Novel motif:36

name:	motif36_AAGGAGRAN

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0007522	visceral muscle development	6.282301e-20
GO:0055009	atrial cardiac muscle tissue morphogenesis	1.543557e-19
GO:0007512	adult heart development	5.169555e-15
GO:0003009	skeletal muscle contraction	1.965885e-13
GO:0045110	intermediate filament bundle assembly	6.990440e-11
GO:0033693	neurofilament bundle assembly	2.338699e-9
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	2.725703e-9
GO:0045109	intermediate filament organization	3.401610e-9
GO:0003230	cardiac atrium development	3.500610e-9
GO:0003209	cardiac atrium morphogenesis	4.651267e-9
GO:0048259	regulation of receptor-mediated endocytosis	5.050851e-9
GO:0030100	regulation of endocytosis	5.711508e-9
GO:0055010	ventricular cardiac muscle tissue morphogenesis	5.765427e-9
GO:0042137	sequestering of neurotransmitter	9.150888e-9
GO:0007379	segment specification	1.791383e-8
GO:0003229	ventricular cardiac muscle tissue development	2.789164e-8
GO:0045806	negative regulation of endocytosis	4.949216e-8
GO:0051298	centrosome duplication	9.036162e-8
GO:0048260	positive regulation of receptor-mediated endocytosis	1.013511e-7
GO:0050804	regulation of synaptic transmission	1.445084e-7
GO:0045103	intermediate filament-based process	5.133676e-7
GO:0044341	sodium-dependent phosphate transport	6.528765e-7
GO:0006098	pentose-phosphate shunt	8.276771e-7
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	1.386515e-6
GO:0010625	positive regulation of Schwann cell proliferation	1.426508e-6
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	1.430754e-6
GO:0002027	regulation of heart rate	1.462739e-6
GO:0060696	regulation of phospholipid catabolic process	1.542567e-6
GO:0032425	positive regulation of mismatch repair	1.684913e-6
GO:0002889	regulation of immunoglobulin mediated immune response	1.892647e-6
GO:0002712	regulation of B cell mediated immunity	2.175094e-6
GO:0071316	cellular response to nicotine	2.222914e-6
GO:0006739	NADP metabolic process	2.481594e-6
GO:0014028	notochord formation	2.495866e-6
GO:0043462	regulation of ATPase activity	2.604227e-6
GO:0009712	catechol-containing compound metabolic process	2.758071e-6
GO:0006584	catecholamine metabolic process	3.554351e-6
GO:0002026	regulation of the force of heart contraction	3.902641e-6
GO:0015742	alpha-ketoglutarate transport	4.345924e-6
GO:0051293	establishment of spindle localization	5.032549e-6
GO:0010984	regulation of lipoprotein particle clearance	5.493763e-6
GO:0002921	negative regulation of humoral immune response	6.099089e-6
GO:0002251	organ or tissue specific immune response	7.018586e-6
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	7.154450e-6
GO:0040001	establishment of mitotic spindle localization	7.820782e-6
GO:0044057	regulation of system process	7.828585e-6
GO:0048167	regulation of synaptic plasticity	8.341355e-6
GO:0045104	intermediate filament cytoskeleton organization	8.475221e-6
GO:0031444	slow-twitch skeletal muscle fiber contraction	8.585026e-6
GO:0042415	norepinephrine metabolic process	9.125881e-6
GO:0060627	regulation of vesicle-mediated transport	1.327928e-5
GO:2000253	positive regulation of feeding behavior	1.453374e-5
GO:2000507	positive regulation of energy homeostasis	1.453374e-5
GO:0000132	establishment of mitotic spindle orientation	1.584658e-5
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	1.689673e-5
GO:0002037	negative regulation of L-glutamate transport	1.743587e-5
GO:0045994	positive regulation of translational initiation by iron	1.743587e-5
GO:0035881	amacrine cell differentiation	1.900778e-5
GO:0048332	mesoderm morphogenesis	1.927198e-5
GO:0002036	regulation of L-glutamate transport	1.934175e-5
GO:0042220	response to cocaine	1.969819e-5
GO:0051956	negative regulation of amino acid transport	2.013605e-5
GO:0015760	glucose-6-phosphate transport	2.056522e-5
GO:0000302	response to reactive oxygen species	2.090430e-5
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	2.130659e-5
GO:0032933	SREBP-mediated signaling pathway	2.135460e-5
GO:0006740	NADPH regeneration	2.166228e-5
GO:0010735	positive regulation of transcription via serum response element binding	2.200492e-5
GO:0032796	uropod organization	2.238291e-5
GO:0046015	regulation of transcription by glucose	2.238291e-5
GO:0032846	positive regulation of homeostatic process	2.273305e-5
GO:0032423	regulation of mismatch repair	2.424676e-5
GO:0010867	positive regulation of triglyceride biosynthetic process	2.483823e-5
GO:0071407	cellular response to organic cyclic compound	2.665294e-5
GO:0006447	regulation of translational initiation by iron	2.801429e-5
GO:0001707	mesoderm formation	3.007439e-5
GO:0006620	posttranslational protein targeting to membrane	3.008829e-5
GO:0070309	lens fiber cell morphogenesis	3.159191e-5
GO:0010985	negative regulation of lipoprotein particle clearance	3.303967e-5
GO:0030826	regulation of cGMP biosynthetic process	3.326053e-5
GO:0000414	regulation of histone H3-K36 methylation	3.353098e-5
GO:0045717	negative regulation of fatty acid biosynthetic process	3.365394e-5
GO:0048251	elastic fiber assembly	3.769080e-5
GO:0051955	regulation of amino acid transport	3.801456e-5
GO:0010900	negative regulation of phosphatidylcholine catabolic process	3.874035e-5
