MCL coexpression mm9:830: Difference between revisions
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{{MCL_coexpression_mm9 | {{MCL_coexpression_mm9|coexpression_dpi_cluster_scores_mean=-0.127301762698118,0.621083263741989,0.396411718761435,0.667749862268283,0.635311364834895,0.206285732566206,0.331270087461261,0.0784747259819073,0.125426813359816,0.102143732934516,-0.00281213729149027,0.0382154258756091,-0.0382689192316691,-0.0137085870343644,0.775757380411109,0.759662439339367,0.597730950241945,1.38560943076857,1.33040666562529,1.1411904622783,0.460705681570375,0.199167579311176,0.108235454399167,0.802901247381418,0.72317605931613,0.56729018304847,0.506480350607267,0.554631918472757,1.02978361216208,0.967131095384789,0.66709636797509,-0.19196857238014,-0.19196857238014,-0.19196857238014,0.593927269062317,0.633401542050653,0.589282209013931,0.0201051863933104,0.00325849763192234,0.0387555392522096,0.145370454705508,0.101337205917041,0.118511191031061,-0.15541241849242,-0.140157647869352,-0.098415003066743,-0.164079342993792,-0.137425849130149,-0.135888142837094,-0.11802252675687,-0.168726843023151,-0.126604410726871,1.45366920334598,0.275772247672362,0.243987863473531,-0.19196857238014,-0.170107773790698,-0.151834071464463,-0.149351172427683,-0.19196857238014,-0.140566160343011,-0.167000630865583,-0.142654749642202,0.461203885003018,0.503804536641089,0.520740738924459,-0.0691846342982098,-0.0627317462871364,-0.182447026806168,-0.19196857238014,-0.182757240143499,-0.0485722345004029,0.00851517552587095,-0.181394913230375,-0.165629688379342,-0.19196857238014,-0.135805860717683,-0.0385795312496132,-0.13464889542773,-0.151231493662568,-0.14990818462223,-0.171734741507616,0.0256428306353436,0.061924238678857,0.0908790876965337,-0.0519787317633029,-0.0737893814458161,-0.147497658908188,-0.122586253772996,-0.161291519216089,0.047856367701739,0.302400031763536,-0.141901489895922,-0.00951329429325544,0.0136125372703934,0.00955069757252246,0.410433647985906,-0.184374620755798,-0.180824485789752,-0.19196857238014,-0.173634353850289,-0.0907683387206074,-0.130858569624805,-0.19196857238014,-0.174608487933218,-0.172187186210679,-0.172225482214365,0.492809163776326,1.17413858926903,0.572057905315784,0.016065998544531,-0.0251005401096085,-0.035843230695447,-0.0214747703721484,-0.00886669162859225,0.209911218069414,-0.0709318316983032,0.512389317049521,0.520963693500091,0.0191018055238881,0.178752314827925,0.227083689351734,0.486918219235987,-0.0637712434078472,-0.0749935128088021,1.02074984130375,0.160812758285338,0.144615302040394,0.17604936669812,0.0079764822280919,-0.0715538420681713,-0.172318748378341,-0.0127136350484521,-0.106860148380535,-0.0118891930005821,-0.105841070202176,-0.0100813865616967,0.344921092007078,0.368602553136021,0.258013962586605,-0.164124540750755,-0.155458658721906,-0.139614974006638,-0.103265754614164,-0.125032154835577,-0.109061271535971,-0.0957560465570116,0.114059880090194,-0.18254865502796,-0.183610727962036,-0.146963385442935,-0.0848776398100773,-0.070010571316619,-0.0415267888137697,0.00199148117095946,-0.0843612129600509,-0.0280811711222176,0.026353949973744,0.0810095572367571,-0.17524338772683,-0.131311394835632,-0.107804163303615,-0.0622773238371567,-0.00772617997083916,-0.0966186253962183,-0.119121358485238,-0.0642136534798929,-0.00663795685935203,-0.0864120308702798,0.0349675439835474,0.0741353396286198,0.128505697166928,0.23735979257574,0.206619621502979,0.00322495983683129,-0.158698055524467,1.23862463767437,0.340732456411233,-0.150957117171609,-0.155150467695567,-0.0173724290659859,0.0599299879475373,0.126032139488867,0.191917566334547,0.508600206951235,0.179754126909188,0.318595566654522,0.340822174817492,0.380677374383409,0.476932093995852,0.472291017920013,0.449279005348463,-0.0159609074867314,-0.0317374266391522