Novel motif:39

name:	motif39_CCAAGT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0032501	multicellular organismal process	1.913577e-15
GO:0002695	negative regulation of leukocyte activation	1.496243e-13
GO:0050896	response to stimulus	1.625313e-12
GO:0051250	negative regulation of lymphocyte activation	2.168784e-12
GO:0009653	anatomical structure morphogenesis	1.367254e-11
GO:0043252	sodium-independent organic anion transport	1.857695e-11
GO:0050866	negative regulation of cell activation	2.029004e-11
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	9.936072e-11
GO:0032502	developmental process	2.151458e-10
GO:2001021	negative regulation of response to DNA damage stimulus	3.596554e-10
GO:0051336	regulation of hydrolase activity	4.466500e-10
GO:0007275	multicellular organismal development	5.372223e-10
GO:0010035	response to inorganic substance	5.527772e-10
GO:0051249	regulation of lymphocyte activation	8.058078e-10
GO:0048731	system development	1.319211e-9
GO:0072358	cardiovascular system development	1.344199e-9
GO:0002683	negative regulation of immune system process	1.447292e-9
GO:0014075	response to amine stimulus	1.664264e-9
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	1.740799e-9
GO:0042221	response to chemical stimulus	3.524697e-9
GO:0010038	response to metal ion	3.814447e-9
GO:0048856	anatomical structure development	3.866240e-9
GO:0031099	regeneration	5.201267e-9
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	5.752119e-9
GO:0001101	response to acid	5.757006e-9
GO:0060574	intestinal epithelial cell maturation	6.726882e-9
GO:0043200	response to amino acid stimulus	6.764348e-9
GO:0002694	regulation of leukocyte activation	9.143225e-9
GO:0007154	cell communication	1.009048e-8
GO:0019836	hemolysis by symbiont of host erythrocytes	1.099256e-8
GO:0019805	quinolinate biosynthetic process	1.142081e-8
GO:0051659	maintenance of mitochondrion location	1.169077e-8
GO:0043067	regulation of programmed cell death	1.210957e-8
GO:0042981	regulation of apoptosis	1.516821e-8
GO:0051716	cellular response to stimulus	1.543758e-8
GO:0019853	L-ascorbic acid biosynthetic process	1.578945e-8
GO:0002828	regulation of type 2 immune response	1.778865e-8
GO:0023052	signaling	1.933785e-8
GO:0043009	chordate embryonic development	1.937738e-8
GO:0006950	response to stress	1.980374e-8
GO:0051657	maintenance of organelle location	2.449003e-8
GO:0070541	response to platinum ion	2.565166e-8
GO:0050789	regulation of biological process	2.680545e-8
GO:0030241	skeletal muscle myosin thick filament assembly	2.710352e-8
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	2.717158e-8
GO:0048513	organ development	2.775003e-8
GO:0044419	interspecies interaction between organisms	3.688014e-8
GO:0010941	regulation of cell death	4.774124e-8
GO:0009792	embryo development ending in birth or egg hatching	5.846023e-8
GO:0009605	response to external stimulus	6.112058e-8
GO:0050790	regulation of catalytic activity	6.312216e-8
GO:0032689	negative regulation of interferon-gamma production	8.337044e-8
GO:0007165	signal transduction	8.584024e-8
GO:0022414	reproductive process	8.606054e-8
GO:0000003	reproduction	8.921270e-8
GO:0030261	chromosome condensation	9.523203e-8
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	1.021978e-7
GO:0032910	regulation of transforming growth factor beta3 production	1.089013e-7
GO:0045109	intermediate filament organization	1.139146e-7
GO:0046874	quinolinate metabolic process	1.240611e-7
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	1.302159e-7
GO:0006182	cGMP biosynthetic process	1.373893e-7
GO:0032703	negative regulation of interleukin-2 production	1.685801e-7
GO:0060548	negative regulation of cell death	2.056874e-7
GO:0034104	negative regulation of tissue remodeling	2.121322e-7
GO:0043316	cytotoxic T cell degranulation	2.156737e-7
GO:0050865	regulation of cell activation	2.253507e-7
GO:0070663	regulation of leukocyte proliferation	2.461361e-7
GO:0002830	positive regulation of type 2 immune response	2.521459e-7
GO:0046851	negative regulation of bone remodeling	2.953855e-7
GO:0050794	regulation of cellular process	3.147544e-7
GO:0045779	negative regulation of bone resorption	3.455077e-7
GO:0048583	regulation of response to stimulus	3.496732e-7
GO:0016032	viral reproduction	3.510015e-7
GO:0010269	response to selenium ion	3.546954e-7
GO:0002376	immune system process	3.763470e-7
GO:0046578	regulation of Ras protein signal transduction	4.260691e-7
GO:0002831	regulation of response to biotic stimulus	4.293698e-7
GO:0014866	skeletal myofibril assembly	4.687891e-7
GO:0006952	defense response	4.765460e-7
GO:0035051	cardiac cell differentiation	4.838931e-7
GO:0044238	primary metabolic process	4.956145e-7
GO:0048739	cardiac muscle fiber development	5.028188e-7
GO:0032916	positive regulation of transforming growth factor beta3 production	5.401919e-7
GO:0032731	positive regulation of interleukin-1 beta production	5.430934e-7
GO:0002682	regulation of immune system process	5.636824e-7
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	5.675432e-7
GO:0070664	negative regulation of leukocyte proliferation	5.699046e-7
GO:0065007	biological regulation	5.925495e-7
GO:0009888	tissue development	6.641345e-7
GO:0006936	muscle contraction	6.791969e-7
GO:0032732	positive regulation of interleukin-1 production	7.265787e-7
GO:0050863	regulation of T cell activation	7.609309e-7
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	8.878396e-7
GO:0048468	cell development	9.113136e-7
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	9.355606e-7
GO:0045187	regulation of circadian sleep/wake cycle, sleep	9.417546e-7
GO:0052548	regulation of endopeptidase activity	1.028442e-6
GO:0050955	thermoception	1.037715e-6
GO:0043154	negative regulation of caspase activity	1.048657e-6
GO:0010466	negative regulation of peptidase activity	1.051718e-6
GO:0001834	trophectodermal cell proliferation	1.277581e-6
GO:0012501	programmed cell death	1.354913e-6
GO:0050868	negative regulation of T cell activation	1.458015e-6
GO:0006935	chemotaxis	1.523029e-6
GO:0048869	cellular developmental process	1.619648e-6
GO:0042157	lipoprotein metabolic process	1.793171e-6
GO:0060118	vestibular receptor cell development	1.932865e-6
GO:0006807	nitrogen compound metabolic process	1.960257e-6
GO:0065009	regulation of molecular function	1.989624e-6
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	2.024389e-6
GO:0032855	positive regulation of Rac GTPase activity	2.038229e-6
GO:0043069	negative regulation of programmed cell death	2.038566e-6
GO:0048646	anatomical structure formation involved in morphogenesis	2.108658e-6
GO:0030154	cell differentiation	2.183183e-6
GO:0006955	immune response	2.216579e-6
GO:0046078	dUMP metabolic process	2.298331e-6
GO:0032318	regulation of Ras GTPase activity	2.463412e-6
GO:0034754	cellular hormone metabolic process	2.516590e-6
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	2.617631e-6
GO:0042127	regulation of cell proliferation	2.624317e-6
GO:0007059	chromosome segregation	2.706226e-6
GO:0007507	heart development	2.779403e-6
GO:2000116	regulation of cysteine-type endopeptidase activity	2.785112e-6
GO:0022410	circadian sleep/wake cycle process	2.786022e-6
GO:0052547	regulation of peptidase activity	2.828506e-6
GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	2.847621e-6
GO:0019222	regulation of metabolic process	2.906686e-6