GO:0014910	regulation of smooth muscle cell migration	4.065350e-5
GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	4.420099e-5
GO:0021562	vestibulocochlear nerve development	4.527995e-5
GO:0071712	ER-associated misfolded protein catabolic process	4.910862e-5
GO:0034378	chylomicron assembly	6.173406e-5
GO:0051126	negative regulation of actin nucleation	6.173406e-5
GO:0050881	musculoskeletal movement	6.231241e-5
GO:0051569	regulation of histone H3-K4 methylation	6.386584e-5
GO:0051971	positive regulation of transmission of nerve impulse	6.437961e-5
GO:0007616	long-term memory	6.496942e-5
GO:0060035	notochord cell development	6.635528e-5
GO:0031296	B cell costimulation	6.635528e-5
GO:0045471	response to ethanol	6.678932e-5
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	6.801047e-5
GO:0002021	response to dietary excess	7.267669e-5
GO:0006939	smooth muscle contraction	7.485069e-5
GO:0050806	positive regulation of synaptic transmission	7.757797e-5
GO:0007569	cell aging	7.799506e-5
GO:0030844	positive regulation of intermediate filament depolymerization	8.095207e-5
GO:0003231	cardiac ventricle development	8.133411e-5
GO:0006936	muscle contraction	8.894861e-5
GO:0032862	activation of Rho GTPase activity	9.457498e-5
GO:0085029	extracellular matrix assembly	9.457498e-5
GO:0002227	innate immune response in mucosa	9.817433e-5
GO:0048008	platelet-derived growth factor receptor signaling pathway	1.004927e-4
GO:0042823	pyridoxal phosphate biosynthetic process	1.145705e-4
GO:0060561	apoptosis involved in morphogenesis	1.196325e-4
GO:0051054	positive regulation of DNA metabolic process	1.197213e-4
GO:0010664	negative regulation of striated muscle cell apoptosis	1.201054e-4
GO:0071392	cellular response to estradiol stimulus	1.274189e-4
GO:0003206	cardiac chamber morphogenesis	1.280118e-4
GO:0019896	axon transport of mitochondrion	1.388224e-4
GO:2000505	regulation of energy homeostasis	1.446323e-4
GO:0045136	development of secondary sexual characteristics	1.464770e-4
GO:0001808	negative regulation of type IV hypersensitivity	1.541236e-4
GO:0042538	hyperosmotic salinity response	1.596543e-4
GO:0032792	negative regulation of CREB transcription factor activity	1.621582e-4
GO:0015851	nucleobase transport	1.649029e-4
GO:0050909	sensory perception of taste	1.676963e-4
GO:0042696	menarche	1.735569e-4
GO:0048598	embryonic morphogenesis	1.746390e-4
GO:2000278	regulation of DNA biosynthetic process	1.781639e-4
GO:0007613	memory	1.786542e-4
GO:0035105	sterol regulatory element binding protein import into nucleus	1.832195e-4
GO:0003002	regionalization	1.852486e-4
GO:0003205	cardiac chamber development	1.897415e-4
GO:0009790	embryo development	1.913084e-4
GO:0048168	regulation of neuronal synaptic plasticity	2.014218e-4
GO:0055012	ventricular cardiac muscle cell differentiation	2.162213e-4
GO:0071624	positive regulation of granulocyte chemotaxis	2.248102e-4
GO:0050829	defense response to Gram-negative bacterium	2.278570e-4
GO:0050764	regulation of phagocytosis	2.288013e-4
GO:0061048	negative regulation of branching involved in lung morphogenesis	2.320449e-4
GO:0060676	ureteric bud formation	2.338370e-4
GO:0046543	development of secondary female sexual characteristics	2.372388e-4
GO:0051130	positive regulation of cellular component organization	2.387414e-4
GO:0051125	regulation of actin nucleation	2.471344e-4
GO:0007098	centrosome cycle	2.495753e-4
GO:0002920	regulation of humoral immune response	2.532711e-4
GO:0006463	steroid hormone receptor complex assembly	2.548125e-4
GO:0002676	regulation of chronic inflammatory response	2.612619e-4
GO:0045807	positive regulation of endocytosis	2.619680e-4
GO:0090398	cellular senescence	2.664573e-4
GO:0090400	stress-induced premature senescence	2.665639e-4
GO:0009450	gamma-aminobutyric acid catabolic process	2.679305e-4
GO:0043270	positive regulation of ion transport	2.764290e-4
GO:0019086	late viral mRNA transcription	2.768022e-4
GO:0060313	negative regulation of blood vessel remodeling	2.787176e-4
GO:0060311	negative regulation of elastin catabolic process	2.787176e-4
GO:0010703	negative regulation of histolysis	2.787176e-4
GO:0010711	negative regulation of collagen catabolic process	2.787176e-4
GO:0003208	cardiac ventricle morphogenesis	2.927512e-4
GO:0030010	establishment of cell polarity	2.958022e-4
GO:2000097	regulation of smooth muscle cell-matrix adhesion	2.963217e-4
GO:0001704	formation of primary germ layer	3.017304e-4
GO:0031536	positive regulation of exit from mitosis	3.255265e-4
GO:2000098	negative regulation of smooth muscle cell-matrix adhesion	3.295627e-4
GO:0071258	cellular response to gravity	3.295627e-4
GO:0035491	positive regulation of leukotriene production involved in inflammatory response	3.295627e-4
GO:0061044	negative regulation of vascular wound healing	3.295627e-4
GO:0071312	cellular response to alkaloid	3.416312e-4
GO:0019321	pentose metabolic process	3.477401e-4
GO:0051297	centrosome organization	3.518719e-4
GO:0019693	ribose phosphate metabolic process	3.572678e-4
GO:0043084	penile erection	3.575813e-4
GO:0050830	defense response to Gram-positive bacterium	3.723140e-4
GO:0018198	peptidyl-cysteine modification	3.732602e-4
GO:0001757	somite specification	3.762068e-4
GO:0050765	negative regulation of phagocytosis	4.088319e-4