,0.03207685058415,0.0104831352688562,0.0442970610589317,0.0411224518032656,0.114222846787292,0.264713537381574,0.250306586410868,0.277746298775886,0.258689553695706,-0.184522660278125,-0.116949712775627,-0.13603608229427,-0.0440786483984863,0.0197631177335207,0.0569712709077553,0.039484070526923,0.0794621349336813,0.163911796278928,0.267281091779144,0.329861336385936,0.264862457253711,0.211769042311735,0.154533444968808,0.241160189375837,0.849484957327954,-0.129505325323438,-0.121513212000312,-0.0960328447036988,-0.0497776852841576,0.10310299605345,0.0158201364566955,0.125728545200004,0.378701850268205,0.452173109660569,0.493578467414827,0.630393827565887,0.740429699046139,0.736752411904974,0.692335050109112,0.56142782308217,0.534792915083098,0.63850290379927,0.0723408920720363,-0.0657350633011204,-0.19196857238014,0.19247666153647,-0.159828582418043,-0.101924978089879,-0.174680446247336,-0.165885614828078,-0.19196857238014,-0.19196857238014,-0.163347714130988,-0.0940712702204254,-0.117244555612525,0.05940913565725,0.414782375676965,-0.0331582781751237,-0.0168255506063822,0.502878456454301,0.433620586011666,-0.115850473471421,-0.0732489001016619,-0.031145934843528,0.0537624902895662,0.0537102189387262,0.109082369491005,0.0786890496532805,0.0697137413927157,0.278341756477155,0.212398924228738,0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,0,0,0,0,0,0,0,0,0,0,0,0,0,0|gostat_on_MCL_coexpression=GO:0002495;antigen processing and presentation of peptide antigen via MHC class II;2.9402805329924e-08;14961,14960,16149!GO:0019886;antigen processing and presentation of exogenous peptide antigen via MHC class II;2.9402805329924e-08;14961,14960,16149!GO:0002478;antigen processing and presentation of exogenous peptide antigen;2.9402805329924e-08;14961,14960,16149!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;2.9402805329924e-08;14961,14960,16149!GO:0019884;antigen processing and presentation of exogenous antigen;4.29906032935359e-08;14961,14960,16149!GO:0048002;antigen processing and presentation of peptide antigen;1.21050145919687e-07;14961,14960,16149!GO:0019882;antigen processing and presentation;5.07342523339865e-07;14961,14960,16149!GO:0009897;external side of plasma membrane;6.22101460138392e-06;14961,14960,16149!GO:0005771;multivesicular body;8.8585079378312e-06;14961,16149!GO:0042605;peptide antigen binding;1.05010597005964e-05;14961,14960!GO:0042613;MHC class II protein complex;1.05010597005964e-05;14961,14960!GO:0009986;cell surface;1.05010597005964e-05;14961,14960,16149!GO:0045582;positive regulation of T cell differentiation;1.12422584331825e-05;14960,16149!GO:0045621;positive regulation of lymphocyte differentiation;1.66060611691512e-05;14960,16149!GO:0045580;regulation of T cell differentiation;2.00734155611001e-05;14960,16149!GO:0045619;regulation of lymphocyte differentiation;3.50008764403667e-05;14960,16149!GO:0005770;late endosome;4.31568247255248e-05;14961,16149!GO:0042611;MHC protein complex;4.31568247255248e-05;14961,14960!GO:0050870;positive regulation of T cell activation;0.000105122309886019;14960,16149!GO:0006955;immune response;0.000109084407774018;14961,14960,16149!GO:0051251;positive regulation of lymphocyte activation;0.000183866701231306;14960,16149!GO:0030217;T cell differentiation;0.000183866701231306;14960,16149!GO:0050863;regulation of T cell activation;0.000187679693515391;14960,16149!GO:0002376;immune system process;0.000300639969246166;14961,14960,16149!GO:0051249;regulation of lymphocyte activation;0.000300639969246166;14960,16149!GO:0050865;regulation of cell activation;0.000310449579595852;14960,16149!GO:0030098;lymphocyte differentiation;0.000342307974365833;14960,16149!GO:0003823;antigen binding;0.000489796968198964;14961,14960!GO:0042110;T cell activation;0.000525058165040789;14960,16149!GO:0002521;leukocyte