Novel motif:32

name:	motif32_TRGNMCTNNT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0043589	skin morphogenesis	7.859515e-56
GO:0070208	protein heterotrimerization	8.679309e-51
GO:0032964	collagen biosynthetic process	4.073815e-49
GO:0070206	protein trimerization	6.095474e-40
GO:0034505	tooth mineralization	3.363551e-38
GO:0030199	collagen fibril organization	1.559417e-37
GO:0032963	collagen metabolic process	2.017287e-31
GO:0030198	extracellular matrix organization	1.058597e-30
GO:0001957	intramembranous ossification	1.417197e-30
GO:0044259	multicellular organismal macromolecule metabolic process	1.566640e-30
GO:0071230	cellular response to amino acid stimulus	2.015949e-30
GO:0001101	response to acid	1.774055e-29
GO:0071229	cellular response to acid	4.370718e-29
GO:0060346	bone trabecula formation	6.368469e-29
GO:0071418	cellular response to amine stimulus	2.030101e-28
GO:0044236	multicellular organismal metabolic process	2.144386e-28
GO:0071417	cellular response to organic nitrogen	4.442446e-28
GO:0060351	cartilage development involved in endochondral bone morphogenesis	2.124309e-27
GO:0043588	skin development	1.038354e-25
GO:0048730	epidermis morphogenesis	1.240667e-25
GO:0043200	response to amino acid stimulus	1.380638e-25
GO:0030277	maintenance of gastrointestinal epithelium	4.550694e-25
GO:0010669	epithelial structure maintenance	6.644554e-23
GO:0006342	chromatin silencing	2.908229e-21
GO:0060343	trabecula formation	1.987936e-20
GO:0061383	trabecula morphogenesis	2.078114e-20
GO:0001958	endochondral ossification	2.103658e-20
GO:0030261	chromosome condensation	2.728314e-20
GO:0051291	protein heterooligomerization	1.998957e-19
GO:0014075	response to amine stimulus	1.063307e-18
GO:0071300	cellular response to retinoic acid	8.601127e-18
GO:0045814	negative regulation of gene expression, epigenetic	8.899962e-18
GO:0042476	odontogenesis	1.251721e-17
GO:0007411	axon guidance	3.010795e-17
GO:0071299	cellular response to vitamin A	5.512945e-17
GO:0060350	endochondral bone morphogenesis	1.779722e-16
GO:0022600	digestive system process	2.368919e-16
GO:0030168	platelet activation	4.445268e-16
GO:0006935	chemotaxis	6.391694e-16
GO:0065008	regulation of biological quality	2.472404e-15
GO:0032989	cellular component morphogenesis	2.627762e-15
GO:0033189	response to vitamin A	7.418028e-15
GO:0009605	response to external stimulus	9.294273e-15
GO:0007409	axonogenesis	9.684998e-15
GO:0050690	regulation of defense response to virus by virus	1.401854e-14
GO:0031175	neuron projection development	1.534522e-14
GO:0032526	response to retinoic acid	3.693154e-14
GO:0071295	cellular response to vitamin	3.825137e-14
GO:0009612	response to mechanical stimulus	4.387189e-14
GO:0048812	neuron projection morphogenesis	7.831128e-14
GO:0031960	response to corticosteroid stimulus	1.625332e-13
GO:0010243	response to organic nitrogen	1.893231e-13
GO:0048858	cell projection morphogenesis	3.618416e-13
GO:0032990	cell part morphogenesis	3.686754e-13
GO:0010812	negative regulation of cell-substrate adhesion	4.265224e-13
GO:0048667	cell morphogenesis involved in neuron differentiation	5.050657e-13
GO:0033273	response to vitamin	5.799812e-13
GO:0048739	cardiac muscle fiber development	1.150563e-12
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	1.287713e-12
GO:0010718	positive regulation of epithelial to mesenchymal transition	1.596114e-12
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	1.730694e-12
GO:0040011	locomotion	4.339840e-12
GO:0042396	phosphagen biosynthetic process	5.777879e-12
GO:0031214	biomineral tissue development	7.449624e-12
GO:0031670	cellular response to nutrient	7.466187e-12
GO:0001775	cell activation	8.705226e-12
GO:0030030	cell projection organization	1.713943e-11
GO:0043206	fibril organization	2.507434e-11
GO:0007586	digestion	3.203423e-11
GO:0048666	neuron development	3.587483e-11
GO:0050896	response to stimulus	3.953051e-11
GO:0007599	hemostasis	4.828410e-11
GO:0034728	nucleosome organization	6.770528e-11
GO:0003008	system process	8.650338e-11
GO:0050878	regulation of body fluid levels	9.761184e-11
GO:0000902	cell morphogenesis	1.119307e-10
GO:0030048	actin filament-based movement	1.208377e-10
GO:0048468	cell development	1.480479e-10
GO:0007596	blood coagulation	2.486993e-10
GO:0046314	phosphocreatine biosynthetic process	2.536907e-10
GO:0000904	cell morphogenesis involved in differentiation	2.599447e-10
GO:0050900	leukocyte migration	3.964504e-10
GO:0008544	epidermis development	5.570894e-10
GO:0006333	chromatin assembly or disassembly	7.012027e-10
GO:0006323	DNA packaging	1.058680e-9
GO:0006941	striated muscle contraction	1.167718e-9
GO:0000302	response to reactive oxygen species	1.452392e-9
GO:0007584	response to nutrient	1.690497e-9
GO:0071732	cellular response to nitric oxide	1.804424e-9
GO:0001894	tissue homeostasis	1.940467e-9
GO:0015889	cobalamin transport	1.965794e-9
GO:0002697	regulation of immune effector process	2.759308e-9
GO:0071103	DNA conformation change	3.343138e-9
GO:0072358	cardiovascular system development	3.393357e-9
GO:0010035	response to inorganic substance	3.511718e-9
GO:0006928	cellular component movement	5.584531e-9
GO:0030177	positive regulation of Wnt receptor signaling pathway	5.688573e-9
GO:0034621	cellular macromolecular complex subunit organization	7.004667e-9
GO:0051591	response to cAMP	7.022189e-9
GO:0055008	cardiac muscle tissue morphogenesis	1.009341e-8
GO:0006334	nucleosome assembly	1.471641e-8
GO:0032496	response to lipopolysaccharide	1.634506e-8
GO:0006461	protein complex assembly	2.174907e-8
GO:0001880	Mullerian duct regression	2.358011e-8
GO:0070271	protein complex biogenesis	2.538126e-8
GO:0060349	bone morphogenesis	2.673293e-8
GO:0030239	myofibril assembly	2.679425e-8
GO:0030241	skeletal muscle myosin thick filament assembly	3.196235e-8
GO:0007015	actin filament organization	3.196516e-8
GO:0034622	cellular macromolecular complex assembly	3.235189e-8
GO:0071822	protein complex subunit organization	3.429653e-8
GO:0006600	creatine metabolic process	3.568735e-8
GO:0050688	regulation of defense response to virus	5.523907e-8
GO:0007179	transforming growth factor beta receptor signaling pathway	5.967953e-8
GO:0042359	vitamin D metabolic process	6.479221e-8
GO:0006338	chromatin remodeling	7.901038e-8
GO:0031497	chromatin assembly	8.465838e-8
GO:0071731	response to nitric oxide	8.930594e-8
GO:0001546	preantral ovarian follicle growth	9.180654e-8
GO:0070252	actin-mediated cell contraction	9.537376e-8
GO:0030182	neuron differentiation	9.639221e-8
GO:0016032	viral reproduction	9.895055e-8
GO:0030049	muscle filament sliding	1.050176e-7
GO:0002237	response to molecule of bacterial origin	1.155143e-7
GO:0045214	sarcomere organization	1.158074e-7
GO:0048869	cellular developmental process	1.167596e-7
GO:0009611	response to wounding	1.188147e-7
GO:0071824	protein-DNA complex subunit organization	1.234563e-7
GO:0010717	regulation of epithelial to mesenchymal transition	1.334914e-7
GO:0048738	cardiac muscle tissue development	1.401302e-7
GO:0043933	macromolecular complex subunit organization	1.458167e-7
GO:0048644	muscle organ morphogenesis	1.557332e-7
GO:0031032	actomyosin structure organization	3.062055e-7
GO:0030154	cell differentiation	3.458298e-7
GO:0042221	response to chemical stimulus	3.656815e-7
GO:0007155	cell adhesion	3.734611e-7
GO:0008015	blood circulation	3.884433e-7