GO:0051588	regulation of neurotransmitter transport	4.165993e-4
GO:0034389	lipid particle organization	4.239699e-4
GO:0008089	anterograde axon cargo transport	4.253943e-4
GO:0061143	alveolar primary septum development	4.291440e-4
GO:0044342	type B pancreatic cell proliferation	4.291440e-4
GO:0010918	positive regulation of mitochondrial membrane potential	4.291440e-4
GO:0015680	intracellular copper ion transport	4.291440e-4
GO:0002891	positive regulation of immunoglobulin mediated immune response	4.406480e-4
GO:0007612	learning	4.614899e-4
GO:0046732	active induction of host immune response by virus	4.654374e-4
GO:0033601	positive regulation of mammary gland epithelial cell proliferation	4.679221e-4
GO:0002385	mucosal immune response	4.778394e-4
GO:0045922	negative regulation of fatty acid metabolic process	4.835430e-4
GO:0009952	anterior/posterior pattern specification	4.903416e-4
GO:0015866	ADP transport	5.024930e-4
GO:0007589	body fluid secretion	5.025860e-4
GO:0042304	regulation of fatty acid biosynthetic process	5.358223e-4
GO:0002678	positive regulation of chronic inflammatory response	5.456957e-4
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	5.522916e-4
GO:0034114	regulation of heterotypic cell-cell adhesion	5.522916e-4
GO:0032274	gonadotropin secretion	5.561647e-4
GO:0010713	negative regulation of collagen metabolic process	5.793616e-4
GO:0010523	negative regulation of calcium ion transport into cytosol	5.818768e-4
GO:0006112	energy reserve metabolic process	5.924527e-4
GO:0050890	cognition	6.120939e-4
GO:0060052	neurofilament cytoskeleton organization	6.133065e-4
GO:0090207	regulation of triglyceride metabolic process	6.246137e-4
GO:0035606	peptidyl-cysteine S-trans-nitrosylation	6.272069e-4
GO:0042447	hormone catabolic process	6.321615e-4
GO:0032863	activation of Rac GTPase activity	6.519615e-4
GO:0045299	otolith mineralization	6.736957e-4
GO:0010866	regulation of triglyceride biosynthetic process	6.818633e-4
GO:0060123	regulation of growth hormone secretion	6.998927e-4
GO:0021766	hippocampus development	7.013633e-4
GO:0050432	catecholamine secretion	7.406642e-4
GO:0046341	CDP-diacylglycerol metabolic process	7.417394e-4
GO:0001807	regulation of type IV hypersensitivity	7.417394e-4
GO:0048680	positive regulation of axon regeneration	7.432150e-4
GO:0060252	positive regulation of glial cell proliferation	7.668088e-4
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	7.803216e-4
GO:2000210	positive regulation of anoikis	8.047667e-4
GO:0032780	negative regulation of ATPase activity	8.140842e-4
GO:0021528	commissural neuron differentiation in spinal cord	8.186507e-4
GO:2000303	regulation of ceramide biosynthetic process	8.284805e-4
GO:0009052	pentose-phosphate shunt, non-oxidative branch	8.328421e-4
GO:0031646	positive regulation of neurological system process	8.753744e-4
GO:2000491	positive regulation of hepatic stellate cell activation	9.028298e-4
GO:0009651	response to salt stress	9.095721e-4
GO:0071394	cellular response to testosterone stimulus	9.147771e-4
GO:0090208	positive regulation of triglyceride metabolic process	9.154655e-4
GO:0070904	transepithelial L-ascorbic acid transport	9.382649e-4
GO:0060996	dendritic spine development	9.605686e-4
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	9.749272e-4
GO:0022038	corpus callosum development	9.768225e-4
GO:0048261	negative regulation of receptor-mediated endocytosis	1.013208e-3
GO:0003278	apoptosis involved in heart morphogenesis	1.019523e-3
GO:0018277	protein deamination	1.022264e-3
GO:0046884	follicle-stimulating hormone secretion	1.064914e-3
GO:0032275	luteinizing hormone secretion	1.064914e-3
GO:0000416	positive regulation of histone H3-K36 methylation	1.064914e-3
GO:0060430	lung saccule development	1.083454e-3
GO:0060124	positive regulation of growth hormone secretion	1.105808e-3
GO:0051532	regulation of NFAT protein import into nucleus	1.113415e-3
GO:0015853	adenine transport	1.123966e-3
GO:0043243	positive regulation of protein complex disassembly	1.195618e-3
GO:0060992	response to fungicide	1.205450e-3
GO:0035307	positive regulation of protein dephosphorylation	1.205450e-3
GO:0060612	adipose tissue development	1.214856e-3
GO:0021570	rhombomere 4 development	1.232465e-3
GO:0051004	regulation of lipoprotein lipase activity	1.245246e-3
GO:0010561	negative regulation of glycoprotein biosynthetic process	1.246570e-3
GO:0010524	positive regulation of calcium ion transport into cytosol	1.252546e-3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	1.258867e-3
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	1.258867e-3
GO:0009817	defense response to fungus, incompatible interaction	1.258867e-3
GO:0010667	negative regulation of cardiac muscle cell apoptosis	1.270804e-3
GO:0042766	nucleosome mobilization	1.275470e-3
GO:2000304	positive regulation of ceramide biosynthetic process	1.318507e-3
GO:0048839	inner ear development	1.319497e-3
GO:0048630	skeletal muscle tissue growth	1.319528e-3
GO:0035066	positive regulation of histone acetylation	1.347729e-3
GO:0071287	cellular response to manganese ion	1.355555e-3
GO:0070633	transepithelial transport	1.385417e-3
GO:0002513	tolerance induction to self antigen	1.387598e-3
GO:0003012	muscle system process	1.389189e-3
GO:0007635	chemosensory behavior	1.419928e-3
