Novel motif:144

name:	motif144_AAKCMSGT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0052572	response to host immune response	2.843080e-12
GO:0002281	macrophage activation involved in immune response	8.814760e-9
GO:0060764	cell-cell signaling involved in mammary gland development	2.167263e-8
GO:0006741	NADP biosynthetic process	5.375530e-8
GO:0002282	microglial cell activation involved in immune response	5.654206e-8
GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity	9.434578e-8
GO:0000379	tRNA-type intron splice site recognition and cleavage	1.063385e-7
GO:0060161	positive regulation of dopamine receptor signaling pathway	1.076261e-7
GO:0006863	purine base transport	2.195935e-7
GO:0015855	pyrimidine base transport	2.270535e-7
GO:0048569	post-embryonic organ development	2.979716e-7
GO:0051383	kinetochore organization	3.064916e-7
GO:0015851	nucleobase transport	4.403906e-7
GO:0042632	cholesterol homeostasis	5.025530e-7
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	6.471312e-7
GO:0035409	histone H3-Y41 phosphorylation	7.344917e-7
GO:0008636	activation of caspase activity by protein phosphorylation	7.344917e-7
GO:0051382	kinetochore assembly	7.524164e-7
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	9.797346e-7
GO:0055088	lipid homeostasis	1.010064e-6
GO:0070836	caveola assembly	1.042415e-6
GO:0034111	negative regulation of homotypic cell-cell adhesion	1.498099e-6
GO:0042953	lipoprotein transport	1.640191e-6
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	2.169302e-6
GO:0031081	nuclear pore distribution	2.169302e-6
GO:0015942	formate metabolic process	2.286501e-6
GO:0051646	mitochondrion localization	3.589697e-6
GO:0045019	negative regulation of nitric oxide biosynthetic process	5.432470e-6
GO:0052200	response to host defenses	6.663356e-6
GO:0009396	folic acid-containing compound biosynthetic process	6.826471e-6
GO:0006335	DNA replication-dependent nucleosome assembly	7.672178e-6
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	8.751918e-6
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	8.751918e-6
GO:0016046	detection of fungus	8.751918e-6
GO:0006907	pinocytosis	8.847010e-6
GO:0032971	regulation of muscle filament sliding	8.883585e-6
GO:0051915	induction of synaptic plasticity by chemical substance	9.850825e-6
GO:0060399	positive regulation of growth hormone receptor signaling pathway	1.061019e-5
GO:0015721	bile acid and bile salt transport	1.331285e-5
GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	1.496285e-5
GO:0031959	mineralocorticoid receptor signaling pathway	1.698312e-5
GO:0071529	cementum mineralization	1.754492e-5
GO:0046514	ceramide catabolic process	1.883830e-5
GO:0060334	regulation of interferon-gamma-mediated signaling pathway	2.400394e-5
GO:0015722	canalicular bile acid transport	2.470265e-5
GO:0060574	intestinal epithelial cell maturation	2.572626e-5
GO:0034508	centromere complex assembly	2.652194e-5
GO:0006182	cGMP biosynthetic process	2.888794e-5
GO:0045359	positive regulation of interferon-beta biosynthetic process	2.893504e-5
GO:0051001	negative regulation of nitric-oxide synthase activity	3.139912e-5
GO:0006926	virus-infected cell apoptosis	3.583498e-5
GO:0051354	negative regulation of oxidoreductase activity	3.852014e-5
GO:0030683	evasion by virus of host immune response	3.990828e-5
GO:0007628	adult walking behavior	4.014859e-5
GO:0065004	protein-DNA complex assembly	4.024663e-5
GO:0006853	carnitine shuttle	4.041360e-5
GO:0006529	asparagine biosynthetic process	4.099051e-5
GO:0031116	positive regulation of microtubule polymerization	5.001851e-5
GO:0045357	regulation of interferon-beta biosynthetic process	5.009418e-5
GO:0048676	axon extension involved in development	5.455545e-5
GO:0042993	positive regulation of transcription factor import into nucleus	5.494554e-5
GO:0010799	regulation of peptidyl-threonine phosphorylation	5.528738e-5
GO:0000076	DNA replication checkpoint	5.795651e-5
GO:0034110	regulation of homotypic cell-cell adhesion	6.360660e-5
GO:0031579	membrane raft organization	6.690624e-5
GO:0021509	roof plate formation	6.856339e-5
GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	7.165671e-5
GO:0006790	sulfur compound metabolic process	8.145992e-5
GO:0060356	leucine import	8.470982e-5
GO:0006260	DNA replication	8.786570e-5
GO:0042723	thiamine-containing compound metabolic process	8.872516e-5
GO:0046521	sphingoid catabolic process	9.358777e-5
GO:0022408	negative regulation of cell-cell adhesion	1.019432e-4
GO:0070672	response to interleukin-15	1.052648e-4
GO:0060061	Spemann organizer formation	1.102564e-4
GO:0047497	mitochondrion transport along microtubule	1.105659e-4
GO:0015918	sterol transport	1.299368e-4
GO:0031022	nuclear migration along microfilament	1.365918e-4
GO:0015718	monocarboxylic acid transport	1.388294e-4
GO:0048554	positive regulation of metalloenzyme activity	1.394353e-4
GO:0045039	protein import into mitochondrial inner membrane	1.394353e-4
GO:0006598	polyamine catabolic process	1.400465e-4
GO:0032439	endosome localization	1.401380e-4
GO:0032707	negative regulation of interleukin-23 production	1.418481e-4
GO:0060480	lung goblet cell differentiation	1.418481e-4
GO:0030208	dermatan sulfate biosynthetic process	1.418481e-4
GO:0042136	neurotransmitter biosynthetic process	1.431101e-4
GO:0002275	myeloid cell activation involved in immune response	1.440517e-4
GO:0014012	peripheral nervous system axon regeneration	1.472556e-4
GO:0060435	bronchiole development	1.724026e-4
GO:0072530	purine-containing compound transmembrane transport	1.728063e-4
GO:0006641	triglyceride metabolic process	1.781833e-4
GO:0031247	actin rod assembly	1.805358e-4
GO:0002537	nitric oxide production involved in inflammatory response	1.805358e-4
GO:0044258	intestinal lipid catabolic process	1.807135e-4
GO:0018350	protein esterification	1.807135e-4
GO:0060159	regulation of dopamine receptor signaling pathway	1.845243e-4
GO:0070541	response to platinum ion	1.976511e-4
GO:0046653	tetrahydrofolate metabolic process	2.001486e-4
GO:0032222	regulation of synaptic transmission, cholinergic	2.084153e-4
GO:0035722	interleukin-12-mediated signaling pathway	2.117162e-4
GO:0015931	nucleobase-containing compound transport	2.170458e-4
GO:0051642	centrosome localization	2.205875e-4
GO:0071105	response to interleukin-11	2.243257e-4
GO:0006541	glutamine metabolic process	2.322474e-4
GO:0006334	nucleosome assembly	2.337121e-4
GO:0060056	mammary gland involution	2.399233e-4
GO:0009566	fertilization	2.400355e-4
GO:0071320	cellular response to cAMP	2.428381e-4
GO:0002069	columnar/cuboidal epithelial cell maturation	2.559167e-4
GO:0045348	positive regulation of MHC class II biosynthetic process	2.588206e-4
GO:0010722	regulation of ferrochelatase activity	2.788148e-4
GO:0051292	nuclear pore complex assembly	2.956513e-4
GO:0016338	calcium-independent cell-cell adhesion	2.997304e-4
GO:0051450	myoblast proliferation	3.077528e-4
GO:0032365	intracellular lipid transport	3.080281e-4
GO:0032929	negative regulation of superoxide anion generation	3.088167e-4
GO:0034723	DNA replication-dependent nucleosome organization	3.088167e-4
GO:0006898	receptor-mediated endocytosis	3.113644e-4
GO:0001774	microglial cell activation	3.140420e-4
GO:0001300	chronological cell aging	3.163037e-4
GO:0007262	STAT protein import into nucleus	3.249170e-4
GO:0015793	glycerol transport	3.249170e-4
GO:0006639	acylglycerol metabolic process	3.345176e-4
GO:0009064	glutamine family amino acid metabolic process	3.623323e-4