GO:0060415	muscle tissue morphogenesis	3.944731e-7
GO:0051259	protein oligomerization	3.946700e-7
GO:0060348	bone development	3.991388e-7
GO:2000491	positive regulation of hepatic stellate cell activation	4.149221e-7
GO:0009628	response to abiotic stimulus	4.412009e-7
GO:0060325	face morphogenesis	4.611516e-7
GO:0043900	regulation of multi-organism process	5.405775e-7
GO:0000910	cytokinesis	5.426929e-7
GO:0032502	developmental process	6.929957e-7
GO:0045010	actin nucleation	7.318109e-7
GO:0016192	vesicle-mediated transport	7.897352e-7
GO:0051014	actin filament severing	7.913082e-7
GO:0009235	cobalamin metabolic process	8.127002e-7
GO:0009653	anatomical structure morphogenesis	8.235287e-7
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	8.462884e-7
GO:0007162	negative regulation of cell adhesion	8.999915e-7
GO:0002831	regulation of response to biotic stimulus	9.024402e-7
GO:0003013	circulatory system process	1.012928e-6
GO:0009617	response to bacterium	1.122694e-6
GO:0051234	establishment of localization	1.126946e-6
GO:0060323	head morphogenesis	1.140303e-6
GO:0007281	germ cell development	1.148325e-6
GO:0002576	platelet degranulation	1.335130e-6
GO:0042060	wound healing	1.357178e-6
GO:0071842	cellular component organization at cellular level	1.398248e-6
GO:0007266	Rho protein signal transduction	1.418640e-6
GO:0051179	localization	1.471797e-6
GO:0060033	anatomical structure regression	1.562788e-6
GO:0032501	multicellular organismal process	1.566188e-6
GO:0072678	T cell migration	1.617836e-6
GO:0010810	regulation of cell-substrate adhesion	1.780566e-6
GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway	1.855544e-6
GO:0048747	muscle fiber development	1.917247e-6
GO:0031667	response to nutrient levels	2.019579e-6
GO:0065004	protein-DNA complex assembly	2.096483e-6
GO:0051716	cellular response to stimulus	2.320205e-6
GO:0070358	actin polymerization-dependent cell motility	2.425354e-6
GO:0060324	face development	2.440443e-6
GO:0014866	skeletal myofibril assembly	2.539614e-6
GO:0008064	regulation of actin polymerization or depolymerization	2.660962e-6
GO:0055002	striated muscle cell development	2.938176e-6
GO:0030029	actin filament-based process	3.018302e-6
GO:0006810	transport	3.024606e-6
GO:0071841	cellular component organization or biogenesis at cellular level	3.024943e-6
GO:0006936	muscle contraction	3.065011e-6
GO:0010171	body morphogenesis	3.269555e-6
GO:0048729	tissue morphogenesis	3.635137e-6
GO:0034109	homotypic cell-cell adhesion	3.650489e-6
GO:0002739	regulation of cytokine secretion involved in immune response	4.486499e-6
GO:0022008	neurogenesis	4.501803e-6
GO:0065003	macromolecular complex assembly	4.538079e-6
GO:0048856	anatomical structure development	4.588168e-6
GO:0071496	cellular response to external stimulus	5.162509e-6
GO:0001649	osteoblast differentiation	5.610586e-6
GO:0048871	multicellular organismal homeostasis	5.662337e-6
GO:0060426	lung vasculature development	5.815021e-6
GO:0060322	head development	6.415307e-6
GO:2000249	regulation of actin cytoskeleton reorganization	6.432211e-6
GO:0001944	vasculature development	7.757722e-6
GO:0051704	multi-organism process	7.962437e-6
GO:0006629	lipid metabolic process	8.070956e-6
GO:0055001	muscle cell development	8.334529e-6
GO:0051532	regulation of NFAT protein import into nucleus	9.734283e-6
GO:0043623	cellular protein complex assembly	9.751946e-6
GO:0007268	synaptic transmission	9.911084e-6
GO:0010506	regulation of autophagy	1.019272e-5
GO:0048699	generation of neurons	1.023999e-5
GO:0042542	response to hydrogen peroxide	1.025918e-5
GO:0002376	immune system process	1.034393e-5
GO:0017144	drug metabolic process	1.061978e-5
GO:0060828	regulation of canonical Wnt receptor signaling pathway	1.082018e-5
GO:0048545	response to steroid hormone stimulus	1.096767e-5
GO:0006026	aminoglycan catabolic process	1.135624e-5
GO:0048769	sarcomerogenesis	1.145993e-5
GO:0071460	cellular response to cell-matrix adhesion	1.217257e-5
GO:0030111	regulation of Wnt receptor signaling pathway	1.238444e-5
GO:0003214	cardiac left ventricle morphogenesis	1.271800e-5
GO:0034504	protein localization to nucleus	1.292314e-5
GO:0014002	astrocyte development	1.307290e-5
GO:0048613	embryonic ectodermal digestive tract morphogenesis	1.349869e-5
GO:0060461	right lung morphogenesis	1.349869e-5
GO:0090131	mesenchyme migration	1.349869e-5
GO:0060446	branching involved in open tracheal system development	1.349869e-5
GO:0002115	store-operated calcium entry	1.349869e-5
GO:0014822	detection of wounding	1.349869e-5
GO:0048371	lateral mesodermal cell differentiation	1.349869e-5
GO:2000279	negative regulation of DNA biosynthetic process	1.365294e-5
GO:0007605	sensory perception of sound	1.397329e-5
GO:0010927	cellular component assembly involved in morphogenesis	1.413680e-5
GO:0001568	blood vessel development	1.480797e-5
GO:0090288	negative regulation of cellular response to growth factor stimulus	1.487724e-5
GO:0003007	heart morphogenesis	1.624455e-5
GO:0016458	gene silencing	1.692820e-5
GO:0007154	cell communication	1.768529e-5
GO:0045198	establishment of epithelial cell apical/basal polarity	1.812510e-5
GO:0019254	carnitine metabolic process, CoA-linked	1.890374e-5
GO:0060048	cardiac muscle contraction	1.949212e-5
GO:0032274	gonadotropin secretion	1.949689e-5
GO:0002554	serotonin secretion by platelet	2.048245e-5
GO:0009991	response to extracellular stimulus	2.063495e-5
GO:0040029	regulation of gene expression, epigenetic	2.491937e-5
GO:0016477	cell migration	2.622504e-5
GO:0030335	positive regulation of cell migration	2.846668e-5
GO:0006887	exocytosis	3.053100e-5
GO:0016043	cellular component organization	3.119343e-5
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	3.123811e-5
GO:0060907	positive regulation of macrophage cytokine production	3.167728e-5
GO:0032800	receptor biosynthetic process	3.208276e-5
GO:0034337	RNA folding	3.212602e-5
GO:0071276	cellular response to cadmium ion	3.281190e-5
GO:0008211	glucocorticoid metabolic process	3.293271e-5
GO:0045920	negative regulation of exocytosis	3.344861e-5
GO:0006979	response to oxidative stress	3.422348e-5
GO:2000147	positive regulation of cell motility	3.536992e-5
GO:0015031	protein transport	3.885713e-5
GO:0051293	establishment of spindle localization	3.934864e-5
GO:0009887	organ morphogenesis	4.034531e-5
GO:0070489	T cell aggregation	4.217246e-5
GO:0003012	muscle system process	4.287038e-5
GO:0040017	positive regulation of locomotion	4.425089e-5
GO:0071840	cellular component organization or biogenesis	4.447200e-5
GO:0006700	C21-steroid hormone biosynthetic process	4.601110e-5
GO:0001501	skeletal system development	4.747917e-5
GO:0043301	negative regulation of leukocyte degranulation	4.828865e-5
GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway	5.110472e-5
GO:0044130	negative regulation of growth of symbiont in host	5.129588e-5
GO:0048870	cell motility	5.238042e-5
GO:0016095	polyprenol catabolic process	5.564308e-5
GO:0030801	positive regulation of cyclic nucleotide metabolic process	5.948554e-5
GO:0048731	system development	6.037957e-5
GO:0070060	'de novo' actin filament nucleation	6.041293e-5
GO:0016098	monoterpenoid metabolic process	6.068671e-5
GO:0007186	G-protein coupled receptor protein signaling pathway	6.096349e-5
GO:0030036	actin cytoskeleton organization	6.165977e-5
GO:0008104	protein localization	6.276372e-5