GO:0007611	learning or memory	1.424055e-3
GO:0072081	specification of nephron tubule identity	1.429207e-3
GO:0006927	transformed cell apoptosis	1.463101e-3
GO:0070120	ciliary neurotrophic factor-mediated signaling pathway	1.467158e-3
GO:0010350	cellular response to magnesium starvation	1.484654e-3
GO:0021919	BMP signaling pathway involved in spinal cord dorsal/ventral patterning	1.521201e-3
GO:0009235	cobalamin metabolic process	1.521201e-3
GO:0070625	zymogen granule exocytosis	1.562200e-3
GO:0014005	microglia development	1.562200e-3
GO:0010225	response to UV-C	1.569312e-3
GO:0050912	detection of chemical stimulus involved in sensory perception of taste	1.615611e-3
GO:0061302	smooth muscle cell-matrix adhesion	1.615850e-3
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	1.615850e-3
GO:0048752	semicircular canal morphogenesis	1.626003e-3
GO:0021508	floor plate formation	1.633403e-3
GO:0071549	cellular response to dexamethasone stimulus	1.653469e-3
GO:0035417	negative regulation of mitotic prometaphase	1.655532e-3
GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning	1.655532e-3
GO:0002502	peptide antigen assembly with MHC class I protein complex	1.655532e-3
GO:0033504	floor plate development	1.670108e-3
GO:0006513	protein monoubiquitination	1.684363e-3
GO:0006685	sphingomyelin catabolic process	1.729609e-3
GO:0010765	positive regulation of sodium ion transport	1.764087e-3
GO:0060997	dendritic spine morphogenesis	1.780028e-3
GO:0006525	arginine metabolic process	1.817735e-3
GO:0035094	response to nicotine	1.875500e-3
GO:0043279	response to alkaloid	1.889416e-3
GO:0061043	regulation of vascular wound healing	1.979371e-3
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	1.979371e-3
GO:0008306	associative learning	2.002909e-3
GO:0030853	negative regulation of granulocyte differentiation	2.022172e-3
GO:0048705	skeletal system morphogenesis	2.042897e-3
GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity	2.077800e-3
GO:0072086	specification of loop of Henle identity	2.103215e-3
GO:0045988	negative regulation of striated muscle contraction	2.107711e-3
GO:0032231	regulation of actin filament bundle assembly	2.124865e-3
GO:0009074	aromatic amino acid family catabolic process	2.126111e-3
GO:0030828	positive regulation of cGMP biosynthetic process	2.140039e-3
GO:0043314	negative regulation of neutrophil degranulation	2.140039e-3
GO:0090303	positive regulation of wound healing	2.140102e-3
GO:0007369	gastrulation	2.148321e-3
GO:0051533	positive regulation of NFAT protein import into nucleus	2.157315e-3
GO:0060037	pharyngeal system development	2.175052e-3
GO:0014060	regulation of epinephrine secretion	2.185191e-3
GO:0031644	regulation of neurological system process	2.208650e-3
GO:0006014	D-ribose metabolic process	2.255703e-3
GO:0023061	signal release	2.275707e-3
GO:0008016	regulation of heart contraction	2.285458e-3
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	2.307788e-3
GO:0010529	negative regulation of transposition	2.352741e-3
GO:0048199	vesicle targeting, to, from or within Golgi	2.385477e-3
GO:0060291	long-term synaptic potentiation	2.385477e-3
GO:0044319	wound healing, spreading of cells	2.432437e-3
GO:0051014	actin filament severing	2.457304e-3
GO:0009443	pyridoxal 5'-phosphate salvage	2.488139e-3
GO:0072176	nephric duct development	2.495604e-3
GO:0060154	cellular process regulating host cell cycle in response to virus	2.498849e-3
GO:0035883	enteroendocrine cell differentiation	2.513114e-3
GO:0019439	aromatic compound catabolic process	2.518390e-3
GO:0007501	mesodermal cell fate specification	2.531524e-3
GO:0045833	negative regulation of lipid metabolic process	2.533294e-3
GO:0043583	ear development	2.541605e-3
GO:0043001	Golgi to plasma membrane protein transport	2.602054e-3
GO:0048242	epinephrine secretion	2.612665e-3
GO:2000466	negative regulation of glycogen (starch) synthase activity	2.614333e-3
GO:0035771	interleukin-4-mediated signaling pathway	2.614333e-3
GO:0060444	branching involved in mammary gland duct morphogenesis	2.636404e-3
GO:0051572	negative regulation of histone H3-K4 methylation	2.699549e-3
GO:0050819	negative regulation of coagulation	2.796421e-3
GO:0014912	negative regulation of smooth muscle cell migration	2.798608e-3
GO:0060555	induction of necroptosis by extracellular signals	2.805591e-3
GO:0001955	blood vessel maturation	2.836177e-3
GO:0032856	activation of Ras GTPase activity	2.871833e-3
GO:0021569	rhombomere 3 development	2.873862e-3
GO:0021599	abducens nerve formation	2.879292e-3
GO:0007634	optokinetic behavior	2.879292e-3
GO:0055015	ventricular cardiac muscle cell development	2.888527e-3
GO:0008217	regulation of blood pressure	2.892251e-3
GO:0030195	negative regulation of blood coagulation	2.958096e-3
GO:0072537	fibroblast activation	2.981073e-3
GO:0007136	meiotic prophase II	2.981073e-3
GO:0033505	floor plate morphogenesis	2.992728e-3
GO:0072178	nephric duct morphogenesis	2.999288e-3
GO:0072040	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis	2.999996e-3
GO:0010638	positive regulation of organelle organization	3.101792e-3
GO:0002384	hepatic immune response	3.172429e-3
GO:0016486	peptide hormone processing	3.183361e-3
GO:0003017	lymph circulation	3.187219e-3
