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MCL coexpression mm9:1009: Difference between revisions

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{{MCL_coexpression_mm9
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inhibitor activity;0.00813475747043468;12380!GO:0001783;B cell apoptosis;0.00813475747043468;103213!GO:0030091;protein repair;0.00813475747043468;320183!GO:0000318;protein-methionine-R-oxide reductase activity;0.00813475747043468;320183!GO:0016671;oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor;0.0173493954035186;320183!GO:0048305;immunoglobulin secretion;0.0198762477607476;103213!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0309606958326231;320183!GO:0004869;cysteine protease inhibitor activity;0.036101018137574;12380!GO:0009306;protein secretion;0.036101018137574;103213!GO:0002377;immunoglobulin production;0.0393613436801453;103213!GO:0002440;production of molecular mediator of immune 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|gostat_on_MCL_coexpression=GO:0030161;calpain inhibitor activity;0.00813475747043468;12380!GO:0001783;B cell apoptosis;0.00813475747043468;103213!GO:0030091;protein repair;0.00813475747043468;320183!GO:0000318;protein-methionine-R-oxide reductase activity;0.00813475747043468;320183!GO:0016671;oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor;0.0173493954035186;320183!GO:0048305;immunoglobulin secretion;0.0198762477607476;103213!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0309606958326231;320183!GO:0004869;cysteine protease inhibitor activity;0.036101018137574;12380!GO:0009306;protein secretion;0.036101018137574;103213!GO:0002377;immunoglobulin production;0.0393613436801453;103213!GO:0002440;production of molecular mediator of immune response;0.0393613436801453;103213!
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|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0004535!6.65e-10!23;UBERON:0001009!6.65e-10!23;UBERON:0004872!1.20e-08!33;UBERON:0007100!7.45e-07!18;UBERON:0000948!7.45e-07!18;UBERON:0005498!7.45e-07!18;UBERON:0004140!7.45e-07!18;UBERON:0009881!7.45e-07!18;UBERON:0004141!7.45e-07!18;UBERON:0003084!7.45e-07!18;UBERON:0007005!7.45e-07!18;UBERON:0004139!7.45e-07!18;UBERON:0004291!7.45e-07!18;UBERON:0005156!7.52e-07!26;UBERON:0000990!7.52e-07!26
|tfbs_overrepresentation_for_novel_motifs=0.438063,1.9469,0.411716,0.480627,0.299217,0.495263,0.587291,0.206208,1.15776,2.91464,0.542749,0.575086,0.206435,0.599731,0.847296,0,0.795315,0.291368,2.38602,0.361892,0.374752,0.586604,0.598814,0.29769,0.419327,1.51917,0.184473,0.516511,0.344372,0.145661,0.50223,0.897561,0.289148,1.53598,0.316253,0.0235321,0.279977,0.57142,0.258564,0.230656,0.295233,0.507468,0.54842,0.317766,0.515031,0.469348,1.70029,0.532496,0.478447,0.347313,0.777641,0.654933,0.431711,1.04034,1.0579,0.606984,0.937475,0.56214,0.522357,0.604914,0.877332,0.664501,0.642748,0.766235,0.618279,0.807219,1.19497,1.54543,0.872612,1.39786,1.01778,0.21183,1.02583,1.09164,0.507615,0.159969,0.963958,0.703064,0.859987,0.378988,0.212973,0.812889,0.663039,