Novel motif:167

name:	motif167_TTGGGTAGGAG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	5.775526e-20
GO:0002678	positive regulation of chronic inflammatory response	1.072400e-17
GO:0002676	regulation of chronic inflammatory response	1.168606e-16
GO:0045994	positive regulation of translational initiation by iron	1.549944e-16
GO:0002037	negative regulation of L-glutamate transport	1.549944e-16
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	1.170462e-15
GO:0002036	regulation of L-glutamate transport	5.065836e-15
GO:0006447	regulation of translational initiation by iron	8.645186e-15
GO:0051956	negative regulation of amino acid transport	1.259555e-13
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	4.211980e-12
GO:0043149	stress fiber assembly	6.029035e-12
GO:0051955	regulation of amino acid transport	1.525061e-10
GO:0032321	positive regulation of Rho GTPase activity	2.639275e-10
GO:0046325	negative regulation of glucose import	3.627393e-10
GO:0003009	skeletal muscle contraction	6.107259e-10
GO:0045948	positive regulation of translational initiation	6.424082e-10
GO:0032012	regulation of ARF protein signal transduction	1.850898e-9
GO:0051054	positive regulation of DNA metabolic process	2.048489e-9
GO:0032863	activation of Rac GTPase activity	2.145083e-9
GO:0002889	regulation of immunoglobulin mediated immune response	3.158015e-9
GO:0032862	activation of Rho GTPase activity	3.172689e-9
GO:0044070	regulation of anion transport	3.258746e-9
GO:0002712	regulation of B cell mediated immunity	4.074633e-9
GO:0032319	regulation of Rho GTPase activity	4.607769e-9
GO:0032203	telomere formation via telomerase	6.188343e-9
GO:0032855	positive regulation of Rac GTPase activity	6.204598e-9
GO:0051798	positive regulation of hair follicle development	1.121937e-8
GO:0045684	positive regulation of epidermis development	1.180104e-8
GO:0060688	regulation of morphogenesis of a branching structure	5.025060e-8
GO:0007184	SMAD protein import into nucleus	5.179558e-8
GO:0060351	cartilage development involved in endochondral bone morphogenesis	6.093538e-8
GO:0002149	hypochlorous acid biosynthetic process	7.066784e-8
GO:0030221	basophil differentiation	8.756743e-8
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	1.699189e-7
GO:0045911	positive regulation of DNA recombination	2.091491e-7
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	2.352560e-7
GO:0030853	negative regulation of granulocyte differentiation	2.444539e-7
GO:0050881	musculoskeletal movement	2.601258e-7
GO:0032233	positive regulation of actin filament bundle assembly	2.871491e-7
GO:0030198	extracellular matrix organization	3.013603e-7
GO:0002703	regulation of leukocyte mediated immunity	3.070972e-7
GO:0032202	telomere assembly	3.766588e-7
GO:0044130	negative regulation of growth of symbiont in host	4.026524e-7
GO:0033209	tumor necrosis factor-mediated signaling pathway	4.217786e-7
GO:0010742	macrophage derived foam cell differentiation	4.992845e-7
GO:2000736	regulation of stem cell differentiation	4.998987e-7
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	5.180695e-7
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	6.685979e-7
GO:0035814	negative regulation of renal sodium excretion	8.285821e-7
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	8.812612e-7
GO:0051023	regulation of immunoglobulin secretion	8.840582e-7
GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	9.055857e-7
GO:0000185	activation of MAPKKK activity	1.212024e-6
GO:0045830	positive regulation of isotype switching	1.254718e-6
GO:0045840	positive regulation of mitosis	1.600839e-6
GO:2000573	positive regulation of DNA biosynthetic process	1.629336e-6
GO:0051532	regulation of NFAT protein import into nucleus	1.973246e-6
GO:0051953	negative regulation of amine transport	1.990032e-6
GO:2000353	positive regulation of endothelial cell apoptosis	2.231263e-6
GO:0044319	wound healing, spreading of cells	2.348666e-6
GO:0009443	pyridoxal 5'-phosphate salvage	2.807049e-6
GO:0002706	regulation of lymphocyte mediated immunity	2.848174e-6
GO:0043243	positive regulation of protein complex disassembly	3.255575e-6
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	3.622640e-6
GO:0072289	metanephric nephron tubule formation	4.018495e-6
GO:0035023	regulation of Rho protein signal transduction	4.555906e-6
GO:0072284	metanephric S-shaped body morphogenesis	4.709584e-6
GO:0015816	glycine transport	4.709584e-6
GO:0051899	membrane depolarization	5.274691e-6
GO:0051972	regulation of telomerase activity	5.303277e-6
GO:0002920	regulation of humoral immune response	6.135438e-6
GO:0061048	negative regulation of branching involved in lung morphogenesis	6.180545e-6
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	6.265553e-6
GO:0051797	regulation of hair follicle development	6.413326e-6
GO:0072044	collecting duct development	6.802431e-6
GO:0072040	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis	7.095081e-6
GO:0042823	pyridoxal phosphate biosynthetic process	7.241959e-6
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	7.312963e-6
GO:0002697	regulation of immune effector process	8.157643e-6
GO:0045682	regulation of epidermis development	8.569517e-6
GO:0031444	slow-twitch skeletal muscle fiber contraction	9.145352e-6
GO:0035313	wound healing, spreading of epidermal cells	9.355087e-6
GO:0042137	sequestering of neurotransmitter	9.633134e-6
GO:0006984	ER-nucleus signaling pathway	9.901593e-6
GO:0006006	glucose metabolic process	1.022904e-5
GO:0016577	histone demethylation	1.085796e-5
GO:0051924	regulation of calcium ion transport	1.088662e-5
GO:0010629	negative regulation of gene expression	1.216067e-5
GO:0060348	bone development	1.264437e-5
GO:0032856	activation of Ras GTPase activity	1.329351e-5
GO:0043299	leukocyte degranulation	1.358767e-5
GO:0010829	negative regulation of glucose transport	1.374187e-5
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	1.405594e-5
GO:0035691	macrophage migration inhibitory factor signaling pathway	1.405594e-5
GO:0019264	glycine biosynthetic process from serine	1.405594e-5
GO:0002432	granuloma formation	1.462875e-5
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	1.471948e-5
GO:0043901	negative regulation of multi-organism process	1.530146e-5
GO:0010523	negative regulation of calcium ion transport into cytosol	1.532997e-5
GO:0008078	mesodermal cell migration	1.637212e-5
GO:0014908	myotube differentiation involved in skeletal muscle regeneration	1.869435e-5
GO:0072003	kidney rudiment formation	1.883351e-5
GO:0060349	bone morphogenesis	2.155664e-5
GO:0002891	positive regulation of immunoglobulin mediated immune response	2.248744e-5
GO:0060350	endochondral bone morphogenesis	2.353018e-5
GO:0021554	optic nerve development	2.430366e-5
GO:0002679	respiratory burst involved in defense response	2.480036e-5
GO:0016926	protein desumoylation	2.622730e-5
GO:0018277	protein deamination	2.686464e-5
GO:0046578	regulation of Ras protein signal transduction	2.882179e-5
GO:0072305	negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis	3.051117e-5
GO:2000594	positive regulation of metanephric DCT cell differentiation	3.051117e-5
GO:0039003	pronephric field specification	3.051117e-5
GO:0051952	regulation of amine transport	3.053957e-5
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	3.133275e-5
GO:0007009	plasma membrane organization	3.223298e-5
GO:0051365	cellular response to potassium ion starvation	3.278878e-5
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	3.352168e-5
GO:0072017	distal tubule development	3.367000e-5
GO:0002698	negative regulation of immune effector process	3.648167e-5
GO:0072278	metanephric comma-shaped body morphogenesis	3.694421e-5
