Novel motif:84

name:	motif84_GGKTTYT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0050794	regulation of cellular process	4.727066e-25
GO:0050789	regulation of biological process	1.964096e-21
GO:0050896	response to stimulus	3.716816e-19
GO:0051716	cellular response to stimulus	4.133071e-18
GO:0065007	biological regulation	8.552233e-17
GO:0048583	regulation of response to stimulus	1.224485e-16
GO:0002376	immune system process	7.592532e-16
GO:0044260	cellular macromolecule metabolic process	5.419725e-15
GO:0043170	macromolecule metabolic process	2.163799e-14
GO:0048518	positive regulation of biological process	3.014595e-14
GO:0006955	immune response	8.480524e-14
GO:0006950	response to stress	9.204713e-13
GO:0048523	negative regulation of cellular process	1.628784e-12
GO:0048519	negative regulation of biological process	2.906022e-12
GO:0007165	signal transduction	6.429435e-12
GO:0048522	positive regulation of cellular process	7.948844e-12
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	8.852716e-11
GO:0016576	histone dephosphorylation	1.357253e-10
GO:0010035	response to inorganic substance	1.833500e-10
GO:0033157	regulation of intracellular protein transport	2.138698e-10
GO:0010038	response to metal ion	3.193753e-10
GO:0048584	positive regulation of response to stimulus	4.367097e-10
GO:0001775	cell activation	5.112689e-10
GO:0032386	regulation of intracellular transport	5.168451e-10
GO:0045165	cell fate commitment	7.732788e-10
GO:0042127	regulation of cell proliferation	8.621747e-10
GO:0044238	primary metabolic process	1.653819e-9
GO:0006935	chemotaxis	2.393689e-9
GO:0009966	regulation of signal transduction	5.016908e-9
GO:0006552	leucine catabolic process	6.263779e-9
GO:0048002	antigen processing and presentation of peptide antigen	6.964137e-9
GO:0006139	nucleobase-containing compound metabolic process	7.283625e-9
GO:0007154	cell communication	1.118570e-8
GO:0051223	regulation of protein transport	1.701607e-8
GO:0023052	signaling	1.846989e-8
GO:0032880	regulation of protein localization	2.362768e-8
GO:0085020	protein K6-linked ubiquitination	2.695793e-8
GO:0022403	cell cycle phase	2.945257e-8
GO:0009611	response to wounding	3.871823e-8
GO:0006323	DNA packaging	4.164220e-8
GO:0009059	macromolecule biosynthetic process	4.797200e-8
GO:0042060	wound healing	5.156224e-8
GO:0016310	phosphorylation	5.229104e-8
GO:0009888	tissue development	5.835267e-8
GO:0007596	blood coagulation	6.428027e-8
GO:0045666	positive regulation of neuron differentiation	6.569340e-8
GO:0002682	regulation of immune system process	6.859014e-8
GO:0090230	regulation of centromere complex assembly	7.345780e-8
GO:0051329	interphase of mitotic cell cycle	9.779032e-8
GO:0007599	hemostasis	1.066251e-7
GO:0006468	protein phosphorylation	1.094406e-7
GO:0090304	nucleic acid metabolic process	1.135153e-7
GO:0010558	negative regulation of macromolecule biosynthetic process	1.240133e-7
GO:0030241	skeletal muscle myosin thick filament assembly	1.261445e-7
GO:0000278	mitotic cell cycle	1.355956e-7
GO:0010810	regulation of cell-substrate adhesion	1.377906e-7
GO:0048468	cell development	1.510890e-7
GO:0030261	chromosome condensation	1.660223e-7
GO:0010605	negative regulation of macromolecule metabolic process	1.783513e-7
GO:0000082	G1/S transition of mitotic cell cycle	1.843454e-7
GO:0006952	defense response	2.062553e-7
GO:0002253	activation of immune response	2.077740e-7
GO:0048869	cellular developmental process	2.339936e-7
GO:0030154	cell differentiation	2.514830e-7
GO:0051641	cellular localization	2.515397e-7
GO:0034645	cellular macromolecule biosynthetic process	2.673825e-7
GO:0022402	cell cycle process	2.723802e-7
GO:0009892	negative regulation of metabolic process	2.837038e-7
GO:0042221	response to chemical stimulus	2.844252e-7
GO:0090316	positive regulation of intracellular protein transport	3.339556e-7
GO:0070201	regulation of establishment of protein localization	3.412232e-7
GO:0009653	anatomical structure morphogenesis	3.532766e-7
GO:0010646	regulation of cell communication	3.590589e-7
GO:0060284	regulation of cell development	3.680114e-7
GO:0032388	positive regulation of intracellular transport	3.747213e-7
GO:0050688	regulation of defense response to virus	3.814010e-7
GO:0031327	negative regulation of cellular biosynthetic process	4.211991e-7
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	4.214140e-7
GO:0051094	positive regulation of developmental process	4.287238e-7
GO:0046822	regulation of nucleocytoplasmic transport	4.747194e-7
GO:0045597	positive regulation of cell differentiation	4.777283e-7
GO:0002689	negative regulation of leukocyte chemotaxis	4.890047e-7
GO:0006386	termination of RNA polymerase III transcription	5.319978e-7
GO:0006385	transcription elongation from RNA polymerase III promoter	5.319978e-7
GO:0042306	regulation of protein import into nucleus	5.495529e-7
GO:0031324	negative regulation of cellular metabolic process	5.503918e-7
GO:0051325	interphase	5.556235e-7
GO:0007166	cell surface receptor linked signaling pathway	5.589159e-7
GO:0048729	tissue morphogenesis	6.226163e-7
GO:0030168	platelet activation	6.398850e-7
GO:0050710	negative regulation of cytokine secretion	6.450520e-7
GO:0006928	cellular component movement	6.750672e-7
GO:0046631	alpha-beta T cell activation	6.850220e-7
GO:0031347	regulation of defense response	7.080869e-7
GO:0008284	positive regulation of cell proliferation	7.521092e-7
GO:0051915	induction of synaptic plasticity by chemical substance	8.635124e-7
GO:0043134	regulation of hindgut contraction	8.755123e-7
GO:0022612	gland morphogenesis	9.628808e-7
GO:0006464	protein modification process	9.867160e-7
GO:0034063	stress granule assembly	1.001808e-6
GO:0051224	negative regulation of protein transport	1.094662e-6
GO:0048015	phosphatidylinositol-mediated signaling	1.112695e-6
GO:0034504	protein localization to nucleus	1.142604e-6
GO:0080134	regulation of response to stress	1.189977e-6
GO:0010888	negative regulation of lipid storage	1.217780e-6
GO:0048385	regulation of retinoic acid receptor signaling pathway	1.230152e-6
GO:0016070	RNA metabolic process	1.327309e-6
GO:0032879	regulation of localization	1.341687e-6
GO:0012501	programmed cell death	1.489067e-6
GO:0048513	organ development	1.537150e-6
GO:0032989	cellular component morphogenesis	1.538627e-6
GO:0007343	egg activation	1.545560e-6
GO:0032387	negative regulation of intracellular transport	1.590452e-6
GO:0008285	negative regulation of cell proliferation	1.605712e-6
GO:0006807	nitrogen compound metabolic process	1.656897e-6
GO:0045621	positive regulation of lymphocyte differentiation	1.729945e-6
GO:0022407	regulation of cell-cell adhesion	1.855578e-6
GO:0009890	negative regulation of biosynthetic process	1.983373e-6
GO:0043900	regulation of multi-organism process	2.039005e-6
GO:0045595	regulation of cell differentiation	2.109301e-6
GO:0034641	cellular nitrogen compound metabolic process	2.171498e-6
GO:0019882	antigen processing and presentation	2.265888e-6
GO:0048598	embryonic morphogenesis	2.285455e-6
GO:0000117	regulation of transcription involved in G2/M-phase of mitotic cell cycle	2.309321e-6
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	2.309321e-6
GO:0046824	positive regulation of nucleocytoplasmic transport	2.390215e-6
GO:0051649	establishment of localization in cell	2.504434e-6
GO:0010629	negative regulation of gene expression	2.605328e-6
GO:0071103	DNA conformation change	2.618496e-6