differentiation;0.000588094545683921;14960,16149!GO:0042277;peptide binding;0.00059637262044293;14961,14960!GO:0005768;endosome;0.000930175800966296;14961,16149!GO:0005764;lysosome;0.000930175800966296;14960,16149!GO:0000323;lytic vacuole;0.000930175800966296;14960,16149!GO:0046649;lymphocyte activation;0.00106393407006628;14960,16149!GO:0005773;vacuole;0.00106393407006628;14960,16149!GO:0045581;negative regulation of T cell differentiation;0.00106393407006628;16149!GO:0042289;MHC class II protein binding;0.00106393407006628;16149!GO:0045321;leukocyte activation;0.00118324600739464;14960,16149!GO:0030097;hemopoiesis;0.00118324600739464;14960,16149!GO:0001775;cell activation;0.00130294059120673;14960,16149!GO:0048534;hemopoietic or lymphoid organ development;0.00140141979117727;14960,16149!GO:0045620;negative regulation of lymphocyte differentiation;0.00141025393779206;16149!GO:0044459;plasma membrane part;0.00143080160803316;14961,14960,16149!GO:0002520;immune system development;0.00150620481630705;14960,16149!GO:0051239;regulation of multicellular organismal process;0.00183547200533383;14960,16149!GO:0005886;plasma membrane;0.00288702999351992;14961,14960,16149!GO:0045059;positive thymic T cell selection;0.00288702999351992;16149!GO:0043368;positive T cell selection;0.00288702999351992;16149!GO:0043383;negative T cell selection;0.00316989844716695;16149!GO:0045060;negative thymic T cell selection;0.00316989844716695;16149!GO:0042287;MHC protein binding;0.00388574769503132;16149!GO:0051085;chaperone cofactor-dependent protein folding;0.00457441666176633;16149!GO:0045061;thymic T cell selection;0.00505036483165125;16149!GO:0006458;'de novo' protein folding;0.00505036483165125;16149!GO:0051084;'de novo' posttranslational protein folding;0.00505036483165125;16149!GO:0005794;Golgi apparatus;0.00579140002742289;14961,16149!GO:0045058;T cell selection;0.00592014396564938;16149!GO:0050868;negative regulation of T cell activation;0.00616180615516501;16149!GO:0005769;early endosome;0.00774007390611586;14961!GO:0051250;negative regulation of lymphocyte activation;0.00814084023129064;16149!GO:0033077;T cell differentiation in the thymus;0.00814084023129064;16149!GO:0044444;cytoplasmic part;0.00917317022458876;14961,14960,16149!GO:0016064;immunoglobulin mediated immune response;0.0219973520218007;16149!GO:0019724;B cell mediated immunity;0.0219973520218007;16149!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0267246294768124;16149!GO:0002250;adaptive immune response;0.0267246294768124;16149!GO:0048513;organ development;0.0268203057382782;14960,16149!GO:0002449;lymphocyte mediated immunity;0.0268203057382782;16149!GO:0002443;leukocyte mediated immunity;0.0284377538866641;16149!GO:0005515;protein binding;0.0305348782957564;14961,14960,16149!GO:0006461;protein complex assembly;0.0347137540222794;16149!GO:0043234;protein complex;0.0347137540222794;14961,14960!GO:0006457;protein folding;0.0352639211717114;16149!GO:0002252;immune effector process;0.0361220354840267;16149!GO:0048731;system development;0.0365256375817397;14960,16149!GO:0048869;cellular developmental process;0.0374692217593035;14960,16149!GO:0030154;cell differentiation;0.0374692217593035;14960,16149!GO:0005737;cytoplasm;0.0384030814579312;14961,14960,16149!GO:0016021;integral to membrane;0.0454274553912678;14961,14960,16149!GO:0031224;intrinsic to membrane;0.0454274553912678;14961,14960,16149!GO:0048856;anatomical structure development;0.0455408651468514;14960,16149!GO:0032991;macromolecular 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| |||