GO:0002921	negative regulation of humoral immune response	3.732104e-5
GO:0002819	regulation of adaptive immune response	3.859815e-5
GO:0001941	postsynaptic membrane organization	4.086326e-5
GO:0010638	positive regulation of organelle organization	4.336188e-5
GO:0006658	phosphatidylserine metabolic process	4.571867e-5
GO:0010717	regulation of epithelial to mesenchymal transition	4.608291e-5
GO:0060561	apoptosis involved in morphogenesis	4.655581e-5
GO:0070988	demethylation	4.695069e-5
GO:0055026	negative regulation of cardiac muscle tissue development	5.030092e-5
GO:0048382	mesendoderm development	5.033282e-5
GO:0007196	inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway	5.033282e-5
GO:0071418	cellular response to amine stimulus	5.442040e-5
GO:0032793	positive regulation of CREB transcription factor activity	5.521362e-5
GO:0006482	protein demethylation	5.608222e-5
GO:0021697	cerebellar cortex formation	5.684370e-5
GO:0051764	actin crosslink formation	5.718117e-5
GO:0051152	positive regulation of smooth muscle cell differentiation	6.332838e-5
GO:0070483	detection of hypoxia	6.341131e-5
GO:0043922	negative regulation by host of viral transcription	6.344162e-5
GO:0002861	regulation of inflammatory response to antigenic stimulus	6.394304e-5
GO:0006360	transcription from RNA polymerase I promoter	6.394304e-5
GO:0032231	regulation of actin filament bundle assembly	6.423724e-5
GO:0001916	positive regulation of T cell mediated cytotoxicity	6.702369e-5
GO:0071299	cellular response to vitamin A	6.944199e-5
GO:0071417	cellular response to organic nitrogen	7.174796e-5
GO:0031953	negative regulation of protein autophosphorylation	7.207609e-5
GO:0045799	positive regulation of chromatin assembly or disassembly	7.528517e-5
GO:0051533	positive regulation of NFAT protein import into nucleus	7.588256e-5
GO:0046814	virion attachment, binding of host cell surface coreceptor	7.731829e-5
GO:0048554	positive regulation of metalloenzyme activity	8.040342e-5
GO:0032094	response to food	8.177957e-5
GO:0051253	negative regulation of RNA metabolic process	8.722952e-5
GO:0048168	regulation of neuronal synaptic plasticity	8.884364e-5
GO:2000612	regulation of thyroid-stimulating hormone secretion	8.951338e-5
GO:0045055	regulated secretory pathway	9.114716e-5
GO:0002579	positive regulation of antigen processing and presentation	9.115732e-5
GO:0072207	metanephric epithelium development	9.212955e-5
GO:0006983	ER overload response	9.305999e-5
GO:0032836	glomerular basement membrane development	9.526413e-5
GO:0034551	mitochondrial respiratory chain complex III assembly	9.757152e-5
GO:0051973	positive regulation of telomerase activity	1.091372e-4
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.091493e-4
GO:0035021	negative regulation of Rac protein signal transduction	1.182609e-4
GO:0007509	mesoderm migration involved in gastrulation	1.202400e-4
GO:0051926	negative regulation of calcium ion transport	1.202884e-4
GO:0014739	positive regulation of muscle hyperplasia	1.219297e-4
GO:0043403	skeletal muscle tissue regeneration	1.235497e-4
GO:2000465	regulation of glycogen (starch) synthase activity	1.363959e-4
GO:0031622	positive regulation of fever generation	1.513904e-4
GO:0046655	folic acid metabolic process	1.537788e-4
GO:0060707	trophoblast giant cell differentiation	1.598763e-4
GO:2000172	regulation of branching morphogenesis of a nerve	1.610751e-4
GO:0071300	cellular response to retinoic acid	1.621961e-4
GO:0031442	positive regulation of mRNA 3'-end processing	1.655371e-4
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	1.663717e-4
GO:2000178	negative regulation of neural precursor cell proliferation	1.679386e-4
GO:0090074	negative regulation of protein homodimerization activity	1.709912e-4
GO:0043932	ossification involved in bone remodeling	1.738971e-4
GO:0071474	cellular hyperosmotic response	1.773565e-4
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	1.778600e-4
GO:0001974	blood vessel remodeling	1.799688e-4
GO:0017004	cytochrome complex assembly	1.801596e-4
GO:0045556	positive regulation of TRAIL biosynthetic process	1.815192e-4
GO:0071104	response to interleukin-9	1.828728e-4
GO:0061144	alveolar secondary septum development	1.828728e-4
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	1.935059e-4
GO:0009817	defense response to fungus, incompatible interaction	1.935059e-4
GO:0072164	mesonephric tubule development	2.028233e-4
GO:0045892	negative regulation of transcription, DNA-dependent	2.068195e-4
GO:0031652	positive regulation of heat generation	2.148216e-4
GO:0071732	cellular response to nitric oxide	2.149787e-4
GO:0050912	detection of chemical stimulus involved in sensory perception of taste	2.150246e-4
GO:0042726	flavin-containing compound metabolic process	2.167435e-4
GO:0048839	inner ear development	2.174258e-4
GO:0032312	regulation of ARF GTPase activity	2.241237e-4
GO:0002761	regulation of myeloid leukocyte differentiation	2.316028e-4
GO:0021798	forebrain dorsal/ventral pattern formation	2.351749e-4
GO:0030851	granulocyte differentiation	2.363459e-4
GO:0021877	forebrain neuron fate commitment	2.378064e-4
GO:0034101	erythrocyte homeostasis	2.412469e-4
GO:0060708	spongiotrophoblast differentiation	2.435808e-4
GO:0010718	positive regulation of epithelial to mesenchymal transition	2.441976e-4
GO:0045066	regulatory T cell differentiation	2.555140e-4
GO:0031327	negative regulation of cellular biosynthetic process	2.642958e-4
GO:0030852	regulation of granulocyte differentiation	2.756070e-4
GO:0007406	negative regulation of neuroblast proliferation	2.779068e-4
GO:0007109	cytokinesis, completion of separation	2.782061e-4
GO:0048295	positive regulation of isotype switching to IgE isotypes	2.782061e-4
GO:0042696	menarche	2.815875e-4
GO:2000974	negative regulation of pro-B cell differentiation	2.846092e-4
GO:0034505	tooth mineralization	2.912648e-4
GO:0045112	integrin biosynthetic process	3.190635e-4
GO:0015670	carbon dioxide transport	3.290583e-4
GO:0042074	cell migration involved in gastrulation	3.326313e-4
GO:0009890	negative regulation of biosynthetic process	3.386582e-4
GO:0051172	negative regulation of nitrogen compound metabolic process	3.484997e-4
GO:0045650	negative regulation of macrophage differentiation	3.485117e-4
GO:0035854	eosinophil fate commitment	3.534633e-4
GO:0030222	eosinophil differentiation	3.534633e-4
GO:0035095	behavioral response to nicotine	3.554630e-4
GO:0045893	positive regulation of transcription, DNA-dependent	3.565695e-4
GO:0002830	positive regulation of type 2 immune response	3.606277e-4
GO:0032897	negative regulation of viral transcription	3.686026e-4
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	3.696081e-4
GO:0051173	positive regulation of nitrogen compound metabolic process	3.705579e-4
GO:0009892	negative regulation of metabolic process	3.760298e-4
GO:0030502	negative regulation of bone mineralization	3.805132e-4
GO:0010936	negative regulation of macrophage cytokine production	3.827837e-4
GO:0046533	negative regulation of photoreceptor cell differentiation	3.895182e-4
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	3.895182e-4
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	3.982310e-4
GO:0007613	memory	4.190924e-4
GO:0090341	negative regulation of secretion of lysosomal enzymes	4.194635e-4
GO:0045358	negative regulation of interferon-beta biosynthetic process	4.194635e-4
GO:0090188	negative regulation of pancreatic juice secretion	4.194635e-4
GO:0072195	kidney smooth muscle cell differentiation	4.303426e-4
GO:0072105	ureteric peristalsis	4.303426e-4
GO:0072668	tubulin complex biogenesis	4.306759e-4
GO:0071470	cellular response to osmotic stress	4.356806e-4
