009115	xanthine catabolic process	2.106382e-5
GO:0048880	sensory system development	2.223991e-5
GO:0034968	histone lysine methylation	2.377265e-5
GO:0001757	somite specification	2.537407e-5
GO:0006482	protein demethylation	2.994792e-5
GO:0045665	negative regulation of neuron differentiation	3.085304e-5
GO:0045661	regulation of myoblast differentiation	3.110931e-5
GO:0033554	cellular response to stress	4.056377e-5
GO:0045844	positive regulation of striated muscle tissue development	4.434407e-5
GO:0045666	positive regulation of neuron differentiation	4.555881e-5
GO:0044281	small molecule metabolic process	4.800599e-5
GO:0006479	protein methylation	5.053202e-5
GO:0014902	myotube differentiation	5.169133e-5
GO:0017004	cytochrome complex assembly	5.813314e-5
GO:0046605	regulation of centrosome cycle	5.856244e-5
GO:0032094	response to food	5.906984e-5
GO:0046110	xanthine metabolic process	7.786025e-5
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	8.169865e-5
GO:0043412	macromolecule modification	8.491416e-5
GO:0033127	regulation of histone phosphorylation	8.947279e-5
GO:0010520	regulation of reciprocal meiotic recombination	1.023714e-4
GO:0006702	androgen biosynthetic process	1.052539e-4
GO:0008202	steroid metabolic process	1.124485e-4
GO:0051057	positive regulation of small GTPase mediated signal transduction	1.387195e-4
GO:0006344	maintenance of chromatin silencing	1.497415e-4
GO:0071951	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	1.613980e-4
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	1.624892e-4
GO:0000132	establishment of mitotic spindle orientation	1.725884e-4
GO:0007405	neuroblast proliferation	1.797533e-4
GO:0070534	protein K63-linked ubiquitination	1.873272e-4
GO:0060631	regulation of meiosis I	1.895641e-4
GO:0006145	purine base catabolic process	1.895641e-4
GO:0070076	histone lysine demethylation	1.901286e-4
GO:0031424	keratinization	1.965656e-4
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.978149e-4
GO:0060575	intestinal epithelial cell differentiation	2.091262e-4
GO:0070295	renal water absorption	2.122686e-4
GO:0048846	axon extension involved in axon guidance	2.149482e-4
GO:0040001	establishment of mitotic spindle localization	2.192005e-4
GO:0035674	tricarboxylic acid transmembrane transport	2.299279e-4
GO:0009597	detection of virus	2.299279e-4
GO:0050954	sensory perception of mechanical stimulus	2.617794e-4
GO:0006833	water transport	2.624658e-4
GO:0006720	isoprenoid metabolic process	2.637332e-4
GO:0010900	negative regulation of phosphatidylcholine catabolic process	2.638276e-4
GO:0000185	activation of MAPKKK activity	2.638276e-4
GO:0021766	hippocampus development	2.751812e-4
GO:0051026	chiasma assembly	2.929162e-4
GO:0007605	sensory perception of sound	3.042052e-4
GO:0008209	androgen metabolic process	3.231654e-4
GO:0042445	hormone metabolic process	3.466633e-4
GO:0003097	renal water transport	3.583172e-4
GO:0033108	mitochondrial respiratory chain complex assembly	3.846178e-4
GO:0050891	multicellular organismal water homeostasis	4.076127e-4
GO:0006706	steroid catabolic process	4.255825e-4
GO:0031442	positive regulation of mRNA 3'-end processing	4.586760e-4
GO:0016575	histone deacetylation	4.687639e-4
GO:0045104	intermediate filament cytoskeleton organization	4.741982e-4
GO:0007288	sperm axoneme assembly	4.763726e-4
GO:0021987	cerebral cortex development	5.321854e-4
GO:0042044	fluid transport	5.486374e-4
GO:0045103	intermediate filament-based process	5.949440e-4
GO:0006987	activation of signaling protein activity involved in unfolded protein response	6.217627e-4
GO:0009296	flagellum assembly	6.420697e-4
GO:0015074	DNA integration	6.679426e-4
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	6.714269e-4
