MCL coexpression mm9:754

Phase1 CAGE Peaks

	Short description
Mm9::chr10:126485291..126485302,+	p1@Cyp27b1
Mm9::chr13:25166617..25166625,+	p@chr13:25166617..25166625 +
Mm9::chr18:52959880..52959889,+	p@chr18:52959880..52959889 +
Mm9::chr19:44042981..44042999,-	p11@Cpn1
Mm9::chr6:65729630..65729636,-	p1@ENSMUST00000144594
Mm9::chr6:65729683..65729688,-	p4@ENSMUST00000144594
Mm9::chr6:65729691..65729700,-	p2@ENSMUST00000144594
Mm9::chr6:65729708..65729717,-	p3@ENSMUST00000144594
Mm9::chr6:65729767..65729772,-	p@chr6:65729767..65729772 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004184	lysine carboxypeptidase activity	0.00279406125020545
GO:0004498	calcidiol 1-monooxygenase activity	0.00279406125020545
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen	0.0335020986526113
GO:0004182	carboxypeptidase A activity	0.0335020986526113
GO:0004181	metallocarboxypeptidase activity	0.0335020986526113
GO:0004180	carboxypeptidase activity	0.0390729228338641
GO:0008235	metalloexopeptidase activity	0.0438417260836336

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
kidney	1.38e-43	14
kidney mesenchyme	1.38e-43	14
upper urinary tract	1.38e-43	14
kidney rudiment	1.38e-43	14
kidney field	1.38e-43	14
urinary system structure	5.27e-34	18
renal system	3.08e-32	19
cavitated compound organ	3.30e-29	21
compound organ	2.01e-14	43
abdomen element	1.11e-12	49
abdominal segment element	1.11e-12	49
abdominal segment of trunk	1.11e-12	49
abdomen	1.11e-12	49
mesenchyme	3.20e-10	61
entire embryonic mesenchyme	3.20e-10	61
subdivision of trunk	1.86e-09	66
trunk region element	6.48e-08	79
trunk	5.94e-07	90

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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