Novel motif:23

name:	motif23_CGCNAT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0006396	RNA processing	6.194990e-49
GO:0000375	RNA splicing, via transesterification reactions	9.085488e-30
GO:0016071	mRNA metabolic process	6.108179e-29
GO:0034660	ncRNA metabolic process	1.179267e-27
GO:0000398	nuclear mRNA splicing, via spliceosome	4.918335e-27
GO:0008380	RNA splicing	3.611585e-26
GO:0090304	nucleic acid metabolic process	3.066955e-25
GO:0042254	ribosome biogenesis	1.717562e-24
GO:0034470	ncRNA processing	1.862017e-23
GO:0006397	mRNA processing	2.006351e-22
GO:0006353	transcription termination, DNA-dependent	4.785429e-22
GO:0022613	ribonucleoprotein complex biogenesis	2.397494e-19
GO:0006281	DNA repair	1.282257e-18
GO:0071843	cellular component biogenesis at cellular level	1.398025e-17
GO:0006369	termination of RNA polymerase II transcription	6.576513e-17
GO:0006412	translation	6.601517e-17
GO:0010467	gene expression	9.854622e-17
GO:0016032	viral reproduction	1.410200e-16
GO:0016072	rRNA metabolic process	1.913997e-16
GO:0006325	chromatin organization	5.964748e-16
GO:0006139	nucleobase-containing compound metabolic process	5.970860e-16
GO:0006364	rRNA processing	6.235852e-16
GO:0051276	chromosome organization	2.038714e-15
GO:0016070	RNA metabolic process	1.596676e-14
GO:0006259	DNA metabolic process	2.857292e-14
GO:0070647	protein modification by small protein conjugation or removal	2.275472e-13
GO:0015887	pantothenate transmembrane transport	3.522929e-13
GO:0015878	biotin transport	3.522929e-13
GO:0006415	translational termination	3.805507e-13
GO:0006414	translational elongation	1.538778e-12
GO:0009452	RNA capping	2.861819e-12
GO:0050434	positive regulation of viral transcription	4.038557e-12
GO:0016570	histone modification	4.409894e-12
GO:0032446	protein modification by small protein conjugation	6.529145e-12
GO:0016568	chromatin modification	8.154047e-12
GO:0019083	viral transcription	1.470963e-11
GO:0016567	protein ubiquitination	1.816757e-11
GO:0044265	cellular macromolecule catabolic process	2.017842e-11
GO:0016569	covalent chromatin modification	2.160951e-11
GO:0006354	transcription elongation, DNA-dependent	2.397778e-11
GO:0044260	cellular macromolecule metabolic process	2.413341e-11
GO:0009057	macromolecule catabolic process	3.266662e-11
GO:0006399	tRNA metabolic process	3.939863e-11
GO:0006370	mRNA capping	5.131271e-11
GO:0034623	cellular macromolecular complex disassembly	8.656593e-11
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	1.351149e-10
GO:0072337	modified amino acid transport	1.477373e-10
GO:0043624	cellular protein complex disassembly	1.672133e-10
GO:0006368	transcription elongation from RNA polymerase II promoter	1.801878e-10
GO:0034080	CenH3-containing nucleosome assembly at centromere	3.026829e-10
GO:0000387	spliceosomal snRNP assembly	4.953036e-10
GO:0032200	telomere organization	4.977982e-10
GO:0019058	viral infectious cycle	6.190962e-10
GO:0031055	chromatin remodeling at centromere	6.278606e-10
GO:0032984	macromolecular complex disassembly	6.506120e-10
GO:0034641	cellular nitrogen compound metabolic process	8.374533e-10
GO:0008033	tRNA processing	9.917617e-10
GO:0006333	chromatin assembly or disassembly	1.557724e-9
GO:0043241	protein complex disassembly	1.581133e-9
GO:0009451	RNA modification	2.556867e-9
GO:0019941	modification-dependent protein catabolic process	3.421878e-9
GO:0006974	response to DNA damage stimulus	3.474061e-9
GO:0046782	regulation of viral transcription	3.579896e-9
GO:0043503	skeletal muscle fiber adaptation	3.731948e-9
GO:0043632	modification-dependent macromolecule catabolic process	5.056386e-9
GO:0006511	ubiquitin-dependent protein catabolic process	8.317938e-9
GO:0034728	nucleosome organization	1.103373e-8
GO:0006302	double-strand break repair	1.121638e-8
GO:0006283	transcription-coupled nucleotide-excision repair	1.137128e-8
GO:0051443	positive regulation of ubiquitin-protein ligase activity	1.257660e-8
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.489790e-8
GO:0048285	organelle fission	1.582434e-8
GO:0006334	nucleosome assembly	1.648417e-8
GO:0006362	transcription elongation from RNA polymerase I promoter	1.879987e-8
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	2.433728e-8
GO:0070127	tRNA aminoacylation for mitochondrial protein translation	3.024370e-8
GO:0006400	tRNA modification	3.053799e-8
GO:0000279	M phase	3.139123e-8
GO:0006352	transcription initiation, DNA-dependent	3.478003e-8
GO:0000723	telomere maintenance	3.760427e-8
GO:0007067	mitosis	3.873466e-8
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.859558e-8
GO:0051603	proteolysis involved in cellular protein catabolic process	5.217885e-8
GO:0006361	transcription initiation from RNA polymerase I promoter	5.523990e-8
GO:0071824	protein-DNA complex subunit organization	5.639604e-8
GO:0010498	proteasomal protein catabolic process	5.848123e-8
GO:0000087	M phase of mitotic cell cycle	5.995176e-8
GO:0051182	coenzyme transport	6.116987e-8
GO:0030163	protein catabolic process	6.146012e-8
GO:0006807	nitrogen compound metabolic process	8.902683e-8
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.093902e-7
GO:0035518	histone H2A monoubiquitination	1.377211e-7
GO:0043543	protein acylation	1.410630e-7
GO:0031123	RNA 3'-end processing	1.524935e-7
GO:0031497	chromatin assembly	1.589612e-7
GO:0044257	cellular protein catabolic process	1.659639e-7
GO:0006473	protein acetylation	1.737131e-7
GO:0006768	biotin metabolic process	1.972317e-7
GO:0010835	regulation of protein ADP-ribosylation	2.603542e-7
GO:0032259	methylation	3.494571e-7
GO:0022415	viral reproductive process	3.562252e-7
GO:0051351	positive regulation of ligase activity	3.937743e-7
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.540663e-7
GO:0009303	rRNA transcription	5.356234e-7
GO:0051438	regulation of ubiquitin-protein ligase activity	5.976251e-7
GO:0006363	termination of RNA polymerase I transcription	6.138779e-7
GO:0031124	mRNA 3'-end processing	6.306135e-7
GO:0065004	protein-DNA complex assembly	6.560030e-7
GO:0016073	snRNA metabolic process	6.678588e-7
GO:0043044	ATP-dependent chromatin remodeling	7.540168e-7
GO:0006513	protein monoubiquitination	8.202688e-7
GO:0031627	telomeric loop formation	9.265602e-7
GO:0016973	poly(A)+ mRNA export from nucleus	9.727882e-7
GO:0051320	S phase	1.099716e-6
GO:0016180	snRNA processing	1.116835e-6
GO:0070327	thyroid hormone transport	1.159665e-6
GO:0042775	mitochondrial ATP synthesis coupled electron transport	1.384048e-6
GO:0033299	secretion of lysosomal enzymes	1.410873e-6
GO:0016573	histone acetylation	1.462383e-6
GO:0002036	regulation of L-glutamate transport	1.509348e-6
GO:0022403	cell cycle phase	1.849652e-6
GO:0018206	peptidyl-methionine modification	1.898483e-6
GO:0006475	internal protein amino acid acetylation	2.030305e-6
GO:0006367	transcription initiation from RNA polymerase II promoter	2.092271e-6
GO:0003157	endocardium development	2.186681e-6
GO:0032202	telomere assembly	2.317667e-6
GO:0044237	cellular metabolic process	2.401405e-6
GO:0034645	cellular macromolecule biosynthetic process	3.133662e-6
GO:0018394	peptidyl-lysine acetylation	3.367994e-6
GO:0043558	regulation of translational initiation in response to stress	3.477637e-6
