MCL coexpression mm9:110: Difference between revisions
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{{MCL_coexpression_mm9 | {{MCL_coexpression_mm9 | ||
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|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0570741246689917,0,0,0,0,0,0,0,0,0,0,0.196153902644494,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.456960520238567,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.1587130573671,0,0,0.0445418537893845,0.0824580172145032,0.24573158740015,0.439843518889665,0.423748563837555,1.30045302167962,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0 | |||
|gostat_on_MCL_coexpression=GO:0006811;ion transport;0.000701743850737937;209195,11944,20535,246133,110895,14603,16517!GO:0022857;transmembrane transporter activity;0.00113329059201128;209195,11944,20535,246133,110895,14603,16517!GO:0015075;ion transmembrane transporter activity;0.00176454111586569;209195,11944,20535,246133,14603,16517!GO:0030001;metal ion transport;0.00184956609549029;11944,246133,110895,14603,16517!GO:0022891;substrate-specific transmembrane transporter activity;0.00233612949469922;209195,11944,20535,246133,14603,16517!GO:0006812;cation transport;0.00251675989128272;11944,246133,110895,14603,16517!GO:0004198;calcium-dependent cysteine-type endopeptidase activity;0.00251675989128272;381122,23830!GO:0015672;monovalent inorganic cation transport;0.0040605216521477;11944,246133,110895,16517!GO:0030955;potassium ion binding;0.0040605216521477;11944,246133,16517!GO:0022892;substrate-specific transporter activity;0.00434126924543376;209195,11944,20535,246133,14603,16517!GO:0006813;potassium ion transport;0.00875827746623056;11944,246133,16517!GO:0022832;voltage-gated channel activity;0.00956458177064376;209195,246133,16517!GO:0005244;voltage-gated ion channel activity;0.00956458177064376;209195,246133,16517!GO:0015297;antiporter activity;0.00957760454201461;20535,110895!GO:0031420;alkali metal ion binding;0.00981471050896882;11944,246133,16517!GO:0003955;NAD(P)H dehydrogenase (quinone) activity;0.0116338651825163;18104!GO:0004276;furin activity;0.0116338651825163;18550!GO:0008324;cation transmembrane transporter activity;0.0116727456090333;11944,246133,14603,16517!GO:0008900;hydrogen:potassium-exchanging ATPase activity;0.0188264938632633;11944!GO:0043206;fibril organization and biogenesis;0.0188264938632633;17833!GO:0015889;cobalamin transport;0.0188264938632633;14603!GO:0022836;gated channel activity;0.0199736596085369;209195,246133,16517!GO:0046873;metal ion transmembrane transporter activity;0.0225434404746776;246133,14603,16517!GO:0015087;cobalt ion transmembrane transporter activity;0.0225434404746776;14603!GO:0006508;proteolysis;0.0225434404746776;18550,619326,381122,23830!GO:0016787;hydrolase activity;0.0225434404746776;11944,18550,619326,57319,70166,381122,23830!GO:0005249;voltage-gated potassium channel activity;0.0225434404746776;246133,16517!GO:0004197;cysteine-type endopeptidase activity;0.0225434404746776;381122,23830!GO:0022804;active transmembrane transporter activity;0.0246854152654115;11944,20535,110895!GO:0051180;vitamin transport;0.0246854152654115;14603!GO:0006824;cobalt ion transport;0.0246854152654115;14603!GO:0004090;carbonyl reductase (NADPH) activity;0.0246854152654115;109857!GO:0008233;peptidase activity;0.0249026394601886;18550,619326,381122,23830!GO:0043167;ion binding;0.0274147196029471;209195,11944,18550,619326,26359,16517,246133,381122,14603!GO:0005216;ion channel activity;0.0274147196029471;209195,246133,16517!GO:0031419;cobalamin binding;0.0274147196029471;14603!GO:0022838;substrate specific channel activity;0.0284210641330589;209195,246133,16517!GO:0006810;transport;0.0284210641330589;209195,11944,20535,246133,110895,14603,16517!GO:0008509;anion transmembrane transporter activity;0.0284210641330589;209195,20535!GO:0043205;fibril;0.0284210641330589;17833!GO:0022843;voltage-gated cation channel activity;0.0284210641330589;246133,16517!GO:0022803;passive transmembrane transporter activity;0.0284210641330589;209195,246133,16517!GO:0015267;channel activity;0.0284210641330589;209195,246133,16517!GO:0051234;establishment of localization;0.0287062868740622;209195,11944,20535,246133,110895,14603,16517!GO:0005267;potassium channel