GO:0030901	midbrain development	3.877694e-4
GO:0030301	cholesterol transport	3.907769e-4
GO:0061143	alveolar primary septum development	4.038126e-4
GO:0071824	protein-DNA complex subunit organization	4.125951e-4
GO:0001839	neural plate morphogenesis	4.149613e-4
GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	4.265288e-4
GO:0034373	intermediate-density lipoprotein particle remodeling	4.412424e-4
GO:0060398	regulation of growth hormone receptor signaling pathway	4.418354e-4
GO:0032609	interferon-gamma production	4.703927e-4
GO:0032769	negative regulation of monooxygenase activity	4.787824e-4
GO:0006290	pyrimidine dimer repair	4.840991e-4
GO:0045653	negative regulation of megakaryocyte differentiation	4.895260e-4
GO:0051659	maintenance of mitochondrion location	4.912845e-4
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	4.912845e-4
GO:0051310	metaphase plate congression	4.925270e-4
GO:0031077	post-embryonic camera-type eye development	5.059629e-4
GO:0045638	negative regulation of myeloid cell differentiation	5.172739e-4
GO:0006540	glutamate decarboxylation to succinate	5.254467e-4
GO:0035456	response to interferon-beta	5.317246e-4
GO:0031112	positive regulation of microtubule polymerization or depolymerization	5.909108e-4
GO:0034374	low-density lipoprotein particle remodeling	5.960012e-4
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	6.035557e-4
GO:0015849	organic acid transport	6.143337e-4
GO:0034346	positive regulation of type III interferon production	6.502809e-4
GO:0006406	mRNA export from nucleus	7.095045e-4
GO:0033561	regulation of water loss via skin	7.187543e-4
GO:0000105	histidine biosynthetic process	7.187543e-4
GO:0046677	response to antibiotic	7.199062e-4
GO:0035564	regulation of kidney size	7.634373e-4
GO:0031915	positive regulation of synaptic plasticity	7.649268e-4
GO:0042755	eating behavior	7.900524e-4
GO:0031103	axon regeneration	8.160116e-4
GO:0006760	folic acid-containing compound metabolic process	8.199165e-4
GO:0044062	regulation of excretion	8.361554e-4
GO:0006638	neutral lipid metabolic process	8.503856e-4
GO:0019836	hemolysis by symbiont of host erythrocytes	8.510800e-4
GO:0006405	RNA export from nucleus	8.551884e-4
GO:0015827	tryptophan transport	8.608980e-4
GO:0015837	amine transport	8.634003e-4
GO:0051654	establishment of mitochondrion localization	8.925016e-4
GO:0033683	nucleotide-excision repair, DNA incision	9.042896e-4
GO:0016137	glycoside metabolic process	9.042896e-4
GO:0060395	SMAD protein signal transduction	9.813865e-4
GO:0090193	positive regulation of glomerulus development	9.854970e-4
GO:0032055	negative regulation of translation in response to stress	9.854970e-4
GO:0006620	posttranslational protein targeting to membrane	9.854970e-4
GO:0006108	malate metabolic process	9.956751e-4
GO:0042157	lipoprotein metabolic process	1.013872e-3
GO:0071318	cellular response to ATP	1.052751e-3
GO:0043508	negative regulation of JUN kinase activity	1.053437e-3
GO:0060638	mesenchymal-epithelial cell signaling	1.072599e-3
GO:2000173	negative regulation of branching morphogenesis of a nerve	1.080790e-3
GO:0019079	viral genome replication	1.080961e-3
GO:0006668	sphinganine-1-phosphate metabolic process	1.084834e-3
GO:0034638	phosphatidylcholine catabolic process	1.114776e-3
GO:0016125	sterol metabolic process	1.121458e-3
GO:0044003	modification by symbiont of host morphology or physiology	1.151913e-3
GO:0003333	amino acid transmembrane transport	1.166556e-3
GO:0002237	response to molecule of bacterial origin	1.180200e-3
GO:0030204	chondroitin sulfate metabolic process	1.186824e-3
GO:0009617	response to bacterium	1.196413e-3
GO:0035458	cellular response to interferon-beta	1.216691e-3
GO:0034372	very-low-density lipoprotein particle remodeling	1.221913e-3
GO:0006413	translational initiation	1.246497e-3
GO:0061038	uterus morphogenesis	1.317628e-3
GO:0006528	asparagine metabolic process	1.322341e-3
GO:0016139	glycoside catabolic process	1.322721e-3
GO:0015872	dopamine transport	1.373817e-3
GO:0046942	carboxylic acid transport	1.375015e-3
GO:0006869	lipid transport	1.405371e-3
GO:0009744	response to sucrose stimulus	1.437797e-3
GO:0035356	cellular triglyceride homeostasis	1.475150e-3
GO:0007162	negative regulation of cell adhesion	1.540146e-3
GO:0033629	negative regulation of cell adhesion mediated by integrin	1.570564e-3
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	1.571345e-3
GO:0032760	positive regulation of tumor necrosis factor production	1.628480e-3
GO:0060644	mammary gland epithelial cell differentiation	1.687176e-3
GO:0045210	FasL biosynthetic process	1.745749e-3
GO:0042753	positive regulation of circadian rhythm	1.748625e-3
GO:0030104	water homeostasis	1.776326e-3
GO:0052509	positive regulation by symbiont of host defense response	1.787608e-3
GO:0015820	leucine transport	1.849287e-3
GO:0001840	neural plate development	1.851448e-3
GO:0021700	developmental maturation	1.854365e-3
GO:0030853	negative regulation of granulocyte differentiation	1.864135e-3
GO:0070328	triglyceride homeostasis	2.001139e-3
GO:0060401	cytosolic calcium ion transport	2.010514e-3
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	2.058092e-3
GO:0046689	response to mercury ion	2.069939e-3
GO:0042116	macrophage activation	2.069939e-3
GO:0009066	aspartate family amino acid metabolic process	2.150598e-3
GO:0060712	spongiotrophoblast layer development	2.154062e-3
GO:0042158	lipoprotein biosynthetic process	2.176074e-3
GO:0060306	regulation of membrane repolarization	2.243393e-3
GO:0071379	cellular response to prostaglandin stimulus	2.287539e-3
GO:2000096	positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway	2.295224e-3
GO:0035813	regulation of renal sodium excretion	2.325783e-3
GO:0006772	thiamine metabolic process	2.332217e-3
GO:0002064	epithelial cell development	2.332300e-3
GO:0048388	endosomal lumen acidification	2.344204e-3
GO:0071673	positive regulation of smooth muscle cell chemotaxis	2.344204e-3
GO:0007210	serotonin receptor signaling pathway	2.392896e-3
GO:0019896	axon transport of mitochondrion	2.442685e-3
GO:0016925	protein sumoylation	2.450554e-3
GO:0010889	regulation of sequestering of triglyceride	2.461243e-3
GO:0042159	lipoprotein catabolic process	2.472546e-3
GO:0060118	vestibular receptor cell development	2.571272e-3
GO:0030704	vitelline membrane formation	2.571272e-3
GO:0014827	intestine smooth muscle contraction	2.644247e-3
GO:0010106	cellular response to iron ion starvation	2.698238e-3
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	2.721922e-3
GO:0031989	bombesin receptor signaling pathway	2.745513e-3
GO:0045346	regulation of MHC class II biosynthetic process	2.866868e-3
GO:0035166	post-embryonic hemopoiesis	2.894848e-3
GO:0061028	establishment of endothelial barrier	3.026613e-3
GO:0043555	regulation of translation in response to stress	3.078293e-3
GO:0022007	convergent extension involved in neural plate elongation	3.097845e-3
GO:0071702	organic substance transport	3.106665e-3
GO:0050884	neuromuscular process controlling posture	3.128681e-3
GO:2000344	positive regulation of acrosome reaction	3.158930e-3
GO:0034379	very-low-density lipoprotein particle assembly	3.159852e-3
GO:0007252	I-kappaB phosphorylation	3.176378e-3
GO:0018065	protein-cofactor linkage	3.193469e-3
GO:0050654	chondroitin sulfate proteoglycan metabolic process	3.249512e-3
GO:0002070	epithelial cell maturation	3.282352e-3
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.311272e-3
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	3.328894e-3
