Novel motif:146

name:	motif146_AGACGAAGA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0040040	thermosensory behavior	7.769053e-10
GO:0071460	cellular response to cell-matrix adhesion	1.933177e-9
GO:0033693	neurofilament bundle assembly	3.606949e-9
GO:0045104	intermediate filament cytoskeleton organization	1.175122e-8
GO:0061048	negative regulation of branching involved in lung morphogenesis	1.743392e-8
GO:2000098	negative regulation of smooth muscle cell-matrix adhesion	3.703342e-8
GO:0071258	cellular response to gravity	3.703342e-8
GO:0061044	negative regulation of vascular wound healing	3.703342e-8
GO:0035491	positive regulation of leukotriene production involved in inflammatory response	3.703342e-8
GO:0034116	positive regulation of heterotypic cell-cell adhesion	6.525563e-8
GO:0051549	positive regulation of keratinocyte migration	6.753030e-8
GO:0008090	retrograde axon cargo transport	8.699165e-8
GO:2000369	regulation of clathrin-mediated endocytosis	8.706219e-8
GO:0045103	intermediate filament-based process	1.237784e-7
GO:0002439	chronic inflammatory response to antigenic stimulus	1.488208e-7
GO:0033629	negative regulation of cell adhesion mediated by integrin	1.583004e-7
GO:0032800	receptor biosynthetic process	1.652340e-7
GO:0015827	tryptophan transport	2.203822e-7
GO:0030730	sequestering of triglyceride	2.849409e-7
GO:0008211	glucocorticoid metabolic process	2.982716e-7
GO:0050829	defense response to Gram-negative bacterium	3.372630e-7
GO:0006412	translation	3.632783e-7
GO:0045109	intermediate filament organization	3.931510e-7
GO:0010467	gene expression	6.560010e-7
GO:0008089	anterograde axon cargo transport	6.984152e-7
GO:2000097	regulation of smooth muscle cell-matrix adhesion	7.647550e-7
GO:2000370	positive regulation of clathrin-mediated endocytosis	9.469613e-7
GO:0000726	non-recombinational repair	9.604712e-7
GO:0042574	retinal metabolic process	1.065141e-6
GO:0044140	negative regulation of growth of symbiont on or near host surface	1.253987e-6
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	1.513563e-6
GO:0060075	regulation of resting membrane potential	1.748624e-6
GO:0010608	posttranscriptional regulation of gene expression	2.227217e-6
GO:0051533	positive regulation of NFAT protein import into nucleus	2.610855e-6
GO:0006303	double-strand break repair via nonhomologous end joining	2.816301e-6
GO:0060052	neurofilament cytoskeleton organization	3.306439e-6
GO:0019087	transformation of host cell by virus	3.315655e-6
GO:0006726	eye pigment biosynthetic process	3.340087e-6
GO:0000712	resolution of meiotic recombination intermediates	3.378504e-6
GO:0045110	intermediate filament bundle assembly	3.794775e-6
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	3.920874e-6
GO:0034114	regulation of heterotypic cell-cell adhesion	3.920874e-6
GO:0015801	aromatic amino acid transport	4.414763e-6
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	4.586307e-6
GO:0032642	regulation of chemokine production	4.700936e-6
GO:0010624	regulation of Schwann cell proliferation	5.452266e-6
GO:0042035	regulation of cytokine biosynthetic process	5.564316e-6
GO:0043243	positive regulation of protein complex disassembly	7.008140e-6
GO:0032757	positive regulation of interleukin-8 production	7.735591e-6
GO:0016032	viral reproduction	7.923745e-6
GO:0002437	inflammatory response to antigenic stimulus	8.352058e-6
GO:0071803	positive regulation of podosome assembly	8.435328e-6
GO:0006417	regulation of translation	9.259124e-6
GO:0071316	cellular response to nicotine	9.639813e-6
GO:0071219	cellular response to molecule of bacterial origin	9.690204e-6
GO:0060988	lipid tube assembly	1.111296e-5
GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	1.174645e-5
GO:0060558	regulation of calcidiol 1-monooxygenase activity	1.177170e-5
GO:0019896	axon transport of mitochondrion	1.185560e-5
GO:0043616	keratinocyte proliferation	1.411612e-5
GO:0045672	positive regulation of osteoclast differentiation	1.592142e-5
GO:0060603	mammary gland duct morphogenesis	1.778929e-5
GO:0032793	positive regulation of CREB transcription factor activity	1.823047e-5
GO:0016226	iron-sulfur cluster assembly	1.882437e-5
GO:0045408	regulation of interleukin-6 biosynthetic process	1.948749e-5
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	2.004369e-5
GO:0018283	iron incorporation into metallo-sulfur cluster	2.116123e-5
GO:0071216	cellular response to biotic stimulus	2.358572e-5
GO:0060745	mammary gland branching involved in pregnancy	2.518046e-5
GO:0070340	detection of bacterial lipopeptide	2.663934e-5
GO:0044003	modification by symbiont of host morphology or physiology	2.734239e-5
GO:0015919	peroxisomal membrane transport	2.914600e-5
GO:0060751	branch elongation involved in mammary gland duct branching	3.031663e-5
GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation	3.126644e-5
GO:0019047	provirus integration	3.297403e-5
GO:0048193	Golgi vesicle transport	3.508917e-5
GO:0032677	regulation of interleukin-8 production	3.638184e-5
GO:0006398	histone mRNA 3'-end processing	3.679155e-5
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	3.703593e-5
GO:0006369	termination of RNA polymerase II transcription	4.066055e-5
GO:0009948	anterior/posterior axis specification	4.147686e-5
GO:0090304	nucleic acid metabolic process	4.224369e-5
GO:0008088	axon cargo transport	4.236360e-5
GO:0045073	regulation of chemokine biosynthetic process	4.983804e-5
GO:0046732	active induction of host immune response by virus	5.094581e-5
GO:0071222	cellular response to lipopolysaccharide	5.110613e-5
GO:0060557	positive regulation of vitamin D biosynthetic process	5.113269e-5
GO:0045084	positive regulation of interleukin-12 biosynthetic process	5.522498e-5
GO:0051208	sequestering of calcium ion	5.627959e-5
GO:0007021	tubulin complex assembly	5.737156e-5
GO:0009880	embryonic pattern specification	6.054809e-5
GO:0050901	leukocyte tethering or rolling	6.117446e-5
GO:0030225	macrophage differentiation	6.178174e-5
GO:0042534	regulation of tumor necrosis factor biosynthetic process	6.219901e-5
GO:0071283	cellular response to iron(III) ion	6.619250e-5
GO:0060623	regulation of chromosome condensation	6.619250e-5
GO:0046680	response to DDT	6.619250e-5
GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	6.619250e-5
GO:0045994	positive regulation of translational initiation by iron	6.793056e-5
GO:0002037	negative regulation of L-glutamate transport	6.793056e-5
GO:0032490	detection of molecule of bacterial origin	6.869518e-5
GO:0032722	positive regulation of chemokine production	7.168045e-5
GO:0010625	positive regulation of Schwann cell proliferation	7.321461e-5
GO:0052509	positive regulation by symbiont of host defense response	7.916983e-5
GO:0006438	valyl-tRNA aminoacylation	8.062105e-5
GO:0070265	necrotic cell death	8.523537e-5
GO:0046687	response to chromate	8.848302e-5
GO:0033986	response to methanol	8.848302e-5
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	8.852508e-5
GO:0071404	cellular response to low-density lipoprotein particle stimulus	1.006392e-4
GO:0001659	temperature homeostasis	1.028524e-4
GO:0033617	mitochondrial respiratory chain complex IV assembly	1.163081e-4
GO:0060444	branching involved in mammary gland duct morphogenesis	1.174666e-4
GO:0060556	regulation of vitamin D biosynthetic process	1.179601e-4
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	1.229352e-4
GO:0006418	tRNA aminoacylation for protein translation	1.237877e-4
GO:0015824	proline transport	1.302006e-4
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	1.320993e-4
