Novel motif:159

name:	motif159_ACACATACTACA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0032501	multicellular organismal process	1.387096e-25
GO:0043503	skeletal muscle fiber adaptation	1.296715e-24
GO:0043500	muscle adaptation	2.553193e-20
GO:0001970	positive regulation of activation of membrane attack complex	1.748939e-19
GO:0014829	vascular smooth muscle contraction	2.431212e-19
GO:0007275	multicellular organismal development	6.618622e-18
GO:0009611	response to wounding	7.574499e-18
GO:0048731	system development	1.250705e-17
GO:0006954	inflammatory response	1.267379e-17
GO:0048856	anatomical structure development	7.834971e-17
GO:0048513	organ development	9.925624e-17
GO:0032502	developmental process	1.403491e-16
GO:0014888	striated muscle adaptation	9.297441e-16
GO:0043501	skeletal muscle adaptation	9.341357e-16
GO:0050896	response to stimulus	1.380573e-15
GO:0010575	positive regulation vascular endothelial growth factor production	2.768358e-15
GO:0001798	positive regulation of type IIa hypersensitivity	4.101675e-15
GO:0031032	actomyosin structure organization	8.758079e-14
GO:0065008	regulation of biological quality	1.200358e-13
GO:0008588	release of cytoplasmic sequestered NF-kappaB	2.576546e-13
GO:0007586	digestion	2.915237e-13
GO:0010927	cellular component assembly involved in morphogenesis	7.904525e-13
GO:0001819	positive regulation of cytokine production	1.088292e-12
GO:0006952	defense response	1.334538e-12
GO:0010954	positive regulation of protein processing	1.823469e-12
GO:0030239	myofibril assembly	3.770066e-12
GO:0030449	regulation of complement activation	1.148380e-11
GO:0003012	muscle system process	1.456485e-11
GO:0043206	fibril organization	2.310727e-11
GO:0051592	response to calcium ion	2.368619e-11
GO:0065007	biological regulation	3.013365e-11
GO:0032103	positive regulation of response to external stimulus	3.808445e-11
GO:0046578	regulation of Ras protein signal transduction	4.011804e-11
GO:0042310	vasoconstriction	4.388906e-11
GO:0006939	smooth muscle contraction	4.519576e-11
GO:0030154	cell differentiation	5.559853e-11
GO:0030003	cellular cation homeostasis	5.617177e-11
GO:0006957	complement activation, alternative pathway	6.910931e-11
GO:0010574	regulation of vascular endothelial growth factor production	7.821501e-11
GO:0002885	positive regulation of hypersensitivity	9.336289e-11
GO:0050729	positive regulation of inflammatory response	1.119802e-10
GO:0080134	regulation of response to stress	1.442124e-10
GO:0030029	actin filament-based process	1.574484e-10
GO:0030004	cellular monovalent inorganic cation homeostasis	1.873361e-10
GO:0071732	cellular response to nitric oxide	2.370830e-10
GO:0002376	immune system process	3.181218e-10
GO:0007154	cell communication	3.420516e-10
GO:0031349	positive regulation of defense response	3.469204e-10
GO:0045851	pH reduction	3.995588e-10
GO:0051453	regulation of intracellular pH	4.672579e-10
GO:0048869	cellular developmental process	4.883684e-10
GO:0009605	response to external stimulus	4.892793e-10
GO:0016192	vesicle-mediated transport	6.802390e-10
GO:0006875	cellular metal ion homeostasis	7.084567e-10
GO:0051452	intracellular pH reduction	7.983904e-10
GO:0006955	immune response	8.184618e-10
GO:0009888	tissue development	8.283199e-10
GO:0030641	regulation of cellular pH	9.307942e-10
GO:0006950	response to stress	9.885772e-10
GO:0008283	cell proliferation	1.041125e-9
GO:0032101	regulation of response to external stimulus	1.115796e-9
GO:0002883	regulation of hypersensitivity	1.314629e-9
GO:0048583	regulation of response to stimulus	1.318647e-9
GO:0007155	cell adhesion	1.376954e-9
GO:0042060	wound healing	1.853952e-9
GO:0023052	signaling	2.317765e-9
GO:0045214	sarcomere organization	2.403065e-9
GO:0070252	actin-mediated cell contraction	2.539359e-9
GO:0021761	limbic system development	3.396072e-9
GO:2001021	negative regulation of response to DNA damage stimulus	3.617490e-9
GO:0051179	localization	3.749430e-9
GO:0030049	muscle filament sliding	3.756081e-9
GO:0043090	amino acid import	4.203897e-9
GO:0030277	maintenance of gastrointestinal epithelium	4.208829e-9
GO:0051716	cellular response to stimulus	4.543355e-9
GO:0007035	vacuolar acidification	4.761148e-9
GO:0055065	metal ion homeostasis	7.021742e-9
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	7.561061e-9
GO:0051239	regulation of multicellular organismal process	8.057460e-9
GO:0009991	response to extracellular stimulus	8.210817e-9
GO:0055080	cation homeostasis	8.360913e-9
GO:0051050	positive regulation of transport	9.178819e-9
GO:0016197	endosome transport	9.744951e-9
GO:0006936	muscle contraction	9.812409e-9
GO:0009653	anatomical structure morphogenesis	1.007666e-8
GO:0003008	system process	1.107003e-8
GO:0070613	regulation of protein processing	1.146508e-8
GO:0045807	positive regulation of endocytosis	1.148117e-8
GO:0009612	response to mechanical stimulus	1.227227e-8
GO:0006810	transport	1.430428e-8
GO:0050766	positive regulation of phagocytosis	1.431493e-8
GO:0007186	G-protein coupled receptor protein signaling pathway	1.698646e-8
GO:0051234	establishment of localization	1.749626e-8
GO:0051056	regulation of small GTPase mediated signal transduction	1.992770e-8
GO:0042098	T cell proliferation	2.054569e-8
GO:0007166	cell surface receptor linked signaling pathway	2.162171e-8
GO:0050727	regulation of inflammatory response	2.430894e-8
GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport	2.748754e-8
GO:0007173	epidermal growth factor receptor signaling pathway	3.054078e-8
GO:0007584	response to nutrient	3.099635e-8
GO:0031347	regulation of defense response	3.433117e-8
GO:0043067	regulation of programmed cell death	3.460266e-8
GO:0051240	positive regulation of multicellular organismal process	3.689020e-8
GO:0006879	cellular iron ion homeostasis	3.834600e-8
GO:0045766	positive regulation of angiogenesis	4.040626e-8
GO:0001817	regulation of cytokine production	4.323454e-8
GO:0010951	negative regulation of endopeptidase activity	4.611958e-8
GO:0048518	positive regulation of biological process	4.631956e-8
GO:0006788	heme oxidation	4.813107e-8
GO:0010941	regulation of cell death	5.066357e-8
GO:0021854	hypothalamus development	5.442830e-8
GO:0033591	response to L-ascorbic acid	5.481414e-8
GO:0016043	cellular component organization	6.761836e-8
GO:0002708	positive regulation of lymphocyte mediated immunity	6.798199e-8
GO:0002675	positive regulation of acute inflammatory response	7.383818e-8
GO:0007218	neuropeptide signaling pathway	8.178000e-8
GO:0051877	pigment granule aggregation in cell center	8.681776e-8
GO:0030048	actin filament-based movement	9.565283e-8
GO:0042981	regulation of apoptosis	9.733923e-8
GO:0032642	regulation of chemokine production	9.849889e-8
GO:0046697	decidualization	1.060210e-7
GO:0043092	L-amino acid import	1.099352e-7
GO:0014910	regulation of smooth muscle cell migration	1.114579e-7
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	1.114742e-7
GO:0045765	regulation of angiogenesis	1.220346e-7
GO:0070849	response to epidermal growth factor stimulus	1.310219e-7
GO:0009628	response to abiotic stimulus	1.478869e-7
GO:0007320	insemination	1.585651e-7