GO:0008217	regulation of blood pressure	6.353568e-5
GO:0045184	establishment of protein localization	6.378274e-5
GO:0002019	regulation of renal output by angiotensin	6.456021e-5
GO:0007522	visceral muscle development	6.843999e-5
GO:0090096	positive regulation of metanephric cap mesenchymal cell proliferation	7.024968e-5
GO:0050954	sensory perception of mechanical stimulus	7.469515e-5
GO:0051146	striated muscle cell differentiation	7.539982e-5
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	7.556721e-5
GO:0010720	positive regulation of cell development	7.673617e-5
GO:0031648	protein destabilization	7.952549e-5
GO:0002699	positive regulation of immune effector process	8.041395e-5
GO:0048706	embryonic skeletal system development	8.062843e-5
GO:0071495	cellular response to endogenous stimulus	8.123092e-5
GO:0070848	response to growth factor stimulus	8.357693e-5
GO:0043555	regulation of translation in response to stress	8.548991e-5
GO:0060249	anatomical structure homeostasis	9.397445e-5
GO:0007020	microtubule nucleation	9.440951e-5
GO:0000086	G2/M transition of mitotic cell cycle	9.564590e-5
GO:0007275	multicellular organismal development	9.612360e-5
GO:0007166	cell surface receptor linked signaling pathway	9.846438e-5
GO:0042559	pteridine-containing compound biosynthetic process	1.038526e-4
GO:0043060	meiotic metaphase I plate congression	1.042924e-4
GO:0002740	negative regulation of cytokine secretion involved in immune response	1.069046e-4
GO:0048609	multicellular organismal reproductive process	1.088240e-4
GO:0007283	spermatogenesis	1.101779e-4
GO:0000132	establishment of mitotic spindle orientation	1.137408e-4
GO:0055098	response to low-density lipoprotein particle stimulus	1.138247e-4
GO:0051641	cellular localization	1.138495e-4
GO:0034465	response to carbon monoxide	1.138919e-4
GO:0071363	cellular response to growth factor stimulus	1.157252e-4
GO:0002149	hypochlorous acid biosynthetic process	1.184591e-4
GO:0018283	iron incorporation into metallo-sulfur cluster	1.226027e-4
GO:0048841	regulation of axon extension involved in axon guidance	1.238415e-4
GO:0050715	positive regulation of cytokine secretion	1.257135e-4
GO:0031668	cellular response to extracellular stimulus	1.282577e-4
GO:0030832	regulation of actin filament length	1.288468e-4
GO:0051216	cartilage development	1.306732e-4
GO:0031669	cellular response to nutrient levels	1.316193e-4
GO:0030240	skeletal muscle thin filament assembly	1.319294e-4
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	1.328999e-4
GO:0044283	small molecule biosynthetic process	1.334672e-4
GO:0060047	heart contraction	1.339780e-4
GO:0032411	positive regulation of transporter activity	1.393732e-4
GO:0010950	positive regulation of endopeptidase activity	1.442364e-4
GO:0044029	hypomethylation of CpG island	1.442364e-4
GO:0042699	follicle-stimulating hormone signaling pathway	1.442364e-4
GO:0085018	maintenance of symbiont-containing vacuole via substance secreted by host	1.462378e-4
GO:0035378	carbon dioxide transmembrane transport	1.462378e-4
GO:0030950	establishment or maintenance of actin cytoskeleton polarity	1.462378e-4
GO:0035377	transepithelial water transport	1.462378e-4
GO:0010625	positive regulation of Schwann cell proliferation	1.650874e-4
GO:0006897	endocytosis	1.733889e-4
GO:0030819	positive regulation of cAMP biosynthetic process	1.761999e-4
GO:0019226	transmission of nerve impulse	1.805093e-4
GO:0048382	mesendoderm development	1.819015e-4
GO:0050707	regulation of cytokine secretion	1.911582e-4
GO:0051272	positive regulation of cellular component movement	1.915605e-4
GO:0048370	lateral mesoderm formation	1.932419e-4
GO:0071404	cellular response to low-density lipoprotein particle stimulus	2.026109e-4
GO:0007253	cytoplasmic sequestering of NF-kappaB	2.026109e-4
GO:0030816	positive regulation of cAMP metabolic process	2.033890e-4
GO:0048368	lateral mesoderm development	2.040600e-4
GO:0055003	cardiac myofibril assembly	2.056910e-4
GO:0006950	response to stress	2.091093e-4
GO:0050862	positive regulation of T cell receptor signaling pathway	2.134493e-4
GO:0030952	establishment or maintenance of cytoskeleton polarity	2.146933e-4
GO:0006270	DNA-dependent DNA replication initiation	2.218776e-4
GO:0016226	iron-sulfur cluster assembly	2.221425e-4
GO:0048352	paraxial mesoderm structural organization	2.278776e-4
GO:0021998	neural plate mediolateral regionalization	2.278776e-4
GO:0006692	prostanoid metabolic process	2.331298e-4
GO:0044057	regulation of system process	2.350943e-4
GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	2.351132e-4
GO:0040001	establishment of mitotic spindle localization	2.386479e-4
GO:0014896	muscle hypertrophy	2.433050e-4
GO:0022403	cell cycle phase	2.527225e-4
GO:0006259	DNA metabolic process	2.553313e-4
GO:0007010	cytoskeleton organization	2.567856e-4
GO:0018879	biphenyl metabolic process	2.685934e-4
GO:0031330	negative regulation of cellular catabolic process	2.701665e-4
GO:0008207	C21-steroid hormone metabolic process	2.730202e-4
GO:0007128	meiotic prophase I	2.756615e-4
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	2.756730e-4
GO:0018149	peptide cross-linking	2.867089e-4
GO:0007507	heart development	3.003825e-4
GO:0046626	regulation of insulin receptor signaling pathway	3.004200e-4
GO:0044419	interspecies interaction between organisms	3.166546e-4
GO:0006702	androgen biosynthetic process	3.424302e-4
GO:0019255	glucose 1-phosphate metabolic process	3.450120e-4
GO:0009988	cell-cell recognition	3.478767e-4
GO:0043534	blood vessel endothelial cell migration	3.608314e-4
GO:0048843	negative regulation of axon extension involved in axon guidance	3.697490e-4
GO:0071593	lymphocyte aggregation	3.739933e-4
GO:0030913	paranodal junction assembly	3.739933e-4
GO:0051384	response to glucocorticoid stimulus	3.748413e-4
GO:0001919	regulation of receptor recycling	3.770920e-4
GO:0001503	ossification	3.791258e-4
GO:0000272	polysaccharide catabolic process	4.059874e-4
GO:0071402	cellular response to lipoprotein particle stimulus	4.113277e-4
GO:0030224	monocyte differentiation	4.166118e-4
GO:0048610	cellular process involved in reproduction	4.203100e-4
GO:0060291	long-term synaptic potentiation	4.232485e-4
GO:0045355	negative regulation of interferon-alpha biosynthetic process	4.242104e-4
GO:0034314	Arp2/3 complex-mediated actin nucleation	4.286896e-4
GO:0051580	regulation of neurotransmitter uptake	4.313413e-4
GO:0009607	response to biotic stimulus	4.397899e-4
GO:0050886	endocrine process	4.399370e-4
GO:0048708	astrocyte differentiation	4.582381e-4
GO:0071222	cellular response to lipopolysaccharide	4.641518e-4
GO:0042407	cristae formation	4.707719e-4
GO:0043438	acetoacetic acid metabolic process	4.878718e-4
GO:0007165	signal transduction	5.100117e-4
GO:0051324	prophase	5.394550e-4
GO:0032049	cardiolipin biosynthetic process	5.452737e-4
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	5.570838e-4
GO:0006987	activation of signaling protein activity involved in unfolded protein response	5.570838e-4
GO:0008594	photoreceptor cell morphogenesis	5.599897e-4
GO:0010935	regulation of macrophage cytokine production	5.603981e-4
GO:0046903	secretion	5.682684e-4
GO:0051534	negative regulation of NFAT protein import into nucleus	5.735867e-4
GO:0070098	chemokine-mediated signaling pathway	5.936659e-4
GO:0044255	cellular lipid metabolic process	5.942901e-4