GO:0002478	antigen processing and presentation of exogenous peptide antigen	3.389182e-6
GO:0007623	circadian rhythm	3.392046e-6
GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	3.431712e-6
GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	3.431712e-6
GO:0001501	skeletal system development	3.448735e-6
GO:0061043	regulation of vascular wound healing	3.535207e-6
GO:0061309	cardiac neural crest cell development involved in outflow tract morphogenesis	3.808125e-6
GO:0042752	regulation of circadian rhythm	3.889180e-6
GO:0009887	organ morphogenesis	4.461483e-6
GO:0000279	M phase	4.499797e-6
GO:0055013	cardiac muscle cell development	4.779940e-6
GO:0006139	nucleobase-containing compound metabolic process	4.795931e-6
GO:0051345	positive regulation of hydrolase activity	4.945175e-6
GO:0001657	ureteric bud development	4.952897e-6
GO:0032989	cellular component morphogenesis	5.029142e-6
GO:0009074	aromatic amino acid family catabolic process	5.178383e-6
GO:0043094	cellular metabolic compound salvage	5.208954e-6
GO:0009611	response to wounding	5.331618e-6
GO:0002832	negative regulation of response to biotic stimulus	5.489479e-6
GO:0055003	cardiac myofibril assembly	5.840850e-6
GO:0051085	chaperone mediated protein folding requiring cofactor	5.851027e-6
GO:0043066	negative regulation of apoptosis	6.090957e-6
GO:0042940	D-amino acid transport	6.134246e-6
GO:0007584	response to nutrient	6.365632e-6
GO:0032320	positive regulation of Ras GTPase activity	6.489800e-6
GO:0007049	cell cycle	6.577235e-6
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	6.671320e-6
GO:0019088	immortalization of host cell by virus	6.987186e-6
GO:0006231	dTMP biosynthetic process	6.987186e-6
GO:0055007	cardiac muscle cell differentiation	7.083668e-6
GO:0002697	regulation of immune effector process	7.124977e-6
GO:0051346	negative regulation of hydrolase activity	7.279260e-6
GO:0006820	anion transport	7.291911e-6
GO:0019363	pyridine nucleotide biosynthetic process	7.617003e-6
GO:0042745	circadian sleep/wake cycle	7.699374e-6
GO:0006725	cellular aromatic compound metabolic process	7.704690e-6
GO:0010811	positive regulation of cell-substrate adhesion	8.404798e-6
GO:0006915	apoptosis	8.481292e-6
GO:0048514	blood vessel morphogenesis	9.308834e-6
GO:0008624	induction of apoptosis by extracellular signals	9.404948e-6
GO:0050688	regulation of defense response to virus	9.589764e-6
GO:0002251	organ or tissue specific immune response	9.733848e-6
GO:0034641	cellular nitrogen compound metabolic process	9.902638e-6
GO:0001667	ameboidal cell migration	1.021876e-5
GO:0048512	circadian behavior	1.061340e-5
GO:0010043	response to zinc ion	1.115783e-5
GO:0090291	negative regulation of osteoclast proliferation	1.158257e-5
GO:2000347	positive regulation of hepatocyte proliferation	1.158257e-5
GO:2000349	negative regulation of CD40 signaling pathway	1.158257e-5
GO:0072573	tolerance induction to lipopolysaccharide	1.158257e-5
GO:0034148	negative regulation of toll-like receptor 5 signaling pathway	1.158257e-5
GO:0070429	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.158257e-5
GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.158257e-5
GO:0048518	positive regulation of biological process	1.228789e-5
GO:0048769	sarcomerogenesis	1.248283e-5
GO:0051056	regulation of small GTPase mediated signal transduction	1.271669e-5
GO:0031397	negative regulation of protein ubiquitination	1.371831e-5
GO:0002069	columnar/cuboidal epithelial cell maturation	1.384049e-5
GO:0006508	proteolysis	1.388029e-5
GO:0031100	organ regeneration	1.421404e-5
GO:0060252	positive regulation of glial cell proliferation	1.427641e-5
GO:0007005	mitochondrion organization	1.436519e-5
GO:0035691	macrophage migration inhibitory factor signaling pathway	1.482468e-5
GO:0051701	interaction with host	1.544014e-5
GO:0008219	cell death	1.584614e-5
GO:0006569	tryptophan catabolic process	1.591059e-5
GO:0060126	somatotropin secreting cell differentiation	1.618062e-5
GO:0007093	mitotic cell cycle checkpoint	1.635228e-5
GO:0033273	response to vitamin	1.715903e-5
GO:0046635	positive regulation of alpha-beta T cell activation	1.720548e-5
GO:0035270	endocrine system development	1.723365e-5
GO:0016265	death	1.778633e-5
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	1.782938e-5
GO:0006082	organic acid metabolic process	1.789314e-5
GO:0030239	myofibril assembly	1.808898e-5
GO:0000302	response to reactive oxygen species	1.852832e-5
GO:0043547	positive regulation of GTPase activity	1.908413e-5
GO:0007051	spindle organization	1.941160e-5
GO:0010628	positive regulation of gene expression	2.026547e-5
GO:0046850	regulation of bone remodeling	2.120484e-5
GO:0006568	tryptophan metabolic process	2.123071e-5
GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint	2.141092e-5
GO:0046634	regulation of alpha-beta T cell activation	2.152231e-5
GO:0008347	glial cell migration	2.261437e-5
GO:0050869	negative regulation of B cell activation	2.537617e-5
GO:0080090	regulation of primary metabolic process	2.548519e-5
GO:0010604	positive regulation of macromolecule metabolic process	2.602623e-5
GO:0010625	positive regulation of Schwann cell proliferation	2.603514e-5
GO:0032944	regulation of mononuclear cell proliferation	2.640269e-5
GO:0045124	regulation of bone resorption	2.680528e-5
GO:0032233	positive regulation of actin filament bundle assembly	2.755408e-5
GO:0045590	negative regulation of regulatory T cell differentiation	2.838442e-5
GO:0009162	deoxyribonucleoside monophosphate metabolic process	2.841633e-5
GO:0031032	actomyosin structure organization	2.897545e-5
GO:0048522	positive regulation of cellular process	2.955868e-5
GO:0014032	neural crest cell development	3.067928e-5
GO:0061008	hepaticobiliary system development	3.111825e-5
GO:0048729	tissue morphogenesis	3.158792e-5
GO:0042753	positive regulation of circadian rhythm	3.191369e-5
GO:0061298	retina vasculature development in camera-type eye	3.198242e-5
GO:0051704	multi-organism process	3.207856e-5
GO:0051004	regulation of lipoprotein lipase activity	3.241495e-5
GO:0019439	aromatic compound catabolic process	3.242109e-5
GO:0019752	carboxylic acid metabolic process	3.267056e-5
GO:0050670	regulation of lymphocyte proliferation	3.378244e-5
GO:0022415	viral reproductive process	3.434268e-5
GO:0008207	C21-steroid hormone metabolic process	3.466069e-5
GO:0070779	D-aspartate import	3.531412e-5
GO:0043031	negative regulation of macrophage activation	3.638160e-5
GO:0001701	in utero embryonic development	3.728906e-5
GO:0060322	head development	3.894808e-5
GO:0001756	somitogenesis	3.947057e-5
GO:0010761	fibroblast migration	3.979776e-5
GO:0040011	locomotion	3.986821e-5
GO:0002385	mucosal immune response	4.444057e-5
GO:0045630	positive regulation of T-helper 2 cell differentiation	4.462155e-5
GO:0048519	negative regulation of biological process	4.479953e-5
GO:0008283	cell proliferation	4.505547e-5
GO:0065008	regulation of biological quality	4.564476e-5
GO:0060351	cartilage development involved in endochondral bone morphogenesis	4.583005e-5
GO:0061053	somite development	4.624917e-5
GO:0001836	release of cytochrome c from mitochondria	4.647206e-5
GO:0050864	regulation of B cell activation	4.687507e-5
GO:0015742	alpha-ketoglutarate transport	4.711592e-5
GO:0010243	response to organic nitrogen	4.728217e-5
GO:0045621	positive regulation of lymphocyte differentiation	4.756370e-5
GO:0070670	response to interleukin-4	4.774099e-5
