Novel motif:105

name:	motif105_KTNGNAGWMG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0030277	maintenance of gastrointestinal epithelium	1.083031e-14
GO:0006434	seryl-tRNA aminoacylation	1.187150e-14
GO:0010669	epithelial structure maintenance	8.553148e-13
GO:0071173	spindle assembly checkpoint	5.308361e-11
GO:0031577	spindle checkpoint	5.430510e-11
GO:0007094	mitotic cell cycle spindle assembly checkpoint	7.865045e-11
GO:0071174	mitotic cell cycle spindle checkpoint	1.457188e-10
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	2.936678e-10
GO:0030071	regulation of mitotic metaphase/anaphase transition	3.753665e-9
GO:0042475	odontogenesis of dentine-containing tooth	4.569977e-8
GO:0006569	tryptophan catabolic process	5.224296e-8
GO:0016056	rhodopsin mediated signaling pathway	5.966048e-8
GO:0045839	negative regulation of mitosis	6.566858e-8
GO:0006568	tryptophan metabolic process	6.604327e-8
GO:0032534	regulation of microvillus assembly	6.605532e-8
GO:0016032	viral reproduction	7.538022e-8
GO:0048378	regulation of lateral mesodermal cell fate specification	8.325508e-8
GO:0048075	positive regulation of eye pigmentation	1.269605e-7
GO:0061077	chaperone-mediated protein folding	1.386243e-7
GO:0033634	positive regulation of cell-cell adhesion mediated by integrin	3.422905e-7
GO:0009586	rhodopsin mediated phototransduction	5.748707e-7
GO:0006767	water-soluble vitamin metabolic process	6.348196e-7
GO:0010569	regulation of double-strand break repair via homologous recombination	6.463210e-7
GO:0071338	positive regulation of hair follicle cell proliferation	9.154344e-7
GO:0048073	regulation of eye pigmentation	1.652175e-6
GO:0006369	termination of RNA polymerase II transcription	1.906713e-6
GO:0032530	regulation of microvillus organization	2.094396e-6
GO:0007040	lysosome organization	2.878310e-6
GO:0022600	digestive system process	2.999190e-6
GO:0070189	kynurenine metabolic process	3.288745e-6
GO:0008582	regulation of synaptic growth at neuromuscular junction	3.808069e-6
GO:0002502	peptide antigen assembly with MHC class I protein complex	3.875621e-6
GO:0060789	hair follicle placode formation	3.878568e-6
GO:0006403	RNA localization	4.192861e-6
GO:0070389	chaperone cofactor-dependent protein refolding	4.509887e-6
GO:0043206	fibril organization	4.712392e-6
GO:0006457	protein folding	4.771998e-6
GO:2000119	negative regulation of sodium-dependent phosphate transport	7.059253e-6
GO:0051028	mRNA transport	7.067496e-6
GO:0009074	aromatic amino acid family catabolic process	7.117668e-6
GO:0035621	ER to Golgi ceramide transport	7.196793e-6
GO:0048352	paraxial mesoderm structural organization	8.110212e-6
GO:0021998	neural plate mediolateral regionalization	8.110212e-6
GO:0051534	negative regulation of NFAT protein import into nucleus	8.842522e-6
GO:0031214	biomineral tissue development	8.905649e-6
GO:0060788	ectodermal placode formation	9.113964e-6
GO:0034660	ncRNA metabolic process	9.156779e-6
GO:0006552	leucine catabolic process	9.185715e-6
GO:0007586	digestion	9.514260e-6
GO:0019439	aromatic compound catabolic process	1.022608e-5
GO:0040032	post-embryonic body morphogenesis	1.103431e-5
GO:0070584	mitochondrion morphogenesis	1.116661e-5
GO:0070831	basement membrane assembly	1.177286e-5
GO:0007603	phototransduction, visible light	1.194155e-5
GO:0018208	peptidyl-proline modification	1.435461e-5
GO:0035088	establishment or maintenance of apical/basal cell polarity	1.591339e-5
GO:0071816	tail-anchored membrane protein insertion into ER membrane	1.686066e-5
GO:0050821	protein stabilization	1.787845e-5
GO:0007033	vacuole organization	1.869223e-5
GO:0000966	RNA 5'-end processing	1.884377e-5
GO:0048382	mesendoderm development	2.107356e-5
GO:0006551	leucine metabolic process	2.385536e-5
GO:0051168	nuclear export	2.803129e-5
GO:0006259	DNA metabolic process	3.379767e-5
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	3.555885e-5
GO:0021798	forebrain dorsal/ventral pattern formation	3.764020e-5
GO:0019441	tryptophan catabolic process to kynurenine	3.767927e-5
GO:0050658	RNA transport	3.926287e-5
GO:0065004	protein-DNA complex assembly	3.966087e-5
GO:0031647	regulation of protein stability	4.023859e-5
GO:0051325	interphase	4.496093e-5
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	4.772906e-5
GO:0009159	deoxyribonucleoside monophosphate catabolic process	4.784100e-5
GO:0016598	protein arginylation	4.784100e-5
GO:0021854	hypothalamus development	4.973412e-5
GO:0060839	endothelial cell fate commitment	5.015595e-5
GO:0009956	radial pattern formation	5.074748e-5
GO:0034508	centromere complex assembly	5.688145e-5
GO:0006406	mRNA export from nucleus	5.890852e-5
GO:0009108	coenzyme biosynthetic process	6.073549e-5
GO:0000725	recombinational repair	6.217175e-5
GO:0030198	extracellular matrix organization	6.715626e-5
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	7.325839e-5
GO:0060350	endochondral bone morphogenesis	7.569724e-5
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	7.693908e-5
GO:0006974	response to DNA damage stimulus	8.199173e-5
GO:0046907	intracellular transport	8.397453e-5
GO:0000724	double-strand break repair via homologous recombination	8.470975e-5
GO:0006586	indolalkylamine metabolic process	8.818017e-5
GO:0006096	glycolysis	8.907030e-5
GO:0002063	chondrocyte development	9.085484e-5
GO:0032964	collagen biosynthetic process	9.879806e-5
GO:0042538	hyperosmotic salinity response	9.974227e-5
GO:0021759	globus pallidus development	1.026435e-4
GO:0051188	cofactor biosynthetic process	1.125420e-4
GO:0010966	regulation of phosphate transport	1.182738e-4
GO:0042402	cellular biogenic amine catabolic process	1.219321e-4
GO:0001894	tissue homeostasis	1.294911e-4
GO:0051329	interphase of mitotic cell cycle	1.315800e-4
GO:0035308	negative regulation of protein dephosphorylation	1.372494e-4
GO:0009072	aromatic amino acid family metabolic process	1.414542e-4
GO:0044236	multicellular organismal metabolic process	1.486423e-4
GO:0035305	negative regulation of dephosphorylation	1.504373e-4
GO:0006744	ubiquinone biosynthetic process	1.623602e-4
GO:0042696	menarche	1.695106e-4
GO:0031497	chromatin assembly	1.744789e-4
GO:0050908	detection of light stimulus involved in visual perception	1.782770e-4
GO:0000075	cell cycle checkpoint	1.844882e-4
GO:0034442	regulation of lipoprotein oxidation	1.906090e-4
GO:0010948	negative regulation of cell cycle process	1.959826e-4
GO:0070925	organelle assembly	2.028665e-4
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway	2.186248e-4
GO:0032298	positive regulation of DNA-dependent DNA replication initiation	2.237762e-4
GO:0030683	evasion by virus of host immune response	2.237762e-4
GO:0006272	leading strand elongation	2.237762e-4
GO:0007093	mitotic cell cycle checkpoint	2.251097e-4
GO:0033693	neurofilament bundle assembly	2.338011e-4
GO:0009303	rRNA transcription	2.358436e-4
GO:0015931	nucleobase-containing compound transport	2.490998e-4
GO:0006171	cAMP biosynthetic process	2.502033e-4
GO:0048339	paraxial mesoderm development	2.516006e-4
GO:0045426	quinone cofactor biosynthetic process	2.528446e-4
GO:0022601	menstrual cycle phase	2.586263e-4
GO:0030388	fructose 1,6-bisphosphate metabolic process	2.642746e-4
GO:0006418	tRNA aminoacylation for protein translation	2.662188e-4
GO:0043039	tRNA aminoacylation	2.726617e-4
GO:0035089	establishment of apical/basal cell polarity	2.796022e-4
GO:0006768	biotin metabolic process	2.802783e-4
GO:0009107	lipoate biosynthetic process	2.869931e-4