GO:0023051	regulation of signaling	2.657976e-6
GO:0071779	G1/S transition checkpoint	2.672938e-6
GO:0051253	negative regulation of RNA metabolic process	2.693681e-6
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	2.725334e-6
GO:0009954	proximal/distal pattern formation	2.877578e-6
GO:0001771	immunological synapse formation	2.920254e-6
GO:0003012	muscle system process	2.953352e-6
GO:0006605	protein targeting	2.988690e-6
GO:0044267	cellular protein metabolic process	3.093272e-6
GO:0010883	regulation of lipid storage	3.141867e-6
GO:0010717	regulation of epithelial to mesenchymal transition	3.304306e-6
GO:0000381	regulation of alternative nuclear mRNA splicing, via spliceosome	3.409899e-6
GO:0006915	apoptosis	3.455418e-6
GO:0048769	sarcomerogenesis	3.662660e-6
GO:0031575	mitotic cell cycle G1/S transition checkpoint	4.159265e-6
GO:0030595	leukocyte chemotaxis	4.188485e-6
GO:0045892	negative regulation of transcription, DNA-dependent	4.371355e-6
GO:0010648	negative regulation of cell communication	4.488195e-6
GO:0033962	cytoplasmic mRNA processing body assembly	4.667005e-6
GO:0048585	negative regulation of response to stimulus	4.753847e-6
GO:0007049	cell cycle	4.779241e-6
GO:0043412	macromolecule modification	4.956295e-6
GO:0048739	cardiac muscle fiber development	5.130126e-6
GO:0015031	protein transport	5.183719e-6
GO:0009083	branched chain family amino acid catabolic process	5.229994e-6
GO:0000904	cell morphogenesis involved in differentiation	5.310799e-6
GO:0008584	male gonad development	5.503323e-6
GO:0080090	regulation of primary metabolic process	5.567751e-6
GO:0023057	negative regulation of signaling	5.970584e-6
GO:0010157	response to chlorate	5.972591e-6
GO:0044419	interspecies interaction between organisms	6.263999e-6
GO:0046637	regulation of alpha-beta T cell differentiation	6.508558e-6
GO:0050776	regulation of immune response	6.543517e-6
GO:0046632	alpha-beta T cell differentiation	6.641713e-6
GO:0000902	cell morphogenesis	6.685805e-6
GO:0006796	phosphate-containing compound metabolic process	6.894440e-6
GO:0048387	negative regulation of retinoic acid receptor signaling pathway	7.220855e-6
GO:0002831	regulation of response to biotic stimulus	7.633984e-6
GO:0040011	locomotion	7.797572e-6
GO:0031323	regulation of cellular metabolic process	8.456078e-6
GO:0051172	negative regulation of nitrogen compound metabolic process	8.687390e-6
GO:0070861	regulation of protein exit from endoplasmic reticulum	8.833853e-6
GO:0050727	regulation of inflammatory response	8.960284e-6
GO:0060255	regulation of macromolecule metabolic process	9.123103e-6
GO:0030593	neutrophil chemotaxis	9.282982e-6
GO:0043330	response to exogenous dsRNA	9.765467e-6
GO:0060341	regulation of cellular localization	1.013140e-5
GO:0048667	cell morphogenesis involved in neuron differentiation	1.033477e-5
GO:0051276	chromosome organization	1.036258e-5
GO:0060710	chorio-allantoic fusion	1.073925e-5
GO:0045746	negative regulation of Notch signaling pathway	1.079735e-5
GO:0050900	leukocyte migration	1.161004e-5
GO:0007275	multicellular organismal development	1.168235e-5
GO:0042536	negative regulation of tumor necrosis factor biosynthetic process	1.177460e-5
GO:0048538	thymus development	1.209391e-5
GO:0030155	regulation of cell adhesion	1.231342e-5
GO:0031175	neuron projection development	1.232033e-5
GO:0046689	response to mercury ion	1.245948e-5
GO:0071842	cellular component organization at cellular level	1.299992e-5
GO:0046638	positive regulation of alpha-beta T cell differentiation	1.300279e-5
GO:0032502	developmental process	1.310412e-5
GO:0006606	protein import into nucleus	1.335575e-5
GO:0046546	development of primary male sexual characteristics	1.336351e-5
GO:0008152	metabolic process	1.375666e-5
GO:0071930	negative regulation of transcription involved in G1/S phase of mitotic cell cycle	1.409830e-5
GO:0009968	negative regulation of signal transduction	1.415625e-5
GO:0040019	positive regulation of embryonic development	1.449446e-5
GO:0006338	chromatin remodeling	1.476678e-5
GO:0009987	cellular process	1.488223e-5
GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	1.498844e-5
GO:0002675	positive regulation of acute inflammatory response	1.520261e-5
GO:0046649	lymphocyte activation	1.528897e-5
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	1.571294e-5
GO:0019219	regulation of nucleobase-containing compound metabolic process	1.579429e-5
GO:0050878	regulation of body fluid levels	1.640652e-5
GO:0071841	cellular component organization or biogenesis at cellular level	1.640831e-5
GO:0050709	negative regulation of protein secretion	1.656491e-5
GO:0048856	anatomical structure development	1.721087e-5
GO:0060713	labyrinthine layer morphogenesis	1.774020e-5
GO:0071158	positive regulation of cell cycle arrest	1.782158e-5
GO:0019222	regulation of metabolic process	1.866412e-5
GO:0051252	regulation of RNA metabolic process	1.881161e-5
GO:0007076	mitotic chromosome condensation	1.941673e-5
GO:0006551	leucine metabolic process	1.965520e-5
GO:2000045	regulation of G1/S transition of mitotic cell cycle	2.087672e-5
GO:0006959	humoral immune response	2.132498e-5
GO:0009790	embryo development	2.179693e-5
GO:0051092	positive regulation of NF-kappaB transcription factor activity	2.210800e-5
GO:0001658	branching involved in ureteric bud morphogenesis	2.216809e-5
GO:0042036	negative regulation of cytokine biosynthetic process	2.268858e-5
GO:0014048	regulation of glutamate secretion	2.297409e-5
GO:0007409	axonogenesis	2.450957e-5
GO:0033036	macromolecule localization	2.454816e-5
GO:0017038	protein import	2.466341e-5
GO:0060022	hard palate development	2.512967e-5
GO:0006418	tRNA aminoacylation for protein translation	2.653780e-5
GO:0045184	establishment of protein localization	2.665619e-5
GO:0045619	regulation of lymphocyte differentiation	2.672937e-5
GO:0002439	chronic inflammatory response to antigenic stimulus	2.674203e-5
GO:0010470	regulation of gastrulation	2.755209e-5
GO:0060343	trabecula formation	2.814712e-5
GO:0048812	neuron projection morphogenesis	2.831375e-5
GO:0006880	intracellular sequestering of iron ion	2.879274e-5
GO:0009123	nucleoside monophosphate metabolic process	2.921505e-5
GO:0014012	peripheral nervous system axon regeneration	2.946929e-5
GO:0031134	sister chromatid biorientation	2.974576e-5
GO:0051170	nuclear import	3.140234e-5
GO:0044264	cellular polysaccharide metabolic process	3.230750e-5
GO:0019538	protein metabolic process	3.331207e-5
GO:0051648	vesicle localization	3.424154e-5
GO:0070265	necrotic cell death	3.488302e-5
GO:0002686	negative regulation of leukocyte migration	3.579057e-5
GO:0061383	trabecula morphogenesis	3.653448e-5
GO:0048699	generation of neurons	3.725739e-5
GO:0045058	T cell selection	3.754474e-5
GO:0007411	axon guidance	3.763006e-5
GO:0043331	response to dsRNA	3.939185e-5
GO:0006936	muscle contraction	4.019528e-5
GO:0071934	thiamine transmembrane transport	4.034021e-5
GO:0006334	nucleosome assembly	4.245368e-5
GO:0007052	mitotic spindle organization	4.274996e-5
GO:0000060	protein import into nucleus, translocation	4.370682e-5
GO:0032100	positive regulation of appetite	4.485984e-5
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	4.554315e-5
GO:0034762	regulation of transmembrane transport	4.596379e-5
GO:0060675	ureteric bud morphogenesis	4.649500e-5
GO:0042113	B cell activation	4.689921e-5
GO:0006259	DNA metabolic process	4.847085e-5
GO:0045321	leukocyte activation	4.856176e-5
