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MCL coexpression mm9:1569: Difference between revisions

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{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0045084;positive regulation of interleukin-12 biosynthetic process;0.0350425629681184;16362!GO:0042090;interleukin-12 biosynthetic process;0.0350425629681184;16362!GO:0045075;regulation of interleukin-12 biosynthetic process;0.0350425629681184;16362!GO:0015198;oligopeptide transporter activity;0.0350425629681184;21354!GO:0006857;oligopeptide transport;0.0350425629681184;21354!GO:0015197;peptide transporter activity;0.0350425629681184;21354!GO:0032615;interleukin-12 production;0.0450399136048616;16362!
}}

Latest revision as of 17:08, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr11:53583544..53583559,+p1@Irf1
Mm9::chr17:34324776..34324812,+p3@Tap1
Mm9::chr4:147315035..147315040,+p2@2510039O18Rik
Mm9::chr7:134519511..134519534,-p2@Zfp747
Mm9::chr7:134537118..134537177,-p1@E430018J23Rik
p1@LOC100044339


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0045084positive regulation of interleukin-12 biosynthetic process0.0350425629681184
GO:0042090interleukin-12 biosynthetic process0.0350425629681184
GO:0045075regulation of interleukin-12 biosynthetic process0.0350425629681184
GO:0015198oligopeptide transporter activity0.0350425629681184
GO:0006857oligopeptide transport0.0350425629681184
GO:0015197peptide transporter activity0.0350425629681184
GO:0032615interleukin-12 production0.0450399136048616



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
digestive system5.79e-16116
digestive tract5.79e-16116
primitive gut5.79e-16116
endoderm-derived structure1.85e-15118
endoderm1.85e-15118
presumptive endoderm1.85e-15118
subdivision of digestive tract7.01e-15114
intestine8.92e-1331
gastrointestinal system3.94e-1247
mucosa2.49e-1015
hemolymphoid system6.27e-1048
immune system6.27e-1048
organ component layer3.14e-0924
intestinal mucosa4.00e-0913
anatomical wall4.00e-0913
wall of intestine4.00e-0913
gastrointestinal system mucosa4.00e-0913
hematopoietic system1.20e-0845
blood island1.20e-0845
connective tissue1.86e-0846
unilaminar epithelium4.46e-0866
gut epithelium4.14e-0755


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.6678
MA0004.10.603793
MA0006.10.419915
MA0007.10.587678
MA0009.11.06266
MA0014.13.30772
MA0017.10.449113
MA0019.10.874061
MA0024.11.01759
MA0025.11.30092
MA0027.12.72141
MA0028.10.43138
MA0029.10.995171
MA0030.11.00195
MA0031.10.965177
MA0038.10.757669
MA0040.11.07552
MA0041.10.522007
MA0042.10.507715
MA0043.11.1618
MA0046.11.09955
MA0048.10.205696
MA0050.11.55615
MA0051.10.767098
MA0052.11.08379
MA0055.10.0851423
MA0056.10
MA0057.10.192781
MA0058.11.25013
MA0059.10.513699
MA0060.10.881183
MA0061.10.955135
MA0063.10
MA0066.10.746072
MA0067.11.41352
MA0068.10.197245
MA0069.11.08414
MA0070.11.07418
MA0071.10.644448
MA0072.11.06547
MA0073.10.465551
MA0074.10.708108
MA0076.10.470037
MA0077.11.04318
MA0078.10.801834
MA0081.10.53877
MA0083.11.16099
MA0084.11.74401
MA0087.11.11687
MA0088.10.453686
MA0089.10
MA0090.10.566938
MA0091.10.617887
MA0092.10.567278
MA0093.11.12162
MA0095.10
MA0098.10
MA0100.10.695835
MA0101.10.523409
MA0103.10.460936
MA0105.10.693075
MA0106.10.809991
MA0107.11.15122
MA0108.20.897859
MA0109.10
MA0111.10.582193
MA0113.10.780358
MA0114.10.361633
MA0115.11.16466
MA0116.10.419688
MA0117.11.13165
MA0119.10.524046
MA0122.11.15196
MA0124.11.35963
MA0125.11.28445
MA0130.10
MA0131.12.01917
MA0132.10
MA0133.10
MA0135.11.19898
MA0136.10.729175
MA0139.10.295945
MA0140.10.695713
MA0141.10.482463
MA0142.10.950155
MA0143.10.797553
MA0144.10.365053
MA0145.10.927481
MA0146.10.822925
MA0147.10.378658
MA0148.10.621195
MA0149.10.529387
MA0062.20.706751
MA0035.20.700704
MA0039.25.64811
MA0138.20.861035
MA0002.20.299191
MA0137.20.479301
MA0104.20.315156
MA0047.20.75686
MA0112.20.927461
MA0065.20.477991
MA0150.10.587557
MA0151.10
MA0152.10.756973
MA0153.11.21594
MA0154.10.587595
MA0155.10.515751
MA0156.11.18326
MA0157.10.91689
MA0158.10
MA0159.10.389847
MA0160.10.624415
MA0161.10
MA0162.11.35147
MA0163.10.497328
MA0164.10.729558
MA0080.20.455167
MA0018.20.739807
MA0099.20.854449
MA0079.22.32359
MA0102.21.79669
MA0258.10.346619
MA0259.11.71005
MA0442.10
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