1.09903,0.975495,1.84334,0.164297,0.145788,0.719558,1.70793,1.26498,0.980512,0.910485,0.823238,2.82046,0.237542,0.203879,0.913319,2.85504,0.79664,0.280055,0.897279,1.02279,0.778243,0.777175,0.507021,0.837607,0.528416,0.998363,0.376549,0.430942,1.02459,0.380122,0.547992,1.27206,0.796976,1.12953,0.484437,0.796633,0.276329,1.09707,0.745011,0.629509,0.702145,1.32639,0.863723,0.595563,0.903645,1.19345,1.5026,1.00568,0.473246,1.16374,0.620831,1.29374,0.0806013,1.13474,0.508896,1.24438,2.07659,1.67603,1.19971,0.641722,0.908128,0.770616,0.507927,0.717753,2.03691,0.448938,0.300961,0.452587,0.927167,1.04192,0.243291,0.619892,1.12411,0.655955,0.874089,1.11101,0.446272,1.25393,0.974632,0.864173,0.428662,0.767269,0.612377,0.278874,0.573477,1.03935
|tfbs_overrepresentation_jaspar=MA0003.1;4.19152,MA0004.1;0.481116,MA0006.1;0.837454,MA0007.1;0.465969,MA0009.1;0.92425,MA0014.1;3.41543,MA0017.1;0.337808,MA0019.1;0.740036,MA0024.1;0.880057,MA0025.1;1.15921,MA0027.1;2.57545,MA0028.1;0.321735,MA0029.1;0.858105,MA0030.1;0.864739,MA0031.1;0.828781,MA0038.1;0.62758,MA0040.1;0.936879,MA0041.1;0.404721,MA0042.1;0.391504,MA0043.1;1.02178,MA0046.1;0.960497,MA0048.1;0.128106,MA0050.1;0.520357,MA0051.1;0.636645,MA0052.1;0.945011,MA0055.1;0.0406078,MA0056.1;0,MA0057.1;0.756125,MA0058.1;0.384683,MA0059.1;0.397033,MA0060.1;0.232592,MA0061.1;2.86794,MA0063.1;0,MA0066.1;0.616444,MA0067.1;1.27078,MA0068.1;0.771749,MA0069.1;0.945354,MA0070.1;0.93557,MA0071.1;0.519509,MA0072.1;0.927016,MA0073.1;4.19963e-05,MA0074.1;0.580087,MA0076.1;0.356883,MA0077.1;0.905143,MA0078.1;0.670113,MA0081.1;0.420276,MA0083.1;1.02098,MA0084.1;1.59945,MA0087.1;0.977537,MA0088.1;1.49527,MA0089.1;0,MA0090.1;1.1347,MA0091.1;0.494398,MA0092.1;0.446857,MA0093.1;0.329976,MA0095.1;0,MA0098.1;0,MA0100.1;0.568369,MA0101.1;2.76091,MA0103.1;0.920496,MA0105.1;0.162418,MA0106.1;1.62423,MA0107.1;4.38636,MA0108.2;0.763162,MA0109.1;0,MA0111.1;0.460823,MA0113.1;0.649407,MA0114.1;0.259463,MA0115.1;1.0246,MA0116.1;0.311187,MA0117.1;0.992087,MA0119.1;0.40661,MA0122.1;1.01209,MA0124.1;1.21735,MA0125.1;1.14291,MA0130.1;0,MA0131.1;0.735438,MA0132.1;0,MA0133.1;0,MA0135.1;1.05845,MA0136.1;0.600242,MA0139.1;0.202522,MA0140.1;0.568252,MA0141.1;0.368264,MA0142.1;0.814115,MA0143.1;0.665982,MA0144.1;0.262477,MA0145.1;1.05551,MA0146.1;0.792204,MA0147.1;0.753844,MA0148.1;0.49752,MA0149.1;0.411562,MA0062.2;0.967192,MA0035.2;0.573016,MA0039.2;0.0478878,MA0138.2;0.727395,MA0002.2;0.205289,MA0137.2;0.365364,MA0104.2;0.624968,MA0047.2;0.626803,MA0112.2;4.21276,MA0065.2;0.305574,MA0150.1;0.465855,MA0151.1;0,MA0152.1;0.626912,MA0153.1;1.07519,MA0154.1;0.792589,MA0155.1;2.2767,MA0156.1;0.936991,MA0157.1;0.781683,MA0158.1;0,MA0159.1;0.284457,MA0160.1;0.50056,MA0161.1;0,MA0162.1;0.302441,MA0163.1;0.0280055,MA0164.1;0.600609,MA0080.2;0.343316,MA0018.2;0.610433,MA0099.2;0.721008,MA0079.2;0.432076,MA0102.2;1.65195,MA0258.1;1.27611,MA0259.1;0.26402,MA0442.1;0
}}

Latest revision as of 16:15, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr10:120336020..120336044,-p2@Msrb3
Mm9::chr10:120336045..120336067,-p3@Msrb3