|coexpression_dpi_cluster_scores_median=0,0.229925105835837,0,0.34436414095139,0.398406570656378,0,0.0911788108631387,0,0,0,0,0,0,0,0.564059533204844,0.4505996990692,0.380052651166226,0.916750210201866,0.917351351299484,0.814052084135445,0.0986886653414259,0.0786677159214676,0,0.465369327652877,0.164001280677683,0,0.155567395918081,0.216538970735966,0.645463687494415,0.631077476625533,0.221464193693345,0,0,0,0.110202921672641,0.124657208673588,0.207501896467584,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.931977150879228,0,0,0,0,0,0,0,0,0,0,0.278730678120876,0,0.233118029693616,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.00940042648008382,0,0,0,0,0,0,0,0,0,0,0,0.152695919012311,0,0,0,0,0,0,0,0,0,0,0.127930999153497,0.711217042666804,0.309437454069622,0,0,0,0,0,0.0514097768499148,0,0.156487991687508,0.275221618407307,0,0.0866592903778752,0,0.456960520238567,0,0,0.403591009053199,0,0.151740698522749,0.0519509775191307,0,0,0,0,0,0,0,0,0.137740408373976,0.177665042710266,0.0829439327499637,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0546921007390138,0,0,0.774975232615945,0.184379402587773,0,0,0,0,0,0.0756292965920817,0.332105766172056,0.0138608044974345,0.0973736644748266,0.0788034163803455,0.142992358284344,0.278483662180697,0.270574546258304,0.0788703512227347,0,0,0,0,0.0246341633625798,0,0,0.0597943799295356,0.0633328814307688,0.0505333231410966,0,0,0,0,0,0,0,0,0,0,0,0,0.117946305307076,0,0,0,0.576490833808021,0,0,0,0,0.0672592169170953,0,0.0774164737207147,0.119015009568782,0.086880916817156,0.169781468279214,0.393534813310472,0.511201955076368,0.437082551865967,0.399312438845857,0.501828902533295,0.29743845502323,0.376519241602283,0,0,0,0.0977676536600382,0,0,0,0,0,0,0,0,0,0,0.108524491213051,0,0,0.174615154231399,0.314527736846385,0,0,0,0,0,0,0,0,0.119268019631849,0,0,0,0,0,0,0,0,0,0,0.0915514965999916,0,0.0865478886078475,0.123777349320174,0,0.0494606362651129,0.132937195692582,0.0660055475634404,0.199470399831828,0,0.50803406451455,0,0.0737896374598673,0.430609707592871,0.421658330797668,0.668427924849271,0.0681778550615498,0.107177024667156,0.0562185712770556,0.291073584836546,0,0,0,0,0,0,0.034489466458534,0,0.100105043383282,0.209873913294111,0,0,0,0,0,0,0,0,0,0,0,0.411629065605499,0.303978826688782,0.454661538226934,0.280907326443055,0.31684229110821,0.378537703726113,0.292602393023045,0.338758445881025,0.205691101905468,0.299003304641995,0.324094708222397,0.424356242655487,0.313515058346122,0.312154523555165,0.162403313502186,0,0,0,0.0767094571656325,0.0747003483965965,0.135547100918658,0.0843504501108034,0.176546191435317,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0 | |||
|gostat_on_MCL_coexpression=GO:0002495;antigen processing and presentation of peptide antigen via MHC class II;2.9402805329924e-08;14961,14960,16149!GO:0019886;antigen processing and presentation of exogenous peptide antigen via MHC class II;2.9402805329924e-08;14961,14960,16149!GO:0002478;antigen processing and presentation of exogenous peptide antigen;2.9402805329924e-08;14961,14960,16149!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;2.9402805329924e-08;14961,14960,16149!GO:0019884;antigen processing and presentation of exogenous antigen;4.29906032935359e-08;14961,14960,16149!GO:0048002;antigen processing and presentation of peptide antigen;1.21050145919687e-07;14961,14960,16149!GO:0019882;antigen processing and presentation;5.07342523339865e-07;14961,14960,16149!GO:0009897;external side of plasma membrane;6.22101460138392e-06;14961,14960,16149!GO:0005771;multivesicular body;8.8585079378312e-06;14961,16149!GO:0042605;peptide antigen binding;1.05010597005964e-05;14961,14960!GO:0042613;MHC class II protein complex;1.05010597005964e-05;14961,14960!GO:0009986;cell surface;1.05010597005964e-05;14961,14960,16149!GO:0045582;positive regulation of T cell differentiation;1.12422584331825e-05;14960,16149!GO:0045621;positive regulation of lymphocyte differentiation;1.66060611691512e-05;14960,16149!GO:0045580;regulation of T cell differentiation;2.00734155611001e-05;14960,16149!GO:0045619;regulation