GO:0050690	regulation of defense response to virus by virus	2.959515e-4
GO:0030199	collagen fibril organization	3.002309e-4
GO:0071824	protein-DNA complex subunit organization	3.016529e-4
GO:0035545	determination of left/right asymmetry in nervous system	3.033965e-4
GO:0031124	mRNA 3'-end processing	3.066321e-4
GO:0051004	regulation of lipoprotein lipase activity	3.144278e-4
GO:0043503	skeletal muscle fiber adaptation	3.204724e-4
GO:0044205	'de novo' UMP biosynthetic process	3.226370e-4
GO:0006334	nucleosome assembly	3.539524e-4
GO:0042661	regulation of mesodermal cell fate specification	3.547005e-4
GO:0045116	protein neddylation	3.612208e-4
GO:0006405	RNA export from nucleus	3.699914e-4
GO:0060850	regulation of transcription involved in cell fate commitment	3.828816e-4
GO:0031060	regulation of histone methylation	3.932715e-4
GO:0015758	glucose transport	4.010256e-4
GO:0034509	centromeric core chromatin assembly	4.133684e-4
GO:0042375	quinone cofactor metabolic process	4.279791e-4
GO:0006310	DNA recombination	4.492907e-4
GO:0042770	signal transduction in response to DNA damage	4.543370e-4
GO:0007215	glutamate signaling pathway	4.559691e-4
GO:0019363	pyridine nucleotide biosynthetic process	4.654452e-4
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	4.663752e-4
GO:0002897	positive regulation of central B cell tolerance induction	4.737669e-4
GO:0002508	central tolerance induction	4.737669e-4
GO:0070375	BMK cascade	4.737877e-4
GO:0008645	hexose transport	4.909314e-4
GO:0051930	regulation of sensory perception of pain	4.949437e-4
GO:0021520	spinal cord motor neuron cell fate specification	5.298053e-4
GO:0015749	monosaccharide transport	5.424070e-4
GO:0032637	interleukin-8 production	5.550652e-4
GO:0022403	cell cycle phase	5.671566e-4
GO:0019511	peptidyl-proline hydroxylation	5.726575e-4
GO:0071156	regulation of cell cycle arrest	5.728675e-4
GO:2000380	regulation of mesoderm development	5.822434e-4
GO:0006323	DNA packaging	5.911451e-4
GO:0043691	reverse cholesterol transport	5.959113e-4
GO:0051017	actin filament bundle assembly	6.015652e-4
GO:0010596	negative regulation of endothelial cell migration	6.023926e-4
GO:0032463	negative regulation of protein homooligomerization	6.094073e-4
GO:0000086	G2/M transition of mitotic cell cycle	6.221630e-4
GO:0051788	response to misfolded protein	6.230307e-4
GO:2000779	regulation of double-strand break repair	6.242136e-4
GO:0060836	lymphatic endothelial cell differentiation	6.356608e-4
GO:0019805	quinolinate biosynthetic process	6.372090e-4
GO:0001831	trophectodermal cellular morphogenesis	6.462738e-4
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	6.567541e-4
GO:2000143	negative regulation of transcription initiation, DNA-dependent	6.641455e-4
GO:2000627	positive regulation of miRNA catabolic process	6.641455e-4
GO:0071042	nuclear polyadenylation-dependent mRNA catabolic process	6.641455e-4
GO:0000964	mitochondrial RNA 5'-end processing	6.641455e-4
GO:0000416	positive regulation of histone H3-K36 methylation	6.641455e-4
GO:0032963	collagen metabolic process	6.741872e-4
GO:0007029	endoplasmic reticulum organization	6.801966e-4
GO:0007017	microtubule-based process	6.853250e-4
GO:0061157	mRNA destabilization	7.102910e-4
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	7.102910e-4
GO:0046874	quinolinate metabolic process	7.488774e-4
GO:0044259	multicellular organismal macromolecule metabolic process	7.496770e-4
GO:0051177	meiotic sister chromatid cohesion	7.577918e-4
GO:0009304	tRNA transcription	7.633050e-4
GO:0051382	kinetochore assembly	7.685412e-4
GO:0006769	nicotinamide metabolic process	8.356790e-4
GO:0007530	sex determination	8.786920e-4
GO:0000413	protein peptidyl-prolyl isomerization	8.819155e-4
GO:0021771	lateral geniculate nucleus development	8.966864e-4
GO:0034377	plasma lipoprotein particle assembly	9.464510e-4
GO:0034728	nucleosome organization	9.595459e-4
GO:0060351	cartilage development involved in endochondral bone morphogenesis	9.637031e-4
GO:0043603	cellular amide metabolic process	1.014971e-3
GO:0061011	hepatic duct development	1.028705e-3
GO:0021586	pons maturation	1.028705e-3
GO:0072148	epithelial cell fate commitment	1.048755e-3
GO:0042048	olfactory behavior	1.071244e-3
GO:0051893	regulation of focal adhesion assembly	1.108487e-3
GO:0021877	forebrain neuron fate commitment	1.195687e-3
GO:0042274	ribosomal small subunit biogenesis	1.222589e-3
GO:0070972	protein localization in endoplasmic reticulum	1.252727e-3
GO:0070727	cellular macromolecule localization	1.265523e-3
GO:0060249	anatomical structure homeostasis	1.265988e-3
GO:0019047	provirus integration	1.267560e-3
GO:0031398	positive regulation of protein ubiquitination	1.271580e-3
GO:0009584	detection of visible light	1.276810e-3
GO:0042534	regulation of tumor necrosis factor biosynthetic process	1.282264e-3
GO:0006000	fructose metabolic process	1.331726e-3
GO:0018027	peptidyl-lysine dimethylation	1.348559e-3
GO:0015031	protein transport	1.376175e-3
GO:0009435	NAD biosynthetic process	1.386763e-3
GO:0051383	kinetochore organization	1.388297e-3
GO:0045786	negative regulation of cell cycle	1.407431e-3
GO:0000414	regulation of histone H3-K36 methylation	1.454910e-3
GO:0051649	establishment of localization in cell	1.479501e-3
GO:0009642	response to light intensity	1.483620e-3
GO:0000090	mitotic anaphase	1.485093e-3
GO:0060059	embryonic retina morphogenesis in camera-type eye	1.498325e-3
GO:0043049	otic placode formation	1.528226e-3
GO:0022417	protein maturation by protein folding	1.595492e-3
GO:0001880	Mullerian duct regression	1.617972e-3
GO:0045184	establishment of protein localization	1.622285e-3
GO:0071827	plasma lipoprotein particle organization	1.656777e-3
GO:0060033	anatomical structure regression	1.657106e-3
GO:0007173	epidermal growth factor receptor signaling pathway	1.657783e-3
GO:0042254	ribosome biogenesis	1.666851e-3
GO:0006710	androgen catabolic process	1.687376e-3
GO:0060897	neural plate regionalization	1.700159e-3
GO:0031123	RNA 3'-end processing	1.729375e-3
GO:0021872	forebrain generation of neurons	1.757082e-3
GO:0048664	neuron fate determination	1.769028e-3
GO:0031627	telomeric loop formation	1.773988e-3
GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.773988e-3
GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.773988e-3
GO:0034613	cellular protein localization	1.816807e-3
GO:0010812	negative regulation of cell-substrate adhesion	1.819171e-3
GO:2000124	regulation of endocannabinoid signaling pathway	1.827633e-3
GO:0033007	negative regulation of mast cell activation involved in immune response	1.830910e-3
GO:0014829	vascular smooth muscle contraction	1.831781e-3
GO:0033632	regulation of cell-cell adhesion mediated by integrin	1.847975e-3
GO:0006260	DNA replication	1.866473e-3
GO:0003203	endocardial cushion morphogenesis	1.897608e-3
GO:0032467	positive regulation of cytokinesis	1.897608e-3
GO:0006007	glucose catabolic process	1.942484e-3
GO:0032241	positive regulation of nucleobase-containing compound transport	1.981217e-3
GO:0070192	chromosome organization involved in meiosis	2.036657e-3
GO:0035304	regulation of protein dephosphorylation	2.044330e-3
GO:0030916	otic vesicle formation	2.084522e-3
GO:0002092	positive regulation of receptor internalization	2.086943e-3
GO:0001937	negative regulation of endothelial cell proliferation	2.090152e-3
GO:0008054	cyclin catabolic process	2.145928e-3
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	2.182997e-3
GO:0035694	mitochondrial protein catabolic process	2.306349e-3