GO:0071230	cellular response to amino acid stimulus	4.541837e-4
GO:0002513	tolerance induction to self antigen	4.582965e-4
GO:0060712	spongiotrophoblast layer development	4.649481e-4
GO:0060364	frontal suture morphogenesis	4.812104e-4
GO:0021535	cell migration in hindbrain	4.968614e-4
GO:0051339	regulation of lyase activity	5.186910e-4
GO:0034499	late endosome to Golgi transport	5.352407e-4
GO:0071955	recycling endosome to Golgi transport	5.352407e-4
GO:0046626	regulation of insulin receptor signaling pathway	5.369802e-4
GO:0072132	mesenchyme morphogenesis	5.457564e-4
GO:0045657	positive regulation of monocyte differentiation	5.483664e-4
GO:0030218	erythrocyte differentiation	5.571015e-4
GO:0045059	positive thymic T cell selection	5.772949e-4
GO:2000177	regulation of neural precursor cell proliferation	5.871435e-4
GO:0016925	protein sumoylation	5.936260e-4
GO:0072205	metanephric collecting duct development	6.019111e-4
GO:0051017	actin filament bundle assembly	6.251596e-4
GO:0006565	L-serine catabolic process	6.271556e-4
GO:0072282	metanephric nephron tubule morphogenesis	6.280554e-4
GO:0050765	negative regulation of phagocytosis	6.352819e-4
GO:0009637	response to blue light	6.383090e-4
GO:2000077	negative regulation of type B pancreatic cell development	6.415044e-4
GO:2000188	regulation of cholesterol homeostasis	6.716683e-4
GO:0048352	paraxial mesoderm structural organization	6.716683e-4
GO:0021998	neural plate mediolateral regionalization	6.716683e-4
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	6.771034e-4
GO:0071383	cellular response to steroid hormone stimulus	6.781166e-4
GO:0002637	regulation of immunoglobulin production	6.799813e-4
GO:2000463	positive regulation of excitatory postsynaptic membrane potential	6.814147e-4
GO:0002478	antigen processing and presentation of exogenous peptide antigen	6.850123e-4
GO:0035418	protein localization to synapse	6.968951e-4
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	7.051860e-4
GO:0007216	metabotropic glutamate receptor signaling pathway	7.075439e-4
GO:0001914	regulation of T cell mediated cytotoxicity	7.300823e-4
GO:2000036	regulation of stem cell maintenance	7.335013e-4
GO:0005996	monosaccharide metabolic process	7.620468e-4
GO:0008624	induction of apoptosis by extracellular signals	7.700425e-4
GO:0006032	chitin catabolic process	7.829936e-4
GO:0016576	histone dephosphorylation	8.037230e-4
GO:0009082	branched chain family amino acid biosynthetic process	8.189765e-4
GO:0030279	negative regulation of ossification	8.539033e-4
GO:0072553	terminal button organization	8.542245e-4
GO:0030834	regulation of actin filament depolymerization	8.574652e-4
GO:2000467	positive regulation of glycogen (starch) synthase activity	8.623058e-4
GO:0070168	negative regulation of biomineral tissue development	8.661888e-4
GO:0021631	optic nerve morphogenesis	9.129802e-4
GO:0010605	negative regulation of macromolecule metabolic process	9.373040e-4
GO:0043314	negative regulation of neutrophil degranulation	9.526296e-4
GO:0014807	regulation of somitogenesis	9.798908e-4
GO:0031952	regulation of protein autophosphorylation	9.824234e-4
GO:0001823	mesonephros development	9.863489e-4
GO:0035026	leading edge cell differentiation	1.018841e-3
GO:0090102	cochlea development	1.035105e-3
GO:0071242	cellular response to ammonium ion	1.035937e-3
GO:0010960	magnesium ion homeostasis	1.035937e-3
GO:0019064	viral envelope fusion with host membrane	1.040064e-3
GO:0042593	glucose homeostasis	1.058799e-3
GO:0021681	cerebellar granular layer development	1.066494e-3
GO:0072170	metanephric tubule development	1.072272e-3
GO:0071218	cellular response to misfolded protein	1.077677e-3
GO:0051181	cofactor transport	1.105004e-3
GO:0031279	regulation of cyclase activity	1.111540e-3
GO:0003084	positive regulation of systemic arterial blood pressure	1.122197e-3
GO:0046796	viral genome transport in host cell	1.127147e-3
GO:0032571	response to vitamin K	1.127147e-3
GO:0031670	cellular response to nutrient	1.148181e-3
GO:0042634	regulation of hair cycle	1.180004e-3
GO:0035522	monoubiquitinated histone H2A deubiquitination	1.188033e-3
GO:0043000	Golgi to plasma membrane CFTR protein transport	1.188033e-3
GO:0045920	negative regulation of exocytosis	1.201196e-3
GO:0032318	regulation of Ras GTPase activity	1.211030e-3
GO:0003106	negative regulation of glomerular filtration by angiotensin	1.218687e-3
GO:0014895	smooth muscle hypertrophy	1.218687e-3
GO:0006972	hyperosmotic response	1.240773e-3
GO:0045626	negative regulation of T-helper 1 cell differentiation	1.261768e-3
GO:0043525	positive regulation of neuron apoptosis	1.273585e-3
GO:0002922	positive regulation of humoral immune response	1.301605e-3
GO:0021707	cerebellar granule cell differentiation	1.310824e-3
GO:0048384	retinoic acid receptor signaling pathway	1.317367e-3
GO:0042428	serotonin metabolic process	1.320961e-3
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	1.349101e-3
GO:0019049	evasion of host defenses by virus	1.353890e-3
GO:0003203	endocardial cushion morphogenesis	1.355946e-3
GO:0016570	histone modification	1.366182e-3
GO:0007159	leukocyte cell-cell adhesion	1.385432e-3
GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	1.390917e-3
GO:0032736	positive regulation of interleukin-13 production	1.408698e-3
GO:0032332	positive regulation of chondrocyte differentiation	1.431174e-3
GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	1.468502e-3
GO:0072234	metanephric nephron tubule development	1.497043e-3
GO:0060319	primitive erythrocyte differentiation	1.500956e-3
GO:0002575	basophil chemotaxis	1.500956e-3
GO:0046968	peptide antigen transport	1.505754e-3
GO:0019046	reactivation of latent virus	1.505754e-3
GO:0019318	hexose metabolic process	1.508589e-3
GO:0016569	covalent chromatin modification	1.528555e-3
GO:0016568	chromatin modification	1.532169e-3
GO:2000737	negative regulation of stem cell differentiation	1.541962e-3
GO:0071803	positive regulation of podosome assembly	1.543673e-3
GO:0021759	globus pallidus development	1.543673e-3
GO:0010628	positive regulation of gene expression	1.565505e-3
GO:0021702	cerebellar Purkinje cell differentiation	1.588967e-3
GO:0021533	cell differentiation in hindbrain	1.610211e-3
GO:0060370	susceptibility to T cell mediated cytotoxicity	1.613826e-3
GO:0060693	regulation of branching involved in salivary gland morphogenesis	1.631618e-3
GO:0019556	histidine catabolic process to glutamate and formamide	1.665050e-3
GO:0001845	phagolysosome assembly	1.678232e-3
GO:0051254	positive regulation of RNA metabolic process	1.685500e-3
GO:0034976	response to endoplasmic reticulum stress	1.687121e-3
GO:0034198	cellular response to amino acid starvation	1.697159e-3
GO:0051927	negative regulation of calcium ion transport via voltage-gated calcium channel activity	1.702285e-3
GO:0045761	regulation of adenylate cyclase activity	1.717923e-3
GO:0010720	positive regulation of cell development	1.738651e-3
GO:0048680	positive regulation of axon regeneration	1.743446e-3
GO:0045806	negative regulation of endocytosis	1.759044e-3
GO:0071295	cellular response to vitamin	1.767071e-3
GO:0072221	metanephric distal convoluted tubule development	1.807498e-3
GO:0010046	response to mycotoxin	1.809298e-3
GO:0000053	argininosuccinate metabolic process	1.809298e-3
GO:0045649	regulation of macrophage differentiation	1.816617e-3
GO:0007492	endoderm development	1.843273e-3
GO:2000286	receptor internalization involved in canonical Wnt receptor signaling pathway	1.872380e-3
GO:0006836	neurotransmitter transport	1.887627e-3
GO:0071316	cellular response to nicotine	1.898906e-3
GO:0003416	endochondral bone growth	1.899941e-3