GO:0032233	positive regulation of actin filament bundle assembly	3.249809e-3
GO:0046902	regulation of mitochondrial membrane permeability	3.328654e-3
GO:0009880	embryonic pattern specification	3.398742e-3
GO:0051928	positive regulation of calcium ion transport	3.413008e-3
GO:0031058	positive regulation of histone modification	3.459107e-3
GO:0009048	dosage compensation, by inactivation of X chromosome	3.480989e-3
GO:0006901	vesicle coating	3.491503e-3
GO:0035306	positive regulation of dephosphorylation	3.493892e-3
GO:0051208	sequestering of calcium ion	3.518270e-3
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	3.521127e-3
GO:0050850	positive regulation of calcium-mediated signaling	3.546315e-3
GO:0021603	cranial nerve formation	3.549339e-3
GO:0060259	regulation of feeding behavior	3.564079e-3
GO:0046889	positive regulation of lipid biosynthetic process	3.592580e-3
GO:0032753	positive regulation of interleukin-4 production	3.655733e-3
GO:0042593	glucose homeostasis	3.693683e-3
GO:0070141	response to UV-A	3.700424e-3
GO:2000016	negative regulation of determination of dorsal identity	3.705187e-3
GO:0060003	copper ion export	3.705187e-3
GO:0015677	copper ion import	3.705187e-3
GO:0030327	prenylated protein catabolic process	3.705187e-3
GO:0000271	polysaccharide biosynthetic process	3.720854e-3
GO:0019062	virion attachment to host cell surface receptor	3.727927e-3
GO:0071109	superior temporal gyrus development	3.769619e-3
GO:0065001	specification of axis polarity	3.783004e-3
GO:0051969	regulation of transmission of nerve impulse	3.808863e-3
GO:0019322	pentose biosynthetic process	3.837694e-3
GO:0006570	tyrosine metabolic process	3.885259e-3
GO:0006527	arginine catabolic process	3.893534e-3
GO:0021877	forebrain neuron fate commitment	3.894339e-3
GO:0048845	venous blood vessel morphogenesis	3.913301e-3
GO:0032204	regulation of telomere maintenance	3.937657e-3
GO:0007296	vitellogenesis	3.990416e-3
GO:0002439	chronic inflammatory response to antigenic stimulus	4.026099e-3
GO:0035356	cellular triglyceride homeostasis	4.188603e-3
GO:0072107	positive regulation of ureteric bud formation	4.190096e-3
GO:0018119	peptidyl-cysteine S-nitrosylation	4.212882e-3
GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	4.230485e-3
GO:0072385	minus-end-directed organelle transport along microtubule	4.286935e-3
GO:0043901	negative regulation of multi-organism process	4.310659e-3
GO:0010390	histone monoubiquitination	4.344774e-3
GO:0050995	negative regulation of lipid catabolic process	4.398234e-3
GO:0001505	regulation of neurotransmitter levels	4.435739e-3
GO:0051055	negative regulation of lipid biosynthetic process	4.442046e-3
GO:0044130	negative regulation of growth of symbiont in host	4.505438e-3
GO:0006559	L-phenylalanine catabolic process	4.541383e-3
GO:0006684	sphingomyelin metabolic process	4.684470e-3
GO:0071218	cellular response to misfolded protein	4.686626e-3
GO:0042472	inner ear morphogenesis	4.734935e-3
GO:0045616	regulation of keratinocyte differentiation	4.745530e-3
GO:0016574	histone ubiquitination	4.773701e-3
GO:0018125	peptidyl-cysteine methylation	4.783645e-3
GO:0005981	regulation of glycogen catabolic process	4.803727e-3
GO:2000209	regulation of anoikis	4.818378e-3
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	4.824100e-3
GO:0070102	interleukin-6-mediated signaling pathway	4.828808e-3
GO:0031062	positive regulation of histone methylation	4.836955e-3
GO:0043491	protein kinase B signaling cascade	4.896908e-3
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	4.952597e-3
GO:0040040	thermosensory behavior	4.984310e-3
GO:0031547	brain-derived neurotrophic factor receptor signaling pathway	5.021570e-3
GO:0006711	estrogen catabolic process	5.104796e-3
GO:0007269	neurotransmitter secretion	5.111922e-3
GO:0003184	pulmonary valve morphogenesis	5.159190e-3
GO:0019318	hexose metabolic process	5.172015e-3
GO:0007263	nitric oxide mediated signal transduction	5.206061e-3
GO:0003180	aortic valve morphogenesis	5.228791e-3
GO:0051970	negative regulation of transmission of nerve impulse	5.259048e-3
GO:0032855	positive regulation of Rac GTPase activity	5.270201e-3
GO:0010536	positive regulation of activation of Janus kinase activity	5.338399e-3
GO:0007498	mesoderm development	5.343263e-3
GO:0007435	salivary gland morphogenesis	5.379178e-3
GO:0042421	norepinephrine biosynthetic process	5.388536e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	5.499918e-3
GO:2000054	negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	5.523442e-3
GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	5.536562e-3
GO:0030540	female genitalia development	5.619101e-3
GO:0006825	copper ion transport	5.637412e-3
GO:0032464	positive regulation of protein homooligomerization	5.641059e-3
GO:0043128	positive regulation of 1-phosphatidylinositol 4-kinase activity	5.645082e-3
GO:0009436	glyoxylate catabolic process	5.688614e-3
GO:0022417	protein maturation by protein folding	5.871116e-3
GO:0023021	termination of signal transduction	5.939205e-3
GO:0021759	globus pallidus development	5.939205e-3
GO:0003108	negative regulation of the force of heart contraction by chemical signal	5.939205e-3
GO:0048562	embryonic organ morphogenesis	5.979665e-3
GO:0046684	response to pyrethroid	6.070948e-3
GO:0050832	defense response to fungus	6.074621e-3