Mm9::chr10:120336082..120336093,-p7@Msrb3
Mm9::chr10:120336107..120336118,-p5@Msrb3
Mm9::chr10:126632296..126632354,+p1@F420014N23Rik
Mm9::chr10:39332941..39332960,+p2@Traf3ip2
Mm9::chr13:74946300..74946335,-p9@Cast


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0030161calpain inhibitor activity0.00813475747043468
GO:0001783B cell apoptosis0.00813475747043468
GO:0030091protein repair0.00813475747043468
GO:0000318protein-methionine-R-oxide reductase activity0.00813475747043468
GO:0016671oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor0.0173493954035186
GO:0048305immunoglobulin secretion0.0198762477607476
GO:0016667oxidoreductase activity, acting on sulfur group of donors0.0309606958326231
GO:0004869cysteine protease inhibitor activity0.036101018137574
GO:0009306protein secretion0.036101018137574
GO:0002377immunoglobulin production0.0393613436801453
GO:0002440production of molecular mediator of immune response0.0393613436801453



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.14.19152
MA0004.10.481116
MA0006.10.837454
MA0007.10.465969
MA0009.10.92425
MA0014.13.41543
MA0017.10.337808
MA0019.10.740036
MA0024.10.880057
MA0025.11.15921
MA0027.12.57545
MA0028.10.321735
MA0029.10.858105
MA0030.10.864739
MA0031.10.828781
MA0038.10.62758
MA0040.10.936879
MA0041.10.404721
MA0042.10.391504
MA0043.11.02178
MA0046.10.960497
MA0048.10.128106
MA0050.10.520357
MA0051.10.636645
MA0052.10.945011
MA0055.10.0406078
MA0056.10
MA0057.10.756125
MA0058.10.384683
MA0059.10.397033
MA0060.10.232592
MA0061.12.86794
MA0063.10
MA0066.10.616444
MA0067.11.27078
MA0068.10.771749
MA0069.10.945354
MA0070.10.93557
MA0071.10.519509
MA0072.10.927016
MA0073.14.19963e-05
MA0074.10.580087
MA0076.10.356883
MA0077.10.905143
MA0078.10.670113
MA0081.10.420276
MA0083.11.02098
MA0084.11.59945
MA0087.10.977537
MA0088.11.49527
MA0089.10
MA0090.11.1347
MA0091.10.494398
MA0092.10.446857
MA0093.10.329976
MA0095.10
MA0098.10
MA0100.10.568369
MA0101.12.76091
MA0103.10.920496
MA0105.10.162418
MA0106.11.62423
MA0107.14.38636
MA0108.20.763162
MA0109.10
MA0111.10.460823
MA0113.10.649407
MA0114.10.259463
MA0115.11.0246
MA0116.10.311187
MA0117.10.992087
MA0119.10.40661
MA0122.11.01209
MA0124.11.21735
MA0125.11.14291
MA0130.10
MA0131.10.735438
MA0132.10
MA0133.10
MA0135.11.05845
MA0136.10.600242
MA0139.10.202522
MA0140.10.568252
MA0141.10.368264
MA0142.10.814115
MA0143.10.665982
MA0144.10.262477
MA0145.11.05551
MA0146.10.792204
MA0147.10.753844
MA0148.10.49752
MA0149.10.411562
MA0062.20.967192
MA0035.20.573016
MA0039.20.0478878
MA0138.20.727395
MA0002.20.205289
MA0137.20.365364
MA0104.20.624968
MA0047.20.626803
MA0112.24.21276
MA0065.20.305574
MA0150.10.465855
MA0151.10
MA0152.10.626912
MA0153.11.07519
MA0154.10.792589
MA0155.12.2767
MA0156.10.936991
MA0157.10.781683
MA0158.10
MA0159.10.284457
MA0160.10.50056
MA0161.10
MA0162.10.302441
MA0163.10.0280055
MA0164.10.600609
MA0080.20.343316
MA0018.20.610433
MA0099.20.721008
MA0079.20.432076
MA0102.21.65195
MA0258.11.27611
MA0259.10.26402
MA0442.10
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