GO:0042446	hormone biosynthetic process	6.128818e-4
GO:0032374	regulation of cholesterol transport	6.222737e-4
GO:0006690	icosanoid metabolic process	6.256496e-4
GO:0035036	sperm-egg recognition	6.304297e-4
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	6.332942e-4
GO:0003408	optic cup formation involved in camera-type eye development	6.496630e-4
GO:0032069	regulation of nuclease activity	6.544276e-4
GO:0055093	response to hyperoxia	6.706469e-4
GO:0021589	cerebellum structural organization	6.987491e-4
GO:0060904	regulation of protein folding in endoplasmic reticulum	6.987491e-4
GO:0009822	alkaloid catabolic process	6.987491e-4
GO:0042994	cytoplasmic sequestering of transcription factor	7.032770e-4
GO:0051707	response to other organism	7.051663e-4
GO:0001516	prostaglandin biosynthetic process	7.419513e-4
GO:0007007	inner mitochondrial membrane organization	7.744097e-4
GO:0007229	integrin-mediated signaling pathway	7.745517e-4
GO:0040012	regulation of locomotion	7.765727e-4
GO:0033559	unsaturated fatty acid metabolic process	7.805622e-4
GO:0001956	positive regulation of neurotransmitter secretion	7.954398e-4
GO:0017156	calcium ion-dependent exocytosis	8.023358e-4
GO:0042692	muscle cell differentiation	8.375559e-4
GO:0003084	positive regulation of systemic arterial blood pressure	8.450301e-4
GO:0008202	steroid metabolic process	8.460776e-4
GO:0035684	helper T cell extravasation	8.595136e-4
GO:0003108	negative regulation of the force of heart contraction by chemical signal	8.595136e-4
GO:0071257	cellular response to electrical stimulus	8.634353e-4
GO:0000216	M/G1 transition of mitotic cell cycle	8.648573e-4
GO:0042758	long-chain fatty acid catabolic process	8.689428e-4
GO:0042413	carnitine catabolic process	8.689428e-4
GO:0046724	oxalic acid secretion	8.689428e-4
GO:0035994	response to muscle stretch	8.689428e-4
GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	8.689428e-4
GO:0051270	regulation of cellular component movement	8.711983e-4
GO:0006693	prostaglandin metabolic process	9.050196e-4
GO:0060067	cervix development	9.296146e-4
GO:0042992	negative regulation of transcription factor import into nucleus	9.314322e-4
GO:0071157	negative regulation of cell cycle arrest	9.534189e-4
GO:0003015	heart process	9.677053e-4
GO:0045039	protein import into mitochondrial inner membrane	9.740183e-4
GO:0018206	peptidyl-methionine modification	9.973384e-4
GO:0002418	immune response to tumor cell	1.000160e-3
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	1.018661e-3
GO:0023052	signaling	1.020911e-3
GO:0032940	secretion by cell	1.027749e-3
GO:0032236	positive regulation of calcium ion transport via store-operated calcium channel activity	1.042261e-3
GO:0003300	cardiac muscle hypertrophy	1.044069e-3
GO:0071219	cellular response to molecule of bacterial origin	1.050212e-3
GO:0009309	amine biosynthetic process	1.075067e-3
GO:0002904	positive regulation of B cell apoptosis	1.079315e-3
GO:0050877	neurological system process	1.089481e-3
GO:0002026	regulation of the force of heart contraction	1.091098e-3
GO:0051590	positive regulation of neurotransmitter transport	1.097248e-3
GO:0033013	tetrapyrrole metabolic process	1.098715e-3
GO:0030155	regulation of cell adhesion	1.107245e-3
GO:0032897	negative regulation of viral transcription	1.116253e-3
GO:0070230	positive regulation of lymphocyte apoptosis	1.124852e-3
GO:0009888	tissue development	1.163361e-3
GO:0006032	chitin catabolic process	1.171206e-3
GO:0030836	positive regulation of actin filament depolymerization	1.171206e-3
GO:0071385	cellular response to glucocorticoid stimulus	1.191234e-3
GO:0002158	osteoclast proliferation	1.194042e-3
GO:0043901	negative regulation of multi-organism process	1.199844e-3
GO:0045981	positive regulation of nucleotide metabolic process	1.204259e-3
GO:0055069	zinc ion homeostasis	1.219254e-3
GO:0048286	lung alveolus development	1.221411e-3
GO:0046456	icosanoid biosynthetic process	1.224954e-3
GO:0042445	hormone metabolic process	1.240078e-3
GO:0051414	response to cortisol stimulus	1.241703e-3
GO:0000305	response to oxygen radical	1.249268e-3
GO:0046628	positive regulation of insulin receptor signaling pathway	1.251093e-3
GO:0019695	choline metabolic process	1.285547e-3
GO:0042737	drug catabolic process	1.286409e-3
GO:0035089	establishment of apical/basal cell polarity	1.286409e-3
GO:0071346	cellular response to interferon-gamma	1.297806e-3
GO:0010897	negative regulation of triglyceride catabolic process	1.316061e-3
GO:0010987	negative regulation of high-density lipoprotein particle clearance	1.316061e-3
GO:0007000	nucleolus organization	1.327651e-3
GO:0006066	alcohol metabolic process	1.332173e-3
GO:0002720	positive regulation of cytokine production involved in immune response	1.338918e-3
GO:0006777	Mo-molybdopterin cofactor biosynthetic process	1.360952e-3
GO:0061350	planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	1.378568e-3
GO:0061354	planar cell polarity pathway involved in pericardium morphogenesis	1.378568e-3
GO:0061349	planar cell polarity pathway involved in cardiac right atrium morphogenesis	1.378568e-3
GO:0060210	metestrus	1.378568e-3
GO:0061347	planar cell polarity pathway involved in outflow tract morphogenesis	1.378568e-3
GO:0061348	planar cell polarity pathway involved in ventricular septum morphogenesis	1.378568e-3
GO:0060463	lung lobe morphogenesis	1.381642e-3
GO:0055013	cardiac muscle cell development	1.387534e-3
GO:0015866	ADP transport	1.388306e-3
GO:0050714	positive regulation of protein secretion	1.405275e-3
GO:0007506	gonadal mesoderm development	1.420438e-3
GO:0048143	astrocyte activation	1.440186e-3
GO:0002718	regulation of cytokine production involved in immune response	1.449076e-3
GO:0070483	detection of hypoxia	1.449880e-3
GO:0030804	positive regulation of cyclic nucleotide biosynthetic process	1.497094e-3
GO:0032414	positive regulation of ion transmembrane transporter activity	1.524701e-3
GO:0014895	smooth muscle hypertrophy	1.535008e-3
GO:0003106	negative regulation of glomerular filtration by angiotensin	1.535008e-3
GO:0051045	negative regulation of membrane protein ectodomain proteolysis	1.546805e-3
GO:2000145	regulation of cell motility	1.563988e-3
GO:0006636	unsaturated fatty acid biosynthetic process	1.566626e-3
GO:0050433	regulation of catecholamine secretion	1.581148e-3
GO:0006766	vitamin metabolic process	1.582896e-3
GO:0000422	mitochondrion degradation	1.599655e-3
GO:0002682	regulation of immune system process	1.628978e-3
GO:0001738	morphogenesis of a polarized epithelium	1.629439e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0071230	cellular response to amino acid stimulus	1.491973e-31
GO:0071229	cellular response to acid	1.516784e-30
GO:0001957	intramembranous ossification	7.636047e-28
GO:0071417	cellular response to organic nitrogen	1.963237e-26
GO:0071418	cellular response to amine stimulus	2.244784e-26
GO:0060346	bone trabecula formation	5.676300e-25
GO:0032964	collagen biosynthetic process	3.347204e-22
GO:0043200	response to amino acid stimulus	1.965798e-20
GO:0010718	positive regulation of epithelial to mesenchymal transition	4.104005e-20
GO:0030199	collagen fibril organization	3.083025e-19
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	1.441791e-18
GO:0010717	regulation of epithelial to mesenchymal transition	2.426359e-18
GO:0034505	tooth mineralization	4.131477e-18