GO:0060370	susceptibility to T cell mediated cytotoxicity	6.103805e-3
GO:0006493	protein O-linked glycosylation	6.134907e-3
GO:0051402	neuron apoptosis	6.152867e-3
GO:0035048	splicing factor protein import into nucleus	6.250484e-3
GO:0000415	negative regulation of histone H3-K36 methylation	6.323062e-3
GO:0072657	protein localization in membrane	6.471946e-3
GO:0046814	virion attachment, binding of host cell surface coreceptor	6.489380e-3
GO:0051898	negative regulation of protein kinase B signaling cascade	6.499462e-3
GO:0051241	negative regulation of multicellular organismal process	6.630143e-3
GO:0071354	cellular response to interleukin-6	6.634269e-3
GO:0010712	regulation of collagen metabolic process	6.650725e-3
GO:0060928	atrioventricular node cell development	6.707501e-3
GO:0090222	centrosome-templated microtubule nucleation	6.707501e-3
GO:0060929	atrioventricular node cell fate commitment	6.707501e-3
GO:0003342	proepicardium development	6.707501e-3
GO:0003168	cardiac Purkinje fiber cell differentiation	6.707501e-3
GO:0055014	atrial cardiac muscle cell development	6.712009e-3
GO:0042819	vitamin B6 biosynthetic process	6.712009e-3
GO:0030836	positive regulation of actin filament depolymerization	6.716311e-3
GO:0008078	mesodermal cell migration	6.739040e-3
GO:0008090	retrograde axon cargo transport	6.764067e-3
GO:0009635	response to herbicide	6.789465e-3
GO:0045940	positive regulation of steroid metabolic process	6.804188e-3
GO:0045932	negative regulation of muscle contraction	6.822544e-3
GO:0048208	COPII vesicle coating	6.831602e-3
GO:0060073	micturition	6.978948e-3
GO:0031295	T cell costimulation	7.067157e-3
GO:0043313	regulation of neutrophil degranulation	7.132684e-3
GO:0046426	negative regulation of JAK-STAT cascade	7.223255e-3
GO:0051580	regulation of neurotransmitter uptake	7.223255e-3
GO:0021702	cerebellar Purkinje cell differentiation	7.230515e-3
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	7.236467e-3
GO:0031167	rRNA methylation	7.236467e-3
GO:0010940	positive regulation of necrotic cell death	7.335835e-3
GO:0031060	regulation of histone methylation	7.347133e-3
GO:2000543	positive regulation of gastrulation	7.381730e-3
GO:0022027	interkinetic nuclear migration	7.381730e-3
GO:0007595	lactation	7.410811e-3
GO:0044070	regulation of anion transport	7.511586e-3
GO:0002537	nitric oxide production involved in inflammatory response	7.585336e-3
GO:0002740	negative regulation of cytokine secretion involved in immune response	7.598676e-3
GO:0051764	actin crosslink formation	7.640152e-3
GO:0072089	stem cell proliferation	7.676273e-3
GO:0033158	regulation of protein import into nucleus, translocation	7.681915e-3
GO:0019054	modulation by virus of host cellular process	7.695788e-3
GO:0003062	regulation of heart rate by chemical signal	7.767901e-3
GO:0070842	aggresome assembly	7.767901e-3
GO:0030834	regulation of actin filament depolymerization	7.801186e-3
GO:0035725	sodium ion transmembrane transport	7.868118e-3
GO:0042088	T-helper 1 type immune response	7.910473e-3
GO:0009072	aromatic amino acid family metabolic process	7.934720e-3
GO:0046548	retinal rod cell development	7.957675e-3
GO:0045916	negative regulation of complement activation	8.000966e-3
GO:0051953	negative regulation of amine transport	8.003300e-3
GO:0050805	negative regulation of synaptic transmission	8.072064e-3
GO:0045721	negative regulation of gluconeogenesis	8.146831e-3
GO:0010821	regulation of mitochondrion organization	8.218933e-3
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	8.267158e-3
GO:0060312	regulation of blood vessel remodeling	8.278468e-3
GO:0045575	basophil activation	8.278468e-3
GO:0001694	histamine biosynthetic process	8.278468e-3
GO:2000679	positive regulation of transcription regulatory region DNA binding	8.336685e-3
GO:0019064	viral envelope fusion with host membrane	8.399434e-3
GO:0071276	cellular response to cadmium ion	8.413613e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0007522	visceral muscle development	9.656975e-21
GO:0055009	atrial cardiac muscle tissue morphogenesis	1.629740e-19
GO:0030049	muscle filament sliding	1.645712e-17
GO:0070646	protein modification by small protein removal	1.635661e-16
GO:0016579	protein deubiquitination	4.403158e-15
GO:0048739	cardiac muscle fiber development	6.063761e-15
GO:0031133	regulation of axon diameter	2.130573e-10
GO:0030509	BMP signaling pathway	2.255928e-10
GO:0048598	embryonic morphogenesis	3.965541e-9
GO:0009952	anterior/posterior pattern specification	4.349740e-9
GO:0032536	regulation of cell projection size	8.009055e-9
GO:0055010	ventricular cardiac muscle tissue morphogenesis	9.180435e-9
GO:0003002	regionalization	1.218701e-8
GO:0003209	cardiac atrium morphogenesis	2.364144e-8
GO:0043462	regulation of ATPase activity	3.189725e-8
GO:0002026	regulation of the force of heart contraction	6.787243e-8
GO:0006970	response to osmotic stress	7.533826e-8
GO:0003229	ventricular cardiac muscle tissue development	8.657000e-8
GO:0014056	regulation of acetylcholine secretion	8.865517e-8
GO:0048568	embryonic organ development	1.361029e-7
GO:0006941	striated muscle contraction	1.748105e-7
GO:0001702	gastrulation with mouth forming second	1.945602e-7
GO:0033275	actin-myosin filament sliding	2.097520e-7
GO:0007369	gastrulation	2.272443e-7