GO:0001578	microtubule bundle formation	6.765070e-4
GO:0051293	establishment of spindle localization	6.876368e-4
GO:0006637	acyl-CoA metabolic process	6.876368e-4
GO:0016571	histone methylation	6.933365e-4
GO:0021537	telencephalon development	7.525596e-4
GO:0007600	sensory perception	7.646715e-4
GO:0007519	skeletal muscle tissue development	8.200841e-4
GO:0015746	citrate transport	8.313564e-4
GO:0070988	demethylation	8.435077e-4
GO:0002088	lens development in camera-type eye	8.549976e-4
GO:0051602	response to electrical stimulus	8.667447e-4
GO:0061014	positive regulation of mRNA catabolic process	8.777021e-4
GO:0031440	regulation of mRNA 3'-end processing	8.777021e-4
GO:0043393	regulation of protein binding	9.270400e-4
GO:0050767	regulation of neurogenesis	9.320467e-4
GO:0071371	cellular response to gonadotropin stimulus	9.603089e-4
GO:0048821	erythrocyte development	9.823563e-4
GO:0043064	flagellum organization	9.886441e-4
GO:0033239	negative regulation of cellular amine metabolic process	1.008197e-3
GO:0009581	detection of external stimulus	1.011005e-3
GO:0050756	fractalkine metabolic process	1.013550e-3
GO:0033595	response to genistein	1.013550e-3
GO:0006701	progesterone biosynthetic process	1.013550e-3
GO:0016070	RNA metabolic process	1.015403e-3
GO:0007224	smoothened signaling pathway	1.027264e-3
GO:0072337	modified amino acid transport	1.095854e-3
GO:0060600	dichotomous subdivision of an epithelial terminal unit	1.134126e-3
GO:0030104	water homeostasis	1.134126e-3
GO:0035088	establishment or maintenance of apical/basal cell polarity	1.146078e-3
GO:0071422	succinate transmembrane transport	1.219130e-3
GO:0015991	ATP hydrolysis coupled proton transport	1.228064e-3
GO:0045198	establishment of epithelial cell apical/basal polarity	1.359453e-3
GO:0051297	centrosome organization	1.376433e-3
GO:0070670	response to interleukin-4	1.378253e-3
GO:0060538	skeletal muscle organ development	1.432361e-3
GO:0060696	regulation of phospholipid catabolic process	1.447381e-3
GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration	1.449165e-3
GO:0008535	respiratory chain complex IV assembly	1.549804e-3
GO:0071799	cellular response to prostaglandin D stimulus	1.573401e-3
GO:0048286	lung alveolus development	1.588457e-3
GO:0071557	histone H3-K27 demethylation	1.704671e-3
GO:0035574	histone H4-K20 demethylation	1.704671e-3
GO:0034447	very-low-density lipoprotein particle clearance	1.770488e-3
GO:0032075	positive regulation of nuclease activity	1.809781e-3
GO:0008210	estrogen metabolic process	1.921411e-3
GO:0008299	isoprenoid biosynthetic process	1.943623e-3
GO:0006950	response to stress	2.131449e-3
GO:0045664	regulation of neuron differentiation	2.184304e-3
GO:0021761	limbic system development	2.225657e-3
GO:0042107	cytokine metabolic process	2.287352e-3
GO:0006301	postreplication repair	2.287352e-3
GO:0071372	cellular response to follicle-stimulating hormone stimulus	2.308402e-3
GO:0031023	microtubule organizing center organization	2.396607e-3
GO:0043949	regulation of cAMP-mediated signaling	2.421988e-3
GO:0006703	estrogen biosynthetic process	2.570675e-3
GO:0061370	testosterone biosynthetic process	2.633432e-3
GO:0070869	heterochromatin formation involved in chromatin silencing	2.633432e-3
GO:0035082	axoneme assembly	2.725866e-3
GO:0003091	renal water homeostasis	2.725866e-3
GO:0032350	regulation of hormone metabolic process	2.823806e-3
GO:0001708	cell fate specification	2.886645e-3
GO:0032648	regulation of interferon-beta production	2.887495e-3
GO:0048863	stem cell differentiation	2.907116e-3
GO:0050957	equilibrioception	2.913107e-3
GO:0016125	sterol metabolic process	3.027059e-3
GO:0032981	mitochondrial respiratory chain complex I assembly	3.056407e-3