GO:0045773	positive regulation of axon extension	3.372858e-3
GO:0042559	pteridine-containing compound biosynthetic process	3.390854e-3
GO:0072531	pyrimidine-containing compound transmembrane transport	3.418955e-3
GO:0001514	selenocysteine incorporation	3.432502e-3
GO:0031952	regulation of protein autophosphorylation	3.442252e-3
GO:0007631	feeding behavior	3.450336e-3
GO:0006029	proteoglycan metabolic process	3.495972e-3
GO:0071705	nitrogen compound transport	3.535729e-3
GO:0007062	sister chromatid cohesion	3.545883e-3
GO:0035803	egg coat formation	3.562068e-3
GO:0070302	regulation of stress-activated protein kinase signaling cascade	3.603580e-3
GO:0031642	negative regulation of myelination	3.608527e-3
GO:0031953	negative regulation of protein autophosphorylation	3.621107e-3
GO:0021527	spinal cord association neuron differentiation	3.693122e-3
GO:0019433	triglyceride catabolic process	3.697926e-3
GO:0006662	glycerol ether metabolic process	3.737929e-3
GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway	3.761066e-3
GO:0060464	lung lobe formation	3.817078e-3
GO:0046588	negative regulation of calcium-dependent cell-cell adhesion	3.817078e-3
GO:0032981	mitochondrial respiratory chain complex I assembly	3.852067e-3
GO:0009187	cyclic nucleotide metabolic process	3.878864e-3
GO:0045713	low-density lipoprotein particle receptor biosynthetic process	3.959401e-3
GO:0033590	response to cobalamin	3.959401e-3
GO:0003290	atrial septum secundum morphogenesis	3.959401e-3
GO:0006117	acetaldehyde metabolic process	3.959401e-3
GO:0072321	chaperone-mediated protein transport	3.989467e-3
GO:0045687	positive regulation of glial cell differentiation	4.016836e-3
GO:0048312	intracellular distribution of mitochondria	4.130653e-3
GO:0007195	inhibition of adenylate cyclase activity by dopamine receptor signaling pathway	4.130653e-3
GO:0051647	nucleus localization	4.132086e-3
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	4.186939e-3
GO:0045212	neurotransmitter receptor biosynthetic process	4.186939e-3
GO:0032223	negative regulation of synaptic transmission, cholinergic	4.186939e-3
GO:0045947	negative regulation of translational initiation	4.336396e-3
GO:0031497	chromatin assembly	4.343540e-3
GO:0000186	activation of MAPKK activity	4.419831e-3
GO:0016226	iron-sulfur cluster assembly	4.530866e-3
GO:0048012	hepatocyte growth factor receptor signaling pathway	4.532754e-3
GO:0032497	detection of lipopolysaccharide	4.581120e-3
GO:0060539	diaphragm development	4.618995e-3
GO:0040023	establishment of nucleus localization	4.640992e-3
GO:0007204	elevation of cytosolic calcium ion concentration	4.697110e-3
GO:0045446	endothelial cell differentiation	4.699572e-3
GO:0060575	intestinal epithelial cell differentiation	4.725964e-3
GO:0060339	negative regulation of type I interferon-mediated signaling pathway	4.730725e-3
GO:0008216	spermidine metabolic process	4.730725e-3
GO:0015879	carnitine transport	4.753202e-3
GO:0045472	response to ether	4.783217e-3
GO:0019230	proprioception	4.818946e-3
GO:0046475	glycerophospholipid catabolic process	4.836472e-3
GO:0006467	protein thiol-disulfide exchange	4.867919e-3
GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway	4.874287e-3
GO:0031223	auditory behavior	4.948792e-3
GO:0010884	positive regulation of lipid storage	5.168676e-3
GO:0006813	potassium ion transport	5.199893e-3
GO:0030157	pancreatic juice secretion	5.204986e-3
GO:0042346	positive regulation of NF-kappaB import into nucleus	5.274322e-3
GO:0030855	epithelial cell differentiation	5.307807e-3
GO:0032647	regulation of interferon-alpha production	5.334308e-3
GO:0035815	positive regulation of renal sodium excretion	5.334308e-3
GO:0060968	regulation of gene silencing	5.339596e-3
GO:0031114	regulation of microtubule depolymerization	5.381358e-3
GO:0009595	detection of biotic stimulus	5.423308e-3
GO:0044242	cellular lipid catabolic process	5.490291e-3
GO:0090331	negative regulation of platelet aggregation	5.527760e-3
GO:0061110	dense core granule biogenesis	5.527760e-3
GO:0042628	mating plug formation	5.527760e-3
GO:0061108	seminal vesicle epithelium development	5.527760e-3
GO:0010248	establishment or maintenance of transmembrane electrochemical gradient	5.530298e-3
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	5.620791e-3
GO:0061162	establishment of monopolar cell polarity	5.626055e-3
GO:0070207	protein homotrimerization	5.752551e-3
GO:0051099	positive regulation of binding	5.753057e-3
GO:0045540	regulation of cholesterol biosynthetic process	5.757532e-3
GO:0052565	response to defense-related host nitric oxide production	5.789420e-3
GO:0030844	positive regulation of intermediate filament depolymerization	5.789420e-3
GO:0007097	nuclear migration	5.832314e-3
GO:0009649	entrainment of circadian clock	5.875719e-3
GO:0031558	induction of apoptosis in response to chemical stimulus	5.930866e-3
GO:0045345	positive regulation of MHC class I biosynthetic process	5.959094e-3
GO:0010876	lipid localization	6.153379e-3
GO:0015791	polyol transport	6.173054e-3
GO:0007026	negative regulation of microtubule depolymerization	6.220145e-3
GO:0071104	response to interleukin-9	6.256698e-3
GO:0060691	epithelial cell maturation involved in salivary gland development	6.256698e-3
GO:0033292	T-tubule organization	6.256698e-3
GO:0060096	serotonin secretion, neurotransmission	6.256698e-3
GO:0060299	negative regulation of sarcomere organization	6.256698e-3
GO:0061205	paramesonephric duct development	6.311773e-3
GO:0032928	regulation of superoxide anion generation	6.383088e-3
GO:0048711	positive regulation of astrocyte differentiation	6.457816e-3
GO:0072134	nephrogenic mesenchyme morphogenesis	6.466884e-3
GO:0003184	pulmonary valve morphogenesis	6.466884e-3
GO:0032057	negative regulation of translational initiation in response to stress	6.466884e-3
GO:0044089	positive regulation of cellular component biogenesis	6.574529e-3
GO:0031557	induction of programmed cell death in response to chemical stimulus	6.626170e-3
GO:0060662	salivary gland cavitation	6.784513e-3
GO:0032006	regulation of TOR signaling cascade	6.830348e-3
GO:0034728	nucleosome organization	6.840558e-3
GO:0007007	inner mitochondrial membrane organization	6.871834e-3
GO:0060402	calcium ion transport into cytosol	6.942524e-3
GO:0001885	endothelial cell development	7.039359e-3
GO:0010389	regulation of G2/M transition of mitotic cell cycle	7.101814e-3
GO:0006706	steroid catabolic process	7.127888e-3
GO:0018283	iron incorporation into metallo-sulfur cluster	7.175615e-3
GO:0010890	positive regulation of sequestering of triglyceride	7.243254e-3
GO:0031427	response to methotrexate	7.513403e-3
GO:0032799	low-density lipoprotein receptor particle metabolic process	7.513403e-3
GO:0018352	protein-pyridoxal-5-phosphate linkage	7.513403e-3
GO:0000718	nucleotide-excision repair, DNA damage removal	7.562143e-3
GO:0045792	negative regulation of cell size	7.731573e-3
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	7.780023e-3
GO:0030490	maturation of SSU-rRNA	7.826597e-3
GO:0046477	glycosylceramide catabolic process	7.826597e-3
GO:0051028	mRNA transport	7.851415e-3
GO:0042522	regulation of tyrosine phosphorylation of Stat5 protein	7.890461e-3
GO:0042255	ribosome assembly	7.933574e-3
GO:0046039	GTP metabolic process	7.950828e-3
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	8.002903e-3
GO:0046464	acylglycerol catabolic process	8.375903e-3
GO:0071671	regulation of smooth muscle cell chemotaxis	8.434440e-3
GO:0019255	glucose 1-phosphate metabolic process	8.434440e-3