GO:0009059	macromolecule biosynthetic process	1.329079e-4
GO:0050729	positive regulation of inflammatory response	1.344381e-4
GO:0045410	positive regulation of interleukin-6 biosynthetic process	1.347106e-4
GO:0002765	immune response-inhibiting signal transduction	1.381421e-4
GO:0009755	hormone-mediated signaling pathway	1.415325e-4
GO:0016070	RNA metabolic process	1.436441e-4
GO:0009636	response to toxin	1.479896e-4
GO:0050715	positive regulation of cytokine secretion	1.517614e-4
GO:0071727	cellular response to triacyl bacterial lipopeptide	1.525457e-4
GO:0042495	detection of triacyl bacterial lipopeptide	1.525457e-4
GO:0006447	regulation of translational initiation by iron	1.537955e-4
GO:0050714	positive regulation of protein secretion	1.666901e-4
GO:0051650	establishment of vesicle localization	1.724133e-4
GO:0002573	myeloid leukocyte differentiation	1.747001e-4
GO:2000617	positive regulation of histone H3-K9 acetylation	1.816012e-4
GO:2000620	positive regulation of histone H4-K16 acetylation	1.816012e-4
GO:0070625	zymogen granule exocytosis	1.816012e-4
GO:0070512	positive regulation of histone H4-K20 methylation	1.816012e-4
GO:0000185	activation of MAPKKK activity	1.906960e-4
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.967537e-4
GO:0016046	detection of fungus	1.967537e-4
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.967537e-4
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	2.067672e-4
GO:0019048	virus-host interaction	2.105442e-4
GO:0060322	head development	2.377758e-4
GO:0034645	cellular macromolecule biosynthetic process	2.408644e-4
GO:0051099	positive regulation of binding	2.412880e-4
GO:0031622	positive regulation of fever generation	2.478999e-4
GO:0031124	mRNA 3'-end processing	2.508129e-4
GO:0031293	membrane protein intracellular domain proteolysis	2.518594e-4
GO:0045670	regulation of osteoclast differentiation	2.551767e-4
GO:0071637	regulation of monocyte chemotactic protein-1 production	2.700568e-4
GO:0072668	tubulin complex biogenesis	2.743004e-4
GO:0071402	cellular response to lipoprotein particle stimulus	2.743004e-4
GO:0022415	viral reproductive process	2.810957e-4
GO:0003012	muscle system process	2.957292e-4
GO:0014805	smooth muscle adaptation	3.113602e-4
GO:0043279	response to alkaloid	3.266577e-4
GO:0045948	positive regulation of translational initiation	3.324483e-4
GO:0000226	microtubule cytoskeleton organization	3.501867e-4
GO:0043500	muscle adaptation	3.531656e-4
GO:0009107	lipoate biosynthetic process	3.548119e-4
GO:0034754	cellular hormone metabolic process	3.602310e-4
GO:0046730	induction of host immune response by virus	3.643048e-4
GO:0042487	regulation of odontogenesis of dentine-containing tooth	3.643048e-4
GO:0032675	regulation of interleukin-6 production	3.661227e-4
GO:0035767	endothelial cell chemotaxis	3.687860e-4
GO:0090232	positive regulation of spindle checkpoint	3.789007e-4
GO:0042987	amyloid precursor protein catabolic process	3.892499e-4
GO:0043148	mitotic spindle stabilization	3.928663e-4
GO:0002036	regulation of L-glutamate transport	4.119248e-4
GO:0050908	detection of light stimulus involved in visual perception	4.186192e-4
GO:2000615	regulation of histone H3-K9 acetylation	4.264048e-4
GO:0003009	skeletal muscle contraction	4.291960e-4
GO:0010829	negative regulation of glucose transport	4.314681e-4
GO:0006422	aspartyl-tRNA aminoacylation	4.433024e-4
GO:0090196	regulation of chemokine secretion	4.666384e-4
GO:0015804	neutral amino acid transport	4.739573e-4
GO:0002237	response to molecule of bacterial origin	4.760340e-4
GO:0014912	negative regulation of smooth muscle cell migration	4.774823e-4
GO:0050885	neuromuscular process controlling balance	4.805364e-4
GO:0001300	chronological cell aging	4.805561e-4
GO:0006903	vesicle targeting	4.862097e-4
GO:0001817	regulation of cytokine production	4.958711e-4
GO:0002739	regulation of cytokine secretion involved in immune response	4.965569e-4
GO:0032926	negative regulation of activin receptor signaling pathway	4.970886e-4
GO:0030574	collagen catabolic process	5.232828e-4
GO:0051956	negative regulation of amino acid transport	5.234730e-4
GO:0060251	regulation of glial cell proliferation	5.314618e-4
GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway	5.332322e-4
GO:0072285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	5.332322e-4
GO:0060248	detection of cell density by contact stimulus involved in contact inhibition	5.332322e-4
GO:0007371	ventral midline determination	5.332322e-4
GO:0015696	ammonium transport	5.353453e-4
GO:0015680	intracellular copper ion transport	5.376058e-4
GO:0014038	regulation of Schwann cell differentiation	5.482369e-4
GO:0000375	RNA splicing, via transesterification reactions	5.549745e-4
GO:0031652	positive regulation of heat generation	5.573797e-4
GO:0032680	regulation of tumor necrosis factor production	5.581715e-4
GO:0034014	response to triglyceride	5.589153e-4
GO:0042108	positive regulation of cytokine biosynthetic process	5.632699e-4
GO:0050905	neuromuscular process	5.699296e-4
GO:0061043	regulation of vascular wound healing	5.804452e-4
GO:0032496	response to lipopolysaccharide	5.888326e-4
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	6.005765e-4
GO:0000398	nuclear mRNA splicing, via spliceosome	6.099732e-4
GO:0033590	response to cobalamin	6.141916e-4
GO:0006117	acetaldehyde metabolic process	6.141916e-4
GO:0019227	neuronal action potential propagation	6.235204e-4
GO:0035553	oxidative single-stranded RNA demethylation	6.358323e-4
GO:0031644	regulation of neurological system process	6.642324e-4
GO:0051984	positive regulation of chromosome segregation	6.643746e-4
GO:0001660	fever generation	6.675000e-4
GO:0051457	maintenance of protein location in nucleus	6.942713e-4
GO:0060020	Bergmann glial cell differentiation	7.016887e-4
GO:0032729	positive regulation of interferon-gamma production	7.064133e-4
GO:0051235	maintenance of location	7.282561e-4
GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	7.374946e-4
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	7.672195e-4
GO:0045080	positive regulation of chemokine biosynthetic process	7.748380e-4
GO:0010817	regulation of hormone levels	7.856235e-4
GO:0051257	spindle midzone assembly involved in meiosis	7.896296e-4
GO:0007060	male meiosis chromosome segregation	7.896296e-4
GO:0030302	deoxynucleotide transport	7.896296e-4
GO:0042536	negative regulation of tumor necrosis factor biosynthetic process	7.949440e-4
GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	7.989453e-4
GO:0010034	response to acetate	8.228021e-4
GO:2000193	positive regulation of fatty acid transport	8.292257e-4
GO:0019915	lipid storage	8.475988e-4
GO:0032755	positive regulation of interleukin-6 production	8.516398e-4
GO:0072595	maintenance of protein localization to organelle	8.583121e-4
GO:0006352	transcription initiation, DNA-dependent	8.712197e-4
GO:0070988	demethylation	9.320339e-4
GO:0045870	positive regulation of retroviral genome replication	1.061184e-3
GO:0003094	glomerular filtration	1.061184e-3
GO:0002537	nitric oxide production involved in inflammatory response	1.086235e-3
GO:0048385	regulation of retinoic acid receptor signaling pathway	1.091686e-3
GO:0033687	osteoblast proliferation	1.108619e-3
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	1.120051e-3
GO:0050707	regulation of cytokine secretion	1.126428e-3
GO:0019059	initiation of viral infection	1.135433e-3
GO:0042482	positive regulation of odontogenesis	1.147784e-3
GO:0055093	response to hyperoxia	1.158884e-3