GO:0006406	mRNA export from nucleus	3.535908e-6
GO:0006360	transcription from RNA polymerase I promoter	4.050397e-6
GO:0018393	internal peptidyl-lysine acetylation	4.138220e-6
GO:0042797	tRNA transcription from RNA polymerase III promoter	4.768218e-6
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	4.768218e-6
GO:0034621	cellular macromolecular complex subunit organization	4.819470e-6
GO:0000278	mitotic cell cycle	4.952783e-6
GO:0016233	telomere capping	5.785616e-6
GO:0035461	vitamin transmembrane transport	5.899785e-6
GO:0071156	regulation of cell cycle arrest	6.054456e-6
GO:0000236	mitotic prometaphase	6.263080e-6
GO:0000075	cell cycle checkpoint	6.325309e-6
GO:0006119	oxidative phosphorylation	6.392132e-6
GO:0046502	uroporphyrinogen III metabolic process	7.006416e-6
GO:0035522	monoubiquitinated histone H2A deubiquitination	7.300195e-6
GO:0051340	regulation of ligase activity	7.418227e-6
GO:0043555	regulation of translation in response to stress	8.923693e-6
GO:0006730	one-carbon metabolic process	9.073698e-6
GO:0031848	protection from non-homologous end joining at telomere	9.443518e-6
GO:0031860	telomeric 3' overhang formation	1.045028e-5
GO:0018192	enzyme active site formation via L-cysteine persulfide	1.045028e-5
GO:0033522	histone H2A ubiquitination	1.099971e-5
GO:0009262	deoxyribonucleotide metabolic process	1.101235e-5
GO:0000084	S phase of mitotic cell cycle	1.105562e-5
GO:0043486	histone exchange	1.163071e-5
GO:0006476	protein deacetylation	1.187100e-5
GO:0006379	mRNA cleavage	1.242045e-5
GO:0018205	peptidyl-lysine modification	1.284311e-5
GO:0035601	protein deacylation	1.349044e-5
GO:0042026	protein refolding	1.400091e-5
GO:0042255	ribosome assembly	1.431204e-5
GO:0031577	spindle checkpoint	1.449843e-5
GO:0048524	positive regulation of viral reproduction	1.452722e-5
GO:0006996	organelle organization	1.534387e-5
GO:2000119	negative regulation of sodium-dependent phosphate transport	1.686862e-5
GO:0006308	DNA catabolic process	1.751277e-5
GO:0006303	double-strand break repair via nonhomologous end joining	1.898183e-5
GO:0046755	non-lytic virus budding	2.020138e-5
GO:0000726	non-recombinational repair	2.162924e-5
GO:0051586	positive regulation of dopamine uptake	2.487146e-5
GO:0006289	nucleotide-excision repair	2.517078e-5
GO:0043170	macromolecule metabolic process	2.520604e-5
GO:0006405	RNA export from nucleus	3.013771e-5
GO:0009059	macromolecule biosynthetic process	3.205287e-5
GO:0022904	respiratory electron transport chain	3.244958e-5
GO:0034770	histone H4-K20 methylation	4.146043e-5
GO:0070979	protein K11-linked ubiquitination	4.278704e-5
GO:0031365	N-terminal protein amino acid modification	4.326252e-5
GO:0060318	definitive erythrocyte differentiation	4.392298e-5
GO:0044070	regulation of anion transport	4.594048e-5
GO:0032922	circadian regulation of gene expression	5.088868e-5
GO:0071174	mitotic cell cycle spindle checkpoint	5.172923e-5
GO:0009304	tRNA transcription	5.340253e-5
GO:0048102	autophagic cell death	5.420070e-5
GO:0016574	histone ubiquitination	5.571807e-5
GO:0006695	cholesterol biosynthetic process	5.672497e-5
GO:0031536	positive regulation of exit from mitosis	5.765704e-5
GO:0032203	telomere formation via telomerase	5.892375e-5
GO:0043039	tRNA aminoacylation	6.043104e-5
GO:0019348	dolichol metabolic process	6.426899e-5
GO:0051984	positive regulation of chromosome segregation	6.446870e-5
GO:0035621	ER to Golgi ceramide transport	6.446870e-5
GO:0008535	respiratory chain complex IV assembly	6.465934e-5
GO:0032543	mitochondrial translation	6.540868e-5
GO:0060956	endocardial cell differentiation	6.683704e-5
GO:0060847	endothelial cell fate specification	7.068173e-5
GO:0016598	protein arginylation	7.202341e-5
GO:0046491	L-methylmalonyl-CoA metabolic process	7.202341e-5
GO:0051301	cell division	7.521002e-5
GO:0071166	ribonucleoprotein complex localization	8.529629e-5
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	9.229636e-5
GO:0006383	transcription from RNA polymerase III promoter	1.030611e-4
GO:0000956	nuclear-transcribed mRNA catabolic process	1.049809e-4
GO:0060214	endocardium formation	1.067254e-4
GO:0045606	positive regulation of epidermal cell differentiation	1.067254e-4
GO:0060836	lymphatic endothelial cell differentiation	1.067511e-4
GO:0007096	regulation of exit from mitosis	1.069421e-4
GO:0000209	protein polyubiquitination	1.098828e-4
GO:0045333	cellular respiration	1.139804e-4
GO:0006418	tRNA aminoacylation for protein translation	1.169042e-4
GO:0006843	mitochondrial citrate transport	1.224872e-4
GO:0006742	NADP catabolic process	1.224872e-4
GO:0071173	spindle assembly checkpoint	1.226868e-4
GO:0022618	ribonucleoprotein complex assembly	1.248660e-4
GO:0009107	lipoate biosynthetic process	1.267770e-4
GO:0060236	regulation of mitotic spindle organization	1.272305e-4
GO:0051444	negative regulation of ubiquitin-protein ligase activity	1.274864e-4
GO:0033599	regulation of mammary gland epithelial cell proliferation	1.288181e-4
GO:0000724	double-strand break repair via homologous recombination	1.372827e-4
GO:0001522	pseudouridine synthesis	1.382583e-4
GO:0035871	protein K11-linked deubiquitination	1.429367e-4
GO:0070145	mitochondrial asparaginyl-tRNA aminoacylation	1.457641e-4
GO:0015969	guanosine tetraphosphate metabolic process	1.457641e-4
GO:0002092	positive regulation of receptor internalization	1.486347e-4
GO:0043484	regulation of RNA splicing	1.697840e-4
GO:0018026	peptidyl-lysine monomethylation	1.759799e-4
GO:0007004	telomere maintenance via telomerase	1.778273e-4
GO:0015746	citrate transport	1.787393e-4
GO:0042776	mitochondrial ATP synthesis coupled proton transport	1.795661e-4
GO:0051255	spindle midzone assembly	1.974674e-4
GO:0016575	histone deacetylation	1.984292e-4
GO:0007094	mitotic cell cycle spindle assembly checkpoint	2.041818e-4
GO:0000725	recombinational repair	2.046352e-4
GO:0006260	DNA replication	2.180199e-4
GO:0070078	histone H3-R2 demethylation	2.199103e-4
GO:0070079	histone H4-R3 demethylation	2.199103e-4
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	2.199103e-4
GO:0008355	olfactory learning	2.199103e-4
GO:0031591	wybutosine biosynthetic process	2.232435e-4
GO:0048291	isotype switching to IgG isotypes	2.232435e-4
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	2.232435e-4
GO:0002368	B cell cytokine production	2.232435e-4
GO:0006779	porphyrin-containing compound biosynthetic process	2.267160e-4
GO:0000415	negative regulation of histone H3-K36 methylation	2.287807e-4
GO:0051567	histone H3-K9 methylation	2.319418e-4
GO:0016090	prenol metabolic process	2.438970e-4
GO:0051973	positive regulation of telomerase activity	2.438970e-4
GO:0090141	positive regulation of mitochondrial fission	2.548693e-4
GO:0032055	negative regulation of translation in response to stress	2.553059e-4
GO:0006780	uroporphyrinogen III biosynthetic process	2.637961e-4
GO:0061011	hepatic duct development	2.637961e-4
GO:0034968	histone lysine methylation	2.640652e-4
GO:0009264	deoxyribonucleotide catabolic process	2.829838e-4
GO:0071826	ribonucleoprotein complex subunit organization	2.856433e-4
GO:0070159	mitochondrial threonyl-tRNA aminoacylation	2.935814e-4
GO:0090140	regulation of mitochondrial fission	3.229252e-4