GO:0035023	regulation of Rho protein signal transduction	4.849371e-5
GO:0034135	regulation of toll-like receptor 2 signaling pathway	4.910933e-5
GO:0060323	head morphogenesis	5.039042e-5
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	5.219001e-5
GO:0033153	T cell receptor V(D)J recombination	5.258389e-5
GO:0001889	liver development	5.346571e-5
GO:0051045	negative regulation of membrane protein ectodomain proteolysis	5.389875e-5
GO:0010810	regulation of cell-substrate adhesion	5.416888e-5
GO:0007276	gamete generation	5.426388e-5
GO:0001954	positive regulation of cell-matrix adhesion	5.439500e-5
GO:0018874	benzoate metabolic process	5.469718e-5
GO:0040007	growth	5.479360e-5
GO:0048771	tissue remodeling	5.515745e-5
GO:0048644	muscle organ morphogenesis	5.548756e-5
GO:0044403	symbiosis, encompassing mutualism through parasitism	5.598222e-5
GO:0031570	DNA integrity checkpoint	5.598446e-5
GO:2000348	regulation of CD40 signaling pathway	5.606997e-5
GO:0010661	positive regulation of muscle cell apoptosis	5.606997e-5
GO:0042246	tissue regeneration	5.728436e-5
GO:0035435	phosphate ion transmembrane transport	5.906137e-5
GO:0043627	response to estrogen stimulus	5.933074e-5
GO:0048598	embryonic morphogenesis	6.035631e-5
GO:0016485	protein processing	6.154740e-5
GO:0003006	developmental process involved in reproduction	6.202057e-5
GO:0001957	intramembranous ossification	6.341217e-5
GO:0045581	negative regulation of T cell differentiation	6.396006e-5
GO:0009966	regulation of signal transduction	6.557582e-5
GO:0055086	nucleobase-containing small molecule metabolic process	6.598841e-5
GO:2000602	regulation of interphase of mitotic cell cycle	6.733303e-5
GO:0000077	DNA damage checkpoint	6.757293e-5
GO:0007585	respiratory gaseous exchange	6.763516e-5
GO:0048538	thymus development	6.907792e-5
GO:0009435	NAD biosynthetic process	7.026414e-5
GO:0042180	cellular ketone metabolic process	7.039490e-5
GO:0044249	cellular biosynthetic process	7.078466e-5
GO:0045103	intermediate filament-based process	7.094049e-5
GO:0043615	astrocyte cell migration	7.123297e-5
GO:0019884	antigen processing and presentation of exogenous antigen	7.254081e-5
GO:0001658	branching involved in ureteric bud morphogenesis	7.334806e-5
GO:0048539	bone marrow development	7.385590e-5
GO:0071780	mitotic cell cycle G2/M transition checkpoint	7.669767e-5
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	7.785481e-5
GO:0014015	positive regulation of gliogenesis	7.822451e-5
GO:0006954	inflammatory response	7.941835e-5
GO:0018009	N-terminal peptidyl-L-cysteine N-palmitoylation	8.033092e-5
GO:0001525	angiogenesis	8.097688e-5
GO:0031016	pancreas development	8.265964e-5
GO:0015711	organic anion transport	8.336739e-5
GO:0003012	muscle system process	8.356092e-5
GO:0061325	cell proliferation involved in outflow tract morphogenesis	8.412224e-5
GO:0060127	prolactin secreting cell differentiation	8.412224e-5
GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis	8.412224e-5
GO:0009893	positive regulation of metabolic process	8.466376e-5
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	8.643356e-5
GO:0072224	metanephric glomerulus development	8.683236e-5
GO:0030237	female sex determination	8.720787e-5
GO:0043087	regulation of GTPase activity	8.785138e-5
GO:0060290	transdifferentiation	8.792819e-5
GO:0032652	regulation of interleukin-1 production	8.864838e-5
GO:0030240	skeletal muscle thin filament assembly	8.962975e-5
GO:0007168	receptor guanylyl cyclase signaling pathway	8.992451e-5
GO:0009124	nucleoside monophosphate biosynthetic process	9.020378e-5
GO:0060070	canonical Wnt receptor signaling pathway	9.352371e-5
GO:0032856	activation of Ras GTPase activity	9.469397e-5
GO:0042445	hormone metabolic process	9.719741e-5
GO:0032651	regulation of interleukin-1 beta production	9.785047e-5
GO:0001568	blood vessel development	9.809179e-5
GO:0045104	intermediate filament cytoskeleton organization	9.855523e-5
GO:0042542	response to hydrogen peroxide	1.000854e-4
GO:0010171	body morphogenesis	1.024919e-4
GO:0000087	M phase of mitotic cell cycle	1.026036e-4
GO:0007067	mitosis	1.030311e-4
GO:0022402	cell cycle process	1.031242e-4
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.047213e-4
GO:0007622	rhythmic behavior	1.060391e-4
GO:0015910	peroxisomal long-chain fatty acid import	1.065439e-4
GO:0006493	protein O-linked glycosylation	1.069961e-4
GO:0050795	regulation of behavior	1.077807e-4
GO:0035239	tube morphogenesis	1.095261e-4
GO:0060562	epithelial tube morphogenesis	1.097616e-4
GO:0055008	cardiac muscle tissue morphogenesis	1.134673e-4
GO:0060324	face development	1.144761e-4
GO:0008152	metabolic process	1.169130e-4
GO:0061307	cardiac neural crest cell differentiation involved in heart development	1.174690e-4
GO:0046512	sphingosine biosynthetic process	1.185385e-4
GO:0009855	determination of bilateral symmetry	1.189174e-4
GO:0042703	menstruation	1.190754e-4
GO:0019101	female somatic sex determination	1.190754e-4
GO:0051239	regulation of multicellular organismal process	1.196935e-4
GO:0048285	organelle fission	1.204245e-4
GO:0006434	seryl-tRNA aminoacylation	1.231872e-4
GO:0048738	cardiac muscle tissue development	1.297054e-4
GO:0009799	specification of symmetry	1.303492e-4
GO:0060700	regulation of ribonuclease activity	1.307589e-4
GO:0032321	positive regulation of Rho GTPase activity	1.329136e-4
GO:0046638	positive regulation of alpha-beta T cell differentiation	1.397530e-4
GO:0031667	response to nutrient levels	1.412338e-4
GO:0006435	threonyl-tRNA aminoacylation	1.423738e-4
GO:0016055	Wnt receptor signaling pathway	1.450141e-4
GO:0045582	positive regulation of T cell differentiation	1.474429e-4
GO:0043900	regulation of multi-organism process	1.480201e-4
GO:0046483	heterocycle metabolic process	1.504471e-4
GO:0000819	sister chromatid segregation	1.525007e-4
GO:0031575	mitotic cell cycle G1/S transition checkpoint	1.530946e-4
GO:0051496	positive regulation of stress fiber assembly	1.575769e-4
GO:0002074	extraocular skeletal muscle development	1.600029e-4
GO:0045589	regulation of regulatory T cell differentiation	1.608000e-4
GO:0006586	indolalkylamine metabolic process	1.622570e-4
GO:0015810	aspartate transport	1.656507e-4
GO:0032101	regulation of response to external stimulus	1.676160e-4
GO:0032845	negative regulation of homeostatic process	1.690683e-4
GO:0072404	signal transduction involved in G1/S transition checkpoint	1.697481e-4
GO:0060255	regulation of macromolecule metabolic process	1.699615e-4
GO:0072422	signal transduction involved in DNA damage checkpoint	1.761667e-4
GO:0044281	small molecule metabolic process	1.890701e-4
GO:0033962	cytoplasmic mRNA processing body assembly	1.896283e-4
GO:0010666	positive regulation of cardiac muscle cell apoptosis	1.917728e-4
GO:0010927	cellular component assembly involved in morphogenesis	2.016070e-4
GO:0070098	chemokine-mediated signaling pathway	2.033831e-4
GO:0006427	histidyl-tRNA aminoacylation	2.053055e-4
GO:0060973	cell migration involved in heart development	2.064086e-4
GO:0045329	carnitine biosynthetic process	2.158606e-4
GO:0043420	anthranilate metabolic process	2.179764e-4
GO:0034516	response to vitamin B6	2.179764e-4
GO:0060442	branching involved in prostate gland morphogenesis	2.205486e-4
GO:0019953	sexual reproduction	2.207265e-4
GO:0071779	G1/S transition checkpoint	2.222362e-4
GO:0019442	tryptophan catabolic process to acetyl-CoA	2.276984e-4