GO:0060482	lobar bronchus development	8.434440e-3
GO:0034370	triglyceride-rich lipoprotein particle remodeling	8.572736e-3
GO:0071827	plasma lipoprotein particle organization	8.675482e-3
GO:0014015	positive regulation of gliogenesis	8.806646e-3
GO:0010572	positive regulation of platelet activation	8.876000e-3
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	8.896771e-3
GO:0061002	negative regulation of dendritic spine morphogenesis	8.973667e-3
GO:0060466	activation of meiosis involved in egg activation	8.973667e-3
GO:0000920	cytokinetic cell separation	8.973667e-3
GO:0008206	bile acid metabolic process	9.027403e-3
GO:0032781	positive regulation of ATPase activity	9.050261e-3
GO:0042420	dopamine catabolic process	9.070691e-3
GO:0006542	glutamine biosynthetic process	9.184933e-3
GO:0006612	protein targeting to membrane	9.226951e-3
GO:0042977	activation of JAK2 kinase activity	9.262890e-3
GO:0042305	specification of segmental identity, mandibular segment	9.290409e-3
GO:0002033	vasodilation by angiotensin involved in regulation of systemic arterial blood pressure	9.290409e-3
GO:0018184	protein polyamination	9.290409e-3
GO:0048678	response to axon injury	9.296975e-3
GO:0006739	NADP metabolic process	9.370479e-3
GO:0045630	positive regulation of T-helper 2 cell differentiation	9.521346e-3
GO:0060711	labyrinthine layer development	9.537681e-3
GO:0018209	peptidyl-serine modification	9.555511e-3
GO:2000052	positive regulation of non-canonical Wnt receptor signaling pathway	9.592155e-3
GO:0043585	nose morphogenesis	9.592155e-3
GO:0030308	negative regulation of cell growth	9.593676e-3
GO:0030317	sperm motility	9.604014e-3
GO:0070671	response to interleukin-12	9.741456e-3
GO:0002066	columnar/cuboidal epithelial cell development	9.821674e-3
GO:0042274	ribosomal small subunit biogenesis	9.933439e-3
GO:0006848	pyruvate transport	9.946947e-3
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	9.946947e-3
GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	9.946947e-3
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	9.946947e-3
GO:0031648	protein destabilization	1.005558e-2
GO:0051320	S phase	1.008017e-2
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	1.015134e-2
GO:0015810	aspartate transport	1.026278e-2
GO:0061156	pulmonary artery morphogenesis	1.029235e-2
GO:0071360	cellular response to exogenous dsRNA	1.035196e-2
GO:0050999	regulation of nitric-oxide synthase activity	1.041693e-2
GO:0060708	spongiotrophoblast differentiation	1.045447e-2
GO:0006403	RNA localization	1.067208e-2
GO:0006184	GTP catabolic process	1.078802e-2
GO:0050651	dermatan sulfate proteoglycan biosynthetic process	1.083826e-2
GO:0046330	positive regulation of JNK cascade	1.089715e-2
GO:0014056	regulation of acetylcholine secretion	1.099496e-2
GO:0070483	detection of hypoxia	1.099496e-2
GO:0045343	regulation of MHC class I biosynthetic process	1.104322e-2
GO:0007064	mitotic sister chromatid cohesion	1.106484e-2
GO:0008078	mesodermal cell migration	1.110234e-2
GO:0048844	artery morphogenesis	1.118617e-2
GO:0030149	sphingolipid catabolic process	1.126541e-2
GO:0010761	fibroblast migration	1.126541e-2
GO:0060765	regulation of androgen receptor signaling pathway	1.127125e-2
GO:0034764	positive regulation of transmembrane transport	1.140855e-2
GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	1.166946e-2
GO:0046328	regulation of JNK cascade	1.175966e-2
GO:0051100	negative regulation of binding	1.196785e-2
GO:0060338	regulation of type I interferon-mediated signaling pathway	1.197401e-2
GO:0007638	mechanosensory behavior	1.200083e-2
GO:0048563	post-embryonic organ morphogenesis	1.200914e-2
GO:0015801	aromatic amino acid transport	1.200914e-2
GO:0046113	nucleobase catabolic process	1.205947e-2
GO:0001937	negative regulation of endothelial cell proliferation	1.215221e-2
GO:0060046	regulation of acrosome reaction	1.217757e-2
GO:0033108	mitochondrial respiratory chain complex assembly	1.226225e-2
GO:0003158	endothelium development	1.227318e-2
GO:0032008	positive regulation of TOR signaling cascade	1.233334e-2
GO:0006983	ER overload response	1.244433e-2
GO:0007597	blood coagulation, intrinsic pathway	1.257403e-2
GO:0051668	localization within membrane	1.259798e-2
GO:0007218	neuropeptide signaling pathway	1.259934e-2
GO:0050658	RNA transport	1.262827e-2
GO:0032757	positive regulation of interleukin-8 production	1.265037e-2
GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway	1.270780e-2
GO:0045356	positive regulation of interferon-alpha biosynthetic process	1.270780e-2
GO:0051701	interaction with host	1.279772e-2
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	1.285351e-2
GO:0014040	positive regulation of Schwann cell differentiation	1.285351e-2
GO:0006177	GMP biosynthetic process	1.285351e-2
GO:0051657	maintenance of organelle location	1.292270e-2
GO:0006835	dicarboxylic acid transport	1.299989e-2
GO:0034369	plasma lipoprotein particle remodeling	1.311892e-2
GO:0030206	chondroitin sulfate biosynthetic process	1.313488e-2
GO:0060535	trachea cartilage morphogenesis	1.320226e-2
GO:0048639	positive regulation of developmental growth	1.324289e-2
GO:0032092	positive regulation of protein binding	1.345552e-2
GO:0014067	negative regulation of phosphatidylinositol 3-kinase cascade	1.372154e-2
GO:0010713	negative regulation of collagen metabolic process	1.372154e-2
GO:0046549	retinal cone cell development	1.372872e-2
GO:0050655	dermatan sulfate proteoglycan metabolic process	1.372872e-2
GO:0006555	methionine metabolic process	1.378235e-2
GO:0022614	membrane to membrane docking	1.383734e-2
GO:2000095	regulation of Wnt receptor signaling pathway, planar cell polarity pathway	1.386080e-2
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	1.401124e-2
GO:0046503	glycerolipid catabolic process	1.429090e-2
GO:2000286	receptor internalization involved in canonical Wnt receptor signaling pathway	1.429247e-2
GO:0014057	positive regulation of acetylcholine secretion	1.429247e-2
GO:0006412	translation	1.431914e-2
GO:0071243	cellular response to arsenic-containing substance	1.435625e-2
GO:0051712	positive regulation of killing of cells of other organism	1.435625e-2
GO:0060998	regulation of dendritic spine development	1.437014e-2
GO:0051205	protein insertion into membrane	1.444005e-2
GO:0007416	synapse assembly	1.481847e-2
GO:0031123	RNA 3'-end processing	1.484166e-2
GO:0090322	regulation of superoxide metabolic process	1.504304e-2
GO:0046795	intracellular virion transport	1.505485e-2
GO:0046341	CDP-diacylglycerol metabolic process	1.505485e-2
GO:0006164	purine nucleotide biosynthetic process	1.507271e-2
GO:0032633	interleukin-4 production	1.509016e-2
GO:0001865	NK T cell differentiation	1.509016e-2
GO:0043314	negative regulation of neutrophil degranulation	1.558293e-2
GO:0042508	tyrosine phosphorylation of Stat1 protein	1.558293e-2
GO:0051098	regulation of binding	1.564512e-2
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade	1.568106e-2
GO:0032496	response to lipopolysaccharide	1.573920e-2
GO:0030203	glycosaminoglycan metabolic process	1.574003e-2
GO:0002030	inhibitory G-protein coupled receptor phosphorylation	1.579253e-2
GO:0033326	cerebrospinal fluid secretion	1.584274e-2
GO:0008203	cholesterol metabolic process	1.591733e-2
GO:0006865	amino acid transport	1.591733e-2
GO:0051480	cytosolic calcium ion homeostasis	1.592736e-2
GO:0042558	pteridine-containing compound metabolic process	1.601497e-2
GO:0070212	protein poly-ADP-ribosylation	1.601630e-2