GO:0002003	angiotensin maturation	3.236059e-4
GO:0045900	negative regulation of translational elongation	3.473080e-4
GO:0015742	alpha-ketoglutarate transport	3.473080e-4
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	3.491299e-4
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	3.609711e-4
GO:0006366	transcription from RNA polymerase II promoter	3.612659e-4
GO:0051028	mRNA transport	3.635861e-4
GO:0002691	regulation of cellular extravasation	3.704658e-4
GO:0006401	RNA catabolic process	4.008300e-4
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	4.483946e-4
GO:0006285	base-excision repair, AP site formation	4.532718e-4
GO:0009394	2'-deoxyribonucleotide metabolic process	4.633974e-4
GO:0043538	regulation of actin phosphorylation	4.780495e-4
GO:0035129	post-embryonic hindlimb morphogenesis	4.780495e-4
GO:0043153	entrainment of circadian clock by photoperiod	4.800921e-4
GO:0090305	nucleic acid phosphodiester bond hydrolysis	4.857574e-4
GO:0006552	leucine catabolic process	4.947622e-4
GO:0000239	pachytene	5.264091e-4
GO:0070544	histone H3-K36 demethylation	5.287433e-4
GO:0032774	RNA biosynthetic process	5.495231e-4
GO:0045963	negative regulation of dopamine metabolic process	5.516808e-4
GO:0050668	positive regulation of homocysteine metabolic process	5.516808e-4
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	5.537699e-4
GO:0000718	nucleotide-excision repair, DNA damage removal	5.616765e-4
GO:0006782	protoporphyrinogen IX biosynthetic process	5.794026e-4
GO:0034776	response to histamine	5.794026e-4
GO:0010390	histone monoubiquitination	5.846024e-4
GO:0070734	histone H3-K27 methylation	6.043012e-4
GO:0010833	telomere maintenance via telomere lengthening	6.126679e-4
GO:0034551	mitochondrial respiratory chain complex III assembly	6.143393e-4
GO:0071845	cellular component disassembly at cellular level	6.252140e-4
GO:0034227	tRNA thio-modification	6.454291e-4
GO:0006188	IMP biosynthetic process	6.454291e-4
GO:0002098	tRNA wobble uridine modification	6.454291e-4
GO:0006901	vesicle coating	6.650661e-4
GO:0035470	positive regulation of vascular wound healing	6.900178e-4
GO:0009438	methylglyoxal metabolic process	6.900178e-4
GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	7.230377e-4
GO:0002693	positive regulation of cellular extravasation	7.230377e-4
GO:0015986	ATP synthesis coupled proton transport	7.327814e-4
GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis	7.432752e-4
GO:0006054	N-acetylneuraminate metabolic process	7.567394e-4
GO:0051186	cofactor metabolic process	8.203005e-4
GO:0043096	purine base salvage	8.224819e-4
GO:0046101	hypoxanthine biosynthetic process	8.268082e-4
GO:0001510	RNA methylation	8.538432e-4
GO:0006446	regulation of translational initiation	8.672577e-4
GO:0042048	olfactory behavior	8.897367e-4
GO:0021993	initiation of neural tube closure	8.897367e-4
GO:0051168	nuclear export	8.972197e-4
GO:0009113	purine base biosynthetic process	9.295306e-4
GO:0035873	lactate transmembrane transport	9.577598e-4
GO:0045090	retroviral genome replication	9.604249e-4
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	9.604249e-4
GO:0061157	mRNA destabilization	9.604249e-4
GO:0006489	dolichyl diphosphate biosynthetic process	9.604249e-4
GO:0002536	respiratory burst involved in inflammatory response	9.604249e-4
GO:0006450	regulation of translational fidelity	9.604249e-4
GO:0000216	M/G1 transition of mitotic cell cycle	9.608439e-4
GO:0046778	modification by virus of host mRNA processing	9.752689e-4
GO:0061017	hepatoblast differentiation	9.752689e-4
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	9.752689e-4
GO:0009440	cyanate catabolic process	9.752689e-4
GO:0007093	mitotic cell cycle checkpoint	9.809072e-4
GO:0016571	histone methylation	1.006199e-3
GO:0006403	RNA localization	1.019903e-3
GO:0071103	DNA conformation change	1.053274e-3
GO:0006984	ER-nucleus signaling pathway	1.062322e-3
GO:0006903	vesicle targeting	1.075192e-3
GO:0006356	regulation of transcription from RNA polymerase I promoter	1.108621e-3
GO:0006783	heme biosynthetic process	1.122726e-3
GO:0048213	Golgi vesicle prefusion complex stabilization	1.141732e-3
GO:0070179	D-serine biosynthetic process	1.141732e-3
GO:0042450	arginine biosynthetic process via ornithine	1.141732e-3
GO:0006781	succinyl-CoA pathway	1.141732e-3
GO:0043501	skeletal muscle adaptation	1.142205e-3
GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process	1.161010e-3
GO:0019428	allantoin biosynthetic process	1.161010e-3
GO:0006551	leucine metabolic process	1.179441e-3
GO:0051095	regulation of helicase activity	1.203392e-3
GO:0051983	regulation of chromosome segregation	1.204021e-3
GO:0022411	cellular component disassembly	1.224641e-3
GO:0045116	protein neddylation	1.251594e-3
GO:0022900	electron transport chain	1.255752e-3
GO:0043048	dolichyl monophosphate biosynthetic process	1.279715e-3
GO:0070625	zymogen granule exocytosis	1.279715e-3
GO:0070171	negative regulation of tooth mineralization	1.315168e-3
GO:0051030	snRNA transport	1.324199e-3
GO:0019408	dolichol biosynthetic process	1.324199e-3
GO:0048050	post-embryonic eye morphogenesis	1.324199e-3
GO:0060271	cilium morphogenesis	1.329263e-3
GO:0043060	meiotic metaphase I plate congression	1.368095e-3
GO:0010587	miRNA catabolic process	1.368095e-3
GO:0006835	dicarboxylic acid transport	1.381569e-3
GO:0040032	post-embryonic body morphogenesis	1.431892e-3
GO:0006297	nucleotide-excision repair, DNA gap filling	1.446143e-3
GO:0032205	negative regulation of telomere maintenance	1.471083e-3
GO:0043103	hypoxanthine salvage	1.486838e-3
GO:0065001	specification of axis polarity	1.529661e-3
GO:0033601	positive regulation of mammary gland epithelial cell proliferation	1.557479e-3
GO:0021586	pons maturation	1.579651e-3
GO:0009263	deoxyribonucleotide biosynthetic process	1.598280e-3
GO:0006413	translational initiation	1.659841e-3
GO:0008272	sulfate transport	1.664439e-3
GO:0046184	aldehyde biosynthetic process	1.672785e-3
GO:0071460	cellular response to cell-matrix adhesion	1.718703e-3
GO:0000492	box C/D snoRNP assembly	1.730627e-3
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	1.757692e-3
GO:0006323	DNA packaging	1.804886e-3
GO:0051257	spindle midzone assembly involved in meiosis	1.819778e-3
GO:0007060	male meiosis chromosome segregation	1.819778e-3
GO:0042274	ribosomal small subunit biogenesis	1.831602e-3
GO:0032057	negative regulation of translational initiation in response to stress	1.841305e-3
GO:0000019	regulation of mitotic recombination	1.859091e-3
GO:0006284	base-excision repair	1.894987e-3
GO:0033108	mitochondrial respiratory chain complex assembly	2.000956e-3
GO:0045008	depyrimidination	2.106956e-3
GO:0090212	negative regulation of establishment of blood-brain barrier	2.107521e-3
GO:0006427	histidyl-tRNA aminoacylation	2.107521e-3
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	2.285381e-3
GO:0030828	positive regulation of cGMP biosynthetic process	2.321902e-3
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	2.376253e-3
GO:0046100	hypoxanthine metabolic process	2.411365e-3
GO:0046833	positive regulation of RNA export from nucleus	2.463075e-3
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	2.463075e-3
GO:0010933	positive regulation of macrophage tolerance induction	2.463075e-3