GO:0032515	negative regulation of phosphoprotein phosphatase activity	2.321444e-3
GO:0072334	UDP-galactose transmembrane transport	2.358459e-3
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	2.358459e-3
GO:0061032	visceral serous pericardium development	2.358459e-3
GO:0035137	hindlimb morphogenesis	2.427449e-3
GO:0007224	smoothened signaling pathway	2.431220e-3
GO:0000730	DNA recombinase assembly	2.522209e-3
GO:0001787	natural killer cell proliferation	2.590983e-3
GO:0060044	negative regulation of cardiac muscle cell proliferation	2.640268e-3
GO:0051225	spindle assembly	2.642402e-3
GO:0021837	motogenic signaling involved in postnatal olfactory bulb interneuron migration	2.653238e-3
GO:0008355	olfactory learning	2.653238e-3
GO:0019359	nicotinamide nucleotide biosynthetic process	2.653328e-3
GO:0030865	cortical cytoskeleton organization	2.756938e-3
GO:0071103	DNA conformation change	2.816406e-3
GO:0007194	negative regulation of adenylate cyclase activity	2.833275e-3
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	2.837158e-3
GO:0048702	embryonic neurocranium morphogenesis	2.837158e-3
GO:0043310	negative regulation of eosinophil degranulation	2.858256e-3
GO:2000409	positive regulation of T cell extravasation	2.858256e-3
GO:0051106	positive regulation of DNA ligation	2.858256e-3
GO:0035705	T-helper 17 cell chemotaxis	2.858256e-3
GO:0035696	monocyte extravasation	2.858256e-3
GO:0015891	siderophore transport	2.909718e-3
GO:0071850	mitotic cell cycle arrest	2.911456e-3
GO:0060123	regulation of growth hormone secretion	2.912782e-3
GO:0051532	regulation of NFAT protein import into nucleus	2.933920e-3
GO:0000216	M/G1 transition of mitotic cell cycle	2.940549e-3
GO:0006342	chromatin silencing	2.983344e-3
GO:0006959	humoral immune response	3.006060e-3
GO:0008629	induction of apoptosis by intracellular signals	3.022479e-3
GO:0042026	protein refolding	3.042244e-3
GO:0048668	collateral sprouting	3.182120e-3
GO:0051641	cellular localization	3.215151e-3
GO:0009190	cyclic nucleotide biosynthetic process	3.259257e-3
GO:0012502	induction of programmed cell death	3.267962e-3
GO:0043633	polyadenylation-dependent RNA catabolic process	3.286429e-3
GO:0000965	mitochondrial RNA 3'-end processing	3.286429e-3
GO:0000962	positive regulation of mitochondrial RNA catabolic process	3.286429e-3
GO:0000958	mitochondrial mRNA catabolic process	3.286429e-3
GO:0051208	sequestering of calcium ion	3.364240e-3
GO:0061072	iris morphogenesis	3.411062e-3
GO:0006766	vitamin metabolic process	3.412811e-3
GO:0002380	immunoglobulin secretion involved in immune response	3.482537e-3
GO:0002635	negative regulation of germinal center formation	3.482537e-3
GO:0051350	negative regulation of lyase activity	3.491889e-3
GO:0090129	positive regulation of synapse maturation	3.535529e-3
GO:0008089	anterograde axon cargo transport	3.535529e-3
GO:0003272	endocardial cushion formation	3.535529e-3
GO:0006911	phagocytosis, engulfment	3.628998e-3
GO:0090174	organelle membrane fusion	3.722484e-3
GO:0015684	ferrous iron transport	3.722484e-3
GO:0009162	deoxyribonucleoside monophosphate metabolic process	3.722484e-3
GO:0045740	positive regulation of DNA replication	3.736657e-3
GO:0007088	regulation of mitosis	3.745981e-3
GO:0071896	protein localization to adherens junction	3.861522e-3
GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine	3.861522e-3
GO:0008104	protein localization	3.863086e-3
GO:0015780	nucleotide-sugar transport	3.884492e-3
GO:0060486	Clara cell differentiation	3.897926e-3
GO:0048263	determination of dorsal identity	3.949184e-3
GO:0022002	negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway	3.949184e-3
GO:0034622	cellular macromolecular complex assembly	3.997809e-3
GO:0051563	smooth endoplasmic reticulum calcium ion homeostasis	4.000306e-3
GO:0006917	induction of apoptosis	4.001692e-3
GO:0033081	regulation of T cell differentiation in thymus	4.148208e-3
GO:0032854	positive regulation of Rap GTPase activity	4.173134e-3
GO:0001935	endothelial cell proliferation	4.177960e-3
GO:0042921	glucocorticoid receptor signaling pathway	4.260722e-3
GO:0007130	synaptonemal complex assembly	4.261305e-3
GO:0042074	cell migration involved in gastrulation	4.290938e-3
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	4.335910e-3
GO:0018026	peptidyl-lysine monomethylation	4.367898e-3
GO:0015918	sterol transport	4.480098e-3
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis	4.535345e-3
GO:0030330	DNA damage response, signal transduction by p53 class mediator	4.583760e-3
GO:0006477	protein sulfation	4.623183e-3
GO:0031279	regulation of cyclase activity	4.838216e-3
GO:0034379	very-low-density lipoprotein particle assembly	4.934622e-3
GO:0043149	stress fiber assembly	5.313590e-3
GO:0007126	meiosis	5.315264e-3
GO:0044070	regulation of anion transport	5.319867e-3
GO:0032594	protein transport within lipid bilayer	5.400464e-3
GO:0007283	spermatogenesis	5.437838e-3
GO:0071777	positive regulation of cell cycle cytokinesis	5.513988e-3
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	5.538586e-3
GO:0009794	regulation of mitotic cell cycle, embryonic	5.549503e-3
GO:0010608	posttranscriptional regulation of gene expression	5.675270e-3
GO:0040040	thermosensory behavior	5.712577e-3
GO:0070059	apoptosis in response to endoplasmic reticulum stress	5.753969e-3
GO:0016072	rRNA metabolic process	5.843403e-3
GO:0031062	positive regulation of histone methylation	5.869371e-3
GO:0019882	antigen processing and presentation	5.899619e-3
GO:0006733	oxidoreduction coenzyme metabolic process	5.993240e-3
GO:0030301	cholesterol transport	6.012407e-3
GO:0009886	post-embryonic morphogenesis	6.059891e-3
GO:0090128	regulation of synapse maturation	6.080246e-3
GO:0006353	transcription termination, DNA-dependent	6.141797e-3
GO:0001921	positive regulation of receptor recycling	6.172874e-3
GO:0072132	mesenchyme morphogenesis	6.176287e-3
GO:0070734	histone H3-K27 methylation	6.205932e-3
GO:0008334	histone mRNA metabolic process	6.263187e-3
GO:0035150	regulation of tube size	6.308329e-3
GO:0072331	signal transduction by p53 class mediator	6.375847e-3
GO:0051443	positive regulation of ubiquitin-protein ligase activity	6.398231e-3
GO:0034470	ncRNA processing	6.487768e-3
GO:0006892	post-Golgi vesicle-mediated transport	6.512258e-3
GO:0031128	developmental induction	6.568797e-3
GO:0019320	hexose catabolic process	6.607509e-3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	6.610997e-3
GO:0045609	positive regulation of auditory receptor cell differentiation	6.632970e-3
GO:0043622	cortical microtubule organization	6.632970e-3
GO:0046833	positive regulation of RNA export from nucleus	6.632970e-3
GO:0030103	vasopressin secretion	6.632970e-3
GO:0042270	protection from natural killer cell mediated cytotoxicity	6.632970e-3
GO:0042667	auditory receptor cell fate specification	6.632970e-3
GO:0046365	monosaccharide catabolic process	6.643434e-3
GO:0007160	cell-matrix adhesion	6.678488e-3
GO:0071844	cellular component assembly at cellular level	6.720475e-3
GO:0035235	ionotropic glutamate receptor signaling pathway	6.733373e-3
GO:0018874	benzoate metabolic process	6.742678e-3
GO:0010950	positive regulation of endopeptidase activity	6.742678e-3
GO:0061017	hepatoblast differentiation	6.793089e-3
GO:0051571	positive regulation of histone H3-K4 methylation	6.835116e-3
GO:0001919	regulation of receptor recycling	6.896273e-3
GO:0046079	dUMP catabolic process	6.962720e-3
GO:0030225	macrophage differentiation	6.979098e-3
GO:0001958	endochondral ossification	7.042003e-3