GO:0009582	detection of abiotic stimulus	3.114938e-3
GO:0072267	metanephric capsule specification	3.248672e-3
GO:0015966	diadenosine tetraphosphate biosynthetic process	3.248672e-3
GO:0048632	negative regulation of skeletal muscle tissue growth	3.248672e-3
GO:0090030	regulation of steroid hormone biosynthetic process	3.314887e-3
GO:0051960	regulation of nervous system development	3.378378e-3
GO:0051905	establishment of pigment granule localization	3.605030e-3
GO:0030011	maintenance of cell polarity	3.802631e-3
GO:0008610	lipid biosynthetic process	3.808394e-3
GO:0072321	chaperone-mediated protein transport	3.823299e-3
GO:0001845	phagolysosome assembly	3.823299e-3
GO:0016202	regulation of striated muscle tissue development	3.958083e-3
GO:0010894	negative regulation of steroid biosynthetic process	4.004967e-3
GO:0031331	positive regulation of cellular catabolic process	4.077733e-3
GO:0010817	regulation of hormone levels	4.112000e-3
GO:0009896	positive regulation of catabolic process	4.148529e-3
GO:0034197	triglyceride transport	4.295108e-3
GO:0007597	blood coagulation, intrinsic pathway	4.295108e-3
GO:0030540	female genitalia development	4.338574e-3
GO:0006629	lipid metabolic process	4.365080e-3
GO:0048634	regulation of muscle organ development	4.466388e-3
GO:0061013	regulation of mRNA catabolic process	4.467801e-3
GO:0090073	positive regulation of protein homodimerization activity	4.670933e-3
GO:0009612	response to mechanical stimulus	4.718774e-3
GO:0006172	ADP biosynthetic process	4.771514e-3
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	4.908277e-3
GO:0018026	peptidyl-lysine monomethylation	4.908277e-3
GO:0044341	sodium-dependent phosphate transport	4.962871e-3
GO:0051890	regulation of cardioblast differentiation	5.079440e-3
GO:0042403	thyroid hormone metabolic process	5.168408e-3
GO:0048484	enteric nervous system development	5.235310e-3
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	5.408389e-3
GO:2000612	regulation of thyroid-stimulating hormone secretion	5.475856e-3
GO:0060045	positive regulation of cardiac muscle cell proliferation	5.487041e-3
GO:0006342	chromatin silencing	5.626101e-3
GO:0060441	epithelial tube branching involved in lung morphogenesis	5.910326e-3
GO:0051918	negative regulation of fibrinolysis	6.095158e-3
GO:0035024	negative regulation of Rho protein signal transduction	6.095158e-3
GO:0045836	positive regulation of meiosis	6.095158e-3
GO:0071305	cellular response to vitamin D	6.325260e-3
GO:0050685	positive regulation of mRNA processing	6.325260e-3
GO:0032479	regulation of type I interferon production	6.357127e-3
GO:0019934	cGMP-mediated signaling	6.357127e-3
GO:0007596	blood coagulation	6.376538e-3
GO:0070936	protein K48-linked ubiquitination	6.438781e-3
GO:0071918	urea transmembrane transport	6.438831e-3
GO:0032727	positive regulation of interferon-alpha production	6.438831e-3
GO:0090304	nucleic acid metabolic process	6.566839e-3
GO:0090031	positive regulation of steroid hormone biosynthetic process	6.677173e-3
GO:0032352	positive regulation of hormone metabolic process	6.733180e-3
GO:0050892	intestinal absorption	6.762556e-3
GO:0034633	retinol transport	6.787338e-3
GO:0030186	melatonin metabolic process	6.787338e-3
GO:0090076	relaxation of skeletal muscle	6.795422e-3
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	6.795422e-3
GO:0060041	retina development in camera-type eye	6.827159e-3
GO:0007599	hemostasis	6.848576e-3
GO:0051056	regulation of small GTPase mediated signal transduction	6.947364e-3
GO:0006476	protein deacetylation	7.005978e-3
GO:0045541	negative regulation of cholesterol biosynthetic process	7.062088e-3
GO:0042448	progesterone metabolic process	7.186161e-3