GO:0043393	regulation of protein binding	1.615502e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0048240	sperm capacitation	1.603861e-13
GO:0060074	synapse maturation	6.365769e-9
GO:0010722	regulation of ferrochelatase activity	1.359664e-8
GO:0043461	proton-transporting ATP synthase complex assembly	1.953500e-8
GO:0010872	regulation of cholesterol esterification	3.442389e-8
GO:0010873	positive regulation of cholesterol esterification	4.246618e-8
GO:0060971	embryonic heart tube left/right pattern formation	1.528670e-7
GO:0007258	JUN phosphorylation	1.905140e-7
GO:0045210	FasL biosynthetic process	3.120332e-7
GO:0032765	positive regulation of mast cell cytokine production	3.120332e-7
GO:0002431	Fc receptor mediated stimulatory signaling pathway	3.120332e-7
GO:0007254	JNK cascade	4.329923e-7
GO:0032915	positive regulation of transforming growth factor beta2 production	5.944495e-7
GO:0031098	stress-activated protein kinase signaling cascade	7.252970e-7
GO:0070286	axonemal dynein complex assembly	1.523891e-6
GO:0060764	cell-cell signaling involved in mammary gland development	1.638170e-6
GO:0016540	protein autoprocessing	2.082320e-6
GO:0018283	iron incorporation into metallo-sulfur cluster	2.282429e-6
GO:0001805	positive regulation of type III hypersensitivity	4.231432e-6
GO:0019230	proprioception	4.945292e-6
GO:0045963	negative regulation of dopamine metabolic process	5.583484e-6
GO:0050668	positive regulation of homocysteine metabolic process	5.583484e-6
GO:0007586	digestion	5.906968e-6
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	7.006798e-6
GO:0009169	purine ribonucleoside monophosphate catabolic process	7.376614e-6
GO:0007286	spermatid development	8.388427e-6
GO:2000781	positive regulation of double-strand break repair	8.493952e-6
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	8.677865e-6
GO:0071071	regulation of phospholipid biosynthetic process	9.698921e-6
GO:0043129	surfactant homeostasis	1.213236e-5
GO:0071214	cellular response to abiotic stimulus	1.272974e-5
GO:0000302	response to reactive oxygen species	1.363495e-5
GO:0070071	proton-transporting two-sector ATPase complex assembly	1.735718e-5
GO:0060928	atrioventricular node cell development	2.164164e-5
GO:0060929	atrioventricular node cell fate commitment	2.164164e-5
GO:0003168	cardiac Purkinje fiber cell differentiation	2.164164e-5
GO:0015739	sialic acid transport	2.164164e-5
GO:0006258	UDP-glucose catabolic process	2.164164e-5
GO:0003342	proepicardium development	2.164164e-5
GO:0006011	UDP-glucose metabolic process	2.393402e-5
GO:0043691	reverse cholesterol transport	2.591787e-5
GO:0070482	response to oxygen levels	2.673928e-5
GO:0071072	negative regulation of phospholipid biosynthetic process	2.827663e-5
GO:0001812	positive regulation of type I hypersensitivity	3.231756e-5
GO:0006783	heme biosynthetic process	3.515303e-5
GO:0030149	sphingolipid catabolic process	3.668889e-5
GO:0006611	protein export from nucleus	4.015040e-5
GO:0034599	cellular response to oxidative stress	4.062683e-5
GO:0007501	mesodermal cell fate specification	4.205907e-5
GO:0046466	membrane lipid catabolic process	4.216725e-5
GO:0046148	pigment biosynthetic process	4.701682e-5
GO:0048554	positive regulation of metalloenzyme activity	4.718466e-5
GO:0018364	peptidyl-glutamine methylation	4.902864e-5
GO:0051176	positive regulation of sulfur metabolic process	6.023856e-5
GO:0001666	response to hypoxia	6.234103e-5
GO:0000305	response to oxygen radical	6.860862e-5
GO:0042053	regulation of dopamine metabolic process	7.358922e-5
GO:0060620	regulation of cholesterol import	8.170741e-5
GO:0003029	detection of hypoxic conditions in blood by carotid body chemoreceptor signaling	8.892186e-5
GO:0014074	response to purine-containing compound	9.168994e-5
GO:0030300	regulation of intestinal cholesterol absorption	1.036832e-4
GO:0032049	cardiolipin biosynthetic process	1.057714e-4
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	1.057714e-4
GO:0042742	defense response to bacterium	1.162416e-4
GO:0065005	protein-lipid complex assembly	1.174593e-4
GO:0060695	negative regulation of cholesterol transporter activity	1.191090e-4
GO:0060480	lung goblet cell differentiation	1.191090e-4
GO:0015759	beta-glucoside transport	1.191090e-4
GO:0055072	iron ion homeostasis	1.244543e-4
GO:0051865	protein autoubiquitination	1.273042e-4
GO:0031000	response to caffeine	1.318931e-4
GO:0008356	asymmetric cell division	1.436824e-4
GO:0060574	intestinal epithelial cell maturation	1.557919e-4
GO:0042069	regulation of catecholamine metabolic process	1.662293e-4
GO:0048515	spermatid differentiation	1.677680e-4
GO:0002385	mucosal immune response	1.734767e-4
GO:0072592	oxygen metabolic process	1.757105e-4
GO:0038007	netrin-activated signaling pathway	1.765836e-4
GO:0006621	protein retention in ER lumen	1.834659e-4
GO:0001798	positive regulation of type IIa hypersensitivity	1.888330e-4
GO:0006003	fructose 2,6-bisphosphate metabolic process	1.904481e-4
GO:0070318	positive regulation of G0 to G1 transition	1.957785e-4
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	1.957785e-4
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	1.957785e-4
GO:0032230	positive regulation of synaptic transmission, GABAergic	2.038010e-4
GO:0021604	cranial nerve structural organization	2.179731e-4
GO:0006188	IMP biosynthetic process	2.244078e-4
GO:0001810	regulation of type I hypersensitivity	2.244078e-4
GO:0034508	centromere complex assembly	2.335716e-4
GO:0051341	regulation of oxidoreductase activity	2.343112e-4
GO:0071034	CUT catabolic process	2.515987e-4
GO:0043312	neutrophil degranulation	2.515987e-4
GO:0051382	kinetochore assembly	2.515987e-4
GO:0002251	organ or tissue specific immune response	2.616650e-4
GO:0071843	cellular component biogenesis at cellular level	2.820564e-4
GO:0032048	cardiolipin metabolic process	2.823428e-4
GO:0046835	carbohydrate phosphorylation	2.830627e-4
GO:0033005	positive regulation of mast cell activation	2.868770e-4
GO:0046129	purine ribonucleoside biosynthetic process	2.890064e-4
GO:0051168	nuclear export	3.226550e-4
GO:0007281	germ cell development	3.444083e-4
GO:0046033	AMP metabolic process	3.459219e-4
GO:0072384	organelle transport along microtubule	3.497590e-4
GO:0042946	glucoside transport	3.510436e-4
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	3.510436e-4
GO:0060576	intestinal epithelial cell development	3.899888e-4
GO:0071478	cellular response to radiation	3.947038e-4
GO:0010845	positive regulation of reciprocal meiotic recombination	3.964203e-4
GO:0006855	drug transmembrane transport	3.975819e-4
GO:0050798	activated T cell proliferation	4.144745e-4
GO:0033026	negative regulation of mast cell apoptosis	4.348759e-4
GO:0042135	neurotransmitter catabolic process	4.418174e-4
GO:0006707	cholesterol catabolic process	4.418174e-4
GO:0042168	heme metabolic process	4.623522e-4
GO:0034435	cholesterol esterification	4.652476e-4
GO:0072661	protein targeting to plasma membrane	4.787718e-4
GO:0042398	cellular modified amino acid biosynthetic process	5.000383e-4
GO:0033554	cellular response to stress	5.127094e-4
GO:0016558	protein import into peroxisome matrix	5.315066e-4
GO:0070316	regulation of G0 to G1 transition	5.544116e-4
GO:0045416	positive regulation of interleukin-8 biosynthetic process	5.562950e-4
GO:0090045	positive regulation of deacetylase activity	5.894156e-4
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	5.894156e-4
GO:0008615	pyridoxine biosynthetic process	5.894156e-4
GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	5.920587e-4