GO:0014040	positive regulation of Schwann cell differentiation	1.161863e-3
GO:0051701	interaction with host	1.167449e-3
GO:0006936	muscle contraction	1.168152e-3
GO:0021612	facial nerve structural organization	1.180322e-3
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	1.183933e-3
GO:0042036	negative regulation of cytokine biosynthetic process	1.192969e-3
GO:0019233	sensory perception of pain	1.197904e-3
GO:0009408	response to heat	1.203252e-3
GO:0021532	neural tube patterning	1.232519e-3
GO:0090197	positive regulation of chemokine secretion	1.263672e-3
GO:0050727	regulation of inflammatory response	1.270416e-3
GO:0060252	positive regulation of glial cell proliferation	1.298657e-3
GO:0060324	face development	1.351474e-3
GO:0035584	calcium-mediated signaling using intracellular calcium source	1.409358e-3
GO:0014048	regulation of glutamate secretion	1.441301e-3
GO:0070164	negative regulation of adiponectin secretion	1.448008e-3
GO:0060355	positive regulation of cell adhesion molecule production	1.448008e-3
GO:0035505	positive regulation of myosin light chain kinase activity	1.448008e-3
GO:0032308	positive regulation of prostaglandin secretion	1.464803e-3
GO:0042445	hormone metabolic process	1.464869e-3
GO:0031081	nuclear pore distribution	1.467312e-3
GO:0019058	viral infectious cycle	1.518833e-3
GO:0042508	tyrosine phosphorylation of Stat1 protein	1.522648e-3
GO:0045124	regulation of bone resorption	1.526095e-3
GO:0015808	L-alanine transport	1.538163e-3
GO:0033127	regulation of histone phosphorylation	1.544647e-3
GO:0051293	establishment of spindle localization	1.583671e-3
GO:0031123	RNA 3'-end processing	1.585337e-3
GO:0007389	pattern specification process	1.592118e-3
GO:0060555	induction of necroptosis by extracellular signals	1.606201e-3
GO:0071726	cellular response to diacyl bacterial lipopeptide	1.606201e-3
GO:0042496	detection of diacyl bacterial lipopeptide	1.606201e-3
GO:0060011	Sertoli cell proliferation	1.616104e-3
GO:0042982	amyloid precursor protein metabolic process	1.623819e-3
GO:0043039	tRNA aminoacylation	1.650059e-3
GO:0002315	marginal zone B cell differentiation	1.692964e-3
GO:0045064	T-helper 2 cell differentiation	1.692964e-3
GO:0043244	regulation of protein complex disassembly	1.693423e-3
GO:0051969	regulation of transmission of nerve impulse	1.717327e-3
GO:0007026	negative regulation of microtubule depolymerization	1.726326e-3
GO:0055098	response to low-density lipoprotein particle stimulus	1.729055e-3
GO:0048199	vesicle targeting, to, from or within Golgi	1.746866e-3
GO:0006397	mRNA processing	1.768940e-3
GO:0051656	establishment of organelle localization	1.817937e-3
GO:0033299	secretion of lysosomal enzymes	1.819448e-3
GO:0043388	positive regulation of DNA binding	1.826351e-3
GO:0032892	positive regulation of organic acid transport	1.832013e-3
GO:0043473	pigmentation	1.839681e-3
GO:0010469	regulation of receptor activity	1.840866e-3
GO:0043113	receptor clustering	1.877484e-3
GO:0032102	negative regulation of response to external stimulus	1.893715e-3
GO:0001523	retinoid metabolic process	1.903334e-3
GO:0042346	positive regulation of NF-kappaB import into nucleus	1.956119e-3
GO:0045556	positive regulation of TRAIL biosynthetic process	1.993707e-3
GO:0001768	establishment of T cell polarity	2.003028e-3
GO:0060356	leucine import	2.020675e-3
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	2.020675e-3
GO:0035552	oxidative single-stranded DNA demethylation	2.020675e-3
GO:0006399	tRNA metabolic process	2.021538e-3
GO:0021561	facial nerve development	2.024956e-3
GO:0052200	response to host defenses	2.031708e-3
GO:0055094	response to lipoprotein stimulus	2.062310e-3
GO:0022411	cellular component disassembly	2.082879e-3
GO:0048167	regulation of synaptic plasticity	2.094454e-3
GO:0042993	positive regulation of transcription factor import into nucleus	2.110535e-3
GO:0042245	RNA repair	2.115339e-3
GO:0030518	steroid hormone receptor signaling pathway	2.126965e-3
GO:0046850	regulation of bone remodeling	2.174581e-3
GO:0048205	COPI coating of Golgi vesicle	2.197559e-3
GO:0061198	fungiform papilla formation	2.202491e-3
GO:0006886	intracellular protein transport	2.267163e-3
GO:0048545	response to steroid hormone stimulus	2.272344e-3
GO:0000060	protein import into nucleus, translocation	2.340354e-3
GO:0002230	positive regulation of defense response to virus by host	2.397365e-3
GO:0010193	response to ozone	2.402089e-3
GO:0006776	vitamin A metabolic process	2.422015e-3
GO:0060005	vestibular reflex	2.437601e-3
GO:0070163	regulation of adiponectin secretion	2.466494e-3
GO:0021836	chemorepulsion involved in postnatal olfactory bulb interneuron migration	2.472177e-3
GO:0001503	ossification	2.489912e-3
GO:0048752	semicircular canal morphogenesis	2.492876e-3
GO:0002740	negative regulation of cytokine secretion involved in immune response	2.507552e-3
GO:0008207	C21-steroid hormone metabolic process	2.549301e-3
GO:0007098	centrosome cycle	2.550239e-3
GO:0042481	regulation of odontogenesis	2.592808e-3
GO:0042921	glucocorticoid receptor signaling pathway	2.630126e-3
GO:0046883	regulation of hormone secretion	2.684626e-3
GO:0008380	RNA splicing	2.738097e-3
GO:0033198	response to ATP	2.758660e-3
GO:0051303	establishment of chromosome localization	2.797437e-3
GO:0032525	somite rostral/caudal axis specification	2.802493e-3
GO:0051222	positive regulation of protein transport	2.830465e-3
GO:0051580	regulation of neurotransmitter uptake	2.831402e-3
GO:0021870	Cajal-Retzius cell differentiation	2.873146e-3
GO:0030241	skeletal muscle myosin thick filament assembly	2.919896e-3
GO:0045429	positive regulation of nitric oxide biosynthetic process	2.938896e-3
GO:0019730	antimicrobial humoral response	2.969343e-3
GO:0031114	regulation of microtubule depolymerization	2.990684e-3
GO:0021592	fourth ventricle development	2.995626e-3
GO:0010107	potassium ion import	3.039293e-3
GO:0010470	regulation of gastrulation	3.067549e-3
GO:0032663	regulation of interleukin-2 production	3.076793e-3
GO:0016101	diterpenoid metabolic process	3.107067e-3
GO:0001662	behavioral fear response	3.112364e-3
GO:0002718	regulation of cytokine production involved in immune response	3.127913e-3
GO:0032223	negative regulation of synaptic transmission, cholinergic	3.141485e-3
GO:0045212	neurotransmitter receptor biosynthetic process	3.141485e-3
GO:0006781	succinyl-CoA pathway	3.141485e-3
GO:0071223	cellular response to lipoteichoic acid	3.167759e-3
GO:0031110	regulation of microtubule polymerization or depolymerization	3.179796e-3
GO:0017148	negative regulation of translation	3.212899e-3
GO:0019439	aromatic compound catabolic process	3.223319e-3
GO:0042596	fear response	3.290960e-3
GO:0000183	chromatin silencing at rDNA	3.297501e-3
GO:0007220	Notch receptor processing	3.355180e-3
GO:0032707	negative regulation of interleukin-23 production	3.360084e-3
GO:0002051	osteoblast fate commitment	3.360084e-3
GO:0021546	rhombomere development	3.394365e-3
GO:0071221	cellular response to bacterial lipopeptide	3.394365e-3
GO:0051563	smooth endoplasmic reticulum calcium ion homeostasis	3.396838e-3
GO:0046627	negative regulation of insulin receptor signaling pathway	3.399123e-3
GO:0042345	regulation of NF-kappaB import into nucleus	3.422617e-3
GO:0061180	mammary gland epithelium development	3.422625e-3
GO:0009266	response to temperature stimulus	3.444645e-3
GO:0033129	positive regulation of histone phosphorylation	3.451963e-3
GO:0048386	positive regulation of retinoic acid receptor signaling pathway	3.460009e-3
GO:0042404	thyroid hormone catabolic process	3.555717e-3