GO:0002065	columnar/cuboidal epithelial cell differentiation	7.196172e-3
GO:0034754	cellular hormone metabolic process	7.263419e-3
GO:0048641	regulation of skeletal muscle tissue development	7.317684e-3
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	7.638407e-3
GO:0006101	citrate metabolic process	7.638407e-3
GO:0035425	autocrine signaling	7.719876e-3
GO:0060014	granulosa cell differentiation	7.719876e-3
GO:0071236	cellular response to antibiotic	7.840309e-3
GO:0090184	positive regulation of kidney development	7.859844e-3
GO:0035601	protein deacylation	8.029295e-3
GO:0032025	response to cobalt ion	8.084511e-3
GO:0035458	cellular response to interferon-beta	8.108840e-3
GO:0010985	negative regulation of lipoprotein particle clearance	8.108840e-3
GO:0007339	binding of sperm to zona pellucida	8.116095e-3
GO:0046686	response to cadmium ion	8.184480e-3
GO:0035623	renal glucose absorption	8.226045e-3
GO:0042537	benzene-containing compound metabolic process	8.444687e-3
GO:0032069	regulation of nuclease activity	8.547353e-3
GO:0071346	cellular response to interferon-gamma	8.609023e-3
GO:0060395	SMAD protein signal transduction	8.688234e-3
GO:0034382	chylomicron remnant clearance	8.816063e-3
GO:0051005	negative regulation of lipoprotein lipase activity	8.816063e-3
GO:0009415	response to water	8.816063e-3
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	9.051734e-3
GO:0044339	canonical Wnt receptor signaling pathway involved in osteoblast differentiation	9.140694e-3
GO:0022007	convergent extension involved in neural plate elongation	9.140694e-3
GO:0044338	canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation	9.140694e-3
GO:0032008	positive regulation of TOR signaling cascade	9.185152e-3
GO:0001539	ciliary or flagellar motility	9.185152e-3
GO:0035089	establishment of apical/basal cell polarity	9.524210e-3
GO:0051149	positive regulation of muscle cell differentiation	9.601491e-3
GO:0060420	regulation of heart growth	9.713784e-3
GO:0006426	glycyl-tRNA aminoacylation	9.788536e-3
GO:0006695	cholesterol biosynthetic process	9.854590e-3
GO:0050702	interleukin-1 beta secretion	9.904463e-3
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	1.003869e-2
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	1.015770e-2
GO:0033238	regulation of cellular amine metabolic process	1.015770e-2
GO:0006929	substrate-dependent cell migration	1.015770e-2
GO:0031122	cytoplasmic microtubule organization	1.024486e-2
GO:0030859	polarized epithelial cell differentiation	1.057083e-2
GO:0051917	regulation of fibrinolysis	1.057837e-2
GO:0045039	protein import into mitochondrial inner membrane	1.070424e-2
GO:0032611	interleukin-1 beta production	1.070424e-2
GO:0021542	dentate gyrus development	1.072838e-2
GO:0002042	cell migration involved in sprouting angiogenesis	1.076793e-2
GO:0035036	sperm-egg recognition	1.091950e-2
GO:0043434	response to peptide hormone stimulus	1.104525e-2
GO:0018904	organic ether metabolic process	1.117227e-2
GO:0051875	pigment granule localization	1.119091e-2
GO:2000178	negative regulation of neural precursor cell proliferation	1.125664e-2
GO:2000142	regulation of transcription initiation, DNA-dependent	1.132198e-2
GO:0042780	tRNA 3'-end processing	1.147144e-2
GO:0034553	mitochondrial respiratory chain complex II assembly	1.147144e-2
GO:0071276	cellular response to cadmium ion	1.154033e-2
GO:0048668	collateral sprouting	1.154033e-2
GO:0010984	regulation of lipoprotein particle clearance	1.162506e-2
GO:0048593	camera-type eye morphogenesis	1.197326e-2
GO:0001839	neural plate morphogenesis	1.227536e-2
GO:0035372	protein localization to microtubule	1.241297e-2
GO:0010724	regulation of definitive erythrocyte differentiation	1.241297e-2