GO:0002542	Factor XII activation	5.920587e-4
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	6.200298e-4
GO:0009167	purine ribonucleoside monophosphate metabolic process	6.322205e-4
GO:0051262	protein tetramerization	6.363190e-4
GO:0030970	retrograde protein transport, ER to cytosol	6.399492e-4
GO:0042420	dopamine catabolic process	6.482735e-4
GO:0022600	digestive system process	6.588354e-4
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	6.589647e-4
GO:0043620	regulation of DNA-dependent transcription in response to stress	6.888142e-4
GO:0006979	response to oxidative stress	7.851723e-4
GO:0042440	pigment metabolic process	7.921373e-4
GO:0048532	anatomical structure arrangement	7.994814e-4
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	8.033953e-4
GO:0046086	adenosine biosynthetic process	8.374057e-4
GO:0010045	response to nickel ion	8.374057e-4
GO:0006196	AMP catabolic process	8.374057e-4
GO:0051383	kinetochore organization	8.401573e-4
GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway	8.451274e-4
GO:0019452	L-cysteine catabolic process to taurine	8.451274e-4
GO:0003278	apoptosis involved in heart morphogenesis	8.451274e-4
GO:0002885	positive regulation of hypersensitivity	8.860134e-4
GO:0060621	negative regulation of cholesterol import	9.107490e-4
GO:0010035	response to inorganic substance	9.468571e-4
GO:0032909	regulation of transforming growth factor beta2 production	1.008710e-3
GO:0021629	olfactory nerve structural organization	1.085365e-3
GO:0009051	pentose-phosphate shunt, oxidative branch	1.085365e-3
GO:0001710	mesodermal cell fate commitment	1.100057e-3
GO:0006779	porphyrin-containing compound biosynthetic process	1.102583e-3
GO:0033025	regulation of mast cell apoptosis	1.118992e-3
GO:0042149	cellular response to glucose starvation	1.204795e-3
GO:0006270	DNA-dependent DNA replication initiation	1.252753e-3
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.252753e-3
GO:0002540	leukotriene production involved in inflammatory response	1.254343e-3
GO:0071285	cellular response to lithium ion	1.255826e-3
GO:0055085	transmembrane transport	1.256278e-3
GO:0090005	negative regulation of establishment of protein localization in plasma membrane	1.305514e-3
GO:0006432	phenylalanyl-tRNA aminoacylation	1.381893e-3
GO:0034384	high-density lipoprotein particle clearance	1.398673e-3
GO:0050770	regulation of axonogenesis	1.421861e-3
GO:0009113	purine base biosynthetic process	1.429624e-3
GO:0006982	response to lipid hydroperoxide	1.429624e-3
GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	1.492799e-3
GO:0015893	drug transport	1.527326e-3
GO:0001977	renal system process involved in regulation of blood volume	1.527424e-3
GO:0072300	positive regulation of metanephric glomerulus development	1.561283e-3
GO:0051353	positive regulation of oxidoreductase activity	1.604539e-3
GO:0070170	regulation of tooth mineralization	1.621044e-3
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	1.647581e-3
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	1.649829e-3
GO:0071248	cellular response to metal ion	1.674910e-3
GO:0055117	regulation of cardiac muscle contraction	1.681374e-3
GO:0031334	positive regulation of protein complex assembly	1.715764e-3
GO:0090201	negative regulation of release of cytochrome c from mitochondria	1.728557e-3
GO:0032929	negative regulation of superoxide anion generation	1.736382e-3
GO:0047497	mitochondrion transport along microtubule	1.807772e-3
GO:0042424	catecholamine catabolic process	1.829008e-3
GO:0006659	phosphatidylserine biosynthetic process	1.835567e-3
GO:0046434	organophosphate catabolic process	1.936984e-3
GO:0006625	protein targeting to peroxisome	1.956499e-3
GO:0060339	negative regulation of type I interferon-mediated signaling pathway	2.011025e-3
GO:0070979	protein K11-linked ubiquitination	2.066135e-3
GO:2000378	negative regulation of reactive oxygen species metabolic process	2.068008e-3
GO:0042823	pyridoxal phosphate biosynthetic process	2.106934e-3
GO:0018026	peptidyl-lysine monomethylation	2.119784e-3
GO:0032287	peripheral nervous system myelin maintenance	2.131654e-3
GO:2000017	positive regulation of determination of dorsal identity	2.155744e-3
GO:0034614	cellular response to reactive oxygen species	2.164697e-3
GO:0051668	localization within membrane	2.194667e-3
GO:0035020	regulation of Rac protein signal transduction	2.205259e-3
GO:0001525	angiogenesis	2.239199e-3
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	2.333297e-3
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	2.333297e-3
GO:0010823	negative regulation of mitochondrion organization	2.340932e-3
GO:0009119	ribonucleoside metabolic process	2.346805e-3
GO:0071482	cellular response to light stimulus	2.406159e-3
GO:0051646	mitochondrion localization	2.425766e-3
GO:0042402	cellular biogenic amine catabolic process	2.465097e-3
GO:0046898	response to cycloheximide	2.472273e-3
GO:0045333	cellular respiration	2.505108e-3
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	2.507850e-3
GO:0016338	calcium-independent cell-cell adhesion	2.508683e-3
GO:0046112	nucleobase biosynthetic process	2.510384e-3
GO:0045739	positive regulation of DNA repair	2.629431e-3
GO:0048133	male germ-line stem cell division	2.647128e-3
GO:0071277	cellular response to calcium ion	2.649186e-3
GO:0060435	bronchiole development	2.684079e-3
GO:0060335	positive regulation of interferon-gamma-mediated signaling pathway	2.734037e-3
GO:0033128	negative regulation of histone phosphorylation	2.734037e-3
GO:0006012	galactose metabolic process	2.839680e-3
GO:0043043	peptide biosynthetic process	2.851289e-3
GO:0090187	positive regulation of pancreatic juice secretion	2.876190e-3
GO:0090340	positive regulation of secretion of lysosomal enzymes	2.876190e-3
GO:0071951	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	2.876190e-3
GO:0031118	rRNA pseudouridine synthesis	2.876190e-3
GO:0090108	positive regulation of high-density lipoprotein particle assembly	2.876190e-3
GO:0048013	ephrin receptor signaling pathway	2.884989e-3
GO:0045799	positive regulation of chromatin assembly or disassembly	2.888917e-3
GO:0060217	hemangioblast cell differentiation	2.888917e-3
GO:0046038	GMP catabolic process	2.888917e-3
GO:0032264	IMP salvage	2.888917e-3
GO:0006178	guanine salvage	2.888917e-3
GO:0032263	GMP salvage	2.888917e-3
GO:0060154	cellular process regulating host cell cycle in response to virus	2.933891e-3
GO:0031659	positive regulation of cyclin-dependent protein kinase activity involved in G1/S	2.939676e-3
GO:0002318	myeloid progenitor cell differentiation	2.939676e-3
GO:0006493	protein O-linked glycosylation	2.999542e-3
GO:0021895	cerebral cortex neuron differentiation	3.031121e-3
GO:0006661	phosphatidylinositol biosynthetic process	3.088278e-3
GO:0045414	regulation of interleukin-8 biosynthetic process	3.168565e-3
GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	3.216650e-3
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	3.244172e-3
GO:0016042	lipid catabolic process	3.263511e-3
GO:0043217	myelin maintenance	3.277215e-3
GO:0034442	regulation of lipoprotein oxidation	3.277215e-3
GO:0070995	NADPH oxidation	3.280162e-3
GO:0010226	response to lithium ion	3.387353e-3
GO:0035634	response to stilbenoid	3.440076e-3
GO:0006879	cellular iron ion homeostasis	3.472906e-3
GO:0006168	adenine salvage	3.485792e-3
GO:0023021	termination of signal transduction	3.695677e-3
GO:0051541	elastin metabolic process	3.754044e-3
GO:0045646	regulation of erythrocyte differentiation	3.772312e-3
