Novel motif:17

name:	motif17_CGCTAN

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0000398	nuclear mRNA splicing, via spliceosome	1.060318e-12
GO:0000375	RNA splicing, via transesterification reactions	4.407971e-12
GO:0006361	transcription initiation from RNA polymerase I promoter	6.056491e-11
GO:0008272	sulfate transport	6.297564e-11
GO:0006353	transcription termination, DNA-dependent	3.444811e-10
GO:0006289	nucleotide-excision repair	7.149853e-10
GO:0000413	protein peptidyl-prolyl isomerization	2.069235e-9
GO:0006283	transcription-coupled nucleotide-excision repair	2.307028e-9
GO:0006354	transcription elongation, DNA-dependent	5.781753e-9
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	1.460469e-8
GO:0009589	detection of UV	1.460469e-8
GO:0032425	positive regulation of mismatch repair	1.911162e-8
GO:0006368	transcription elongation from RNA polymerase II promoter	2.047792e-8
GO:0006396	RNA processing	2.646895e-8
GO:0070127	tRNA aminoacylation for mitochondrial protein translation	2.879320e-8
GO:0070145	mitochondrial asparaginyl-tRNA aminoacylation	4.423798e-8
GO:0006360	transcription from RNA polymerase I promoter	5.421558e-8
GO:0050434	positive regulation of viral transcription	8.594656e-8
GO:0071423	malate transmembrane transport	1.068597e-7
GO:0015709	thiosulfate transport	1.068597e-7
GO:0006363	termination of RNA polymerase I transcription	1.492514e-7
GO:0018192	enzyme active site formation via L-cysteine persulfide	1.888980e-7
GO:0018208	peptidyl-proline modification	4.194932e-7
GO:0032543	mitochondrial translation	5.760991e-7
GO:0000959	mitochondrial RNA metabolic process	8.748660e-7
GO:0000718	nucleotide-excision repair, DNA damage removal	9.253979e-7
GO:0006362	transcription elongation from RNA polymerase I promoter	1.086523e-6
GO:0032423	regulation of mismatch repair	1.170444e-6
GO:0016071	mRNA metabolic process	1.269504e-6
GO:0008380	RNA splicing	2.278977e-6
GO:0046782	regulation of viral transcription	2.350287e-6
GO:0006370	mRNA capping	3.732743e-6
GO:0018364	peptidyl-glutamine methylation	4.625236e-6
GO:0006397	mRNA processing	6.007310e-6
GO:0035883	enteroendocrine cell differentiation	6.357998e-6
GO:0048339	paraxial mesoderm development	9.386368e-6
GO:0021591	ventricular system development	9.824088e-6
GO:0015761	mannose transport	1.402059e-5
GO:0009452	RNA capping	1.402071e-5
GO:0021670	lateral ventricle development	1.569917e-5
GO:0031627	telomeric loop formation	1.628915e-5
GO:0006399	tRNA metabolic process	1.870218e-5
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	1.888018e-5
GO:0016032	viral reproduction	2.005638e-5
GO:0043441	acetoacetic acid biosynthetic process	2.508275e-5
GO:0016926	protein desumoylation	2.555038e-5
GO:0030206	chondroitin sulfate biosynthetic process	2.558339e-5
GO:0048341	paraxial mesoderm formation	2.777398e-5
GO:0035545	determination of left/right asymmetry in nervous system	3.043464e-5
GO:0032790	ribosome disassembly	3.235545e-5
GO:0018023	peptidyl-lysine trimethylation	3.238524e-5
GO:0072329	monocarboxylic acid catabolic process	4.094247e-5
GO:0043039	tRNA aminoacylation	4.202282e-5
GO:0000216	M/G1 transition of mitotic cell cycle	4.286811e-5
GO:0006405	RNA export from nucleus	4.766133e-5
GO:0042506	tyrosine phosphorylation of Stat5 protein	5.261235e-5
GO:0046501	protoporphyrinogen IX metabolic process	5.879114e-5
GO:0046358	butyrate biosynthetic process	7.780695e-5
GO:0006261	DNA-dependent DNA replication	8.198097e-5
GO:0007635	chemosensory behavior	8.695021e-5
GO:0061157	mRNA destabilization	8.856015e-5
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	8.856015e-5
GO:0006421	asparaginyl-tRNA aminoacylation	9.559730e-5
GO:0006406	mRNA export from nucleus	1.053516e-4
GO:0043461	proton-transporting ATP synthase complex assembly	1.068774e-4
GO:0019348	dolichol metabolic process	1.068774e-4
GO:0046086	adenosine biosynthetic process	1.088657e-4
GO:0048291	isotype switching to IgG isotypes	1.149071e-4
GO:0032900	negative regulation of neurotrophin production	1.149071e-4
GO:0002368	B cell cytokine production	1.149071e-4
GO:0032244	positive regulation of nucleoside transport	1.149071e-4
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	1.149071e-4
GO:0042228	interleukin-8 biosynthetic process	1.168631e-4
GO:0050689	negative regulation of defense response to virus by host	1.314009e-4
GO:0006457	protein folding	1.343476e-4
GO:0042168	heme metabolic process	1.485505e-4
GO:0048524	positive regulation of viral reproduction	1.528125e-4
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	1.551621e-4
GO:0060486	Clara cell differentiation	1.614071e-4
GO:0051320	S phase	1.634049e-4
GO:0006525	arginine metabolic process	1.659828e-4
GO:0009062	fatty acid catabolic process	1.776400e-4
GO:0060087	relaxation of vascular smooth muscle	1.870849e-4
GO:0006646	phosphatidylethanolamine biosynthetic process	1.931631e-4
GO:0042696	menarche	1.945761e-4
GO:0032074	negative regulation of nuclease activity	2.030694e-4
GO:0006352	transcription initiation, DNA-dependent	2.052748e-4
GO:0022616	DNA strand elongation	2.275230e-4
GO:0046395	carboxylic acid catabolic process	2.299918e-4
GO:0050779	RNA destabilization	2.327836e-4
GO:0034660	ncRNA metabolic process	2.354498e-4
GO:0046950	cellular ketone body metabolic process	2.385174e-4
GO:0006423	cysteinyl-tRNA aminoacylation	2.634420e-4
GO:0043248	proteasome assembly	2.933495e-4
GO:0006783	heme biosynthetic process	2.998288e-4
GO:0000084	S phase of mitotic cell cycle	3.004029e-4
GO:0035845	photoreceptor cell outer segment organization	3.325455e-4
GO:0010452	histone H3-K36 methylation	3.384574e-4
GO:0006367	transcription initiation from RNA polymerase II promoter	3.403565e-4
GO:0030208	dermatan sulfate biosynthetic process	3.547421e-4
GO:0021542	dentate gyrus development	3.591491e-4
GO:0006390	transcription from mitochondrial promoter	3.832562e-4
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	3.871403e-4
GO:0006369	termination of RNA polymerase II transcription	3.929832e-4
GO:0019264	glycine biosynthetic process from serine	4.172644e-4
GO:0042538	hyperosmotic salinity response	4.280955e-4
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	4.598455e-4
GO:0051790	short-chain fatty acid biosynthetic process	4.605315e-4
GO:0046416	D-amino acid metabolic process	4.879431e-4
GO:0048340	paraxial mesoderm morphogenesis	4.912757e-4
GO:0006271	DNA strand elongation involved in DNA replication	4.924004e-4
GO:0030826	regulation of cGMP biosynthetic process	4.970184e-4
GO:0046105	thymidine biosynthetic process	5.186993e-4
GO:0016598	protein arginylation	5.186993e-4
GO:0021759	globus pallidus development	5.192250e-4
GO:0000723	telomere maintenance	5.262665e-4
GO:0042503	tyrosine phosphorylation of Stat3 protein	5.563521e-4
GO:0046951	ketone body biosynthetic process	6.019270e-4
GO:0048343	paraxial mesodermal cell fate commitment	6.333968e-4
GO:0032119	sequestering of zinc ion	6.475546e-4
GO:0007263	nitric oxide mediated signal transduction	6.759511e-4
GO:0000244	assembly of spliceosomal tri-snRNP	6.790549e-4
GO:0006418	tRNA aminoacylation for protein translation	6.845323e-4
GO:0003310	pancreatic A cell differentiation	6.936181e-4
GO:0018352	protein-pyridoxal-5-phosphate linkage	7.499614e-4
GO:0006458	'de novo' protein folding	7.594691e-4
GO:0015866	ADP transport	7.767828e-4
GO:0010836	negative regulation of protein ADP-ribosylation	7.808198e-4
GO:0070071	proton-transporting two-sector ATPase complex assembly	7.910874e-4