activity;0.0296987151777888;246133,16517!GO:0022890;inorganic cation transmembrane transporter activity;0.0328490534452536;11944,14603!GO:0012510;trans-Golgi network transport vesicle membrane;0.0328490534452536;18550!GO:0005452;inorganic anion exchanger activity;0.0328490534452536;20535!GO:0005887;integral to plasma membrane;0.0336443462931283;20535,57276,110895,16517!GO:0004175;endopeptidase activity;0.0336443462931283;18550,381122,23830!GO:0031226;intrinsic to plasma membrane;0.0341669082464488;20535,57276,110895,16517!GO:0043169;cation binding;0.0360019187842886;11944,246133,18550,619326,26359,14603,381122,16517!GO:0015380;anion exchanger activity;0.0366921226086729;20535!GO:0008234;cysteine-type peptidase activity;0.0366921226086729;381122,23830!GO:0015106;bicarbonate transmembrane transporter activity;0.0366921226086729;20535!GO:0030660;Golgi-associated vesicle membrane;0.0366921226086729;18550!GO:0030658;transport vesicle membrane;0.0366921226086729;18550!GO:0050897;cobalt ion binding;0.0366921226086729;14603!GO:0015301;anion:anion antiporter activity;0.0366921226086729;20535!GO:0015108;chloride transmembrane transporter activity;0.0386963182311876;20535!GO:0030140;trans-Golgi network transport vesicle;0.0386963182311876;18550!GO:0006820;anion transport;0.0387991725533378;209195,20535!GO:0051179;localization;0.0387991725533378;209195,11944,20535,246133,110895,14603,16517!GO:0015291;secondary active transmembrane transporter activity;0.0416844967010831;20535,110895!GO:0005242;inward rectifier potassium channel activity;0.0416844967010831;16517!GO:0004289;subtilase activity;0.0416844967010831;18550!GO:0005247;voltage-gated chloride channel activity;0.0426991062891871;209195!GO:0022844;voltage-gated anion channel activity;0.0426991062891871;209195!GO:0030665;clathrin coated vesicle membrane;0.0426991062891871;18550!GO:0046872;metal ion binding;0.0436751196297037;11944,246133,18550,619326,26359,14603,381122,16517!GO:0030133;transport vesicle;0.0497220931029031;18550! | |gostat_on_MCL_coexpression=GO:0006811;ion transport;0.000701743850737937;209195,11944,20535,246133,110895,14603,16517!GO:0022857;transmembrane transporter activity;0.00113329059201128;209195,11944,20535,246133,110895,14603,16517!GO:0015075;ion transmembrane transporter activity;0.00176454111586569;209195,11944,20535,246133,14603,16517!GO:0030001;metal ion transport;0.00184956609549029;11944,246133,110895,14603,16517!GO:0022891;substrate-specific transmembrane transporter activity;0.00233612949469922;209195,11944,20535,246133,14603,16517!GO:0006812;cation transport;0.00251675989128272;11944,246133,110895,14603,16517!GO:0004198;calcium-dependent cysteine-type endopeptidase activity;0.00251675989128272;381122,23830!GO:0015672;monovalent inorganic cation transport;0.0040605216521477;11944,246133,110895,16517!GO:0030955;potassium ion binding;0.0040605216521477;11944,246133,16517!GO:0022892;substrate-specific transporter activity;0.00434126924543376;209195,11944,20535,246133,14603,16517!GO:0006813;potassium ion transport;0.00875827746623056;11944,246133,16517!GO:0022832;voltage-gated channel activity;0.00956458177064376;209195,246133,16517!GO:0005244;voltage-gated ion channel activity;0.00956458177064376;209195,246133,16517!GO:0015297;antiporter activity;0.00957760454201461;20535,110895!GO:0031420;alkali metal ion binding;0.00981471050896882;11944,246133,16517!GO:0003955;NAD(P)H dehydrogenase (quinone) activity;0.0116338651825163;18104!GO:0004276;furin activity;0.0116338651825163;18550!GO:0008324;cation transmembrane transporter activity;0.0116727456090333;11944,246133,14603,16517!GO:0008900;hydrogen:potassium-exchanging ATPase activity;0.0188264938632633;11944!GO:0043206;fibril organization and biogenesis;0.0188264938632633;17833!GO:0015889;cobalamin transport;0.0188264938632633;14603!GO:0022836;gated channel activity;0.0199736596085369;209195,246133,16517!GO:0046873;metal ion transmembrane transporter activity;0.0225434404746776;246133,14603,16517!GO:0015087;cobalt ion transmembrane transporter activity;0.0225434404746776;14603!GO:0006508;proteolysis;0.0225434404746776;18550,619326,381122,23830!GO:0016787;hydrolase activity;0.0225434404746776;11944,18550,619326,57319,70166,381122,23830!GO:0005249;voltage-gated potassium channel activity;0.0225434404746776;246133,16517!GO:0004197;cysteine-type