GO:0023019	signal transduction involved in regulation of gene expression	2.328725e-4
GO:0050870	positive regulation of T cell activation	2.447614e-4
GO:0045786	negative regulation of cell cycle	2.488650e-4
GO:0071732	cellular response to nitric oxide	2.498591e-4
GO:0032663	regulation of interleukin-2 production	2.582300e-4
GO:0060675	ureteric bud morphogenesis	2.597802e-4
GO:0033693	neurofilament bundle assembly	2.619106e-4
GO:0019359	nicotinamide nucleotide biosynthetic process	2.624596e-4
GO:0006414	translational elongation	2.630484e-4
GO:0009058	biosynthetic process	2.642446e-4
GO:0033124	regulation of GTP catabolic process	2.656421e-4
GO:0048545	response to steroid hormone stimulus	2.688347e-4
GO:0031323	regulation of cellular metabolic process	2.734808e-4
GO:0072395	signal transduction involved in cell cycle checkpoint	2.790819e-4
GO:0071712	ER-associated misfolded protein catabolic process	2.816654e-4
GO:0055001	muscle cell development	2.889773e-4
GO:0050672	negative regulation of lymphocyte proliferation	2.902565e-4
GO:0043170	macromolecule metabolic process	2.905494e-4
GO:0060764	cell-cell signaling involved in mammary gland development	3.070371e-4
GO:0044003	modification by symbiont of host morphology or physiology	3.071366e-4
GO:0003417	growth plate cartilage development	3.098891e-4
GO:0050747	positive regulation of lipoprotein metabolic process	3.117593e-4
GO:0032700	negative regulation of interleukin-17 production	3.190335e-4
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	3.201682e-4
GO:0048609	multicellular organismal reproductive process	3.225006e-4
GO:0001503	ossification	3.230567e-4
GO:0010033	response to organic substance	3.361492e-4
GO:0016338	calcium-independent cell-cell adhesion	3.363655e-4
GO:0060415	muscle tissue morphogenesis	3.376397e-4
GO:0006642	triglyceride mobilization	3.498977e-4
GO:0051246	regulation of protein metabolic process	3.501662e-4
GO:0035470	positive regulation of vascular wound healing	3.519485e-4
GO:0032754	positive regulation of interleukin-5 production	3.619528e-4
GO:0060325	face morphogenesis	3.663182e-4
GO:0070849	response to epidermal growth factor stimulus	3.667104e-4
GO:0045620	negative regulation of lymphocyte differentiation	3.676930e-4
GO:0050678	regulation of epithelial cell proliferation	3.728889e-4
GO:0071353	cellular response to interleukin-4	3.773799e-4
GO:0045785	positive regulation of cell adhesion	3.800685e-4
GO:0032495	response to muramyl dipeptide	3.834948e-4
GO:0048608	reproductive structure development	3.847161e-4
GO:0016337	cell-cell adhesion	3.863471e-4
GO:0061138	morphogenesis of a branching epithelium	3.869082e-4
GO:0007283	spermatogenesis	3.870398e-4
GO:0001944	vasculature development	3.872989e-4
GO:0051234	establishment of localization	3.910071e-4
GO:0034654	nucleobase-containing compound biosynthetic process	3.937165e-4
GO:0070682	proteasome regulatory particle assembly	3.938152e-4
GO:0032720	negative regulation of tumor necrosis factor production	3.954553e-4
GO:2000345	regulation of hepatocyte proliferation	3.991357e-4
GO:0030048	actin filament-based movement	4.049042e-4
GO:0048523	negative regulation of cellular process	4.070930e-4
GO:0009112	nucleobase metabolic process	4.073167e-4
GO:0046395	carboxylic acid catabolic process	4.213600e-4
GO:0050951	sensory perception of temperature stimulus	4.217777e-4
GO:0002426	immunoglobulin production in mucosal tissue	4.217777e-4
GO:0018993	somatic sex determination	4.255410e-4
GO:0001763	morphogenesis of a branching structure	4.397354e-4
GO:0048754	branching morphogenesis of a tube	4.397403e-4
GO:0044237	cellular metabolic process	4.449170e-4
GO:0002009	morphogenesis of an epithelium	4.508696e-4
GO:0008284	positive regulation of cell proliferation	4.549957e-4
GO:0006520	cellular amino acid metabolic process	4.600559e-4
GO:0055093	response to hyperoxia	4.616570e-4
GO:0006627	protein processing involved in protein targeting to mitochondrion	4.655220e-4
GO:0071294	cellular response to zinc ion	4.655220e-4
GO:0051251	positive regulation of lymphocyte activation	4.678698e-4
GO:0050727	regulation of inflammatory response	4.691411e-4
GO:0001553	luteinization	4.727666e-4
GO:0001817	regulation of cytokine production	4.744543e-4
GO:0070372	regulation of ERK1 and ERK2 cascade	4.775376e-4
GO:0007411	axon guidance	4.788640e-4
GO:0001922	B-1 B cell homeostasis	4.799967e-4
GO:0018130	heterocycle biosynthetic process	4.814148e-4
GO:0060336	negative regulation of interferon-gamma-mediated signaling pathway	4.822923e-4
GO:0046686	response to cadmium ion	4.851802e-4
GO:0021516	dorsal spinal cord development	4.870957e-4
GO:0043403	skeletal muscle tissue regeneration	4.882283e-4
GO:0050690	regulation of defense response to virus by virus	4.907404e-4
GO:0018199	peptidyl-glutamine modification	4.913730e-4
GO:0030916	otic vesicle formation	4.929306e-4
GO:0046394	carboxylic acid biosynthetic process	5.022086e-4
GO:0070374	positive regulation of ERK1 and ERK2 cascade	5.056692e-4
GO:0006670	sphingosine metabolic process	5.103710e-4
GO:0048546	digestive tract morphogenesis	5.151554e-4
GO:0070741	response to interleukin-6	5.184454e-4
GO:0009991	response to extracellular stimulus	5.205643e-4
GO:0030049	muscle filament sliding	5.221475e-4
GO:0042159	lipoprotein catabolic process	5.476354e-4
GO:0014038	regulation of Schwann cell differentiation	5.546525e-4
GO:0009123	nucleoside monophosphate metabolic process	5.572364e-4
GO:0030168	platelet activation	5.629446e-4
GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	5.710843e-4
GO:0008637	apoptotic mitochondrial changes	5.767937e-4
GO:0002906	negative regulation of mature B cell apoptosis	5.779766e-4
GO:0021915	neural tube development	5.832257e-4
GO:0030198	extracellular matrix organization	5.834681e-4
GO:0021999	neural plate anterior/posterior regionalization	5.862815e-4
GO:0045619	regulation of lymphocyte differentiation	5.875855e-4
GO:0045071	negative regulation of viral genome replication	6.052386e-4
GO:0060907	positive regulation of macrophage cytokine production	6.107423e-4
GO:0002246	wound healing involved in inflammatory response	6.115251e-4
GO:0001934	positive regulation of protein phosphorylation	6.178153e-4
GO:0048589	developmental growth	6.335159e-4
GO:0006941	striated muscle contraction	6.336227e-4
GO:0002520	immune system development	6.383076e-4
GO:0051094	positive regulation of developmental process	6.403901e-4
GO:0030903	notochord development	6.459291e-4
GO:0022614	membrane to membrane docking	6.518093e-4
GO:0042448	progesterone metabolic process	6.520080e-4
GO:0033121	regulation of purine nucleotide catabolic process	6.523695e-4
GO:0060346	bone trabecula formation	6.548520e-4
GO:0042364	water-soluble vitamin biosynthetic process	6.551934e-4
GO:0048511	rhythmic process	6.596163e-4
GO:0009165	nucleotide biosynthetic process	6.725824e-4
GO:0061061	muscle structure development	6.734346e-4
GO:0019674	NAD metabolic process	6.834474e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0048240	sperm capacitation	9.256051e-17
GO:0006952	defense response	3.221315e-15
GO:0042742	defense response to bacterium	9.358304e-12
GO:0045071	negative regulation of viral genome replication	1.048234e-11
GO:0048525	negative regulation of viral reproduction	1.508052e-11
GO:0008207	C21-steroid hormone metabolic process	1.811907e-11
GO:0045869	negative regulation of retroviral genome replication	3.152400e-11