GO:0060972	left/right pattern formation	7.911010e-4
GO:0010833	telomere maintenance via telomere lengthening	8.654661e-4
GO:0071422	succinate transmembrane transport	8.801373e-4
GO:0010701	positive regulation of norepinephrine secretion	9.422102e-4
GO:0006781	succinyl-CoA pathway	9.559969e-4
GO:0006545	glycine biosynthetic process	1.002172e-3
GO:0032988	ribonucleoprotein complex disassembly	1.004015e-3
GO:0006024	glycosaminoglycan biosynthetic process	1.055419e-3
GO:0046813	virion attachment, binding of host cell surface receptor	1.097719e-3
GO:0006023	aminoglycan biosynthetic process	1.170074e-3
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	1.172550e-3
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	1.172550e-3
GO:0031123	RNA 3'-end processing	1.226393e-3
GO:0072553	terminal button organization	1.255075e-3
GO:0071544	diphosphoinositol polyphosphate catabolic process	1.255075e-3
GO:0070535	histone H2A K63-linked ubiquitination	1.255075e-3
GO:0021873	forebrain neuroblast division	1.261350e-3
GO:0035082	axoneme assembly	1.280846e-3
GO:0030828	positive regulation of cGMP biosynthetic process	1.385127e-3
GO:0045116	protein neddylation	1.402208e-3
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	1.403303e-3
GO:0009070	serine family amino acid biosynthetic process	1.410938e-3
GO:0033108	mitochondrial respiratory chain complex assembly	1.523969e-3
GO:0003420	regulation of growth plate cartilage chondrocyte proliferation	1.561503e-3
GO:0060455	negative regulation of gastric acid secretion	1.561503e-3
GO:0006189	'de novo' IMP biosynthetic process	1.561503e-3
GO:0060929	atrioventricular node cell fate commitment	1.578053e-3
GO:0060928	atrioventricular node cell development	1.578053e-3
GO:0003168	cardiac Purkinje fiber cell differentiation	1.578053e-3
GO:0003342	proepicardium development	1.578053e-3
GO:0043538	regulation of actin phosphorylation	1.640221e-3
GO:0006270	DNA-dependent DNA replication initiation	1.644711e-3
GO:0060670	branching involved in embryonic placenta morphogenesis	1.660755e-3
GO:0003334	keratinocyte development	1.660755e-3
GO:0000173	inactivation of MAPK activity involved in osmosensory signaling pathway	1.683142e-3
GO:0046718	entry of virus into host cell	1.686299e-3
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	1.751672e-3
GO:0070673	response to interleukin-18	1.769062e-3
GO:0010760	negative regulation of macrophage chemotaxis	1.797087e-3
GO:0014739	positive regulation of muscle hyperplasia	1.797087e-3
GO:0006797	polyphosphate metabolic process	1.797087e-3
GO:0045986	negative regulation of smooth muscle contraction	1.853867e-3
GO:0007100	mitotic centrosome separation	1.912578e-3
GO:0021526	medial motor column neuron differentiation	2.006452e-3
GO:0003326	pancreatic A cell fate commitment	2.006452e-3
GO:0003329	pancreatic PP cell fate commitment	2.006452e-3
GO:0032200	telomere organization	2.059015e-3
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	2.111094e-3
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	2.146965e-3
GO:0042558	pteridine-containing compound metabolic process	2.244892e-3
GO:0035329	hippo signaling cascade	2.333158e-3
GO:0090329	regulation of DNA-dependent DNA replication	2.413222e-3
GO:0060510	Type II pneumocyte differentiation	2.453386e-3
GO:0010722	regulation of ferrochelatase activity	2.595492e-3
GO:0006409	tRNA export from nucleus	2.595492e-3
GO:0060487	lung epithelial cell differentiation	2.709959e-3
GO:0032981	mitochondrial respiratory chain complex I assembly	2.779042e-3
GO:0035499	carnosine biosynthetic process	2.790374e-3
GO:0006529	asparagine biosynthetic process	2.790374e-3
GO:0010983	positive regulation of high-density lipoprotein particle clearance	2.790374e-3
GO:0044091	membrane biogenesis	2.812371e-3
GO:0070647	protein modification by small protein conjugation or removal	2.825944e-3
GO:0018342	protein prenylation	2.847507e-3
GO:0007231	osmosensory signaling pathway	2.875875e-3
GO:0032600	chemokine receptor transport out of membrane raft	2.888733e-3
GO:0032913	negative regulation of transforming growth factor beta3 production	2.888733e-3
GO:0032597	B cell receptor transport into membrane raft	2.888733e-3
GO:0090042	tubulin deacetylation	3.040901e-3
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	3.040901e-3
GO:0032581	ER-dependent peroxisome organization	3.040901e-3
GO:0070846	Hsp90 deacetylation	3.040901e-3
GO:0006065	UDP-glucuronate biosynthetic process	3.255420e-3
GO:0072011	glomerular endothelium development	3.277270e-3
GO:0072144	glomerular mesangial cell development	3.277270e-3
GO:0090234	regulation of kinetochore assembly	3.285813e-3
GO:0090169	regulation of spindle assembly	3.285813e-3
GO:0006644	phospholipid metabolic process	3.401884e-3
GO:0006356	regulation of transcription from RNA polymerase I promoter	3.461002e-3
GO:0060669	embryonic placenta morphogenesis	3.623824e-3
GO:0021869	forebrain ventricular zone progenitor cell division	3.664645e-3
GO:0002098	tRNA wobble uridine modification	3.677062e-3
GO:0034227	tRNA thio-modification	3.677062e-3
GO:0021986	habenula development	3.709247e-3
GO:0034970	histone H3-R2 methylation	3.787466e-3
GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway	3.825243e-3
GO:0070682	proteasome regulatory particle assembly	3.926211e-3
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	3.979612e-3
GO:0021658	rhombomere 3 morphogenesis	3.983738e-3
GO:0016070	RNA metabolic process	4.165672e-3
GO:0006563	L-serine metabolic process	4.201490e-3
GO:0006538	glutamate catabolic process	4.212601e-3
GO:0071635	negative regulation of transforming growth factor beta production	4.215634e-3
GO:0006559	L-phenylalanine catabolic process	4.227918e-3
GO:0009225	nucleotide-sugar metabolic process	4.270053e-3
GO:0032765	positive regulation of mast cell cytokine production	4.342690e-3
GO:0051255	spindle midzone assembly	4.385613e-3
GO:0006383	transcription from RNA polymerase III promoter	4.392244e-3
GO:0006635	fatty acid beta-oxidation	4.403867e-3
GO:2000773	negative regulation of cellular senescence	4.467868e-3
GO:0043697	cell dedifferentiation	4.467868e-3
GO:0045627	positive regulation of T-helper 1 cell differentiation	4.559841e-3
GO:0045993	negative regulation of translational initiation by iron	4.765307e-3
GO:0046986	negative regulation of hemoglobin biosynthetic process	4.765307e-3
GO:0014738	regulation of muscle hyperplasia	4.769225e-3
GO:0006900	membrane budding	4.773952e-3
GO:0015961	diadenosine polyphosphate catabolic process	4.877714e-3
GO:0042109	lymphotoxin A biosynthetic process	4.877714e-3
GO:0006527	arginine catabolic process	4.903278e-3
GO:0006386	termination of RNA polymerase III transcription	4.932436e-3
GO:0006385	transcription elongation from RNA polymerase III promoter	4.932436e-3
GO:0006779	porphyrin-containing compound biosynthetic process	4.992119e-3
GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation	5.009829e-3
GO:0000080	G1 phase of mitotic cell cycle	5.029279e-3
GO:0042073	intraflagellar transport	5.040508e-3
GO:0018283	iron incorporation into metallo-sulfur cluster	5.098532e-3
GO:0043268	positive regulation of potassium ion transport	5.134308e-3
GO:0044268	multicellular organismal protein metabolic process	5.141432e-3
GO:0090304	nucleic acid metabolic process	5.156297e-3
GO:0060430	lung saccule development	5.352453e-3
GO:0006478	peptidyl-tyrosine sulfation	5.357769e-3
GO:0031124	mRNA 3'-end processing	5.459160e-3