GO:0060429	epithelium development	4.942983e-5
GO:0060676	ureteric bud formation	4.948542e-5
GO:0009615	response to virus	5.130043e-5
GO:0071459	protein localization to chromosome, centromeric region	5.251210e-5
GO:0021997	neural plate axis specification	5.251210e-5
GO:0045785	positive regulation of cell adhesion	5.317882e-5
GO:0010556	regulation of macromolecule biosynthetic process	5.361226e-5
GO:0016051	carbohydrate biosynthetic process	5.508961e-5
GO:0042307	positive regulation of protein import into nucleus	5.512920e-5
GO:0048676	axon extension involved in development	5.648391e-5
GO:0006333	chromatin assembly or disassembly	5.843720e-5
GO:0034088	maintenance of mitotic sister chromatid cohesion	5.944034e-5
GO:0010467	gene expression	5.972816e-5
GO:0008104	protein localization	6.077222e-5
GO:0051171	regulation of nitrogen compound metabolic process	6.155003e-5
GO:0031349	positive regulation of defense response	6.220585e-5
GO:0006383	transcription from RNA polymerase III promoter	6.261088e-5
GO:0005978	glycogen biosynthetic process	6.323425e-5
GO:0006486	protein glycosylation	6.366578e-5
GO:0018279	protein N-linked glycosylation via asparagine	6.464312e-5
GO:0008219	cell death	6.634093e-5
GO:0072395	signal transduction involved in cell cycle checkpoint	6.722103e-5
GO:0009967	positive regulation of signal transduction	6.731722e-5
GO:0050778	positive regulation of immune response	7.091026e-5
GO:0006487	protein N-linked glycosylation	7.140704e-5
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	7.198924e-5
GO:0042278	purine nucleoside metabolic process	7.393147e-5
GO:0045995	regulation of embryonic development	7.663489e-5
GO:0016265	death	7.734306e-5
GO:0006355	regulation of transcription, DNA-dependent	7.898310e-5
GO:0010743	regulation of macrophage derived foam cell differentiation	8.087893e-5
GO:0071840	cellular component organization or biogenesis	8.176100e-5
GO:0050702	interleukin-1 beta secretion	8.348074e-5
GO:0022604	regulation of cell morphogenesis	8.393871e-5
GO:0051592	response to calcium ion	8.540873e-5
GO:0000819	sister chromatid segregation	9.064676e-5
GO:0006913	nucleocytoplasmic transport	9.505785e-5
GO:0051050	positive regulation of transport	9.705268e-5
GO:0050793	regulation of developmental process	9.768388e-5
GO:0021987	cerebral cortex development	1.019770e-4
GO:0051704	multi-organism process	1.022124e-4
GO:0050652	dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	1.026906e-4
GO:0071320	cellular response to cAMP	1.034850e-4
GO:0009100	glycoprotein metabolic process	1.042594e-4
GO:0007093	mitotic cell cycle checkpoint	1.052156e-4
GO:0072422	signal transduction involved in DNA damage checkpoint	1.052715e-4
GO:0010559	regulation of glycoprotein biosynthetic process	1.052890e-4
GO:0008593	regulation of Notch signaling pathway	1.066773e-4
GO:2000112	regulation of cellular macromolecule biosynthetic process	1.086841e-4
GO:0048858	cell projection morphogenesis	1.100576e-4
GO:0034622	cellular macromolecular complex assembly	1.101987e-4
GO:0006351	transcription, DNA-dependent	1.108490e-4
GO:0006376	mRNA splice site selection	1.123810e-4
GO:0042345	regulation of NF-kappaB import into nucleus	1.155737e-4
GO:0006768	biotin metabolic process	1.168942e-4
GO:0051222	positive regulation of protein transport	1.180856e-4
GO:0031497	chromatin assembly	1.212683e-4
GO:0072404	signal transduction involved in G1/S transition checkpoint	1.221594e-4
GO:0000398	nuclear mRNA splicing, via spliceosome	1.227139e-4
GO:0034728	nucleosome organization	1.250315e-4
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	1.270776e-4
GO:0032109	positive regulation of response to nutrient levels	1.272702e-4
GO:0044140	negative regulation of growth of symbiont on or near host surface	1.291653e-4
GO:0007338	single fertilization	1.302534e-4
GO:0032273	positive regulation of protein polymerization	1.315476e-4
GO:0046661	male sex differentiation	1.333554e-4
GO:0010627	regulation of intracellular protein kinase cascade	1.337136e-4
GO:0006886	intracellular protein transport	1.357586e-4
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	1.358891e-4
GO:0000271	polysaccharide biosynthetic process	1.377338e-4
GO:0002684	positive regulation of immune system process	1.386592e-4
GO:0005976	polysaccharide metabolic process	1.387133e-4
GO:0033363	secretory granule organization	1.398815e-4
GO:0010718	positive regulation of epithelial to mesenchymal transition	1.416952e-4
GO:0051169	nuclear transport	1.428504e-4
GO:2000104	negative regulation of DNA-dependent DNA replication	1.440632e-4
GO:0070085	glycosylation	1.442430e-4
GO:0016043	cellular component organization	1.443136e-4
GO:0009101	glycoprotein biosynthetic process	1.450387e-4
GO:0046634	regulation of alpha-beta T cell activation	1.458096e-4
GO:0010647	positive regulation of cell communication	1.461478e-4
GO:0000070	mitotic sister chromatid segregation	1.476286e-4
GO:0045409	negative regulation of interleukin-6 biosynthetic process	1.489813e-4
GO:0001649	osteoblast differentiation	1.490732e-4
GO:0051290	protein heterotetramerization	1.495580e-4
GO:0043620	regulation of DNA-dependent transcription in response to stress	1.502768e-4
GO:0045582	positive regulation of T cell differentiation	1.506022e-4
GO:0090317	negative regulation of intracellular protein transport	1.529996e-4
GO:0015721	bile acid and bile salt transport	1.546103e-4
GO:0044237	cellular metabolic process	1.547228e-4
GO:0045580	regulation of T cell differentiation	1.550070e-4
GO:0046777	protein autophosphorylation	1.560466e-4
GO:0042921	glucocorticoid receptor signaling pathway	1.570758e-4
GO:0031326	regulation of cellular biosynthetic process	1.589094e-4
GO:0060118	vestibular receptor cell development	1.641974e-4
GO:0050707	regulation of cytokine secretion	1.654585e-4
GO:0042990	regulation of transcription factor import into nucleus	1.664342e-4
GO:0050728	negative regulation of inflammatory response	1.672264e-4
GO:0048747	muscle fiber development	1.696519e-4
GO:0032774	RNA biosynthetic process	1.700254e-4
GO:0034621	cellular macromolecular complex subunit organization	1.804764e-4
GO:0002757	immune response-activating signal transduction	1.822631e-4
GO:2000026	regulation of multicellular organismal development	1.826735e-4
GO:0048565	digestive tract development	1.828022e-4
GO:0043039	tRNA aminoacylation	1.842875e-4
GO:0010468	regulation of gene expression	1.857997e-4
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.898670e-4
GO:0015855	pyrimidine base transport	1.904192e-4
GO:0050798	activated T cell proliferation	1.921652e-4
GO:0023056	positive regulation of signaling	1.930834e-4
GO:0022008	neurogenesis	1.962304e-4
GO:0002683	negative regulation of immune system process	1.962941e-4
GO:0010041	response to iron(III) ion	1.962978e-4
GO:0032252	secretory granule localization	1.990345e-4
GO:0002429	immune response-activating cell surface receptor signaling pathway	2.000275e-4
GO:0022603	regulation of anatomical structure morphogenesis	2.020547e-4
GO:0009214	cyclic nucleotide catabolic process	2.032550e-4
GO:0010769	regulation of cell morphogenesis involved in differentiation	2.053827e-4
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	2.055659e-4
GO:0033364	mast cell secretory granule organization	2.079268e-4
GO:0043368	positive T cell selection	2.079292e-4
GO:0010557	positive regulation of macromolecule biosynthetic process	2.092630e-4