GO:0030513	positive regulation of BMP signaling pathway	1.920410e-3
GO:0060993	kidney morphogenesis	1.936005e-3
GO:0060338	regulation of type I interferon-mediated signaling pathway	1.948037e-3
GO:0035129	post-embryonic hindlimb morphogenesis	1.986886e-3
GO:0033617	mitochondrial respiratory chain complex IV assembly	1.986886e-3
GO:0008052	sensory organ boundary specification	1.986886e-3
GO:0006746	FADH2 metabolic process	1.986886e-3
GO:0003338	metanephros morphogenesis	2.054785e-3
GO:0060591	chondroblast differentiation	2.061055e-3
GO:0001505	regulation of neurotransmitter levels	2.068681e-3
GO:0035306	positive regulation of dephosphorylation	2.080925e-3
GO:0016578	histone deubiquitination	2.080925e-3
GO:0060557	positive regulation of vitamin D biosynthetic process	2.083524e-3
GO:0001672	regulation of chromatin assembly or disassembly	2.083524e-3
GO:0003229	ventricular cardiac muscle tissue development	2.087000e-3
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.132772e-3
GO:0031440	regulation of mRNA 3'-end processing	2.151400e-3
GO:0034435	cholesterol esterification	2.172928e-3
GO:0043320	natural killer cell degranulation	2.205915e-3
GO:0043973	histone H3-K4 acetylation	2.207565e-3
GO:0046985	positive regulation of hemoglobin biosynthetic process	2.207565e-3
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	2.207565e-3
GO:0030099	myeloid cell differentiation	2.212418e-3
GO:0045625	regulation of T-helper 1 cell differentiation	2.215520e-3
GO:0060346	bone trabecula formation	2.223849e-3
GO:0007129	synapsis	2.226133e-3
GO:0003188	heart valve formation	2.230605e-3
GO:0001880	Mullerian duct regression	2.246038e-3
GO:0046415	urate metabolic process	2.249646e-3
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	2.250577e-3
GO:0048535	lymph node development	2.306859e-3
GO:0001957	intramembranous ossification	2.306859e-3
GO:0090183	regulation of kidney development	2.312632e-3
GO:0072215	regulation of metanephros development	2.325700e-3
GO:0009895	negative regulation of catabolic process	2.339987e-3
GO:0045123	cellular extravasation	2.345621e-3
GO:0048298	positive regulation of isotype switching to IgA isotypes	2.347242e-3
GO:0060251	regulation of glial cell proliferation	2.347757e-3
GO:0071733	transcriptional activation by promoter-enhancer looping	2.431184e-3
GO:0010724	regulation of definitive erythrocyte differentiation	2.431184e-3
GO:0060997	dendritic spine morphogenesis	2.491623e-3
GO:0035356	cellular triglyceride homeostasis	2.509997e-3
GO:0035262	gonad morphogenesis	2.509997e-3
GO:0071312	cellular response to alkaloid	2.640777e-3
GO:0060334	regulation of interferon-gamma-mediated signaling pathway	2.718479e-3
GO:0017144	drug metabolic process	2.738546e-3
GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	2.739257e-3
GO:0009303	rRNA transcription	2.742519e-3
GO:0048486	parasympathetic nervous system development	2.759465e-3
GO:0019883	antigen processing and presentation of endogenous antigen	2.761583e-3
GO:0031536	positive regulation of exit from mitosis	2.783937e-3
GO:0035304	regulation of protein dephosphorylation	2.813475e-3
GO:0051534	negative regulation of NFAT protein import into nucleus	2.866214e-3
GO:0035307	positive regulation of protein dephosphorylation	2.879221e-3
GO:0048705	skeletal system morphogenesis	2.879494e-3
GO:0022009	central nervous system vasculogenesis	2.908817e-3
GO:0007193	inhibition of adenylate cyclase activity by G-protein signaling pathway	2.911092e-3
GO:0022617	extracellular matrix disassembly	2.944528e-3
GO:0021892	cerebral cortex GABAergic interneuron differentiation	2.998971e-3
GO:0010558	negative regulation of macromolecule biosynthetic process	3.024090e-3
GO:0007538	primary sex determination	3.062676e-3
GO:0002709	regulation of T cell mediated immunity	3.070222e-3
GO:0006515	misfolded or incompletely synthesized protein catabolic process	3.177500e-3
GO:0045161	neuronal ion channel clustering	3.200174e-3
GO:0045061	thymic T cell selection	3.247369e-3
GO:0001649	osteoblast differentiation	3.274223e-3
GO:0048793	pronephros development	3.307558e-3
GO:0043313	regulation of neutrophil degranulation	3.312658e-3
GO:0051928	positive regulation of calcium ion transport	3.404937e-3
GO:0002591	positive regulation of antigen processing and presentation of peptide antigen via MHC class I	3.441779e-3
GO:0002489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent	3.441779e-3
GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent	3.441779e-3
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	3.441779e-3
GO:0051788	response to misfolded protein	3.447703e-3
GO:0002707	negative regulation of lymphocyte mediated immunity	3.476544e-3
GO:0061009	common bile duct development	3.492523e-3
GO:0002067	glandular epithelial cell differentiation	3.570062e-3
GO:0010557	positive regulation of macromolecule biosynthetic process	3.579964e-3
GO:0015884	folic acid transport	3.627779e-3
GO:0018022	peptidyl-lysine methylation	3.629269e-3
GO:0021696	cerebellar cortex morphogenesis	3.659301e-3
GO:0046847	filopodium assembly	3.660411e-3
GO:0043966	histone H3 acetylation	3.742911e-3
GO:0055062	phosphate ion homeostasis	3.761436e-3
GO:0043276	anoikis	3.773477e-3
GO:0021569	rhombomere 3 development	3.786742e-3
GO:0050909	sensory perception of taste	3.811126e-3
GO:0060311	negative regulation of elastin catabolic process	3.816177e-3
GO:0060313	negative regulation of blood vessel remodeling	3.816177e-3
GO:0006780	uroporphyrinogen III biosynthetic process	3.816177e-3
GO:0010711	negative regulation of collagen catabolic process	3.816177e-3
GO:0010703	negative regulation of histolysis	3.816177e-3
GO:0009231	riboflavin biosynthetic process	3.816177e-3
GO:0043271	negative regulation of ion transport	3.824590e-3
GO:0045955	negative regulation of calcium ion-dependent exocytosis	3.983363e-3
GO:0045618	positive regulation of keratinocyte differentiation	3.983363e-3
GO:0045654	positive regulation of megakaryocyte differentiation	3.999127e-3
GO:0007096	regulation of exit from mitosis	4.010724e-3
GO:0097150	neuronal stem cell maintenance	4.016466e-3
GO:0042267	natural killer cell mediated cytotoxicity	4.049051e-3
GO:0072189	ureter development	4.086912e-3
GO:0060556	regulation of vitamin D biosynthetic process	4.088681e-3
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	4.099755e-3
GO:0003094	glomerular filtration	4.099755e-3
GO:0022027	interkinetic nuclear migration	4.132926e-3
GO:0048340	paraxial mesoderm morphogenesis	4.248031e-3
GO:0051150	regulation of smooth muscle cell differentiation	4.287078e-3
GO:0019227	neuronal action potential propagation	4.330436e-3
GO:0072079	nephron tubule formation	4.372405e-3
GO:0032796	uropod organization	4.394639e-3
GO:0032606	type I interferon production	4.394639e-3
GO:0032225	regulation of synaptic transmission, dopaminergic	4.450277e-3
GO:0030802	regulation of cyclic nucleotide biosynthetic process	4.474238e-3
GO:0021675	nerve development	4.476846e-3
GO:0061037	negative regulation of cartilage development	4.484531e-3
GO:0060391	positive regulation of SMAD protein import into nucleus	4.529247e-3
GO:0070265	necrotic cell death	4.570543e-3
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	4.602760e-3
GO:0035771	interleukin-4-mediated signaling pathway	4.605560e-3
GO:0031643	positive regulation of myelination	4.605560e-3
GO:0051693	actin filament capping	4.607835e-3
GO:0071731	response to nitric oxide	4.627841e-3
GO:0043921	modulation by host of viral transcription	4.641466e-3
GO:0009812	flavonoid metabolic process	4.649418e-3
GO:0031532	actin cytoskeleton reorganization	4.649598e-3
GO:0005993	trehalose catabolic process	4.666293e-3
GO:0048103	somatic stem cell division	4.667112e-3