GO:0070208	protein heterotrimerization	5.671475e-18
GO:0001101	response to acid	1.491439e-17
GO:0043589	skin morphogenesis	3.883809e-17
GO:0002740	negative regulation of cytokine secretion involved in immune response	6.513913e-17
GO:0060343	trabecula formation	8.159252e-17
GO:0010987	negative regulation of high-density lipoprotein particle clearance	9.381522e-17
GO:0010897	negative regulation of triglyceride catabolic process	9.381522e-17
GO:0002739	regulation of cytokine secretion involved in immune response	3.904312e-15
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	5.255166e-15
GO:0070508	cholesterol import	6.759232e-15
GO:0010982	regulation of high-density lipoprotein particle clearance	1.300614e-14
GO:0050713	negative regulation of interleukin-1 beta secretion	1.347387e-14
GO:0061383	trabecula morphogenesis	2.944652e-14
GO:0014075	response to amine stimulus	3.970514e-14
GO:0010989	negative regulation of low-density lipoprotein particle clearance	4.167679e-14
GO:0010985	negative regulation of lipoprotein particle clearance	8.307336e-14
GO:0070206	protein trimerization	8.913210e-14
GO:0034382	chylomicron remnant clearance	1.461879e-13
GO:0050711	negative regulation of interleukin-1 secretion	4.877942e-13
GO:0032963	collagen metabolic process	6.442147e-13
GO:0060351	cartilage development involved in endochondral bone morphogenesis	7.816697e-13
GO:0010984	regulation of lipoprotein particle clearance	9.380188e-13
GO:0051005	negative regulation of lipoprotein lipase activity	1.031430e-12
GO:0060621	negative regulation of cholesterol import	1.374374e-12
GO:0071260	cellular response to mechanical stimulus	3.086195e-12
GO:0044259	multicellular organismal macromolecule metabolic process	4.805448e-12
GO:0048730	epidermis morphogenesis	6.855920e-12
GO:0060620	regulation of cholesterol import	7.411625e-12
GO:0001935	endothelial cell proliferation	9.063496e-12
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	9.213705e-12
GO:0044236	multicellular organismal metabolic process	1.182318e-11
GO:0001649	osteoblast differentiation	1.193292e-11
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	1.860703e-11
GO:0034377	plasma lipoprotein particle assembly	2.553390e-11
GO:0030198	extracellular matrix organization	2.654574e-11
GO:0032488	Cdc42 protein signal transduction	3.351256e-11
GO:0050710	negative regulation of cytokine secretion	4.718093e-11
GO:0006695	cholesterol biosynthetic process	9.001003e-11
GO:0001958	endochondral ossification	1.402013e-10
GO:0050995	negative regulation of lipid catabolic process	2.824805e-10
GO:0048261	negative regulation of receptor-mediated endocytosis	3.289960e-10
GO:0032375	negative regulation of cholesterol transport	3.335872e-10
GO:0010873	positive regulation of cholesterol esterification	6.053723e-10
GO:0043588	skin development	7.698601e-10
GO:0060192	negative regulation of lipase activity	7.699662e-10
GO:0016126	sterol biosynthetic process	7.982829e-10
GO:0032800	receptor biosynthetic process	1.000717e-9
GO:0010243	response to organic nitrogen	1.519847e-9
GO:0045717	negative regulation of fatty acid biosynthetic process	1.798832e-9
GO:0060325	face morphogenesis	4.955592e-9
GO:2000054	negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	5.176150e-9
GO:0010872	regulation of cholesterol esterification	6.968982e-9
GO:0034380	high-density lipoprotein particle assembly	7.622115e-9
GO:0032691	negative regulation of interleukin-1 beta production	8.679010e-9
GO:0060323	head morphogenesis	1.051539e-8
GO:0045212	neurotransmitter receptor biosynthetic process	1.174927e-8
GO:0032930	positive regulation of superoxide anion generation	1.174927e-8
GO:0065005	protein-lipid complex assembly	1.224728e-8
GO:0060349	bone morphogenesis	1.298657e-8
GO:0031214	biomineral tissue development	1.344108e-8
GO:0050709	negative regulation of protein secretion	1.394184e-8
GO:0007584	response to nutrient	1.420825e-8
GO:0071295	cellular response to vitamin	1.444514e-8
GO:0048259	regulation of receptor-mediated endocytosis	1.595800e-8
GO:0060350	endochondral bone morphogenesis	1.612793e-8
GO:0010812	negative regulation of cell-substrate adhesion	1.691332e-8
GO:0034375	high-density lipoprotein particle remodeling	2.078320e-8
GO:0090209	negative regulation of triglyceride metabolic process	2.126084e-8
GO:0045806	negative regulation of endocytosis	2.266321e-8
GO:0032651	regulation of interleukin-1 beta production	2.319792e-8
GO:0032692	negative regulation of interleukin-1 production	2.750532e-8
GO:0008542	visual learning	3.462392e-8
GO:0006642	triglyceride mobilization	3.621376e-8
GO:0071356	cellular response to tumor necrosis factor	3.713626e-8
GO:0032928	regulation of superoxide anion generation	3.954228e-8
GO:0030177	positive regulation of Wnt receptor signaling pathway	3.955918e-8
GO:2000053	regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	5.798007e-8
GO:0034612	response to tumor necrosis factor	5.858904e-8
GO:0032652	regulation of interleukin-1 production	7.045845e-8
GO:0045922	negative regulation of fatty acid metabolic process	7.048149e-8
GO:0007162	negative regulation of cell adhesion	8.401327e-8
GO:0006694	steroid biosynthetic process	1.063230e-7
GO:0019915	lipid storage	1.089836e-7
GO:0033273	response to vitamin	1.261375e-7
GO:0016191	synaptic vesicle uncoating	1.357801e-7
GO:0071300	cellular response to retinoic acid	1.745095e-7
GO:0071299	cellular response to vitamin A	2.473509e-7
GO:0001503	ossification	2.655921e-7
GO:0030261	chromosome condensation	2.720235e-7
GO:0071214	cellular response to abiotic stimulus	2.880311e-7
GO:0031670	cellular response to nutrient	3.257228e-7
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	3.352788e-7
GO:0060828	regulation of canonical Wnt receptor signaling pathway	3.576426e-7
GO:0032682	negative regulation of chemokine production	5.223650e-7
GO:0060693	regulation of branching involved in salivary gland morphogenesis	5.249347e-7
GO:2000256	positive regulation of male germ cell proliferation	5.527741e-7
GO:0042231	interleukin-13 biosynthetic process	5.527741e-7
GO:0001579	medium-chain fatty acid transport	5.527741e-7
GO:0033189	response to vitamin A	5.529950e-7
GO:0034381	plasma lipoprotein particle clearance	5.641401e-7
GO:0090322	regulation of superoxide metabolic process	5.673364e-7
GO:0043534	blood vessel endothelial cell migration	6.134739e-7
GO:0060191	regulation of lipase activity	6.639730e-7
GO:0032526	response to retinoic acid	6.889372e-7
GO:0046069	cGMP catabolic process	7.864468e-7
GO:0045940	positive regulation of steroid metabolic process	8.118339e-7
GO:0033700	phospholipid efflux	8.526158e-7
GO:0003012	muscle system process	9.113759e-7
GO:0002642	positive regulation of immunoglobulin biosynthetic process	9.523023e-7
GO:0010896	regulation of triglyceride catabolic process	9.934622e-7
GO:0010951	negative regulation of endopeptidase activity	1.149321e-6
GO:0007338	single fertilization	1.275391e-6
GO:0010171	body morphogenesis	1.727713e-6
GO:0030300	regulation of intestinal cholesterol absorption	2.195312e-6
GO:0070328	triglyceride homeostasis	2.420301e-6
GO:0051291	protein heterooligomerization	2.446966e-6
GO:0001887	selenium compound metabolic process	2.663495e-6
GO:0007632	visual behavior	2.665050e-6
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	2.993083e-6
GO:0010720	positive regulation of cell development	3.215771e-6