GO:0006954	inflammatory response	5.660861e-11
GO:0006950	response to stress	1.404699e-10
GO:0055114	oxidation-reduction process	8.337727e-10
GO:0006629	lipid metabolic process	1.460008e-9
GO:0045091	regulation of retroviral genome replication	1.719718e-9
GO:0051704	multi-organism process	2.863028e-9
GO:0045947	negative regulation of translational initiation	2.946634e-9
GO:0050896	response to stimulus	3.344043e-9
GO:2000121	regulation of removal of superoxide radicals	3.509472e-9
GO:0009566	fertilization	3.965070e-9
GO:0042953	lipoprotein transport	4.122228e-9
GO:0060613	fat pad development	4.292101e-9
GO:0051707	response to other organism	7.502409e-9
GO:0034754	cellular hormone metabolic process	1.207230e-8
GO:0045834	positive regulation of lipid metabolic process	1.638213e-8
GO:0006436	tryptophanyl-tRNA aminoacylation	1.794987e-8
GO:0006704	glucocorticoid biosynthetic process	2.014183e-8
GO:0010883	regulation of lipid storage	2.271868e-8
GO:0022414	reproductive process	2.286646e-8
GO:0010155	regulation of proton transport	3.129407e-8
GO:0045006	DNA deamination	3.483656e-8
GO:0009617	response to bacterium	3.562307e-8
GO:0015911	plasma membrane long-chain fatty acid transport	3.914440e-8
GO:0006700	C21-steroid hormone biosynthetic process	4.004376e-8
GO:0050710	negative regulation of cytokine secretion	6.080076e-8
GO:0006810	transport	7.415077e-8
GO:0044255	cellular lipid metabolic process	7.560716e-8
GO:0008202	steroid metabolic process	7.805982e-8
GO:0045738	negative regulation of DNA repair	8.154250e-8
GO:0051023	regulation of immunoglobulin secretion	9.586326e-8
GO:0009607	response to biotic stimulus	1.024485e-7
GO:0003006	developmental process involved in reproduction	1.230373e-7
GO:0000003	reproduction	1.308338e-7
GO:0007276	gamete generation	1.464102e-7
GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	1.876329e-7
GO:2001038	regulation of cellular response to drug	1.876329e-7
GO:2000685	positive regulation of cellular response to X-ray	1.876329e-7
GO:0035988	chondrocyte proliferation	1.876329e-7
GO:0031052	chromosome breakage	1.876329e-7
GO:0035978	histone H2A-S139 phosphorylation	1.876329e-7
GO:0003131	mesodermal-endodermal cell signaling	1.876329e-7
GO:0010743	regulation of macrophage derived foam cell differentiation	2.209874e-7
GO:0051234	establishment of localization	5.531319e-7
GO:0030325	adrenal gland development	5.655060e-7
GO:0045190	isotype switching	5.823103e-7
GO:0008211	glucocorticoid metabolic process	6.593929e-7
GO:0019433	triglyceride catabolic process	6.707538e-7
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	8.125745e-7
GO:0061041	regulation of wound healing	8.507477e-7
GO:0051179	localization	8.584210e-7
GO:0007512	adult heart development	9.278535e-7
GO:0006641	triglyceride metabolic process	9.881875e-7
GO:0048515	spermatid differentiation	1.192587e-6
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	1.230751e-6
GO:0015860	purine nucleoside transport	1.232841e-6
GO:0090322	regulation of superoxide metabolic process	1.235157e-6
GO:0080134	regulation of response to stress	1.719414e-6
GO:0051883	killing of cells in other organism involved in symbiotic interaction	2.056716e-6
GO:0042448	progesterone metabolic process	2.062857e-6
GO:0002366	leukocyte activation involved in immune response	2.133247e-6
GO:0072527	pyrimidine-containing compound metabolic process	2.254409e-6
GO:0019836	hemolysis by symbiont of host erythrocytes	2.285154e-6
GO:0046689	response to mercury ion	2.369437e-6
GO:0045137	development of primary sexual characteristics	2.423061e-6
GO:0031640	killing of cells of other organism	2.646187e-6
GO:0019953	sexual reproduction	3.020601e-6
GO:0031953	negative regulation of protein autophosphorylation	3.810992e-6
GO:0072091	regulation of stem cell proliferation	3.941190e-6
GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	4.049357e-6
GO:2000648	positive regulation of stem cell proliferation	4.070771e-6
GO:0045348	positive regulation of MHC class II biosynthetic process	4.183471e-6
GO:0006091	generation of precursor metabolites and energy	4.677549e-6
GO:0015980	energy derivation by oxidation of organic compounds	4.961688e-6
GO:0051240	positive regulation of multicellular organismal process	5.431307e-6
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	5.517247e-6
GO:2000275	regulation of oxidative phosphorylation uncoupler activity	5.547801e-6
GO:0006642	triglyceride mobilization	5.878317e-6
GO:0051235	maintenance of location	5.970533e-6
GO:0050709	negative regulation of protein secretion	6.106622e-6
GO:0050873	brown fat cell differentiation	6.191973e-6
GO:0046963	3'-phosphoadenosine 5'-phosphosulfate transport	6.476937e-6
GO:0043901	negative regulation of multi-organism process	6.480902e-6
GO:0017148	negative regulation of translation	6.839147e-6
GO:0006310	DNA recombination	6.900717e-6
GO:0002449	lymphocyte mediated immunity	6.979026e-6
GO:0051657	maintenance of organelle location	6.980994e-6
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	7.249415e-6
GO:0051645	Golgi localization	7.312349e-6
GO:0051659	maintenance of mitochondrion location	7.383423e-6
GO:0071447	cellular response to hydroperoxide	7.392329e-6
GO:0048557	embryonic digestive tract morphogenesis	7.418973e-6
GO:0060100	positive regulation of phagocytosis, engulfment	7.960608e-6
GO:0031034	myosin filament assembly	8.296823e-6
GO:0046503	glycerolipid catabolic process	8.596976e-6
GO:0046464	acylglycerol catabolic process	8.702620e-6
GO:0032649	regulation of interferon-gamma production	9.083411e-6
GO:0048305	immunoglobulin secretion	9.512398e-6
GO:0045649	regulation of macrophage differentiation	9.612947e-6
GO:0071356	cellular response to tumor necrosis factor	9.631147e-6
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	1.003862e-5
GO:0007548	sex differentiation	1.013518e-5
GO:0010817	regulation of hormone levels	1.051762e-5
GO:0018904	organic ether metabolic process	1.119600e-5
GO:0001993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine	1.149747e-5
GO:0002312	B cell activation involved in immune response	1.167039e-5
GO:0030261	chromosome condensation	1.312445e-5
GO:0021548	pons development	1.441209e-5
GO:0043410	positive regulation of MAPKKK cascade	1.557151e-5
GO:0050820	positive regulation of coagulation	1.578638e-5
GO:0048584	positive regulation of response to stimulus	1.629859e-5
GO:0051239	regulation of multicellular organismal process	1.638181e-5
GO:0032656	regulation of interleukin-13 production	1.652963e-5
GO:2000465	regulation of glycogen (starch) synthase activity	1.682308e-5
GO:0030194	positive regulation of blood coagulation	1.747382e-5
GO:0045069	regulation of viral genome replication	1.807201e-5
GO:0007283	spermatogenesis	1.847662e-5
GO:0070541	response to platinum ion	1.849439e-5
GO:0044281	small molecule metabolic process	1.892137e-5
GO:2000677	regulation of transcription regulatory region DNA binding	1.904741e-5
GO:0046330	positive regulation of JNK cascade	1.967794e-5
GO:0048519	negative regulation of biological process	1.989228e-5
GO:0002676	regulation of chronic inflammatory response	1.993055e-5
GO:0007623	circadian rhythm	2.015398e-5
GO:0044403	symbiosis, encompassing mutualism through parasitism	2.018746e-5
GO:0010744	positive regulation of macrophage derived foam cell differentiation	2.034348e-5
GO:0045650	negative regulation of macrophage differentiation	2.079074e-5
