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MCL coexpression mm9:1326: Difference between revisions

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{{MCL_coexpression_mm9
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|ontology_enrichment_celltype=CL:0000066!6.09e-08!25
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000160!1.27e-15!31;UBERON:0005409!1.85e-13!47;UBERON:0004119!2.17e-13!118;UBERON:0000925!2.17e-13!118;UBERON:0006595!2.17e-13!118;UBERON:0001007!8.63e-13!116;UBERON:0001555!8.63e-13!116;UBERON:0007026!8.63e-13!116;UBERON:0004921!6.77e-12!114;UBERON:0000344!1.82e-09!15;UBERON:0001242!2.01e-08!13;UBERON:0000060!2.01e-08!13;UBERON:0001262!2.01e-08!13;UBERON:0004786!2.01e-08!13;UBERON:0005256!6.03e-07!45
|tfbs_overrepresentation_for_novel_motifs=0.491922,0.473747,0.464605,1.32583,0.346849,0.550971,0.645383,0.691572,0.7141,0.0835344,0.599767,0.632897,0.247704,0.6581,0.364314,0,0.856992,0.338549,0.232269,0.442204,0.426133,0.35122,0.657163,0.345236,0.472505,0.686615,0.223823,0.572827,0.394364,0.181062,0.558142,0.960397,0.336199,0.204204,0.364821,0.607065,0.326478,0.629145,0.303703,0.27383,0.342638,0.56353,0.671603,0.366415,0.161543,0.524258,0.77511,0.589246,2.04755,0.397446,0.839084,0.714419,0.517905,1.10437,1.12205,0.66551,0.406788,0.619643,0.21472,0.663395,0.939962,0.724164,0.269393,0.827522,0.677043,0.869046,1.2599,1.61148,0.935192,1.46355,0.444872,0.70565,1.77235,1.156,0.208101,0.19692,0.204132,1.80128,0.922432,1.10012,2.01946,0.874787,0.722675,1.25583,1.03903,0.439832,0.220054,0.181203,0.780154,1.77427,1.33021,1.04409,0.973447,0.9304,2.2472,0.281222,0.685716,0.976308,0.775372,0.160254,0.326561,0.960112,1.08669,0.839694,0.838613,0.563071,0.8998,1.42973,0.435642,0.428007,1.21641,1.0885,0.431734,0.605144,1.33732,0.90315,0.0704207,0.53982,0.858327,0.862623,1.16147,0.805995,0.688501,0.762461,1.39185,0.926209,0.65384,0.966541,1.25836,0.937314,1.06946,0.52828,1.2285,0.679647,1.35909,0.106956,2.16332,0.564999,1.30952,2.14327,1.74232,1.26465,0.700956,0.971067,0.831964,0.564002,0.778321,2.10357,0.503174,0.348692,1.63376,0.325363,1.10596,0.783181,0.678689,1.18867,1.70209,0.376898,0.48935,0.500417,1.31911,1.03816,2.1365,0.482185,0.82857,0.671017,0.86867,0.63125,0.30995
}}

Latest revision as of 16:45, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr12:55757483..55757504,-p1@1110002B05Rik
Mm9::chr5:104450798..104450815,-p2@Hsd17b11
Mm9::chr5:104450818..104450884,-p1@Hsd17b11
Mm9::chr5:8996618..8996632,-p2@Crot
Mm9::chr5:8996642..8996647,-p9@Crot
Mm9::chr5:8996655..8996667,-p5@Crot


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0008458carnitine O-octanoyltransferase activity0.0025749191913658
GO:0016415octanoyltransferase activity0.0025749191913658
GO:0016414O-octanoyltransferase activity0.0025749191913658
GO:0015908fatty acid transport0.00926716990639254
GO:0016406carnitine O-acyltransferase activity0.00926716990639254
GO:0004303estradiol 17-beta-dehydrogenase activity0.0102957270702699
GO:0044255cellular lipid metabolic process0.0151652090407481
GO:0006629lipid metabolic process0.0175099004677222
GO:0016229steroid dehydrogenase activity0.0180046905529867
GO:0008374O-acyltransferase activity0.0231374707154451
GO:0006694steroid biosynthetic process0.0474457324366066
GO:0006869lipid transport0.0474457324366066
GO:0042579microbody0.0483245373075855
GO:0005777peroxisome0.0483245373075855