GO:0060517	epithelial cell proliferation involved in prostatic bud elongation	4.692698e-3
GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis	4.692698e-3
GO:0060784	regulation of cell proliferation involved in tissue homeostasis	4.692698e-3
GO:0033147	negative regulation of estrogen receptor signaling pathway	4.692698e-3
GO:0003415	chondrocyte hypertrophy	4.692698e-3
GO:0019100	male germ-line sex determination	4.692698e-3
GO:0035622	intrahepatic bile duct development	4.692698e-3
GO:0010310	regulation of hydrogen peroxide metabolic process	4.707355e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0048705	skeletal system morphogenesis	7.100888e-13
GO:0048706	embryonic skeletal system development	9.044464e-12
GO:0070208	protein heterotrimerization	7.488448e-11
GO:0060346	bone trabecula formation	2.145213e-10
GO:0001957	intramembranous ossification	4.466494e-10
GO:2000195	negative regulation of female gonad development	1.184629e-9
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	1.975783e-9
GO:0034505	tooth mineralization	2.210740e-9
GO:0060539	diaphragm development	4.314570e-9
GO:0001958	endochondral ossification	9.476889e-9
GO:2000194	regulation of female gonad development	1.084766e-8
GO:0048384	retinoic acid receptor signaling pathway	1.170359e-8
GO:0001501	skeletal system development	1.505053e-8
GO:0060325	face morphogenesis	1.688051e-8
GO:0043588	skin development	1.743468e-8
GO:0061383	trabecula morphogenesis	2.227446e-8
GO:0060323	head morphogenesis	2.638552e-8
GO:0060343	trabecula formation	2.895506e-8
GO:0060457	negative regulation of digestive system process	3.365050e-8
GO:0015816	glycine transport	3.420549e-8
GO:0048704	embryonic skeletal system morphogenesis	6.360364e-8
GO:0072278	metanephric comma-shaped body morphogenesis	1.026267e-7
GO:0072284	metanephric S-shaped body morphogenesis	1.026267e-7
GO:2001076	positive regulation of metanephric ureteric bud development	1.103356e-7
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	1.103356e-7
GO:0007356	thorax and anterior abdomen determination	1.103356e-7
GO:0043589	skin morphogenesis	1.826565e-7
GO:0015804	neutral amino acid transport	2.093199e-7
GO:0051533	positive regulation of NFAT protein import into nucleus	2.129624e-7
GO:0008154	actin polymerization or depolymerization	2.434472e-7
GO:0071417	cellular response to organic nitrogen	2.799851e-7
GO:2000249	regulation of actin cytoskeleton reorganization	3.096292e-7
GO:0048298	positive regulation of isotype switching to IgA isotypes	3.459091e-7
GO:0071230	cellular response to amino acid stimulus	3.563686e-7
GO:0060350	endochondral bone morphogenesis	4.011034e-7
GO:0051291	protein heterooligomerization	4.332705e-7
GO:0032649	regulation of interferon-gamma production	4.508700e-7
GO:0071300	cellular response to retinoic acid	5.637407e-7
GO:0030199	collagen fibril organization	5.799170e-7
GO:0071299	cellular response to vitamin A	6.270716e-7
GO:0051216	cartilage development	6.590078e-7
GO:0045796	negative regulation of intestinal cholesterol absorption	6.774361e-7
GO:0010949	negative regulation of intestinal phytosterol absorption	6.774361e-7
GO:0061143	alveolar primary septum development	7.339181e-7
GO:0071418	cellular response to amine stimulus	1.082670e-6
GO:0071229	cellular response to acid	1.263193e-6
GO:0010171	body morphogenesis	1.505196e-6
GO:0007566	embryo implantation	1.640200e-6
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	2.642923e-6
GO:0070383	DNA cytosine deamination	4.210101e-6
GO:0010529	negative regulation of transposition	4.210101e-6
GO:0051293	establishment of spindle localization	4.300177e-6
GO:0002439	chronic inflammatory response to antigenic stimulus	4.653487e-6
GO:0032328	alanine transport	4.669025e-6
GO:0045624	positive regulation of T-helper cell differentiation	5.321199e-6
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	5.791622e-6
GO:0001830	trophectodermal cell fate commitment	6.235250e-6
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	6.558436e-6
GO:0002636	positive regulation of germinal center formation	6.721901e-6
GO:0030010	establishment of cell polarity	7.249592e-6
GO:0051220	cytoplasmic sequestering of protein	7.260962e-6
GO:0002149	hypochlorous acid biosynthetic process	7.637155e-6
GO:0042994	cytoplasmic sequestering of transcription factor	9.529365e-6
GO:0061048	negative regulation of branching involved in lung morphogenesis	1.011657e-5
GO:0045994	positive regulation of translational initiation by iron	1.011657e-5
GO:0034116	positive regulation of heterotypic cell-cell adhesion	1.011657e-5
GO:0002037	negative regulation of L-glutamate transport	1.011657e-5
GO:0030218	erythrocyte differentiation	1.056539e-5
GO:0060322	head development	1.060332e-5
GO:0030041	actin filament polymerization	1.147801e-5
GO:0031444	slow-twitch skeletal muscle fiber contraction	1.229137e-5
GO:0035621	ER to Golgi ceramide transport	1.399955e-5
GO:0001787	natural killer cell proliferation	1.439331e-5
GO:0060349	bone morphogenesis	1.606132e-5
GO:0000132	establishment of mitotic spindle orientation	1.622767e-5
GO:0045622	regulation of T-helper cell differentiation	1.670204e-5
GO:0001894	tissue homeostasis	1.675178e-5
GO:0010718	positive regulation of epithelial to mesenchymal transition	1.950580e-5
GO:0031581	hemidesmosome assembly	1.965056e-5
GO:0060324	face development	1.968542e-5
GO:0051135	positive regulation of NK T cell activation	2.013865e-5
GO:0060421	positive regulation of heart growth	2.013865e-5
GO:0048280	vesicle fusion with Golgi apparatus	2.020011e-5
GO:0045453	bone resorption	2.160763e-5
GO:0006366	transcription from RNA polymerase II promoter	2.214018e-5
GO:0072050	S-shaped body morphogenesis	2.293097e-5
GO:0072049	comma-shaped body morphogenesis	2.293097e-5
GO:0034589	hydroxyproline transport	2.298474e-5
GO:0015826	threonine transport	2.298474e-5
GO:0032534	regulation of microvillus assembly	2.714665e-5
GO:0060911	cardiac cell fate commitment	2.793100e-5
GO:0032774	RNA biosynthetic process	2.905145e-5
GO:0046849	bone remodeling	3.030927e-5
GO:0006351	transcription, DNA-dependent	3.175394e-5
GO:0072166	posterior mesonephric tubule development	3.323489e-5
GO:0002077	acrosome matrix dispersal	3.335654e-5
GO:0032329	serine transport	3.416011e-5
GO:0015808	L-alanine transport	3.416011e-5
GO:0046092	deoxycytidine metabolic process	3.440429e-5
GO:0050901	leukocyte tethering or rolling	3.528964e-5
GO:0040001	establishment of mitotic spindle localization	4.322880e-5
GO:0035307	positive regulation of protein dephosphorylation	4.411549e-5
GO:0045078	positive regulation of interferon-gamma biosynthetic process	4.421437e-5
GO:0045916	negative regulation of complement activation	4.796043e-5
GO:0034101	erythrocyte homeostasis	4.947001e-5
GO:0048535	lymph node development	4.998970e-5
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	5.070425e-5
GO:0051956	negative regulation of amino acid transport	5.142013e-5
GO:0048568	embryonic organ development	5.177715e-5
GO:0072015	glomerular visceral epithelial cell development	5.241054e-5
GO:0006297	nucleotide-excision repair, DNA gap filling	5.474819e-5
GO:0060010	Sertoli cell fate commitment	5.474819e-5
GO:0035306	positive regulation of dephosphorylation	5.537174e-5
GO:0048548	regulation of pinocytosis	5.636457e-5
GO:0045292	nuclear mRNA cis splicing, via spliceosome	5.872680e-5
GO:0070206	protein trimerization	6.264816e-5
GO:0048730	epidermis morphogenesis	6.304448e-5
GO:0021797	forebrain anterior/posterior pattern specification	6.389166e-5
GO:2000242	negative regulation of reproductive process	6.485460e-5
GO:0072125	negative regulation of glomerular mesangial cell proliferation	6.531786e-5