GO:0034764	positive regulation of transmembrane transport	2.122929e-4
GO:0022409	positive regulation of cell-cell adhesion	2.166747e-4
GO:0006970	response to osmotic stress	2.204048e-4
GO:0009125	nucleoside monophosphate catabolic process	2.225512e-4
GO:0001952	regulation of cell-matrix adhesion	2.238422e-4
GO:0046128	purine ribonucleoside metabolic process	2.239241e-4
GO:0051179	localization	2.245390e-4
GO:0042771	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis	2.246873e-4
GO:0033692	cellular polysaccharide biosynthetic process	2.251984e-4
GO:0014866	skeletal myofibril assembly	2.253038e-4
GO:0070252	actin-mediated cell contraction	2.261167e-4
GO:0010288	response to lead ion	2.267016e-4
GO:0002520	immune system development	2.277161e-4
GO:0060555	induction of necroptosis by extracellular signals	2.279550e-4
GO:0002431	Fc receptor mediated stimulatory signaling pathway	2.298160e-4
GO:0001805	positive regulation of type III hypersensitivity	2.298160e-4
GO:0033554	cellular response to stress	2.312302e-4
GO:0019227	neuronal action potential propagation	2.347445e-4
GO:0065004	protein-DNA complex assembly	2.448381e-4
GO:0008629	induction of apoptosis by intracellular signals	2.489422e-4
GO:0009566	fertilization	2.493926e-4
GO:0014889	muscle atrophy	2.568403e-4
GO:0050866	negative regulation of cell activation	2.581333e-4
GO:0030049	muscle filament sliding	2.614691e-4
GO:0030030	cell projection organization	2.619796e-4
GO:0000084	S phase of mitotic cell cycle	2.664556e-4
GO:0060558	regulation of calcidiol 1-monooxygenase activity	2.685935e-4
GO:0070417	cellular response to cold	2.694098e-4
GO:0014049	positive regulation of glutamate secretion	2.694538e-4
GO:0009889	regulation of biosynthetic process	2.705256e-4
GO:0006086	acetyl-CoA biosynthetic process from pyruvate	2.716027e-4
GO:0045087	innate immune response	2.776072e-4
GO:0048024	regulation of nuclear mRNA splicing, via spliceosome	2.824105e-4
GO:0006198	cAMP catabolic process	2.824105e-4
GO:0033365	protein localization to organelle	2.907542e-4
GO:0007521	muscle cell fate determination	3.103772e-4
GO:0032611	interleukin-1 beta production	3.113435e-4
GO:0050691	regulation of defense response to virus by host	3.157190e-4
GO:0002764	immune response-regulating signaling pathway	3.159603e-4
GO:0005977	glycogen metabolic process	3.160250e-4
GO:0042997	negative regulation of Golgi to plasma membrane protein transport	3.248614e-4
GO:0001692	histamine metabolic process	3.248614e-4
GO:0031348	negative regulation of defense response	3.340476e-4
GO:0006335	DNA replication-dependent nucleosome assembly	3.350014e-4
GO:0030518	steroid hormone receptor signaling pathway	3.379654e-4
GO:0002437	inflammatory response to antigenic stimulus	3.393649e-4
GO:0016477	cell migration	3.467112e-4
GO:0032501	multicellular organismal process	3.481155e-4
GO:0060100	positive regulation of phagocytosis, engulfment	3.545690e-4
GO:0032990	cell part morphogenesis	3.581315e-4
GO:0034116	positive regulation of heterotypic cell-cell adhesion	3.600200e-4
GO:0000375	RNA splicing, via transesterification reactions	3.601388e-4
GO:0019836	hemolysis by symbiont of host erythrocytes	3.636253e-4
GO:0000272	polysaccharide catabolic process	3.737203e-4
GO:0009057	macromolecule catabolic process	3.773647e-4
GO:0034114	regulation of heterotypic cell-cell adhesion	3.788220e-4
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	3.788220e-4
GO:0045073	regulation of chemokine biosynthetic process	3.793134e-4
GO:0033158	regulation of protein import into nucleus, translocation	3.829763e-4
GO:0031099	regeneration	3.863987e-4
GO:0002768	immune response-regulating cell surface receptor signaling pathway	3.888781e-4
GO:0046907	intracellular transport	3.960153e-4
GO:0010811	positive regulation of cell-substrate adhesion	4.101674e-4
GO:0071922	regulation of cohesin localization to chromatin	4.181686e-4
GO:0033033	negative regulation of myeloid cell apoptosis	4.188657e-4
GO:0032509	endosome transport via multivesicular body sorting pathway	4.195590e-4
GO:0002286	T cell activation involved in immune response	4.247766e-4
GO:0070734	histone H3-K27 methylation	4.278064e-4
GO:0010243	response to organic nitrogen	4.298288e-4
GO:0071363	cellular response to growth factor stimulus	4.303860e-4
GO:0051052	regulation of DNA metabolic process	4.362243e-4
GO:0006663	platelet activating factor biosynthetic process	4.372328e-4
GO:0009988	cell-cell recognition	4.386730e-4
GO:0000279	M phase	4.415598e-4
GO:0051320	S phase	4.458233e-4
GO:0046827	positive regulation of protein export from nucleus	4.480374e-4
GO:0045879	negative regulation of smoothened signaling pathway	4.483848e-4
GO:0021798	forebrain dorsal/ventral pattern formation	4.494235e-4
GO:0006325	chromatin organization	4.531948e-4
GO:0034613	cellular protein localization	4.551692e-4
GO:0006261	DNA-dependent DNA replication	4.566148e-4
GO:0050767	regulation of neurogenesis	4.594093e-4
GO:0000216	M/G1 transition of mitotic cell cycle	4.623380e-4
GO:0031102	neuron projection regeneration	4.634551e-4
GO:0007015	actin filament organization	4.643565e-4
GO:0002576	platelet degranulation	4.644263e-4
GO:0050690	regulation of defense response to virus by virus	4.656518e-4
GO:0031103	axon regeneration	4.667708e-4
GO:0048666	neuron development	4.782263e-4
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	4.787325e-4
GO:0046635	positive regulation of alpha-beta T cell activation	4.798178e-4
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	4.805465e-4
GO:0010740	positive regulation of intracellular protein kinase cascade	4.831768e-4
GO:0070727	cellular macromolecule localization	4.854367e-4
GO:0001957	intramembranous ossification	4.891736e-4
GO:0071447	cellular response to hydroperoxide	4.905958e-4
GO:0044249	cellular biosynthetic process	4.906580e-4
GO:0071824	protein-DNA complex subunit organization	4.910994e-4
GO:0043297	apical junction assembly	4.919930e-4
GO:0032314	regulation of Rac GTPase activity	4.932323e-4
GO:0048732	gland development	4.951319e-4
GO:0050684	regulation of mRNA processing	4.957305e-4
GO:0002740	negative regulation of cytokine secretion involved in immune response	5.024736e-4
GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint	5.027477e-4
GO:0002218	activation of innate immune response	5.062368e-4
GO:0061088	regulation of sequestering of zinc ion	5.092393e-4
GO:0001655	urogenital system development	5.129741e-4
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	5.164633e-4
GO:0000209	protein polyubiquitination	5.197855e-4
GO:0032446	protein modification by small protein conjugation	5.222259e-4
GO:0060443	mammary gland morphogenesis	5.253973e-4
GO:0070848	response to growth factor stimulus	5.282186e-4
GO:0060346	bone trabecula formation	5.429780e-4
GO:0051049	regulation of transport	5.494023e-4
GO:0051902	negative regulation of mitochondrial depolarization	5.526385e-4
GO:0019303	D-ribose catabolic process	5.531635e-4
GO:0015718	monocarboxylic acid transport	5.652354e-4
GO:0048534	hemopoietic or lymphoid organ development	5.659709e-4
GO:0046058	cAMP metabolic process	5.662517e-4
GO:0007163	establishment or maintenance of cell polarity	5.747865e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0050794	regulation of cellular process	2.611192e-14
GO:0065007	biological regulation	4.435220e-14
GO:0050789	regulation of biological process	8.527841e-14
GO:0048523	negative regulation of cellular process	4.287332e-13
GO:0006950	response to stress	8.068375e-13