GO:0006760	folic acid-containing compound metabolic process	5.580201e-3
GO:0006465	signal peptide processing	5.594911e-3
GO:0061084	negative regulation of protein refolding	5.603231e-3
GO:0051935	glutamate uptake involved in synaptic transmission	5.700945e-3
GO:0006540	glutamate decarboxylation to succinate	5.708496e-3
GO:0071951	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	5.739279e-3
GO:0071557	histone H3-K27 demethylation	5.914911e-3
GO:0035574	histone H4-K20 demethylation	5.914911e-3
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	5.952380e-3
GO:0051088	PMA-inducible membrane protein ectodomain proteolysis	5.952380e-3
GO:0050951	sensory perception of temperature stimulus	6.057856e-3
GO:2000124	regulation of endocannabinoid signaling pathway	6.057856e-3
GO:0000076	DNA replication checkpoint	6.057856e-3
GO:0051549	positive regulation of keratinocyte migration	6.066444e-3
GO:0010837	regulation of keratinocyte proliferation	6.100472e-3
GO:0043128	positive regulation of 1-phosphatidylinositol 4-kinase activity	6.151175e-3
GO:0035470	positive regulation of vascular wound healing	6.151175e-3
GO:0060971	embryonic heart tube left/right pattern formation	6.181765e-3
GO:0060920	pacemaker cell differentiation	6.181765e-3
GO:0046474	glycerophospholipid biosynthetic process	6.213402e-3
GO:0006778	porphyrin-containing compound metabolic process	6.269180e-3
GO:0040040	thermosensory behavior	6.465616e-3
GO:0016574	histone ubiquitination	6.596760e-3
GO:0051256	spindle midzone assembly involved in mitosis	6.759011e-3
GO:0032912	negative regulation of transforming growth factor beta2 production	6.759011e-3
GO:0035881	amacrine cell differentiation	6.912200e-3
GO:0035583	negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta	6.912352e-3
GO:0070159	mitochondrial threonyl-tRNA aminoacylation	7.042157e-3
GO:0070543	response to linoleic acid	7.042157e-3
GO:0034696	response to prostaglandin F stimulus	7.042157e-3
GO:0006505	GPI anchor metabolic process	7.106556e-3
GO:0061011	hepatic duct development	7.121945e-3
GO:0051083	'de novo' cotranslational protein folding	7.121945e-3
GO:0006414	translational elongation	7.244459e-3
GO:0031860	telomeric 3' overhang formation	7.301090e-3
GO:0018931	naphthalene metabolic process	7.301090e-3
GO:0007113	endomitotic cell cycle	7.301090e-3
GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation	7.301090e-3
GO:0060708	spongiotrophoblast differentiation	7.396484e-3
GO:0030260	entry into host cell	7.438282e-3
GO:0001696	gastric acid secretion	7.607346e-3
GO:0070534	protein K63-linked ubiquitination	7.679024e-3
GO:0070103	regulation of interleukin-6-mediated signaling pathway	7.708123e-3
GO:0042226	interleukin-6 biosynthetic process	7.721852e-3
GO:0071826	ribonucleoprotein complex subunit organization	7.867984e-3
GO:0022601	menstrual cycle phase	7.940599e-3
GO:0071224	cellular response to peptidoglycan	7.986097e-3
GO:0033687	osteoblast proliferation	8.490387e-3
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	8.559415e-3
GO:0051084	'de novo' posttranslational protein folding	8.839915e-3
GO:0070105	positive regulation of interleukin-6-mediated signaling pathway	8.905010e-3
GO:0031284	positive regulation of guanylate cyclase activity	8.905010e-3
GO:0009296	flagellum assembly	8.934416e-3
GO:0033013	tetrapyrrole metabolic process	9.018703e-3
GO:0019637	organophosphate metabolic process	9.164403e-3
GO:0032608	interferon-beta production	9.254211e-3
GO:0042312	regulation of vasodilation	9.375786e-3
GO:0014029	neural crest formation	9.451365e-3
GO:0060807	regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification	9.519887e-3
GO:0045007	depurination	9.519887e-3
GO:0003142	cardiogenic plate morphogenesis	9.519887e-3
GO:0034971	histone H3-R17 methylation	9.935699e-3
GO:0009065	glutamine family amino acid catabolic process	9.947375e-3
GO:0016048	detection of temperature stimulus	9.949021e-3
GO:0014034	neural crest cell fate commitment	9.949021e-3
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.010063e-2
GO:0060479	lung cell differentiation	1.035113e-2
GO:0032229	negative regulation of synaptic transmission, GABAergic	1.036451e-2
GO:0006119	oxidative phosphorylation	1.036687e-2
GO:0044254	multicellular organismal protein catabolic process	1.050897e-2
GO:0016559	peroxisome fission	1.057795e-2
GO:0043266	regulation of potassium ion transport	1.067445e-2
GO:0070986	left/right axis specification	1.079195e-2
GO:0016476	regulation of embryonic cell shape	1.079195e-2
GO:0032288	myelin assembly	1.103500e-2
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	1.107442e-2
GO:0034014	response to triglyceride	1.121225e-2
GO:0034501	protein localization to kinetochore	1.122481e-2
GO:0051586	positive regulation of dopamine uptake	1.159721e-2
GO:0045454	cell redox homeostasis	1.176557e-2
GO:0019478	D-amino acid catabolic process	1.178805e-2
GO:0032241	positive regulation of nucleobase-containing compound transport	1.178805e-2
GO:0010986	positive regulation of lipoprotein particle clearance	1.178805e-2
GO:0009107	lipoate biosynthetic process	1.178805e-2
GO:0008298	intracellular mRNA localization	1.180329e-2
GO:0060712	spongiotrophoblast layer development	1.194928e-2
GO:0006901	vesicle coating	1.201682e-2
GO:0051793	medium-chain fatty acid catabolic process	1.205991e-2
GO:0070179	D-serine biosynthetic process	1.205991e-2
GO:0046629	gamma-delta T cell activation	1.205991e-2
GO:0023035	CD40 signaling pathway	1.205991e-2
GO:0010571	positive regulation of DNA replication involved in S phase	1.205991e-2
GO:0006188	IMP biosynthetic process	1.246604e-2
GO:0030573	bile acid catabolic process	1.246780e-2
GO:0046426	negative regulation of JAK-STAT cascade	1.249744e-2
GO:0048268	clathrin coat assembly	1.253260e-2
GO:0006412	translation	1.260596e-2
GO:0090224	regulation of spindle organization	1.261975e-2
GO:0046085	adenosine metabolic process	1.283152e-2
GO:0007288	sperm axoneme assembly	1.284588e-2
GO:0060271	cilium morphogenesis	1.300596e-2
GO:0008033	tRNA processing	1.307425e-2
GO:0051443	positive regulation of ubiquitin-protein ligase activity	1.319160e-2
GO:0002001	renin secretion into blood stream	1.350153e-2
GO:0009060	aerobic respiration	1.353456e-2
GO:0030174	regulation of DNA-dependent DNA replication initiation	1.358698e-2
GO:0006011	UDP-glucose metabolic process	1.358698e-2
GO:0071777	positive regulation of cell cycle cytokinesis	1.366110e-2
GO:0044272	sulfur compound biosynthetic process	1.377291e-2
GO:0060290	transdifferentiation	1.392811e-2
GO:0006346	methylation-dependent chromatin silencing	1.392811e-2
GO:0046502	uroporphyrinogen III metabolic process	1.397433e-2
GO:0006620	posttranslational protein targeting to membrane	1.414282e-2
GO:0090230	regulation of centromere complex assembly	1.429463e-2
GO:0043984	histone H4-K16 acetylation	1.429463e-2
GO:0033091	positive regulation of immature T cell proliferation	1.430815e-2
GO:0046952	ketone body catabolic process	1.432281e-2
GO:0060947	cardiac vascular smooth muscle cell differentiation	1.432281e-2
GO:0006104	succinyl-CoA metabolic process	1.432281e-2
GO:0071843	cellular component biogenesis at cellular level	1.432787e-2
GO:0033522	histone H2A ubiquitination	1.448164e-2
GO:0019673	GDP-mannose metabolic process	1.457206e-2
GO:0001881	receptor recycling	1.458882e-2
GO:0019509	L-methionine salvage from methylthioadenosine	1.461517e-2
GO:0008654	phospholipid biosynthetic process	1.468285e-2