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
epithelial cell6.09e-0825

Uber Anatomy
Ontology termp-valuen
intestine1.27e-1531
gastrointestinal system1.85e-1347
endoderm-derived structure2.17e-13118
endoderm2.17e-13118
presumptive endoderm2.17e-13118
digestive system8.63e-13116
digestive tract8.63e-13116
primitive gut8.63e-13116
subdivision of digestive tract6.77e-12114
mucosa1.82e-0915
intestinal mucosa2.01e-0813
anatomical wall2.01e-0813
wall of intestine2.01e-0813
gastrointestinal system mucosa2.01e-0813
trunk mesenchyme6.03e-0745


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.39154
MA0004.10.536396
MA0006.10.945134
MA0007.10.52077
MA0009.10.987341
MA0014.10.304529
MA0017.10.387481
MA0019.10.800946
MA0024.10.942716
MA0025.11.22395
MA0027.12.64231
MA0028.11.72321
MA0029.10.920529
MA0030.10.927235
MA0031.10.890871
MA0038.10.686534
MA0040.11.00009
MA0041.10.457338
MA0042.11.12834
MA0043.11.08567
MA0046.11.02391
MA0048.10.161427
MA0050.10.57678
MA0051.10.695779
MA0052.11.00829
MA0055.11.22706
MA0056.10
MA0057.10.149949
MA0058.10.436487
MA0059.10.449345
MA0060.13.87015
MA0061.10.307097
MA0063.10
MA0066.10.675169
MA0067.11.33603
MA0068.10.153907
MA0069.11.00864
MA0070.10.998765
MA0071.10.575909
MA0072.10.990133
MA0073.10.00140584
MA0074.10.638014
MA0076.11.04996
MA0077.10.968053
MA0078.10.729877
MA0081.10.473489
MA0083.11.08487
MA0084.11.66561
MA0087.11.04109
MA0088.10.725434
MA0089.10
MA0090.10.500693
MA0091.11.3559
MA0092.10.501022
MA0093.10.379257
MA0095.10
MA0098.10
MA0100.10.626021
MA0101.10.458688
MA0103.10.398766
MA0105.10.199622
MA0106.10.737893
MA0107.10.392331
MA0108.20.824407
MA0109.10
MA0111.10.515457
MA0113.10.708789
MA0114.10.304661
MA0115.11.08851
MA0116.10.359483
MA0117.11.05576
MA0119.10.459301
MA0122.11.07591
MA0124.11.28237
MA0125.11.20757
MA0130.10
MA0131.10.796279
MA0132.10
MA0133.10
MA0135.11.1226
MA0136.10.658622
MA0139.10.243463
MA0140.12.57126
MA0141.10.419361
MA0142.10.876028
MA0143.10.725672
MA0144.10.307873
MA0145.10.761789
MA0146.10.153598
MA0147.10.320675
MA0148.10.553294
MA0149.10.464445
MA0062.20.204999
MA0035.20.630778
MA0039.20.0271858
MA0138.20.788113
MA0002.20.246463
MA0137.20.416331
MA0104.20.261255
MA0047.20.685741
MA0112.20.37938
MA0065.20.380324
MA0150.10.520653
MA0151.10
MA0152.10.685852
MA0153.11.13945
MA0154.10.933846
MA0155.10.132921
MA0156.10.406559
MA0157.10.843181
MA0158.10
MA0159.10.331229
MA0160.10.556423
MA0161.10
MA0162.10.176524
MA0163.10.372305
MA0164.10.658997
MA0080.20.393257
MA0018.20.669032
MA0099.20.781628
MA0079.20.0520572
MA0102.21.7182
MA0258.10.290587
MA0259.10.309517
MA0442.10
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