GO:0014866	skeletal myofibril assembly	1.633864e-7
GO:0042592	homeostatic process	1.656237e-7
GO:0060216	definitive hemopoiesis	1.789169e-7
GO:2000026	regulation of multicellular organismal development	2.010334e-7
GO:0030036	actin cytoskeleton organization	2.022020e-7
GO:0002821	positive regulation of adaptive immune response	2.118841e-7
GO:0032781	positive regulation of ATPase activity	2.123803e-7
GO:0006956	complement activation	2.208848e-7
GO:0042730	fibrinolysis	2.595788e-7
GO:0040007	growth	2.609868e-7
GO:0007165	signal transduction	3.203296e-7
GO:0042346	positive regulation of NF-kappaB import into nucleus	3.336120e-7
GO:0051649	establishment of localization in cell	3.598601e-7
GO:0051641	cellular localization	4.050825e-7
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	4.342046e-7
GO:0050789	regulation of biological process	4.900484e-7
GO:0050794	regulation of cellular process	5.649233e-7
GO:0030198	extracellular matrix organization	6.938432e-7
GO:0007618	mating	7.050311e-7
GO:0048522	positive regulation of cellular process	7.160297e-7
GO:0050793	regulation of developmental process	8.862482e-7
GO:0071816	tail-anchored membrane protein insertion into ER membrane	8.876067e-7
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	9.051882e-7
GO:0051336	regulation of hydrolase activity	9.388271e-7
GO:0071840	cellular component organization or biogenesis	9.533934e-7
GO:0051346	negative regulation of hydrolase activity	1.031567e-6
GO:0006958	complement activation, classical pathway	1.077585e-6
GO:0051057	positive regulation of small GTPase mediated signal transduction	1.079804e-6
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	1.129622e-6
GO:0035691	macrophage migration inhibitory factor signaling pathway	1.129622e-6
GO:0007530	sex determination	1.137776e-6
GO:0055093	response to hyperoxia	1.242673e-6
GO:0006873	cellular ion homeostasis	1.299755e-6
GO:0042221	response to chemical stimulus	1.380696e-6
GO:0014805	smooth muscle adaptation	1.459389e-6
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.489550e-6
GO:0055072	iron ion homeostasis	1.549782e-6
GO:0042993	positive regulation of transcription factor import into nucleus	1.602297e-6
GO:0045087	innate immune response	1.621871e-6
GO:0031667	response to nutrient levels	1.790869e-6
GO:0046907	intracellular transport	1.890345e-6
GO:0043305	negative regulation of mast cell degranulation	2.100582e-6
GO:0045080	positive regulation of chemokine biosynthetic process	2.195824e-6
GO:0010669	epithelial structure maintenance	2.297272e-6
GO:0016044	cellular membrane organization	2.323831e-6
GO:0010038	response to metal ion	2.411050e-6
GO:0060627	regulation of vesicle-mediated transport	2.447103e-6
GO:0050878	regulation of body fluid levels	2.472933e-6
GO:0071260	cellular response to mechanical stimulus	2.477408e-6
GO:0042345	regulation of NF-kappaB import into nucleus	2.613868e-6
GO:0002246	wound healing involved in inflammatory response	2.695874e-6
GO:0046579	positive regulation of Ras protein signal transduction	2.699418e-6
GO:0051297	centrosome organization	2.717660e-6
GO:0061024	membrane organization	2.719062e-6
GO:0023051	regulation of signaling	2.853788e-6
GO:0030728	ovulation	3.062554e-6
GO:0022008	neurogenesis	3.075762e-6
GO:0016049	cell growth	3.082127e-6
GO:0002455	humoral immune response mediated by circulating immunoglobulin	3.136307e-6
GO:0030240	skeletal muscle thin filament assembly	3.197183e-6
GO:0044092	negative regulation of molecular function	3.199300e-6
GO:0048699	generation of neurons	3.319744e-6
GO:0007010	cytoskeleton organization	3.517431e-6
GO:0007399	nervous system development	3.711907e-6
GO:0048468	cell development	3.831558e-6
GO:0006886	intracellular protein transport	4.034822e-6
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	4.099665e-6
GO:0042396	phosphagen biosynthetic process	4.099665e-6
GO:0051704	multi-organism process	4.423724e-6
GO:0000086	G2/M transition of mitotic cell cycle	4.581609e-6
GO:0071241	cellular response to inorganic substance	4.617049e-6
GO:0006928	cellular component movement	4.640607e-6
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	4.715987e-6
GO:0002576	platelet degranulation	4.878774e-6
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	5.074592e-6
GO:0006703	estrogen biosynthetic process	5.152145e-6
GO:0050690	regulation of defense response to virus by virus	5.210923e-6
GO:0050756	fractalkine metabolic process	5.383726e-6
GO:0061370	testosterone biosynthetic process	5.383726e-6
GO:0033595	response to genistein	5.383726e-6
GO:0050778	positive regulation of immune response	5.676913e-6
GO:0019226	transmission of nerve impulse	5.859948e-6
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	5.868516e-6
GO:0002922	positive regulation of humoral immune response	6.005314e-6
GO:0060716	labyrinthine layer blood vessel development	6.152789e-6
GO:0048585	negative regulation of response to stimulus	6.219794e-6
GO:0055082	cellular chemical homeostasis	6.350480e-6
GO:0048584	positive regulation of response to stimulus	6.565194e-6
GO:0051960	regulation of nervous system development	6.773298e-6
GO:0048609	multicellular organismal reproductive process	6.839227e-6
GO:0002579	positive regulation of antigen processing and presentation	7.151846e-6
GO:0046314	phosphocreatine biosynthetic process	7.285162e-6
GO:0002697	regulation of immune effector process	7.421382e-6
GO:0030900	forebrain development	7.424292e-6
GO:0060632	regulation of microtubule-based movement	7.684234e-6
GO:0033036	macromolecule localization	8.225387e-6
GO:0035023	regulation of Rho protein signal transduction	8.986710e-6
GO:0051238	sequestering of metal ion	9.119199e-6
GO:0033273	response to vitamin	9.231883e-6
GO:0045655	regulation of monocyte differentiation	9.385507e-6
GO:2000098	negative regulation of smooth muscle cell-matrix adhesion	9.660224e-6
GO:0071258	cellular response to gravity	9.660224e-6
GO:0035491	positive regulation of leukotriene production involved in inflammatory response	9.660224e-6
GO:0061044	negative regulation of vascular wound healing	9.660224e-6
GO:0090023	positive regulation of neutrophil chemotaxis	1.068806e-5
GO:0002891	positive regulation of immunoglobulin mediated immune response	1.119720e-5
GO:0021756	striatum development	1.121837e-5
GO:0014806	smooth muscle hyperplasia	1.133522e-5
GO:0045657	positive regulation of monocyte differentiation	1.147170e-5
GO:0021983	pituitary gland development	1.169943e-5
GO:0001775	cell activation	1.172741e-5
GO:0043068	positive regulation of programmed cell death	1.182184e-5
GO:0010035	response to inorganic substance	1.241986e-5
GO:0010648	negative regulation of cell communication	1.363390e-5
GO:0002886	regulation of myeloid leukocyte mediated immunity	1.380974e-5
GO:0035270	endocrine system development	1.386795e-5
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	1.429838e-5
GO:0031023	microtubule organizing center organization	1.445655e-5
GO:0023057	negative regulation of signaling	1.453844e-5
GO:0009887	organ morphogenesis	1.568565e-5
GO:0046903	secretion	1.593201e-5
GO:0032757	positive regulation of interleukin-8 production	1.613790e-5
GO:0048520	positive regulation of behavior	1.647065e-5