of lymphocyte differentiation;3.50008764403667e-05;14960,16149!GO:0005770;late endosome;4.31568247255248e-05;14961,16149!GO:0042611;MHC protein complex;4.31568247255248e-05;14961,14960!GO:0050870;positive regulation of T cell activation;0.000105122309886019;14960,16149!GO:0006955;immune response;0.000109084407774018;14961,14960,16149!GO:0051251;positive regulation of lymphocyte activation;0.000183866701231306;14960,16149!GO:0030217;T cell differentiation;0.000183866701231306;14960,16149!GO:0050863;regulation of T cell activation;0.000187679693515391;14960,16149!GO:0002376;immune system process;0.000300639969246166;14961,14960,16149!GO:0051249;regulation of lymphocyte activation;0.000300639969246166;14960,16149!GO:0050865;regulation of cell activation;0.000310449579595852;14960,16149!GO:0030098;lymphocyte differentiation;0.000342307974365833;14960,16149!GO:0003823;antigen binding;0.000489796968198964;14961,14960!GO:0042110;T cell activation;0.000525058165040789;14960,16149!GO:0002521;leukocyte differentiation;0.000588094545683921;14960,16149!GO:0042277;peptide binding;0.00059637262044293;14961,14960!GO:0005768;endosome;0.000930175800966296;14961,16149!GO:0005764;lysosome;0.000930175800966296;14960,16149!GO:0000323;lytic vacuole;0.000930175800966296;14960,16149!GO:0046649;lymphocyte activation;0.00106393407006628;14960,16149!GO:0005773;vacuole;0.00106393407006628;14960,16149!GO:0045581;negative regulation of T cell differentiation;0.00106393407006628;16149!GO:0042289;MHC class II protein binding;0.00106393407006628;16149!GO:0045321;leukocyte activation;0.00118324600739464;14960,16149!GO:0030097;hemopoiesis;0.00118324600739464;14960,16149!GO:0001775;cell activation;0.00130294059120673;14960,16149!GO:0048534;hemopoietic or lymphoid organ development;0.00140141979117727;14960,16149!GO:0045620;negative regulation of lymphocyte differentiation;0.00141025393779206;16149!GO:0044459;plasma membrane part;0.00143080160803316;14961,14960,16149!GO:0002520;immune system development;0.00150620481630705;14960,16149!GO:0051239;regulation of multicellular organismal process;0.00183547200533383;14960,16149!GO:0005886;plasma membrane;0.00288702999351992;14961,14960,16149!GO:0045059;positive thymic T cell selection;0.00288702999351992;16149!GO:0043368;positive T cell selection;0.00288702999351992;16149!GO:0043383;negative T cell selection;0.00316989844716695;16149!GO:0045060;negative thymic T cell selection;0.00316989844716695;16149!GO:0042287;MHC protein binding;0.00388574769503132;16149!GO:0051085;chaperone cofactor-dependent protein folding;0.00457441666176633;16149!GO:0045061;thymic T cell selection;0.00505036483165125;16149!GO:0006458;'de novo' protein folding;0.00505036483165125;16149!GO:0051084;'de novo' posttranslational protein folding;0.00505036483165125;16149!GO:0005794;Golgi apparatus;0.00579140002742289;14961,16149!GO:0045058;T cell selection;0.00592014396564938;16149!GO:0050868;negative regulation of T cell activation;0.00616180615516501;16149!GO:0005769;early endosome;0.00774007390611586;14961!GO:0051250;negative regulation of lymphocyte activation;0.00814084023129064;16149!GO:0033077;T cell differentiation in the thymus;0.00814084023129064;16149!GO:0044444;cytoplasmic part;0.00917317022458876;14961,14960,16149!GO:0016064;immunoglobulin mediated immune response;0.0219973520218007;16149!GO:0019724;B cell mediated immunity;0.0219973520218007;16149!