GO:0003061	positive regulation of the force of heart contraction by norepinephrine	2.463075e-3
GO:0017004	cytochrome complex assembly	2.466699e-3
GO:2000786	positive regulation of autophagic vacuole assembly	2.476702e-3
GO:0050666	regulation of homocysteine metabolic process	2.476702e-3
GO:0051325	interphase	2.505447e-3
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	2.619511e-3
GO:0006498	N-terminal protein lipidation	2.619511e-3
GO:0006458	'de novo' protein folding	2.668488e-3
GO:0006844	acyl carnitine transport	2.672546e-3
GO:0000056	ribosomal small subunit export from nucleus	2.672546e-3
GO:0006430	lysyl-tRNA aminoacylation	2.672546e-3
GO:0030967	ER-nuclear sterol response pathway	2.697571e-3
GO:0051289	protein homotetramerization	2.702065e-3
GO:0033566	gamma-tubulin complex localization	2.705314e-3
GO:0090307	spindle assembly involved in mitosis	2.774284e-3
GO:0007195	inhibition of adenylate cyclase activity by dopamine receptor signaling pathway	2.833447e-3
GO:0000244	assembly of spliceosomal tri-snRNP	2.838134e-3
GO:0034436	glycoprotein transport	2.960351e-3
GO:0009720	detection of hormone stimulus	2.960351e-3
GO:0050658	RNA transport	2.971715e-3
GO:0070972	protein localization in endoplasmic reticulum	2.973374e-3
GO:0006402	mRNA catabolic process	3.036197e-3
GO:0006385	transcription elongation from RNA polymerase III promoter	3.080787e-3
GO:0006386	termination of RNA polymerase III transcription	3.080787e-3
GO:0009062	fatty acid catabolic process	3.094757e-3
GO:0034509	centromeric core chromatin assembly	3.233144e-3
GO:0032415	regulation of sodium:hydrogen antiporter activity	3.258853e-3
GO:0051181	cofactor transport	3.292540e-3
GO:0043148	mitotic spindle stabilization	3.316324e-3
GO:0032007	negative regulation of TOR signaling cascade	3.353355e-3
GO:0007614	short-term memory	3.402824e-3
GO:0031397	negative regulation of protein ubiquitination	3.480989e-3
GO:0045426	quinone cofactor biosynthetic process	3.492967e-3
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	3.575717e-3
GO:0031558	induction of apoptosis in response to chemical stimulus	3.588596e-3
GO:0019087	transformation of host cell by virus	3.588596e-3
GO:0006457	protein folding	3.613473e-3
GO:0001946	lymphangiogenesis	3.618255e-3
GO:0030433	ER-associated protein catabolic process	3.690719e-3
GO:0051292	nuclear pore complex assembly	3.727584e-3
GO:0072526	pyridine-containing compound catabolic process	3.727584e-3
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	3.727584e-3
GO:0048561	establishment of organ orientation	3.727584e-3
GO:0032042	mitochondrial DNA metabolic process	3.754236e-3
GO:0030644	cellular chloride ion homeostasis	3.754236e-3
GO:0031018	endocrine pancreas development	3.797551e-3
GO:0042360	vitamin E metabolic process	3.828418e-3
GO:0006168	adenine salvage	3.828418e-3
GO:0006310	DNA recombination	3.883053e-3
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	4.047445e-3
GO:0071777	positive regulation of cell cycle cytokinesis	4.081680e-3
GO:0042273	ribosomal large subunit biogenesis	4.097408e-3
GO:0009132	nucleoside diphosphate metabolic process	4.225524e-3
GO:0048205	COPI coating of Golgi vesicle	4.245121e-3
GO:0006432	phenylalanyl-tRNA aminoacylation	4.250486e-3
GO:0010477	response to sulfur dioxide	4.311811e-3
GO:0033577	protein glycosylation in endoplasmic reticulum	4.311811e-3
GO:0046038	GMP catabolic process	4.311811e-3
GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	4.311811e-3
GO:0006711	estrogen catabolic process	4.311811e-3
GO:0006235	dTTP biosynthetic process	4.311811e-3
GO:0002457	T cell antigen processing and presentation	4.311811e-3
GO:0000088	mitotic prophase	4.311811e-3
GO:0006178	guanine salvage	4.311811e-3
GO:0051572	negative regulation of histone H3-K4 methylation	4.370771e-3
GO:0051096	positive regulation of helicase activity	4.370771e-3
GO:0009648	photoperiodism	4.370771e-3
GO:0010742	macrophage derived foam cell differentiation	4.389820e-3
GO:0009200	deoxyribonucleoside triphosphate metabolic process	4.474389e-3
GO:0051955	regulation of amino acid transport	4.482507e-3
GO:0043415	positive regulation of skeletal muscle tissue regeneration	4.661453e-3
GO:0006533	aspartate catabolic process	4.661453e-3
GO:0009886	post-embryonic morphogenesis	4.696439e-3
GO:0006900	membrane budding	4.814563e-3
GO:0032425	positive regulation of mismatch repair	4.822008e-3
GO:0007030	Golgi organization	4.892758e-3
GO:0044339	canonical Wnt receptor signaling pathway involved in osteoblast differentiation	5.047283e-3
GO:0044338	canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation	5.047283e-3
GO:0019242	methylglyoxal biosynthetic process	5.047283e-3
GO:0035269	protein O-linked mannosylation	5.047283e-3
GO:0030309	poly-N-acetyllactosamine metabolic process	5.148690e-3
GO:0006408	snRNA export from nucleus	5.148690e-3
GO:0070245	positive regulation of thymocyte apoptosis	5.193415e-3
GO:0008617	guanosine metabolic process	5.223587e-3
GO:0033484	nitric oxide homeostasis	5.223587e-3
GO:0035562	negative regulation of chromatin binding	5.281506e-3
GO:0032298	positive regulation of DNA-dependent DNA replication initiation	5.281506e-3
GO:0072329	monocarboxylic acid catabolic process	5.299291e-3
GO:0001835	blastocyst hatching	5.305166e-3
GO:0042226	interleukin-6 biosynthetic process	5.330950e-3
GO:0006189	'de novo' IMP biosynthetic process	5.330950e-3
GO:0030071	regulation of mitotic metaphase/anaphase transition	5.337129e-3
GO:0035883	enteroendocrine cell differentiation	5.415331e-3
GO:0051329	interphase of mitotic cell cycle	5.430548e-3
GO:0060765	regulation of androgen receptor signaling pathway	5.500944e-3
GO:2000108	positive regulation of leukocyte apoptosis	5.525723e-3
GO:0071283	cellular response to iron(III) ion	5.578884e-3
GO:0060623	regulation of chromosome condensation	5.578884e-3
GO:2000009	negative regulation of protein localization at cell surface	5.578884e-3
GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	5.578884e-3
GO:0046380	N-acetylneuraminate biosynthetic process	5.578884e-3
GO:0046680	response to DDT	5.578884e-3
GO:0060766	negative regulation of androgen receptor signaling pathway	5.998398e-3
GO:0043414	macromolecule methylation	6.005740e-3
GO:0016241	regulation of macroautophagy	6.071527e-3
GO:0006344	maintenance of chromatin silencing	6.097797e-3
GO:0031575	mitotic cell cycle G1/S transition checkpoint	6.164695e-3
GO:0045839	negative regulation of mitosis	6.242943e-3
GO:0018027	peptidyl-lysine dimethylation	6.258467e-3
GO:0000389	nuclear mRNA 3'-splice site recognition	6.258467e-3
GO:0007091	mitotic metaphase/anaphase transition	6.289027e-3
GO:0034976	response to endoplasmic reticulum stress	6.608848e-3
GO:0042758	long-chain fatty acid catabolic process	6.697417e-3
GO:0032417	positive regulation of sodium:hydrogen antiporter activity	6.697417e-3
GO:0042413	carnitine catabolic process	6.697417e-3
GO:0044249	cellular biosynthetic process	6.697655e-3
GO:0018022	peptidyl-lysine methylation	6.753484e-3
GO:0007051	spindle organization	6.836755e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0034660	ncRNA metabolic process	1.896045e-32
GO:0034470	ncRNA processing	3.080630e-31
GO:0006396	RNA processing	2.551118e-30