GO:0031061	negative regulation of histone methylation	7.084431e-3
GO:0051322	anaphase	7.094648e-3
GO:0003420	regulation of growth plate cartilage chondrocyte proliferation	7.123465e-3
GO:0007602	phototransduction	7.135576e-3
GO:0006399	tRNA metabolic process	7.197596e-3
GO:0071157	negative regulation of cell cycle arrest	7.201271e-3
GO:0003197	endocardial cushion development	7.406351e-3
GO:0050880	regulation of blood vessel size	7.406558e-3
GO:0061136	regulation of proteasomal protein catabolic process	7.464476e-3
GO:0045761	regulation of adenylate cyclase activity	7.492930e-3
GO:0043497	regulation of protein heterodimerization activity	7.534760e-3
GO:0007097	nuclear migration	7.534760e-3
GO:0042476	odontogenesis	7.551778e-3
GO:0033036	macromolecule localization	7.660396e-3
GO:0000085	G2 phase of mitotic cell cycle	7.862821e-3
GO:0021521	ventral spinal cord interneuron specification	7.932275e-3
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	8.008724e-3
GO:0002541	activation of plasma proteins involved in acute inflammatory response	8.145835e-3
GO:0006268	DNA unwinding involved in replication	8.276555e-3
GO:0015986	ATP synthesis coupled proton transport	8.382823e-3
GO:0043525	positive regulation of neuron apoptosis	8.385775e-3
GO:0006269	DNA replication, synthesis of RNA primer	8.427865e-3
GO:0006913	nucleocytoplasmic transport	8.443421e-3
GO:0030502	negative regulation of bone mineralization	8.547113e-3
GO:0019896	axon transport of mitochondrion	8.591366e-3
GO:0051321	meiotic cell cycle	8.649812e-3
GO:0034621	cellular macromolecular complex subunit organization	8.749673e-3
GO:0031444	slow-twitch skeletal muscle fiber contraction	8.890794e-3
GO:0051983	regulation of chromosome segregation	9.149305e-3
GO:0021879	forebrain neuron differentiation	9.184921e-3
GO:0046210	nitric oxide catabolic process	9.368025e-3
GO:0090346	cellular organofluorine metabolic process	9.368025e-3
GO:0043602	nitrate catabolic process	9.368025e-3
GO:0042228	interleukin-8 biosynthetic process	9.368025e-3
GO:0001575	globoside metabolic process	9.368025e-3
GO:0035752	lysosomal lumen pH elevation	9.368025e-3
GO:0000046	autophagic vacuole fusion	9.368025e-3
GO:0022402	cell cycle process	9.465703e-3
GO:0060431	primary lung bud formation	9.466979e-3
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	9.526124e-3
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	9.557702e-3
GO:0051029	rRNA transport	9.765408e-3
GO:0021800	cerebral cortex tangential migration	9.765408e-3
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	9.898570e-3
GO:0097114	N-methyl-D-aspartate receptor clustering	1.004216e-2
GO:0097117	guanylate kinase-associated protein clustering	1.004216e-2
GO:0097112	gamma-aminobutyric acid receptor clustering	1.004216e-2
GO:0045110	intermediate filament bundle assembly	1.007210e-2
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.010105e-2
GO:0051895	negative regulation of focal adhesion assembly	1.012896e-2
GO:0006270	DNA-dependent DNA replication initiation	1.015598e-2
GO:0008298	intracellular mRNA localization	1.022474e-2
GO:0030866	cortical actin cytoskeleton organization	1.039374e-2
GO:0010043	response to zinc ion	1.047798e-2
GO:0045047	protein targeting to ER	1.051935e-2
GO:0070979	protein K11-linked ubiquitination	1.054446e-2
GO:0045040	protein import into mitochondrial outer membrane	1.068765e-2
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	1.072164e-2
GO:0007402	ganglion mother cell fate determination	1.072164e-2
GO:0006428	isoleucyl-tRNA aminoacylation	1.072164e-2
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	1.072164e-2
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	1.080060e-2
GO:0051169	nuclear transport	1.094165e-2
GO:0051339	regulation of lyase activity	1.094724e-2
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	1.100430e-2
GO:0042335	cuticle development	1.100430e-2
GO:0007141	male meiosis I	1.112820e-2
GO:0022415	viral reproductive process	1.116032e-2
GO:0006333	chromatin assembly or disassembly	1.128294e-2
GO:0006829	zinc ion transport	1.131997e-2
GO:0035928	rRNA import into mitochondrion	1.135058e-2
GO:0009106	lipoate metabolic process	1.142986e-2
GO:0048855	adenohypophysis morphogenesis	1.151224e-2
GO:0021933	radial glia guided migration of cerebellar granule cell	1.151224e-2
GO:0045070	positive regulation of viral genome replication	1.156354e-2
GO:0045650	negative regulation of macrophage differentiation	1.180430e-2
GO:0009620	response to fungus	1.192995e-2
GO:0070168	negative regulation of biomineral tissue development	1.200362e-2
GO:0035306	positive regulation of dephosphorylation	1.200362e-2
GO:0022617	extracellular matrix disassembly	1.209303e-2
GO:0046785	microtubule polymerization	1.215735e-2
GO:0030174	regulation of DNA-dependent DNA replication initiation	1.226705e-2
GO:0014826	vein smooth muscle contraction	1.247814e-2
GO:0035095	behavioral response to nicotine	1.252828e-2
GO:0048368	lateral mesoderm development	1.252831e-2
GO:0048669	collateral sprouting in absence of injury	1.273026e-2
GO:0060965	negative regulation of gene silencing by miRNA	1.274315e-2
GO:0046690	response to tellurium ion	1.274315e-2
GO:0009645	response to low light intensity stimulus	1.274315e-2
GO:0060684	epithelial-mesenchymal cell signaling	1.285902e-2
GO:0007192	activation of adenylate cyclase activity by serotonin receptor signaling pathway	1.293317e-2
GO:0060370	susceptibility to T cell mediated cytotoxicity	1.293317e-2
GO:0010923	negative regulation of phosphatase activity	1.319911e-2
GO:0031958	corticosteroid receptor signaling pathway	1.320780e-2
GO:0032695	negative regulation of interleukin-12 production	1.352737e-2
GO:0045793	positive regulation of cell size	1.353475e-2
GO:0006886	intracellular protein transport	1.359000e-2
GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter	1.378798e-2
GO:0010896	regulation of triglyceride catabolic process	1.379724e-2
GO:0019264	glycine biosynthetic process from serine	1.387835e-2
GO:0000921	septin ring assembly	1.387835e-2
GO:0051569	regulation of histone H3-K4 methylation	1.396566e-2
GO:0030032	lamellipodium assembly	1.408566e-2
GO:0045994	positive regulation of translational initiation by iron	1.411368e-2
GO:0002037	negative regulation of L-glutamate transport	1.411368e-2
GO:0048871	multicellular organismal homeostasis	1.416752e-2
GO:0007598	blood coagulation, extrinsic pathway	1.421754e-2
GO:0018199	peptidyl-glutamine modification	1.428320e-2
GO:0045930	negative regulation of mitotic cell cycle	1.428710e-2
GO:0006364	rRNA processing	1.451149e-2
GO:0007131	reciprocal meiotic recombination	1.452198e-2
GO:0072393	microtubule anchoring at microtubule organizing center	1.456084e-2
GO:0034380	high-density lipoprotein particle assembly	1.471386e-2
GO:0060923	cardiac muscle cell fate commitment	1.491892e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0031442	positive regulation of mRNA 3'-end processing	1.944008e-9
GO:0006654	phosphatidic acid biosynthetic process	2.090752e-9
GO:0035621	ER to Golgi ceramide transport	2.150638e-9
GO:0009956	radial pattern formation	8.038317e-9
GO:0031440	regulation of mRNA 3'-end processing	2.562792e-8
GO:0045109	intermediate filament organization	2.792217e-8
GO:0045730	respiratory burst	3.313580e-8
GO:0060850	regulation of transcription involved in cell fate commitment	1.330505e-7
GO:0006297	nucleotide-excision repair, DNA gap filling	1.636296e-7
GO:0006119	oxidative phosphorylation	1.813740e-7