GO:0048518	positive regulation of biological process	2.115975e-12
GO:0048519	negative regulation of biological process	2.303596e-12
GO:0050896	response to stimulus	4.773389e-11
GO:0044249	cellular biosynthetic process	9.948191e-10
GO:0002475	antigen processing and presentation via MHC class Ib	4.334409e-9
GO:0008207	C21-steroid hormone metabolic process	4.379104e-9
GO:0032501	multicellular organismal process	1.038201e-8
GO:0048522	positive regulation of cellular process	1.194748e-8
GO:0010467	gene expression	1.669093e-8
GO:0051883	killing of cells in other organism involved in symbiotic interaction	2.014620e-8
GO:0034645	cellular macromolecule biosynthetic process	2.382692e-8
GO:0031640	killing of cells of other organism	2.858457e-8
GO:0090304	nucleic acid metabolic process	2.960053e-8
GO:0006139	nucleobase-containing compound metabolic process	3.270738e-8
GO:0008285	negative regulation of cell proliferation	3.470652e-8
GO:0009893	positive regulation of metabolic process	5.187243e-8
GO:0051646	mitochondrion localization	5.763096e-8
GO:0009058	biosynthetic process	7.315748e-8
GO:0001906	cell killing	7.509683e-8
GO:0008211	glucocorticoid metabolic process	9.485282e-8
GO:0010604	positive regulation of macromolecule metabolic process	1.005171e-7
GO:0048146	positive regulation of fibroblast proliferation	1.073767e-7
GO:0009059	macromolecule biosynthetic process	1.384513e-7
GO:0051716	cellular response to stimulus	1.527362e-7
GO:0016070	RNA metabolic process	1.612396e-7
GO:0031325	positive regulation of cellular metabolic process	2.351912e-7
GO:0006700	C21-steroid hormone biosynthetic process	2.607880e-7
GO:0010468	regulation of gene expression	2.688816e-7
GO:0060620	regulation of cholesterol import	3.009540e-7
GO:0051640	organelle localization	3.044735e-7
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	3.240294e-7
GO:0021773	striatal medium spiny neuron differentiation	4.721085e-7
GO:0019222	regulation of metabolic process	4.975532e-7
GO:0030154	cell differentiation	5.183696e-7
GO:0060621	negative regulation of cholesterol import	5.437595e-7
GO:0007275	multicellular organismal development	6.504167e-7
GO:0032502	developmental process	6.722687e-7
GO:0060255	regulation of macromolecule metabolic process	7.523844e-7
GO:0043368	positive T cell selection	7.982893e-7
GO:0050710	negative regulation of cytokine secretion	8.094111e-7
GO:0051707	response to other organism	9.696753e-7
GO:0031324	negative regulation of cellular metabolic process	1.009837e-6
GO:0031915	positive regulation of synaptic plasticity	1.082275e-6
GO:0009607	response to biotic stimulus	1.212090e-6
GO:0006704	glucocorticoid biosynthetic process	1.222958e-6
GO:0006807	nitrogen compound metabolic process	1.284697e-6
GO:0043170	macromolecule metabolic process	1.637571e-6
GO:0044260	cellular macromolecule metabolic process	1.674820e-6
GO:0070848	response to growth factor stimulus	1.813913e-6
GO:0009892	negative regulation of metabolic process	2.084342e-6
GO:0010837	regulation of keratinocyte proliferation	2.088372e-6
GO:0031323	regulation of cellular metabolic process	2.156388e-6
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	2.160078e-6
GO:0048007	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	2.431943e-6
GO:0034641	cellular nitrogen compound metabolic process	2.470860e-6
GO:0019884	antigen processing and presentation of exogenous antigen	2.533287e-6
GO:0048869	cellular developmental process	2.628399e-6
GO:0090288	negative regulation of cellular response to growth factor stimulus	2.892953e-6
GO:0042592	homeostatic process	2.914828e-6
GO:0006020	inositol metabolic process	2.962610e-6
GO:0009987	cellular process	3.381679e-6
GO:0042127	regulation of cell proliferation	3.559413e-6
GO:0048583	regulation of response to stimulus	3.709305e-6
GO:0006633	fatty acid biosynthetic process	4.118682e-6
GO:0050795	regulation of behavior	4.533150e-6
GO:0031077	post-embryonic camera-type eye development	4.719224e-6
GO:0045595	regulation of cell differentiation	5.345770e-6
GO:0042446	hormone biosynthetic process	5.697311e-6
GO:0006952	defense response	5.743455e-6
GO:0030216	keratinocyte differentiation	5.813459e-6
GO:0051657	maintenance of organelle location	6.098751e-6
GO:0046340	diacylglycerol catabolic process	6.850224e-6
GO:0031401	positive regulation of protein modification process	7.004670e-6
GO:0065008	regulation of biological quality	7.725612e-6
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	7.725921e-6
GO:0033153	T cell receptor V(D)J recombination	7.826746e-6
GO:0032844	regulation of homeostatic process	8.183464e-6
GO:0048145	regulation of fibroblast proliferation	8.316939e-6
GO:0001516	prostaglandin biosynthetic process	9.044191e-6
GO:0001775	cell activation	9.047724e-6
GO:0002376	immune system process	9.781185e-6
GO:0006656	phosphatidylcholine biosynthetic process	9.880714e-6
GO:0000381	regulation of alternative nuclear mRNA splicing, via spliceosome	1.025196e-5
GO:0048520	positive regulation of behavior	1.074185e-5
GO:0008593	regulation of Notch signaling pathway	1.288888e-5
GO:0044238	primary metabolic process	1.346079e-5
GO:0010989	negative regulation of low-density lipoprotein particle clearance	1.368293e-5
GO:0009913	epidermal cell differentiation	1.388796e-5
GO:0006412	translation	1.411257e-5
GO:0010605	negative regulation of macromolecule metabolic process	1.483804e-5
GO:0042745	circadian sleep/wake cycle	1.569090e-5
GO:0019219	regulation of nucleobase-containing compound metabolic process	1.589143e-5
GO:0051659	maintenance of mitochondrion location	1.595152e-5
GO:0007219	Notch signaling pathway	1.617040e-5
GO:0043588	skin development	1.653078e-5
GO:0022410	circadian sleep/wake cycle process	1.739570e-5
GO:0003334	keratinocyte development	1.744625e-5
GO:0051171	regulation of nitrogen compound metabolic process	1.758926e-5
GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent	1.777423e-5
GO:0034380	high-density lipoprotein particle assembly	1.839550e-5
GO:0044403	symbiosis, encompassing mutualism through parasitism	1.855690e-5
GO:0023052	signaling	1.873853e-5
GO:0010557	positive regulation of macromolecule biosynthetic process	1.913010e-5
GO:0002331	pre-B cell allelic exclusion	1.924420e-5
GO:0033151	V(D)J recombination	1.941468e-5
GO:2000104	negative regulation of DNA-dependent DNA replication	1.945189e-5
GO:0051704	multi-organism process	1.968538e-5
GO:0043589	skin morphogenesis	2.445425e-5
GO:0090209	negative regulation of triglyceride metabolic process	2.452178e-5
GO:0002682	regulation of immune system process	2.465764e-5
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	2.477490e-5
GO:0030237	female sex determination	2.554203e-5
GO:0007165	signal transduction	2.583889e-5
GO:0061002	negative regulation of dendritic spine morphogenesis	2.588336e-5
GO:0001676	long-chain fatty acid metabolic process	2.762614e-5
GO:0006360	transcription from RNA polymerase I promoter	2.882336e-5
GO:0014003	oligodendrocyte development	2.981211e-5
GO:0010556	regulation of macromolecule biosynthetic process	3.029291e-5
GO:0007154	cell communication	3.066341e-5
GO:0090362	positive regulation of platelet-derived growth factor production	3.078328e-5
GO:0090336	positive regulation of brown fat cell differentiation	3.078328e-5
GO:0070831	basement membrane assembly	3.078328e-5
GO:0090271	positive regulation of fibroblast growth factor production	3.078328e-5
