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MCL coexpression mm9:2403: Difference between revisions

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{{MCL_coexpression_mm9
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0004921;interleukin-11 receptor activity;0.0190643145563095;16157!GO:0019970;interleukin-11 binding;0.0190643145563095;16157!GO:0001779;natural killer cell differentiation;0.0254163007270631;16157!GO:0045197;establishment and/or maintenance of epithelial cell polarity;0.0333534115511529;16202!GO:0035088;establishment and/or maintenance of apical/basal cell polarity;0.0381035655591249;16202!GO:0030101;natural killer cell activation;0.0381035655591249;16157!GO:0004198;calcium-dependent cysteine-type endopeptidase activity;0.0381035655591249;12336!GO:0001658;ureteric bud branching;0.0428571151686477;16202!GO:0007163;establishment and/or maintenance of cell polarity;0.0456691731015961;16202!GO:0005925;focal adhesion;0.0456691731015961;16202!GO:0005924;cell-substrate adherens junction;0.0456691731015961;16202!GO:0001657;ureteric bud development;0.0456691731015961;16202!GO:0004907;interleukin receptor activity;0.0456691731015961;16157!GO:0030055;cell-matrix junction;0.0456691731015961;16202!GO:0019965;interleukin binding;0.0456691731015961;16157!
|gostat_on_MCL_coexpression=GO:0004921;interleukin-11 receptor activity;0.0190643145563095;16157!GO:0019970;interleukin-11 binding;0.0190643145563095;16157!GO:0001779;natural killer cell differentiation;0.0254163007270631;16157!GO:0045197;establishment and/or maintenance of epithelial cell polarity;0.0333534115511529;16202!GO:0035088;establishment and/or maintenance of apical/basal cell polarity;0.0381035655591249;16202!GO:0030101;natural killer cell activation;0.0381035655591249;16157!GO:0004198;calcium-dependent cysteine-type endopeptidase activity;0.0381035655591249;12336!GO:0001658;ureteric bud branching;0.0428571151686477;16202!GO:0007163;establishment and/or maintenance of cell polarity;0.0456691731015961;16202!GO:0005925;focal adhesion;0.0456691731015961;16202!GO:0005924;cell-substrate adherens junction;0.0456691731015961;16202!GO:0001657;ureteric bud development;0.0456691731015961;16202!GO:0004907;interleukin receptor activity;0.0456691731015961;16157!GO:0030055;cell-matrix junction;0.0456691731015961;16202!GO:0019965;interleukin binding;0.0456691731015961;16157!
}}
}}

Revision as of 13:12, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr4:41707334..41707363,+p1@Il11ra1
Mm9::chr7:112885158..112885212,+p1@Ilk
Mm9::chr7:30980039..30980050,-p2@Capns1
Mm9::chr7:30980065..30980109,-p1@Capns1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0004921interleukin-11 receptor activity0.0190643145563095
GO:0019970interleukin-11 binding0.0190643145563095
GO:0001779natural killer cell differentiation0.0254163007270631
GO:0045197establishment and/or maintenance of epithelial cell polarity0.0333534115511529
GO:0035088establishment and/or maintenance of apical/basal cell polarity0.0381035655591249
GO:0030101natural killer cell activation0.0381035655591249
GO:0004198calcium-dependent cysteine-type endopeptidase activity0.0381035655591249
GO:0001658ureteric bud branching0.0428571151686477
GO:0007163establishment and/or maintenance of cell polarity0.0456691731015961
GO:0005925focal adhesion0.0456691731015961
GO:0005924cell-substrate adherens junction0.0456691731015961
GO:0001657ureteric bud development0.0456691731015961
GO:0004907interleukin receptor activity0.0456691731015961
GO:0030055cell-matrix junction0.0456691731015961
GO:0019965interleukin binding0.0456691731015961



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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