MCL coexpression mm9:2145

Phase1 CAGE Peaks

	Short description
Mm9::chr15:66978015..66978059,-	p@chr15:66978015..66978059 -
Mm9::chr18:32091124..32091174,+	p1@Lims2
Mm9::chr4:149377244..149377258,-	p3@H6pd
Mm9::chr4:149377276..149377303,-	p2@H6pd

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0047936	glucose 1-dehydrogenase activity	0.00777911685918377
GO:0017057	6-phosphogluconolactonase activity	0.00777911685918377
GO:0004345	glucose-6-phosphate dehydrogenase activity	0.00777911685918377
GO:0006098	pentose-phosphate shunt	0.0124448820561999
GO:0006740	NADPH regeneration	0.0124448820561999
GO:0006739	NADP metabolic process	0.0181458027245934
GO:0006769	nicotinamide metabolic process	0.0226121789953236
GO:0019362	pyridine nucleotide metabolic process	0.0226121789953236
GO:0005925	focal adhesion	0.0226121789953236
GO:0005924	cell-substrate adherens junction	0.0226121789953236
GO:0006733	oxidoreduction coenzyme metabolic process	0.0226121789953236
GO:0030055	cell-matrix junction	0.0226692001235209
GO:0006767	water-soluble vitamin metabolic process	0.0233143341778803
GO:0006007	glucose catabolic process	0.025343456383576
GO:0046365	monosaccharide catabolic process	0.025343456383576
GO:0019320	hexose catabolic process	0.025343456383576
GO:0046164	alcohol catabolic process	0.025343456383576
GO:0005912	adherens junction	0.025343456383576
GO:0006766	vitamin metabolic process	0.025343456383576
GO:0044275	cellular carbohydrate catabolic process	0.0254108027034711
GO:0016323	basolateral plasma membrane	0.0254108027034711
GO:0016052	carbohydrate catabolic process	0.0254108027034711
GO:0006006	glucose metabolic process	0.032723093673353
GO:0004091	carboxylesterase activity	0.0336162331405122
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.0341277797270279
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	0.0354912718992774
GO:0019318	hexose metabolic process	0.0370950229187441
GO:0005996	monosaccharide metabolic process	0.0370950229187441
GO:0005792	microsome	0.0397288219619067
GO:0042598	vesicular fraction	0.0397288219619067
GO:0006732	coenzyme metabolic process	0.0397288219619067
GO:0009117	nucleotide metabolic process	0.0437860630783343
GO:0051186	cofactor metabolic process	0.0438594544916371
GO:0055086	nucleobase, nucleoside and nucleotide metabolic process	0.0441544680719521
GO:0044265	cellular macromolecule catabolic process	0.0497044630990999

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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