GO:0014912	negative regulation of smooth muscle cell migration	1.721388e-5
GO:0007268	synaptic transmission	1.735897e-5
GO:0060027	convergent extension involved in gastrulation	1.756396e-5
GO:0031659	positive regulation of cyclin-dependent protein kinase activity involved in G1/S	1.780773e-5
GO:0090222	centrosome-templated microtubule nucleation	1.801105e-5
GO:0072376	protein activation cascade	1.804108e-5
GO:0001893	maternal placenta development	1.820078e-5
GO:0042990	regulation of transcription factor import into nucleus	1.844697e-5
GO:0010226	response to lithium ion	1.886400e-5
GO:0002673	regulation of acute inflammatory response	1.919305e-5
GO:0050688	regulation of defense response to virus	1.950300e-5
GO:0007249	I-kappaB kinase/NF-kappaB cascade	2.010795e-5
GO:2000097	regulation of smooth muscle cell-matrix adhesion	2.022702e-5
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	2.022729e-5
GO:0055002	striated muscle cell development	2.087809e-5
GO:0045785	positive regulation of cell adhesion	2.180612e-5
GO:0010646	regulation of cell communication	2.249634e-5
GO:0046889	positive regulation of lipid biosynthetic process	2.262968e-5
GO:0042940	D-amino acid transport	2.305311e-5
GO:0007267	cell-cell signaling	2.403747e-5
GO:0021536	diencephalon development	2.453087e-5
GO:0051938	L-glutamate import	2.539318e-5
GO:0030834	regulation of actin filament depolymerization	2.572110e-5
GO:0002819	regulation of adaptive immune response	2.592763e-5
GO:0031214	biomineral tissue development	2.605422e-5
GO:0010466	negative regulation of peptidase activity	2.608690e-5
GO:0006880	intracellular sequestering of iron ion	2.622921e-5
GO:0007565	female pregnancy	2.769035e-5
GO:0048519	negative regulation of biological process	2.773434e-5
GO:0006897	endocytosis	2.823698e-5
GO:0007015	actin filament organization	2.830702e-5
GO:0022600	digestive system process	2.885220e-5
GO:0051693	actin filament capping	2.923726e-5
GO:0030835	negative regulation of actin filament depolymerization	2.969420e-5
GO:0010942	positive regulation of cell death	2.977397e-5
GO:0007620	copulation	3.100683e-5
GO:0051345	positive regulation of hydrolase activity	3.205982e-5
GO:0000041	transition metal ion transport	3.330221e-5
GO:0034097	response to cytokine stimulus	3.389286e-5
GO:0009894	regulation of catabolic process	3.437607e-5
GO:0030878	thyroid gland development	3.469627e-5
GO:0044060	regulation of endocrine process	3.474311e-5
GO:0045651	positive regulation of macrophage differentiation	3.504492e-5
GO:0050921	positive regulation of chemotaxis	3.800984e-5
GO:0072507	divalent inorganic cation homeostasis	3.802416e-5
GO:0006826	iron ion transport	3.822792e-5
GO:0021544	subpallium development	3.950811e-5
GO:0007589	body fluid secretion	4.093323e-5
GO:0032764	negative regulation of mast cell cytokine production	4.158640e-5
GO:0032879	regulation of localization	4.279527e-5
GO:0045073	regulation of chemokine biosynthetic process	4.284403e-5
GO:0050801	ion homeostasis	4.296428e-5
GO:0030100	regulation of endocytosis	4.449693e-5
GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis	4.466782e-5
GO:0034764	positive regulation of transmembrane transport	4.553056e-5
GO:0051247	positive regulation of protein metabolic process	4.814848e-5
GO:0022414	reproductive process	4.820957e-5
GO:0055067	monovalent inorganic cation homeostasis	4.846294e-5
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	4.920350e-5
GO:0048871	multicellular organismal homeostasis	5.002669e-5
GO:0007635	chemosensory behavior	5.024925e-5
GO:0002682	regulation of immune system process	5.029004e-5
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	5.037620e-5
GO:0002685	regulation of leukocyte migration	5.157464e-5
GO:0010193	response to ozone	5.240162e-5
GO:0051049	regulation of transport	5.266832e-5
GO:0070741	response to interleukin-6	5.280959e-5
GO:0060611	mammary gland fat development	5.433505e-5
GO:0070727	cellular macromolecule localization	5.566497e-5
GO:0009966	regulation of signal transduction	5.637093e-5
GO:0006778	porphyrin-containing compound metabolic process	5.640064e-5
GO:0042167	heme catabolic process	5.738322e-5
GO:0048666	neuron development	5.855543e-5
GO:0072503	cellular divalent inorganic cation homeostasis	5.874911e-5
GO:0043462	regulation of ATPase activity	5.880560e-5
GO:0033687	osteoblast proliferation	5.939781e-5
GO:0000003	reproduction	5.982540e-5
GO:0019725	cellular homeostasis	6.460667e-5
GO:0002830	positive regulation of type 2 immune response	6.577129e-5
GO:0010811	positive regulation of cell-substrate adhesion	6.673968e-5
GO:0042488	positive regulation of odontogenesis of dentine-containing tooth	6.721954e-5
GO:0033121	regulation of purine nucleotide catabolic process	6.875757e-5
GO:0010033	response to organic substance	7.141180e-5
GO:0090022	regulation of neutrophil chemotaxis	7.240942e-5
GO:0032971	regulation of muscle filament sliding	7.244215e-5
GO:0034613	cellular protein localization	7.309839e-5
GO:0032496	response to lipopolysaccharide	7.335125e-5
GO:0009607	response to biotic stimulus	7.336304e-5
GO:0043085	positive regulation of catalytic activity	7.343941e-5
GO:0007243	intracellular protein kinase cascade	7.410135e-5
GO:0033013	tetrapyrrole metabolic process	7.494787e-5
GO:0009296	flagellum assembly	7.606723e-5
GO:0001300	chronological cell aging	7.821422e-5
GO:0016064	immunoglobulin mediated immune response	7.954355e-5
GO:0048878	chemical homeostasis	7.977688e-5
GO:0043065	positive regulation of apoptosis	8.158919e-5
GO:0002237	response to molecule of bacterial origin	8.246233e-5
GO:0055001	muscle cell development	8.493240e-5
GO:0015810	aspartate transport	8.493515e-5
GO:0031329	regulation of cellular catabolic process	8.580181e-5
GO:0031657	regulation of cyclin-dependent protein kinase activity involved in G1/S	8.701433e-5
GO:0048791	calcium ion-dependent exocytosis of neurotransmitter	8.833214e-5
GO:0009115	xanthine catabolic process	8.833418e-5
GO:0030194	positive regulation of blood coagulation	9.047403e-5
GO:0033617	mitochondrial respiratory chain complex IV assembly	9.301475e-5
GO:0006746	FADH2 metabolic process	9.301475e-5
GO:0032425	positive regulation of mismatch repair	9.767149e-5
GO:0046651	lymphocyte proliferation	9.819214e-5
GO:0032722	positive regulation of chemokine production	9.905757e-5
GO:0045089	positive regulation of innate immune response	1.006091e-4
GO:0050764	regulation of phagocytosis	1.028537e-4
GO:0071731	response to nitric oxide	1.064843e-4
GO:0050920	regulation of chemotaxis	1.089339e-4
GO:0051764	actin crosslink formation	1.095416e-4
GO:0001660	fever generation	1.110521e-4
GO:0070779	D-aspartate import	1.127084e-4
GO:0002861	regulation of inflammatory response to antigenic stimulus	1.139943e-4
GO:0051707	response to other organism	1.168989e-4
GO:0045738	negative regulation of DNA repair	1.169835e-4
GO:0050790	regulation of catalytic activity	1.237973e-4
GO:0032677	regulation of interleukin-8 production	1.248996e-4
GO:0002699	positive regulation of immune effector process	1.274266e-4
GO:0090084	negative regulation of inclusion body assembly	1.290633e-4
GO:0052547	regulation of peptidase activity	1.297332e-4