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	1.475195e-2
GO:0006506	GPI anchor biosynthetic process	1.516026e-2
GO:0019395	fatty acid oxidation	1.532456e-2
GO:0015867	ATP transport	1.535465e-2
GO:0042255	ribosome assembly	1.558956e-2
GO:0021523	somatic motor neuron differentiation	1.564022e-2
GO:0043931	ossification involved in bone maturation	1.579810e-2
GO:0009451	RNA modification	1.603760e-2
GO:0016180	snRNA processing	1.633773e-2
GO:0032439	endosome localization	1.634833e-2
GO:0000237	leptotene	1.634833e-2
GO:0000715	nucleotide-excision repair, DNA damage recognition	1.637264e-2
GO:0035269	protein O-linked mannosylation	1.667075e-2
GO:0003222	ventricular trabecular myocardium morphogenesis	1.667075e-2
GO:0033153	T cell receptor V(D)J recombination	1.676179e-2
GO:0034421	post-translational protein acetylation	1.695479e-2
GO:0019254	carnitine metabolic process, CoA-linked	1.695479e-2
GO:0010735	positive regulation of transcription via serum response element binding	1.695479e-2
GO:0018344	protein geranylgeranylation	1.695479e-2
GO:0021932	hindbrain radial glia guided cell migration	1.765648e-2
GO:0018202	peptidyl-histidine modification	1.765648e-2
GO:0060674	placenta blood vessel development	1.782375e-2
GO:0002017	regulation of blood volume by renal aldosterone	1.818169e-2
GO:0006393	termination of mitochondrial transcription	1.821760e-2
GO:0034440	lipid oxidation	1.822556e-2
GO:0006544	glycine metabolic process	1.855543e-2
GO:0010950	positive regulation of endopeptidase activity	1.873165e-2
GO:0030223	neutrophil differentiation	1.873165e-2
GO:0000730	DNA recombinase assembly	1.873165e-2
GO:0043064	flagellum organization	1.882066e-2
GO:0032007	negative regulation of TOR signaling cascade	1.882066e-2
GO:0021952	central nervous system projection neuron axonogenesis	1.886998e-2
GO:0009437	carnitine metabolic process	1.926233e-2
GO:0048861	leukemia inhibitory factor signaling pathway	1.931508e-2
GO:0042637	catagen	1.938740e-2
GO:0051299	centrosome separation	1.957893e-2
GO:0033034	positive regulation of myeloid cell apoptosis	1.957893e-2
GO:0045741	positive regulation of epidermal growth factor-activated receptor activity	1.963640e-2
GO:0016482	cytoplasmic transport	1.970473e-2
GO:0090075	relaxation of muscle	2.034529e-2
GO:0010288	response to lead ion	2.053163e-2
GO:0021943	formation of radial glial scaffolds	2.130347e-2
GO:0051168	nuclear export	2.130888e-2
GO:0032239	regulation of nucleobase-containing compound transport	2.166797e-2
GO:0035412	regulation of catenin import into nucleus	2.167323e-2
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	2.182559e-2
GO:0007412	axon target recognition	2.182559e-2
GO:0045908	negative regulation of vasodilation	2.209462e-2
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.225990e-2
GO:0050651	dermatan sulfate proteoglycan biosynthetic process	2.233693e-2
GO:0034059	response to anoxia	2.233693e-2
GO:0015822	ornithine transport	2.247375e-2
GO:0051531	NFAT protein import into nucleus	2.247375e-2
GO:0042053	regulation of dopamine metabolic process	2.274892e-2
GO:0033131	regulation of glucokinase activity	2.310159e-2
GO:0019062	virion attachment to host cell surface receptor	2.310159e-2
GO:0043503	skeletal muscle fiber adaptation	2.322758e-2
GO:0007031	peroxisome organization	2.323919e-2
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	2.334886e-2
GO:2000300	regulation of synaptic vesicle exocytosis	2.361769e-2
GO:0060659	nipple sheath formation	2.377999e-2
GO:0060649	mammary gland bud elongation	2.377999e-2
GO:0000956	nuclear-transcribed mRNA catabolic process	2.383886e-2
GO:0070106	interleukin-27-mediated signaling pathway	2.387615e-2
GO:0045653	negative regulation of megakaryocyte differentiation	2.387615e-2
GO:0015868	purine ribonucleotide transport	2.387615e-2
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	2.411208e-2
GO:0048103	somatic stem cell division	2.418579e-2
GO:0035306	positive regulation of dephosphorylation	2.430345e-2
GO:0010944	negative regulation of transcription by competitive promoter binding	2.441723e-2
GO:0045739	positive regulation of DNA repair	2.476662e-2
GO:0071895	odontoblast differentiation	2.541605e-2
GO:0055099	response to high density lipoprotein particle stimulus	2.541605e-2
GO:0019532	oxalate transport	2.541605e-2
GO:0009069	serine family amino acid metabolic process	2.545549e-2
GO:0048002	antigen processing and presentation of peptide antigen	2.571680e-2
GO:0016095	polyprenol catabolic process	2.580596e-2
GO:0060209	estrus	2.580596e-2
GO:0097037	heme export	2.580596e-2
GO:0033262	regulation of DNA replication involved in S phase	2.580596e-2
GO:0006893	Golgi to plasma membrane transport	2.592363e-2
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.650836e-2
GO:0003285	septum secundum development	2.669954e-2
GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	2.685122e-2
GO:0010034	response to acetate	2.685122e-2
GO:0061017	hepatoblast differentiation	2.685122e-2
GO:0001561	fatty acid alpha-oxidation	2.703151e-2
GO:0009311	oligosaccharide metabolic process	2.740843e-2
GO:0032467	positive regulation of cytokinesis	2.773424e-2
GO:0006285	base-excision repair, AP site formation	2.774998e-2
GO:0042711	maternal behavior	2.774998e-2
GO:0017085	response to insecticide	2.790036e-2
GO:0042069	regulation of catecholamine metabolic process	2.820600e-2
GO:0002016	regulation of blood volume by renin-angiotensin	2.860774e-2
GO:2000016	negative regulation of determination of dorsal identity	2.864863e-2
GO:0050655	dermatan sulfate proteoglycan metabolic process	2.866910e-2
GO:0007260	tyrosine phosphorylation of STAT protein	2.872244e-2
GO:0032637	interleukin-8 production	2.912152e-2
GO:0090307	spindle assembly involved in mitosis	2.934885e-2
GO:0035330	regulation of hippo signaling cascade	2.934885e-2
GO:0032446	protein modification by small protein conjugation	2.951664e-2
GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process	2.965412e-2
GO:0045046	protein import into peroxisome membrane	2.965412e-2
GO:0009650	UV protection	2.981673e-2
GO:0033602	negative regulation of dopamine secretion	2.985867e-2
GO:0014002	astrocyte development	2.998168e-2
GO:0051488	activation of anaphase-promoting complex activity	3.023399e-2
GO:0035284	brain segmentation	3.023399e-2
GO:0007097	nuclear migration	3.069981e-2
GO:2000481	positive regulation of cAMP-dependent protein kinase activity	3.099265e-2
GO:2000534	positive regulation of renal albumin absorption	3.099265e-2
GO:0070845	polyubiquitinated misfolded protein transport	3.099265e-2
GO:2000478	positive regulation of metanephric glomerular visceral epithelial cell development	3.099265e-2
GO:2000461	negative regulation of eukaryotic cell surface binding	3.099265e-2
GO:0070994	detection of oxidative stress	3.099265e-2
GO:0060266	negative regulation of respiratory burst involved in inflammatory response	3.104252e-2
GO:0034470	ncRNA processing	3.105300e-2
GO:0018146	keratan sulfate biosynthetic process	3.105644e-2
GO:0070262	peptidyl-serine dephosphorylation	3.105644e-2
GO:0035307	positive regulation of protein dephosphorylation	3.123818e-2
GO:0001977	renal system process involved in regulation of blood volume	3.142959e-2
GO:0035721	intraflagellar retrograde transport	3.146039e-2
GO:0007206	activation of phospholipase C activity by metabotropic glutamate receptor signaling pathway	3.146039e-2
GO:0002005	angiotensin catabolic process in blood	3.146039e-2