GO:0032355	response to estradiol stimulus	3.562754e-3
GO:0014050	negative regulation of glutamate secretion	3.605815e-3
GO:0003401	axis elongation	3.619348e-3
GO:0035039	male pronucleus assembly	3.701782e-3
GO:0061196	fungiform papilla development	3.750164e-3
GO:0006413	translational initiation	3.799961e-3
GO:0035094	response to nicotine	3.804619e-3
GO:0071312	cellular response to alkaloid	3.818457e-3
GO:0090022	regulation of neutrophil chemotaxis	3.931250e-3
GO:0060443	mammary gland morphogenesis	3.963570e-3
GO:0035921	desmosome disassembly	3.991064e-3
GO:0070563	negative regulation of vitamin D receptor signaling pathway	3.991064e-3
GO:0000086	G2/M transition of mitotic cell cycle	4.036578e-3
GO:0009235	cobalamin metabolic process	4.052516e-3
GO:0018230	peptidyl-L-cysteine S-palmitoylation	4.131281e-3
GO:0002209	behavioral defense response	4.170127e-3
GO:0006353	transcription termination, DNA-dependent	4.187723e-3
GO:0050796	regulation of insulin secretion	4.222505e-3
GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	4.249851e-3
GO:0016584	nucleosome positioning	4.252968e-3
GO:0043932	ossification involved in bone remodeling	4.252968e-3
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	4.268311e-3
GO:0045085	negative regulation of interleukin-2 biosynthetic process	4.283887e-3
GO:0034205	beta-amyloid formation	4.283887e-3
GO:0061046	regulation of branching involved in lung morphogenesis	4.341770e-3
GO:0032103	positive regulation of response to external stimulus	4.346908e-3
GO:0031111	negative regulation of microtubule polymerization or depolymerization	4.348095e-3
GO:0006396	RNA processing	4.358222e-3
GO:0045075	regulation of interleukin-12 biosynthetic process	4.384144e-3
GO:0032733	positive regulation of interleukin-10 production	4.392741e-3
GO:0032495	response to muramyl dipeptide	4.412436e-3
GO:0050995	negative regulation of lipid catabolic process	4.415192e-3
GO:0021678	third ventricle development	4.485317e-3
GO:0097039	protein linear polyubiquitination	4.485317e-3
GO:0006379	mRNA cleavage	4.566841e-3
GO:0016049	cell growth	4.628343e-3
GO:0043402	glucocorticoid mediated signaling pathway	4.661746e-3
GO:0048194	Golgi vesicle budding	4.721195e-3
GO:0003002	regionalization	4.736550e-3
GO:0006357	regulation of transcription from RNA polymerase II promoter	4.759557e-3
GO:0016081	synaptic vesicle docking involved in exocytosis	4.823588e-3
GO:0043534	blood vessel endothelial cell migration	4.876886e-3
GO:0006414	translational elongation	4.882536e-3
GO:0070350	regulation of white fat cell proliferation	4.884347e-3
GO:0043526	neuroprotection	4.894652e-3
GO:0031117	positive regulation of microtubule depolymerization	4.930024e-3
GO:0000076	DNA replication checkpoint	4.938353e-3
GO:0045785	positive regulation of cell adhesion	5.034453e-3
GO:0009952	anterior/posterior pattern specification	5.080958e-3
GO:0007017	microtubule-based process	5.127105e-3
GO:0071822	protein complex subunit organization	5.143400e-3
GO:0033628	regulation of cell adhesion mediated by integrin	5.196291e-3
GO:0048871	multicellular organismal homeostasis	5.197183e-3
GO:0051043	regulation of membrane protein ectodomain proteolysis	5.245075e-3
GO:0032328	alanine transport	5.253608e-3
GO:0070507	regulation of microtubule cytoskeleton organization	5.282584e-3
GO:0006403	RNA localization	5.287984e-3
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	5.313032e-3
GO:0031064	negative regulation of histone deacetylation	5.331048e-3
GO:0051101	regulation of DNA binding	5.332670e-3
GO:0045415	negative regulation of interleukin-8 biosynthetic process	5.355509e-3
GO:0033158	regulation of protein import into nucleus, translocation	5.355869e-3
GO:0043200	response to amino acid stimulus	5.359645e-3
GO:0071845	cellular component disassembly at cellular level	5.371515e-3
GO:0021570	rhombomere 4 development	5.388726e-3
GO:0060611	mammary gland fat development	5.450039e-3
GO:0071436	sodium ion export	5.461354e-3
GO:0043401	steroid hormone mediated signaling pathway	5.565988e-3
GO:0061011	hepatic duct development	5.631163e-3
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	5.638183e-3
GO:0009651	response to salt stress	5.703980e-3
GO:0002699	positive regulation of immune effector process	5.929445e-3
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	5.938494e-3
GO:0006892	post-Golgi vesicle-mediated transport	6.007517e-3
GO:0006590	thyroid hormone generation	6.048072e-3
GO:0016080	synaptic vesicle targeting	6.131457e-3
GO:0070374	positive regulation of ERK1 and ERK2 cascade	6.208417e-3
GO:0000132	establishment of mitotic spindle orientation	6.221321e-3
GO:0043060	meiotic metaphase I plate congression	6.224642e-3
GO:0090009	primitive streak formation	6.366435e-3
GO:0030917	midbrain-hindbrain boundary development	6.408342e-3
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	6.454468e-3
GO:0032967	positive regulation of collagen biosynthetic process	6.594482e-3
GO:0045630	positive regulation of T-helper 2 cell differentiation	6.621238e-3
GO:0051594	detection of glucose	6.691015e-3
GO:0014070	response to organic cyclic compound	6.699173e-3
GO:0051255	spindle midzone assembly	6.700592e-3
GO:0006446	regulation of translational initiation	6.706649e-3
GO:0015698	inorganic anion transport	6.721362e-3
GO:0030224	monocyte differentiation	6.726994e-3
GO:0010572	positive regulation of platelet activation	6.849260e-3
GO:2000348	regulation of CD40 signaling pathway	6.934737e-3
GO:0046827	positive regulation of protein export from nucleus	6.939462e-3
GO:0044060	regulation of endocrine process	6.953752e-3
GO:0032770	positive regulation of monooxygenase activity	7.008641e-3
GO:0043380	regulation of memory T cell differentiation	7.026452e-3
GO:0060602	branch elongation of an epithelium	7.041239e-3
GO:0021993	initiation of neural tube closure	7.098577e-3
GO:0032653	regulation of interleukin-10 production	7.185568e-3
GO:0042733	embryonic digit morphogenesis	7.289647e-3
GO:0046849	bone remodeling	7.351618e-3
GO:0051971	positive regulation of transmission of nerve impulse	7.368008e-3
GO:0045076	regulation of interleukin-2 biosynthetic process	7.428723e-3
GO:0042403	thyroid hormone metabolic process	7.444163e-3
GO:0051412	response to corticosterone stimulus	7.496585e-3
GO:0042219	cellular modified amino acid catabolic process	7.574584e-3
GO:0032474	otolith morphogenesis	7.591613e-3
GO:0050720	interleukin-1 beta biosynthetic process	7.591613e-3
GO:0042407	cristae formation	7.591613e-3
GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	7.591613e-3
GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	7.591613e-3
GO:2000330	positive regulation of T-helper 17 cell lineage commitment	7.621648e-3
GO:2000318	positive regulation of T-helper 17 type immune response	7.621648e-3
GO:0043585	nose morphogenesis	7.666939e-3
GO:0006927	transformed cell apoptosis	7.666939e-3
GO:0010468	regulation of gene expression	7.673572e-3
GO:0006359	regulation of transcription from RNA polymerase III promoter	7.800708e-3
GO:0006605	protein targeting	7.915016e-3
GO:0044403	symbiosis, encompassing mutualism through parasitism	7.924007e-3
GO:0006405	RNA export from nucleus	7.967142e-3
GO:0045663	positive regulation of myoblast differentiation	8.002235e-3
GO:0006987	activation of signaling protein activity involved in unfolded protein response	8.044633e-3
GO:0000578	embryonic axis specification	8.064498e-3
GO:0045885	positive regulation of survival gene product expression	8.087653e-3
GO:0040001	establishment of mitotic spindle localization	8.139363e-3