GO:0006650	glycerophospholipid metabolic process	4.850524e-7
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	5.306919e-7
GO:0061014	positive regulation of mRNA catabolic process	5.390062e-7
GO:0060839	endothelial cell fate commitment	8.335528e-7
GO:0060836	lymphatic endothelial cell differentiation	1.037666e-6
GO:0050685	positive regulation of mRNA processing	1.125610e-6
GO:0045087	innate immune response	1.247636e-6
GO:0031133	regulation of axon diameter	1.270602e-6
GO:0050832	defense response to fungus	1.492787e-6
GO:0051788	response to misfolded protein	1.865320e-6
GO:0046488	phosphatidylinositol metabolic process	1.940180e-6
GO:0032049	cardiolipin biosynthetic process	2.322705e-6
GO:0045128	negative regulation of reciprocal meiotic recombination	2.449178e-6
GO:0006311	meiotic gene conversion	2.449178e-6
GO:0018293	protein-FAD linkage	3.110542e-6
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	3.110542e-6
GO:0032536	regulation of cell projection size	4.552956e-6
GO:0006515	misfolded or incompletely synthesized protein catabolic process	5.384841e-6
GO:0045104	intermediate filament cytoskeleton organization	5.598855e-6
GO:0071712	ER-associated misfolded protein catabolic process	5.971670e-6
GO:0030521	androgen receptor signaling pathway	7.140347e-6
GO:0051095	regulation of helicase activity	7.147172e-6
GO:0002827	positive regulation of T-helper 1 type immune response	8.683326e-6
GO:0042743	hydrogen peroxide metabolic process	9.439169e-6
GO:0071218	cellular response to misfolded protein	9.965379e-6
GO:0032048	cardiolipin metabolic process	9.965379e-6
GO:0045103	intermediate filament-based process	1.082740e-5
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.105457e-5
GO:0032094	response to food	1.177682e-5
GO:0045650	negative regulation of macrophage differentiation	1.225245e-5
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	1.225245e-5
GO:0006801	superoxide metabolic process	1.292069e-5
GO:0051096	positive regulation of helicase activity	1.347522e-5
GO:0060215	primitive hemopoiesis	1.779082e-5
GO:0034227	tRNA thio-modification	1.800085e-5
GO:0042035	regulation of cytokine biosynthetic process	2.040947e-5
GO:0046854	phosphatidylinositol phosphorylation	2.119014e-5
GO:0050748	negative regulation of lipoprotein metabolic process	2.235762e-5
GO:0002149	hypochlorous acid biosynthetic process	2.334594e-5
GO:0003158	endothelium development	2.873171e-5
GO:0043154	negative regulation of caspase activity	3.040438e-5
GO:0006982	response to lipid hydroperoxide	4.103634e-5
GO:0006370	mRNA capping	4.451218e-5
GO:0032922	circadian regulation of gene expression	4.662743e-5
GO:0006301	postreplication repair	5.474106e-5
GO:0042775	mitochondrial ATP synthesis coupled electron transport	5.616309e-5
GO:0072148	epithelial cell fate commitment	6.028651e-5
GO:0021892	cerebral cortex GABAergic interneuron differentiation	6.028651e-5
GO:0046834	lipid phosphorylation	6.066499e-5
GO:0006644	phospholipid metabolic process	6.113071e-5
GO:0021877	forebrain neuron fate commitment	6.625278e-5
GO:0019430	removal of superoxide radicals	7.139719e-5
GO:0009125	nucleoside monophosphate catabolic process	7.497393e-5
GO:0015802	basic amino acid transport	7.998986e-5
GO:0018192	enzyme active site formation via L-cysteine persulfide	8.001682e-5
GO:0070253	somatostatin secretion	8.303264e-5
GO:0032812	positive regulation of epinephrine secretion	8.303264e-5
GO:0042773	ATP synthesis coupled electron transport	8.390672e-5
GO:0002098	tRNA wobble uridine modification	8.490533e-5
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	8.517331e-5
GO:0002227	innate immune response in mucosa	8.908249e-5
GO:0000303	response to superoxide	9.255491e-5
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	9.374871e-5
GO:0009620	response to fungus	9.465384e-5
GO:0042538	hyperosmotic salinity response	9.573590e-5
GO:0000710	meiotic mismatch repair	9.872798e-5
GO:0061013	regulation of mRNA catabolic process	1.033379e-4
GO:0042744	hydrogen peroxide catabolic process	1.167863e-4
GO:0045686	negative regulation of glial cell differentiation	1.173480e-4
GO:0060631	regulation of meiosis I	1.216238e-4
GO:0032057	negative regulation of translational initiation in response to stress	1.396634e-4
GO:0030258	lipid modification	1.491187e-4
GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process	1.651483e-4
GO:0010898	positive regulation of triglyceride catabolic process	1.671434e-4
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	1.758645e-4
GO:0002679	respiratory burst involved in defense response	1.828177e-4
GO:0010520	regulation of reciprocal meiotic recombination	1.853777e-4
GO:0045076	regulation of interleukin-2 biosynthetic process	1.898488e-4
GO:0060029	convergent extension involved in organogenesis	1.908893e-4
GO:0048715	negative regulation of oligodendrocyte differentiation	1.981877e-4
GO:0002825	regulation of T-helper 1 type immune response	2.022672e-4
GO:0055090	acylglycerol homeostasis	2.045495e-4
GO:0046092	deoxycytidine metabolic process	2.094611e-4
GO:0032055	negative regulation of translation in response to stress	2.139117e-4
GO:0001887	selenium compound metabolic process	2.139117e-4
GO:0030224	monocyte differentiation	2.171962e-4
GO:0045835	negative regulation of meiosis	2.243818e-4
GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste	2.243818e-4
GO:0022617	extracellular matrix disassembly	2.243818e-4
GO:0014014	negative regulation of gliogenesis	2.284010e-4
GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity	2.297297e-4
GO:0060377	negative regulation of mast cell differentiation	2.297297e-4
GO:0002821	positive regulation of adaptive immune response	2.364865e-4
GO:0050913	sensory perception of bitter taste	2.443201e-4
GO:0008340	determination of adult lifespan	2.502885e-4
GO:0046426	negative regulation of JAK-STAT cascade	2.623814e-4
GO:0001573	ganglioside metabolic process	2.842881e-4
GO:0003139	secondary heart field specification	2.895686e-4
GO:0030321	transepithelial chloride transport	2.913554e-4
GO:0001878	response to yeast	2.927257e-4
GO:0046474	glycerophospholipid biosynthetic process	2.958978e-4
GO:2000178	negative regulation of neural precursor cell proliferation	3.261296e-4
GO:0035674	tricarboxylic acid transmembrane transport	3.311353e-4
GO:0071352	cellular response to interleukin-2	3.355176e-4
GO:0002561	basophil degranulation	3.355176e-4
GO:0032077	positive regulation of deoxyribonuclease activity	3.549907e-4
GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.549907e-4
GO:0000305	response to oxygen radical	3.976624e-4
GO:0006777	Mo-molybdopterin cofactor biosynthetic process	4.039857e-4
GO:0006659	phosphatidylserine biosynthetic process	4.055382e-4
GO:0045649	regulation of macrophage differentiation	4.055382e-4
GO:0048389	intermediate mesoderm development	4.115251e-4
GO:0072098	anterior/posterior pattern specification involved in kidney development	4.115251e-4
GO:0042732	D-xylose metabolic process	4.115251e-4
GO:0032425	positive regulation of mismatch repair	4.115251e-4
GO:0009452	RNA capping	4.327503e-4
GO:0009214	cyclic nucleotide catabolic process	4.398269e-4
GO:0031295	T cell costimulation	4.459906e-4
GO:0051100	negative regulation of binding	4.468439e-4
GO:0048609	multicellular organismal reproductive process	4.532551e-4
GO:0022007	convergent extension involved in neural plate elongation	4.584987e-4
GO:0046641	positive regulation of alpha-beta T cell proliferation	4.732270e-4
GO:0010596	negative regulation of endothelial cell migration	4.784291e-4