GO:0006401	RNA catabolic process	3.170415e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0042268	regulation of cytolysis	3.230096e-10
GO:0006396	RNA processing	3.546372e-8
GO:0010989	negative regulation of low-density lipoprotein particle clearance	8.805467e-8
GO:0032200	telomere organization	1.092996e-7
GO:0030262	apoptotic nuclear change	1.421639e-7
GO:0000080	G1 phase of mitotic cell cycle	1.905590e-7
GO:0030263	apoptotic chromosome condensation	2.471705e-7
GO:0008535	respiratory chain complex IV assembly	2.992255e-7
GO:0045292	nuclear mRNA cis splicing, via spliceosome	3.644521e-7
GO:0032202	telomere assembly	8.073606e-7
GO:0010987	negative regulation of high-density lipoprotein particle clearance	8.270395e-7
GO:0010897	negative regulation of triglyceride catabolic process	8.270395e-7
GO:0010833	telomere maintenance via telomere lengthening	8.270395e-7
GO:0051661	maintenance of centrosome location	9.497356e-7
GO:0006921	cellular component disassembly involved in apoptosis	1.129852e-6
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.362110e-6
GO:0006259	DNA metabolic process	1.513150e-6
GO:0006409	tRNA export from nucleus	2.364156e-6
GO:0045919	positive regulation of cytolysis	2.932400e-6
GO:0001843	neural tube closure	3.805989e-6
GO:0071103	DNA conformation change	3.993005e-6
GO:0032781	positive regulation of ATPase activity	4.192210e-6
GO:0048239	negative regulation of DNA recombination at telomere	4.309749e-6
GO:0006430	lysyl-tRNA aminoacylation	4.309749e-6
GO:0044260	cellular macromolecule metabolic process	4.649259e-6
GO:0060621	negative regulation of cholesterol import	5.817651e-6
GO:0000422	mitochondrion degradation	5.937728e-6
GO:0070979	protein K11-linked ubiquitination	7.527322e-6
GO:0051318	G1 phase	7.849997e-6
GO:0006261	DNA-dependent DNA replication	8.574537e-6
GO:0018293	protein-FAD linkage	8.773007e-6
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	8.773007e-6
GO:0060606	tube closure	1.008110e-5
GO:0010982	regulation of high-density lipoprotein particle clearance	1.098907e-5
GO:0045918	negative regulation of cytolysis	1.194382e-5
GO:0046498	S-adenosylhomocysteine metabolic process	1.217481e-5
GO:0008380	RNA splicing	1.268434e-5
GO:0000723	telomere maintenance	1.420368e-5
GO:0006493	protein O-linked glycosylation	1.593705e-5
GO:0018192	enzyme active site formation via L-cysteine persulfide	1.661061e-5
GO:0016071	mRNA metabolic process	1.671145e-5
GO:0060620	regulation of cholesterol import	1.722738e-5
GO:0000395	nuclear mRNA 5'-splice site recognition	1.839405e-5
GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	2.388896e-5
GO:0022411	cellular component disassembly	2.595021e-5
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	3.040141e-5
GO:0035799	ureter maturation	3.138323e-5
GO:2000597	positive regulation of optic nerve formation	3.138323e-5
GO:0061360	optic chiasma development	3.138323e-5
GO:0021650	vestibulocochlear nerve formation	3.138323e-5
GO:0021633	optic nerve structural organization	3.138323e-5
GO:0071845	cellular component disassembly at cellular level	3.151159e-5
GO:0051168	nuclear export	3.301478e-5
GO:0042661	regulation of mesodermal cell fate specification	3.377637e-5
GO:0050713	negative regulation of interleukin-1 beta secretion	3.674767e-5
GO:0048378	regulation of lateral mesodermal cell fate specification	3.759862e-5
GO:0050821	protein stabilization	3.990122e-5
GO:0003350	pulmonary myocardium development	4.196679e-5
GO:0000189	MAPK import into nucleus	5.228933e-5
GO:0010994	free ubiquitin chain polymerization	5.228933e-5
GO:0090304	nucleic acid metabolic process	5.331666e-5
GO:0050711	negative regulation of interleukin-1 secretion	5.652502e-5
GO:0031848	protection from non-homologous end joining at telomere	5.967389e-5
GO:0048352	paraxial mesoderm structural organization	6.180309e-5
GO:0021998	neural plate mediolateral regionalization	6.180309e-5
GO:0032203	telomere formation via telomerase	6.180309e-5
GO:0006268	DNA unwinding involved in replication	6.374626e-5
GO:0032872	regulation of stress-activated MAPK cascade	6.439877e-5
GO:0006397	mRNA processing	6.537798e-5
GO:0033235	positive regulation of protein sumoylation	7.031165e-5
GO:0014020	primary neural tube formation	7.424806e-5
GO:0031536	positive regulation of exit from mitosis	7.745289e-5
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	7.796162e-5
GO:0015966	diadenosine tetraphosphate biosynthetic process	7.822259e-5
GO:2000380	regulation of mesoderm development	8.566635e-5
GO:0051973	positive regulation of telomerase activity	8.831193e-5
GO:0042559	pteridine-containing compound biosynthetic process	9.199051e-5
GO:0006290	pyrimidine dimer repair	1.000476e-4
GO:0032218	riboflavin transport	1.156662e-4
GO:0046654	tetrahydrofolate biosynthetic process	1.276407e-4
GO:0060266	negative regulation of respiratory burst involved in inflammatory response	1.290115e-4
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	1.805922e-4
GO:0072355	histone H3-T3 phosphorylation	1.939719e-4
GO:0051891	positive regulation of cardioblast differentiation	1.959530e-4
GO:0006308	DNA catabolic process	2.130872e-4
GO:0006323	DNA packaging	2.134307e-4
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	2.147217e-4
GO:0022417	protein maturation by protein folding	2.147217e-4
GO:0007492	endoderm development	2.197550e-4
GO:0051684	maintenance of Golgi location	2.378036e-4
GO:0070165	positive regulation of adiponectin secretion	2.378036e-4
GO:0033617	mitochondrial respiratory chain complex IV assembly	2.378036e-4
GO:0033031	positive regulation of neutrophil apoptosis	2.378036e-4
GO:0046452	dihydrofolate metabolic process	2.378036e-4
GO:0072003	kidney rudiment formation	2.506174e-4
GO:0019348	dolichol metabolic process	2.506174e-4
GO:0032205	negative regulation of telomere maintenance	2.677094e-4
GO:0042696	menarche	2.775110e-4
GO:0035269	protein O-linked mannosylation	2.788677e-4
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	2.806907e-4
GO:0090209	negative regulation of triglyceride metabolic process	3.103868e-4
GO:0072221	metanephric distal convoluted tubule development	3.234765e-4
GO:0030071	regulation of mitotic metaphase/anaphase transition	3.304388e-4
GO:0007501	mesodermal cell fate specification	3.322929e-4
GO:0048340	paraxial mesoderm morphogenesis	3.460771e-4
GO:0006139	nucleobase-containing compound metabolic process	3.552254e-4
GO:0046653	tetrahydrofolate metabolic process	3.596875e-4
GO:0002740	negative regulation of cytokine secretion involved in immune response	3.596875e-4
GO:0045175	basal protein localization	3.701858e-4
GO:0044237	cellular metabolic process	3.750731e-4
GO:0000398	nuclear mRNA splicing, via spliceosome	3.765251e-4
GO:0006403	RNA localization	3.771972e-4
GO:0019359	nicotinamide nucleotide biosynthetic process	3.901182e-4
GO:0006974	response to DNA damage stimulus	3.946184e-4
GO:0003406	retinal pigment epithelium development	3.987054e-4
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	4.059123e-4
GO:0034660	ncRNA metabolic process	4.077618e-4
GO:0031647	regulation of protein stability	4.100671e-4
GO:0006264	mitochondrial DNA replication	4.149074e-4
GO:0000278	mitotic cell cycle	4.183595e-4
GO:0032508	DNA duplex unwinding	4.391894e-4
GO:0070286	axonemal dynein complex assembly	4.584948e-4
GO:0021759	globus pallidus development	4.705737e-4
GO:0048285	organelle fission	4.867015e-4
GO:0034470	ncRNA processing	5.090269e-4
