MCL coexpression mm9:949

Phase1 CAGE Peaks

	Short description
Mm9::chr13:5860749..5860772,+	p2@Klf6
Mm9::chr13:5860776..5860796,+	p1@Klf6
Mm9::chr13:5860872..5860883,+	p3@Klf6
Mm9::chr19:5850004..5850014,-	p@chr19:5850004..5850014 -
Mm9::chr5:140267510..140267555,+	p2@Mafk
Mm9::chr7:29162636..29162650,-	p@chr7:29162636..29162650 -
Mm9::chr7:29164266..29164282,-	p1@Zfp36
Mm9::chr8:73222830..73222844,+	p1@Jund

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0006355	regulation of transcription, DNA-dependent	0.000846250591911452
GO:0006351	transcription, DNA-dependent	0.000846250591911452
GO:0032774	RNA biosynthetic process	0.000846250591911452
GO:0003677	DNA binding	0.000846250591911452
GO:0045449	regulation of transcription	0.000846250591911452
GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.000846250591911452
GO:0006350	transcription	0.000846250591911452
GO:0010468	regulation of gene expression	0.000846250591911452
GO:0031323	regulation of cellular metabolic process	0.000883418543246339
GO:0019222	regulation of metabolic process	0.000919415008920835
GO:0016070	RNA metabolic process	0.000927678990891804
GO:0010467	gene expression	0.00174457134770867
GO:0003676	nucleic acid binding	0.00177157416827755
GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.0021697329344756
GO:0046983	protein dimerization activity	0.0021697329344756
GO:0050794	regulation of cellular process	0.00256845552065455
GO:0050789	regulation of biological process	0.0037195622018551
GO:0065007	biological regulation	0.00517786401692624
GO:0051726	regulation of cell cycle	0.0053044587446759
GO:0043283	biopolymer metabolic process	0.00571734313471222
GO:0043565	sequence-specific DNA binding	0.00713917179461032
GO:0022402	cell cycle process	0.0112374307265607
GO:0043170	macromolecule metabolic process	0.0148121223912388
GO:0007049	cell cycle	0.0162530989024509
GO:0019221	cytokine and chemokine mediated signaling pathway	0.0184724840990229
GO:0003700	transcription factor activity	0.0198073286152921
GO:0044238	primary metabolic process	0.021900994017295
GO:0044237	cellular metabolic process	0.021900994017295

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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