GO:0046128	purine ribonucleoside metabolic process	3.782828e-3
GO:0051654	establishment of mitochondrion localization	3.814483e-3
GO:0046709	IDP catabolic process	3.875445e-3
GO:0046032	ADP catabolic process	3.875445e-3
GO:0006177	GMP biosynthetic process	3.875445e-3
GO:0071241	cellular response to inorganic substance	3.881240e-3
GO:0032863	activation of Rac GTPase activity	3.948239e-3
GO:0002858	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	3.948239e-3
GO:0002739	regulation of cytokine secretion involved in immune response	3.966643e-3
GO:0015938	coenzyme A catabolic process	3.996694e-3
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	3.996694e-3
GO:0009589	detection of UV	3.996694e-3
GO:0006756	AMP phosphorylation	3.996694e-3
GO:0071456	cellular response to hypoxia	4.018652e-3
GO:0055090	acylglycerol homeostasis	4.021239e-3
GO:0051188	cofactor biosynthetic process	4.159450e-3
GO:0033194	response to hydroperoxide	4.266385e-3
GO:0016973	poly(A)+ mRNA export from nucleus	4.298714e-3
GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	4.375118e-3
GO:0015936	coenzyme A metabolic process	4.470156e-3
GO:0032755	positive regulation of interleukin-6 production	4.497178e-3
GO:0006796	phosphate-containing compound metabolic process	4.525896e-3
GO:0050919	negative chemotaxis	4.571479e-3
GO:0070173	regulation of enamel mineralization	4.583646e-3
GO:0071335	hair follicle cell proliferation	4.583646e-3
GO:0034721	histone H3-K4 demethylation, trimethyl-H3-K4-specific	4.583646e-3
GO:0032290	peripheral nervous system myelin formation	4.583646e-3
GO:0060381	positive regulation of single-stranded telomeric DNA binding	4.583646e-3
GO:0046340	diacylglycerol catabolic process	4.627431e-3
GO:0010639	negative regulation of organelle organization	4.713312e-3
GO:0044058	regulation of digestive system process	4.715703e-3
GO:0044003	modification by symbiont of host morphology or physiology	4.818452e-3
GO:0090193	positive regulation of glomerulus development	4.858847e-3
GO:0009116	nucleoside metabolic process	4.865270e-3
GO:0009060	aerobic respiration	4.908875e-3
GO:0021502	neural fold elevation formation	4.973201e-3
GO:0015816	glycine transport	5.043308e-3
GO:0003093	regulation of glomerular filtration	5.043308e-3
GO:0008652	cellular amino acid biosynthetic process	5.076317e-3
GO:0051205	protein insertion into membrane	5.116561e-3
GO:0007256	activation of JNKK activity	5.227155e-3
GO:0006750	glutathione biosynthetic process	5.252822e-3
GO:0034370	triglyceride-rich lipoprotein particle remodeling	5.277890e-3
GO:0050892	intestinal absorption	5.323026e-3
GO:0055026	negative regulation of cardiac muscle tissue development	5.359605e-3
GO:0006507	GPI anchor release	5.359605e-3
GO:0000147	actin cortical patch assembly	5.359605e-3
GO:0000303	response to superoxide	5.403322e-3
GO:0090199	regulation of release of cytochrome c from mitochondria	5.412077e-3
GO:0006685	sphingomyelin catabolic process	5.414813e-3
GO:0001732	formation of translation initiation complex	5.481449e-3
GO:0032780	negative regulation of ATPase activity	5.481449e-3
GO:0080111	DNA demethylation	5.500662e-3
GO:0002227	innate immune response in mucosa	5.624448e-3
GO:0006166	purine ribonucleoside salvage	5.724189e-3
GO:0007566	embryo implantation	5.784668e-3
GO:0034622	cellular macromolecular complex assembly	5.822933e-3
GO:0003333	amino acid transmembrane transport	5.919375e-3
GO:0019228	regulation of action potential in neuron	5.958457e-3
GO:0021675	nerve development	6.010593e-3
GO:0002883	regulation of hypersensitivity	6.053922e-3
GO:0044243	multicellular organismal catabolic process	6.189261e-3
GO:0048014	Tie receptor signaling pathway	6.196708e-3
GO:0002066	columnar/cuboidal epithelial cell development	6.247289e-3
GO:0033522	histone H2A ubiquitination	6.454904e-3
GO:2000300	regulation of synaptic vesicle exocytosis	6.556770e-3
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	6.617437e-3
GO:0010735	positive regulation of transcription via serum response element binding	6.617437e-3
GO:0032202	telomere assembly	6.617437e-3
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	6.617437e-3
GO:0002069	columnar/cuboidal epithelial cell maturation	6.617437e-3
GO:0016226	iron-sulfur cluster assembly	6.664422e-3
GO:0060338	regulation of type I interferon-mediated signaling pathway	6.812683e-3
GO:0033240	positive regulation of cellular amine metabolic process	6.812683e-3
GO:0035510	DNA dealkylation	6.812683e-3
GO:0032314	regulation of Rac GTPase activity	6.822811e-3
GO:0070988	demethylation	6.843543e-3
GO:0022613	ribonucleoprotein complex biogenesis	6.923462e-3
GO:0060972	left/right pattern formation	6.940499e-3
GO:0071415	cellular response to purine-containing compound	7.001234e-3
GO:0046940	nucleoside monophosphate phosphorylation	7.001234e-3
GO:0060160	negative regulation of dopamine receptor signaling pathway	7.001234e-3
GO:0010756	positive regulation of plasminogen activation	7.042291e-3
GO:0071542	dopaminergic neuron differentiation	7.313552e-3
GO:0045213	neurotransmitter receptor metabolic process	7.332323e-3
GO:0070838	divalent metal ion transport	7.362550e-3
GO:0000165	MAPKKK cascade	7.447838e-3
GO:0070257	positive regulation of mucus secretion	7.476057e-3
GO:0072511	divalent inorganic cation transport	7.583867e-3
GO:0060754	positive regulation of mast cell chemotaxis	7.680942e-3
GO:0045576	mast cell activation	7.934536e-3
GO:0051973	positive regulation of telomerase activity	7.995212e-3
GO:0043951	negative regulation of cAMP-mediated signaling	7.995212e-3
GO:0009253	peptidoglycan catabolic process	7.995212e-3
GO:0070189	kynurenine metabolic process	8.010424e-3
GO:0050748	negative regulation of lipoprotein metabolic process	8.010424e-3
GO:0071453	cellular response to oxygen levels	8.211554e-3
GO:0010039	response to iron ion	8.243952e-3
GO:0071722	detoxification of arsenic-containing substance	8.320140e-3
GO:0002176	male germ cell proliferation	8.320140e-3
GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep	8.320140e-3
GO:0032928	regulation of superoxide anion generation	8.480061e-3
GO:0019695	choline metabolic process	8.553634e-3
GO:0003407	neural retina development	8.569774e-3
GO:0014020	primary neural tube formation	8.658602e-3
GO:0002426	immunoglobulin production in mucosal tissue	8.704233e-3
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	8.731708e-3
GO:0060612	adipose tissue development	8.744714e-3
GO:0046514	ceramide catabolic process	8.751142e-3
GO:0034377	plasma lipoprotein particle assembly	8.839790e-3
GO:0048295	positive regulation of isotype switching to IgE isotypes	8.943266e-3
GO:0045964	positive regulation of dopamine metabolic process	8.943266e-3
GO:0010312	detoxification of zinc ion	8.943266e-3
GO:0045836	positive regulation of meiosis	8.954436e-3
GO:0050996	positive regulation of lipid catabolic process	9.103522e-3
GO:0009161	ribonucleoside monophosphate metabolic process	9.204869e-3
GO:0008202	steroid metabolic process	9.327256e-3
GO:0043089	positive regulation of Cdc42 GTPase activity	9.475246e-3
GO:0046621	negative regulation of organ growth	9.543486e-3
GO:0061088	regulation of sequestering of zinc ion	9.559919e-3
GO:0007565	female pregnancy	9.635413e-3
GO:0045065	cytotoxic T cell differentiation	9.688376e-3
GO:0021783	preganglionic parasympathetic nervous system development	9.913681e-3
GO:0070574	cadmium ion transmembrane transport	1.006948e-2
GO:0010511	regulation of phosphatidylinositol biosynthetic process	1.006948e-2