GO:0019724	B cell mediated immunity	1.305662e-4
GO:0048278	vesicle docking	1.372583e-4
GO:2001020	regulation of response to DNA damage stimulus	1.385315e-4
GO:0015031	protein transport	1.389556e-4
GO:0051222	positive regulation of protein transport	1.392721e-4
GO:0006885	regulation of pH	1.413983e-4
GO:0007599	hemostasis	1.419232e-4
GO:0001542	ovulation from ovarian follicle	1.424268e-4
GO:0030182	neuron differentiation	1.443262e-4
GO:0009968	negative regulation of signal transduction	1.453669e-4
GO:0043217	myelin maintenance	1.478178e-4
GO:0048646	anatomical structure formation involved in morphogenesis	1.553207e-4
GO:0071842	cellular component organization at cellular level	1.604577e-4
GO:0007205	activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway	1.610848e-4
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	1.617354e-4
GO:0045059	positive thymic T cell selection	1.637719e-4
GO:0032386	regulation of intracellular transport	1.648045e-4
GO:0048011	nerve growth factor receptor signaling pathway	1.710677e-4
GO:0043030	regulation of macrophage activation	1.718710e-4
GO:0006887	exocytosis	1.747819e-4
GO:0044245	polysaccharide digestion	1.751229e-4
GO:0051298	centrosome duplication	1.801236e-4
GO:0010740	positive regulation of intracellular protein kinase cascade	1.809836e-4
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.863824e-4
GO:0044258	intestinal lipid catabolic process	1.865208e-4
GO:0018350	protein esterification	1.865208e-4
GO:0007041	lysosomal transport	1.872579e-4
GO:0042663	regulation of endodermal cell fate specification	1.925479e-4
GO:0048266	behavioral response to pain	1.937535e-4
GO:0030193	regulation of blood coagulation	1.992156e-4
GO:0008104	protein localization	1.996974e-4
GO:0051128	regulation of cellular component organization	2.006938e-4
GO:0005993	trehalose catabolic process	2.023048e-4
GO:0043060	meiotic metaphase I plate congression	2.059308e-4
GO:0002920	regulation of humoral immune response	2.141817e-4
GO:0009629	response to gravity	2.157262e-4
GO:0002690	positive regulation of leukocyte chemotaxis	2.177312e-4
GO:0050820	positive regulation of coagulation	2.187412e-4
GO:0015849	organic acid transport	2.222578e-4
GO:0060907	positive regulation of macrophage cytokine production	2.279193e-4
GO:0001504	neurotransmitter uptake	2.306112e-4
GO:0051930	regulation of sensory perception of pain	2.309354e-4
GO:0051146	striated muscle cell differentiation	2.341749e-4
GO:0045184	establishment of protein localization	2.346607e-4
GO:0032943	mononuclear cell proliferation	2.360933e-4
GO:0045070	positive regulation of viral genome replication	2.366867e-4
GO:0007596	blood coagulation	2.386709e-4
GO:0006828	manganese ion transport	2.411687e-4
GO:0014047	glutamate secretion	2.528845e-4
GO:0046942	carboxylic acid transport	2.618700e-4
GO:0009826	unidimensional cell growth	2.624070e-4
GO:0030216	keratinocyte differentiation	2.638982e-4
GO:0010867	positive regulation of triglyceride biosynthetic process	2.642091e-4
GO:0060879	semicircular canal fusion	2.674350e-4
GO:0070352	positive regulation of white fat cell proliferation	2.674350e-4
GO:0060661	submandibular salivary gland formation	2.674350e-4
GO:0061115	lung proximal/distal axis specification	2.674350e-4
GO:0050674	urothelial cell proliferation	2.674350e-4
GO:0060496	mesenchymal-epithelial cell signaling involved in lung development	2.674350e-4
GO:0050677	positive regulation of urothelial cell proliferation	2.674350e-4
GO:0060436	bronchiole morphogenesis	2.674350e-4
GO:0006874	cellular calcium ion homeostasis	2.719489e-4
GO:0042137	sequestering of neurotransmitter	2.726172e-4
GO:0070668	positive regulation of mast cell proliferation	2.800087e-4
GO:0002502	peptide antigen assembly with MHC class I protein complex	2.800175e-4
GO:0034454	microtubule anchoring at centrosome	2.867268e-4
GO:0070661	leukocyte proliferation	2.886204e-4
GO:0007286	spermatid development	3.009287e-4
GO:0050776	regulation of immune response	3.230305e-4
GO:0031424	keratinization	3.255321e-4
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	3.255851e-4
GO:0061041	regulation of wound healing	3.299098e-4
GO:0018904	organic ether metabolic process	3.300897e-4
GO:0050877	neurological system process	3.320023e-4
GO:0018894	dibenzo-p-dioxin metabolic process	3.361660e-4
GO:0002718	regulation of cytokine production involved in immune response	3.368169e-4
GO:0033025	regulation of mast cell apoptosis	3.406444e-4
GO:0032989	cellular component morphogenesis	3.541361e-4
GO:0002577	regulation of antigen processing and presentation	3.549044e-4
GO:0007017	microtubule-based process	3.582328e-4
GO:0032320	positive regulation of Ras GTPase activity	3.754043e-4
GO:0003018	vascular process in circulatory system	3.806045e-4
GO:0071841	cellular component organization or biogenesis at cellular level	3.842409e-4
GO:0051918	negative regulation of fibrinolysis	3.865086e-4
GO:0002687	positive regulation of leukocyte migration	3.911732e-4
GO:0052548	regulation of endopeptidase activity	3.971224e-4
GO:0048523	negative regulation of cellular process	4.081441e-4
GO:0000132	establishment of mitotic spindle orientation	4.082310e-4
GO:0048515	spermatid differentiation	4.102174e-4
GO:0006904	vesicle docking involved in exocytosis	4.250082e-4
GO:0044093	positive regulation of molecular function	4.440051e-4
GO:0030030	cell projection organization	4.461527e-4
GO:0051409	response to nitrosative stress	4.485046e-4
GO:0002260	lymphocyte homeostasis	4.576466e-4
GO:0001776	leukocyte homeostasis	4.612290e-4
GO:0009744	response to sucrose stimulus	4.624504e-4
GO:0031958	corticosteroid receptor signaling pathway	4.643754e-4
GO:0032741	positive regulation of interleukin-18 production	4.651797e-4
GO:0048667	cell morphogenesis involved in neuron differentiation	4.686587e-4
GO:0007420	brain development	4.690757e-4
GO:0007409	axonogenesis	4.726778e-4
GO:0048146	positive regulation of fibroblast proliferation	4.732525e-4
GO:0002684	positive regulation of immune system process	4.763233e-4
GO:0048812	neuron projection morphogenesis	4.767080e-4
GO:0022406	membrane docking	4.813772e-4
GO:0051329	interphase of mitotic cell cycle	4.837522e-4
GO:0019884	antigen processing and presentation of exogenous antigen	4.888610e-4
GO:0070372	regulation of ERK1 and ERK2 cascade	4.907791e-4
GO:0050880	regulation of blood vessel size	4.914410e-4
GO:0030837	negative regulation of actin filament polymerization	5.050907e-4
GO:0060136	embryonic process involved in female pregnancy	5.134303e-4
GO:0009725	response to hormone stimulus	5.158981e-4
GO:0006140	regulation of nucleotide metabolic process	5.229148e-4
GO:0048872	homeostasis of number of cells	5.286999e-4
GO:0006892	post-Golgi vesicle-mediated transport	5.430934e-4
GO:0055074	calcium ion homeostasis	5.460665e-4
GO:0001894	tissue homeostasis	5.509344e-4
GO:0002889	regulation of immunoglobulin mediated immune response	5.667921e-4
GO:0040001	establishment of mitotic spindle localization	5.770596e-4
GO:0035150	regulation of tube size	5.827471e-4
GO:0007042	lysosomal lumen acidification	5.910852e-4
GO:2000036	regulation of stem cell maintenance	6.286125e-4