GO:0006979	response to oxidative stress	8.166877e-3
GO:0010225	response to UV-C	8.176216e-3
GO:0010626	negative regulation of Schwann cell proliferation	8.328023e-3
GO:0051643	endoplasmic reticulum localization	8.390361e-3
GO:0051588	regulation of neurotransmitter transport	8.462695e-3
GO:0043112	receptor metabolic process	8.464616e-3
GO:0009635	response to herbicide	8.491088e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0070646	protein modification by small protein removal	1.612368e-50
GO:0016579	protein deubiquitination	4.002496e-50
GO:0070647	protein modification by small protein conjugation or removal	1.123604e-14
GO:0032849	positive regulation of cellular pH reduction	4.404023e-10
GO:0006508	proteolysis	4.574692e-9
GO:0048026	positive regulation of nuclear mRNA splicing, via spliceosome	3.059442e-8
GO:0048247	lymphocyte chemotaxis	3.309936e-8
GO:0042119	neutrophil activation	3.382526e-8
GO:0046784	intronless viral mRNA export from host nucleus	1.398778e-7
GO:0002344	B cell affinity maturation	1.527822e-7
GO:0048240	sperm capacitation	1.539645e-7
GO:0015670	carbon dioxide transport	2.324900e-7
GO:0002827	positive regulation of T-helper 1 type immune response	2.450558e-7
GO:0002446	neutrophil mediated immunity	3.065837e-7
GO:0015669	gas transport	3.163730e-7
GO:0032847	regulation of cellular pH reduction	4.186879e-7
GO:0009134	nucleoside diphosphate catabolic process	5.345666e-7
GO:0008616	queuosine biosynthetic process	9.098222e-7
GO:0044260	cellular macromolecule metabolic process	1.029084e-6
GO:0016078	tRNA catabolic process	1.540253e-6
GO:0001682	tRNA 5'-leader removal	1.540253e-6
GO:2000345	regulation of hepatocyte proliferation	1.737983e-6
GO:0060012	synaptic transmission, glycinergic	2.302310e-6
GO:0051659	maintenance of mitochondrion location	2.418800e-6
GO:0009191	ribonucleoside diphosphate catabolic process	2.703597e-6
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	3.177413e-6
GO:0045104	intermediate filament cytoskeleton organization	3.814902e-6
GO:0034587	piRNA metabolic process	3.966944e-6
GO:0003350	pulmonary myocardium development	4.270089e-6
GO:0010986	positive regulation of lipoprotein particle clearance	4.890802e-6
GO:0008152	metabolic process	5.068305e-6
GO:0032074	negative regulation of nuclease activity	5.202427e-6
GO:0042026	protein refolding	5.458059e-6
GO:0002339	B cell selection	7.356706e-6
GO:0090086	negative regulation of protein deubiquitination	7.543508e-6
GO:0072573	tolerance induction to lipopolysaccharide	7.583143e-6
GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	7.583143e-6
GO:2000349	negative regulation of CD40 signaling pathway	7.583143e-6
GO:0070429	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	7.583143e-6
GO:0002632	negative regulation of granuloma formation	7.583143e-6
GO:0034148	negative regulation of toll-like receptor 5 signaling pathway	7.583143e-6
GO:0016559	peroxisome fission	8.638308e-6
GO:0045103	intermediate filament-based process	8.731744e-6
GO:0072676	lymphocyte migration	9.356139e-6
GO:0070389	chaperone cofactor-dependent protein refolding	9.967730e-6
GO:0055015	ventricular cardiac muscle cell development	1.114842e-5
GO:0045780	positive regulation of bone resorption	1.135771e-5
GO:0043170	macromolecule metabolic process	1.252414e-5
GO:0051321	meiotic cell cycle	1.302494e-5
GO:0009185	ribonucleoside diphosphate metabolic process	1.337087e-5
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	1.570099e-5
GO:0002443	leukocyte mediated immunity	1.601211e-5
GO:0051657	maintenance of organelle location	1.727716e-5
GO:2000347	positive regulation of hepatocyte proliferation	1.768219e-5
GO:0006290	pyrimidine dimer repair	1.779821e-5
GO:0046850	regulation of bone remodeling	1.786112e-5
GO:0033120	positive regulation of RNA splicing	1.826417e-5
GO:0045124	regulation of bone resorption	2.045587e-5
GO:0002444	myeloid leukocyte mediated immunity	2.417822e-5
GO:0060052	neurofilament cytoskeleton organization	2.444326e-5
GO:0061077	chaperone-mediated protein folding	2.485995e-5
GO:0031444	slow-twitch skeletal muscle fiber contraction	2.634636e-5
GO:0034105	positive regulation of tissue remodeling	2.703039e-5
GO:0048536	spleen development	2.920434e-5
GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	2.987399e-5
GO:0090076	relaxation of skeletal muscle	2.987399e-5
GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	2.987399e-5
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	2.987399e-5
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	2.987399e-5
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	3.034507e-5
GO:0034115	negative regulation of heterotypic cell-cell adhesion	3.210741e-5
GO:0031133	regulation of axon diameter	3.210741e-5
GO:0002315	marginal zone B cell differentiation	3.537850e-5
GO:0016578	histone deubiquitination	3.875880e-5
GO:0060600	dichotomous subdivision of an epithelial terminal unit	3.891032e-5
GO:0071824	protein-DNA complex subunit organization	4.179236e-5
GO:0051561	elevation of mitochondrial calcium ion concentration	4.741492e-5
GO:0051313	attachment of spindle microtubules to chromosome	4.903100e-5
GO:0044238	primary metabolic process	5.397178e-5
GO:0002829	negative regulation of type 2 immune response	5.613355e-5
GO:0002693	positive regulation of cellular extravasation	5.683638e-5
GO:0006334	nucleosome assembly	6.247634e-5
GO:0008617	guanosine metabolic process	6.416932e-5
GO:0060841	venous blood vessel development	7.046695e-5
GO:0002825	regulation of T-helper 1 type immune response	7.481208e-5
GO:2000348	regulation of CD40 signaling pathway	7.835154e-5
GO:0044237	cellular metabolic process	9.721146e-5
GO:0002407	dendritic cell chemotaxis	1.016474e-4
GO:0070509	calcium ion import	1.019011e-4
GO:2000507	positive regulation of energy homeostasis	1.025509e-4
GO:2000253	positive regulation of feeding behavior	1.025509e-4
GO:0042637	catagen	1.025509e-4
GO:0070536	protein K63-linked deubiquitination	1.038630e-4
GO:0032536	regulation of cell projection size	1.145459e-4
GO:0065004	protein-DNA complex assembly	1.186336e-4
GO:0030854	positive regulation of granulocyte differentiation	1.203635e-4
GO:0006457	protein folding	1.252065e-4
GO:0006970	response to osmotic stress	1.473874e-4
GO:0007126	meiosis	1.548380e-4
GO:0001906	cell killing	1.555595e-4
GO:0035752	lysosomal lumen pH elevation	1.574583e-4
GO:0001575	globoside metabolic process	1.574583e-4
GO:0000046	autophagic vacuole fusion	1.574583e-4
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	1.614954e-4
GO:0032846	positive regulation of homeostatic process	1.652163e-4
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	1.724061e-4
GO:0045109	intermediate filament organization	1.742102e-4
GO:0010507	negative regulation of autophagy	1.745510e-4
GO:2000344	positive regulation of acrosome reaction	1.774495e-4
GO:0034728	nucleosome organization	1.781804e-4
GO:0008608	attachment of spindle microtubules to kinetochore	1.825203e-4
GO:0002579	positive regulation of antigen processing and presentation	1.852929e-4
GO:0032663	regulation of interleukin-2 production	1.875642e-4
GO:0006259	DNA metabolic process	1.941576e-4
GO:0010631	epithelial cell migration	2.059853e-4
GO:0060592	mammary gland formation	2.235369e-4
GO:0001922	B-1 B cell homeostasis	2.248780e-4
GO:0071243	cellular response to arsenic-containing substance	2.299909e-4
GO:0031034	myosin filament assembly	2.427374e-4
GO:0010983	positive regulation of high-density lipoprotein particle clearance	2.496130e-4
GO:0048384	retinoic acid receptor signaling pathway	2.738587e-4