GO:0045773	positive regulation of axon extension	1.007591e-2
GO:0022011	myelination in peripheral nervous system	1.014996e-2
GO:0009746	response to hexose stimulus	1.017023e-2
GO:0001547	antral ovarian follicle growth	1.026561e-2
GO:0021602	cranial nerve morphogenesis	1.059108e-2
GO:0006406	mRNA export from nucleus	1.061029e-2
GO:0021545	cranial nerve development	1.064880e-2
GO:0006413	translational initiation	1.064880e-2
GO:0070837	dehydroascorbic acid transport	1.075283e-2
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	1.075327e-2
GO:0006942	regulation of striated muscle contraction	1.079641e-2
GO:0051026	chiasma assembly	1.080511e-2
GO:0009411	response to UV	1.082324e-2
GO:0044241	lipid digestion	1.101479e-2
GO:0050772	positive regulation of axonogenesis	1.101586e-2
GO:0015980	energy derivation by oxidation of organic compounds	1.103071e-2
GO:0009749	response to glucose stimulus	1.104390e-2
GO:0050872	white fat cell differentiation	1.109717e-2
GO:0035121	tail morphogenesis	1.111241e-2
GO:0007032	endosome organization	1.111241e-2
GO:0071479	cellular response to ionizing radiation	1.116247e-2
GO:0050830	defense response to Gram-positive bacterium	1.118501e-2
GO:0008089	anterograde axon cargo transport	1.120533e-2
GO:0001830	trophectodermal cell fate commitment	1.120533e-2
GO:0060018	astrocyte fate commitment	1.131971e-2
GO:0035964	COPI-coated vesicle budding	1.132282e-2
GO:0042439	ethanolamine-containing compound metabolic process	1.138602e-2
GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway	1.154656e-2
GO:0044273	sulfur compound catabolic process	1.154656e-2
GO:0014044	Schwann cell development	1.157890e-2
GO:0034284	response to monosaccharide stimulus	1.166880e-2
GO:0043254	regulation of protein complex assembly	1.185836e-2
GO:0001508	regulation of action potential	1.197492e-2
GO:0002702	positive regulation of production of molecular mediator of immune response	1.201268e-2
GO:0044272	sulfur compound biosynthetic process	1.207412e-2
GO:0006290	pyrimidine dimer repair	1.212198e-2
GO:0008595	anterior/posterior axis specification, embryo	1.221079e-2
GO:0031054	pre-miRNA processing	1.228866e-2
GO:0034380	high-density lipoprotein particle assembly	1.230287e-2
GO:0050848	regulation of calcium-mediated signaling	1.240830e-2
GO:0071260	cellular response to mechanical stimulus	1.269311e-2
GO:0030838	positive regulation of actin filament polymerization	1.280286e-2
GO:0019370	leukotriene biosynthetic process	1.284605e-2
GO:0031100	organ regeneration	1.288068e-2
GO:0007422	peripheral nervous system development	1.292550e-2
GO:0032763	regulation of mast cell cytokine production	1.313737e-2
GO:0019377	glycolipid catabolic process	1.318413e-2
GO:0043173	nucleotide salvage	1.329457e-2
GO:0051643	endoplasmic reticulum localization	1.329457e-2
GO:0021562	vestibulocochlear nerve development	1.329457e-2
GO:0019448	L-cysteine catabolic process	1.329457e-2
GO:0009115	xanthine catabolic process	1.329457e-2
GO:0009154	purine ribonucleotide catabolic process	1.333114e-2
GO:0071480	cellular response to gamma radiation	1.345459e-2
GO:0032228	regulation of synaptic transmission, GABAergic	1.347025e-2
GO:0021603	cranial nerve formation	1.355065e-2
GO:0018106	peptidyl-histidine phosphorylation	1.355065e-2
GO:0000209	protein polyubiquitination	1.375586e-2
GO:0042373	vitamin K metabolic process	1.380487e-2
GO:0035520	monoubiquitinated protein deubiquitination	1.380487e-2
GO:0034059	response to anoxia	1.380487e-2
GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	1.380487e-2
GO:0021527	spinal cord association neuron differentiation	1.388020e-2
GO:0071879	positive regulation of adrenergic receptor signaling pathway	1.391974e-2
GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	1.391974e-2
GO:0002730	regulation of dendritic cell cytokine production	1.391974e-2
GO:0045648	positive regulation of erythrocyte differentiation	1.404397e-2
GO:0045647	negative regulation of erythrocyte differentiation	1.411275e-2
GO:0030195	negative regulation of blood coagulation	1.411779e-2
GO:0006778	porphyrin-containing compound metabolic process	1.421760e-2
GO:0001894	tissue homeostasis	1.422725e-2
GO:0006534	cysteine metabolic process	1.441221e-2
GO:0007005	mitochondrion organization	1.453642e-2
GO:0032963	collagen metabolic process	1.454437e-2
GO:0046549	retinal cone cell development	1.466500e-2
GO:0032273	positive regulation of protein polymerization	1.468319e-2
GO:0006144	purine base metabolic process	1.469591e-2
GO:0006000	fructose metabolic process	1.469591e-2
GO:0045454	cell redox homeostasis	1.474783e-2
GO:0032862	activation of Rho GTPase activity	1.486052e-2
GO:2000015	regulation of determination of dorsal identity	1.494636e-2
GO:0006705	mineralocorticoid biosynthetic process	1.494636e-2
GO:0006283	transcription-coupled nucleotide-excision repair	1.494636e-2
GO:0006027	glycosaminoglycan catabolic process	1.494636e-2
GO:0060047	heart contraction	1.497030e-2
GO:0048706	embryonic skeletal system development	1.499265e-2
GO:0042391	regulation of membrane potential	1.507840e-2
GO:0090150	establishment of protein localization in membrane	1.509591e-2
GO:0045010	actin nucleation	1.509591e-2
GO:0043101	purine-containing compound salvage	1.509591e-2
GO:0042278	purine nucleoside metabolic process	1.527912e-2
GO:0051129	negative regulation of cellular component organization	1.540685e-2
GO:0043096	purine base salvage	1.548515e-2
GO:0035566	regulation of metanephros size	1.548515e-2
GO:0043306	positive regulation of mast cell degranulation	1.557125e-2
GO:0070541	response to platinum ion	1.557125e-2
GO:0006658	phosphatidylserine metabolic process	1.557125e-2
GO:0050808	synapse organization	1.563308e-2
GO:0090287	regulation of cellular response to growth factor stimulus	1.577055e-2
GO:0015914	phospholipid transport	1.585493e-2
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	1.588679e-2
GO:0045217	cell-cell junction maintenance	1.588679e-2
GO:0030157	pancreatic juice secretion	1.588679e-2
GO:0032439	endosome localization	1.604822e-2
GO:0015993	molecular hydrogen transport	1.604822e-2
GO:0046394	carboxylic acid biosynthetic process	1.606017e-2
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	1.608556e-2
GO:0060998	regulation of dendritic spine development	1.611233e-2
GO:0018022	peptidyl-lysine methylation	1.611819e-2
GO:0042133	neurotransmitter metabolic process	1.657494e-2
GO:0006816	calcium ion transport	1.659923e-2
GO:0031398	positive regulation of protein ubiquitination	1.663027e-2
GO:0044332	Wnt receptor signaling pathway involved in dorsal/ventral axis specification	1.675709e-2
GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	1.675709e-2
GO:0035524	proline transmembrane transport	1.676241e-2
GO:0046479	glycosphingolipid catabolic process	1.676241e-2
GO:0019054	modulation by virus of host cellular process	1.679809e-2
GO:0021700	developmental maturation	1.682761e-2
GO:0033700	phospholipid efflux	1.685604e-2
GO:0048676	axon extension involved in development	1.698894e-2
GO:0034655	nucleobase-containing compound catabolic process	1.701901e-2
GO:0001961	positive regulation of cytokine-mediated signaling pathway	1.716925e-2
GO:0009395	phospholipid catabolic process	1.721004e-2
GO:0002720	positive regulation of cytokine production involved in immune response	1.729544e-2
GO:0021563	glossopharyngeal nerve development	1.732352e-2
GO:0050771	negative regulation of axonogenesis	1.742881e-2
GO:0015804	neutral amino acid transport	1.764186e-2
GO:0072523	purine-containing compound catabolic process	1.794769e-2