GO:0071495	cellular response to endogenous stimulus	3.623699e-6
GO:0050673	epithelial cell proliferation	3.721991e-6
GO:0061028	establishment of endothelial barrier	3.857990e-6
GO:0006629	lipid metabolic process	4.028152e-6
GO:0032374	regulation of cholesterol transport	4.311301e-6
GO:0060324	face development	4.393849e-6
GO:0060348	bone development	4.514614e-6
GO:0071827	plasma lipoprotein particle organization	4.729760e-6
GO:0034104	negative regulation of tissue remodeling	4.925410e-6
GO:0046068	cGMP metabolic process	5.021213e-6
GO:0006641	triglyceride metabolic process	5.163821e-6
GO:0030111	regulation of Wnt receptor signaling pathway	5.306755e-6
GO:0050706	regulation of interleukin-1 beta secretion	5.435508e-6
GO:0048705	skeletal system morphogenesis	5.707002e-6
GO:0006639	acylglycerol metabolic process	6.032847e-6
GO:0051224	negative regulation of protein transport	6.149833e-6
GO:0090207	regulation of triglyceride metabolic process	6.199658e-6
GO:0043691	reverse cholesterol transport	7.186501e-6
GO:0061302	smooth muscle cell-matrix adhesion	7.941690e-6
GO:2000270	negative regulation of fibroblast apoptosis	8.554767e-6
GO:2000271	positive regulation of fibroblast apoptosis	8.554767e-6
GO:2000080	negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	8.554767e-6
GO:0044345	stromal-epithelial cell signaling involved in prostate gland development	8.554767e-6
GO:0008211	glucocorticoid metabolic process	8.708391e-6
GO:0032369	negative regulation of lipid transport	8.715456e-6
GO:0050707	regulation of cytokine secretion	9.458011e-6
GO:0006638	neutral lipid metabolic process	9.952321e-6
GO:0050994	regulation of lipid catabolic process	1.127669e-5
GO:0045085	negative regulation of interleukin-2 biosynthetic process	1.197107e-5
GO:0046486	glycerolipid metabolic process	1.210196e-5
GO:0050704	regulation of interleukin-1 secretion	1.290193e-5
GO:2000079	regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	1.387649e-5
GO:0071380	cellular response to prostaglandin E stimulus	1.387649e-5
GO:0042095	interferon-gamma biosynthetic process	1.387649e-5
GO:0006936	muscle contraction	1.426178e-5
GO:0010817	regulation of hormone levels	1.496890e-5
GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport	1.516858e-5
GO:0006710	androgen catabolic process	1.516858e-5
GO:0022603	regulation of anatomical structure morphogenesis	1.858260e-5
GO:0044255	cellular lipid metabolic process	1.895543e-5
GO:0008203	cholesterol metabolic process	1.907974e-5
GO:0044058	regulation of digestive system process	1.945462e-5
GO:0033344	cholesterol efflux	2.050004e-5
GO:0051382	kinetochore assembly	2.166703e-5
GO:0046464	acylglycerol catabolic process	2.292200e-5
GO:0006939	smooth muscle contraction	2.504479e-5
GO:0006927	transformed cell apoptosis	2.620417e-5
GO:0051142	positive regulation of NK T cell proliferation	2.690377e-5
GO:0016042	lipid catabolic process	2.717408e-5
GO:0016125	sterol metabolic process	2.840318e-5
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	2.911779e-5
GO:0007266	Rho protein signal transduction	3.020124e-5
GO:0051004	regulation of lipoprotein lipase activity	3.112598e-5
GO:0019433	triglyceride catabolic process	3.620551e-5
GO:0051533	positive regulation of NFAT protein import into nucleus	3.845084e-5
GO:0043117	positive regulation of vascular permeability	3.845084e-5
GO:0042304	regulation of fatty acid biosynthetic process	3.852842e-5
GO:0071363	cellular response to growth factor stimulus	3.929431e-5
GO:0001944	vasculature development	3.952446e-5
GO:0061181	regulation of chondrocyte development	3.986879e-5
GO:0097006	regulation of plasma lipoprotein particle levels	4.006845e-5
GO:0033689	negative regulation of osteoblast proliferation	4.264778e-5
GO:0008610	lipid biosynthetic process	4.464800e-5
GO:0002718	regulation of cytokine production involved in immune response	4.561323e-5
GO:0045994	positive regulation of translational initiation by iron	4.806071e-5
GO:0061048	negative regulation of branching involved in lung morphogenesis	4.806071e-5
GO:0034116	positive regulation of heterotypic cell-cell adhesion	4.806071e-5
GO:0002037	negative regulation of L-glutamate transport	4.806071e-5
GO:0042158	lipoprotein biosynthetic process	4.918100e-5
GO:0070305	response to cGMP	4.984313e-5
GO:0043542	endothelial cell migration	6.035844e-5
GO:0008202	steroid metabolic process	6.078680e-5
GO:0045076	regulation of interleukin-2 biosynthetic process	6.230287e-5
GO:0008544	epidermis development	6.975954e-5
GO:0051346	negative regulation of hydrolase activity	6.994461e-5
GO:0033143	regulation of steroid hormone receptor signaling pathway	7.072181e-5
GO:0048565	digestive tract development	7.473891e-5
GO:0060322	head development	7.564621e-5
GO:0017156	calcium ion-dependent exocytosis	7.666975e-5
GO:0002318	myeloid progenitor cell differentiation	7.926154e-5
GO:0032757	positive regulation of interleukin-8 production	8.514814e-5
GO:0046641	positive regulation of alpha-beta T cell proliferation	8.606640e-5
GO:0042445	hormone metabolic process	8.793862e-5
GO:0030100	regulation of endocytosis	9.135302e-5
GO:0034103	regulation of tissue remodeling	9.410745e-5
GO:2000275	regulation of oxidative phosphorylation uncoupler activity	9.501119e-5
GO:0060627	regulation of vesicle-mediated transport	9.567340e-5
GO:0051383	kinetochore organization	9.629758e-5
GO:0009992	cellular water homeostasis	9.629758e-5
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	9.629758e-5
GO:0051261	protein depolymerization	9.715799e-5
GO:0030325	adrenal gland development	1.082908e-4
GO:0007202	activation of phospholipase C activity	1.089634e-4
GO:0033146	regulation of estrogen receptor signaling pathway	1.132576e-4
GO:0014819	regulation of skeletal muscle contraction	1.132576e-4
GO:0071321	cellular response to cGMP	1.235697e-4
GO:0006581	acetylcholine catabolic process	1.235697e-4
GO:0014034	neural crest cell fate commitment	1.278908e-4
GO:0031647	regulation of protein stability	1.305748e-4
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	1.321148e-4
GO:0034695	response to prostaglandin E stimulus	1.417019e-4
GO:0008625	induction of apoptosis via death domain receptors	1.426192e-4
GO:0018904	organic ether metabolic process	1.430966e-4
GO:0015914	phospholipid transport	1.521904e-4
GO:0010939	regulation of necrotic cell death	1.533324e-4
GO:0007166	cell surface receptor linked signaling pathway	1.563524e-4
GO:0034369	plasma lipoprotein particle remodeling	1.569251e-4
GO:0002115	store-operated calcium entry	1.588545e-4
GO:0002921	negative regulation of humoral immune response	1.610938e-4
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	1.615036e-4
GO:0003008	system process	1.648622e-4
GO:0050821	protein stabilization	1.691278e-4
GO:0006662	glycerol ether metabolic process	1.700224e-4
GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus	1.780163e-4
GO:0032642	regulation of chemokine production	1.781092e-4
GO:0071504	cellular response to heparin	1.845312e-4
GO:0031667	response to nutrient levels	1.848842e-4
GO:0006650	glycerophospholipid metabolic process	1.886834e-4
GO:0071845	cellular component disassembly at cellular level	1.895887e-4
GO:0009214	cyclic nucleotide catabolic process	1.941298e-4
GO:0042439	ethanolamine-containing compound metabolic process	2.031916e-4
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	2.097625e-4