GO:0045948	positive regulation of translational initiation	6.564292e-5
GO:0010831	positive regulation of myotube differentiation	7.200281e-5
GO:0072124	regulation of glomerular mesangial cell proliferation	7.901993e-5
GO:0048871	multicellular organismal homeostasis	8.009530e-5
GO:0060351	cartilage development involved in endochondral bone morphogenesis	8.109063e-5
GO:0097026	dendritic cell dendrite assembly	8.308516e-5
GO:0032312	regulation of ARF GTPase activity	8.507802e-5
GO:0045071	negative regulation of viral genome replication	8.777143e-5
GO:2000465	regulation of glycogen (starch) synthase activity	8.805326e-5
GO:0007619	courtship behavior	9.156495e-5
GO:0006357	regulation of transcription from RNA polymerase II promoter	9.655748e-5
GO:0009891	positive regulation of biosynthetic process	1.050842e-4
GO:0048525	negative regulation of viral reproduction	1.054438e-4
GO:0031076	embryonic camera-type eye development	1.140917e-4
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	1.245359e-4
GO:0009589	detection of UV	1.245359e-4
GO:0003184	pulmonary valve morphogenesis	1.361681e-4
GO:0035802	adrenal cortex formation	1.530701e-4
GO:0002036	regulation of L-glutamate transport	1.542321e-4
GO:0060923	cardiac muscle cell fate commitment	1.612448e-4
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1.678311e-4
GO:0061205	paramesonephric duct development	1.725326e-4
GO:0051258	protein polymerization	1.791277e-4
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	1.860910e-4
GO:0031325	positive regulation of cellular metabolic process	1.896093e-4
GO:0045006	DNA deamination	1.917977e-4
GO:0010893	positive regulation of steroid biosynthetic process	1.952671e-4
GO:0048562	embryonic organ morphogenesis	2.055054e-4
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	2.241157e-4
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	2.243642e-4
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	2.287406e-4
GO:0016926	protein desumoylation	2.287406e-4
GO:0045627	positive regulation of T-helper 1 cell differentiation	2.320856e-4
GO:0001887	selenium compound metabolic process	2.437316e-4
GO:0097022	lymphocyte migration into lymph node	2.468834e-4
GO:0072610	interleukin-12 secretion	2.468834e-4
GO:0032754	positive regulation of interleukin-5 production	2.485751e-4
GO:0042843	D-xylose catabolic process	2.488269e-4
GO:0033979	box H/ACA snoRNA metabolic process	2.488269e-4
GO:0009972	cytidine deamination	2.489353e-4
GO:0060557	positive regulation of vitamin D biosynthetic process	2.537160e-4
GO:0034142	toll-like receptor 4 signaling pathway	2.558919e-4
GO:0015671	oxygen transport	2.635183e-4
GO:0001771	immunological synapse formation	2.635183e-4
GO:0009113	purine base biosynthetic process	2.677762e-4
GO:0071624	positive regulation of granulocyte chemotaxis	2.683256e-4
GO:0046628	positive regulation of insulin receptor signaling pathway	2.978778e-4
GO:0010940	positive regulation of necrotic cell death	3.082561e-4
GO:0040032	post-embryonic body morphogenesis	3.098182e-4
GO:0002426	immunoglobulin production in mucosal tissue	3.162673e-4
GO:0031328	positive regulation of cellular biosynthetic process	3.188056e-4
GO:0043966	histone H3 acetylation	3.427429e-4
GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein	3.532777e-4
GO:0032720	negative regulation of tumor necrosis factor production	3.553216e-4
GO:0046135	pyrimidine nucleoside catabolic process	3.638095e-4
GO:0001768	establishment of T cell polarity	3.638095e-4
GO:0010939	regulation of necrotic cell death	3.648495e-4
GO:0043973	histone H3-K4 acetylation	3.654522e-4
GO:0046985	positive regulation of hemoglobin biosynthetic process	3.654522e-4
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.654522e-4
GO:0002642	positive regulation of immunoglobulin biosynthetic process	3.654522e-4
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	3.654522e-4
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.654522e-4
GO:0033189	response to vitamin A	3.687199e-4
GO:0023019	signal transduction involved in regulation of gene expression	3.695191e-4
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	3.771455e-4
GO:0031323	regulation of cellular metabolic process	3.800166e-4
GO:0046889	positive regulation of lipid biosynthetic process	3.859118e-4
GO:0021871	forebrain regionalization	3.939156e-4
GO:0030261	chromosome condensation	3.999310e-4
GO:2000412	positive regulation of thymocyte migration	4.035753e-4
GO:0002518	lymphocyte chemotaxis across high endothelial venule	4.035753e-4
GO:0015811	L-cystine transport	4.092918e-4
GO:0002155	regulation of thyroid hormone mediated signaling pathway	4.092918e-4
GO:0048549	positive regulation of pinocytosis	4.214739e-4
GO:0045901	positive regulation of translational elongation	4.214739e-4
GO:0045905	positive regulation of translational termination	4.214739e-4
GO:0006452	translational frameshifting	4.214739e-4
GO:0034653	retinoic acid catabolic process	4.214739e-4
GO:0045625	regulation of T-helper 1 cell differentiation	4.454058e-4
GO:0060459	left lung development	4.559157e-4
GO:0031648	protein destabilization	4.653019e-4
GO:0006672	ceramide metabolic process	4.682747e-4
GO:0002679	respiratory burst involved in defense response	4.730234e-4
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	5.063061e-4
GO:2000143	negative regulation of transcription initiation, DNA-dependent	5.118634e-4
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	5.198939e-4
GO:0034114	regulation of heterotypic cell-cell adhesion	5.198939e-4
GO:0010467	gene expression	5.255375e-4
GO:0032736	positive regulation of interleukin-13 production	5.303030e-4
GO:0043353	enucleate erythrocyte differentiation	5.363009e-4
GO:0008050	female courtship behavior	5.833095e-4
GO:0042255	ribosome assembly	5.905562e-4
GO:0032753	positive regulation of interleukin-4 production	5.975972e-4
GO:0009893	positive regulation of metabolic process	6.013146e-4
GO:0009059	macromolecule biosynthetic process	6.044165e-4
GO:0032530	regulation of microvillus organization	6.227674e-4
GO:0007000	nucleolus organization	6.227674e-4
GO:0060348	bone development	6.614491e-4
GO:0006665	sphingolipid metabolic process	6.656729e-4
GO:0072240	metanephric DCT cell differentiation	6.696270e-4
GO:0072227	metanephric macula densa development	6.696270e-4
GO:0035441	cell migration involved in vasculogenesis	6.696270e-4
GO:0015825	L-serine transport	6.696270e-4
GO:0010557	positive regulation of macromolecule biosynthetic process	6.768985e-4
GO:0021819	layer formation in cerebral cortex	6.796775e-4
GO:0060578	superior vena cava morphogenesis	6.799269e-4
GO:0030259	lipid glycosylation	6.807622e-4
GO:0030970	retrograde protein transport, ER to cytosol	7.097278e-4
GO:0045925	positive regulation of female receptivity	7.097278e-4
GO:0001869	negative regulation of complement activation, lectin pathway	7.097278e-4
GO:0051084	'de novo' posttranslational protein folding	7.235319e-4
GO:0009887	organ morphogenesis	7.368893e-4
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	7.411669e-4
GO:0032516	positive regulation of phosphoprotein phosphatase activity	7.519061e-4
GO:0007565	female pregnancy	7.655241e-4
GO:0045072	regulation of interferon-gamma biosynthetic process	7.698571e-4
GO:0032964	collagen biosynthetic process	7.833495e-4
GO:0034645	cellular macromolecule biosynthetic process	7.989745e-4
GO:2000020	positive regulation of male gonad development	8.023564e-4
GO:0030325	adrenal gland development	8.170061e-4
GO:0035305	negative regulation of dephosphorylation	8.298146e-4
GO:0003009	skeletal muscle contraction	8.365358e-4
GO:0021796	cerebral cortex regionalization	8.368142e-4
GO:0046339	diacylglycerol metabolic process	8.517708e-4