GO:0001945	lymph vessel development	4.804362e-4
GO:0045723	positive regulation of fatty acid biosynthetic process	4.807630e-4
GO:0010954	positive regulation of protein processing	5.166278e-4
GO:0060152	microtubule-based peroxisome localization	5.405335e-4
GO:0005997	xylulose metabolic process	5.413787e-4
GO:0045078	positive regulation of interferon-gamma biosynthetic process	5.430290e-4
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	5.570724e-4
GO:0045662	negative regulation of myoblast differentiation	5.605131e-4
GO:0000003	reproduction	5.710044e-4
GO:0070093	negative regulation of glucagon secretion	5.716039e-4
GO:0033566	gamma-tubulin complex localization	5.716039e-4
GO:0019637	organophosphate metabolic process	5.750509e-4
GO:0060052	neurofilament cytoskeleton organization	5.758546e-4
GO:0002922	positive regulation of humoral immune response	6.038128e-4
GO:0045446	endothelial cell differentiation	6.094842e-4
GO:0019953	sexual reproduction	6.104647e-4
GO:0046486	glycerolipid metabolic process	6.180756e-4
GO:0021761	limbic system development	6.409744e-4
GO:0019985	translesion synthesis	6.492093e-4
GO:0032849	positive regulation of cellular pH reduction	6.902568e-4
GO:0006405	RNA export from nucleus	7.078953e-4
GO:0014060	regulation of epinephrine secretion	7.234231e-4
GO:0045575	basophil activation	7.387660e-4
GO:0060632	regulation of microtubule-based movement	7.538545e-4
GO:0042129	regulation of T cell proliferation	7.654024e-4
GO:0045409	negative regulation of interleukin-6 biosynthetic process	7.667012e-4
GO:0001967	suckling behavior	7.707477e-4
GO:0042108	positive regulation of cytokine biosynthetic process	7.839390e-4
GO:0072200	negative regulation of mesenchymal cell proliferation involved in ureter development	7.866424e-4
GO:0072198	mesenchymal cell proliferation involved in ureter development	7.866424e-4
GO:0072138	mesenchymal cell proliferation involved in ureteric bud development	7.866424e-4
GO:0072101	specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway	7.866424e-4
GO:0072192	ureter epithelial cell differentiation	7.866424e-4
GO:2000137	negative regulation of cell proliferation involved in heart morphogenesis	7.866424e-4
GO:2000007	negative regulation of metanephric comma-shaped body morphogenesis	7.866424e-4
GO:2000005	negative regulation of metanephric S-shaped body morphogenesis	7.866424e-4
GO:0090194	negative regulation of glomerulus development	7.866424e-4
GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis	7.866424e-4
GO:0060503	bud dilation involved in lung branching	7.866424e-4
GO:0055020	positive regulation of cardiac muscle fiber development	7.866424e-4
GO:0048392	intermediate mesodermal cell differentiation	7.866424e-4
GO:0035269	protein O-linked mannosylation	7.866424e-4
GO:0007500	mesodermal cell fate determination	7.866424e-4
GO:0072097	negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway	7.866424e-4
GO:0060502	epithelial cell proliferation involved in lung morphogenesis	7.866424e-4
GO:0071893	BMP signaling pathway involved in nephric duct formation	7.866424e-4
GO:0061149	BMP signaling pathway involved in ureter morphogenesis	7.866424e-4
GO:0061155	pulmonary artery endothelial tube morphogenesis	7.866424e-4
GO:0061151	BMP signaling pathway involved in renal system segmentation	7.866424e-4
GO:0034104	negative regulation of tissue remodeling	7.875861e-4
GO:0010613	positive regulation of cardiac muscle hypertrophy	7.875861e-4
GO:0032202	telomere assembly	7.923566e-4
GO:0016560	protein import into peroxisome matrix, docking	7.923566e-4
GO:0002885	positive regulation of hypersensitivity	8.023082e-4
GO:0044240	multicellular organismal lipid catabolic process	8.061452e-4
GO:0051457	maintenance of protein location in nucleus	8.095666e-4
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis	8.217598e-4
GO:0006003	fructose 2,6-bisphosphate metabolic process	8.265974e-4
GO:0034442	regulation of lipoprotein oxidation	8.723134e-4
GO:0021978	telencephalon regionalization	8.731056e-4
GO:0031346	positive regulation of cell projection organization	8.767571e-4
GO:0035993	deltoid tuberosity development	8.963662e-4
GO:2000505	regulation of energy homeostasis	8.972965e-4
GO:0043134	regulation of hindgut contraction	9.227376e-4
GO:0006917	induction of apoptosis	9.289434e-4
GO:0012502	induction of programmed cell death	9.323612e-4
GO:0050746	regulation of lipoprotein metabolic process	1.008860e-3
GO:0006298	mismatch repair	1.008860e-3
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	1.050619e-3
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	1.050619e-3
GO:0090179	planar cell polarity pathway involved in neural tube closure	1.077941e-3
GO:0045661	regulation of myoblast differentiation	1.078301e-3
GO:0006406	mRNA export from nucleus	1.114781e-3
GO:0021871	forebrain regionalization	1.118880e-3
GO:0042276	error-prone translesion synthesis	1.133465e-3
GO:0031331	positive regulation of cellular catabolic process	1.172715e-3
GO:0042771	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis	1.175192e-3
GO:0044341	sodium-dependent phosphate transport	1.237836e-3
GO:0033211	adiponectin-mediated signaling pathway	1.260890e-3
GO:0060914	heart formation	1.299701e-3
GO:0007631	feeding behavior	1.306244e-3
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	1.336167e-3
GO:0045923	positive regulation of fatty acid metabolic process	1.338434e-3
GO:0007207	activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway	1.344573e-3
GO:0002542	Factor XII activation	1.344573e-3
GO:0007283	spermatogenesis	1.372058e-3
GO:0043091	L-arginine import	1.394499e-3
GO:0045342	MHC class II biosynthetic process	1.394499e-3
GO:0070839	divalent metal ion export	1.394499e-3
GO:0045751	negative regulation of Toll signaling pathway	1.394499e-3
GO:0035635	entry of bacterium into host cell	1.394499e-3
GO:0032632	interleukin-3 production	1.394499e-3
GO:0015707	nitrite transport	1.394499e-3
GO:0006876	cellular cadmium ion homeostasis	1.394499e-3
GO:0015761	mannose transport	1.394499e-3
GO:0008588	release of cytoplasmic sequestered NF-kappaB	1.404672e-3
GO:0072044	collecting duct development	1.430505e-3
GO:0046889	positive regulation of lipid biosynthetic process	1.456501e-3
GO:0017158	regulation of calcium ion-dependent exocytosis	1.500444e-3
GO:0035990	tendon cell differentiation	1.524915e-3
GO:0009642	response to light intensity	1.524915e-3
GO:0009629	response to gravity	1.566704e-3
GO:0050912	detection of chemical stimulus involved in sensory perception of taste	1.618929e-3
GO:0043570	maintenance of DNA repeat elements	1.618929e-3
GO:0015809	arginine transport	1.618929e-3
GO:0046660	female sex differentiation	1.621262e-3
GO:0001561	fatty acid alpha-oxidation	1.702580e-3
GO:0001764	neuron migration	1.708158e-3
GO:0051006	positive regulation of lipoprotein lipase activity	1.712969e-3
GO:0070301	cellular response to hydrogen peroxide	1.720966e-3
GO:0051919	positive regulation of fibrinolysis	1.757071e-3
GO:0042696	menarche	1.757071e-3
GO:0006379	mRNA cleavage	1.859349e-3
GO:0031573	intra-S DNA damage checkpoint	2.005138e-3
GO:0050863	regulation of T cell activation	2.032369e-3
GO:0018065	protein-cofactor linkage	2.048781e-3
GO:0051177	meiotic sister chromatid cohesion	2.069064e-3
GO:0032203	telomere formation via telomerase	2.069064e-3
GO:0000079	regulation of cyclin-dependent protein kinase activity	2.094149e-3
GO:0050665	hydrogen peroxide biosynthetic process	2.128269e-3
GO:0007276	gamete generation	2.140848e-3