GO:0030488	tRNA methylation	6.111037e-24
GO:0071843	cellular component biogenesis at cellular level	6.461909e-23
GO:0006400	tRNA modification	7.177988e-23
GO:0006399	tRNA metabolic process	1.251873e-22
GO:0008033	tRNA processing	7.770386e-22
GO:0022613	ribonucleoprotein complex biogenesis	1.936211e-21
GO:0042254	ribosome biogenesis	6.070640e-21
GO:0009451	RNA modification	2.081673e-19
GO:0001510	RNA methylation	1.019965e-15
GO:0016072	rRNA metabolic process	4.326297e-15
GO:0006364	rRNA processing	1.808106e-13
GO:0008380	RNA splicing	3.897143e-11
GO:0006412	translation	5.258787e-11
GO:0006397	mRNA processing	1.769904e-9
GO:0046605	regulation of centrosome cycle	8.468225e-9
GO:0046599	regulation of centriole replication	1.080866e-8
GO:0018293	protein-FAD linkage	3.039901e-8
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	3.039901e-8
GO:0006974	response to DNA damage stimulus	5.521243e-8
GO:0010467	gene expression	6.072565e-8
GO:0010824	regulation of centrosome duplication	7.928821e-8
GO:0016071	mRNA metabolic process	1.621431e-7
GO:0001522	pseudouridine synthesis	1.901967e-7
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	5.539979e-7
GO:0022417	protein maturation by protein folding	5.539979e-7
GO:0044260	cellular macromolecule metabolic process	7.498684e-7
GO:0090231	regulation of spindle checkpoint	9.687111e-7
GO:0006099	tricarboxylic acid cycle	1.338609e-6
GO:0046356	acetyl-CoA catabolic process	1.560898e-6
GO:0072368	regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter	1.660308e-6
GO:0000492	box C/D snoRNP assembly	1.660308e-6
GO:0072362	regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter	1.660308e-6
GO:0007076	mitotic chromosome condensation	1.708634e-6
GO:0050658	RNA transport	2.843115e-6
GO:0006189	'de novo' IMP biosynthetic process	2.853599e-6
GO:0015931	nucleobase-containing compound transport	4.029696e-6
GO:0071168	protein localization to chromatin	4.226698e-6
GO:0006139	nucleobase-containing compound metabolic process	5.097301e-6
GO:0007059	chromosome segregation	5.704648e-6
GO:0007520	myoblast fusion	5.967838e-6
GO:0090304	nucleic acid metabolic process	7.620691e-6
GO:0045454	cell redox homeostasis	7.953292e-6
GO:0045585	positive regulation of cytotoxic T cell differentiation	9.099700e-6
GO:0008216	spermidine metabolic process	9.099700e-6
GO:0035372	protein localization to microtubule	9.172438e-6
GO:0046600	negative regulation of centriole replication	9.613019e-6
GO:0022007	convergent extension involved in neural plate elongation	1.019597e-5
GO:0009109	coenzyme catabolic process	1.216672e-5
GO:0006403	RNA localization	1.248552e-5
GO:0000087	M phase of mitotic cell cycle	1.284976e-5
GO:0034641	cellular nitrogen compound metabolic process	1.367899e-5
GO:0070584	mitochondrion morphogenesis	1.431949e-5
GO:0071169	establishment of protein localization to chromatin	1.453423e-5
GO:0032853	positive regulation of Ran GTPase activity	1.453423e-5
GO:0043632	modification-dependent macromolecule catabolic process	1.792156e-5
GO:0032071	regulation of endodeoxyribonuclease activity	1.866463e-5
GO:0045116	protein neddylation	1.904848e-5
GO:0000768	syncytium formation by plasma membrane fusion	1.983892e-5
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	2.004487e-5
GO:0001678	cellular glucose homeostasis	2.256898e-5
GO:0031023	microtubule organizing center organization	2.329094e-5
GO:0006511	ubiquitin-dependent protein catabolic process	2.581119e-5
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	2.684860e-5
GO:0007067	mitosis	2.704662e-5
GO:0006297	nucleotide-excision repair, DNA gap filling	2.708437e-5
GO:0022900	electron transport chain	2.961894e-5
GO:0019941	modification-dependent protein catabolic process	3.187421e-5
GO:0014816	satellite cell differentiation	3.198299e-5
GO:0032922	circadian regulation of gene expression	3.293833e-5
GO:0033108	mitochondrial respiratory chain complex assembly	3.511196e-5
GO:0042773	ATP synthesis coupled electron transport	3.757273e-5
GO:0006949	syncytium formation	3.784054e-5
GO:0051276	chromosome organization	4.261357e-5
GO:0051603	proteolysis involved in cellular protein catabolic process	4.453474e-5
GO:0048285	organelle fission	4.483896e-5
GO:0007049	cell cycle	5.077531e-5
GO:0015986	ATP synthesis coupled proton transport	5.666161e-5
GO:0033566	gamma-tubulin complex localization	5.722664e-5
GO:0006102	isocitrate metabolic process	6.952302e-5
GO:0032007	negative regulation of TOR signaling cascade	7.017599e-5
GO:0071826	ribonucleoprotein complex subunit organization	7.362809e-5
GO:0006281	DNA repair	7.969435e-5
GO:0051028	mRNA transport	8.557385e-5
GO:0061034	olfactory bulb mitral cell layer development	8.696090e-5
GO:0051187	cofactor catabolic process	8.731435e-5
GO:0046952	ketone body catabolic process	9.235809e-5
GO:0051176	positive regulation of sulfur metabolic process	1.025696e-4
GO:0022618	ribonucleoprotein complex assembly	1.062803e-4
GO:0009060	aerobic respiration	1.063455e-4
GO:0000027	ribosomal large subunit assembly	1.087536e-4
GO:0032070	regulation of deoxyribonuclease activity	1.090089e-4
GO:0044237	cellular metabolic process	1.122762e-4
GO:0016073	snRNA metabolic process	1.154563e-4
GO:0000070	mitotic sister chromatid segregation	1.170763e-4
GO:0071333	cellular response to glucose stimulus	1.227491e-4
GO:0032200	telomere organization	1.239795e-4
GO:0030163	protein catabolic process	1.254861e-4
GO:0051297	centrosome organization	1.367425e-4
GO:0031365	N-terminal protein amino acid modification	1.388909e-4
GO:0044257	cellular protein catabolic process	1.411961e-4
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	1.418570e-4
GO:0051661	maintenance of centrosome location	1.418570e-4
GO:0006922	cleavage of lamin	1.418570e-4
GO:0032078	negative regulation of endodeoxyribonuclease activity	1.418570e-4
GO:0016075	rRNA catabolic process	1.478285e-4
GO:0010498	proteasomal protein catabolic process	1.496656e-4
GO:0006603	phosphocreatine metabolic process	1.514129e-4
GO:0006807	nitrogen compound metabolic process	1.577535e-4
GO:0000819	sister chromatid segregation	1.643253e-4
GO:0006259	DNA metabolic process	1.701869e-4
GO:0072655	establishment of protein localization in mitochondrion	1.710729e-4
GO:0080164	regulation of nitric oxide metabolic process	1.744457e-4
GO:0043968	histone H2A acetylation	1.750563e-4
GO:0031577	spindle checkpoint	2.113318e-4
GO:0006268	DNA unwinding involved in replication	2.300444e-4
GO:0045333	cellular respiration	2.385140e-4
GO:0000279	M phase	2.474273e-4
GO:0006457	protein folding	2.610630e-4
GO:0016074	snoRNA metabolic process	2.685116e-4
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	2.730322e-4
GO:0001840	neural plate development	2.802573e-4
GO:0071103	DNA conformation change	2.805532e-4
GO:0006497	protein lipidation	2.820736e-4
GO:0060059	embryonic retina morphogenesis in camera-type eye	3.432085e-4
GO:0006119	oxidative phosphorylation	3.432085e-4
GO:0006560	proline metabolic process	3.433519e-4
GO:0043538	regulation of actin phosphorylation	3.443021e-4
GO:0042384	cilium assembly	3.528515e-4
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	3.702749e-4
GO:0090179	planar cell polarity pathway involved in neural tube closure	4.109848e-4
