MCL coexpression mm9:1025

Phase1 CAGE Peaks

	Short description
Mm9::chr10:51310245..51310270,-	p1@Fam162b
Mm9::chr10:51310279..51310303,-	p2@Fam162b
Mm9::chr11:8403889..8403913,-	p@chr11:8403889..8403913 -
Mm9::chr8:123606985..123607053,-	p1@1110050K14Rik
Mm9::chr8:123607738..123607759,+	p@chr8:123607738..123607759 +
Mm9::chr8:123608252..123608268,+	p1@Foxf1a
Mm9::chr9:75623162..75623185,+	p1@Bmp5

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0045198	establishment of epithelial cell polarity	0.0176214447361656
GO:0030859	polarized epithelial cell differentiation	0.0176214447361656
GO:0035089	establishment of apical/basal cell polarity	0.0176214447361656
GO:0045197	establishment and/or maintenance of epithelial cell polarity	0.0176214447361656
GO:0035088	establishment and/or maintenance of apical/basal cell polarity	0.0176214447361656
GO:0001738	morphogenesis of a polarized epithelium	0.0176214447361656
GO:0030010	establishment of cell polarity	0.0176214447361656
GO:0048566	embryonic gut development	0.0176214447361656
GO:0048565	gut development	0.0216849603820765
GO:0007163	establishment and/or maintenance of cell polarity	0.0260176733532009
GO:0001570	vasculogenesis	0.0285761028610465
GO:0030855	epithelial cell differentiation	0.0308432971942609
GO:0048568	embryonic organ development	0.0308432971942609
GO:0007179	transforming growth factor beta receptor signaling pathway	0.0325006961650463
GO:0048513	organ development	0.0325006961650463
GO:0051216	cartilage development	0.0325006961650463
GO:0030198	extracellular matrix organization and biogenesis	0.0363153402358759
GO:0030324	lung development	0.0370449151759794
GO:0030323	respiratory tube development	0.0370449151759794
GO:0048731	system development	0.0371793008965218
GO:0048869	cellular developmental process	0.0371793008965218
GO:0030154	cell differentiation	0.0371793008965218
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	0.0371793008965218
GO:0001503	ossification	0.0397919222532879
GO:0031214	biomineral formation	0.0397919222532879
GO:0043062	extracellular structure organization and biogenesis	0.0397919222532879
GO:0048856	anatomical structure development	0.0397919222532879
GO:0046849	bone remodeling	0.0397919222532879
GO:0048771	tissue remodeling	0.043510276184561
GO:0002009	morphogenesis of an epithelium	0.043510276184561
GO:0007275	multicellular organismal development	0.043510276184561

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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