GO:0050795	regulation of behavior	6.397403e-4
GO:0090066	regulation of anatomical structure size	6.403806e-4
GO:0030316	osteoclast differentiation	6.439613e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0050896	response to stimulus	2.180054e-20
GO:0065008	regulation of biological quality	7.733806e-14
GO:0045672	positive regulation of osteoclast differentiation	2.133927e-13
GO:0051716	cellular response to stimulus	3.180201e-13
GO:0007154	cell communication	4.204435e-13
GO:0042221	response to chemical stimulus	5.155989e-13
GO:0065007	biological regulation	8.525925e-13
GO:0023052	signaling	9.494822e-13
GO:0048731	system development	1.131597e-12
GO:0045639	positive regulation of myeloid cell differentiation	1.659360e-12
GO:0048856	anatomical structure development	7.855710e-12
GO:0032501	multicellular organismal process	8.213241e-12
GO:0015670	carbon dioxide transport	1.050291e-11
GO:0048513	organ development	1.416918e-11
GO:0015669	gas transport	2.733261e-11
GO:0007165	signal transduction	4.267097e-11
GO:0045124	regulation of bone resorption	7.889494e-11
GO:0002763	positive regulation of myeloid leukocyte differentiation	8.195651e-11
GO:0003008	system process	9.682123e-11
GO:0034103	regulation of tissue remodeling	1.499002e-10
GO:0046850	regulation of bone remodeling	2.003878e-10
GO:0072595	maintenance of protein localization to organelle	2.214113e-10
GO:0010035	response to inorganic substance	2.547645e-10
GO:0051457	maintenance of protein location in nucleus	3.078181e-10
GO:0032849	positive regulation of cellular pH reduction	4.332665e-10
GO:0043503	skeletal muscle fiber adaptation	4.717077e-10
GO:0007275	multicellular organismal development	4.808999e-10
GO:0006950	response to stress	5.028979e-10
GO:0002682	regulation of immune system process	7.137731e-10
GO:0030097	hemopoiesis	1.090379e-9
GO:0050789	regulation of biological process	1.116101e-9
GO:0042592	homeostatic process	1.291841e-9
GO:0048534	hemopoietic or lymphoid organ development	2.703289e-9
GO:0045780	positive regulation of bone resorption	3.411995e-9
GO:0060013	righting reflex	6.828137e-9
GO:0010038	response to metal ion	7.244951e-9
GO:0014866	skeletal myofibril assembly	7.251738e-9
GO:0032502	developmental process	7.823341e-9
GO:0040032	post-embryonic body morphogenesis	8.622194e-9
GO:0055001	muscle cell development	1.000351e-8
GO:0002520	immune system development	1.293141e-8
GO:0060004	reflex	1.444480e-8
GO:0034105	positive regulation of tissue remodeling	1.975411e-8
GO:2000249	regulation of actin cytoskeleton reorganization	2.363743e-8
GO:0002376	immune system process	2.388668e-8
GO:0045637	regulation of myeloid cell differentiation	2.454618e-8
GO:0050907	detection of chemical stimulus involved in sensory perception	2.494376e-8
GO:0007606	sensory perception of chemical stimulus	3.076005e-8
GO:0051239	regulation of multicellular organismal process	3.533769e-8
GO:0051023	regulation of immunoglobulin secretion	4.577528e-8
GO:0050877	neurological system process	4.962379e-8
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	5.693553e-8
GO:0030240	skeletal muscle thin filament assembly	9.032812e-8
GO:0040007	growth	1.012477e-7
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	1.059784e-7
GO:0046967	cytosol to ER transport	1.437164e-7
GO:0019060	intracellular transport of viral proteins in host cell	1.437164e-7
GO:0050794	regulation of cellular process	1.486403e-7
GO:0001894	tissue homeostasis	1.758345e-7
GO:0032507	maintenance of protein location in cell	2.124314e-7
GO:0021758	putamen development	2.698932e-7
GO:0021757	caudate nucleus development	2.698932e-7
GO:0003012	muscle system process	3.727041e-7
GO:0060292	long term synaptic depression	3.836210e-7
GO:0050801	ion homeostasis	3.920209e-7
GO:0032847	regulation of cellular pH reduction	4.123597e-7
GO:0046649	lymphocyte activation	5.119882e-7
GO:0015980	energy derivation by oxidation of organic compounds	5.675918e-7
GO:0002064	epithelial cell development	5.827620e-7
GO:0070887	cellular response to chemical stimulus	6.466098e-7
GO:0019725	cellular homeostasis	6.562034e-7
GO:2000351	regulation of endothelial cell apoptosis	7.371189e-7
GO:0007423	sensory organ development	7.559504e-7
GO:0055013	cardiac muscle cell development	8.268988e-7
GO:0030239	myofibril assembly	8.917367e-7
GO:0090183	regulation of kidney development	9.764741e-7
GO:0042573	retinoic acid metabolic process	1.052781e-6
GO:0009404	toxin metabolic process	1.187465e-6
GO:0009886	post-embryonic morphogenesis	1.251306e-6
GO:0009593	detection of chemical stimulus	1.279201e-6
GO:0006730	one-carbon metabolic process	1.296197e-6
GO:0050906	detection of stimulus involved in sensory perception	1.464823e-6
GO:0048878	chemical homeostasis	1.581118e-6
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	1.919267e-6
GO:0034614	cellular response to reactive oxygen species	1.921735e-6
GO:0007186	G-protein coupled receptor protein signaling pathway	1.967959e-6
GO:0051235	maintenance of location	1.995685e-6
GO:0051651	maintenance of location in cell	2.053085e-6
GO:0045185	maintenance of protein location	2.198920e-6
GO:0055006	cardiac cell development	2.252621e-6
GO:0051146	striated muscle cell differentiation	2.334388e-6
GO:0072273	metanephric nephron morphogenesis	2.392072e-6
GO:0001833	inner cell mass cell proliferation	2.395085e-6
GO:2000353	positive regulation of endothelial cell apoptosis	2.675346e-6
GO:0070301	cellular response to hydrogen peroxide	2.728743e-6
GO:0031032	actomyosin structure organization	2.979758e-6
GO:0042692	muscle cell differentiation	3.117547e-6
GO:2000027	regulation of organ morphogenesis	3.119149e-6
GO:0000302	response to reactive oxygen species	3.416556e-6
GO:0048871	multicellular organismal homeostasis	3.578636e-6
GO:0006112	energy reserve metabolic process	3.850279e-6
GO:0045722	positive regulation of gluconeogenesis	4.073883e-6
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	4.235462e-6
GO:0006873	cellular ion homeostasis	4.281359e-6
GO:0048869	cellular developmental process	4.589314e-6
GO:0045321	leukocyte activation	4.624807e-6
GO:0001832	blastocyst growth	4.838594e-6
GO:0034653	retinoic acid catabolic process	5.286416e-6
GO:0010033	response to organic substance	5.332634e-6
GO:0072088	nephron epithelium morphogenesis	5.373721e-6
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	5.635365e-6
GO:0055002	striated muscle cell development	5.886027e-6
GO:0014706	striated muscle tissue development	6.355907e-6
GO:0060249	anatomical structure homeostasis	6.556980e-6
GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	6.685242e-6
GO:0071874	cellular response to norepinephrine stimulus	7.490117e-6
GO:0042475	odontogenesis of dentine-containing tooth	8.335936e-6
GO:0002761	regulation of myeloid leukocyte differentiation	8.359817e-6
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	8.564657e-6
GO:0030154	cell differentiation	8.777529e-6
GO:0032414	positive regulation of ion transmembrane transporter activity	8.841650e-6
GO:0055082	cellular chemical homeostasis	8.940163e-6
GO:0006936	muscle contraction	9.434130e-6
GO:0032853	positive regulation of Ran GTPase activity	9.738068e-6
GO:0009229	thiamine diphosphate biosynthetic process	9.738068e-6