GO:0002740	negative regulation of cytokine secretion involved in immune response	3.372436e-5
GO:0035691	macrophage migration inhibitory factor signaling pathway	3.460192e-5
GO:0030538	embryonic genitalia morphogenesis	3.524138e-5
GO:0071363	cellular response to growth factor stimulus	3.601512e-5
GO:0035270	endocrine system development	3.773201e-5
GO:0050709	negative regulation of protein secretion	3.868582e-5
GO:0010628	positive regulation of gene expression	3.891777e-5
GO:0030514	negative regulation of BMP signaling pathway	4.044574e-5
GO:0009891	positive regulation of biosynthetic process	4.101957e-5
GO:0051173	positive regulation of nitrogen compound metabolic process	4.266596e-5
GO:0009628	response to abiotic stimulus	4.279305e-5
GO:0032438	melanosome organization	4.348804e-5
GO:0006367	transcription initiation from RNA polymerase II promoter	4.375192e-5
GO:0031326	regulation of cellular biosynthetic process	4.378518e-5
GO:0030728	ovulation	4.455095e-5
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	4.476988e-5
GO:0048731	system development	4.531814e-5
GO:0035411	catenin import into nucleus	4.595305e-5
GO:0002739	regulation of cytokine secretion involved in immune response	4.649765e-5
GO:0006418	tRNA aminoacylation for protein translation	4.691372e-5
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	4.809847e-5
GO:0090287	regulation of cellular response to growth factor stimulus	4.875435e-5
GO:0031328	positive regulation of cellular biosynthetic process	4.912007e-5
GO:0042048	olfactory behavior	5.024195e-5
GO:0048513	organ development	5.272436e-5
GO:0019836	hemolysis by symbiont of host erythrocytes	5.847443e-5
GO:0045746	negative regulation of Notch signaling pathway	5.953267e-5
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	6.264730e-5
GO:2000173	negative regulation of branching morphogenesis of a nerve	6.272808e-5
GO:0042946	glucoside transport	6.272808e-5
GO:0014012	peripheral nervous system axon regeneration	6.346928e-5
GO:0048013	ephrin receptor signaling pathway	6.355442e-5
GO:0043434	response to peptide hormone stimulus	6.665736e-5
GO:0019882	antigen processing and presentation	7.027401e-5
GO:0002830	positive regulation of type 2 immune response	7.111634e-5
GO:0051873	killing by host of symbiont cells	7.111634e-5
GO:0010941	regulation of cell death	7.503768e-5
GO:0009750	response to fructose stimulus	7.511326e-5
GO:0030855	epithelial cell differentiation	7.775682e-5
GO:0031641	regulation of myelination	7.921848e-5
GO:2000112	regulation of cellular macromolecule biosynthetic process	7.942192e-5
GO:0045833	negative regulation of lipid metabolic process	8.116783e-5
GO:0051252	regulation of RNA metabolic process	8.265781e-5
GO:0051894	positive regulation of focal adhesion assembly	8.400961e-5
GO:0060907	positive regulation of macrophage cytokine production	8.426271e-5
GO:0045026	plasma membrane fusion	8.590364e-5
GO:0048878	chemical homeostasis	8.631908e-5
GO:0046032	ADP catabolic process	8.660090e-5
GO:0046709	IDP catabolic process	8.660090e-5
GO:0043069	negative regulation of programmed cell death	9.231640e-5
GO:0030097	hemopoiesis	9.263358e-5
GO:0045321	leukocyte activation	9.403194e-5
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	9.643342e-5
GO:0060548	negative regulation of cell death	9.962284e-5
GO:0051224	negative regulation of protein transport	9.989311e-5
GO:0008616	queuosine biosynthetic process	9.998985e-5
GO:0045576	mast cell activation	1.016112e-4
GO:0006636	unsaturated fatty acid biosynthetic process	1.023467e-4
GO:0009889	regulation of biosynthetic process	1.051131e-4
GO:0051239	regulation of multicellular organismal process	1.053508e-4
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	1.076879e-4
GO:0048512	circadian behavior	1.078433e-4
GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	1.085475e-4
GO:0060014	granulosa cell differentiation	1.127555e-4
GO:0002700	regulation of production of molecular mediator of immune response	1.132489e-4
GO:0045893	positive regulation of transcription, DNA-dependent	1.148723e-4
GO:0048002	antigen processing and presentation of peptide antigen	1.152196e-4
GO:0048856	anatomical structure development	1.156964e-4
GO:0003382	epithelial cell morphogenesis	1.165879e-4
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	1.264848e-4
GO:0048024	regulation of nuclear mRNA splicing, via spliceosome	1.333853e-4
GO:0008354	germ cell migration	1.342975e-4
GO:0050711	negative regulation of interleukin-1 secretion	1.348540e-4
GO:0034754	cellular hormone metabolic process	1.351392e-4
GO:0060341	regulation of cellular localization	1.376166e-4
GO:0032270	positive regulation of cellular protein metabolic process	1.412804e-4
GO:0080090	regulation of primary metabolic process	1.423890e-4
GO:0045187	regulation of circadian sleep/wake cycle, sleep	1.458203e-4
GO:0050853	B cell receptor signaling pathway	1.513759e-4
GO:0009191	ribonucleoside diphosphate catabolic process	1.546765e-4
GO:0051055	negative regulation of lipid biosynthetic process	1.546999e-4
GO:0090329	regulation of DNA-dependent DNA replication	1.553676e-4
GO:0042772	DNA damage response, signal transduction resulting in transcription	1.558001e-4
GO:0002520	immune system development	1.565162e-4
GO:0050713	negative regulation of interleukin-1 beta secretion	1.640764e-4
GO:0009968	negative regulation of signal transduction	1.662158e-4
GO:0051254	positive regulation of RNA metabolic process	1.698900e-4
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	1.714603e-4
GO:0043067	regulation of programmed cell death	1.827356e-4
GO:0061017	hepatoblast differentiation	1.916008e-4
GO:0002820	negative regulation of adaptive immune response	1.919475e-4
GO:0019725	cellular homeostasis	2.066032e-4
GO:0051299	centrosome separation	2.114288e-4
GO:0048585	negative regulation of response to stimulus	2.175124e-4
GO:0046853	inositol or phosphatidylinositol phosphorylation	2.237447e-4
GO:0060695	negative regulation of cholesterol transporter activity	2.237447e-4
GO:0021957	corticospinal tract morphogenesis	2.237447e-4
GO:0015759	beta-glucoside transport	2.237447e-4
GO:0008057	eye pigment granule organization	2.237447e-4
GO:0050930	induction of positive chemotaxis	2.246043e-4
GO:0006310	DNA recombination	2.324413e-4
GO:0009185	ribonucleoside diphosphate metabolic process	2.445797e-4
GO:0042221	response to chemical stimulus	2.509721e-4
GO:0051893	regulation of focal adhesion assembly	2.556720e-4
GO:0034629	cellular protein complex localization	2.561831e-4
GO:0051053	negative regulation of DNA metabolic process	2.565842e-4
GO:0043066	negative regulation of apoptosis	2.606580e-4
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	2.644019e-4
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.644019e-4
GO:0045081	negative regulation of interleukin-10 biosynthetic process	2.644282e-4
GO:0032252	secretory granule localization	2.663216e-4
GO:0019220	regulation of phosphate metabolic process	2.728337e-4
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	2.731093e-4
GO:0002200	somatic diversification of immune receptors	2.763919e-4
GO:0050801	ion homeostasis	2.766234e-4
GO:0046339	diacylglycerol metabolic process	2.773943e-4
GO:0042110	T cell activation	2.834639e-4
GO:0002428	antigen processing and presentation of peptide antigen via MHC class Ib	2.891301e-4
GO:0010033	response to organic substance	2.919470e-4
GO:0009617	response to bacterium	2.967031e-4
GO:0006873	cellular ion homeostasis	2.984444e-4