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0267246294768124;16149!GO:0002250;adaptive immune response;0.0267246294768124;16149!GO:0048513;organ development;0.0268203057382782;14960,16149!GO:0002449;lymphocyte mediated immunity;0.0268203057382782;16149!GO:0002443;leukocyte mediated immunity;0.0284377538866641;16149!GO:0005515;protein binding;0.0305348782957564;14961,14960,16149!GO:0006461;protein complex assembly;0.0347137540222794;16149!GO:0043234;protein complex;0.0347137540222794;14961,14960!GO:0006457;protein folding;0.0352639211717114;16149!GO:0002252;immune effector process;0.0361220354840267;16149!GO:0048731;system development;0.0365256375817397;14960,16149!GO:0048869;cellular developmental process;0.0374692217593035;14960,16149!GO:0030154;cell differentiation;0.0374692217593035;14960,16149!GO:0005737;cytoplasm;0.0384030814579312;14961,14960,16149!GO:0016021;integral to membrane;0.0454274553912678;14961,14960,16149!GO:0031224;intrinsic to membrane;0.0454274553912678;14961,14960,16149!GO:0048856;anatomical structure development;0.0455408651468514;14960,16149!GO:0032991;macromolecular complex;0.0477137550182854;14961,14960! | |||
|ontology_enrichment_celltype=CL:0000553!2.77e-07!6;CL:0000556!2.77e-07!6 | |||
|ontology_enrichment_disease= | |||
|ontology_enrichment_uberon=UBERON:0002193!4.73e-14!48;UBERON:0002405!4.73e-14!48;UBERON:0004119!1.04e-13!118;UBERON:0000925!1.04e-13!118;UBERON:0006595!1.04e-13!118;UBERON:0001007!1.27e-13!116;UBERON:0001555!1.27e-13!116;UBERON:0007026!1.27e-13!116;UBERON:0004921!1.58e-12!114;UBERON:0002390!5.88e-12!45;UBERON:0003061!5.88e-12!45;UBERON:0007023!2.50e-11!51;UBERON:0005409!1.66e-10!47;UBERON:0000160!4.77e-10!31;UBERON:0004923!6.24e-10!24;UBERON:0000077!2.87e-08!35;UBERON:0000344!3.08e-08!15;UBERON:0004177!6.78e-08!29;UBERON:0005057!6.78e-08!29;UBERON:0001004!2.39e-07!42;UBERON:0000065!6.75e-07!41;UBERON:0001242!6.85e-07!13;UBERON:0000060!6.85e-07!13;UBERON:0001262!6.85e-07!13;UBERON:0004786!6.85e-07!13 | |||
}} |
Latest revision as of 15:57, 17 September 2013
Phase1 CAGE Peaks
Short description | |
---|---|
Mm9::chr16:10526522..10526533,+ | p@chr16:10526522..10526533 + |
Mm9::chr17:34400169..34400201,+ | p1@H2-Ab1 |
Mm9::chr17:34401792..34401805,+ | p@chr17:34401792..34401805 + |
Mm9::chr17:34404310..34404328,+ | p4@H2-Ab1 |
Mm9::chr17:34406063..34406072,+ | p@chr17:34406063..34406072 + |
Mm9::chr17:34424715..34424775,- | p1@H2-Aa |
Mm9::chr18:60963511..60963522,+ | p2@Cd74 |
Mm9::chr18:60967650..60967694,+ | p@chr18:60967650..60967694 + |
Mm9::chr18:60971536..60971571,- | p@chr18:60971536..60971571 - |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II | 2.9402805329924e-08 |
GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II | 2.9402805329924e-08 |
GO:0002478 | antigen processing and presentation of exogenous peptide antigen | 2.9402805329924e-08 |
GO:0002504 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | 2.9402805329924e-08 |
GO:0019884 | antigen processing and presentation of exogenous antigen | 4.29906032935359e-08 |
GO:0048002 | antigen processing and presentation of peptide antigen | 1.21050145919687e-07 |
GO:0019882 | antigen processing and presentation | 5.07342523339865e-07 |
GO:0009897 | external side of plasma membrane | 6.22101460138392e-06 |
GO:0005771 | multivesicular body | 8.8585079378312e-06 |
GO:0042605 | peptide antigen binding | 1.05010597005964e-05 |
GO:0042613 | MHC class II protein complex | 1.05010597005964e-05 |
GO:0009986 | cell surface | 1.05010597005964e-05 |
GO:0045582 | positive regulation of T cell differentiation | 1.12422584331825e-05 |
GO:0045621 | positive regulation of lymphocyte differentiation | 1.66060611691512e-05 |
GO:0045580 | regulation of T cell differentiation | 2.00734155611001e-05 |
GO:0045619 | regulation of lymphocyte differentiation | 3.50008764403667e-05 |
GO:0005770 | late endosome | 4.31568247255248e-05 |
GO:0042611 | MHC protein complex | 4.31568247255248e-05 |
GO:0050870 | positive regulation of T cell activation | 0.000105122309886019 |
GO:0006955 | immune response | 0.000109084407774018 |
GO:0051251 | positive regulation of lymphocyte activation | 0.000183866701231306 |
GO:0030217 | T cell differentiation | 0.000183866701231306 |
