MCL coexpression mm9:1314

Phase1 CAGE Peaks

	Short description
Mm9::chr11:97548520..97548544,-	p@chr11:97548520..97548544 -
Mm9::chr15:99548009..99548025,+	p1@Gpd1
Mm9::chr2:30270822..30270888,-	p3@Crat
Mm9::chr2:30270909..30270930,-	p7@Crat
Mm9::chr2:30270938..30270949,-	p8@Crat
Mm9::chr9:55258366..55258370,-	p@chr9:55258366..55258370 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0047936	glucose 1-dehydrogenase activity	0.00427327014737304
GO:0004092	carnitine O-acetyltransferase activity	0.00427327014737304
GO:0017057	6-phosphogluconolactonase activity	0.00569753744574322
GO:0004345	glucose-6-phosphate dehydrogenase activity	0.00640955403186268
GO:0016413	O-acetyltransferase activity	0.00683667033308187
GO:0016406	carnitine O-acyltransferase activity	0.00854490141182739
GO:0006098	pentose-phosphate shunt	0.00854490141182739
GO:0006740	NADPH regeneration	0.00854490141182739
GO:0005783	endoplasmic reticulum	0.0119405887772731
GO:0006739	NADP metabolic process	0.0119608953170559
GO:0006769	nicotinamide metabolic process	0.0170823107874551
GO:0019362	pyridine nucleotide metabolic process	0.0170823107874551
GO:0008374	O-acyltransferase activity	0.0195183597364061
GO:0006733	oxidoreduction coenzyme metabolic process	0.0195183597364061
GO:0006767	water-soluble vitamin metabolic process	0.0221978731045733
GO:0006007	glucose catabolic process	0.0243202733094806
GO:0046365	monosaccharide catabolic process	0.0243202733094806
GO:0019320	hexose catabolic process	0.0243202733094806
GO:0046164	alcohol catabolic process	0.0243202733094806
GO:0016407	acetyltransferase activity	0.0243202733094806
GO:0006766	vitamin metabolic process	0.0251904777736148
GO:0044275	cellular carbohydrate catabolic process	0.0255939662886466
GO:0016052	carbohydrate catabolic process	0.0267023499321227
GO:0042579	microbody	0.0300121230510755
GO:0005777	peroxisome	0.0300121230510755
GO:0006006	glucose metabolic process	0.0318013163867797
GO:0004091	carboxylesterase activity	0.0328271196865096
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.0334754378610183
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	0.0349569205496525
GO:0019318	hexose metabolic process	0.0368085097930655
GO:0005996	monosaccharide metabolic process	0.0368085097930655
GO:0005792	microsome	0.0388997222394472
GO:0042598	vesicular fraction	0.0388997222394472
GO:0006732	coenzyme metabolic process	0.0388997222394472
GO:0006631	fatty acid metabolic process	0.0388997222394472
GO:0008415	acyltransferase activity	0.0393149282099043
GO:0016747	transferase activity, transferring groups other than amino-acyl groups	0.0393149282099043
GO:0016746	transferase activity, transferring acyl groups	0.0394691272818788
GO:0009117	nucleotide metabolic process	0.0394691272818788
GO:0051186	cofactor metabolic process	0.039751491500519
GO:0055086	nucleobase, nucleoside and nucleotide metabolic process	0.0402259186969485
GO:0032787	monocarboxylic acid metabolic process	0.0430914495999688
GO:0044265	cellular macromolecule catabolic process	0.0444458513791493
GO:0044262	cellular carbohydrate metabolic process	0.0475800590742983
GO:0006066	alcohol metabolic process	0.0475800590742983
GO:0044444	cytoplasmic part	0.0475800590742983

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
intestine	6.04e-10	31
mucosa	2.96e-08	15
intestinal mucosa	3.96e-07	13
anatomical wall	3.96e-07	13
wall of intestine	3.96e-07	13
gastrointestinal system mucosa	3.96e-07	13

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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