GO:0002702	positive regulation of production of molecular mediator of immune response	2.988960e-4
GO:0002707	negative regulation of lymphocyte mediated immunity	3.109439e-4
GO:0006357	regulation of transcription from RNA polymerase II promoter	3.176978e-4
GO:0031399	regulation of protein modification process	3.183269e-4
GO:0061011	hepatic duct development	3.184351e-4
GO:0023057	negative regulation of signaling	3.191941e-4
GO:0042703	menstruation	3.216188e-4
GO:0019101	female somatic sex determination	3.216188e-4
GO:0010725	regulation of primitive erythrocyte differentiation	3.216188e-4
GO:0006355	regulation of transcription, DNA-dependent	3.230538e-4
GO:0048625	myoblast cell fate commitment	3.235915e-4
GO:0050926	regulation of positive chemotaxis	3.245759e-4
GO:0048753	pigment granule organization	3.300073e-4
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	3.322489e-4
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	3.325117e-4
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	3.357853e-4
GO:0007622	rhythmic behavior	3.532863e-4
GO:0051247	positive regulation of protein metabolic process	3.565751e-4
GO:0046456	icosanoid biosynthetic process	3.633844e-4
GO:0009890	negative regulation of biosynthetic process	3.699275e-4
GO:0042413	carnitine catabolic process	3.759866e-4
GO:0042758	long-chain fatty acid catabolic process	3.759866e-4
GO:0001920	negative regulation of receptor recycling	3.759866e-4
GO:0002478	antigen processing and presentation of exogenous peptide antigen	3.781869e-4
GO:0019953	sexual reproduction	3.798499e-4
GO:0048534	hemopoietic or lymphoid organ development	3.809258e-4
GO:0001932	regulation of protein phosphorylation	3.827949e-4
GO:0046394	carboxylic acid biosynthetic process	3.875840e-4
GO:0033627	cell adhesion mediated by integrin	3.904788e-4
GO:0043534	blood vessel endothelial cell migration	3.983059e-4
GO:0043457	regulation of cellular respiration	4.008517e-4
GO:0031327	negative regulation of cellular biosynthetic process	4.036992e-4
GO:0009303	rRNA transcription	4.241136e-4
GO:0048010	vascular endothelial growth factor receptor signaling pathway	4.283861e-4
GO:0030510	regulation of BMP signaling pathway	4.301413e-4
GO:0032774	RNA biosynthetic process	4.305682e-4
GO:0010897	negative regulation of triglyceride catabolic process	4.363240e-4
GO:0010987	negative regulation of high-density lipoprotein particle clearance	4.363240e-4
GO:0046621	negative regulation of organ growth	4.411738e-4
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	4.427458e-4
GO:0045058	T cell selection	4.459741e-4
GO:0050927	positive regulation of positive chemotaxis	4.462196e-4
GO:0007062	sister chromatid cohesion	4.506768e-4
GO:0031103	axon regeneration	4.613777e-4
GO:0007342	fusion of sperm to egg plasma membrane	4.644751e-4
GO:0032876	negative regulation of DNA endoreduplication	4.644751e-4
GO:0006970	response to osmotic stress	4.649104e-4
GO:0070541	response to platinum ion	4.713619e-4
GO:0009134	nucleoside diphosphate catabolic process	4.713619e-4
GO:0008610	lipid biosynthetic process	4.737046e-4
GO:0006351	transcription, DNA-dependent	4.926946e-4
GO:2000639	negative regulation of SREBP-mediated signaling pathway	4.938625e-4
GO:2000346	negative regulation of hepatocyte proliferation	4.938625e-4
GO:0007417	central nervous system development	5.026098e-4
GO:0006631	fatty acid metabolic process	5.070529e-4
GO:0008380	RNA splicing	5.157411e-4
GO:0008544	epidermis development	5.182550e-4
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	5.194277e-4
GO:0055082	cellular chemical homeostasis	5.195511e-4
GO:0051289	protein homotetramerization	5.346620e-4
GO:0022414	reproductive process	5.357980e-4
GO:0002064	epithelial cell development	5.377303e-4
GO:0033135	regulation of peptidyl-serine phosphorylation	5.499048e-4
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	5.600456e-4
GO:0006693	prostaglandin metabolic process	5.701473e-4
GO:0010558	negative regulation of macromolecule biosynthetic process	5.717977e-4
GO:0031503	protein complex localization	5.794247e-4
GO:0002906	negative regulation of mature B cell apoptosis	5.794247e-4
GO:0008152	metabolic process	6.045339e-4
GO:0006629	lipid metabolic process	6.165420e-4
GO:0032268	regulation of cellular protein metabolic process	6.362093e-4
GO:0007276	gamete generation	6.546999e-4
GO:0043129	surfactant homeostasis	6.607964e-4
GO:0006259	DNA metabolic process	6.714590e-4
GO:0032048	cardiolipin metabolic process	6.963423e-4
GO:0070904	transepithelial L-ascorbic acid transport	6.963656e-4
GO:0031647	regulation of protein stability	7.105791e-4
GO:0010935	regulation of macrophage cytokine production	7.116203e-4
GO:0048619	embryonic hindgut morphogenesis	7.116203e-4
GO:0031000	response to caffeine	7.124093e-4
GO:0051701	interaction with host	7.128465e-4
GO:0046031	ADP metabolic process	7.185951e-4
GO:0002521	leukocyte differentiation	7.237427e-4
GO:0021983	pituitary gland development	7.384938e-4
GO:0031398	positive regulation of protein ubiquitination	7.419113e-4
GO:0002718	regulation of cytokine production involved in immune response	7.490718e-4
GO:0007584	response to nutrient	7.517641e-4
GO:0042981	regulation of apoptosis	7.722721e-4
GO:0030033	microvillus assembly	7.742503e-4
GO:0033059	cellular pigmentation	7.767751e-4
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	7.971977e-4
GO:0045446	endothelial cell differentiation	8.072232e-4
GO:0072560	type B pancreatic cell maturation	8.099371e-4
GO:0031081	nuclear pore distribution	8.099371e-4
GO:0055065	metal ion homeostasis	8.149056e-4
GO:0042759	long-chain fatty acid biosynthetic process	8.362474e-4
GO:2000026	regulation of multicellular organismal development	8.371490e-4
GO:0033578	protein glycosylation in Golgi	8.418969e-4
GO:0060708	spongiotrophoblast differentiation	8.418969e-4
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	8.434127e-4
GO:0009636	response to toxin	8.609079e-4
GO:0051648	vesicle localization	8.677284e-4
GO:0071841	cellular component organization or biogenesis at cellular level	8.738939e-4
GO:0007409	axonogenesis	8.803353e-4
GO:0051085	chaperone mediated protein folding requiring cofactor	9.165071e-4
GO:0009966	regulation of signal transduction	9.409926e-4
GO:0032387	negative regulation of intracellular transport	9.446787e-4
GO:0045046	protein import into peroxisome membrane	9.619509e-4
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	9.662639e-4
GO:0007221	positive regulation of transcription of Notch receptor target	9.777738e-4
GO:0048584	positive regulation of response to stimulus	9.820543e-4
GO:0009181	purine ribonucleoside diphosphate catabolic process	9.875611e-4
GO:0045074	regulation of interleukin-10 biosynthetic process	9.992964e-4
GO:0042325	regulation of phosphorylation	1.003657e-3
GO:0010717	regulation of epithelial to mesenchymal transition	1.005721e-3
GO:0002768	immune response-regulating cell surface receptor signaling pathway	1.078004e-3
GO:0015747	urate transport	1.078090e-3
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	1.078090e-3
GO:0071840	cellular component organization or biogenesis	1.091166e-3
GO:0007623	circadian rhythm	1.095964e-3
GO:0048387	negative regulation of retinoic acid receptor signaling pathway	1.105628e-3
GO:0006955	immune response	1.114763e-3
GO:0009566	fertilization	1.131193e-3
GO:0009451	RNA modification	1.132807e-3
GO:0031669	cellular response to nutrient levels	1.146191e-3