GO:0000375	RNA splicing, via transesterification reactions	5.822971e-4
GO:0032392	DNA geometric change	5.888058e-4
GO:0046103	inosine biosynthetic process	6.014729e-4
GO:0016191	synaptic vesicle uncoating	6.014729e-4
GO:0006154	adenosine catabolic process	6.014729e-4
GO:0034380	high-density lipoprotein particle assembly	6.024832e-4
GO:0042335	cuticle development	6.036606e-4
GO:0007004	telomere maintenance via telomerase	6.210630e-4
GO:0051169	nuclear transport	6.428878e-4
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	6.653348e-4
GO:0060975	cardioblast migration to the midline involved in heart field formation	6.653348e-4
GO:0003210	cardiac atrium formation	6.653348e-4
GO:0009159	deoxyribonucleoside monophosphate catabolic process	6.653348e-4
GO:0003259	cardioblast anterior-lateral migration	6.653348e-4
GO:0003236	sinus venosus morphogenesis	6.653348e-4
GO:0021877	forebrain neuron fate commitment	6.814180e-4
GO:0050658	RNA transport	6.880290e-4
GO:0022403	cell cycle phase	7.370865e-4
GO:0045347	negative regulation of MHC class II biosynthetic process	7.544957e-4
GO:0030719	P granule organization	7.544957e-4
GO:0070194	synaptonemal complex disassembly	7.551744e-4
GO:0035674	tricarboxylic acid transmembrane transport	7.551744e-4
GO:0007183	SMAD protein complex assembly	7.573193e-4
GO:0007094	mitotic cell cycle spindle assembly checkpoint	7.598637e-4
GO:0007131	reciprocal meiotic recombination	7.700573e-4
GO:0046474	glycerophospholipid biosynthetic process	7.857391e-4
GO:0051188	cofactor biosynthetic process	7.866072e-4
GO:0006913	nucleocytoplasmic transport	8.352505e-4
GO:2000971	negative regulation of detection of glucose	8.860138e-4
GO:0006545	glycine biosynthetic process	8.860138e-4
GO:2000976	regulation of transcription from RNA polymerase II promoter involved in detection of glucose	8.860138e-4
GO:0006189	'de novo' IMP biosynthetic process	8.860138e-4
GO:0000433	negative regulation of transcription from RNA polymerase II promoter by glucose	8.860138e-4
GO:0048339	paraxial mesoderm development	8.967281e-4
GO:0071174	mitotic cell cycle spindle checkpoint	9.180154e-4
GO:0000819	sister chromatid segregation	9.604638e-4
GO:0072177	mesonephric duct development	9.632220e-4
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	9.739874e-4
GO:0006412	translation	9.819052e-4
GO:0072305	negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis	1.009564e-3
GO:2000594	positive regulation of metanephric DCT cell differentiation	1.009564e-3
GO:0039003	pronephric field specification	1.009564e-3
GO:0006383	transcription from RNA polymerase III promoter	1.017895e-3
GO:0043045	DNA methylation involved in embryo development	1.017895e-3
GO:0006269	DNA replication, synthesis of RNA primer	1.017895e-3
GO:0006405	RNA export from nucleus	1.043264e-3
GO:0010896	regulation of triglyceride catabolic process	1.075595e-3
GO:0008637	apoptotic mitochondrial changes	1.083126e-3
GO:0051450	myoblast proliferation	1.084586e-3
GO:0048368	lateral mesoderm development	1.102629e-3
GO:0006281	DNA repair	1.141342e-3
GO:0070198	protein localization to chromosome, telomeric region	1.192302e-3
GO:0010985	negative regulation of lipoprotein particle clearance	1.202282e-3
GO:0051586	positive regulation of dopamine uptake	1.232540e-3
GO:0048382	mesendoderm development	1.232540e-3
GO:0072171	mesonephric tubule morphogenesis	1.269372e-3
GO:0016068	type I hypersensitivity	1.288098e-3
GO:0061017	hepatoblast differentiation	1.295539e-3
GO:0019049	evasion of host defenses by virus	1.295539e-3
GO:0021562	vestibulocochlear nerve development	1.329120e-3
GO:0007412	axon target recognition	1.329120e-3
GO:0006784	heme a biosynthetic process	1.329120e-3
GO:0033233	regulation of protein sumoylation	1.369141e-3
GO:0046102	inosine metabolic process	1.383196e-3
GO:0034641	cellular nitrogen compound metabolic process	1.393626e-3
GO:0009786	regulation of asymmetric cell division	1.448151e-3
GO:0021915	neural tube development	1.563386e-3
GO:0019438	aromatic compound biosynthetic process	1.586692e-3
GO:0032914	positive regulation of transforming growth factor beta1 production	1.631073e-3
GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly	1.631073e-3
GO:0002098	tRNA wobble uridine modification	1.631073e-3
GO:2000078	positive regulation of type B pancreatic cell development	1.676695e-3
GO:0042747	circadian sleep/wake cycle, REM sleep	1.676695e-3
GO:0032289	central nervous system myelin formation	1.676695e-3
GO:0009435	NAD biosynthetic process	1.689185e-3
GO:0070534	protein K63-linked ubiquitination	1.717583e-3
GO:0035566	regulation of metanephros size	1.724080e-3
GO:0007067	mitosis	1.756350e-3
GO:0046785	microtubule polymerization	1.799289e-3
GO:0042773	ATP synthesis coupled electron transport	1.804776e-3
GO:0021797	forebrain anterior/posterior pattern specification	1.879809e-3
GO:0032874	positive regulation of stress-activated MAPK cascade	1.879809e-3
GO:0043488	regulation of mRNA stability	1.899508e-3
GO:0071636	positive regulation of transforming growth factor beta production	1.920799e-3
GO:0060795	cell fate commitment involved in formation of primary germ layers	1.938312e-3
GO:0030300	regulation of intestinal cholesterol absorption	1.975491e-3
GO:0000279	M phase	1.995825e-3
GO:0009108	coenzyme biosynthetic process	2.015046e-3
GO:0044340	canonical Wnt receptor signaling pathway involved in regulation of cell proliferation	2.032784e-3
GO:0046499	S-adenosylmethioninamine metabolic process	2.032784e-3
GO:0018158	protein oxidation	2.054795e-3
GO:0061011	hepatic duct development	2.054795e-3
GO:0010825	positive regulation of centrosome duplication	2.054795e-3
GO:0006713	glucocorticoid catabolic process	2.054795e-3
GO:0000722	telomere maintenance via recombination	2.054795e-3
GO:0071173	spindle assembly checkpoint	2.078100e-3
GO:0042558	pteridine-containing compound metabolic process	2.092340e-3
GO:0034227	tRNA thio-modification	2.206208e-3
GO:0008078	mesodermal cell migration	2.220348e-3
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	2.235815e-3
GO:0090074	negative regulation of protein homodimerization activity	2.235815e-3
GO:0016559	peroxisome fission	2.235815e-3
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	2.235815e-3
GO:0045769	negative regulation of asymmetric cell division	2.261617e-3
GO:0009443	pyridoxal 5'-phosphate salvage	2.261617e-3
GO:0007549	dosage compensation	2.409898e-3
GO:0007265	Ras protein signal transduction	2.448918e-3
GO:0000087	M phase of mitotic cell cycle	2.454278e-3
GO:0007096	regulation of exit from mitosis	2.546585e-3
GO:0048793	pronephros development	2.570717e-3
GO:0034377	plasma lipoprotein particle assembly	2.601777e-3
GO:0051890	regulation of cardioblast differentiation	2.679199e-3
GO:0048854	brain morphogenesis	2.692734e-3
GO:0060928	atrioventricular node cell development	2.702330e-3
GO:0019858	cytosine metabolic process	2.702330e-3
GO:0060929	atrioventricular node cell fate commitment	2.702330e-3
GO:0003168	cardiac Purkinje fiber cell differentiation	2.702330e-3
GO:0003342	proepicardium development	2.702330e-3
GO:0030950	establishment or maintenance of actin cytoskeleton polarity	2.766808e-3
GO:0010608	posttranscriptional regulation of gene expression	2.776061e-3
GO:0072172	mesonephric tubule formation	2.782029e-3
GO:0014051	gamma-aminobutyric acid secretion	2.782029e-3
GO:0071459	protein localization to chromosome, centromeric region	2.788053e-3
GO:0060192	negative regulation of lipase activity	2.878727e-3