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	2.156632e-3
GO:0043524	negative regulation of neuron apoptosis	2.196265e-3
GO:0018963	phthalate metabolic process	2.217020e-3
GO:0021766	hippocampus development	2.222517e-3
GO:0006398	histone mRNA 3'-end processing	2.234437e-3
GO:0046545	development of primary female sexual characteristics	2.250051e-3
GO:0010721	negative regulation of cell development	2.267418e-3
GO:0051704	multi-organism process	2.276375e-3
GO:0010970	microtubule-based transport	2.346813e-3
GO:0060319	primitive erythrocyte differentiation	2.349548e-3
GO:2000522	positive regulation of immunological synapse formation	2.369407e-3
GO:0010259	multicellular organismal aging	2.413335e-3
GO:0009409	response to cold	2.440391e-3
GO:0022414	reproductive process	2.461830e-3
GO:0050772	positive regulation of axonogenesis	2.493769e-3
GO:0045779	negative regulation of bone resorption	2.503932e-3
GO:0021798	forebrain dorsal/ventral pattern formation	2.514635e-3
GO:0043056	forward locomotion	2.520911e-3
GO:0010288	response to lead ion	2.526460e-3
GO:0009187	cyclic nucleotide metabolic process	2.606927e-3
GO:0090185	negative regulation of kidney development	2.624176e-3
GO:0021759	globus pallidus development	2.624176e-3
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	2.635355e-3
GO:0001913	T cell mediated cytotoxicity	2.697834e-3
GO:0032107	regulation of response to nutrient levels	2.736703e-3
GO:0061005	cell differentiation involved in kidney development	2.742161e-3
GO:0010871	negative regulation of receptor biosynthetic process	2.751977e-3
GO:0001817	regulation of cytokine production	2.758827e-3
GO:2000507	positive regulation of energy homeostasis	2.765234e-3
GO:2000253	positive regulation of feeding behavior	2.765234e-3
GO:0002344	B cell affinity maturation	2.765234e-3
GO:0050917	sensory perception of umami taste	2.799072e-3
GO:0042036	negative regulation of cytokine biosynthetic process	2.800705e-3
GO:0007548	sex differentiation	2.853482e-3
GO:0072595	maintenance of protein localization to organelle	2.883077e-3
GO:0010611	regulation of cardiac muscle hypertrophy	2.898397e-3
GO:0015746	citrate transport	2.923637e-3
GO:0050829	defense response to Gram-negative bacterium	2.932880e-3
GO:0002579	positive regulation of antigen processing and presentation	2.938094e-3
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	3.078030e-3
GO:0006167	AMP biosynthetic process	3.131122e-3
GO:0045085	negative regulation of interleukin-2 biosynthetic process	3.167248e-3
GO:0006646	phosphatidylethanolamine biosynthetic process	3.169056e-3
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	3.180230e-3
GO:0047496	vesicle transport along microtubule	3.180230e-3
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion	3.183631e-3
GO:0046079	dUMP catabolic process	3.183631e-3
GO:0002883	regulation of hypersensitivity	3.196735e-3
GO:0043555	regulation of translation in response to stress	3.261043e-3
GO:0010388	cullin deneddylation	3.261043e-3
GO:0090031	positive regulation of steroid hormone biosynthetic process	3.426001e-3
GO:0051707	response to other organism	3.449960e-3
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	3.466840e-3
GO:0006867	asparagine transport	3.466840e-3
GO:0048663	neuron fate commitment	3.476012e-3
GO:0060026	convergent extension	3.479546e-3
GO:0071733	transcriptional activation by promoter-enhancer looping	3.489423e-3
GO:0043615	astrocyte cell migration	3.489423e-3
GO:0045072	regulation of interferon-gamma biosynthetic process	3.490686e-3
GO:0044130	negative regulation of growth of symbiont in host	3.591447e-3
GO:0007162	negative regulation of cell adhesion	3.614047e-3
GO:0002891	positive regulation of immunoglobulin mediated immune response	3.759715e-3
GO:0034720	histone H3-K4 demethylation	3.793698e-3
GO:0010092	specification of organ identity	3.894372e-3
GO:0072161	mesenchymal cell differentiation involved in kidney development	3.903990e-3
GO:0060684	epithelial-mesenchymal cell signaling	3.971168e-3
GO:0010896	regulation of triglyceride catabolic process	4.073033e-3
GO:0002762	negative regulation of myeloid leukocyte differentiation	4.169782e-3
GO:0010812	negative regulation of cell-substrate adhesion	4.172257e-3
GO:0046640	regulation of alpha-beta T cell proliferation	4.247685e-3
GO:0060586	multicellular organismal iron ion homeostasis	4.249220e-3
GO:0014807	regulation of somitogenesis	4.249220e-3
GO:0003270	Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation	4.249220e-3
GO:0016577	histone demethylation	4.269626e-3
GO:0080135	regulation of cellular response to stress	4.331724e-3
GO:0070169	positive regulation of biomineral tissue development	4.375931e-3
GO:0018879	biphenyl metabolic process	4.429635e-3
GO:0033131	regulation of glucokinase activity	4.432692e-3
GO:0003130	BMP signaling pathway involved in heart induction	4.441329e-3
GO:0008406	gonad development	4.584288e-3
GO:0045137	development of primary sexual characteristics	4.593140e-3
GO:0014743	regulation of muscle hypertrophy	4.747700e-3
GO:0046033	AMP metabolic process	4.755516e-3
GO:0007029	endoplasmic reticulum organization	4.790902e-3
GO:0021854	hypothalamus development	4.793404e-3
GO:0008088	axon cargo transport	4.836500e-3
GO:0046686	response to cadmium ion	4.896802e-3
GO:0045940	positive regulation of steroid metabolic process	4.955879e-3
GO:0006013	mannose metabolic process	4.982033e-3
GO:0035087	siRNA loading onto RISC involved in RNA interference	5.014109e-3
GO:0010836	negative regulation of protein ADP-ribosylation	5.014109e-3
GO:0010106	cellular response to iron ion starvation	5.014109e-3
GO:0001780	neutrophil homeostasis	5.016680e-3
GO:0001541	ovarian follicle development	5.157460e-3
GO:0035644	phosphoanandamide dephosphorylation	5.157982e-3
GO:0072593	reactive oxygen species metabolic process	5.171907e-3
GO:0061311	cell surface receptor linked signaling pathway involved in heart development	5.177456e-3
GO:0009607	response to biotic stimulus	5.309858e-3
GO:0045955	negative regulation of calcium ion-dependent exocytosis	5.329424e-3
GO:0090292	nuclear matrix anchoring at nuclear membrane	5.348082e-3
GO:0071422	succinate transmembrane transport	5.348082e-3
GO:0055114	oxidation-reduction process	5.515500e-3
GO:0060339	negative regulation of type I interferon-mediated signaling pathway	5.532056e-3
GO:0051705	behavioral interaction between organisms	5.759028e-3
GO:0016071	mRNA metabolic process	5.871487e-3
GO:0050768	negative regulation of neurogenesis	5.895346e-3
GO:0072384	organelle transport along microtubule	5.949810e-3
GO:0032570	response to progesterone stimulus	5.977198e-3
GO:0014012	peripheral nervous system axon regeneration	6.027429e-3
GO:0001909	leukocyte mediated cytotoxicity	6.027429e-3
GO:0009159	deoxyribonucleoside monophosphate catabolic process	6.031745e-3
GO:0033274	response to vitamin B2	6.031745e-3
GO:0002708	positive regulation of lymphocyte mediated immunity	6.094501e-3
GO:0045116	protein neddylation	6.255561e-3
GO:0043922	negative regulation by host of viral transcription	6.271937e-3
GO:0072205	metanephric collecting duct development	6.271937e-3
GO:0007159	leukocyte cell-cell adhesion	6.322372e-3
GO:0010720	positive regulation of cell development	6.477789e-3
GO:0035634	response to stilbenoid	6.628127e-3
GO:0070633	transepithelial transport	6.637382e-3
GO:0006658	phosphatidylserine metabolic process	6.706689e-3
GO:0050684	regulation of mRNA processing	6.837299e-3
GO:0002309	T cell proliferation involved in immune response	6.871963e-3