GO:0022604	regulation of cell morphogenesis	2.181007e-4
GO:0030449	regulation of complement activation	2.209837e-4
GO:0055123	digestive system development	2.226411e-4
GO:0001885	endothelial cell development	2.247290e-4
GO:0032368	regulation of lipid transport	2.271532e-4
GO:0046503	glycerolipid catabolic process	2.285392e-4
GO:0051901	positive regulation of mitochondrial depolarization	2.347344e-4
GO:0060555	induction of necroptosis by extracellular signals	2.381400e-4
GO:0008306	associative learning	2.386180e-4
GO:0022411	cellular component disassembly	2.417154e-4
GO:0034623	cellular macromolecular complex disassembly	2.425381e-4
GO:0006198	cAMP catabolic process	2.425381e-4
GO:0045214	sarcomere organization	2.427467e-4
GO:0045213	neurotransmitter receptor metabolic process	2.435194e-4
GO:0035414	negative regulation of catenin import into nucleus	2.456726e-4
GO:0071503	response to heparin	2.459874e-4
GO:0045834	positive regulation of lipid metabolic process	2.522705e-4
GO:0001963	synaptic transmission, dopaminergic	2.721690e-4
GO:0003084	positive regulation of systemic arterial blood pressure	2.721690e-4
GO:0014874	response to stimulus involved in regulation of muscle adaptation	2.738110e-4
GO:0010769	regulation of cell morphogenesis involved in differentiation	2.824109e-4
GO:0010543	regulation of platelet activation	2.942934e-4
GO:0007440	foregut morphogenesis	3.120420e-4
GO:0010863	positive regulation of phospholipase C activity	3.134357e-4
GO:0060688	regulation of morphogenesis of a branching structure	3.235937e-4
GO:0002861	regulation of inflammatory response to antigenic stimulus	3.273559e-4
GO:0001568	blood vessel development	3.307383e-4
GO:0046470	phosphatidylcholine metabolic process	3.384336e-4
GO:0072358	cardiovascular system development	3.400621e-4
GO:0043462	regulation of ATPase activity	3.438729e-4
GO:0045916	negative regulation of complement activation	3.484199e-4
GO:0035412	regulation of catenin import into nucleus	3.623720e-4
GO:0048706	embryonic skeletal system development	3.632102e-4
GO:0002678	positive regulation of chronic inflammatory response	3.685551e-4
GO:0043438	acetoacetic acid metabolic process	3.691525e-4
GO:0042632	cholesterol homeostasis	3.756535e-4
GO:0032984	macromolecular complex disassembly	3.779154e-4
GO:0008291	acetylcholine metabolic process	3.923673e-4
GO:0015760	glucose-6-phosphate transport	3.923673e-4
GO:0072240	metanephric DCT cell differentiation	3.972187e-4
GO:2000117	negative regulation of cysteine-type endopeptidase activity	3.972187e-4
GO:0072227	metanephric macula densa development	3.972187e-4
GO:0002036	regulation of L-glutamate transport	3.972187e-4
GO:0032423	regulation of mismatch repair	4.038076e-4
GO:0014029	neural crest formation	4.038076e-4
GO:0010876	lipid localization	4.094606e-4
GO:0008624	induction of apoptosis by extracellular signals	4.170969e-4
GO:0090244	Wnt receptor signaling pathway involved in somitogenesis	4.176197e-4
GO:0071316	cellular response to nicotine	4.176197e-4
GO:0007186	G-protein coupled receptor protein signaling pathway	4.347998e-4
GO:0046640	regulation of alpha-beta T cell proliferation	4.570050e-4
GO:0044341	sodium-dependent phosphate transport	4.723149e-4
GO:0000185	activation of MAPKKK activity	4.977351e-4
GO:0001818	negative regulation of cytokine production	5.039710e-4
GO:0072520	seminiferous tubule development	5.055784e-4
GO:0060557	positive regulation of vitamin D biosynthetic process	5.055784e-4
GO:0002019	regulation of renal output by angiotensin	5.055784e-4
GO:0032103	positive regulation of response to external stimulus	5.221463e-4
GO:0002920	regulation of humoral immune response	5.451067e-4
GO:0043137	DNA replication, removal of RNA primer	5.492555e-4
GO:0032971	regulation of muscle filament sliding	5.492555e-4
GO:0051048	negative regulation of secretion	5.690079e-4
GO:0009950	dorsal/ventral axis specification	5.818367e-4
GO:0060312	regulation of blood vessel remodeling	5.857623e-4
GO:0001869	negative regulation of complement activation, lectin pathway	5.898902e-4
GO:0072530	purine-containing compound transmembrane transport	6.154679e-4
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	6.331164e-4
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	6.416753e-4
GO:0010518	positive regulation of phospholipase activity	6.891665e-4
GO:0009991	response to extracellular stimulus	6.895086e-4
GO:0010155	regulation of proton transport	6.942462e-4
GO:0034379	very-low-density lipoprotein particle assembly	6.958654e-4
GO:0002697	regulation of immune effector process	6.963351e-4
GO:0050727	regulation of inflammatory response	7.005999e-4
GO:0070602	regulation of centromeric sister chromatid cohesion	7.078614e-4
GO:0051259	protein oligomerization	7.195382e-4
GO:0007612	learning	7.200376e-4
GO:0044242	cellular lipid catabolic process	7.434434e-4
GO:0034097	response to cytokine stimulus	7.479658e-4
GO:0043624	cellular protein complex disassembly	7.584313e-4
GO:0001555	oocyte growth	7.749875e-4
GO:0006887	exocytosis	7.884808e-4
GO:0001990	regulation of systemic arterial blood pressure by hormone	8.036381e-4
GO:0010940	positive regulation of necrotic cell death	8.166790e-4
GO:0001955	blood vessel maturation	8.166790e-4
GO:0046488	phosphatidylinositol metabolic process	8.221992e-4
GO:0019953	sexual reproduction	8.469362e-4
GO:0072017	distal tubule development	8.585591e-4
GO:0051241	negative regulation of multicellular organismal process	9.030443e-4
GO:0034508	centromere complex assembly	9.540064e-4
GO:0006810	transport	9.571364e-4
GO:0071345	cellular response to cytokine stimulus	9.620014e-4
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	9.754347e-4
GO:0042447	hormone catabolic process	9.760630e-4
GO:0071803	positive regulation of podosome assembly	9.769715e-4
GO:0060684	epithelial-mesenchymal cell signaling	9.836231e-4
GO:0009187	cyclic nucleotide metabolic process	1.010139e-3
GO:0009125	nucleoside monophosphate catabolic process	1.026117e-3
GO:0043114	regulation of vascular permeability	1.029332e-3
GO:0050850	positive regulation of calcium-mediated signaling	1.069140e-3
GO:0046851	negative regulation of bone remodeling	1.093014e-3
GO:0006273	lagging strand elongation	1.096588e-3
GO:0006656	phosphatidylcholine biosynthetic process	1.105474e-3
GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger	1.126509e-3
GO:0032729	positive regulation of interferon-gamma production	1.138397e-3
GO:0033159	negative regulation of protein import into nucleus, translocation	1.193956e-3
GO:0072218	metanephric ascending thin limb development	1.193956e-3
GO:0072233	metanephric thick ascending limb development	1.193956e-3
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	1.193956e-3
GO:0045668	negative regulation of osteoblast differentiation	1.219380e-3
GO:0010517	regulation of phospholipase activity	1.256899e-3
GO:0014827	intestine smooth muscle contraction	1.261762e-3
GO:0051272	positive regulation of cellular component movement	1.273238e-3
GO:0015793	glycerol transport	1.276506e-3
GO:0034762	regulation of transmembrane transport	1.286382e-3
GO:0043241	protein complex disassembly	1.310429e-3
GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway	1.358460e-3
GO:0060248	detection of cell density by contact stimulus involved in contact inhibition	1.358460e-3
GO:0072285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	1.358460e-3