GO:0006598	polyamine catabolic process	4.251316e-4
GO:0042775	mitochondrial ATP synthesis coupled electron transport	4.266481e-4
GO:0015992	proton transport	4.294994e-4
GO:0000375	RNA splicing, via transesterification reactions	4.302173e-4
GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	4.344487e-4
GO:0006391	transcription initiation from mitochondrial promoter	4.344487e-4
GO:0044085	cellular component biogenesis	4.400914e-4
GO:0022038	corpus callosum development	4.475614e-4
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	4.613138e-4
GO:0000398	nuclear mRNA splicing, via spliceosome	5.412559e-4
GO:0006818	hydrogen transport	5.642992e-4
GO:0032069	regulation of nuclease activity	5.765663e-4
GO:0016180	snRNA processing	5.852475e-4
GO:0006188	IMP biosynthetic process	5.877610e-4
GO:0048668	collateral sprouting	6.120103e-4
GO:0006733	oxidoreduction coenzyme metabolic process	6.290661e-4
GO:0070585	protein localization in mitochondrion	6.334043e-4
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	6.352412e-4
GO:0030149	sphingolipid catabolic process	6.440743e-4
GO:0060982	coronary artery morphogenesis	6.922937e-4
GO:0008054	cyclin catabolic process	7.019039e-4
GO:0034498	early endosome to Golgi transport	7.092126e-4
GO:0046314	phosphocreatine biosynthetic process	7.337781e-4
GO:0050668	positive regulation of homocysteine metabolic process	7.337781e-4
GO:0045963	negative regulation of dopamine metabolic process	7.337781e-4
GO:0031914	negative regulation of synaptic plasticity	7.337781e-4
GO:0006595	polyamine metabolic process	7.542635e-4
GO:0001839	neural plate morphogenesis	7.542635e-4
GO:0044248	cellular catabolic process	7.615860e-4
GO:0000723	telomere maintenance	7.720262e-4
GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	7.906825e-4
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion	7.920490e-4
GO:0034661	ncRNA catabolic process	7.932413e-4
GO:0070925	organelle assembly	8.025122e-4
GO:0032508	DNA duplex unwinding	8.200287e-4
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	8.307644e-4
GO:0006474	N-terminal protein amino acid acetylation	8.577218e-4
GO:0000959	mitochondrial RNA metabolic process	8.577218e-4
GO:0034621	cellular macromolecular complex subunit organization	8.979859e-4
GO:0060983	epicardium-derived cardiac vascular smooth muscle cell differentiation	9.019868e-4
GO:0009143	nucleoside triphosphate catabolic process	9.470357e-4
GO:0060318	definitive erythrocyte differentiation	9.510902e-4
GO:0032006	regulation of TOR signaling cascade	9.644103e-4
GO:0071322	cellular response to carbohydrate stimulus	9.989312e-4
GO:0034622	cellular macromolecular complex assembly	1.006134e-3
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	1.009540e-3
GO:0006626	protein targeting to mitochondrion	1.042524e-3
GO:0018065	protein-cofactor linkage	1.063378e-3
GO:0022904	respiratory electron transport chain	1.081153e-3
GO:0009146	purine nucleoside triphosphate catabolic process	1.129592e-3
GO:0032392	DNA geometric change	1.131600e-3
GO:0000722	telomere maintenance via recombination	1.146844e-3
GO:0006931	substrate-dependent cell migration, cell attachment to substrate	1.175343e-3
GO:0006084	acetyl-CoA metabolic process	1.196752e-3
GO:0000278	mitotic cell cycle	1.231828e-3
GO:0051029	rRNA transport	1.253037e-3
GO:0072321	chaperone-mediated protein transport	1.266509e-3
GO:0035601	protein deacylation	1.306555e-3
GO:0006476	protein deacetylation	1.319068e-3
GO:0044340	canonical Wnt receptor signaling pathway involved in regulation of cell proliferation	1.371526e-3
GO:0006323	DNA packaging	1.386553e-3
GO:0071174	mitotic cell cycle spindle checkpoint	1.429689e-3
GO:0043048	dolichyl monophosphate biosynthetic process	1.518058e-3
GO:0030970	retrograde protein transport, ER to cytosol	1.545650e-3
GO:0072361	regulation of glycolysis by regulation of transcription from RNA polymerase II promoter	1.564927e-3
GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	1.564927e-3
GO:0006506	GPI anchor biosynthetic process	1.574452e-3
GO:0051131	chaperone-mediated protein complex assembly	1.684658e-3
GO:0045040	protein import into mitochondrial outer membrane	1.684658e-3
GO:0016322	neuron remodeling	1.688459e-3
GO:2000384	negative regulation of ectoderm development	1.740985e-3
GO:0016226	iron-sulfur cluster assembly	1.774954e-3
GO:0033129	positive regulation of histone phosphorylation	1.800675e-3
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	1.800675e-3
GO:0006418	tRNA aminoacylation for protein translation	1.863739e-3
GO:0072560	type B pancreatic cell maturation	1.923110e-3
GO:0003127	detection of nodal flow	1.923110e-3
GO:0009207	purine ribonucleoside triphosphate catabolic process	1.977438e-3
GO:0016070	RNA metabolic process	1.999393e-3
GO:0010458	exit from mitosis	2.132446e-3
GO:0002561	basophil degranulation	2.158640e-3
GO:0019046	reactivation of latent virus	2.158640e-3
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	2.185946e-3
GO:0035928	rRNA import into mitochondrion	2.185946e-3
GO:0006013	mannose metabolic process	2.264606e-3
GO:0046015	regulation of transcription by glucose	2.271367e-3
GO:0042396	phosphagen biosynthetic process	2.354107e-3
GO:0032981	mitochondrial respiratory chain complex I assembly	2.427003e-3
GO:0042402	cellular biogenic amine catabolic process	2.502632e-3
GO:0006505	GPI anchor metabolic process	2.550754e-3
GO:0022402	cell cycle process	2.570627e-3
GO:0021794	thalamus development	2.690851e-3
GO:0031848	protection from non-homologous end joining at telomere	3.017154e-3
GO:0034619	cellular chaperone-mediated protein complex assembly	3.033856e-3
GO:0051775	response to redox state	3.063837e-3
GO:0070368	positive regulation of hepatocyte differentiation	3.063837e-3
GO:0014028	notochord formation	3.063837e-3
GO:0006610	ribosomal protein import into nucleus	3.110604e-3
GO:0051289	protein homotetramerization	3.118047e-3
GO:0045749	negative regulation of S phase of mitotic cell cycle	3.176589e-3
GO:0045717	negative regulation of fatty acid biosynthetic process	3.355568e-3
GO:0007094	mitotic cell cycle spindle assembly checkpoint	3.520435e-3
GO:0065004	protein-DNA complex assembly	3.606277e-3
GO:0007090	regulation of S phase of mitotic cell cycle	3.751548e-3
GO:0042758	long-chain fatty acid catabolic process	3.791726e-3
GO:0042413	carnitine catabolic process	3.791726e-3
GO:0031643	positive regulation of myelination	3.791726e-3
GO:2000383	regulation of ectoderm development	4.056083e-3
GO:0015864	pyrimidine nucleoside transport	4.056083e-3
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	4.056083e-3
GO:0015862	uridine transport	4.074737e-3
GO:0007096	regulation of exit from mitosis	4.396525e-3
GO:0015780	nucleotide-sugar transport	4.396525e-3
GO:0071173	spindle assembly checkpoint	4.470586e-3
GO:0034421	post-translational protein acetylation	4.576825e-3
GO:0032074	negative regulation of nuclease activity	4.576825e-3
GO:0033572	transferrin transport	4.576825e-3
GO:0045724	positive regulation of flagellum assembly	4.577757e-3
GO:0045575	basophil activation	4.577757e-3
GO:0015966	diadenosine tetraphosphate biosynthetic process	4.577757e-3
GO:0045358	negative regulation of interferon-beta biosynthetic process	4.577757e-3
GO:0006184	GTP catabolic process	4.691264e-3