GO:0000028	ribosomal small subunit assembly	8.878990e-4
GO:0000380	alternative nuclear mRNA splicing, via spliceosome	8.954061e-4
GO:0008360	regulation of cell shape	9.028723e-4
GO:0060555	induction of necroptosis by extracellular signals	9.136974e-4
GO:0021978	telencephalon regionalization	9.204531e-4
GO:0001955	blood vessel maturation	9.230225e-4
GO:0007403	glial cell fate determination	9.349145e-4
GO:0071295	cellular response to vitamin	9.438330e-4
GO:2000188	regulation of cholesterol homeostasis	9.747177e-4
GO:0080090	regulation of primary metabolic process	9.804581e-4
GO:0043088	regulation of Cdc42 GTPase activity	9.939667e-4
GO:0003382	epithelial cell morphogenesis	1.009696e-3
GO:0001709	cell fate determination	1.032958e-3
GO:0010724	regulation of definitive erythrocyte differentiation	1.052378e-3
GO:0072112	glomerular visceral epithelial cell differentiation	1.059954e-3
GO:0007354	zygotic determination of anterior/posterior axis, embryo	1.080385e-3
GO:0006184	GTP catabolic process	1.085962e-3
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	1.109527e-3
GO:0030042	actin filament depolymerization	1.132061e-3
GO:0045924	regulation of female receptivity	1.142429e-3
GO:0000413	protein peptidyl-prolyl isomerization	1.156827e-3
GO:0045869	negative regulation of retroviral genome replication	1.164682e-3
GO:0070869	heterochromatin formation involved in chromatin silencing	1.172572e-3
GO:0043585	nose morphogenesis	1.172572e-3
GO:0001555	oocyte growth	1.172572e-3
GO:0035435	phosphate ion transmembrane transport	1.172572e-3
GO:2000467	positive regulation of glycogen (starch) synthase activity	1.177476e-3
GO:0051532	regulation of NFAT protein import into nucleus	1.186316e-3
GO:0010034	response to acetate	1.187467e-3
GO:0001514	selenocysteine incorporation	1.187467e-3
GO:0010604	positive regulation of macromolecule metabolic process	1.234462e-3
GO:0045893	positive regulation of transcription, DNA-dependent	1.237498e-3
GO:0001503	ossification	1.256902e-3
GO:0007162	negative regulation of cell adhesion	1.257644e-3
GO:0008625	induction of apoptosis via death domain receptors	1.267798e-3
GO:0051798	positive regulation of hair follicle development	1.317465e-3
GO:0006517	protein deglycosylation	1.350943e-3
GO:0000027	ribosomal large subunit assembly	1.350943e-3
GO:2000018	regulation of male gonad development	1.358953e-3
GO:0045123	cellular extravasation	1.362170e-3
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	1.368735e-3
GO:0051171	regulation of nitrogen compound metabolic process	1.368910e-3
GO:0032515	negative regulation of phosphoprotein phosphatase activity	1.381640e-3
GO:0070684	seminal clot liquefaction	1.389828e-3
GO:0042941	D-alanine transport	1.389828e-3
GO:0019219	regulation of nucleobase-containing compound metabolic process	1.511996e-3
GO:0060231	mesenchymal to epithelial transition	1.531485e-3
GO:0046709	IDP catabolic process	1.539121e-3
GO:2000275	regulation of oxidative phosphorylation uncoupler activity	1.539121e-3
GO:0046032	ADP catabolic process	1.539121e-3
GO:0006449	regulation of translational termination	1.539121e-3
GO:2000189	positive regulation of cholesterol homeostasis	1.580738e-3
GO:0034504	protein localization to nucleus	1.614363e-3
GO:0051597	response to methylmercury	1.616396e-3
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1.629343e-3
GO:0003229	ventricular cardiac muscle tissue development	1.648507e-3
GO:0046519	sphingoid metabolic process	1.682257e-3
GO:0043558	regulation of translational initiation in response to stress	1.707031e-3
GO:0051205	protein insertion into membrane	1.710205e-3
GO:0060558	regulation of calcidiol 1-monooxygenase activity	1.714178e-3
GO:0043089	positive regulation of Cdc42 GTPase activity	1.726242e-3
GO:0043983	histone H4-K12 acetylation	1.729273e-3
GO:0008542	visual learning	1.758176e-3
GO:0051254	positive regulation of RNA metabolic process	1.774789e-3
GO:0006528	asparagine metabolic process	1.800463e-3
GO:0055010	ventricular cardiac muscle tissue morphogenesis	1.816103e-3
GO:0051253	negative regulation of RNA metabolic process	1.851718e-3
GO:0046341	CDP-diacylglycerol metabolic process	1.857322e-3
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	1.857322e-3
GO:0046039	GTP metabolic process	1.870151e-3
GO:0070831	basement membrane assembly	1.889463e-3
GO:0006927	transformed cell apoptosis	1.940436e-3
GO:0072348	sulfur compound transport	1.940436e-3
GO:0006678	glucosylceramide metabolic process	1.940436e-3
GO:0060244	negative regulation of cell proliferation involved in contact inhibition	1.965642e-3
GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.965642e-3
GO:0021513	spinal cord dorsal/ventral patterning	1.973909e-3
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	1.983237e-3
GO:0090218	positive regulation of lipid kinase activity	1.986490e-3
GO:0007044	cell-substrate junction assembly	2.000595e-3
GO:0007168	receptor guanylyl cyclase signaling pathway	2.011425e-3
GO:0032784	regulation of transcription elongation, DNA-dependent	2.037426e-3
GO:0070170	regulation of tooth mineralization	2.068866e-3
GO:0001963	synaptic transmission, dopaminergic	2.089529e-3
GO:0010717	regulation of epithelial to mesenchymal transition	2.124365e-3
GO:0090026	positive regulation of monocyte chemotaxis	2.143376e-3
GO:0018208	peptidyl-proline modification	2.144843e-3
GO:0045892	negative regulation of transcription, DNA-dependent	2.170685e-3
GO:0015824	proline transport	2.175295e-3
GO:0018393	internal peptidyl-lysine acetylation	2.238989e-3
GO:0060978	angiogenesis involved in coronary vascular morphogenesis	2.239862e-3
GO:0048596	embryonic camera-type eye morphogenesis	2.277017e-3
GO:0090280	positive regulation of calcium ion import	2.296356e-3
GO:0071316	cellular response to nicotine	2.296356e-3
GO:0001818	negative regulation of cytokine production	2.308044e-3
GO:0090307	spindle assembly involved in mitosis	2.353458e-3
GO:0042274	ribosomal small subunit biogenesis	2.452218e-3
GO:0051953	negative regulation of amine transport	2.529565e-3
GO:0035909	aorta morphogenesis	2.531375e-3
GO:0034134	toll-like receptor 2 signaling pathway	2.535289e-3
GO:0042732	D-xylose metabolic process	2.536954e-3
GO:0060900	embryonic camera-type eye formation	2.541795e-3
GO:0051797	regulation of hair follicle development	2.646258e-3
GO:0016070	RNA metabolic process	2.684299e-3
GO:0010288	response to lead ion	2.693039e-3
GO:0032526	response to retinoic acid	2.758303e-3
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	2.768923e-3
GO:0018394	peptidyl-lysine acetylation	2.809180e-3
GO:0048665	neuron fate specification	2.819203e-3
GO:0070646	protein modification by small protein removal	2.831687e-3
GO:0031125	rRNA 3'-end processing	2.834944e-3
GO:0071371	cellular response to gonadotropin stimulus	2.838744e-3
GO:0033233	regulation of protein sumoylation	2.871339e-3
GO:0035404	histone-serine phosphorylation	2.964843e-3
GO:0030853	negative regulation of granulocyte differentiation	2.985326e-3
GO:0071711	basement membrane organization	3.034624e-3
GO:0033091	positive regulation of immature T cell proliferation	3.034624e-3
GO:0034446	substrate adhesion-dependent cell spreading	3.076478e-3
GO:0006475	internal protein amino acid acetylation	3.145084e-3
GO:0042631	cellular response to water deprivation	3.161630e-3
GO:0046174	polyol catabolic process	3.182324e-3
GO:0071803	positive regulation of podosome assembly	3.182324e-3
GO:0002115	store-operated calcium entry	3.182324e-3
GO:0042363	fat-soluble vitamin catabolic process	3.182324e-3
GO:2000015	regulation of determination of dorsal identity	3.201989e-3
GO:0035372	protein localization to microtubule	3.201989e-3