endopeptidase activity;0.0225434404746776;381122,23830!GO:0022804;active transmembrane transporter activity;0.0246854152654115;11944,20535,110895!GO:0051180;vitamin transport;0.0246854152654115;14603!GO:0006824;cobalt ion transport;0.0246854152654115;14603!GO:0004090;carbonyl reductase (NADPH) activity;0.0246854152654115;109857!GO:0008233;peptidase activity;0.0249026394601886;18550,619326,381122,23830!GO:0043167;ion binding;0.0274147196029471;209195,11944,18550,619326,26359,16517,246133,381122,14603!GO:0005216;ion channel activity;0.0274147196029471;209195,246133,16517!GO:0031419;cobalamin binding;0.0274147196029471;14603!GO:0022838;substrate specific channel activity;0.0284210641330589;209195,246133,16517!GO:0006810;transport;0.0284210641330589;209195,11944,20535,246133,110895,14603,16517!GO:0008509;anion transmembrane transporter activity;0.0284210641330589;209195,20535!GO:0043205;fibril;0.0284210641330589;17833!GO:0022843;voltage-gated cation channel activity;0.0284210641330589;246133,16517!GO:0022803;passive transmembrane transporter activity;0.0284210641330589;209195,246133,16517!GO:0015267;channel activity;0.0284210641330589;209195,246133,16517!GO:0051234;establishment of localization;0.0287062868740622;209195,11944,20535,246133,110895,14603,16517!GO:0005267;potassium channel activity;0.0296987151777888;246133,16517!GO:0022890;inorganic cation transmembrane transporter activity;0.0328490534452536;11944,14603!GO:0012510;trans-Golgi network transport vesicle membrane;0.0328490534452536;18550!GO:0005452;inorganic anion exchanger activity;0.0328490534452536;20535!GO:0005887;integral to plasma membrane;0.0336443462931283;20535,57276,110895,16517!GO:0004175;endopeptidase activity;0.0336443462931283;18550,381122,23830!GO:0031226;intrinsic to plasma membrane;0.0341669082464488;20535,57276,110895,16517!GO:0043169;cation binding;0.0360019187842886;11944,246133,18550,619326,26359,14603,381122,16517!GO:0015380;anion exchanger activity;0.0366921226086729;20535!GO:0008234;cysteine-type peptidase activity;0.0366921226086729;381122,23830!GO:0015106;bicarbonate transmembrane transporter activity;0.0366921226086729;20535!GO:0030660;Golgi-associated vesicle membrane;0.0366921226086729;18550!GO:0030658;transport vesicle membrane;0.0366921226086729;18550!GO:0050897;cobalt ion binding;0.0366921226086729;14603!GO:0015301;anion:anion antiporter activity;0.0366921226086729;20535!GO:0015108;chloride transmembrane transporter activity;0.0386963182311876;20535!GO:0030140;trans-Golgi network transport vesicle;0.0386963182311876;18550!GO:0006820;anion transport;0.0387991725533378;209195,20535!GO:0051179;localization;0.0387991725533378;209195,11944,20535,246133,110895,14603,16517!GO:0015291;secondary active transmembrane transporter activity;0.0416844967010831;20535,110895!GO:0005242;inward rectifier potassium channel activity;0.0416844967010831;16517!GO:0004289;subtilase activity;0.0416844967010831;18550!GO:0005247;voltage-gated chloride channel activity;0.0426991062891871;209195!GO:0022844;voltage-gated anion channel activity;0.0426991062891871;209195!GO:0030665;clathrin coated vesicle membrane;0.0426991062891871;18550!GO:0046872;metal ion binding;0.0436751196297037;11944,246133,18550,619326,26359,14603,381122,16517!GO:0030133;transport vesicle;0.0497220931029031;18550! | ||
}} | }} |
Revision as of 12:36, 11 October 2012
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0006811 | ion transport | 0.000701743850737937 |
GO:0022857 | transmembrane transporter activity | 0.00113329059201128 |
GO:0015075 | ion transmembrane transporter activity | 0.00176454111586569 |
GO:0030001 | metal ion transport | 0.00184956609549029 |
GO:0022891 | substrate-specific transmembrane transporter activity | 0.00233612949469922 |
GO:0006812 | cation transport | 0.00251675989128272 |
GO:0004198 | calcium-dependent cysteine-type endopeptidase activity | 0.00251675989128272 |
GO:0015672 | monovalent inorganic cation transport | 0.0040605216521477 |
GO:0030955 | potassium ion binding | 0.0040605216521477 |
GO:0022892 | substrate-specific transporter activity | 0.00434126924543376 |
GO:0006813 | potassium ion transport | 0.00875827746623056 |
GO:0022832 | voltage-gated channel activity | 0.00956458177064376 |