GO:0006734	NADH metabolic process	4.758280e-3
GO:0048935	peripheral nervous system neuron development	4.765362e-3
GO:0046039	GTP metabolic process	4.959388e-3
GO:0009437	carnitine metabolic process	4.972342e-3
GO:0008631	induction of apoptosis by oxidative stress	4.972342e-3
GO:0009154	purine ribonucleotide catabolic process	5.004621e-3
GO:0060620	regulation of cholesterol import	5.063577e-3
GO:0031627	telomeric loop formation	5.087666e-3
GO:0006562	proline catabolic process	5.087666e-3
GO:0018230	peptidyl-L-cysteine S-palmitoylation	5.087666e-3
GO:0046496	nicotinamide nucleotide metabolic process	5.129031e-3
GO:0060285	ciliary cell motility	5.211740e-3
GO:0055070	copper ion homeostasis	5.309571e-3
GO:0019362	pyridine nucleotide metabolic process	5.342321e-3
GO:0045769	negative regulation of asymmetric cell division	5.548896e-3
GO:0048213	Golgi vesicle prefusion complex stabilization	5.548896e-3
GO:0034346	positive regulation of type III interferon production	5.548896e-3
GO:0006683	galactosylceramide catabolic process	5.548896e-3
GO:0002542	Factor XII activation	5.548896e-3
GO:0070189	kynurenine metabolic process	5.862298e-3
GO:0033127	regulation of histone phosphorylation	6.043529e-3
GO:0071824	protein-DNA complex subunit organization	6.160805e-3
GO:0042158	lipoprotein biosynthetic process	6.450618e-3
GO:0006513	protein monoubiquitination	6.461520e-3
GO:0018279	protein N-linked glycosylation via asparagine	6.468907e-3
GO:0033261	regulation of S phase	6.525194e-3
GO:0000281	cytokinesis after mitosis	6.604421e-3
GO:0046416	D-amino acid metabolic process	6.617714e-3
GO:0045426	quinone cofactor biosynthetic process	6.912545e-3
GO:0060621	negative regulation of cholesterol import	6.942971e-3
GO:0032465	regulation of cytokinesis	6.973105e-3
GO:0007017	microtubule-based process	7.046979e-3
GO:0000380	alternative nuclear mRNA splicing, via spliceosome	7.061103e-3
GO:0006270	DNA-dependent DNA replication initiation	7.134481e-3
GO:0032204	regulation of telomere maintenance	7.928336e-3
GO:0046950	cellular ketone body metabolic process	7.970438e-3
GO:0060632	regulation of microtubule-based movement	8.151559e-3
GO:0045792	negative regulation of cell size	8.252165e-3
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	8.270595e-3
GO:0010897	negative regulation of triglyceride catabolic process	8.270595e-3
GO:0010987	negative regulation of high-density lipoprotein particle clearance	8.270595e-3
GO:0043497	regulation of protein heterodimerization activity	8.300629e-3
GO:0017196	N-terminal peptidyl-methionine acetylation	8.324750e-3
GO:0006258	UDP-glucose catabolic process	8.324750e-3
GO:0000963	mitochondrial RNA processing	8.324750e-3
GO:0031638	zymogen activation	8.346563e-3
GO:0009261	ribonucleotide catabolic process	8.453872e-3
GO:0061032	visceral serous pericardium development	8.595356e-3
GO:0051186	cofactor metabolic process	8.611871e-3
GO:0014010	Schwann cell proliferation	8.988491e-3
GO:0006172	ADP biosynthetic process	8.988491e-3
GO:0033205	cell cycle cytokinesis	9.193779e-3
GO:0035562	negative regulation of chromatin binding	9.245189e-3
GO:0035195	gene silencing by miRNA	9.257451e-3
GO:0001539	ciliary or flagellar motility	9.391072e-3
GO:2000078	positive regulation of type B pancreatic cell development	9.420254e-3
GO:0006685	sphingomyelin catabolic process	9.420254e-3
GO:0048007	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	9.420254e-3
GO:0035194	posttranscriptional gene silencing by RNA	9.505853e-3
GO:0065003	macromolecular complex assembly	9.529994e-3
GO:0010948	negative regulation of cell cycle process	9.581497e-3
GO:0015031	protein transport	9.666831e-3
GO:0090193	positive regulation of glomerulus development	9.746395e-3
GO:0000910	cytokinesis	9.806662e-3
GO:0009056	catabolic process	9.812637e-3
GO:0090381	regulation of heart induction	1.023437e-2
GO:0006260	DNA replication	1.040555e-2
GO:0019674	NAD metabolic process	1.040939e-2
GO:0022403	cell cycle phase	1.056335e-2
GO:0046434	organophosphate catabolic process	1.090262e-2
GO:0072594	establishment of protein localization to organelle	1.101334e-2
GO:0006325	chromatin organization	1.107090e-2
GO:0045793	positive regulation of cell size	1.108144e-2
GO:0009296	flagellum assembly	1.113771e-2
GO:0044265	cellular macromolecule catabolic process	1.113892e-2
GO:0072298	regulation of metanephric glomerulus development	1.115049e-2
GO:0090200	positive regulation of release of cytochrome c from mitochondria	1.125985e-2
GO:0009113	purine base biosynthetic process	1.144200e-2
GO:0046474	glycerophospholipid biosynthetic process	1.154847e-2
GO:0034551	mitochondrial respiratory chain complex III assembly	1.163968e-2
GO:0021540	corpus callosum morphogenesis	1.163968e-2
GO:0051660	establishment of centrosome localization	1.163968e-2
GO:0002508	central tolerance induction	1.163968e-2
GO:0008611	ether lipid biosynthetic process	1.163968e-2
GO:0002897	positive regulation of central B cell tolerance induction	1.163968e-2
GO:0006334	nucleosome assembly	1.185890e-2
GO:0051292	nuclear pore complex assembly	1.222161e-2
GO:0061084	negative regulation of protein refolding	1.222161e-2
GO:0010834	telomere maintenance via telomere shortening	1.222161e-2
GO:0006438	valyl-tRNA aminoacylation	1.222161e-2
GO:0046931	pore complex assembly	1.252874e-2
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	1.252874e-2
GO:0018206	peptidyl-methionine modification	1.253975e-2
GO:0010994	free ubiquitin chain polymerization	1.253975e-2
GO:0006289	nucleotide-excision repair	1.256864e-2
GO:0051684	maintenance of Golgi location	1.268417e-2
GO:0070899	mitochondrial tRNA wobble uridine modification	1.268417e-2
GO:0048239	negative regulation of DNA recombination at telomere	1.268417e-2
GO:0006430	lysyl-tRNA aminoacylation	1.268417e-2
GO:0006574	valine catabolic process	1.268417e-2
GO:0019484	beta-alanine catabolic process	1.268417e-2
GO:0006744	ubiquinone biosynthetic process	1.271984e-2
GO:0031536	positive regulation of exit from mitosis	1.316691e-2
GO:0035087	siRNA loading onto RISC involved in RNA interference	1.320954e-2
GO:0015980	energy derivation by oxidation of organic compounds	1.333293e-2
GO:0006390	transcription from mitochondrial promoter	1.340418e-2
GO:0032259	methylation	1.351826e-2
GO:0006650	glycerophospholipid metabolic process	1.361456e-2
GO:0070625	zymogen granule exocytosis	1.363103e-2
GO:0002158	osteoclast proliferation	1.363103e-2
GO:0051262	protein tetramerization	1.411612e-2
GO:0018345	protein palmitoylation	1.433501e-2
GO:0006302	double-strand break repair	1.447650e-2
GO:0019441	tryptophan catabolic process to kynurenine	1.453967e-2
GO:0006333	chromatin assembly or disassembly	1.460523e-2
GO:0045184	establishment of protein localization	1.490921e-2
GO:0002238	response to molecule of fungal origin	1.492407e-2
GO:0060271	cilium morphogenesis	1.505036e-2
GO:0045653	negative regulation of megakaryocyte differentiation	1.508583e-2
GO:0060298	positive regulation of sarcomere organization	1.518435e-2
GO:0007140	male meiosis	1.545867e-2
GO:0006098	pentose-phosphate shunt	1.554842e-2
GO:0009303	rRNA transcription	1.555734e-2
GO:0006537	glutamate biosynthetic process	1.557621e-2
GO:0010626	negative regulation of Schwann cell proliferation	1.557621e-2