GO:0050863 | regulation of T cell activation | 0.000187679693515391 |
GO:0002376 | immune system process | 0.000300639969246166 |
GO:0051249 | regulation of lymphocyte activation | 0.000300639969246166 |
GO:0050865 | regulation of cell activation | 0.000310449579595852 |
GO:0030098 | lymphocyte differentiation | 0.000342307974365833 |
GO:0003823 | antigen binding | 0.000489796968198964 |
GO:0042110 | T cell activation | 0.000525058165040789 |
GO:0002521 | leukocyte differentiation | 0.000588094545683921 |
GO:0042277 | peptide binding | 0.00059637262044293 |
GO:0005768 | endosome | 0.000930175800966296 |
GO:0005764 | lysosome | 0.000930175800966296 |
GO:0000323 | lytic vacuole | 0.000930175800966296 |
GO:0046649 | lymphocyte activation | 0.00106393407006628 |
GO:0005773 | vacuole | 0.00106393407006628 |
GO:0045581 | negative regulation of T cell differentiation | 0.00106393407006628 |
GO:0042289 | MHC class II protein binding | 0.00106393407006628 |
GO:0045321 | leukocyte activation | 0.00118324600739464 |
GO:0030097 | hemopoiesis | 0.00118324600739464 |
GO:0001775 | cell activation | 0.00130294059120673 |
GO:0048534 | hemopoietic or lymphoid organ development | 0.00140141979117727 |
GO:0045620 | negative regulation of lymphocyte differentiation | 0.00141025393779206 |
GO:0044459 | plasma membrane part | 0.00143080160803316 |
GO:0002520 | immune system development | 0.00150620481630705 |
GO:0051239 | regulation of multicellular organismal process | 0.00183547200533383 |
GO:0005886 | plasma membrane | 0.00288702999351992 |
GO:0045059 | positive thymic T cell selection | 0.00288702999351992 |
GO:0043368 | positive T cell selection | 0.00288702999351992 |
GO:0043383 | negative T cell selection | 0.00316989844716695 |
GO:0045060 | negative thymic T cell selection | 0.00316989844716695 |
GO:0042287 | MHC protein binding | 0.00388574769503132 |
GO:0051085 | chaperone cofactor-dependent protein folding | 0.00457441666176633 |
GO:0045061 | thymic T cell selection | 0.00505036483165125 |
GO:0006458 | 'de novo' protein folding | 0.00505036483165125 |
GO:0051084 | 'de novo' posttranslational protein folding | 0.00505036483165125 |
GO:0005794 | Golgi apparatus | 0.00579140002742289 |
GO:0045058 | T cell selection | 0.00592014396564938 |
GO:0050868 | negative regulation of T cell activation | 0.00616180615516501 |
GO:0005769 | early endosome | 0.00774007390611586 |
GO:0051250 | negative regulation of lymphocyte activation | 0.00814084023129064 |
GO:0033077 | T cell differentiation in the thymus | 0.00814084023129064 |
GO:0044444 | cytoplasmic part | 0.00917317022458876 |
GO:0016064 | immunoglobulin mediated immune response | 0.0219973520218007 |
GO:0019724 | B cell mediated immunity | 0.0219973520218007 |
GO:0002460 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 0.0267246294768124 |
GO:0002250 | adaptive immune response | 0.0267246294768124 |
GO:0048513 | organ development | 0.0268203057382782 |
GO:0002449 | lymphocyte mediated immunity | 0.0268203057382782 |
GO:0002443 | leukocyte mediated immunity | 0.0284377538866641 |
GO:0005515 | protein binding | 0.0305348782957564 |
GO:0006461 | protein complex assembly | 0.0347137540222794 |
GO:0043234 | protein complex | 0.0347137540222794 |
GO:0006457 | protein folding | 0.0352639211717114 |
GO:0002252 | immune effector process | 0.0361220354840267 |
GO:0048731 | system development | 0.0365256375817397 |
GO:0048869 | cellular developmental process | 0.0374692217593035 |
GO:0030154 | cell differentiation | 0.0374692217593035 |
GO:0005737 | cytoplasm | 0.0384030814579312 |
GO:0016021 | integral to membrane | 0.0454274553912678 |
GO:0031224 | intrinsic to membrane | 0.0454274553912678 |
GO:0048856 | anatomical structure development | 0.0455408651468514 |