GO:0003012	muscle system process	2.755293e-4
GO:0002763	positive regulation of myeloid leukocyte differentiation	2.836987e-4
GO:0034139	regulation of toll-like receptor 3 signaling pathway	2.868526e-4
GO:0002761	regulation of myeloid leukocyte differentiation	2.913948e-4
GO:0000079	regulation of cyclin-dependent protein kinase activity	2.975757e-4
GO:0002274	myeloid leukocyte activation	3.004542e-4
GO:0071338	positive regulation of hair follicle cell proliferation	3.060432e-4
GO:0009132	nucleoside diphosphate metabolic process	3.207191e-4
GO:0043353	enucleate erythrocyte differentiation	3.218614e-4
GO:0030183	B cell differentiation	3.267794e-4
GO:0070537	histone H2A K63-linked deubiquitination	3.286873e-4
GO:0033299	secretion of lysosomal enzymes	3.286873e-4
GO:0051701	interaction with host	3.317776e-4
GO:0055005	ventricular cardiac myofibril development	4.101520e-4
GO:0009181	purine ribonucleoside diphosphate catabolic process	4.219726e-4
GO:0021516	dorsal spinal cord development	4.348108e-4
GO:0010724	regulation of definitive erythrocyte differentiation	4.355880e-4
GO:0030718	germ-line stem cell maintenance	4.453849e-4
GO:0034103	regulation of tissue remodeling	4.814459e-4
GO:0070561	vitamin D receptor signaling pathway	4.858024e-4
GO:0048284	organelle fusion	5.010445e-4
GO:0070098	chemokine-mediated signaling pathway	5.504242e-4
GO:0055003	cardiac myofibril assembly	5.635241e-4
GO:0040016	embryonic cleavage	5.680637e-4
GO:0048660	regulation of smooth muscle cell proliferation	5.723228e-4
GO:0032204	regulation of telomere maintenance	5.825344e-4
GO:0014819	regulation of skeletal muscle contraction	5.924925e-4
GO:0090085	regulation of protein deubiquitination	5.939331e-4
GO:0090084	negative regulation of inclusion body assembly	5.939331e-4
GO:0002335	mature B cell differentiation	6.023326e-4
GO:0006780	uroporphyrinogen III biosynthetic process	6.063724e-4
GO:0046079	dUMP catabolic process	6.097049e-4
GO:0043310	negative regulation of eosinophil degranulation	6.097049e-4
GO:2000409	positive regulation of T cell extravasation	6.097049e-4
GO:0070535	histone H2A K63-linked ubiquitination	6.097049e-4
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	6.097049e-4
GO:0035696	monocyte extravasation	6.097049e-4
GO:0035705	T-helper 17 cell chemotaxis	6.097049e-4
GO:0010900	negative regulation of phosphatidylcholine catabolic process	6.666009e-4
GO:0031032	actomyosin structure organization	6.770705e-4
GO:0007141	male meiosis I	6.855094e-4
GO:0045931	positive regulation of mitotic cell cycle	6.935951e-4
GO:0014048	regulation of glutamate secretion	7.288002e-4
GO:0061113	pancreas morphogenesis	7.394296e-4
GO:0009987	cellular process	7.407779e-4
GO:0002313	mature B cell differentiation involved in immune response	7.679534e-4
GO:0043201	response to leucine	7.783935e-4
GO:0060730	regulation of intestinal epithelial structure maintenance	7.835972e-4
GO:0035883	enteroendocrine cell differentiation	7.835972e-4
GO:0010984	regulation of lipoprotein particle clearance	7.840631e-4
GO:0060788	ectodermal placode formation	7.996900e-4
GO:0023035	CD40 signaling pathway	7.997383e-4
GO:0055013	cardiac muscle cell development	7.998894e-4
GO:0006396	RNA processing	8.037591e-4
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade	8.260939e-4
GO:0006972	hyperosmotic response	8.295850e-4
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	8.385988e-4
GO:0006936	muscle contraction	8.572512e-4
GO:0007140	male meiosis	8.824943e-4
GO:0061004	pattern specification involved in kidney development	9.119842e-4
GO:0051276	chromosome organization	9.244612e-4
GO:0030218	erythrocyte differentiation	9.639243e-4
GO:0002087	regulation of respiratory gaseous exchange by neurological system process	9.713805e-4
GO:0006600	creatine metabolic process	9.804068e-4
GO:0003329	pancreatic PP cell fate commitment	9.926612e-4
GO:0071474	cellular hyperosmotic response	9.926612e-4
GO:0003326	pancreatic A cell fate commitment	9.926612e-4
GO:0019048	virus-host interaction	1.011982e-3
GO:0000381	regulation of alternative nuclear mRNA splicing, via spliceosome	1.027162e-3
GO:0034101	erythrocyte homeostasis	1.039903e-3
GO:0030852	regulation of granulocyte differentiation	1.044714e-3
GO:0044403	symbiosis, encompassing mutualism through parasitism	1.062600e-3
GO:0055014	atrial cardiac muscle cell development	1.075514e-3
GO:0032509	endosome transport via multivesicular body sorting pathway	1.077627e-3
GO:0060696	regulation of phospholipid catabolic process	1.172346e-3
GO:0019441	tryptophan catabolic process to kynurenine	1.172346e-3
GO:0009651	response to salt stress	1.182342e-3
GO:0034453	microtubule anchoring	1.189936e-3
GO:0032703	negative regulation of interleukin-2 production	1.189936e-3
GO:0051454	intracellular pH elevation	1.208878e-3
GO:0009179	purine ribonucleoside diphosphate metabolic process	1.225926e-3
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	1.225926e-3
GO:0034114	regulation of heterotypic cell-cell adhesion	1.225926e-3
GO:0035966	response to topologically incorrect protein	1.232096e-3
GO:0035849	nephric duct elongation	1.241469e-3
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	1.241469e-3
GO:0035852	horizontal cell localization	1.241469e-3
GO:0035846	oviduct epithelium development	1.241469e-3
GO:0035847	uterine epithelium development	1.241469e-3
GO:0051791	medium-chain fatty acid metabolic process	1.243225e-3
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation	1.243225e-3
GO:0019751	polyol metabolic process	1.247470e-3
GO:0030239	myofibril assembly	1.267762e-3
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	1.335244e-3
GO:0002125	maternal aggressive behavior	1.350264e-3
GO:0044065	regulation of respiratory system process	1.354442e-3
GO:0070120	ciliary neurotrophic factor-mediated signaling pathway	1.395067e-3
GO:0046668	regulation of retinal cell programmed cell death	1.395067e-3
GO:0009992	cellular water homeostasis	1.413759e-3
GO:0055006	cardiac cell development	1.464528e-3
GO:0045989	positive regulation of striated muscle contraction	1.512299e-3
GO:0060445	branching involved in salivary gland morphogenesis	1.542859e-3
GO:0051584	regulation of dopamine uptake	1.591558e-3
GO:0031573	intra-S DNA damage checkpoint	1.591558e-3
GO:0006944	cellular membrane fusion	1.597346e-3
GO:0002577	regulation of antigen processing and presentation	1.600934e-3
GO:0035767	endothelial cell chemotaxis	1.652337e-3
GO:0044091	membrane biogenesis	1.668789e-3
GO:0035372	protein localization to microtubule	1.668789e-3
GO:0000027	ribosomal large subunit assembly	1.672495e-3
GO:0009159	deoxyribonucleoside monophosphate catabolic process	1.672495e-3
GO:0032469	endoplasmic reticulum calcium ion homeostasis	1.717833e-3
GO:0051788	response to misfolded protein	1.722886e-3
GO:0034621	cellular macromolecular complex subunit organization	1.725473e-3
GO:0035881	amacrine cell differentiation	1.795514e-3
GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	1.795514e-3
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	1.811233e-3
GO:0051883	killing of cells in other organism involved in symbiotic interaction	1.881765e-3
GO:0010957	negative regulation of vitamin D biosynthetic process	1.965015e-3
GO:0060745	mammary gland branching involved in pregnancy	1.983575e-3
GO:0006333	chromatin assembly or disassembly	2.011091e-3
GO:0031640	killing of cells of other organism	2.099990e-3
GO:0060389	pathway-restricted SMAD protein phosphorylation	2.099990e-3
GO:0042107	cytokine metabolic process	2.128788e-3
GO:0043056	forward locomotion	2.153489e-3