GO:0032620	interleukin-17 production	1.358460e-3
GO:0002365	gamma-delta T cell lineage commitment	1.358460e-3
GO:0007371	ventral midline determination	1.358460e-3
GO:0046903	secretion	1.424323e-3
GO:0033147	negative regulation of estrogen receptor signaling pathway	1.446922e-3
GO:0071773	cellular response to BMP stimulus	1.481738e-3
GO:0071481	cellular response to X-ray	1.481738e-3
GO:0032411	positive regulation of transporter activity	1.518946e-3
GO:0071392	cellular response to estradiol stimulus	1.519146e-3
GO:0071374	cellular response to parathyroid hormone stimulus	1.519146e-3
GO:0009566	fertilization	1.540595e-3
GO:0042157	lipoprotein metabolic process	1.597817e-3
GO:0022616	DNA strand elongation	1.605091e-3
GO:0071107	response to parathyroid hormone stimulus	1.625478e-3
GO:0031347	regulation of defense response	1.627569e-3
GO:0009895	negative regulation of catabolic process	1.673085e-3
GO:0045060	negative thymic T cell selection	1.682280e-3
GO:0030335	positive regulation of cell migration	1.699751e-3
GO:2000147	positive regulation of cell motility	1.706051e-3
GO:0051583	dopamine uptake	1.739786e-3
GO:0015747	urate transport	1.739786e-3
GO:0042993	positive regulation of transcription factor import into nucleus	1.755262e-3
GO:0006323	DNA packaging	1.760284e-3
GO:0040017	positive regulation of locomotion	1.790728e-3
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	1.857432e-3
GO:0008065	establishment of blood-nerve barrier	1.899985e-3
GO:0014873	response to muscle activity involved in regulation of muscle adaptation	1.899985e-3
GO:0061049	cell growth involved in cardiac muscle cell development	1.899985e-3
GO:0003331	positive regulation of extracellular matrix constituent secretion	1.899985e-3
GO:0001834	trophectodermal cell proliferation	1.899985e-3
GO:0002017	regulation of blood volume by renal aldosterone	1.899985e-3
GO:0015908	fatty acid transport	1.916421e-3
GO:0050927	positive regulation of positive chemotaxis	1.935992e-3
GO:0007588	excretion	2.057824e-3
GO:0007614	short-term memory	2.061913e-3
GO:0070172	positive regulation of tooth mineralization	2.076641e-3
GO:0006583	melanin biosynthetic process from tyrosine	2.076641e-3
GO:0032101	regulation of response to external stimulus	2.142453e-3
GO:0032722	positive regulation of chemokine production	2.182600e-3
GO:0010900	negative regulation of phosphatidylcholine catabolic process	2.246870e-3
GO:0051055	negative regulation of lipid biosynthetic process	2.352094e-3
GO:0046463	acylglycerol biosynthetic process	2.357531e-3
GO:0046504	glycerol ether biosynthetic process	2.397471e-3
GO:0045833	negative regulation of lipid metabolic process	2.409909e-3
GO:0042476	odontogenesis	2.458428e-3
GO:0051897	positive regulation of protein kinase B signaling cascade	2.475063e-3
GO:0051900	regulation of mitochondrial depolarization	2.504912e-3
GO:0003300	cardiac muscle hypertrophy	2.504912e-3
GO:0006631	fatty acid metabolic process	2.506806e-3
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	2.568481e-3
GO:0043383	negative T cell selection	2.572833e-3
GO:0016082	synaptic vesicle priming	2.595678e-3
GO:0032474	otolith morphogenesis	2.609940e-3
GO:0003106	negative regulation of glomerular filtration by angiotensin	2.609940e-3
GO:0014895	smooth muscle hypertrophy	2.609940e-3
GO:0071347	cellular response to interleukin-1	2.619680e-3
GO:0051896	regulation of protein kinase B signaling cascade	2.638510e-3
GO:0003254	regulation of membrane depolarization	2.708944e-3
GO:0030239	myofibril assembly	2.718128e-3
GO:0045299	otolith mineralization	2.731218e-3
GO:0008039	synaptic target recognition	2.731218e-3
GO:0050901	leukocyte tethering or rolling	2.753808e-3
GO:0050926	regulation of positive chemotaxis	2.773228e-3
GO:0071312	cellular response to alkaloid	2.802711e-3
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway	2.802711e-3
GO:0045948	positive regulation of translational initiation	2.859988e-3
GO:0045017	glycerolipid biosynthetic process	2.862890e-3
GO:0009612	response to mechanical stimulus	2.869256e-3
GO:0003230	cardiac atrium development	2.872821e-3
GO:0043206	fibril organization	2.884942e-3
GO:0016554	cytidine to uridine editing	2.899463e-3
GO:0010572	positive regulation of platelet activation	2.899463e-3
GO:0006461	protein complex assembly	2.906035e-3
GO:0051567	histone H3-K9 methylation	2.935997e-3
GO:0014896	muscle hypertrophy	2.961729e-3
GO:0006106	fumarate metabolic process	2.980818e-3
GO:0090200	positive regulation of release of cytochrome c from mitochondria	3.039047e-3
GO:0002016	regulation of blood volume by renin-angiotensin	3.039047e-3
GO:0071822	protein complex subunit organization	3.052849e-3
GO:0032770	positive regulation of monooxygenase activity	3.114117e-3
GO:0006869	lipid transport	3.122644e-3
GO:0050848	regulation of calcium-mediated signaling	3.158541e-3
GO:0042542	response to hydrogen peroxide	3.180985e-3
GO:0014910	regulation of smooth muscle cell migration	3.244308e-3
GO:0019605	butyrate metabolic process	3.261749e-3
GO:0070271	protein complex biogenesis	3.287336e-3
GO:0019432	triglyceride biosynthetic process	3.291449e-3
GO:0034763	negative regulation of transmembrane transport	3.364592e-3
GO:0097012	response to granulocyte macrophage colony-stimulating factor stimulus	3.394341e-3
GO:0019217	regulation of fatty acid metabolic process	3.400743e-3
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	3.553254e-3
GO:0071310	cellular response to organic substance	3.555815e-3
GO:0045061	thymic T cell selection	3.588500e-3
GO:0006897	endocytosis	3.594825e-3
GO:0010544	negative regulation of platelet activation	3.641944e-3
GO:0048266	behavioral response to pain	3.671669e-3
GO:0055088	lipid homeostasis	3.720381e-3
GO:0048255	mRNA stabilization	3.751787e-3
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	3.781025e-3
GO:0009589	detection of UV	3.781025e-3
GO:0048016	inositol phosphate-mediated signaling	3.808930e-3
GO:0042761	very long-chain fatty acid biosynthetic process	3.847658e-3
GO:0030262	apoptotic nuclear change	3.867974e-3
GO:0030155	regulation of cell adhesion	3.875062e-3
GO:0035815	positive regulation of renal sodium excretion	3.900123e-3
GO:0002691	regulation of cellular extravasation	3.900123e-3
GO:0048840	otolith development	3.950995e-3
GO:0030730	sequestering of triglyceride	3.950995e-3
GO:0051532	regulation of NFAT protein import into nucleus	3.957689e-3
GO:0007265	Ras protein signal transduction	3.962102e-3
GO:0051234	establishment of localization	3.963148e-3
GO:0001501	skeletal system development	3.971738e-3
GO:0042088	T-helper 1 type immune response	3.983433e-3
GO:0050708	regulation of protein secretion	4.054590e-3
GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	4.096705e-3
GO:0030970	retrograde protein transport, ER to cytosol	4.096705e-3
GO:0034389	lipid particle organization	4.096705e-3
GO:0070848	response to growth factor stimulus	4.158525e-3
GO:0034694	response to prostaglandin stimulus	4.202729e-3
GO:0003270	Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation	4.292508e-3
GO:0014807	regulation of somitogenesis	4.292508e-3
GO:0014821	phasic smooth muscle contraction	4.332166e-3
GO:0033622	integrin activation	4.388057e-3
GO:0051336	regulation of hydrolase activity	4.478687e-3
GO:0045933	positive regulation of muscle contraction	4.509557e-3
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	4.522376e-3