MCL coexpression mm9:566

Phase1 CAGE Peaks

	Short description
Mm9::chr12:106751621..106751633,+	p1@uc007oyl.1
Mm9::chr12:86630582..86630610,+	p@chr12:86630582..86630610 +
Mm9::chr13:106083084..106083095,-	p5@Rnf180
Mm9::chr13:106084737..106084746,-	p7@Rnf180
Mm9::chr15:99365295..99365313,-	p@chr15:99365295..99365313 -
Mm9::chr16:92052545..92052547,+	p@chr16:92052545..92052547 +
Mm9::chr2:142705361..142705372,-	p@chr2:142705361..142705372 -
Mm9::chr3:131159868..131159874,+	p@chr3:131159868..131159874 +
Mm9::chr6:83486463..83486470,-	p10@Actg2
Mm9::chr7:105310967..105310981,-	p7@Capn5
Mm9::chr7:105327399..105327404,-	p@chr7:105327399..105327404 -
Mm9::chr7:138455776..138455787,-	p@chr7:138455776..138455787 -
Mm9::chr8:73118365..73118411,+	p1@Isyna1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0016872	intramolecular lyase activity	0.00887525338300554
GO:0004512	inositol-3-phosphate synthase activity	0.00887525338300554
GO:0006021	inositol biosynthetic process	0.0118326986534109
GO:0008307	structural constituent of muscle	0.0319299110327307
GO:0006020	inositol metabolic process	0.0319299110327307
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	0.0413736186750924
GO:0005884	actin filament	0.0442888132739544
GO:0019319	hexose biosynthetic process	0.0442888132739544
GO:0046165	alcohol biosynthetic process	0.0442888132739544
GO:0046364	monosaccharide biosynthetic process	0.0442888132739544

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
internal genitalia	6.24e-13	9
reproductive structure	1.09e-12	26
reproductive system	1.09e-12	26
female reproductive system	1.25e-12	9
epididymis	1.75e-10	3
excretory tube	1.75e-10	3
mesonephric epithelium	1.75e-10	3
mesonephric tubule	1.75e-10	3
nephric duct	1.75e-10	3
kidney epithelium	1.75e-10	3
renal duct	1.75e-10	3
mesonephric duct	1.75e-10	3
pronephric duct	1.75e-10	3
female organism	2.21e-10	11
reproductive organ	3.11e-10	24
uterus or analog	1.84e-08	1
female reproductive organ	2.13e-08	8
oviduct	2.98e-08	1
mesonephros	4.46e-08	4
duct of male reproductive system	4.46e-08	4
male genital duct	4.46e-08	4
pronephros	4.46e-08	4
internal male genitalia	4.46e-08	4
nephrogenic cord	4.46e-08	4
urogenital ridge	4.46e-08	4
pronephric mesoderm	4.46e-08	4
rostral part of nephrogenic cord	4.46e-08	4
presumptive pronephric mesoderm	4.46e-08	4
embryonic uterus	5.22e-08	4
uterus	5.22e-08	4

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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