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MCL coexpression mm9:2865: Difference between revisions

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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0016242;negative regulation of macroautophagy;0.0156759784556345;76482!GO:0016241;regulation of macroautophagy;0.0156759784556345;76482!GO:0033344;cholesterol efflux;0.0156759784556345;76482!GO:0008158;hedgehog receptor activity;0.0156759784556345;76482!GO:0007041;lysosomal transport;0.0156759784556345;76482!GO:0008206;bile acid metabolic process;0.0156759784556345;76482!GO:0016236;macroautophagy;0.0156759784556345;76482!GO:0030301;cholesterol transport;0.0156759784556345;76482!GO:0015918;sterol transport;0.0156759784556345;76482!GO:0007034;vacuolar transport;0.0156759784556345;76482!GO:0042632;cholesterol homeostasis;0.0156759784556345;76482!GO:0055088;lipid homeostasis;0.0156759784556345;76482!GO:0055092;sterol homeostasis;0.0156759784556345;76482!GO:0006914;autophagy;0.0196872959981344;76482!}}
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Latest revision as of 19:12, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr13:59924433..59924504,-p1@Zcchc6
Mm9::chr18:12327220..12327300,+p1@3110002H16Rik
Mm9::chr4:10934688..10934781,-p1@Plekhf2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0016242negative regulation of macroautophagy0.0156759784556345
GO:0016241regulation of macroautophagy0.0156759784556345
GO:0033344cholesterol efflux0.0156759784556345
GO:0008158hedgehog receptor activity0.0156759784556345
GO:0007041lysosomal transport0.0156759784556345
GO:0008206bile acid metabolic process0.0156759784556345
GO:0016236macroautophagy0.0156759784556345
GO:0030301cholesterol transport0.0156759784556345
GO:0015918sterol transport0.0156759784556345
GO:0007034vacuolar transport0.0156759784556345
GO:0042632cholesterol homeostasis0.0156759784556345
GO:0055088lipid homeostasis0.0156759784556345
GO:0055092sterol homeostasis0.0156759784556345
GO:0006914autophagy0.0196872959981344



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
endoderm-derived structure5.46e-16118
endoderm5.46e-16118
presumptive endoderm5.46e-16118
digestive system9.42e-16116
digestive tract9.42e-16116
primitive gut9.42e-16116
subdivision of digestive tract2.76e-15114
endo-epithelium2.68e-0969
gut epithelium2.89e-0955
unilaminar epithelium1.30e-0866
foregut1.48e-0880
organ component layer5.04e-0824
gastrointestinal system2.03e-0747
intestine3.05e-0731
digestive tract diverticulum5.00e-0723
sac5.00e-0723


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.35193
MA0004.11.8803
MA0006.10.60285
MA0007.10.784593
MA0009.11.27673
MA0014.10.416365
MA0017.10.635031
MA0019.11.08369
MA0024.11.23079
MA0025.11.51835
MA0027.12.9431
MA0028.12.53785
MA0029.11.20789
MA0030.11.21482
MA0031.11.17722
MA0038.10.963265
MA0040.11.28983
MA0041.10.714279
MA0042.10.69885
MA0043.11.3775
MA0046.11.31428
MA0048.11.66457
MA0050.10.845669
MA0051.10.973068
MA0052.11.29825
MA0055.10.557057
MA0056.10
MA0057.10.896032
MA0058.12.77886
MA0059.11.68104
MA0060.10.502699
MA0061.10.5406
MA0063.10
MA0066.10.951196
MA0067.11.63197
MA0068.10.343188
MA0069.11.29861
MA0070.11.28847
MA0071.10.844726
MA0072.11.2796
MA0073.10.0430758
MA0074.10.911576
MA0076.12.67392
MA0077.11.2569
MA0078.11.0091
MA0081.10.732313
MA0083.11.37668
MA0084.11.96428
MA0087.11.33189
MA0088.10.766354
MA0089.10
MA0090.10.762482
MA0091.10.816659
MA0092.10.762845
MA0093.12.57012
MA0095.10
MA0098.10
MA0100.10.89873
MA0101.10.71579
MA0103.10.647985
MA0105.12.75918
MA0106.11.01755
MA0107.10.640607
MA0108.21.10817
MA0109.10
MA0111.10.778753
MA0113.10.986839
MA0114.10.537669
MA0115.11.38041
MA0116.11.46662
MA0117.11.34691
MA0119.10.716476
MA0122.11.36752
MA0124.11.57762
MA0125.11.5017
MA0130.10
MA0131.11.07881
MA0132.10
MA0133.10
MA0135.11.4152
MA0136.10.933582
MA0139.10.462282
MA0140.10.898603
MA0141.10.671467
MA0142.11.16183
MA0143.11.00467
MA0144.10.541532
MA0145.11.44606
MA0146.10.900029
MA0147.10.556853
MA0148.10.820161
MA0149.10.722227
MA0062.23.80965
MA0035.20.903829
MA0039.23.91141
MA0138.22.42889
MA0002.20.466067
MA0137.20.668025
MA0104.21.21648
MA0047.20.962424
MA0112.20.29236
MA0065.20.79573
MA0150.10.784464
MA0151.10
MA0152.10.962542
MA0153.11.43238
MA0154.10.35067
MA0155.10.312898
MA0156.10.656895
MA0157.11.12772
MA0158.10
MA0159.10.569393
MA0160.10.823568
MA0161.10
MA0162.11.53682
MA0163.10.477233
MA0164.10.933981
MA0080.20.64167
MA0018.20.944669
MA0099.21.06348
MA0079.21.4764
MA0102.22.01714
MA0258.10.520639
MA0259.10.543506
MA0442.10
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