GO:0006561	proline biosynthetic process	2.928367e-3
GO:0051594	detection of glucose	2.928367e-3
GO:0003349	epicardium-derived cardiac endothelial cell differentiation	2.928367e-3
GO:0043949	regulation of cAMP-mediated signaling	2.937425e-3
GO:0007346	regulation of mitotic cell cycle	2.974226e-3
GO:0034622	cellular macromolecular complex assembly	2.994607e-3
GO:0022402	cell cycle process	3.016909e-3
GO:0048255	mRNA stabilization	3.057280e-3
GO:0042473	outer ear morphogenesis	3.058606e-3
GO:0000002	mitochondrial genome maintenance	3.058606e-3
GO:0034314	Arp2/3 complex-mediated actin nucleation	3.107676e-3
GO:0016266	O-glycan processing	3.107676e-3
GO:0010388	cullin deneddylation	3.154453e-3
GO:0007049	cell cycle	3.332452e-3
GO:0010984	regulation of lipoprotein particle clearance	3.337116e-3
GO:0032908	regulation of transforming growth factor beta1 production	3.402659e-3
GO:0000070	mitotic sister chromatid segregation	3.434015e-3
GO:0046015	regulation of transcription by glucose	3.443697e-3
GO:0043487	regulation of RNA stability	3.457778e-3
GO:0042775	mitochondrial ATP synthesis coupled electron transport	3.669388e-3
GO:0006260	DNA replication	3.688115e-3
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	3.701118e-3
GO:0007127	meiosis I	3.703448e-3
GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	3.757152e-3
GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	3.757152e-3
GO:0070935	3'-UTR-mediated mRNA stabilization	3.757152e-3
GO:0001705	ectoderm formation	3.773762e-3
GO:0051005	negative regulation of lipoprotein lipase activity	3.790728e-3
GO:0072017	distal tubule development	3.795113e-3
GO:0032488	Cdc42 protein signal transduction	3.852698e-3
GO:0007028	cytoplasm organization	3.979246e-3
GO:0051235	maintenance of location	4.096341e-3
GO:0001710	mesodermal cell fate commitment	4.166219e-3
GO:0045910	negative regulation of DNA recombination	4.214475e-3
GO:0007076	mitotic chromosome condensation	4.214516e-3
GO:0043543	protein acylation	4.241303e-3
GO:0090207	regulation of triglyceride metabolic process	4.242389e-3
GO:0032515	negative regulation of phosphoprotein phosphatase activity	4.249132e-3
GO:0035282	segmentation	4.279076e-3
GO:0070508	cholesterol import	4.302050e-3
GO:0060264	regulation of respiratory burst involved in inflammatory response	4.304530e-3
GO:0007256	activation of JNKK activity	4.330735e-3
GO:0043666	regulation of phosphoprotein phosphatase activity	4.371684e-3
GO:0006807	nitrogen compound metabolic process	4.382339e-3
GO:0045717	negative regulation of fatty acid biosynthetic process	4.473849e-3
GO:0032472	Golgi calcium ion transport	4.500011e-3
GO:0032468	Golgi calcium ion homeostasis	4.500011e-3
GO:0008208	C21-steroid hormone catabolic process	4.500011e-3
GO:0030026	cellular manganese ion homeostasis	4.500011e-3
GO:0070163	regulation of adiponectin secretion	4.539464e-3
GO:0009798	axis specification	4.555962e-3
GO:0010467	gene expression	4.654401e-3
GO:0021871	forebrain regionalization	4.747068e-3
GO:0031577	spindle checkpoint	4.773022e-3
GO:0033132	negative regulation of glucokinase activity	4.792150e-3
GO:0043687	post-translational protein modification	4.855934e-3
GO:0021798	forebrain dorsal/ventral pattern formation	4.855934e-3
GO:0048012	hepatocyte growth factor receptor signaling pathway	4.857000e-3
GO:0006302	double-strand break repair	4.926992e-3
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	4.935856e-3
GO:0018065	protein-cofactor linkage	4.987639e-3
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	5.012406e-3
GO:0043491	protein kinase B signaling cascade	5.080781e-3
GO:0019673	GDP-mannose metabolic process	5.267408e-3
GO:0017004	cytochrome complex assembly	5.267408e-3
GO:0046079	dUMP catabolic process	5.297337e-3
GO:0017126	nucleologenesis	5.297337e-3
GO:0051004	regulation of lipoprotein lipase activity	5.497837e-3
GO:0072070	loop of Henle development	5.624536e-3
GO:0001836	release of cytochrome c from mitochondria	5.678201e-3
GO:0042538	hyperosmotic salinity response	5.707466e-3
GO:0016567	protein ubiquitination	5.808704e-3
GO:0045185	maintenance of protein location	6.010942e-3
GO:0016072	rRNA metabolic process	6.065241e-3
GO:0050774	negative regulation of dendrite morphogenesis	6.101687e-3
GO:0032486	Rap protein signal transduction	6.101687e-3
GO:0006777	Mo-molybdopterin cofactor biosynthetic process	6.128463e-3
GO:0021670	lateral ventricle development	6.139871e-3
GO:0006611	protein export from nucleus	6.275103e-3
GO:0015746	citrate transport	6.284588e-3
GO:0034421	post-translational protein acetylation	6.284588e-3
GO:0009817	defense response to fungus, incompatible interaction	6.284588e-3
GO:0008216	spermidine metabolic process	6.284588e-3
GO:0070193	synaptonemal complex organization	6.303839e-3
GO:0072078	nephron tubule morphogenesis	6.332404e-3
GO:0003002	regionalization	6.335965e-3
GO:0030261	chromosome condensation	6.540852e-3
GO:0032873	negative regulation of stress-activated MAPK cascade	6.570885e-3
GO:0007509	mesoderm migration involved in gastrulation	6.570885e-3
GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	6.637489e-3
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	6.747996e-3
GO:0009396	folic acid-containing compound biosynthetic process	6.824514e-3
GO:0007141	male meiosis I	6.875846e-3
GO:0060430	lung saccule development	6.888398e-3
GO:0070368	positive regulation of hepatocyte differentiation	7.062324e-3
GO:0042664	negative regulation of endodermal cell fate specification	7.062324e-3
GO:0021764	amygdala development	7.062324e-3
GO:0030878	thyroid gland development	7.077964e-3
GO:0042796	snRNA transcription from RNA polymerase III promoter	7.143358e-3
GO:0042795	snRNA transcription from RNA polymerase II promoter	7.143358e-3
GO:0035871	protein K11-linked deubiquitination	7.143358e-3
GO:0051329	interphase of mitotic cell cycle	7.156389e-3
GO:0021591	ventricular system development	7.247397e-3
GO:0016311	dephosphorylation	7.326174e-3
GO:0051325	interphase	7.359875e-3
GO:0032446	protein modification by small protein conjugation	7.371449e-3
GO:0097039	protein linear polyubiquitination	7.430921e-3
GO:0032811	negative regulation of epinephrine secretion	7.430921e-3
GO:0006297	nucleotide-excision repair, DNA gap filling	7.430921e-3
GO:2000300	regulation of synaptic vesicle exocytosis	7.503747e-3
GO:0060177	regulation of angiotensin metabolic process	7.503747e-3
GO:0071922	regulation of cohesin localization to chromatin	7.503747e-3
GO:0090009	primitive streak formation	7.516221e-3
GO:0006473	protein acetylation	7.611804e-3
GO:0006560	proline metabolic process	7.676205e-3
GO:0050768	negative regulation of neurogenesis	7.738810e-3
GO:0045922	negative regulation of fatty acid metabolic process	7.896568e-3
GO:0006470	protein dephosphorylation	7.911080e-3
GO:0051651	maintenance of location in cell	7.915543e-3
GO:0006334	nucleosome assembly	7.934340e-3
GO:0060044	negative regulation of cardiac muscle cell proliferation	7.957828e-3
GO:0072202	cell differentiation involved in metanephros development	7.997590e-3
GO:0002719	negative regulation of cytokine production involved in immune response	7.997590e-3
GO:0065005	protein-lipid complex assembly	8.090819e-3
GO:0031023	microtubule organizing center organization	8.131929e-3
GO:0051488	activation of anaphase-promoting complex activity	8.213058e-3
GO:0050995	negative regulation of lipid catabolic process	8.332421e-3