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	2.094201e-5
GO:0021754	facial nucleus development	2.094201e-5
GO:0001817	regulation of cytokine production	2.258386e-5
GO:0060008	Sertoli cell differentiation	2.342701e-5
GO:0007281	germ cell development	2.387741e-5
GO:0002686	negative regulation of leukocyte migration	2.388382e-5
GO:0048609	multicellular organismal reproductive process	2.391599e-5
GO:0045638	negative regulation of myeloid cell differentiation	2.416098e-5
GO:0045940	positive regulation of steroid metabolic process	2.460356e-5
GO:0072529	pyrimidine-containing compound catabolic process	2.472043e-5
GO:0006662	glycerol ether metabolic process	2.602704e-5
GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	2.711262e-5
GO:0006446	regulation of translational initiation	2.814221e-5
GO:2000334	positive regulation of blood microparticle formation	2.987275e-5
GO:0032269	negative regulation of cellular protein metabolic process	3.084088e-5
GO:0008610	lipid biosynthetic process	3.104691e-5
GO:0019752	carboxylic acid metabolic process	3.262175e-5
GO:0009972	cytidine deamination	3.317172e-5
GO:0048512	circadian behavior	3.329524e-5
GO:0002544	chronic inflammatory response	3.571043e-5
GO:0016447	somatic recombination of immunoglobulin gene segments	3.612004e-5
GO:0001775	cell activation	3.718068e-5
GO:0019722	calcium-mediated signaling	3.850216e-5
GO:0043589	skin morphogenesis	3.854355e-5
GO:0044130	negative regulation of growth of symbiont in host	3.871469e-5
GO:0042753	positive regulation of circadian rhythm	3.922630e-5
GO:0010529	negative regulation of transposition	4.098014e-5
GO:0070383	DNA cytosine deamination	4.098014e-5
GO:0045988	negative regulation of striated muscle contraction	4.166458e-5
GO:0002682	regulation of immune system process	4.193400e-5
GO:0043900	regulation of multi-organism process	4.402207e-5
GO:0019216	regulation of lipid metabolic process	4.461359e-5
GO:0006639	acylglycerol metabolic process	4.533136e-5
GO:0042221	response to chemical stimulus	4.565035e-5
GO:0002440	production of molecular mediator of immune response	4.565661e-5
GO:0006930	substrate-dependent cell migration, cell extension	4.590518e-5
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	4.590518e-5
GO:0042180	cellular ketone metabolic process	4.654374e-5
GO:0050818	regulation of coagulation	4.679518e-5
GO:0008406	gonad development	4.799728e-5
GO:0065007	biological regulation	4.949234e-5
GO:0007286	spermatid development	4.993407e-5
GO:0051100	negative regulation of binding	5.099388e-5
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	5.267397e-5
GO:0031649	heat generation	5.458907e-5
GO:0030193	regulation of blood coagulation	5.508422e-5
GO:0045346	regulation of MHC class II biosynthetic process	5.666069e-5
GO:0002443	leukocyte mediated immunity	5.724751e-5
GO:2000467	positive regulation of glycogen (starch) synthase activity	5.803536e-5
GO:0019218	regulation of steroid metabolic process	5.907541e-5
GO:0019724	B cell mediated immunity	5.920796e-5
GO:0051716	cellular response to stimulus	6.026126e-5
GO:0034612	response to tumor necrosis factor	6.028603e-5
GO:0001818	negative regulation of cytokine production	6.333735e-5
GO:0043252	sodium-independent organic anion transport	6.388759e-5
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	6.452795e-5
GO:0002678	positive regulation of chronic inflammatory response	6.700750e-5
GO:0044242	cellular lipid catabolic process	6.743005e-5
GO:0014003	oligodendrocyte development	6.904915e-5
GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine	6.911801e-5
GO:0051970	negative regulation of transmission of nerve impulse	7.066485e-5
GO:0016064	immunoglobulin mediated immune response	7.391673e-5
GO:0006082	organic acid metabolic process	7.486870e-5
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	7.596105e-5
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	7.716397e-5
GO:0043309	regulation of eosinophil degranulation	7.773855e-5
GO:0006909	phagocytosis	7.838665e-5
GO:0048545	response to steroid hormone stimulus	7.866824e-5
GO:0003096	renal sodium ion transport	8.430475e-5
GO:0032782	bile acid secretion	8.430475e-5
GO:0044419	interspecies interaction between organisms	8.526540e-5
GO:0016445	somatic diversification of immunoglobulins	8.715247e-5
GO:0010466	negative regulation of peptidase activity	8.824523e-5
GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure	9.248921e-5
GO:0048566	embryonic digestive tract development	9.725780e-5
GO:0051224	negative regulation of protein transport	9.875376e-5
GO:0030643	cellular phosphate ion homeostasis	1.041249e-4
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	1.053448e-4
GO:0002831	regulation of response to biotic stimulus	1.061384e-4
GO:0046325	negative regulation of glucose import	1.081352e-4
GO:0019915	lipid storage	1.100773e-4
GO:0034383	low-density lipoprotein particle clearance	1.136167e-4
GO:0032689	negative regulation of interferon-gamma production	1.136167e-4
GO:0042574	retinal metabolic process	1.139889e-4
GO:0050805	negative regulation of synaptic transmission	1.155698e-4
GO:0090402	oncogene-induced senescence	1.167864e-4
GO:2000774	positive regulation of cellular senescence	1.167864e-4
GO:0035986	senescence-associated heterochromatin focus formation	1.167864e-4
GO:0006955	immune response	1.178682e-4
GO:0032680	regulation of tumor necrosis factor production	1.188197e-4
GO:0010888	negative regulation of lipid storage	1.235303e-4
GO:0043277	apoptotic cell clearance	1.253282e-4
GO:0046546	development of primary male sexual characteristics	1.266370e-4
GO:0045333	cellular respiration	1.275629e-4
GO:0007622	rhythmic behavior	1.287847e-4
GO:0044341	sodium-dependent phosphate transport	1.304155e-4
GO:0050830	defense response to Gram-positive bacterium	1.310766e-4
GO:0042445	hormone metabolic process	1.324616e-4
GO:0009719	response to endogenous stimulus	1.332840e-4
GO:0031952	regulation of protein autophosphorylation	1.391937e-4
GO:0001985	negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure	1.406325e-4
GO:0008584	male gonad development	1.418536e-4
GO:0051101	regulation of DNA binding	1.439326e-4
GO:2000772	regulation of cellular senescence	1.505670e-4
GO:0032655	regulation of interleukin-12 production	1.528829e-4
GO:0045321	leukocyte activation	1.557378e-4
GO:0032653	regulation of interleukin-10 production	1.581870e-4
GO:0071221	cellular response to bacterial lipopeptide	1.616473e-4
GO:0051248	negative regulation of protein metabolic process	1.642393e-4
GO:0006942	regulation of striated muscle contraction	1.642795e-4
GO:0007009	plasma membrane organization	1.661457e-4
GO:0032733	positive regulation of interleukin-10 production	1.678332e-4
GO:0060123	regulation of growth hormone secretion	1.688924e-4
GO:0031645	negative regulation of neurological system process	1.691841e-4
GO:0051241	negative regulation of multicellular organismal process	1.725644e-4
GO:0002377	immunoglobulin production	1.856779e-4
GO:0051640	organelle localization	1.862834e-4
GO:0030728	ovulation	1.883724e-4
GO:0008286	insulin receptor signaling pathway	1.899038e-4
GO:2000377	regulation of reactive oxygen species metabolic process	1.929755e-4
GO:0051651	maintenance of location in cell	1.932815e-4
GO:0051586	positive regulation of dopamine uptake	1.933734e-4
GO:2000279	negative regulation of DNA biosynthetic process	1.975378e-4
GO:0032735	positive regulation of interleukin-12 production	1.976302e-4