GO:0048742	regulation of skeletal muscle fiber development	1.251700e-2
GO:0015698	inorganic anion transport	1.264106e-2
GO:0007163	establishment or maintenance of cell polarity	1.270621e-2
GO:0043648	dicarboxylic acid metabolic process	1.302780e-2
GO:0046580	negative regulation of Ras protein signal transduction	1.308523e-2
GO:0046113	nucleobase catabolic process	1.313114e-2
GO:0060536	cartilage morphogenesis	1.324518e-2
GO:0009611	response to wounding	1.330147e-2
GO:0010171	body morphogenesis	1.332639e-2
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	1.350382e-2
GO:0045668	negative regulation of osteoblast differentiation	1.355288e-2
GO:0030324	lung development	1.368895e-2
GO:0007422	peripheral nervous system development	1.394739e-2
GO:0060347	heart trabecula formation	1.396793e-2
GO:0045989	positive regulation of striated muscle contraction	1.396793e-2
GO:0035414	negative regulation of catenin import into nucleus	1.396793e-2
GO:0018022	peptidyl-lysine methylation	1.396793e-2
GO:0048675	axon extension	1.405608e-2
GO:0042446	hormone biosynthetic process	1.449716e-2
GO:0030901	midbrain development	1.460413e-2
GO:0071375	cellular response to peptide hormone stimulus	1.504294e-2
GO:0030038	contractile actin filament bundle assembly	1.518530e-2
GO:0035912	dorsal aorta morphogenesis	1.518530e-2
GO:0046785	microtubule polymerization	1.525246e-2
GO:0002230	positive regulation of defense response to virus by host	1.525246e-2
GO:0030323	respiratory tube development	1.537351e-2
GO:0043149	stress fiber assembly	1.563847e-2
GO:0051058	negative regulation of small GTPase mediated signal transduction	1.568734e-2
GO:0050974	detection of mechanical stimulus involved in sensory perception	1.581575e-2
GO:0000413	protein peptidyl-prolyl isomerization	1.596722e-2
GO:0009583	detection of light stimulus	1.646501e-2
GO:0030010	establishment of cell polarity	1.672478e-2
GO:0035519	protein K29-linked ubiquitination	1.720983e-2
GO:0015959	diadenosine polyphosphate metabolic process	1.720983e-2
GO:0008057	eye pigment granule organization	1.720983e-2
GO:0005997	xylulose metabolic process	1.720983e-2
GO:0006820	anion transport	1.725609e-2
GO:0032647	regulation of interferon-alpha production	1.733177e-2
GO:0002344	B cell affinity maturation	1.733177e-2
GO:0010467	gene expression	1.754132e-2
GO:0008090	retrograde axon cargo transport	1.764720e-2
GO:0030318	melanocyte differentiation	1.773182e-2
GO:0033522	histone H2A ubiquitination	1.796630e-2
GO:0050810	regulation of steroid biosynthetic process	1.818191e-2
GO:0048259	regulation of receptor-mediated endocytosis	1.865527e-2
GO:0006071	glycerol metabolic process	1.905903e-2
GO:0034097	response to cytokine stimulus	1.909744e-2
GO:0010164	response to cesium ion	1.934193e-2
GO:0015734	taurine transport	1.934193e-2
GO:0006481	C-terminal protein methylation	1.934193e-2
GO:0046885	regulation of hormone biosynthetic process	1.937029e-2
GO:0050701	interleukin-1 secretion	1.956124e-2
GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process	1.956124e-2
GO:0070193	synaptonemal complex organization	1.956138e-2
GO:0050931	pigment cell differentiation	1.981150e-2
GO:0043496	regulation of protein homodimerization activity	2.052092e-2
GO:0032612	interleukin-1 production	2.073246e-2
GO:0045652	regulation of megakaryocyte differentiation	2.105984e-2
GO:0046886	positive regulation of hormone biosynthetic process	2.129234e-2
GO:0021837	motogenic signaling involved in postnatal olfactory bulb interneuron migration	2.157852e-2
GO:0043312	neutrophil degranulation	2.157852e-2
GO:0070544	histone H3-K36 demethylation	2.164331e-2
GO:0051561	elevation of mitochondrial calcium ion concentration	2.164331e-2