GO:0019254	carnitine metabolic process, CoA-linked	1.557621e-2
GO:0006561	proline biosynthetic process	1.557621e-2
GO:0060026	convergent extension	1.561754e-2
GO:0061198	fungiform papilla formation	1.566315e-2
GO:0043543	protein acylation	1.568363e-2
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	1.572682e-2
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	1.575484e-2
GO:0042375	quinone cofactor metabolic process	1.576982e-2
GO:0006661	phosphatidylinositol biosynthetic process	1.581231e-2
GO:0071544	diphosphoinositol polyphosphate catabolic process	1.641750e-2
GO:0006498	N-terminal protein lipidation	1.657730e-2
GO:0070935	3'-UTR-mediated mRNA stabilization	1.657730e-2
GO:0003223	ventricular compact myocardium morphogenesis	1.657730e-2
GO:0003136	negative regulation of heart induction by canonical Wnt receptor signaling pathway	1.657730e-2
GO:0045931	positive regulation of mitotic cell cycle	1.721798e-2
GO:0033239	negative regulation of cellular amine metabolic process	1.728514e-2
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.728514e-2
GO:0014902	myotube differentiation	1.734317e-2
GO:0035507	regulation of myosin-light-chain-phosphatase activity	1.823129e-2
GO:0006651	diacylglycerol biosynthetic process	1.823129e-2
GO:0030091	protein repair	1.823129e-2
GO:0090192	regulation of glomerulus development	1.838993e-2
GO:0009264	deoxyribonucleotide catabolic process	1.849400e-2
GO:0061196	fungiform papilla development	1.849400e-2
GO:0072300	positive regulation of metanephric glomerulus development	1.849400e-2
GO:0034111	negative regulation of homotypic cell-cell adhesion	1.849400e-2
GO:0043414	macromolecule methylation	1.857027e-2
GO:0016574	histone ubiquitination	1.920774e-2
GO:0035584	calcium-mediated signaling using intracellular calcium source	1.953508e-2
GO:0006878	cellular copper ion homeostasis	1.954456e-2
GO:0010508	positive regulation of autophagy	1.999562e-2
GO:0035058	nonmotile primary cilium assembly	2.025469e-2
GO:0045017	glycerolipid biosynthetic process	2.046389e-2
GO:0070179	D-serine biosynthetic process	2.067583e-2
GO:0045919	positive regulation of cytolysis	2.067583e-2
GO:0008295	spermidine biosynthetic process	2.067583e-2
GO:0031497	chromatin assembly	2.072961e-2
GO:0051188	cofactor biosynthetic process	2.080701e-2
GO:0043320	natural killer cell degranulation	2.108906e-2
GO:0009204	deoxyribonucleoside triphosphate catabolic process	2.108906e-2
GO:0006195	purine nucleotide catabolic process	2.118889e-2
GO:0035564	regulation of kidney size	2.120963e-2
GO:0060492	lung induction	2.142722e-2
GO:0045014	negative regulation of transcription by glucose	2.168295e-2
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	2.168295e-2
GO:0032933	SREBP-mediated signaling pathway	2.177272e-2
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	2.177272e-2
GO:0046580	negative regulation of Ras protein signal transduction	2.230200e-2
GO:0009107	lipoate biosynthetic process	2.233784e-2
GO:0006437	tyrosyl-tRNA aminoacylation	2.233784e-2
GO:0072531	pyrimidine-containing compound transmembrane transport	2.239965e-2
GO:0006465	signal peptide processing	2.239965e-2
GO:0071638	negative regulation of monocyte chemotactic protein-1 production	2.320969e-2
GO:0065002	intracellular protein transmembrane transport	2.320969e-2
GO:2000429	negative regulation of neutrophil aggregation	2.320969e-2
GO:2000469	negative regulation of peroxidase activity	2.320969e-2
GO:0035726	common myeloid progenitor cell proliferation	2.320969e-2
GO:0043633	polyadenylation-dependent RNA catabolic process	2.320969e-2
GO:0032532	regulation of microvillus length	2.320969e-2
GO:0034725	DNA replication-dependent nucleosome disassembly	2.320969e-2
GO:0018202	peptidyl-histidine modification	2.337333e-2
GO:0000075	cell cycle checkpoint	2.344473e-2
GO:0043064	flagellum organization	2.411723e-2
GO:0015991	ATP hydrolysis coupled proton transport	2.417875e-2
GO:0034502	protein localization to chromosome	2.449371e-2
GO:0060789	hair follicle placode formation	2.450471e-2
GO:0009057	macromolecule catabolic process	2.529438e-2
GO:0051403	stress-activated MAPK cascade	2.534238e-2
GO:0042255	ribosome assembly	2.534728e-2
GO:0061002	negative regulation of dendritic spine morphogenesis	2.536188e-2
GO:2000015	regulation of determination of dorsal identity	2.561431e-2
GO:0008156	negative regulation of DNA replication	2.605561e-2
GO:0046514	ceramide catabolic process	2.664725e-2
GO:0002792	negative regulation of peptide secretion	2.705385e-2
GO:0042048	olfactory behavior	2.715073e-2
GO:0032682	negative regulation of chemokine production	2.715073e-2
GO:0009106	lipoate metabolic process	2.715073e-2
GO:0006732	coenzyme metabolic process	2.725116e-2
GO:0046676	negative regulation of insulin secretion	2.725822e-2
GO:0051983	regulation of chromosome segregation	2.819819e-2
GO:0045922	negative regulation of fatty acid metabolic process	2.819819e-2
GO:0034728	nucleosome organization	2.849384e-2
GO:0045351	type I interferon biosynthetic process	2.922472e-2
GO:0032205	negative regulation of telomere maintenance	2.922472e-2
GO:0051643	endoplasmic reticulum localization	2.945057e-2
GO:0019348	dolichol metabolic process	2.945057e-2
GO:0043170	macromolecule metabolic process	2.947770e-2
GO:0035803	egg coat formation	2.948335e-2
GO:0009217	purine deoxyribonucleoside triphosphate catabolic process	2.948335e-2
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	2.958335e-2
GO:0048320	axial mesoderm formation	2.958335e-2
GO:0010070	zygote asymmetric cell division	2.958335e-2
GO:0035621	ER to Golgi ceramide transport	2.958335e-2
GO:0070198	protein localization to chromosome, telomeric region	3.000424e-2
GO:0010982	regulation of high-density lipoprotein particle clearance	3.000424e-2
GO:2000043	regulation of cardiac cell fate specification	3.020268e-2
GO:0019673	GDP-mannose metabolic process	3.020268e-2
GO:2000602	regulation of interphase of mitotic cell cycle	3.035458e-2
GO:0007005	mitochondrion organization	3.121710e-2
GO:0090278	negative regulation of peptide hormone secretion	3.147823e-2
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	3.206495e-2
GO:0014067	negative regulation of phosphatidylinositol 3-kinase cascade	3.206495e-2
GO:0035518	histone H2A monoubiquitination	3.256444e-2
GO:0060029	convergent extension involved in organogenesis	3.262967e-2
GO:0034382	chylomicron remnant clearance	3.262967e-2
GO:0006091	generation of precursor metabolites and energy	3.264774e-2
GO:0051225	spindle assembly	3.301486e-2
GO:0000154	rRNA modification	3.361931e-2
GO:0014040	positive regulation of Schwann cell differentiation	3.379966e-2
GO:0006668	sphinganine-1-phosphate metabolic process	3.379966e-2
GO:0001881	receptor recycling	3.379966e-2
GO:0000076	DNA replication checkpoint	3.379966e-2
GO:0051668	localization within membrane	3.454260e-2
GO:0003341	cilium movement	3.489249e-2
GO:0006344	maintenance of chromatin silencing	3.489249e-2
GO:0032446	protein modification by small protein conjugation	3.492385e-2
GO:0006986	response to unfolded protein	3.510519e-2
GO:0006663	platelet activating factor biosynthetic process	3.548755e-2
GO:0035566	regulation of metanephros size	3.548755e-2
GO:0042268	regulation of cytolysis	3.564082e-2