GO:0010885	regulation of cholesterol storage	1.979352e-4
GO:0006929	substrate-dependent cell migration	2.003171e-4
GO:0045444	fat cell differentiation	2.064946e-4
GO:0060341	regulation of cellular localization	2.071986e-4
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	2.147742e-4
GO:0001906	cell killing	2.171274e-4
GO:0010829	negative regulation of glucose transport	2.198343e-4
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	2.199526e-4
GO:0032642	regulation of chemokine production	2.217645e-4
GO:0010460	positive regulation of heart rate	2.240122e-4
GO:0002285	lymphocyte activation involved in immune response	2.254579e-4
GO:0048518	positive regulation of biological process	2.257953e-4
GO:0021678	third ventricle development	2.274691e-4
GO:0006418	tRNA aminoacylation for protein translation	2.279013e-4
GO:0009725	response to hormone stimulus	2.287179e-4
GO:0048743	positive regulation of skeletal muscle fiber development	2.296932e-4
GO:0006206	pyrimidine base metabolic process	2.351913e-4
GO:0043467	regulation of generation of precursor metabolites and energy	2.395051e-4
GO:0044330	canonical Wnt receptor signaling pathway involved in positive regulation of wound healing	2.468561e-4
GO:0044328	canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration	2.468561e-4
GO:0044329	canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion	2.468561e-4
GO:0015872	dopamine transport	2.490377e-4
GO:0045065	cytotoxic T cell differentiation	2.506765e-4
GO:2000353	positive regulation of endothelial cell apoptosis	2.521973e-4
GO:0009611	response to wounding	2.582686e-4
GO:0043392	negative regulation of DNA binding	2.617139e-4
GO:0050994	regulation of lipid catabolic process	2.645432e-4
GO:0010906	regulation of glucose metabolic process	2.666960e-4
GO:0002740	negative regulation of cytokine secretion involved in immune response	2.681555e-4
GO:0033993	response to lipid	2.723583e-4
GO:0042474	middle ear morphogenesis	2.750988e-4
GO:0070257	positive regulation of mucus secretion	2.776062e-4
GO:2000679	positive regulation of transcription regulatory region DNA binding	2.845250e-4
GO:2000779	regulation of double-strand break repair	2.905987e-4
GO:0070255	regulation of mucus secretion	2.991349e-4
GO:0006638	neutral lipid metabolic process	3.148263e-4
GO:0017126	nucleologenesis	3.195591e-4
GO:0034381	plasma lipoprotein particle clearance	3.225207e-4
GO:0031668	cellular response to extracellular stimulus	3.232285e-4
GO:0002762	negative regulation of myeloid leukocyte differentiation	3.305001e-4
GO:0050789	regulation of biological process	3.323981e-4
GO:0051181	cofactor transport	3.443864e-4
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	3.479157e-4
GO:0051583	dopamine uptake	3.479157e-4
GO:0051461	positive regulation of corticotropin secretion	3.479880e-4
GO:2000683	regulation of cellular response to X-ray	3.483875e-4
GO:0001983	baroreceptor response to increased systemic arterial blood pressure	3.483875e-4
GO:0006643	membrane lipid metabolic process	3.551417e-4
GO:0007605	sensory perception of sound	3.582495e-4
GO:0002526	acute inflammatory response	3.594518e-4
GO:0010884	positive regulation of lipid storage	3.656252e-4
GO:0010886	positive regulation of cholesterol storage	3.694158e-4
GO:0021682	nerve maturation	3.705797e-4
GO:0019482	beta-alanine metabolic process	3.705797e-4
GO:0002839	positive regulation of immune response to tumor cell	3.707239e-4
GO:0010033	response to organic substance	3.752610e-4
GO:0061037	negative regulation of cartilage development	3.957076e-4
GO:0060324	face development	3.964064e-4
GO:0010677	negative regulation of cellular carbohydrate metabolic process	3.980860e-4
GO:0071361	cellular response to ethanol	4.003476e-4
GO:0044062	regulation of excretion	4.178107e-4
GO:0071875	adrenergic receptor signaling pathway	4.178107e-4
GO:0045776	negative regulation of blood pressure	4.199172e-4
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	4.262151e-4
GO:0034114	regulation of heterotypic cell-cell adhesion	4.262151e-4
GO:0002376	immune system process	4.373671e-4
GO:0010989	negative regulation of low-density lipoprotein particle clearance	4.395413e-4
GO:0021592	fourth ventricle development	4.403905e-4
GO:0010896	regulation of triglyceride catabolic process	4.430927e-4
GO:0045777	positive regulation of blood pressure	4.519954e-4
GO:0071496	cellular response to external stimulus	4.595812e-4
GO:0021539	subthalamus development	4.918659e-4
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	4.926548e-4
GO:0002689	negative regulation of leukocyte chemotaxis	4.976490e-4
GO:0060009	Sertoli cell development	4.979795e-4
GO:0048625	myoblast cell fate commitment	5.003390e-4
GO:0002837	regulation of immune response to tumor cell	5.005378e-4
GO:0014013	regulation of gliogenesis	5.037991e-4
GO:0006665	sphingolipid metabolic process	5.108128e-4
GO:0071705	nitrogen compound transport	5.113130e-4
GO:0050707	regulation of cytokine secretion	5.190574e-4
GO:0090096	positive regulation of metanephric cap mesenchymal cell proliferation	5.224699e-4
GO:0022900	electron transport chain	5.233746e-4
GO:0010872	regulation of cholesterol esterification	5.329050e-4
GO:0051701	interaction with host	5.349520e-4
GO:0046784	intronless viral mRNA export from host nucleus	5.388265e-4
GO:0015858	nucleoside transport	5.388265e-4
GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback	5.423237e-4
GO:0000070	mitotic sister chromatid segregation	5.452888e-4
GO:0021846	cell proliferation in forebrain	5.467368e-4
GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine	5.534284e-4
GO:0010987	negative regulation of high-density lipoprotein particle clearance	5.586816e-4
GO:0010897	negative regulation of triglyceride catabolic process	5.586816e-4
GO:0006910	phagocytosis, recognition	5.602474e-4
GO:0000819	sister chromatid segregation	5.607428e-4
GO:0061048	negative regulation of branching involved in lung morphogenesis	5.616874e-4
GO:0045994	positive regulation of translational initiation by iron	5.616874e-4
GO:0034116	positive regulation of heterotypic cell-cell adhesion	5.616874e-4
GO:0002037	negative regulation of L-glutamate transport	5.616874e-4
GO:0010605	negative regulation of macromolecule metabolic process	5.647678e-4
GO:0006259	DNA metabolic process	5.692472e-4
GO:0048523	negative regulation of cellular process	5.927027e-4
GO:0051154	negative regulation of striated muscle cell differentiation	5.950631e-4
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	5.954043e-4
GO:0072061	inner medullary collecting duct development	6.010745e-4
GO:0072060	outer medullary collecting duct development	6.010745e-4
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	6.010745e-4
GO:0010608	posttranscriptional regulation of gene expression	6.093383e-4
GO:0022610	biological adhesion	6.166498e-4
GO:2000242	negative regulation of reproductive process	6.211894e-4
GO:0033057	multicellular organismal reproductive behavior	6.220551e-4
GO:0055062	phosphate ion homeostasis	6.229707e-4
GO:0070873	regulation of glycogen metabolic process	6.263475e-4
GO:0010873	positive regulation of cholesterol esterification	6.468357e-4
GO:0006694	steroid biosynthetic process	6.523038e-4
GO:0002250	adaptive immune response	6.571347e-4
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	6.574024e-4
GO:0043388	positive regulation of DNA binding	6.607801e-4