GO:0003230	cardiac atrium development	2.525085e-7
GO:0009950	dorsal/ventral axis specification	2.765667e-7
GO:0007389	pattern specification process	3.699136e-7
GO:0071371	cellular response to gonadotropin stimulus	4.913558e-7
GO:0048705	skeletal system morphogenesis	6.388368e-7
GO:0009798	axis specification	8.401266e-7
GO:2000053	regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	9.143050e-7
GO:0048332	mesoderm morphogenesis	1.089129e-6
GO:0007281	germ cell development	1.689762e-6
GO:0070252	actin-mediated cell contraction	1.888552e-6
GO:0001707	mesoderm formation	1.896584e-6
GO:0016055	Wnt receptor signaling pathway	2.122736e-6
GO:0007213	muscarinic acetylcholine receptor signaling pathway	2.169979e-6
GO:0021707	cerebellar granule cell differentiation	2.277110e-6
GO:0021575	hindbrain morphogenesis	2.326935e-6
GO:0021871	forebrain regionalization	2.602920e-6
GO:0007398	ectoderm development	4.425361e-6
GO:0021797	forebrain anterior/posterior pattern specification	4.456967e-6
GO:0010595	positive regulation of endothelial cell migration	4.547903e-6
GO:0071456	cellular response to hypoxia	4.553305e-6
GO:0021532	neural tube patterning	6.389563e-6
GO:0006700	C21-steroid hormone biosynthetic process	6.858110e-6
GO:0021587	cerebellum morphogenesis	8.398815e-6
GO:0030382	sperm mitochondrion organization	8.723773e-6
GO:0071453	cellular response to oxygen levels	9.817867e-6
GO:0050883	musculoskeletal movement, spinal reflex action	1.183995e-5
GO:0051336	regulation of hydrolase activity	1.302092e-5
GO:0006366	transcription from RNA polymerase II promoter	1.336492e-5
GO:0007498	mesoderm development	1.480875e-5
GO:0022415	viral reproductive process	1.895848e-5
GO:0048747	muscle fiber development	2.100345e-5
GO:0032423	regulation of mismatch repair	2.320325e-5
GO:0022601	menstrual cycle phase	2.388720e-5
GO:2000465	regulation of glycogen (starch) synthase activity	2.478089e-5
GO:0009790	embryo development	2.495547e-5
GO:0009953	dorsal/ventral pattern formation	2.952867e-5
GO:0072539	T-helper 17 cell differentiation	3.043051e-5
GO:0000266	mitochondrial fission	3.053737e-5
GO:0021683	cerebellar granular layer morphogenesis	3.324225e-5
GO:0035855	megakaryocyte development	3.622414e-5
GO:0046628	positive regulation of insulin receptor signaling pathway	3.664601e-5
GO:0060056	mammary gland involution	3.772261e-5
GO:0034698	response to gonadotropin stimulus	3.787115e-5
GO:0033083	regulation of immature T cell proliferation	3.922309e-5
GO:0014012	peripheral nervous system axon regeneration	3.950180e-5
GO:0090009	primitive streak formation	4.073642e-5
GO:0046325	negative regulation of glucose import	4.283956e-5
GO:0045585	positive regulation of cytotoxic T cell differentiation	4.319270e-5
GO:0030644	cellular chloride ion homeostasis	4.409628e-5
GO:2000467	positive regulation of glycogen (starch) synthase activity	4.501421e-5
GO:0090273	regulation of somatostatin secretion	4.963808e-5
GO:0006836	neurotransmitter transport	4.983516e-5
GO:0021750	vestibular nucleus development	5.668739e-5
GO:0021590	cerebellum maturation	5.668739e-5
GO:0021679	cerebellar molecular layer development	5.668739e-5
GO:0033121	regulation of purine nucleotide catabolic process	5.761217e-5
GO:0048255	mRNA stabilization	6.053259e-5
GO:0072104	glomerular capillary formation	6.492879e-5
GO:0048240	sperm capacitation	6.630684e-5
GO:0003310	pancreatic A cell differentiation	6.967547e-5
GO:0048008	platelet-derived growth factor receptor signaling pathway	7.251410e-5
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	7.373451e-5
GO:0002052	positive regulation of neuroblast proliferation	7.880590e-5
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	8.071215e-5
GO:0032354	response to follicle-stimulating hormone stimulus	8.187669e-5
GO:0048562	embryonic organ morphogenesis	8.365448e-5
GO:0060070	canonical Wnt receptor signaling pathway	8.380597e-5
GO:0032908	regulation of transforming growth factor beta1 production	8.392321e-5
GO:0046709	IDP catabolic process	8.477375e-5
GO:0046032	ADP catabolic process	8.477375e-5
GO:0001709	cell fate determination	9.074998e-5
GO:0010829	negative regulation of glucose transport	1.054765e-4
GO:0016079	synaptic vesicle exocytosis	1.218583e-4
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	1.257122e-4
GO:0006704	glucocorticoid biosynthetic process	1.341621e-4
GO:0001704	formation of primary germ layer	1.363213e-4
GO:0030641	regulation of cellular pH	1.372187e-4
GO:0000052	citrulline metabolic process	1.531683e-4
GO:0014051	gamma-aminobutyric acid secretion	1.577676e-4
GO:0046031	ADP metabolic process	1.577676e-4
GO:0051956	negative regulation of amino acid transport	1.601515e-4
GO:0003006	developmental process involved in reproduction	1.627474e-4
GO:0016926	protein desumoylation	1.635792e-4
GO:0035659	Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells	1.645748e-4
GO:0014719	satellite cell activation	1.645748e-4
GO:0071545	inositol phosphate catabolic process	1.763711e-4
GO:0033084	regulation of immature T cell proliferation in thymus	1.763711e-4
GO:0007626	locomotory behavior	1.814073e-4
GO:0060415	muscle tissue morphogenesis	2.006781e-4
GO:0045750	positive regulation of S phase of mitotic cell cycle	2.017419e-4
GO:0046677	response to antibiotic	2.056332e-4