GO:0072040	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis	1.018275e-5
GO:0051939	gamma-aminobutyric acid import	1.067136e-5
GO:0031124	mRNA 3'-end processing	1.142390e-5
GO:0032259	methylation	1.192068e-5
GO:0050793	regulation of developmental process	1.261970e-5
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	1.285807e-5
GO:0072289	metanephric nephron tubule formation	1.328382e-5
GO:0031123	RNA 3'-end processing	1.359440e-5
GO:0006776	vitamin A metabolic process	1.461239e-5
GO:0048747	muscle fiber development	1.467332e-5
GO:0072077	renal vesicle morphogenesis	1.569841e-5
GO:0051240	positive regulation of multicellular organismal process	1.770352e-5
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	1.800598e-5
GO:0043501	skeletal muscle adaptation	1.847610e-5
GO:0035264	multicellular organism growth	2.208235e-5
GO:0010715	regulation of extracellular matrix disassembly	2.218879e-5
GO:0007600	sensory perception	2.224636e-5
GO:0042110	T cell activation	2.432724e-5
GO:0017085	response to insecticide	2.464516e-5
GO:0001778	plasma membrane repair	2.521164e-5
GO:0043010	camera-type eye development	2.548543e-5
GO:0051179	localization	2.729290e-5
GO:0048741	skeletal muscle fiber development	2.809730e-5
GO:0001508	regulation of action potential	2.864710e-5
GO:0003382	epithelial cell morphogenesis	2.875395e-5
GO:0009719	response to endogenous stimulus	2.895714e-5
GO:0009611	response to wounding	3.270551e-5
GO:0042402	cellular biogenic amine catabolic process	3.331512e-5
GO:0050776	regulation of immune response	3.395374e-5
GO:0019226	transmission of nerve impulse	3.667627e-5
GO:0060347	heart trabecula formation	3.671356e-5
GO:0007166	cell surface receptor linked signaling pathway	3.679370e-5
GO:0060537	muscle tissue development	3.737654e-5
GO:0001654	eye development	4.003162e-5
GO:0045589	regulation of regulatory T cell differentiation	4.045776e-5
GO:0006979	response to oxidative stress	4.277425e-5
GO:0045670	regulation of osteoclast differentiation	4.336495e-5
GO:0051606	detection of stimulus	4.400003e-5
GO:0042363	fat-soluble vitamin catabolic process	4.614641e-5
GO:0070371	ERK1 and ERK2 cascade	4.626679e-5
GO:0010259	multicellular organismal aging	4.776292e-5
GO:0002521	leukocyte differentiation	4.811109e-5
GO:0009628	response to abiotic stimulus	4.845638e-5
GO:0072028	nephron morphogenesis	4.877221e-5
GO:0019362	pyridine nucleotide metabolic process	4.914598e-5
GO:0006970	response to osmotic stress	4.930971e-5
GO:0046037	GMP metabolic process	5.230281e-5
GO:0002637	regulation of immunoglobulin production	5.231260e-5
GO:0009791	post-embryonic development	5.554482e-5
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	5.714337e-5
GO:0055003	cardiac myofibril assembly	5.976417e-5
GO:0072282	metanephric nephron tubule morphogenesis	6.111671e-5
GO:0010735	positive regulation of transcription via serum response element binding	6.174001e-5
GO:0072215	regulation of metanephros development	6.700018e-5
GO:0007608	sensory perception of smell	6.739829e-5
GO:0001823	mesonephros development	6.809864e-5
GO:0009605	response to external stimulus	6.825835e-5
GO:0007399	nervous system development	6.865504e-5
GO:0001783	B cell apoptosis	7.091775e-5
GO:0014816	satellite cell differentiation	7.347461e-5
GO:0002312	B cell activation involved in immune response	7.649808e-5
GO:0055080	cation homeostasis	7.722071e-5
GO:0051234	establishment of localization	7.744283e-5
GO:0019556	histidine catabolic process to glutamate and formamide	7.797212e-5
GO:0006378	mRNA polyadenylation	7.833450e-5
GO:0001523	retinoid metabolic process	8.142228e-5
GO:0032088	negative regulation of NF-kappaB transcription factor activity	8.576845e-5
GO:0018345	protein palmitoylation	8.599839e-5
GO:0009887	organ morphogenesis	8.661498e-5
GO:0034599	cellular response to oxidative stress	9.003672e-5
GO:0043269	regulation of ion transport	9.478689e-5
GO:0045348	positive regulation of MHC class II biosynthetic process	9.701027e-5
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	1.000304e-4
GO:0030048	actin filament-based movement	1.046195e-4
GO:0048754	branching morphogenesis of a tube	1.057098e-4
GO:0051056	regulation of small GTPase mediated signal transduction	1.078779e-4
GO:0002709	regulation of T cell mediated immunity	1.125608e-4
GO:0051704	multi-organism process	1.141942e-4
GO:0048518	positive regulation of biological process	1.147775e-4
GO:0072210	metanephric nephron development	1.153671e-4
GO:0009725	response to hormone stimulus	1.159078e-4
GO:0043067	regulation of programmed cell death	1.159422e-4
GO:0046653	tetrahydrofolate metabolic process	1.206170e-4
GO:0019441	tryptophan catabolic process to kynurenine	1.207788e-4
GO:0009888	tissue development	1.215458e-4
GO:0060231	mesenchymal to epithelial transition	1.219816e-4
GO:0042743	hydrogen peroxide metabolic process	1.240884e-4
GO:0046483	heterocycle metabolic process	1.255086e-4
GO:0042297	vocal learning	1.317753e-4
GO:0046496	nicotinamide nucleotide metabolic process	1.319548e-4
GO:0002837	regulation of immune response to tumor cell	1.323385e-4
GO:0072283	metanephric renal vesicle morphogenesis	1.326987e-4
GO:0080164	regulation of nitric oxide metabolic process	1.329392e-4
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway	1.366772e-4
GO:0051252	regulation of RNA metabolic process	1.423312e-4
GO:0002318	myeloid progenitor cell differentiation	1.427971e-4
GO:0045590	negative regulation of regulatory T cell differentiation	1.440732e-4
GO:0042060	wound healing	1.446284e-4
GO:0001824	blastocyst development	1.451560e-4
GO:0042744	hydrogen peroxide catabolic process	1.513246e-4
GO:0031334	positive regulation of protein complex assembly	1.594411e-4
GO:0061061	muscle structure development	1.639889e-4
GO:0071870	cellular response to catecholamine stimulus	1.664539e-4
GO:0035590	purinergic nucleotide receptor signaling pathway	1.672108e-4
GO:0042445	hormone metabolic process	1.674617e-4
GO:0046684	response to pyrethroid	1.696432e-4
GO:0022600	digestive system process	1.701760e-4
GO:0007610	behavior	1.710899e-4
GO:0072592	oxygen metabolic process	1.749602e-4
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	1.749602e-4
GO:2000026	regulation of multicellular organismal development	1.785332e-4
GO:0003338	metanephros morphogenesis	1.797391e-4
GO:0035051	cardiac cell differentiation	1.815100e-4
GO:0072034	renal vesicle induction	1.821401e-4
GO:0045764	positive regulation of cellular amino acid metabolic process	1.902655e-4
GO:0043092	L-amino acid import	1.943434e-4
GO:0010043	response to zinc ion	1.954119e-4
GO:0050808	synapse organization	1.957824e-4
GO:0055007	cardiac muscle cell differentiation	1.967106e-4
GO:0042981	regulation of apoptosis	1.988778e-4
GO:0030098	lymphocyte differentiation	2.033398e-4
GO:0009743	response to carbohydrate stimulus	2.055609e-4
GO:0035247	peptidyl-arginine omega-N-methylation	2.102501e-4
GO:0060005	vestibular reflex	2.105106e-4
GO:0010225	response to UV-C	2.132004e-4
GO:0007009	plasma membrane organization	2.162812e-4
GO:0002026	regulation of the force of heart contraction	2.164434e-4
GO:0002839	positive regulation of immune response to tumor cell	2.267842e-4