GO:0034721	histone H3-K4 demethylation, trimethyl-H3-K4-specific	1.161077e-3
GO:0070508	cholesterol import	1.163075e-3
GO:0043249	erythrocyte maturation	1.163075e-3
GO:0002720	positive regulation of cytokine production involved in immune response	1.166805e-3
GO:0045666	positive regulation of neuron differentiation	1.168613e-3
GO:0019230	proprioception	1.171474e-3
GO:0021879	forebrain neuron differentiation	1.200562e-3
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	1.207585e-3
GO:0033138	positive regulation of peptidyl-serine phosphorylation	1.219765e-3
GO:0033631	cell-cell adhesion mediated by integrin	1.235410e-3
GO:0022412	cellular process involved in reproduction in multicellular organism	1.242935e-3
GO:0045216	cell-cell junction organization	1.248386e-3
GO:0010608	posttranscriptional regulation of gene expression	1.251878e-3
GO:0002429	immune response-activating cell surface receptor signaling pathway	1.260811e-3
GO:0010648	negative regulation of cell communication	1.264639e-3
GO:0034097	response to cytokine stimulus	1.302371e-3
GO:0019371	cyclooxygenase pathway	1.328650e-3
GO:2000224	regulation of testosterone biosynthetic process	1.332144e-3
GO:0048730	epidermis morphogenesis	1.352404e-3
GO:0051172	negative regulation of nitrogen compound metabolic process	1.360309e-3
GO:0048812	neuron projection morphogenesis	1.372805e-3
GO:0032488	Cdc42 protein signal transduction	1.380920e-3
GO:0046129	purine ribonucleoside biosynthetic process	1.387867e-3
GO:0008283	cell proliferation	1.405508e-3
GO:0051093	negative regulation of developmental process	1.414685e-3
GO:0006400	tRNA modification	1.437472e-3
GO:0042476	odontogenesis	1.443172e-3
GO:0000003	reproduction	1.452752e-3
GO:0071842	cellular component organization at cellular level	1.454496e-3
GO:0006396	RNA processing	1.468694e-3
GO:0044419	interspecies interaction between organisms	1.473802e-3
GO:0001914	regulation of T cell mediated cytotoxicity	1.486079e-3
GO:0032386	regulation of intracellular transport	1.495180e-3
GO:0032103	positive regulation of response to external stimulus	1.498226e-3
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	1.502393e-3
GO:0007338	single fertilization	1.531815e-3
GO:0051340	regulation of ligase activity	1.532136e-3
GO:0042493	response to drug	1.547649e-3
GO:0060429	epithelium development	1.550349e-3
GO:0009179	purine ribonucleoside diphosphate metabolic process	1.590150e-3
GO:0051968	positive regulation of synaptic transmission, glutamatergic	1.625549e-3
GO:0046649	lymphocyte activation	1.628009e-3
GO:0021870	Cajal-Retzius cell differentiation	1.632178e-3
GO:0016050	vesicle organization	1.639997e-3
GO:0001934	positive regulation of protein phosphorylation	1.687851e-3
GO:0042742	defense response to bacterium	1.714684e-3
GO:0002791	regulation of peptide secretion	1.719720e-3
GO:0051438	regulation of ubiquitin-protein ligase activity	1.729096e-3
GO:0065003	macromolecular complex assembly	1.729941e-3
GO:0010810	regulation of cell-substrate adhesion	1.747547e-3
GO:0042255	ribosome assembly	1.755618e-3
GO:0031652	positive regulation of heat generation	1.755618e-3
GO:0051966	regulation of synaptic transmission, glutamatergic	1.772835e-3
GO:0009409	response to cold	1.777130e-3
GO:0014074	response to purine-containing compound	1.780231e-3
GO:0007521	muscle cell fate determination	1.787186e-3
GO:0045937	positive regulation of phosphate metabolic process	1.798507e-3
GO:0046092	deoxycytidine metabolic process	1.834267e-3
GO:0006420	arginyl-tRNA aminoacylation	1.834267e-3
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	1.851829e-3
GO:0051051	negative regulation of transport	1.859193e-3
GO:0045637	regulation of myeloid cell differentiation	1.859799e-3
GO:0050884	neuromuscular process controlling posture	1.860022e-3
GO:0017085	response to insecticide	1.864327e-3
GO:0002274	myeloid leukocyte activation	1.867250e-3
GO:0001958	endochondral ossification	1.871644e-3
GO:0034377	plasma lipoprotein particle assembly	1.900537e-3
GO:0007420	brain development	1.936074e-3
GO:0016043	cellular component organization	1.941319e-3
GO:0045596	negative regulation of cell differentiation	1.962846e-3
GO:0048610	cellular process involved in reproduction	1.979020e-3
GO:0035556	intracellular signal transduction	1.991640e-3
GO:0051702	interaction with symbiont	2.000063e-3
GO:0045652	regulation of megakaryocyte differentiation	2.004077e-3
GO:0010469	regulation of receptor activity	2.006760e-3
GO:0070201	regulation of establishment of protein localization	2.012462e-3
GO:0007164	establishment of tissue polarity	2.029424e-3
GO:0007585	respiratory gaseous exchange	2.088432e-3
GO:0051654	establishment of mitochondrion localization	2.089122e-3
GO:0060285	ciliary cell motility	2.099823e-3
GO:0061077	chaperone-mediated protein folding	2.126614e-3
GO:0042753	positive regulation of circadian rhythm	2.130961e-3
GO:0007264	small GTPase mediated signal transduction	2.153849e-3
GO:0044237	cellular metabolic process	2.209979e-3
GO:0006352	transcription initiation, DNA-dependent	2.224695e-3
GO:0007283	spermatogenesis	2.247443e-3
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	2.262907e-3
GO:0045603	positive regulation of endothelial cell differentiation	2.270986e-3
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	2.314065e-3
GO:0050793	regulation of developmental process	2.320363e-3
GO:0006426	glycyl-tRNA aminoacylation	2.335187e-3
GO:0030099	myeloid cell differentiation	2.356203e-3
GO:0055080	cation homeostasis	2.369629e-3
GO:0048468	cell development	2.375031e-3
GO:0045039	protein import into mitochondrial inner membrane	2.383276e-3
GO:0034375	high-density lipoprotein particle remodeling	2.447746e-3
GO:0007596	blood coagulation	2.450641e-3
GO:0050920	regulation of chemotaxis	2.451067e-3
GO:0050707	regulation of cytokine secretion	2.459291e-3
GO:0014916	regulation of lung blood pressure	2.465780e-3
GO:0010629	negative regulation of gene expression	2.470855e-3
GO:0071496	cellular response to external stimulus	2.490583e-3
GO:0072668	tubulin complex biogenesis	2.534272e-3
GO:0002689	negative regulation of leukocyte chemotaxis	2.535763e-3
GO:0050684	regulation of mRNA processing	2.535883e-3
GO:0045416	positive regulation of interleukin-8 biosynthetic process	2.537312e-3
GO:0042475	odontogenesis of dentine-containing tooth	2.567280e-3
GO:0048302	regulation of isotype switching to IgG isotypes	2.568011e-3
GO:0051052	regulation of DNA metabolic process	2.572280e-3
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	2.576182e-3
GO:0003006	developmental process involved in reproduction	2.589012e-3
GO:0007167	enzyme linked receptor protein signaling pathway	2.590142e-3
GO:0042036	negative regulation of cytokine biosynthetic process	2.603849e-3
GO:0009266	response to temperature stimulus	2.631049e-3
GO:0006875	cellular metal ion homeostasis	2.645424e-3
GO:0017038	protein import	2.645942e-3
GO:0001812	positive regulation of type I hypersensitivity	2.645976e-3
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	2.671166e-3
GO:0046415	urate metabolic process	2.706704e-3
GO:0045087	innate immune response	2.734114e-3
GO:0019751	polyol metabolic process	2.737549e-3
GO:0006397	mRNA processing	2.760564e-3
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	2.764757e-3
GO:0031102	neuron projection regeneration	2.767956e-3
GO:0010769	regulation of cell morphogenesis involved in differentiation	2.789369e-3
GO:0003158	endothelium development	2.847589e-3