GO:0032991 | macromolecular complex | 0.0477137550182854 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
megakaryocyte progenitor cell | 2.77e-07 | 6 |
megakaryocyte | 2.77e-07 | 6 |
Ontology term | p-value | n |
---|---|---|
hemolymphoid system | 4.73e-14 | 48 |
immune system | 4.73e-14 | 48 |
endoderm-derived structure | 1.04e-13 | 118 |
endoderm | 1.04e-13 | 118 |
presumptive endoderm | 1.04e-13 | 118 |
digestive system | 1.27e-13 | 116 |
digestive tract | 1.27e-13 | 116 |
primitive gut | 1.27e-13 | 116 |
subdivision of digestive tract | 1.58e-12 | 114 |
hematopoietic system | 5.88e-12 | 45 |
blood island | 5.88e-12 | 45 |
adult organism | 2.50e-11 | 51 |
gastrointestinal system | 1.66e-10 | 47 |
intestine | 4.77e-10 | 31 |
organ component layer | 6.24e-10 | 24 |
mixed endoderm/mesoderm-derived structure | 2.87e-08 | 35 |
mucosa | 3.08e-08 | 15 |
hemopoietic organ | 6.78e-08 | 29 |
immune organ | 6.78e-08 | 29 |
respiratory system | 2.39e-07 | 42 |
respiratory tract | 6.75e-07 | 41 |
intestinal mucosa | 6.85e-07 | 13 |
anatomical wall | 6.85e-07 | 13 |
wall of intestine | 6.85e-07 | 13 |
gastrointestinal system mucosa | 6.85e-07 | 13 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.170768 |
MA0004.1 | 0.394951 |
MA0006.1 | 0.670874 |
MA0007.1 | 0.991467 |
MA0009.1 | 1.92363 |
MA0014.1 | 0.00813637 |
MA0017.1 | 0.726051 |
MA0019.1 | 0.642876 |
MA0024.1 | 0.779446 |
MA0025.1 | 1.05446 |
MA0027.1 | 2.46647 |
MA0028.1 | 0.24786 |
MA0029.1 | 0.757957 |
MA0030.1 | 0.764448 |
MA0031.1 | 0.729293 |
MA0038.1 | 0.534262 |
MA0040.1 | 0.835181 |
MA0041.1 | 0.323687 |
MA0042.1 | 0.311486 |
MA0043.1 | 0.918718 |
MA0046.1 | 0.858391 |
MA0048.1 | 0.281053 |
MA0050.1 | 1.10321 |
MA0051.1 | 0.542972 |
MA0052.1 | 0.84317 |
MA0055.1 | 7.45031 |
MA0056.1 | 0 |
MA0057.1 | 0.0745664 |
MA0058.1 | 0.305206 |
MA0059.1 | 0.316585 |
MA0060.1 | 0.9744 |
MA0061.1 | 2.40227 |
MA0063.1 | 0 |
MA0066.1 | 0.523573 |
MA0067.1 | 1.16502 |
MA0068.1 | 0.077274 |
MA0069.1 | 0.843506 |
MA0070.1 | 0.833895 |
MA0071.1 | 0.431174 |
MA0072.1 | 1.92922 |
MA0073.1 | 0.00959692 |
MA0074.1 | 0.488775 |
MA0076.1 | 0.279739 |
MA0077.1 | 0.804033 |
MA0078.1 | 0.575205 |
MA0081.1 | 0.338098 |
MA0083.1 | 0.917931 |
MA0084.1 | 1.49188 |
MA0087.1 | 0.87515 |
MA0088.1 | 0.18495 |
MA0089.1 | 0 |
MA0090.1 | 0.362551 |
MA0091.1 | 1.04993 |
MA0092.1 | 0.362847 |
MA0093.1 | 0.2553 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.477594 |
MA0101.1 | 0.867731 |
MA0103.1 | 0.748482 |
MA0105.1 | 2.3545 |
MA0106.1 | 0.582805 |
MA0107.1 | 2.89998 |
MA0108.2 | 0.665343 |
MA0109.1 | 0 |
MA0111.1 | 0.375908 |
MA0113.1 | 0.555251 |
MA0114.1 | 0.19245 |
MA0115.1 | 0.921497 |
MA0116.1 | 0.238371 |
MA0117.1 | 0.88947 |
MA0119.1 | 0.325434 |
MA0122.1 | 0.909168 |
MA0124.1 | 1.11203 |
MA0125.1 | 1.03833 |
MA0130.1 | 0 |
MA0131.1 | 0.638414 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.954884 |
MA0136.1 | 0.508047 |
MA0139.1 | 1.39725 |
MA0140.1 | 0.477483 |
MA0141.1 | 0.29014 |
MA0142.1 | 0.714976 |
MA0143.1 | 0.571221 |
MA0144.1 | 0.195095 |
MA0145.1 | 0.77191 |
MA0146.1 | 0.30073 |
MA0147.1 | 0.593505 |
MA0148.1 | 0.410398 |
MA0149.1 | 0.330018 |
MA0062.2 | 0.113962 |
MA0035.2 | 0.482026 |
MA0039.2 | 0.043355 |
MA0138.2 | 0.630612 |
MA0002.2 | 0.447007 |
MA0137.2 | 0.287486 |
MA0104.2 | 0.476119 |
MA0047.2 | 0.533516 |
MA0112.2 | 0.442124 |
MA0065.2 | 0.200864 |
MA0150.1 | 0.380623 |
MA0151.1 | 0 |
MA0152.1 | 0.53362 |
MA0153.1 | 0.971406 |
MA0154.1 | 0.581988 |
MA0155.1 | 0.226288 |
MA0156.1 | 0.278949 |
MA0157.1 | 0.683365 |
MA0158.1 | 0 |
MA0159.1 | 0.614411 |
MA0160.1 | 0.413266 |
MA0161.1 | 0 |
MA0162.1 | 0.176565 |
MA0163.1 | 0.321031 |
MA0164.1 | 0.508398 |
MA0080.2 | 0.267388 |
MA0018.2 | 0.51781 |
MA0099.2 | 0.624421 |
MA0079.2 | 0.000240419 |
MA0102.2 | 1.5442 |
MA0258.1 | 1.61881 |
MA0259.1 | 0.571417 |
MA0442.1 | 0 |