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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0016242;negative regulation of macroautophagy;0.0156759784556345;76482!GO:0016241;regulation of macroautophagy;0.0156759784556345;76482!GO:0033344;cholesterol efflux;0.0156759784556345;76482!GO:0008158;hedgehog receptor activity;0.0156759784556345;76482!GO:0007041;lysosomal transport;0.0156759784556345;76482!GO:0008206;bile acid metabolic process;0.0156759784556345;76482!GO:0016236;macroautophagy;0.0156759784556345;76482!GO:0030301;cholesterol transport;0.0156759784556345;76482!GO:0015918;sterol transport;0.0156759784556345;76482!GO:0007034;vacuolar transport;0.0156759784556345;76482!GO:0042632;cholesterol homeostasis;0.0156759784556345;76482!GO:0055088;lipid homeostasis;0.0156759784556345;76482!GO:0055092;sterol homeostasis;0.0156759784556345;76482!GO:0006914;autophagy;0.0196872959981344;76482!}}
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0016242;negative regulation of macroautophagy;0.0156759784556345;76482!GO:0016241;regulation of macroautophagy;0.0156759784556345;76482!GO:0033344;cholesterol efflux;0.0156759784556345;76482!GO:0008158;hedgehog receptor activity;0.0156759784556345;76482!GO:0007041;lysosomal transport;0.0156759784556345;76482!GO:0008206;bile acid metabolic process;0.0156759784556345;76482!GO:0016236;macroautophagy;0.0156759784556345;76482!GO:0030301;cholesterol transport;0.0156759784556345;76482!GO:0015918;sterol transport;0.0156759784556345;76482!GO:0007034;vacuolar transport;0.0156759784556345;76482!GO:0042632;cholesterol homeostasis;0.0156759784556345;76482!GO:0055088;lipid homeostasis;0.0156759784556345;76482!GO:0055092;sterol homeostasis;0.0156759784556345;76482!GO:0006914;autophagy;0.0196872959981344;76482!
}}

Revision as of 11:41, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr13:59924433..59924504,-p1@Zcchc6
Mm9::chr18:12327220..12327300,+p1@3110002H16Rik
Mm9::chr4:10934688..10934781,-p1@Plekhf2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0016242negative regulation of macroautophagy0.0156759784556345
GO:0016241regulation of macroautophagy0.0156759784556345
GO:0033344cholesterol efflux0.0156759784556345
GO:0008158hedgehog receptor activity0.0156759784556345
GO:0007041lysosomal transport0.0156759784556345
GO:0008206bile acid metabolic process0.0156759784556345
GO:0016236macroautophagy0.0156759784556345
GO:0030301cholesterol transport0.0156759784556345
GO:0015918sterol transport0.0156759784556345
GO:0007034vacuolar transport0.0156759784556345
GO:0042632cholesterol homeostasis0.0156759784556345
GO:0055088lipid homeostasis0.0156759784556345
GO:0055092sterol homeostasis0.0156759784556345
GO:0006914autophagy0.0196872959981344



Relative expression of the co-expression cluster over median <br>Analyst:


"{{{coexpression_dpi_cluster_scores_median}}}" is not a number.

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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