MCL coexpression mm9:601

Phase1 CAGE Peaks

	Short description
Mm9::chr11:23795175..23795189,-	p2@Papolg
Mm9::chr15:5187479..5187496,+	p@chr15:5187479..5187496 +
Mm9::chr16:49856460..49856493,-	p@chr16:49856460..49856493 -
Mm9::chr16:49856709..49856732,+	p@chr16:49856709..49856732 +
Mm9::chr17:29629982..29630050,+	p3@Pim1
Mm9::chr17:29630059..29630073,+	p8@Pim1
Mm9::chr17:29630077..29630088,+	p9@Pim1
Mm9::chr17:29630114..29630128,+	p@chr17:29630114..29630128 +
Mm9::chr1:108610492..108610501,-	p4@Bcl2
Mm9::chr3:58902298..58902304,-	p@chr3:58902298..58902304 -
Mm9::chr6:129185107..129185119,+	p@chr6:129185107..129185119 +
Mm9::chr7:31941253..31941263,-	p@chr7:31941253..31941263 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0045069	regulation of viral genome replication	0.0119145437698286
GO:0050792	regulation of viral reproduction	0.0119145437698286
GO:0019079	viral genome replication	0.0119145437698286
GO:0046902	regulation of mitochondrial membrane permeability	0.0119145437698286
GO:0019058	viral infectious cycle	0.0119145437698286
GO:0051881	regulation of mitochondrial membrane potential	0.0119145437698286
GO:0004652	polynucleotide adenylyltransferase activity	0.0136158753894981
GO:0022415	viral reproductive process	0.0148915477320502
GO:0016032	viral reproduction	0.0158834472390889
GO:0001836	release of cytochrome c from mitochondria	0.0238186440108132
GO:0043631	RNA polyadenylation	0.0238186440108132
GO:0007006	mitochondrial membrane organization and biogenesis	0.0256466306647956
GO:0031069	hair follicle morphogenesis	0.0256466306647956
GO:0031123	RNA 3'-end processing	0.0289131305174863
GO:0008637	apoptotic mitochondrial changes	0.0301570578102471
GO:0006839	mitochondrial transport	0.0322040377729354
GO:0043524	negative regulation of neuron apoptosis	0.0322040377729354
GO:0043523	regulation of neuron apoptosis	0.0408962687220554
GO:0051402	neuron apoptosis	0.0408962687220554
GO:0022404	molting cycle process	0.0408962687220554
GO:0001942	hair follicle development	0.0408962687220554
GO:0022405	hair cycle process	0.0408962687220554
GO:0042391	regulation of membrane potential	0.0408962687220554
GO:0042633	hair cycle	0.0408962687220554
GO:0042303	molting cycle	0.0408962687220554
GO:0008632	apoptotic program	0.0421101746110773
GO:0048730	epidermis morphogenesis	0.0421101746110773
GO:0016772	transferase activity, transferring phosphorus-containing groups	0.0421101746110773
GO:0046982	protein heterodimerization activity	0.0483232202533136
GO:0005634	nucleus	0.0483232202533136

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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