GO:0035411	catenin import into nucleus	6.615799e-4
GO:0008016	regulation of heart contraction	6.640249e-4
GO:0052547	regulation of peptidase activity	6.733081e-4
GO:0051125	regulation of actin nucleation	6.839800e-4
GO:0007155	cell adhesion	6.843885e-4
GO:0010982	regulation of high-density lipoprotein particle clearance	6.959958e-4
GO:0030730	sequestering of triglyceride	6.959958e-4
GO:0048610	cellular process involved in reproduction	7.439297e-4
GO:0046520	sphingoid biosynthetic process	7.456829e-4
GO:0003073	regulation of systemic arterial blood pressure	7.618467e-4
GO:0010647	positive regulation of cell communication	7.663565e-4
GO:0045924	regulation of female receptivity	7.775003e-4
GO:0045428	regulation of nitric oxide biosynthetic process	7.886019e-4
GO:0002200	somatic diversification of immune receptors	7.963766e-4
GO:0050673	epithelial cell proliferation	8.088097e-4
GO:0009892	negative regulation of metabolic process	8.139542e-4
GO:0030168	platelet activation	8.178330e-4
GO:0071222	cellular response to lipopolysaccharide	8.307632e-4
GO:0042990	regulation of transcription factor import into nucleus	8.335608e-4
GO:0006109	regulation of carbohydrate metabolic process	8.393686e-4
GO:0007621	negative regulation of female receptivity	8.774061e-4
GO:0031424	keratinization	8.787813e-4
GO:0031507	heterochromatin formation	8.916219e-4
GO:0030317	sperm motility	8.925291e-4
GO:0046626	regulation of insulin receptor signaling pathway	8.959976e-4
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	8.984767e-4
GO:0032847	regulation of cellular pH reduction	9.041098e-4
GO:0051937	catecholamine transport	9.160783e-4
GO:0046006	regulation of activated T cell proliferation	9.176404e-4
GO:0002237	response to molecule of bacterial origin	9.196628e-4
GO:0048251	elastic fiber assembly	9.236453e-4
GO:0032274	gonadotropin secretion	9.262237e-4
GO:0048546	digestive tract morphogenesis	9.390764e-4
GO:0010675	regulation of cellular carbohydrate metabolic process	9.452180e-4
GO:0050792	regulation of viral reproduction	9.477216e-4
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	9.668328e-4
GO:0046513	ceramide biosynthetic process	9.681476e-4
GO:0002252	immune effector process	1.009108e-3
GO:0002833	positive regulation of response to biotic stimulus	1.019039e-3
GO:0032496	response to lipopolysaccharide	1.021865e-3
GO:0071702	organic substance transport	1.039935e-3
GO:0046466	membrane lipid catabolic process	1.040516e-3
GO:0006911	phagocytosis, engulfment	1.058270e-3
GO:0070995	NADPH oxidation	1.060869e-3
GO:0034435	cholesterol esterification	1.064356e-3
GO:0007126	meiosis	1.089700e-3
GO:0060312	regulation of blood vessel remodeling	1.102125e-3
GO:0006323	DNA packaging	1.102166e-3
GO:0015850	organic alcohol transport	1.103783e-3
GO:0044092	negative regulation of molecular function	1.115456e-3
GO:0032879	regulation of localization	1.146735e-3
GO:0043408	regulation of MAPKKK cascade	1.157357e-3
GO:0071219	cellular response to molecule of bacterial origin	1.158921e-3
GO:0032673	regulation of interleukin-4 production	1.163197e-3
GO:0060334	regulation of interferon-gamma-mediated signaling pathway	1.170724e-3
GO:0001978	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback	1.170724e-3
GO:0051321	meiotic cell cycle	1.196545e-3
GO:0032944	regulation of mononuclear cell proliferation	1.197917e-3
GO:0034440	lipid oxidation	1.200928e-3
GO:0051046	regulation of secretion	1.204566e-3
GO:0072053	renal inner medulla development	1.209654e-3
GO:0017144	drug metabolic process	1.212523e-3
GO:0030853	negative regulation of granulocyte differentiation	1.227343e-3
GO:0044140	negative regulation of growth of symbiont on or near host surface	1.229405e-3
GO:0006844	acyl carnitine transport	1.229405e-3
GO:0061099	negative regulation of protein tyrosine kinase activity	1.239297e-3
GO:0033194	response to hydroperoxide	1.239862e-3
GO:0060556	regulation of vitamin D biosynthetic process	1.241751e-3
GO:0046889	positive regulation of lipid biosynthetic process	1.241979e-3
GO:0002125	maternal aggressive behavior	1.242981e-3
GO:0007016	cytoskeletal anchoring at plasma membrane	1.247846e-3
GO:0032101	regulation of response to external stimulus	1.262556e-3
GO:0008152	metabolic process	1.302808e-3
GO:0050954	sensory perception of mechanical stimulus	1.309330e-3
GO:0002281	macrophage activation involved in immune response	1.318589e-3
GO:0044003	modification by symbiont of host morphology or physiology	1.318732e-3
GO:0006721	terpenoid metabolic process	1.336570e-3
GO:0002115	store-operated calcium entry	1.338815e-3
GO:0071803	positive regulation of podosome assembly	1.338815e-3
GO:0070201	regulation of establishment of protein localization	1.352329e-3
GO:0009112	nucleobase metabolic process	1.355197e-3
GO:0032859	activation of Ral GTPase activity	1.374018e-3
GO:0019229	regulation of vasoconstriction	1.391195e-3
GO:0051346	negative regulation of hydrolase activity	1.413544e-3
GO:0060010	Sertoli cell fate commitment	1.447370e-3
GO:0016098	monoterpenoid metabolic process	1.447370e-3
GO:0002275	myeloid cell activation involved in immune response	1.456831e-3
GO:0050670	regulation of lymphocyte proliferation	1.458528e-3
GO:0021570	rhombomere 4 development	1.472465e-3
GO:0006931	substrate-dependent cell migration, cell attachment to substrate	1.472465e-3
GO:2000273	positive regulation of receptor activity	1.486241e-3
GO:0046661	male sex differentiation	1.488937e-3
GO:0032456	endocytic recycling	1.492372e-3
GO:0071103	DNA conformation change	1.496730e-3
GO:0080135	regulation of cellular response to stress	1.506987e-3
GO:0009615	response to virus	1.514813e-3
GO:0032229	negative regulation of synaptic transmission, GABAergic	1.547561e-3
GO:0072054	renal outer medulla development	1.553244e-3
GO:0015931	nucleobase-containing compound transport	1.561218e-3
GO:0051984	positive regulation of chromosome segregation	1.575022e-3
GO:0034498	early endosome to Golgi transport	1.575022e-3
GO:0006420	arginyl-tRNA aminoacylation	1.575022e-3
GO:0034337	RNA folding	1.577503e-3
GO:0032722	positive regulation of chemokine production	1.580694e-3
GO:0046135	pyrimidine nucleoside catabolic process	1.582664e-3
GO:0000027	ribosomal large subunit assembly	1.597917e-3
GO:0046293	formaldehyde biosynthetic process	1.597917e-3
GO:0031324	negative regulation of cellular metabolic process	1.598134e-3
GO:0060262	negative regulation of N-terminal protein palmitoylation	1.598346e-3
GO:0016482	cytoplasmic transport	1.598346e-3
GO:0051103	DNA ligation involved in DNA repair	1.606554e-3
GO:2001021	negative regulation of response to DNA damage stimulus	1.608504e-3
GO:0008633	activation of pro-apoptotic gene products	1.611530e-3
GO:0010740	positive regulation of intracellular protein kinase cascade	1.623353e-3
GO:0072659	protein localization in plasma membrane	1.640238e-3
GO:0015884	folic acid transport	1.642494e-3
GO:0043200	response to amino acid stimulus	1.656273e-3
GO:0006937	regulation of muscle contraction	1.686224e-3
GO:0023056	positive regulation of signaling	1.688740e-3
GO:0044106	cellular amine metabolic process	1.689608e-3
GO:0010810	regulation of cell-substrate adhesion	1.699643e-3
GO:0032501	multicellular organismal process	1.721464e-3
GO:0010646	regulation of cell communication	1.778175e-3
GO:0045429	positive regulation of nitric oxide biosynthetic process	1.789279e-3
GO:0032674	regulation of interleukin-5 production	1.814861e-3