GO:0000395	nuclear mRNA 5'-splice site recognition	6.898186e-3
GO:0002573	myeloid leukocyte differentiation	6.901642e-3
GO:0010948	negative regulation of cell cycle process	6.910794e-3
GO:0007035	vacuolar acidification	6.978303e-3
GO:0032897	negative regulation of viral transcription	6.978438e-3
GO:0006749	glutathione metabolic process	7.085449e-3
GO:0010594	regulation of endothelial cell migration	7.180062e-3
GO:0006397	mRNA processing	7.234777e-3
GO:0015874	norepinephrine transport	7.298706e-3
GO:0006482	protein demethylation	7.337880e-3
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	7.352531e-3
GO:0018894	dibenzo-p-dioxin metabolic process	7.400399e-3
GO:0001798	positive regulation of type IIa hypersensitivity	7.400399e-3
GO:0055025	positive regulation of cardiac muscle tissue development	7.402641e-3
GO:0048511	rhythmic process	7.413102e-3
GO:0006661	phosphatidylinositol biosynthetic process	7.526766e-3
GO:0003219	cardiac right ventricle formation	7.664251e-3
GO:0016446	somatic hypermutation of immunoglobulin genes	7.746050e-3
GO:0070079	histone H4-R3 demethylation	7.836715e-3
GO:0070078	histone H3-R2 demethylation	7.836715e-3
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	7.836715e-3
GO:0050769	positive regulation of neurogenesis	7.986919e-3
GO:0002819	regulation of adaptive immune response	8.045493e-3
GO:0001768	establishment of T cell polarity	8.053440e-3
GO:0007626	locomotory behavior	8.091496e-3
GO:0051240	positive regulation of multicellular organismal process	8.132102e-3
GO:0043901	negative regulation of multi-organism process	8.165940e-3
GO:0032663	regulation of interleukin-2 production	8.372293e-3
GO:0040015	negative regulation of multicellular organism growth	8.408585e-3
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	8.439093e-3
GO:0043558	regulation of translational initiation in response to stress	8.439093e-3
GO:0035694	mitochondrial protein catabolic process	8.439093e-3
GO:0045618	positive regulation of keratinocyte differentiation	8.467592e-3
GO:0010889	regulation of sequestering of triglyceride	8.491778e-3
GO:0010976	positive regulation of neuron projection development	8.635956e-3
GO:0045638	negative regulation of myeloid cell differentiation	8.749131e-3
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	8.762718e-3
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	8.762718e-3
GO:0015747	urate transport	8.762718e-3
GO:0071674	mononuclear cell migration	8.925941e-3
GO:0060335	positive regulation of interferon-gamma-mediated signaling pathway	8.925941e-3
GO:0010034	response to acetate	8.925941e-3
GO:0032070	regulation of deoxyribonuclease activity	8.925941e-3
GO:0006491	N-glycan processing	8.957097e-3
GO:0007221	positive regulation of transcription of Notch receptor target	8.962870e-3
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	8.978271e-3
GO:0045603	positive regulation of endothelial cell differentiation	9.072588e-3
GO:0002861	regulation of inflammatory response to antigenic stimulus	9.185562e-3
GO:0006750	glutathione biosynthetic process	9.231748e-3
GO:0072332	signal transduction by p53 class mediator resulting in induction of apoptosis	9.246384e-3
GO:0071900	regulation of protein serine/threonine kinase activity	9.418840e-3
GO:0048545	response to steroid hormone stimulus	9.595201e-3
GO:0050670	regulation of lymphocyte proliferation	9.652433e-3
GO:0033133	positive regulation of glucokinase activity	9.770989e-3
GO:0032308	positive regulation of prostaglandin secretion	9.770989e-3
GO:0046328	regulation of JNK cascade	9.822372e-3
GO:0050672	negative regulation of lymphocyte proliferation	9.986505e-3
GO:0045004	DNA replication proofreading	1.000148e-2
GO:0034721	histone H3-K4 demethylation, trimethyl-H3-K4-specific	1.000148e-2
GO:0015939	pantothenate metabolic process	1.000148e-2
GO:0019047	provirus integration	1.000148e-2
GO:0045162	clustering of voltage-gated sodium channels	1.021185e-2
GO:0019348	dolichol metabolic process	1.021185e-2
GO:0090208	positive regulation of triglyceride metabolic process	1.025498e-2
GO:0070988	demethylation	1.027499e-2
GO:0034614	cellular response to reactive oxygen species	1.059716e-2
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	1.063596e-2
GO:0009062	fatty acid catabolic process	1.066239e-2
GO:0090238	positive regulation of arachidonic acid secretion	1.069207e-2
GO:0035262	gonad morphogenesis	1.069207e-2
GO:0002125	maternal aggressive behavior	1.069207e-2
GO:0008380	RNA splicing	1.081255e-2
GO:0042274	ribosomal small subunit biogenesis	1.086409e-2
GO:0032892	positive regulation of organic acid transport	1.088311e-2
GO:0006972	hyperosmotic response	1.088311e-2
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	1.093134e-2
GO:0042770	signal transduction in response to DNA damage	1.100054e-2
GO:0019882	antigen processing and presentation	1.104398e-2
GO:0031247	actin rod assembly	1.121833e-2
GO:0032944	regulation of mononuclear cell proliferation	1.127971e-2
GO:0033058	directional locomotion	1.130462e-2
GO:0032680	regulation of tumor necrosis factor production	1.132451e-2
GO:0045404	positive regulation of interleukin-4 biosynthetic process	1.137512e-2
GO:0006672	ceramide metabolic process	1.142369e-2
GO:0031953	negative regulation of protein autophosphorylation	1.144514e-2
GO:0048710	regulation of astrocyte differentiation	1.146349e-2
GO:0072143	mesangial cell development	1.150234e-2
GO:0070584	mitochondrion morphogenesis	1.150234e-2
GO:0034629	cellular protein complex localization	1.150234e-2
GO:0009725	response to hormone stimulus	1.150580e-2
GO:0032355	response to estradiol stimulus	1.159210e-2
GO:0070302	regulation of stress-activated protein kinase signaling cascade	1.160247e-2
GO:0040014	regulation of multicellular organism growth	1.177030e-2
GO:0043523	regulation of neuron apoptosis	1.196016e-2
GO:0001956	positive regulation of neurotransmitter secretion	1.201841e-2
GO:0030099	myeloid cell differentiation	1.203276e-2
GO:0070664	negative regulation of leukocyte proliferation	1.209880e-2
GO:0045577	regulation of B cell differentiation	1.222347e-2
GO:0042542	response to hydrogen peroxide	1.228273e-2
GO:0071108	protein K48-linked deubiquitination	1.268501e-2
GO:0008343	adult feeding behavior	1.268501e-2
GO:0034372	very-low-density lipoprotein particle remodeling	1.271466e-2
GO:0048791	calcium ion-dependent exocytosis of neurotransmitter	1.283088e-2
GO:0046851	negative regulation of bone remodeling	1.283088e-2
GO:0030252	growth hormone secretion	1.295700e-2
GO:0042559	pteridine-containing compound biosynthetic process	1.295813e-2
GO:0007595	lactation	1.300379e-2
GO:0045778	positive regulation of ossification	1.305155e-2
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	1.348611e-2
GO:0035967	cellular response to topologically incorrect protein	1.350352e-2
GO:0022602	ovulation cycle process	1.359154e-2
GO:0050855	regulation of B cell receptor signaling pathway	1.372749e-2
GO:0009404	toxin metabolic process	1.383165e-2
GO:0042698	ovulation cycle	1.385073e-2
GO:0045017	glycerolipid biosynthetic process	1.386826e-2
GO:0021930	cerebellar granule cell precursor proliferation	1.388098e-2
GO:0032095	regulation of response to food	1.392405e-2
GO:0048668	collateral sprouting	1.393751e-2
GO:0015817	histidine transport	1.393751e-2
GO:0070663	regulation of leukocyte proliferation	1.403713e-2
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	1.404760e-2
GO:0071157	negative regulation of cell cycle arrest	1.410507e-2
GO:0032847	regulation of cellular pH reduction	1.410507e-2