GO:0035690	cellular response to drug	2.167464e-2
GO:0050688	regulation of defense response to virus	2.279710e-2
GO:0002446	neutrophil mediated immunity	2.283858e-2
GO:0050982	detection of mechanical stimulus	2.285105e-2
GO:0045814	negative regulation of gene expression, epigenetic	2.285105e-2
GO:0051186	cofactor metabolic process	2.382119e-2
GO:0048631	regulation of skeletal muscle tissue growth	2.391662e-2
GO:0048592	eye morphogenesis	2.436521e-2
GO:0030828	positive regulation of cGMP biosynthetic process	2.447233e-2
GO:0015840	urea transport	2.447233e-2
GO:0040020	regulation of meiosis	2.484362e-2
GO:0006084	acetyl-CoA metabolic process	2.500493e-2
GO:0070509	calcium ion import	2.520724e-2
GO:2000340	positive regulation of chemokine (C-X-C motif) ligand 1 production	2.525561e-2
GO:0032658	regulation of interleukin-15 production	2.525561e-2
GO:0030195	negative regulation of blood coagulation	2.571826e-2
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	2.579432e-2
GO:0051488	activation of anaphase-promoting complex activity	2.579432e-2
GO:0034770	histone H4-K20 methylation	2.579432e-2
GO:0002011	morphogenesis of an epithelial sheet	2.591259e-2
GO:0043526	neuroprotection	2.620996e-2
GO:0070059	apoptosis in response to endoplasmic reticulum stress	2.634488e-2
GO:0072076	nephrogenic mesenchyme development	2.635329e-2
GO:0060043	regulation of cardiac muscle cell proliferation	2.685558e-2
GO:0019400	alditol metabolic process	2.701252e-2
GO:0031057	negative regulation of histone modification	2.757421e-2
GO:0050684	regulation of mRNA processing	2.785012e-2
GO:0050878	regulation of body fluid levels	2.875518e-2
GO:0034766	negative regulation of ion transmembrane transport	2.888564e-2
GO:0071464	cellular response to hydrostatic pressure	2.888564e-2
GO:0034141	positive regulation of toll-like receptor 3 signaling pathway	2.888564e-2
GO:0007379	segment specification	2.958972e-2
GO:0048515	spermatid differentiation	2.972889e-2
GO:0030513	positive regulation of BMP signaling pathway	3.001853e-2
GO:0051445	regulation of meiotic cell cycle	3.050151e-2
GO:0001840	neural plate development	3.117884e-2
GO:0010893	positive regulation of steroid biosynthetic process	3.137755e-2
GO:0007099	centriole replication	3.145757e-2
GO:0042113	B cell activation	3.168291e-2
GO:0060192	negative regulation of lipase activity	3.209098e-2
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	3.295313e-2
GO:0035567	non-canonical Wnt receptor signaling pathway	3.298842e-2
GO:0000183	chromatin silencing at rDNA	3.333835e-2
GO:0060828	regulation of canonical Wnt receptor signaling pathway	3.360571e-2
GO:0046618	drug export	3.422619e-2
GO:0010735	positive regulation of transcription via serum response element binding	3.422619e-2
GO:0042886	amide transport	3.451294e-2
GO:0042472	inner ear morphogenesis	3.471171e-2
GO:0042742	defense response to bacterium	3.555577e-2
GO:0032728	positive regulation of interferon-beta production	3.558296e-2
GO:0007521	muscle cell fate determination	3.558296e-2
GO:0048261	negative regulation of receptor-mediated endocytosis	3.562552e-2
GO:0045717	negative regulation of fatty acid biosynthetic process	3.654511e-2
GO:0032092	positive regulation of protein binding	3.759855e-2
GO:0042666	negative regulation of ectodermal cell fate specification	3.764337e-2
GO:0060965	negative regulation of gene silencing by miRNA	3.764337e-2
GO:0070933	histone H4 deacetylation	3.771597e-2
GO:0060437	lung growth	3.771597e-2
GO:0060535	trachea cartilage morphogenesis	3.771597e-2
GO:0055021	regulation of cardiac muscle tissue growth	3.815466e-2
GO:0045732	positive regulation of protein catabolic process	3.824482e-2
GO:0000226	microtubule cytoskeleton organization	3.856333e-2
