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MCL coexpression mm9:887: Difference between revisions

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{{MCL_coexpression_mm9
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secretion;0.0189057921069221;16534!GO:0050714;positive regulation of protein secretion;0.0189057921069221;16534!GO:0051047;positive regulation of secretion;0.0189057921069221;16534!GO:0015269;calcium-activated potassium channel activity;0.0189057921069221;16534!GO:0007589;fluid secretion;0.0189057921069221;16534!GO:0022839;ion gated channel activity;0.0189057921069221;16534!GO:0022600;digestive system process;0.0189057921069221;16534!GO:0050708;regulation of protein secretion;0.0189057921069221;16534!GO:0005227;calcium activated cation channel activity;0.0189057921069221;16534!GO:0009306;protein 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}}

Latest revision as of 16:03, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr11:112572664..112572681,-p1@BC006965
Mm9::chr11:112572783..112572793,-p2@ENSMUST00000142413
Mm9::chr12:77648835..77648861,-p1@uc007nyl.1
Mm9::chr5:66536984..66536985,-p@chr5:66536984..66536985
-
Mm9::chr5:66542145..66542199,-p3@Rbm47
Mm9::chr7:148646974..148647000,+p5@Efcab4a
Mm9::chr7:148647004..148647036,+p1@Efcab4a
Mm9::chr7:25155485..25155539,+p4@Kcnn4


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0046541saliva secretion0.0189057921069221
GO:0050714positive regulation of protein secretion0.0189057921069221
GO:0051047positive regulation of secretion0.0189057921069221
GO:0015269calcium-activated potassium channel activity0.0189057921069221
GO:0007589fluid secretion0.0189057921069221
GO:0022839ion gated channel activity0.0189057921069221
GO:0022600digestive system process0.0189057921069221
GO:0050708regulation of protein secretion0.0189057921069221
GO:0005227calcium activated cation channel activity0.0189057921069221
GO:0009306protein secretion0.0364292092115519
GO:0007586digestion0.044132415641375



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
epithelial bud3.94e-0817
thoracic cavity element6.42e-0717
thoracic segment organ6.42e-0717
thoracic cavity6.42e-0717
thoracic segment of trunk6.42e-0717
respiratory primordium6.42e-0717
endoderm of foregut6.42e-0717


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.400153
MA0004.10.434673
MA0006.10.747445
MA0007.10.419994
MA0009.10.870101
MA0014.10.0611475
MA0017.10.296816
MA0019.11.64517
MA0024.10.826339
MA0025.11.10341
MA0027.12.51754
MA0028.10.281528
MA0029.10.804619
MA0030.10.811181
MA0031.10.775627
MA0038.10.577528
MA0040.10.882616
MA0041.10.360875
MA0042.10.348174
MA0043.10.966833
MA0046.10.906029
MA0048.10.102483
MA0050.10.472794
MA0051.10.586414
MA0052.10.890676
MA0055.10.117901
MA0056.10
MA0057.10.643187
MA0058.10.341628
MA0059.10.353484
MA0060.10.197678
MA0061.10.638933
MA0063.10
MA0066.10.566617
MA0067.11.21448
MA0068.10.0965831
MA0069.10.891016
MA0070.10.881319
MA0071.10.471969
MA0072.10.872842
MA0073.10.0449725
MA0074.10.531046
MA0076.10.315013
MA0077.10.851175
MA0078.10.61926
MA0081.10.375851
MA0083.10.96604
MA0084.11.54225
MA0087.10.922929
MA0088.10.49616
MA0089.10
MA0090.10.401197
MA0091.10.447561
MA0092.10.401504
MA0093.10.289361
MA0095.10
MA0098.10
MA0100.10.519598
MA0101.10.362124
MA0103.10.307078
MA0105.10.823589
MA0106.10.626997
MA0107.10.301222
MA0108.20.710846
MA0109.10
MA0111.10.415012
MA0113.10.598933
MA0114.10.222763
MA0115.10.969632
MA0116.10.27152
MA0117.10.937363
MA0119.10.951747
MA0122.10.957212
MA0124.11.16127
MA0125.11.0872
MA0130.10
MA0131.10.683521
MA0132.10
MA0133.10
MA0135.11.00325
MA0136.10.550755
MA0139.10.169849
MA0140.10.519484
MA0141.10.325895
MA0142.10.761136
MA0143.10.615203
MA0144.10.640537
MA0145.10.900473
MA0146.10.0169049
MA0147.10.236889
MA0148.10.450593
MA0149.10.367458
MA0062.20.137653
MA0035.20.524137
MA0039.20.254826
MA0138.21.61926
MA0002.20.988033
MA0137.21.55649
MA0104.20.18504
MA0047.20.576767
MA0112.20.2464
MA0065.20.247168
MA0150.10.419883
MA0151.10
MA0152.10.576873
MA0153.11.01988
MA0154.10.330759
MA0155.12.00864
MA0156.10.314185
MA0157.10.729116
MA0158.10
MA0159.10.246253
MA0160.10.453546
MA0161.10
MA0162.10.0211019
MA0163.10.408151
MA0164.10.551114
MA0080.20.302064
MA0018.20.560731
MA0099.20.669311
MA0079.20.118858
MA0102.21.59466
MA0258.10.210437
MA0259.10.227035
MA0442.10
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