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MCL coexpression mm9:1221: Difference between revisions

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{{MCL_coexpression_mm9
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|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0005409!5.58e-25!47;UBERON:0000160!4.51e-23!31;UBERON:0001007!1.58e-13!116;UBERON:0001555!1.58e-13!116;UBERON:0007026!1.58e-13!116;UBERON:0004119!5.09e-13!118;UBERON:0000925!5.09e-13!118;UBERON:0006595!5.09e-13!118;UBERON:0004921!3.08e-12!114;UBERON:0000344!2.01e-11!15;UBERON:0001242!1.43e-09!13;UBERON:0000060!1.43e-09!13;UBERON:0001262!1.43e-09!13;UBERON:0004786!1.43e-09!13;UBERON:0000485!2.77e-07!11
|tfbs_overrepresentation_for_novel_motifs=0.491922,0.217198,0.464605,0.535892,0.916672,0.550971,0.645383,0.247459,0.257202,0.283981,0.599767,0.632897,0.247704,0.6581,0.364314,0,0.856992,0.338549,0.656199,0.143775,0.426133,0.713088,0.657163,3.40146,0.472505,0.686615,0.63639,0.572827,0.394364,0.181062,1.37295,0.960397,0.336199,0.589948,2.56614,0.607065,0.326478,0.629145,0.303703,0.27383,0.342638,0.56353,0.327433,0.366415,0.161543,0.524258,0.77511,1.43855,0.284064,0.397446,0.839084,0.714419,0.174327,1.10437,1.12205,0.66551,0.406788,0.619643,0.21472,0.663395,0.939962,0.724164,0.269393,1.93338,0.677043,0.869046,1.2599,1.61148,0.935192,1.46355,0.444872,0.253541,0.11437,1.156,0.208101,0.19692,0.589776,0.763395,0.922432,0.430551,0.254777,0.874787,0.722675,0.240896,1.03903,0.0539203,0.0610418,1.02367,0.780154,1.77427,1.33021,1.04409,0.973447,0.35304,0.2995,0.281222,0.244935,0.976308,0.775372,2.14669,1.56871,0.960112,1.08669,0.839694,0.838613,0.563071,0.8998,0.585058,0.435642,0.428007,1.21641,1.0885,1.10269,0.605144,1.33732,0.340765,0.247162,0.53982,0.858327,0.322606,1.16147,0.805995,0.688501,0.762461,1.39185,0.926209,0.65384,0.966541,1.25836,2.52463,1.06946,0.52828,1.2285,0.679647,1.35909,0.106956,0.500709,0.564999,1.30952,2.14327,1.74232,1.26465,0.700956,2.22711,0.831964,0.564002,0.778321,2.10357,0.503174,0.348692,0.183562,0.0987301,1.10596,0.287383,0.678689,1.18867,0.71546,0.376898,0.48935,1.25034,1.31911,1.03816,0.926663,0.482185,0.82857,0.671017,0.325308,0.63125,0.30995
}}

Latest revision as of 16:35, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr10:12268528..12268573,-p@chr10:12268528..12268573
-
Mm9::chr18:62483479..62483498,+p2@Htr4
Mm9::chr2:24950600..24950612,-p3@Noxa1
Mm9::chr2:24950615..24950630,-p4@Noxa1
Mm9::chr2:24950645..24950658,-p2@Noxa1
Mm9::chr2:24950672..24950689,-p1@Noxa1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0016176superoxide-generating NADPH oxidase activator activity0.00569753744574322
GO:0004993serotonin receptor activity0.00712133649185093
GO:0004935adrenoceptor activity0.0104429099297523
GO:0006801superoxide metabolic process0.0106790781611359
GO:0006800oxygen and reactive oxygen species metabolic process0.0165106372086046
GO:0008227amine receptor activity0.0203932444933924



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
gastrointestinal system5.58e-2547
intestine4.51e-2331
digestive system1.58e-13116
digestive tract1.58e-13116
primitive gut1.58e-13116
endoderm-derived structure5.09e-13118
endoderm5.09e-13118
presumptive endoderm5.09e-13118
subdivision of digestive tract3.08e-12114
mucosa2.01e-1115
intestinal mucosa1.43e-0913
anatomical wall1.43e-0913
wall of intestine1.43e-0913
gastrointestinal system mucosa1.43e-0913
simple columnar epithelium2.77e-0711


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.276983
MA0004.10.536396
MA0006.10.359699
MA0007.10.52077
MA0009.10.987341
MA0014.10.0315641
MA0017.10.387481
MA0019.10.800946
MA0024.10.942716
MA0025.11.22395
MA0027.12.64231
MA0028.10.370592
MA0029.10.920529
MA0030.10.927235
MA0031.10.890871
MA0038.10.686534
MA0040.11.00009
MA0041.10.457338
MA0042.10.443591
MA0043.11.08567
MA0046.11.02391
MA0048.10.943003
MA0050.10.57678
MA0051.10.695779
MA0052.11.00829
MA0055.13.51526
MA0056.10
MA0057.10.149949
MA0058.10.436487
MA0059.10.449345
MA0060.10.275911
MA0061.10.307097
MA0063.10
MA0066.12.72895
MA0067.11.33603
MA0068.10.153907
MA0069.11.00864
MA0070.10.998765
MA0071.10.575909
MA0072.10.990133
MA0073.10.0198269
MA0074.10.638014
MA0076.10.407465
MA0077.10.968053
MA0078.10.729877
MA0081.10.473489
MA0083.11.08487
MA0084.11.66561
MA0087.11.04109
MA0088.10.111145
MA0089.10
MA0090.10.500693
MA0091.13.41531
MA0092.10.501022
MA0093.10.379257
MA0095.10
MA0098.10
MA0100.10.626021
MA0101.11.16089
MA0103.11.03097
MA0105.10.57901
MA0106.10.737893
MA0107.11.0169
MA0108.20.824407
MA0109.10
MA0111.10.515457
MA0113.10.708789
MA0114.10.304661
MA0115.11.08851
MA0116.10.359483
MA0117.11.05576
MA0119.11.16221
MA0122.11.07591
MA0124.11.28237
MA0125.11.20757
MA0130.10
MA0131.10.796279
MA0132.10
MA0133.10
MA0135.11.1226
MA0136.10.658622
MA0139.10.243463
MA0140.12.57126
MA0141.11.07584
MA0142.10.876028
MA0143.10.725672
MA0144.14.12203
MA0145.10.761789
MA0146.10.990842
MA0147.10.320675
MA0148.10.553294
MA0149.10.464445
MA0062.20.591842
MA0035.22.58693
MA0039.21.05907
MA0138.21.85228
MA0002.20.246463
MA0137.21.88035
MA0104.20.261255
MA0047.20.685741
MA0112.21.81396
MA0065.20.763394
MA0150.10.520653
MA0151.10
MA0152.10.685852
MA0153.11.13945
MA0154.10.480757
MA0155.10.132921
MA0156.10.406559
MA0157.10.843181
MA0158.10
MA0159.10.331229
MA0160.10.556423
MA0161.10
MA0162.10.0465447
MA0163.10.372305
MA0164.10.658997
MA0080.21.01893
MA0018.20.669032
MA0099.20.781628
MA0079.20.00464563
MA0102.21.7182
MA0258.10.790457
MA0259.10.833237
MA0442.10
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