GO:0051865	protein autoubiquitination	3.857483e-2
GO:0006817	phosphate ion transport	3.910985e-2
GO:0050973	detection of mechanical stimulus involved in equilibrioception	3.937243e-2
GO:0045653	negative regulation of megakaryocyte differentiation	3.937243e-2
GO:0050691	regulation of defense response to virus by host	3.939082e-2
GO:0060026	convergent extension	3.939082e-2
GO:0030220	platelet formation	3.939082e-2
GO:0015672	monovalent inorganic cation transport	3.985897e-2
GO:0033561	regulation of water loss via skin	3.991634e-2
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	4.106525e-2
GO:0060117	auditory receptor cell development	4.136077e-2
GO:0031346	positive regulation of cell projection organization	4.137074e-2
GO:0090090	negative regulation of canonical Wnt receptor signaling pathway	4.169636e-2
GO:0060284	regulation of cell development	4.186686e-2
GO:0051657	maintenance of organelle location	4.236767e-2
GO:0033169	histone H3-K9 demethylation	4.279423e-2
GO:0021827	postnatal olfactory bulb interneuron migration	4.279423e-2
GO:0055062	phosphate ion homeostasis	4.282902e-2
GO:0007199	G-protein signaling, coupled to cGMP nucleotide second messenger	4.282902e-2
GO:2000594	positive regulation of metanephric DCT cell differentiation	4.288591e-2
GO:0039003	pronephric field specification	4.288591e-2
GO:0072305	negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis	4.288591e-2
GO:0006099	tricarboxylic acid cycle	4.362668e-2
GO:0014819	regulation of skeletal muscle contraction	4.411146e-2
GO:0048240	sperm capacitation	4.442546e-2
GO:0032375	negative regulation of cholesterol transport	4.442546e-2
GO:0006139	nucleobase-containing compound metabolic process	4.447376e-2
GO:0046519	sphingoid metabolic process	4.448684e-2
GO:0034392	negative regulation of smooth muscle cell apoptosis	4.455913e-2
GO:0021847	ventricular zone neuroblast division	4.455913e-2
GO:0019751	polyol metabolic process	4.486651e-2
GO:0045933	positive regulation of muscle contraction	4.505073e-2
GO:0007286	spermatid development	4.581561e-2
GO:0016101	diterpenoid metabolic process	4.583754e-2
GO:0042732	D-xylose metabolic process	4.593507e-2
GO:0072003	kidney rudiment formation	4.593507e-2
GO:0044111	development involved in symbiotic interaction	4.593507e-2
GO:0006398	histone mRNA 3'-end processing	4.593507e-2
GO:0010768	negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	4.593507e-2
GO:0019089	transmission of virus	4.593507e-2
GO:0018208	peptidyl-proline modification	4.616588e-2
GO:0007602	phototransduction	4.630052e-2
GO:0051656	establishment of organelle localization	4.642436e-2
GO:0061384	heart trabecular morphogenesis	4.654205e-2
GO:0030431	sleep	4.654205e-2
GO:0045940	positive regulation of steroid metabolic process	4.694009e-2
GO:0021869	forebrain ventricular zone progenitor cell division	4.808676e-2
GO:0051904	pigment granule transport	4.819575e-2
GO:0002339	B cell selection	4.819575e-2
GO:0009414	response to water deprivation	4.819575e-2
GO:0040018	positive regulation of multicellular organism growth	4.826516e-2
GO:0007214	gamma-aminobutyric acid signaling pathway	4.871755e-2
GO:0043410	positive regulation of MAPKKK cascade	4.904978e-2
GO:0031639	plasminogen activation	4.906130e-2
GO:0006603	phosphocreatine metabolic process	4.906130e-2
GO:0050819	negative regulation of coagulation	4.907386e-2
GO:0060541	respiratory system development	4.914060e-2
GO:0050877	neurological system process	4.969269e-2
GO:0007129	synapsis	4.982742e-2
GO:0060125	negative regulation of growth hormone secretion	4.987380e-2
GO:0051463	negative regulation of cortisol secretion	4.987380e-2
GO:0045769	negative regulation of asymmetric cell division	4.987380e-2