GO:0005244 | voltage-gated ion channel activity | 0.00956458177064376 |
GO:0015297 | antiporter activity | 0.00957760454201461 |
GO:0031420 | alkali metal ion binding | 0.00981471050896882 |
GO:0003955 | NAD(P)H dehydrogenase (quinone) activity | 0.0116338651825163 |
GO:0004276 | furin activity | 0.0116338651825163 |
GO:0008324 | cation transmembrane transporter activity | 0.0116727456090333 |
GO:0008900 | hydrogen:potassium-exchanging ATPase activity | 0.0188264938632633 |
GO:0043206 | fibril organization and biogenesis | 0.0188264938632633 |
GO:0015889 | cobalamin transport | 0.0188264938632633 |
GO:0022836 | gated channel activity | 0.0199736596085369 |
GO:0046873 | metal ion transmembrane transporter activity | 0.0225434404746776 |
GO:0015087 | cobalt ion transmembrane transporter activity | 0.0225434404746776 |
GO:0006508 | proteolysis | 0.0225434404746776 |
GO:0016787 | hydrolase activity | 0.0225434404746776 |
GO:0005249 | voltage-gated potassium channel activity | 0.0225434404746776 |
GO:0004197 | cysteine-type endopeptidase activity | 0.0225434404746776 |
GO:0022804 | active transmembrane transporter activity | 0.0246854152654115 |
GO:0051180 | vitamin transport | 0.0246854152654115 |
GO:0006824 | cobalt ion transport | 0.0246854152654115 |
GO:0004090 | carbonyl reductase (NADPH) activity | 0.0246854152654115 |
GO:0008233 | peptidase activity | 0.0249026394601886 |
GO:0043167 | ion binding | 0.0274147196029471 |
GO:0005216 | ion channel activity | 0.0274147196029471 |
GO:0031419 | cobalamin binding | 0.0274147196029471 |
GO:0022838 | substrate specific channel activity | 0.0284210641330589 |
GO:0006810 | transport | 0.0284210641330589 |
GO:0008509 | anion transmembrane transporter activity | 0.0284210641330589 |
GO:0043205 | fibril | 0.0284210641330589 |
GO:0022843 | voltage-gated cation channel activity | 0.0284210641330589 |
GO:0022803 | passive transmembrane transporter activity | 0.0284210641330589 |
GO:0015267 | channel activity | 0.0284210641330589 |
GO:0051234 | establishment of localization | 0.0287062868740622 |
GO:0005267 | potassium channel activity | 0.0296987151777888 |
GO:0022890 | inorganic cation transmembrane transporter activity | 0.0328490534452536 |
GO:0012510 | trans-Golgi network transport vesicle membrane | 0.0328490534452536 |
GO:0005452 | inorganic anion exchanger activity | 0.0328490534452536 |
GO:0005887 | integral to plasma membrane | 0.0336443462931283 |
GO:0004175 | endopeptidase activity | 0.0336443462931283 |
GO:0031226 | intrinsic to plasma membrane | 0.0341669082464488 |
GO:0043169 | cation binding | 0.0360019187842886 |
GO:0015380 | anion exchanger activity | 0.0366921226086729 |
GO:0008234 | cysteine-type peptidase activity | 0.0366921226086729 |
GO:0015106 | bicarbonate transmembrane transporter activity | 0.0366921226086729 |
GO:0030660 | Golgi-associated vesicle membrane | 0.0366921226086729 |
GO:0030658 | transport vesicle membrane | 0.0366921226086729 |
GO:0050897 | cobalt ion binding | 0.0366921226086729 |
GO:0015301 | anion:anion antiporter activity | 0.0366921226086729 |
GO:0015108 | chloride transmembrane transporter activity | 0.0386963182311876 |
GO:0030140 | trans-Golgi network transport vesicle | 0.0386963182311876 |
GO:0006820 | anion transport | 0.0387991725533378 |
GO:0051179 | localization | 0.0387991725533378 |
GO:0015291 | secondary active transmembrane transporter activity | 0.0416844967010831 |
GO:0005242 | inward rectifier potassium channel activity | 0.0416844967010831 |
GO:0004289 | subtilase activity | 0.0416844967010831 |
GO:0005247 | voltage-gated chloride channel activity | 0.0426991062891871 |
GO:0022844 | voltage-gated anion channel activity | 0.0426991062891871 |
GO:0030665 | clathrin coated vesicle membrane | 0.0426991062891871 |
GO:0046872 | metal ion binding | 0.0436751196297037 |
GO:0030133 | transport vesicle | 0.0497220931029031 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
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Ontology term | p-value | n |
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Ontology term | p-value | n |
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TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
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{{{tfbs_overrepresentation_jaspar}}} |