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MCL coexpression mm9:1358: Difference between revisions

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|gostat_on_MCL_coexpression=GO:0008475;procollagen-lysine 5-dioxygenase activity;0.0207066553792883;26433!GO:0030307;positive regulation of cell growth;0.0207066553792883;12520!GO:0045793;positive regulation of cell size;0.0230048737377879;12520!GO:0030890;positive regulation of B cell proliferation;0.037222988647217;12520!GO:0031418;L-ascorbic acid binding;0.037222988647217;26433!GO:0030888;regulation of B cell proliferation;0.037222988647217;12520!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.037222988647217;26433!GO:0050871;positive regulation of B cell activation;0.037222988647217;12520!GO:0045927;positive regulation of growth;0.037222988647217;12520!GO:0042100;B cell proliferation;0.037222988647217;12520!GO:0032946;positive regulation of mononuclear cell proliferation;0.0392164037242194;12520!GO:0050671;positive regulation of lymphocyte proliferation;0.0392164037242194;12520!GO:0050864;regulation of B cell activation;0.0392164037242194;12520!GO:0032944;regulation of mononuclear cell proliferation;0.0441788138872621;12520!GO:0050670;regulation of lymphocyte proliferation;0.0441788138872621;12520!GO:0051213;dioxygenase activity;0.0441788138872621;26433!GO:0016702;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;0.0441788138872621;26433!GO:0016701;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;0.0441788138872621;26433!GO:0051251;positive regulation of lymphocyte activation;0.0441788138872621;12520!GO:0032943;mononuclear cell proliferation;0.0472716327546309;12520!GO:0046651;lymphocyte proliferation;0.0472716327546309;12520!GO:0001558;regulation of cell growth;0.0472716327546309;12520!GO:0051249;regulation of lymphocyte activation;0.0472716327546309;12520!GO:0042113;B cell activation;0.0472716327546309;12520!GO:0050865;regulation of cell activation;0.0472716327546309;12520!GO:0016049;cell growth;0.0496599180348516;12520!
|gostat_on_MCL_coexpression=GO:0008475;procollagen-lysine 5-dioxygenase activity;0.0207066553792883;26433!GO:0030307;positive regulation of cell growth;0.0207066553792883;12520!GO:0045793;positive regulation of cell size;0.0230048737377879;12520!GO:0030890;positive regulation of B cell proliferation;0.037222988647217;12520!GO:0031418;L-ascorbic acid binding;0.037222988647217;26433!GO:0030888;regulation of B cell proliferation;0.037222988647217;12520!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.037222988647217;26433!GO:0050871;positive regulation of B cell activation;0.037222988647217;12520!GO:0045927;positive regulation of growth;0.037222988647217;12520!GO:0042100;B cell proliferation;0.037222988647217;12520!GO:0032946;positive regulation of mononuclear cell proliferation;0.0392164037242194;12520!GO:0050671;positive regulation of lymphocyte proliferation;0.0392164037242194;12520!GO:0050864;regulation of B cell activation;0.0392164037242194;12520!GO:0032944;regulation of mononuclear cell proliferation;0.0441788138872621;12520!GO:0050670;regulation of lymphocyte proliferation;0.0441788138872621;12520!GO:0051213;dioxygenase activity;0.0441788138872621;26433!GO:0016702;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;0.0441788138872621;26433!GO:0016701;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;0.0441788138872621;26433!GO:0051251;positive regulation of lymphocyte activation;0.0441788138872621;12520!GO:0032943;mononuclear cell proliferation;0.0472716327546309;12520!GO:0046651;lymphocyte proliferation;0.0472716327546309;12520!GO:0001558;regulation of cell growth;0.0472716327546309;12520!GO:0051249;regulation of lymphocyte activation;0.0472716327546309;12520!GO:0042113;B cell activation;0.0472716327546309;12520!GO:0050865;regulation of cell activation;0.0472716327546309;12520!GO:0016049;cell growth;0.0496599180348516;12520!
|ontology_enrichment_celltype=CL:0000055!3.25e-07!49;CL:0002453!6.68e-07!8
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000025!4.86e-15!114;UBERON:0004111!1.97e-14!122;UBERON:0001017!9.91e-09!73;UBERON:0001016!1.49e-08!75;UBERON:0010314!3.36e-08!92;UBERON:0004535!3.32e-07!23;UBERON:0001009!3.32e-07!23;UBERON:0003914!3.93e-07!47
}}
}}

Revision as of 16:45, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr14:26588519..26588569,-p1@Zcchc24
Mm9::chr15:78004386..78004418,-p2@Ift27
Mm9::chr5:116102983..116103001,-p1@Ccdc64
Mm9::chr5:137463227..137463253,+p3@Plod3
Mm9::chr5:34000486..34000536,-p2@Tmem129
Mm9::chr7:150238681..150238702,+p1@Cd81


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0008475procollagen-lysine 5-dioxygenase activity0.0207066553792883
GO:0030307positive regulation of cell growth0.0207066553792883
GO:0045793positive regulation of cell size0.0230048737377879
GO:0030890positive regulation of B cell proliferation0.037222988647217
GO:0031418L-ascorbic acid binding0.037222988647217
GO:0030888regulation of B cell proliferation0.037222988647217
GO:0016706oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors0.037222988647217
GO:0050871positive regulation of B cell activation0.037222988647217
GO:0045927positive regulation of growth0.037222988647217
GO:0042100B cell proliferation0.037222988647217
GO:0032946positive regulation of mononuclear cell proliferation0.0392164037242194
GO:0050671positive regulation of lymphocyte proliferation0.0392164037242194
GO:0050864regulation of B cell activation0.0392164037242194
GO:0032944regulation of mononuclear cell proliferation0.0441788138872621
GO:0050670regulation of lymphocyte proliferation0.0441788138872621
GO:0051213dioxygenase activity0.0441788138872621
GO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen0.0441788138872621
GO:0016701oxidoreductase activity, acting on single donors with incorporation of molecular oxygen0.0441788138872621
GO:0051251positive regulation of lymphocyte activation0.0441788138872621
GO:0032943mononuclear cell proliferation0.0472716327546309
GO:0046651lymphocyte proliferation0.0472716327546309
GO:0001558regulation of cell growth0.0472716327546309
GO:0051249regulation of lymphocyte activation0.0472716327546309
GO:0042113B cell activation0.0472716327546309
GO:0050865regulation of cell activation0.0472716327546309
GO:0016049cell growth0.0496599180348516



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
non-terminally differentiated cell3.25e-0749
oligodendrocyte precursor cell6.68e-078

Uber Anatomy
Ontology termp-valuen
tube4.86e-15114
anatomical conduit1.97e-14122
central nervous system9.91e-0973
nervous system1.49e-0875
structure with developmental contribution from neural crest3.36e-0892
cardiovascular system3.32e-0723
circulatory system3.32e-0723
epithelial tube3.93e-0747


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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