GO:0002833	positive regulation of response to biotic stimulus	2.323249e-4
GO:0018094	protein polyglycylation	2.369434e-4
GO:0001887	selenium compound metabolic process	2.369434e-4
GO:0043462	regulation of ATPase activity	2.378664e-4
GO:0019439	aromatic compound catabolic process	2.382424e-4
GO:0060047	heart contraction	2.403182e-4
GO:0051024	positive regulation of immunoglobulin secretion	2.406128e-4
GO:0007601	visual perception	2.409822e-4
GO:0006805	xenobiotic metabolic process	2.468430e-4
GO:0030818	negative regulation of cAMP biosynthetic process	2.539676e-4
GO:0022603	regulation of anatomical structure morphogenesis	2.557069e-4
GO:0048738	cardiac muscle tissue development	2.578459e-4
GO:0072087	renal vesicle development	2.590092e-4
GO:0001775	cell activation	2.678347e-4
GO:0035886	vascular smooth muscle cell differentiation	2.720293e-4
GO:0018364	peptidyl-glutamine methylation	2.840394e-4
GO:0009612	response to mechanical stimulus	2.861584e-4
GO:0030099	myeloid cell differentiation	2.886202e-4
GO:0070995	NADPH oxidation	2.926647e-4
GO:0019227	neuronal action potential propagation	2.965554e-4
GO:0097035	regulation of membrane lipid distribution	2.965554e-4
GO:0032411	positive regulation of transporter activity	2.965803e-4
GO:0009410	response to xenobiotic stimulus	2.994417e-4
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	3.084981e-4
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	3.144096e-4
GO:0048489	synaptic vesicle transport	3.212368e-4
GO:0016101	diterpenoid metabolic process	3.220650e-4
GO:0021658	rhombomere 3 morphogenesis	3.261587e-4
GO:0019228	regulation of action potential in neuron	3.401663e-4
GO:0008366	axon ensheathment	3.407527e-4
GO:0050953	sensory perception of light stimulus	3.517599e-4
GO:0021544	subpallium development	3.522675e-4
GO:0043631	RNA polyadenylation	3.562615e-4
GO:0030003	cellular cation homeostasis	3.610154e-4
GO:0006479	protein methylation	3.678809e-4
GO:0042542	response to hydrogen peroxide	3.688063e-4
GO:0006810	transport	3.783853e-4
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	3.926163e-4
GO:0050778	positive regulation of immune response	3.927584e-4
GO:0009749	response to glucose stimulus	3.964095e-4
GO:0072078	nephron tubule morphogenesis	3.992572e-4
GO:0002684	positive regulation of immune system process	4.025893e-4
GO:0042098	T cell proliferation	4.045332e-4
GO:0031943	regulation of glucocorticoid metabolic process	4.059582e-4
GO:0070189	kynurenine metabolic process	4.069252e-4
GO:0042552	myelination	4.081666e-4
GO:0007565	female pregnancy	4.086125e-4
GO:0048469	cell maturation	4.157330e-4
GO:0000041	transition metal ion transport	4.265243e-4
GO:0042551	neuron maturation	4.310494e-4
GO:0008356	asymmetric cell division	4.320657e-4
GO:0071310	cellular response to organic substance	4.462121e-4
GO:0006420	arginyl-tRNA aminoacylation	4.463834e-4
GO:0034284	response to monosaccharide stimulus	4.470110e-4
GO:0010556	regulation of macromolecule biosynthetic process	4.632854e-4
GO:0010468	regulation of gene expression	4.661652e-4
GO:0070555	response to interleukin-1	4.685290e-4
GO:0006355	regulation of transcription, DNA-dependent	4.692768e-4
GO:0048545	response to steroid hormone stimulus	4.791752e-4
GO:0031946	regulation of glucocorticoid biosynthetic process	4.821954e-4
GO:0048793	pronephros development	4.821954e-4
GO:0010949	negative regulation of intestinal phytosterol absorption	4.831600e-4
GO:0045796	negative regulation of intestinal cholesterol absorption	4.831600e-4
GO:0003278	apoptosis involved in heart morphogenesis	4.831600e-4
GO:0010226	response to lithium ion	4.955587e-4
GO:0071320	cellular response to cAMP	5.151982e-4
GO:0045851	pH reduction	5.226356e-4
GO:0072001	renal system development	5.306736e-4
GO:0051171	regulation of nitrogen compound metabolic process	5.463151e-4
GO:0043497	regulation of protein heterodimerization activity	5.504869e-4
GO:0009636	response to toxin	5.855471e-4
GO:0016049	cell growth	5.915107e-4
GO:0055017	cardiac muscle tissue growth	5.920251e-4
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	6.038595e-4
GO:0051977	lysophospholipid transport	6.038595e-4
GO:0001966	thigmotaxis	6.038595e-4
GO:0007630	jump response	6.038595e-4
GO:0070925	organelle assembly	6.204776e-4
GO:2000145	regulation of cell motility	6.398215e-4
GO:0043090	amino acid import	6.434565e-4
GO:0030316	osteoclast differentiation	6.691234e-4
GO:0010172	embryonic body morphogenesis	6.704117e-4
GO:0071347	cellular response to interleukin-1	6.857973e-4
GO:0061036	positive regulation of cartilage development	6.900310e-4
GO:0030855	epithelial cell differentiation	6.909398e-4
GO:0072182	regulation of nephron tubule epithelial cell differentiation	7.106717e-4
GO:0009161	ribonucleoside monophosphate metabolic process	7.240734e-4
GO:0031223	auditory behavior	7.329448e-4
GO:0043500	muscle adaptation	7.641954e-4
GO:0051452	intracellular pH reduction	7.746127e-4
GO:0003334	keratinocyte development	7.764818e-4
GO:0090096	positive regulation of metanephric cap mesenchymal cell proliferation	7.779965e-4
GO:0032861	activation of Rap GTPase activity	7.779965e-4
GO:0090346	cellular organofluorine metabolic process	7.794041e-4
GO:0043602	nitrate catabolic process	7.794041e-4
GO:0046210	nitric oxide catabolic process	7.794041e-4
GO:0071670	smooth muscle cell chemotaxis	7.959377e-4
GO:0060981	cell migration involved in coronary angiogenesis	7.959377e-4
GO:0006772	thiamine metabolic process	7.959377e-4
GO:0051725	protein de-ADP-ribosylation	7.959377e-4
GO:0060554	induction of necroptosis of activated-T cells	7.959377e-4
GO:0032229	negative regulation of synaptic transmission, GABAergic	7.978162e-4
GO:0010941	regulation of cell death	8.171200e-4
GO:0006390	transcription from mitochondrial promoter	8.316448e-4
GO:0061384	heart trabecular morphogenesis	8.332726e-4
GO:0045980	negative regulation of nucleotide metabolic process	8.332726e-4
GO:0021756	striatum development	8.463175e-4
GO:0009123	nucleoside monophosphate metabolic process	8.531660e-4
GO:0043583	ear development	8.681507e-4
GO:0006111	regulation of gluconeogenesis	8.693155e-4
GO:0072079	nephron tubule formation	8.693155e-4
GO:0035587	purinergic receptor signaling pathway	8.958406e-4
GO:0071322	cellular response to carbohydrate stimulus	8.960313e-4
GO:0035855	megakaryocyte development	9.048506e-4
GO:0030334	regulation of cell migration	9.138276e-4
GO:0043414	macromolecule methylation	9.554881e-4
GO:0035588	G-protein coupled purinergic receptor signaling pathway	9.570349e-4
GO:0006568	tryptophan metabolic process	9.599004e-4
GO:0032989	cellular component morphogenesis	9.619214e-4
GO:0051591	response to cAMP	9.619972e-4
GO:0019219	regulation of nucleobase-containing compound metabolic process	9.627280e-4
GO:0006775	fat-soluble vitamin metabolic process	9.672816e-4
GO:0006721	terpenoid metabolic process	9.950185e-4
GO:0034765	regulation of ion transmembrane transport	1.004089e-3
GO:0006733	oxidoreduction coenzyme metabolic process	1.005174e-3
GO:0045085	negative regulation of interleukin-2 biosynthetic process	1.012485e-3
GO:0060675	ureteric bud morphogenesis	1.030436e-3