GO:0043576	regulation of respiratory gaseous exchange	2.158674e-3
GO:0015802	basic amino acid transport	2.263799e-3
GO:0019538	protein metabolic process	2.304711e-3
GO:0006916	anti-apoptosis	2.305353e-3
GO:0044267	cellular protein metabolic process	2.427602e-3
GO:0050850	positive regulation of calcium-mediated signaling	2.436347e-3
GO:0061025	membrane fusion	2.464617e-3
GO:0002518	lymphocyte chemotaxis across high endothelial venule	2.564221e-3
GO:0048631	regulation of skeletal muscle tissue growth	2.580927e-3
GO:0046963	3'-phosphoadenosine 5'-phosphosulfate transport	2.580927e-3
GO:0002432	granuloma formation	2.580927e-3
GO:0016557	peroxisome membrane biogenesis	2.580927e-3
GO:0048738	cardiac muscle tissue development	2.634589e-3
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	2.817497e-3
GO:0030099	myeloid cell differentiation	2.824870e-3
GO:0090083	regulation of inclusion body assembly	2.833251e-3
GO:0048661	positive regulation of smooth muscle cell proliferation	2.837206e-3
GO:0060596	mammary placode formation	2.861362e-3
GO:0006139	nucleobase-containing compound metabolic process	2.892326e-3
GO:0060298	positive regulation of sarcomere organization	2.981968e-3
GO:0046685	response to arsenic-containing substance	3.206790e-3
GO:0003278	apoptosis involved in heart morphogenesis	3.257379e-3
GO:0006105	succinate metabolic process	3.275948e-3
GO:0046619	optic placode formation involved in camera-type eye formation	3.317912e-3
GO:0010458	exit from mitosis	3.390359e-3
GO:0019835	cytolysis	3.400494e-3
GO:0050848	regulation of calcium-mediated signaling	3.441276e-3
GO:0035235	ionotropic glutamate receptor signaling pathway	3.490294e-3
GO:0035768	endothelial cell chemotaxis to fibroblast growth factor	3.569670e-3
GO:0035754	B cell chemotaxis	3.569670e-3
GO:0002449	lymphocyte mediated immunity	3.594853e-3
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	3.605505e-3
GO:0042113	B cell activation	3.695526e-3
GO:0003285	septum secundum development	3.736587e-3
GO:0006397	mRNA processing	3.871737e-3
GO:2000505	regulation of energy homeostasis	3.937445e-3
GO:0033239	negative regulation of cellular amine metabolic process	3.937445e-3
GO:0050869	negative regulation of B cell activation	3.947952e-3
GO:0019400	alditol metabolic process	3.966401e-3
GO:0045672	positive regulation of osteoclast differentiation	3.999932e-3
GO:0008380	RNA splicing	4.039047e-3
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	4.054211e-3
GO:0007040	lysosome organization	4.073759e-3
GO:0019530	taurine metabolic process	4.168401e-3
GO:0034605	cellular response to heat	4.218867e-3
GO:0030241	skeletal muscle myosin thick filament assembly	4.235257e-3
GO:0090304	nucleic acid metabolic process	4.288642e-3
GO:0042089	cytokine biosynthetic process	4.288833e-3
GO:0033058	directional locomotion	4.323721e-3
GO:0051792	medium-chain fatty acid biosynthetic process	4.565648e-3
GO:0021703	locus ceruleus development	4.565648e-3
GO:0035502	metanephric ureteric bud development	4.565648e-3
GO:0032463	negative regulation of protein homooligomerization	4.613736e-3
GO:0051568	histone H3-K4 methylation	4.657224e-3
GO:2000744	positive regulation of anterior head development	4.668428e-3
GO:0042094	interleukin-2 biosynthetic process	4.668428e-3
GO:0055012	ventricular cardiac muscle cell differentiation	4.716968e-3
GO:0007031	peroxisome organization	4.761070e-3
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	4.767414e-3
GO:0007215	glutamate signaling pathway	4.787586e-3
GO:0061205	paramesonephric duct development	4.821586e-3
GO:0051146	striated muscle cell differentiation	4.855661e-3
GO:0090174	organelle membrane fusion	4.911927e-3
GO:2001052	positive regulation of G1/S transition checkpoint	4.911927e-3
GO:0032915	positive regulation of transforming growth factor beta2 production	4.911927e-3
GO:0072574	hepatocyte proliferation	4.911927e-3
GO:0002194	hepatocyte cell migration	4.911927e-3
GO:0031497	chromatin assembly	4.944345e-3
GO:0044319	wound healing, spreading of cells	5.085100e-3
GO:0045047	protein targeting to ER	5.256484e-3
GO:0070669	response to interleukin-2	5.338843e-3
GO:0048143	astrocyte activation	5.693890e-3
GO:0042742	defense response to bacterium	5.752744e-3
GO:0032623	interleukin-2 production	5.770784e-3
GO:0060075	regulation of resting membrane potential	5.770784e-3
GO:0051580	regulation of neurotransmitter uptake	5.822632e-3
GO:0032652	regulation of interleukin-1 production	6.182739e-3
GO:0006289	nucleotide-excision repair	6.195806e-3
GO:0016192	vesicle-mediated transport	6.196004e-3
GO:0048680	positive regulation of axon regeneration	6.247252e-3
GO:0019853	L-ascorbic acid biosynthetic process	6.289465e-3
GO:0006568	tryptophan metabolic process	6.289465e-3
GO:0016071	mRNA metabolic process	6.513416e-3
GO:0060928	atrioventricular node cell development	6.532968e-3
GO:0060929	atrioventricular node cell fate commitment	6.532968e-3
GO:0015739	sialic acid transport	6.532968e-3
GO:0003342	proepicardium development	6.532968e-3
GO:0003168	cardiac Purkinje fiber cell differentiation	6.532968e-3
GO:0000715	nucleotide-excision repair, DNA damage recognition	6.544406e-3
GO:0060013	righting reflex	6.569768e-3
GO:0051574	positive regulation of histone H3-K9 methylation	6.569768e-3
GO:0007220	Notch receptor processing	6.604318e-3
GO:0001743	optic placode formation	6.652205e-3
GO:0006406	mRNA export from nucleus	6.852966e-3
GO:0045351	type I interferon biosynthetic process	6.962896e-3
GO:0042984	regulation of amyloid precursor protein biosynthetic process	6.962896e-3
GO:0019439	aromatic compound catabolic process	7.040622e-3
GO:0031330	negative regulation of cellular catabolic process	7.153607e-3
GO:0070189	kynurenine metabolic process	7.163623e-3
GO:0032769	negative regulation of monooxygenase activity	7.163623e-3
GO:0060347	heart trabecula formation	7.164235e-3
GO:0032651	regulation of interleukin-1 beta production	7.168104e-3
GO:0001779	natural killer cell differentiation	7.174078e-3
GO:0007258	JUN phosphorylation	7.221633e-3
GO:0072081	specification of nephron tubule identity	7.221633e-3
GO:0032692	negative regulation of interleukin-1 production	7.228642e-3
GO:0035051	cardiac cell differentiation	7.481150e-3
GO:0048872	homeostasis of number of cells	7.629594e-3
GO:0010040	response to iron(II) ion	7.737725e-3
GO:0060396	growth hormone receptor signaling pathway	7.787344e-3
GO:0048002	antigen processing and presentation of peptide antigen	7.855785e-3
GO:2000741	positive regulation of mesenchymal stem cell differentiation	7.915801e-3
GO:0048251	elastic fiber assembly	7.915801e-3
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	7.915801e-3
GO:0002507	tolerance induction	7.944400e-3
GO:0043412	macromolecule modification	8.074814e-3
GO:0014706	striated muscle tissue development	8.074974e-3
GO:0048009	insulin-like growth factor receptor signaling pathway	8.106625e-3
GO:0016926	protein desumoylation	8.199586e-3
GO:0006566	threonine metabolic process	8.199586e-3
GO:0006278	RNA-dependent DNA replication	8.217118e-3
GO:0033634	positive regulation of cell-cell adhesion mediated by integrin	8.279989e-3
GO:0045650	negative regulation of macrophage differentiation	8.279989e-3
GO:0015860	purine nucleoside transport	8.279989e-3
GO:0043457	regulation of cellular respiration	8.370228e-3
GO:0070541	response to platinum ion	8.421688e-3
GO:0051593	response to folic acid	8.517226e-3
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	8.542203e-3
GO:0070858	negative regulation of bile acid biosynthetic process	8.547890e-3
GO:0046341	CDP-diacylglycerol metabolic process	8.547890e-3