GO:0006446	regulation of translational initiation	3.223489e-3
GO:0051173	positive regulation of nitrogen compound metabolic process	3.243645e-3
GO:0032656	regulation of interleukin-13 production	3.305187e-3
GO:0051382	kinetochore assembly	3.309066e-3
GO:0016048	detection of temperature stimulus	3.313652e-3
GO:0018205	peptidyl-lysine modification	3.349194e-3
GO:0032673	regulation of interleukin-4 production	3.359515e-3
GO:0045091	regulation of retroviral genome replication	3.363915e-3
GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	3.365777e-3
GO:0097107	postsynaptic density assembly	3.365777e-3
GO:0034421	post-translational protein acetylation	3.365777e-3
GO:0090007	regulation of mitotic anaphase	3.365777e-3
GO:0006473	protein acetylation	3.377684e-3
GO:0072075	metanephric mesenchyme development	3.390361e-3
GO:0006643	membrane lipid metabolic process	3.435075e-3
GO:0045628	regulation of T-helper 2 cell differentiation	3.441866e-3
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	3.445708e-3
GO:0021903	rostrocaudal neural tube patterning	3.451630e-3
GO:0006704	glucocorticoid biosynthetic process	3.505681e-3
GO:0016055	Wnt receptor signaling pathway	3.518447e-3
GO:0010661	positive regulation of muscle cell apoptosis	3.546075e-3
GO:0010558	negative regulation of macromolecule biosynthetic process	3.567651e-3
GO:0090273	regulation of somatostatin secretion	3.569024e-3
GO:0010560	positive regulation of glycoprotein biosynthetic process	3.576528e-3
GO:0006098	pentose-phosphate shunt	3.633210e-3
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	3.667107e-3
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.667107e-3
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	3.667107e-3
GO:0021905	forebrain-midbrain boundary formation	3.667107e-3
GO:0003322	pancreatic A cell development	3.667107e-3
GO:0009988	cell-cell recognition	3.685614e-3
GO:0035137	hindlimb morphogenesis	3.766735e-3
GO:0010556	regulation of macromolecule biosynthetic process	3.808229e-3
GO:0046513	ceramide biosynthetic process	3.837715e-3
GO:0007163	establishment or maintenance of cell polarity	3.880170e-3
GO:0001829	trophectodermal cell differentiation	3.939940e-3
GO:0048588	developmental cell growth	3.948090e-3
GO:0060591	chondroblast differentiation	3.959090e-3
GO:0006355	regulation of transcription, DNA-dependent	3.967008e-3
GO:0010189	vitamin E biosynthetic process	3.971769e-3
GO:0007285	primary spermatocyte growth	3.971769e-3
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	4.025457e-3
GO:0031670	cellular response to nutrient	4.139950e-3
GO:0031507	heterochromatin formation	4.159427e-3
GO:0046330	positive regulation of JNK cascade	4.181380e-3
GO:0090169	regulation of spindle assembly	4.187352e-3
GO:0090234	regulation of kinetochore assembly	4.187352e-3
GO:0033345	asparagine catabolic process via L-aspartate	4.187352e-3
GO:0006975	DNA damage induced protein phosphorylation	4.187352e-3
GO:0003056	regulation of vascular smooth muscle contraction	4.187352e-3
GO:0007042	lysosomal lumen acidification	4.256199e-3
GO:0002649	regulation of tolerance induction to self antigen	4.256199e-3
GO:0060070	canonical Wnt receptor signaling pathway	4.265363e-3
GO:0060263	regulation of respiratory burst	4.278098e-3
GO:0030730	sequestering of triglyceride	4.286165e-3
GO:0010424	DNA methylation on cytosine within a CG sequence	4.286165e-3
GO:0021511	spinal cord patterning	4.340574e-3
GO:0072233	metanephric thick ascending limb development	4.423201e-3
GO:0072218	metanephric ascending thin limb development	4.423201e-3
GO:0006188	IMP biosynthetic process	4.423201e-3
GO:0051546	keratinocyte migration	4.502106e-3
GO:0071312	cellular response to alkaloid	4.618146e-3
GO:0090031	positive regulation of steroid hormone biosynthetic process	4.659242e-3
GO:0046637	regulation of alpha-beta T cell differentiation	4.688077e-3
GO:0033235	positive regulation of protein sumoylation	4.700615e-3
GO:0032786	positive regulation of transcription elongation, DNA-dependent	4.700615e-3
GO:0031652	positive regulation of heat generation	4.714823e-3
GO:0060460	left lung morphogenesis	4.719724e-3
GO:0051383	kinetochore organization	4.719724e-3
GO:0034441	plasma lipoprotein particle oxidation	4.719724e-3
GO:0046600	negative regulation of centriole replication	4.719724e-3
GO:0048008	platelet-derived growth factor receptor signaling pathway	4.765375e-3
GO:0006414	translational elongation	4.765375e-3
GO:0030522	intracellular receptor mediated signaling pathway	4.814055e-3
GO:0021799	cerebral cortex radially oriented cell migration	4.863274e-3
GO:0009952	anterior/posterior pattern specification	4.942592e-3
GO:0035518	histone H2A monoubiquitination	4.961831e-3
GO:0072210	metanephric nephron development	5.015977e-3
GO:0045080	positive regulation of chemokine biosynthetic process	5.026783e-3
GO:0030317	sperm motility	5.038910e-3
GO:0008544	epidermis development	5.089209e-3
GO:0060180	female mating behavior	5.106212e-3
GO:0060249	anatomical structure homeostasis	5.201515e-3
GO:0031643	positive regulation of myelination	5.218505e-3
GO:0044249	cellular biosynthetic process	5.223835e-3
GO:0045073	regulation of chemokine biosynthetic process	5.230576e-3
GO:0021764	amygdala development	5.302863e-3
GO:0048284	organelle fusion	5.388570e-3
GO:0009058	biosynthetic process	5.394994e-3
GO:0051323	metaphase	5.408648e-3
GO:0032318	regulation of Ras GTPase activity	5.455722e-3
GO:0019693	ribose phosphate metabolic process	5.487337e-3
GO:0021570	rhombomere 4 development	5.599494e-3
GO:0035695	mitochondrion degradation by induced vacuole formation	5.599494e-3
GO:0045630	positive regulation of T-helper 2 cell differentiation	5.651009e-3
GO:0015012	heparan sulfate proteoglycan biosynthetic process	5.652755e-3
GO:2000193	positive regulation of fatty acid transport	5.652755e-3
GO:0006448	regulation of translational elongation	5.652755e-3
GO:0035752	lysosomal lumen pH elevation	5.713028e-3
GO:0001575	globoside metabolic process	5.713028e-3
GO:0000046	autophagic vacuole fusion	5.713028e-3
GO:0007266	Rho protein signal transduction	5.745502e-3
GO:0046670	positive regulation of retinal cell programmed cell death	5.875836e-3
GO:0051684	maintenance of Golgi location	5.875836e-3
GO:0002525	acute inflammatory response to non-antigenic stimulus	5.875836e-3
GO:0051668	localization within membrane	5.901119e-3
GO:0035304	regulation of protein dephosphorylation	5.901119e-3
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	5.986225e-3
GO:0060577	pulmonary vein morphogenesis	6.006255e-3
GO:0019405	alditol catabolic process	6.006255e-3
GO:0035694	mitochondrial protein catabolic process	6.006255e-3
GO:0035767	endothelial cell chemotaxis	6.076171e-3
GO:0048048	embryonic eye morphogenesis	6.082452e-3
GO:0006687	glycosphingolipid metabolic process	6.116438e-3
GO:0006102	isocitrate metabolic process	6.121042e-3
GO:0031622	positive regulation of fever generation	6.124545e-3
GO:0021960	anterior commissure morphogenesis	6.124545e-3
GO:0071480	cellular response to gamma radiation	6.133629e-3
GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	6.157917e-3
GO:0031326	regulation of cellular biosynthetic process	6.196276e-3
GO:0006144	purine base metabolic process	6.366133e-3
GO:0010629	negative regulation of gene expression	6.463662e-3
GO:0046427	positive regulation of JAK-STAT cascade	6.472805e-3
GO:0051252	regulation of RNA metabolic process	6.685029e-3
GO:0009889	regulation of biosynthetic process	6.732908e-3
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	6.742922e-3
GO:0035993	deltoid tuberosity development	6.749247e-3
GO:0007091	mitotic metaphase/anaphase transition	6.749247e-3
GO:0006681	galactosylceramide metabolic process	6.749247e-3