GO:0009746	response to hexose stimulus	1.055060e-3
GO:0021537	telencephalon development	1.059102e-3
GO:2000142	regulation of transcription initiation, DNA-dependent	1.062773e-3
GO:0032781	positive regulation of ATPase activity	1.065299e-3
GO:0055014	atrial cardiac muscle cell development	1.068156e-3
GO:0072305	negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis	1.070783e-3
GO:2000594	positive regulation of metanephric DCT cell differentiation	1.070783e-3
GO:0039003	pronephric field specification	1.070783e-3
GO:0072593	reactive oxygen species metabolic process	1.073740e-3
GO:2000112	regulation of cellular macromolecule biosynthetic process	1.088292e-3
GO:0060419	heart growth	1.111997e-3
GO:0046651	lymphocyte proliferation	1.125809e-3
GO:0008284	positive regulation of cell proliferation	1.139287e-3
GO:0045542	positive regulation of cholesterol biosynthetic process	1.148724e-3
GO:0032715	negative regulation of interleukin-6 production	1.149331e-3
GO:0051929	positive regulation of calcium ion transport via voltage-gated calcium channel activity	1.153032e-3
GO:0015671	oxygen transport	1.161385e-3
GO:0090184	positive regulation of kidney development	1.175442e-3
GO:0001922	B-1 B cell homeostasis	1.176535e-3
GO:0031645	negative regulation of neurological system process	1.198889e-3
GO:0090292	nuclear matrix anchoring at nuclear membrane	1.202515e-3
GO:0006994	positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway	1.202515e-3
GO:0032957	inositol trisphosphate metabolic process	1.212738e-3
GO:0006811	ion transport	1.219965e-3
GO:0003015	heart process	1.223625e-3
GO:2000612	regulation of thyroid-stimulating hormone secretion	1.238178e-3
GO:0032802	low-density lipoprotein particle receptor catabolic process	1.238187e-3
GO:0055065	metal ion homeostasis	1.275925e-3
GO:0019748	secondary metabolic process	1.295783e-3
GO:0071400	cellular response to oleic acid	1.302314e-3
GO:0006941	striated muscle contraction	1.302663e-3
GO:0001656	metanephros development	1.337577e-3
GO:0072134	nephrogenic mesenchyme morphogenesis	1.343964e-3
GO:2000108	positive regulation of leukocyte apoptosis	1.355342e-3
GO:0008360	regulation of cell shape	1.355862e-3
GO:0051970	negative regulation of transmission of nerve impulse	1.358485e-3
GO:0006739	NADP metabolic process	1.361406e-3
GO:0060048	cardiac muscle contraction	1.362411e-3
GO:0001569	patterning of blood vessels	1.377277e-3
GO:0006548	histidine catabolic process	1.381434e-3
GO:0006621	protein retention in ER lumen	1.382152e-3
GO:0035725	sodium ion transmembrane transport	1.405385e-3
GO:0042135	neurotransmitter catabolic process	1.414119e-3
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	1.420673e-3
GO:0048468	cell development	1.435597e-3
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	1.439025e-3
GO:0022610	biological adhesion	1.452656e-3
GO:0072003	kidney rudiment formation	1.454255e-3
GO:0045602	negative regulation of endothelial cell differentiation	1.454255e-3
GO:0046700	heterocycle catabolic process	1.460594e-3
GO:0042424	catecholamine catabolic process	1.470695e-3
GO:0009074	aromatic amino acid family catabolic process	1.562563e-3
GO:0010288	response to lead ion	1.564537e-3
GO:0044281	small molecule metabolic process	1.565683e-3
GO:0007155	cell adhesion	1.593178e-3
GO:0045766	positive regulation of angiogenesis	1.637191e-3
GO:0035246	peptidyl-arginine N-methylation	1.637192e-3
GO:0032870	cellular response to hormone stimulus	1.648363e-3
GO:0009653	anatomical structure morphogenesis	1.650053e-3
GO:0046578	regulation of Ras protein signal transduction	1.656607e-3
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	1.666878e-3
GO:0000027	ribosomal large subunit assembly	1.666878e-3
GO:0071364	cellular response to epidermal growth factor stimulus	1.705311e-3
GO:0010959	regulation of metal ion transport	1.707615e-3
GO:0061138	morphogenesis of a branching epithelium	1.733791e-3
GO:0001822	kidney development	1.749023e-3
GO:0006766	vitamin metabolic process	1.786489e-3
GO:0030277	maintenance of gastrointestinal epithelium	1.824308e-3
GO:0070661	leukocyte proliferation	1.845926e-3
GO:0034754	cellular hormone metabolic process	1.861034e-3
GO:0042904	9-cis-retinoic acid biosynthetic process	1.870445e-3
GO:0001916	positive regulation of T cell mediated cytotoxicity	1.874028e-3
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	1.889799e-3
GO:0045787	positive regulation of cell cycle	1.900750e-3
GO:0007042	lysosomal lumen acidification	1.926401e-3
GO:0050805	negative regulation of synaptic transmission	1.929578e-3
GO:0071495	cellular response to endogenous stimulus	1.936255e-3
GO:0006603	phosphocreatine metabolic process	1.940698e-3
GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus	1.940698e-3
GO:0045046	protein import into peroxisome membrane	1.953859e-3
GO:0032854	positive regulation of Rap GTPase activity	1.966328e-3
GO:0006875	cellular metal ion homeostasis	1.966343e-3
GO:0060993	kidney morphogenesis	1.967581e-3
GO:0060055	angiogenesis involved in wound healing	1.970117e-3
GO:0032892	positive regulation of organic acid transport	1.970117e-3
GO:0018195	peptidyl-arginine modification	1.970117e-3
GO:0048569	post-embryonic organ development	1.994193e-3
GO:0000045	autophagic vacuole assembly	2.007431e-3
GO:0032943	mononuclear cell proliferation	2.024157e-3
GO:0014037	Schwann cell differentiation	2.051863e-3
GO:0051928	positive regulation of calcium ion transport	2.063984e-3
GO:0048821	erythrocyte development	2.076573e-3
GO:0007588	excretion	2.120965e-3
GO:0048522	positive regulation of cellular process	2.152341e-3
GO:0070830	tight junction assembly	2.156810e-3
GO:0072507	divalent inorganic cation homeostasis	2.198141e-3
GO:0033601	positive regulation of mammary gland epithelial cell proliferation	2.250848e-3
GO:0034633	retinol transport	2.257378e-3
GO:0002551	mast cell chemotaxis	2.257378e-3
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	2.258326e-3
GO:0018216	peptidyl-arginine methylation	2.266514e-3
GO:0045947	negative regulation of translational initiation	2.274542e-3
GO:0006807	nitrogen compound metabolic process	2.282357e-3
GO:0032733	positive regulation of interleukin-10 production	2.304041e-3
GO:0035556	intracellular signal transduction	2.313620e-3
GO:0009889	regulation of biosynthetic process	2.313845e-3
GO:0032703	negative regulation of interleukin-2 production	2.326065e-3
GO:0006547	histidine metabolic process	2.328308e-3
GO:0002483	antigen processing and presentation of endogenous peptide antigen	2.328308e-3
GO:0051270	regulation of cellular component movement	2.328581e-3
GO:0070207	protein homotrimerization	2.334683e-3
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	2.334688e-3
GO:0009651	response to salt stress	2.341225e-3
GO:0008633	activation of pro-apoptotic gene products	2.343360e-3
GO:2000347	positive regulation of hepatocyte proliferation	2.355339e-3
GO:0043401	steroid hormone mediated signaling pathway	2.363232e-3
GO:0071383	cellular response to steroid hormone stimulus	2.370857e-3
GO:0031326	regulation of cellular biosynthetic process	2.483472e-3
GO:0014888	striated muscle adaptation	2.489702e-3
GO:0048593	camera-type eye morphogenesis	2.523412e-3