MCL coexpression mm9:1455

Phase1 CAGE Peaks

	Short description
Mm9::chr3:130974927..130974991,-	p1@Hadh
Mm9::chr3:130974995..130974996,-	p2@Hadh
Mm9::chr4:107596084..107596100,-	p2@Cpt2
Mm9::chr4:107596113..107596122,-	p3@Cpt2
Mm9::chr4:107596124..107596220,-	p1@Cpt2
Mm9::chr9:108564430..108564550,+	p1@Slc25a20

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0005739	mitochondrion	0.00335232242348332
GO:0006631	fatty acid metabolic process	0.00335232242348332
GO:0032787	monocarboxylic acid metabolic process	0.00335232242348332
GO:0005743	mitochondrial inner membrane	0.00335232242348332
GO:0019866	organelle inner membrane	0.00335232242348332
GO:0031966	mitochondrial membrane	0.00335232242348332
GO:0005740	mitochondrial envelope	0.00335232242348332
GO:0004095	carnitine O-palmitoyltransferase activity	0.00335232242348332
GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	0.00335232242348332
GO:0016416	O-palmitoyltransferase activity	0.00335232242348332
GO:0044429	mitochondrial part	0.00410810615792097
GO:0016406	carnitine O-acyltransferase activity	0.0041899438406562
GO:0031975	envelope	0.00453799157182207
GO:0031967	organelle envelope	0.00453799157182207
GO:0019752	carboxylic acid metabolic process	0.00565429891753072
GO:0006082	organic acid metabolic process	0.00565429891753072
GO:0044255	cellular lipid metabolic process	0.00661243880005698
GO:0031090	organelle membrane	0.00661243880005698
GO:0016409	palmitoyltransferase activity	0.00661243880005698
GO:0006629	lipid metabolic process	0.007600041905139
GO:0044444	cytoplasmic part	0.0114105288159519
GO:0008374	O-acyltransferase activity	0.0114120987087785
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.0396417957725654
GO:0050662	coenzyme binding	0.0396417957725654
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	0.0396417957725654
GO:0005737	cytoplasm	0.0483821185722341
GO:0048037	cofactor binding	0.0489670450367433
GO:0008415	acyltransferase activity	0.0489670450367433
GO:0016747	transferase activity, transferring groups other than amino-acyl groups	0.0489670450367433
GO:0016746	transferase activity, transferring acyl groups	0.0492535389499352

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
intestine	7.70e-13	31
gastrointestinal system	8.99e-10	47
epithelial tube	6.10e-09	47
digestive tract diverticulum	5.95e-08	23
sac	5.95e-08	23
mucosa	1.13e-07	15
exocrine gland	1.63e-07	25
exocrine system	1.63e-07	25
liver	1.90e-07	22
epithelial sac	1.90e-07	22
digestive gland	1.90e-07	22
epithelium of foregut-midgut junction	1.90e-07	22
anatomical boundary	1.90e-07	22
hepatobiliary system	1.90e-07	22
foregut-midgut junction	1.90e-07	22
hepatic diverticulum	1.90e-07	22
liver primordium	1.90e-07	22
septum transversum	1.90e-07	22
liver bud	1.90e-07	22
intestinal mucosa	8.62e-07	13
anatomical wall	8.62e-07	13
wall of intestine	8.62e-07	13
gastrointestinal system mucosa	8.62e-07	13

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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