GO:0006464	protein modification process	8.760884e-3
GO:0007023	post-chaperonin tubulin folding pathway	8.781290e-3
GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	8.781290e-3
GO:0019836	hemolysis by symbiont of host erythrocytes	8.824130e-3
GO:0051622	negative regulation of norepinephrine uptake	9.105163e-3
GO:0051585	negative regulation of dopamine uptake	9.105163e-3
GO:0070495	negative regulation of thrombin receptor signaling pathway	9.105163e-3
GO:0033490	cholesterol biosynthetic process via lathosterol	9.105163e-3
GO:0050812	regulation of acyl-CoA biosynthetic process	9.105163e-3
GO:0051382	kinetochore assembly	9.105163e-3
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	9.163043e-3
GO:0014866	skeletal myofibril assembly	9.268968e-3
GO:0045988	negative regulation of striated muscle contraction	9.354576e-3
GO:0071378	cellular response to growth hormone stimulus	9.354576e-3
GO:0046709	IDP catabolic process	9.579107e-3
GO:0046032	ADP catabolic process	9.579107e-3
GO:0060215	primitive hemopoiesis	9.747905e-3
GO:0043001	Golgi to plasma membrane protein transport	9.747905e-3
GO:0046449	creatinine metabolic process	9.782138e-3
GO:0090096	positive regulation of metanephric cap mesenchymal cell proliferation	1.000568e-2
GO:0035162	embryonic hemopoiesis	1.009404e-2
GO:0055002	striated muscle cell development	1.028016e-2
GO:0043550	regulation of lipid kinase activity	1.031478e-2
GO:0050685	positive regulation of mRNA processing	1.042134e-2
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	1.047631e-2
GO:0046670	positive regulation of retinal cell programmed cell death	1.049956e-2
GO:0008626	induction of apoptosis by granzyme	1.049956e-2
GO:0000966	RNA 5'-end processing	1.049956e-2
GO:0002525	acute inflammatory response to non-antigenic stimulus	1.049956e-2
GO:0060537	muscle tissue development	1.057856e-2
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	1.058309e-2
GO:0002312	B cell activation involved in immune response	1.059174e-2
GO:0035313	wound healing, spreading of epidermal cells	1.075312e-2
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	1.076476e-2
GO:0071594	thymocyte aggregation	1.076476e-2
GO:0046967	cytosol to ER transport	1.076476e-2
GO:0033979	box H/ACA snoRNA metabolic process	1.076476e-2
GO:0019060	intracellular transport of viral proteins in host cell	1.076476e-2
GO:0006284	base-excision repair	1.077581e-2
GO:0006612	protein targeting to membrane	1.079170e-2
GO:0072086	specification of loop of Henle identity	1.089977e-2
GO:0006071	glycerol metabolic process	1.090540e-2
GO:0031547	brain-derived neurotrophic factor receptor signaling pathway	1.096725e-2
GO:0006996	organelle organization	1.114522e-2
GO:0007286	spermatid development	1.127711e-2
GO:0060174	limb bud formation	1.140236e-2
GO:0051545	negative regulation of elastin biosynthetic process	1.155194e-2
GO:0090321	positive regulation of chylomicron remnant clearance	1.155194e-2
GO:2000002	negative regulation of DNA damage checkpoint	1.155194e-2
GO:0022004	midbrain-hindbrain boundary maturation during brain development	1.155194e-2
GO:0090319	positive regulation of chylomicron remodeling	1.155194e-2
GO:0006709	progesterone catabolic process	1.155194e-2
GO:0009249	protein lipoylation	1.155194e-2
GO:0021551	central nervous system morphogenesis	1.155194e-2
GO:0021588	cerebellum formation	1.155194e-2
GO:0046834	lipid phosphorylation	1.175326e-2
GO:0072194	kidney smooth muscle tissue development	1.185591e-2
GO:0010820	positive regulation of T cell chemotaxis	1.190579e-2
GO:0034622	cellular macromolecular complex assembly	1.201262e-2
GO:0022408	negative regulation of cell-cell adhesion	1.204131e-2
GO:0070346	positive regulation of fat cell proliferation	1.209538e-2
GO:0048672	positive regulation of collateral sprouting	1.209538e-2
GO:0051612	negative regulation of serotonin uptake	1.209538e-2
GO:0070935	3'-UTR-mediated mRNA stabilization	1.211635e-2
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	1.211635e-2
GO:0060900	embryonic camera-type eye formation	1.214357e-2
GO:0010799	regulation of peptidyl-threonine phosphorylation	1.214357e-2
GO:0006281	DNA repair	1.217114e-2
GO:0060046	regulation of acrosome reaction	1.238314e-2
GO:0034447	very-low-density lipoprotein particle clearance	1.238314e-2
GO:0071544	diphosphoinositol polyphosphate catabolic process	1.246604e-2
GO:0060806	negative regulation of cell differentiation involved in embryonic placenta development	1.246604e-2
GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity	1.246604e-2
GO:0006930	substrate-dependent cell migration, cell extension	1.246604e-2
GO:0018364	peptidyl-glutamine methylation	1.246604e-2
GO:0032691	negative regulation of interleukin-1 beta production	1.252455e-2
GO:0051764	actin crosslink formation	1.261017e-2
GO:0000255	allantoin metabolic process	1.261017e-2
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	1.272010e-2
GO:0031069	hair follicle morphogenesis	1.288344e-2
GO:0032743	positive regulation of interleukin-2 production	1.294218e-2
GO:2000406	positive regulation of T cell migration	1.311871e-2
GO:0043299	leukocyte degranulation	1.321322e-2
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	1.323807e-2
GO:0060272	embryonic skeletal joint morphogenesis	1.324672e-2
GO:0002676	regulation of chronic inflammatory response	1.325595e-2
GO:0002691	regulation of cellular extravasation	1.340549e-2
GO:0072161	mesenchymal cell differentiation involved in kidney development	1.344559e-2
GO:0032984	macromolecular complex disassembly	1.356863e-2
GO:0055007	cardiac muscle cell differentiation	1.363165e-2
GO:0030719	P granule organization	1.384645e-2
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	1.406981e-2
GO:0009074	aromatic amino acid family catabolic process	1.419094e-2
GO:0034661	ncRNA catabolic process	1.442685e-2
GO:0009744	response to sucrose stimulus	1.442685e-2
GO:0015817	histidine transport	1.449348e-2
GO:0048668	collateral sprouting	1.449348e-2
GO:0019322	pentose biosynthetic process	1.449348e-2
GO:0046544	development of secondary male sexual characteristics	1.450657e-2
GO:0051013	microtubule severing	1.450657e-2
GO:0034214	protein hexamerization	1.450657e-2
GO:0033625	positive regulation of integrin activation	1.450657e-2
GO:0070672	response to interleukin-15	1.451848e-2
GO:0060648	mammary gland bud morphogenesis	1.451848e-2
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	1.451848e-2
GO:0045065	cytotoxic T cell differentiation	1.451848e-2
GO:0030101	natural killer cell activation	1.453080e-2
GO:0048293	regulation of isotype switching to IgE isotypes	1.465049e-2
GO:0060081	membrane hyperpolarization	1.476167e-2
GO:0006897	endocytosis	1.488221e-2
GO:0055009	atrial cardiac muscle tissue morphogenesis	1.500725e-2
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	1.511575e-2
GO:0000245	spliceosome assembly	1.515524e-2
GO:0006302	double-strand break repair	1.524079e-2
GO:0002483	antigen processing and presentation of endogenous peptide antigen	1.531715e-2
GO:0006376	mRNA splice site selection	1.554719e-2
GO:0072195	kidney smooth muscle cell differentiation	1.576385e-2
GO:0072105	ureteric peristalsis	1.576385e-2
GO:0072530	purine-containing compound transmembrane transport	1.586011e-2
GO:0070371	ERK1 and ERK2 cascade	1.586011e-2
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	1.606771e-2
GO:0015931	nucleobase-containing compound transport	1.617598e-2
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	1.618408e-2
GO:0043309	regulation of eosinophil degranulation	1.643034e-2