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	8.512494e-3
GO:0015959	diadenosine polyphosphate metabolic process	8.512494e-3
GO:0035695	mitochondrion degradation by induced vacuole formation	8.512494e-3
GO:0008631	induction of apoptosis by oxidative stress	8.557823e-3
GO:0040029	regulation of gene expression, epigenetic	8.594534e-3
GO:0061205	paramesonephric duct development	8.792744e-3
GO:0001841	neural tube formation	8.889551e-3
GO:0006244	pyrimidine nucleotide catabolic process	9.093330e-3
GO:0072040	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis	9.152396e-3
GO:0033127	regulation of histone phosphorylation	9.152396e-3
GO:0050883	musculoskeletal movement, spinal reflex action	9.152396e-3
GO:0000209	protein polyubiquitination	9.342068e-3
GO:0045017	glycerolipid biosynthetic process	9.411666e-3
GO:0022011	myelination in peripheral nervous system	9.481794e-3
GO:0051301	cell division	9.795292e-3
GO:0042278	purine nucleoside metabolic process	9.923107e-3
GO:2000682	positive regulation of rubidium ion transport	9.929339e-3
GO:2000688	positive regulation of rubidium ion transmembrane transporter activity	9.929339e-3
GO:0048227	plasma membrane to endosome transport	9.929339e-3
GO:0010430	fatty acid omega-oxidation	9.929339e-3
GO:0035826	rubidium ion transport	9.929339e-3
GO:0002502	peptide antigen assembly with MHC class I protein complex	9.929339e-3
GO:0032065	cortical protein anchoring	9.929339e-3
GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	1.024259e-2
GO:0071539	protein localization to centrosome	1.036188e-2
GO:0071233	cellular response to leucine	1.036188e-2
GO:0060339	negative regulation of type I interferon-mediated signaling pathway	1.036188e-2
GO:0034048	negative regulation of protein phosphatase type 2A activity	1.036188e-2
GO:0009051	pentose-phosphate shunt, oxidative branch	1.043292e-2
GO:0001963	synaptic transmission, dopaminergic	1.062614e-2
GO:0019363	pyridine nucleotide biosynthetic process	1.062806e-2
GO:0007091	mitotic metaphase/anaphase transition	1.083010e-2
GO:0047496	vesicle transport along microtubule	1.084464e-2
GO:0002513	tolerance induction to self antigen	1.101233e-2
GO:0035564	regulation of kidney size	1.107047e-2
GO:0043248	proteasome assembly	1.108682e-2
GO:0051972	regulation of telomerase activity	1.108682e-2
GO:0003062	regulation of heart rate by chemical signal	1.108682e-2
GO:0014053	negative regulation of gamma-aminobutyric acid secretion	1.123205e-2
GO:0071422	succinate transmembrane transport	1.123205e-2
GO:0033129	positive regulation of histone phosphorylation	1.123205e-2
GO:0016340	calcium-dependent cell-matrix adhesion	1.123205e-2
GO:0002003	angiotensin maturation	1.123205e-2
GO:0006481	C-terminal protein methylation	1.123205e-2
GO:0007144	female meiosis I	1.123205e-2
GO:0042147	retrograde transport, endosome to Golgi	1.132271e-2
GO:0021532	neural tube patterning	1.137807e-2
GO:0045833	negative regulation of lipid metabolic process	1.144440e-2
GO:0090305	nucleic acid phosphodiester bond hydrolysis	1.161821e-2
GO:0045930	negative regulation of mitotic cell cycle	1.170662e-2
GO:0070507	regulation of microtubule cytoskeleton organization	1.173042e-2
GO:0030952	establishment or maintenance of cytoskeleton polarity	1.186493e-2
GO:0072162	metanephric mesenchymal cell differentiation	1.186493e-2
GO:0072079	nephron tubule formation	1.197608e-2
GO:0021604	cranial nerve structural organization	1.209401e-2
GO:0007129	synapsis	1.226462e-2
GO:0002739	regulation of cytokine secretion involved in immune response	1.232118e-2
GO:0010721	negative regulation of cell development	1.234527e-2
GO:0051055	negative regulation of lipid biosynthetic process	1.237265e-2
GO:0010458	exit from mitosis	1.237848e-2
GO:0007088	regulation of mitosis	1.265500e-2
GO:0009586	rhodopsin mediated phototransduction	1.272446e-2
GO:0001880	Mullerian duct regression	1.272446e-2
GO:0007020	microtubule nucleation	1.288467e-2
GO:0002326	B cell lineage commitment	1.288467e-2
GO:0070842	aggresome assembly	1.293444e-2
GO:0043985	histone H4-R3 methylation	1.293444e-2
GO:0022613	ribonucleoprotein complex biogenesis	1.296251e-2
GO:0015931	nucleobase-containing compound transport	1.300257e-2
GO:0051865	protein autoubiquitination	1.310845e-2
GO:0050710	negative regulation of cytokine secretion	1.310845e-2
GO:0010470	regulation of gastrulation	1.313713e-2
GO:0006007	glucose catabolic process	1.314832e-2
GO:0060947	cardiac vascular smooth muscle cell differentiation	1.315516e-2
GO:0032507	maintenance of protein location in cell	1.337070e-2
GO:0032353	negative regulation of hormone biosynthetic process	1.341915e-2
GO:0071843	cellular component biogenesis at cellular level	1.363934e-2
GO:0071243	cellular response to arsenic-containing substance	1.367136e-2
GO:2000543	positive regulation of gastrulation	1.384024e-2
GO:0072086	specification of loop of Henle identity	1.406998e-2
GO:0007099	centriole replication	1.406998e-2
GO:0006364	rRNA processing	1.425946e-2
GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	1.448791e-2
GO:0003241	growth involved in heart morphogenesis	1.451543e-2
GO:0051647	nucleus localization	1.452751e-2
GO:0070647	protein modification by small protein conjugation or removal	1.467229e-2
GO:0033044	regulation of chromosome organization	1.470232e-2
GO:0048268	clathrin coat assembly	1.475576e-2
GO:0003310	pancreatic A cell differentiation	1.475576e-2
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	1.484925e-2
GO:0040016	embryonic cleavage	1.485041e-2
GO:0006729	tetrahydrobiopterin biosynthetic process	1.485041e-2
GO:0002701	negative regulation of production of molecular mediator of immune response	1.514020e-2
GO:0048259	regulation of receptor-mediated endocytosis	1.527264e-2
GO:0035886	vascular smooth muscle cell differentiation	1.527462e-2
GO:0022904	respiratory electron transport chain	1.527462e-2
GO:0060486	Clara cell differentiation	1.549989e-2
GO:0065004	protein-DNA complex assembly	1.555359e-2
GO:0003166	bundle of His development	1.560187e-2
GO:0003218	cardiac left ventricle formation	1.567336e-2
GO:0021658	rhombomere 3 morphogenesis	1.570151e-2
GO:0006188	IMP biosynthetic process	1.570151e-2
GO:0043170	macromolecule metabolic process	1.575949e-2
GO:0031274	positive regulation of pseudopodium assembly	1.579727e-2
GO:0006659	phosphatidylserine biosynthetic process	1.579727e-2
GO:0006312	mitotic recombination	1.582729e-2
GO:0001845	phagolysosome assembly	1.582729e-2
GO:0021795	cerebral cortex cell migration	1.593598e-2
GO:0008334	histone mRNA metabolic process	1.612924e-2
GO:0006901	vesicle coating	1.612924e-2
GO:0070192	chromosome organization involved in meiosis	1.613861e-2
GO:0060381	positive regulation of single-stranded telomeric DNA binding	1.629023e-2
GO:0060816	random inactivation of X chromosome	1.629023e-2
GO:0006256	UDP catabolic process	1.629023e-2
GO:0045004	DNA replication proofreading	1.629023e-2
GO:2000657	negative regulation of apolipoprotein binding	1.629023e-2
GO:0043538	regulation of actin phosphorylation	1.629023e-2
GO:0010189	vitamin E biosynthetic process	1.629023e-2
GO:0034721	histone H3-K4 demethylation, trimethyl-H3-K4-specific	1.629023e-2
GO:0043046	DNA methylation involved in gamete generation	1.638171e-2
GO:0006891	intra-Golgi vesicle-mediated transport	1.638171e-2
GO:0048261	negative regulation of receptor-mediated endocytosis	1.657030e-2
GO:0021522	spinal cord motor neuron differentiation	1.660885e-2
GO:0090102	cochlea development	1.664092e-2