GO:2000054	negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	2.226565e-4
GO:0031102	neuron projection regeneration	2.226805e-4
GO:0006972	hyperosmotic response	2.239359e-4
GO:0009948	anterior/posterior axis specification	2.399703e-4
GO:0072102	glomerulus morphogenesis	2.413604e-4
GO:0007109	cytokinesis, completion of separation	2.527791e-4
GO:0031103	axon regeneration	2.553557e-4
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	2.621806e-4
GO:0045085	negative regulation of interleukin-2 biosynthetic process	2.623528e-4
GO:0060021	palate development	2.629027e-4
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	2.705772e-4
GO:0009653	anatomical structure morphogenesis	2.846271e-4
GO:0032922	circadian regulation of gene expression	2.914592e-4
GO:0003309	type B pancreatic cell differentiation	2.974648e-4
GO:0044087	regulation of cellular component biogenesis	3.025971e-4
GO:0030574	collagen catabolic process	3.046772e-4
GO:0030004	cellular monovalent inorganic cation homeostasis	3.367279e-4
GO:0007286	spermatid development	3.404373e-4
GO:0090244	Wnt receptor signaling pathway involved in somitogenesis	3.419895e-4
GO:0015812	gamma-aminobutyric acid transport	3.458402e-4
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.526960e-4
GO:0030326	embryonic limb morphogenesis	3.558782e-4
GO:0051893	regulation of focal adhesion assembly	3.614997e-4
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	3.638458e-4
GO:0042326	negative regulation of phosphorylation	3.708501e-4
GO:0007224	smoothened signaling pathway	3.781985e-4
GO:0055008	cardiac muscle tissue morphogenesis	3.860233e-4
GO:0006979	response to oxidative stress	3.966183e-4
GO:0002238	response to molecule of fungal origin	4.024394e-4
GO:0071372	cellular response to follicle-stimulating hormone stimulus	4.680271e-4
GO:0031329	regulation of cellular catabolic process	4.708888e-4
GO:0009635	response to herbicide	4.813119e-4
GO:0035094	response to nicotine	4.895759e-4
GO:0007269	neurotransmitter secretion	4.899069e-4
GO:0045109	intermediate filament organization	4.942358e-4
GO:0010799	regulation of peptidyl-threonine phosphorylation	5.070145e-4
GO:0008217	regulation of blood pressure	5.167745e-4
GO:0044332	Wnt receptor signaling pathway involved in dorsal/ventral axis specification	5.177734e-4
GO:0046092	deoxycytidine metabolic process	5.177734e-4
GO:0035990	tendon cell differentiation	5.177734e-4
GO:0010970	microtubule-based transport	5.181783e-4
GO:0042775	mitochondrial ATP synthesis coupled electron transport	5.182635e-4
GO:0006909	phagocytosis	5.211240e-4
GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	5.260667e-4
GO:0051604	protein maturation	5.275184e-4
GO:0030320	cellular monovalent inorganic anion homeostasis	5.613454e-4
GO:0060218	hemopoietic stem cell differentiation	5.613847e-4
GO:0001501	skeletal system development	5.613954e-4
GO:0021578	hindbrain maturation	5.718296e-4
GO:0060338	regulation of type I interferon-mediated signaling pathway	5.726295e-4
GO:0043279	response to alkaloid	5.797208e-4
GO:0009894	regulation of catabolic process	5.951952e-4
GO:0032911	negative regulation of transforming growth factor beta1 production	5.994313e-4
GO:0015804	neutral amino acid transport	6.038662e-4
GO:0009299	mRNA transcription	6.231191e-4
GO:0010717	regulation of epithelial to mesenchymal transition	6.270398e-4
GO:0015747	urate transport	6.591121e-4
GO:2000164	negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis	6.614933e-4
GO:2000162	negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	6.614933e-4
GO:2000166	negative regulation of planar cell polarity pathway involved in pericardium morphogenesis	6.614933e-4
GO:2000168	negative regulation of planar cell polarity pathway involved in neural tube closure	6.614933e-4
GO:0061310	canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development	6.614933e-4
GO:2000055	positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	6.614933e-4
GO:2000149	negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	6.614933e-4
GO:2000151	negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	6.614933e-4
GO:0000578	embryonic axis specification	6.725449e-4
GO:0061088	regulation of sequestering of zinc ion	6.796650e-4
GO:0030219	megakaryocyte differentiation	6.840557e-4
GO:0050917	sensory perception of umami taste	6.976698e-4
GO:0033091	positive regulation of immature T cell proliferation	7.108368e-4
GO:0032535	regulation of cellular component size	7.301978e-4
GO:0030099	myeloid cell differentiation	7.341241e-4
GO:0006119	oxidative phosphorylation	7.344535e-4
GO:0021533	cell differentiation in hindbrain	7.508856e-4
GO:0048268	clathrin coat assembly	7.552075e-4
GO:0060235	lens induction in camera-type eye	7.676915e-4
GO:0034655	nucleobase-containing compound catabolic process	7.757800e-4
GO:0043487	regulation of RNA stability	8.027988e-4
GO:0045576	mast cell activation	8.429775e-4
GO:0072215	regulation of metanephros development	8.434609e-4
GO:0010898	positive regulation of triglyceride catabolic process	8.622557e-4
GO:0032674	regulation of interleukin-5 production	8.913903e-4
GO:0001938	positive regulation of endothelial cell proliferation	9.305897e-4
GO:0021696	cerebellar cortex morphogenesis	9.331005e-4
GO:0017145	stem cell division	9.363973e-4
GO:0072125	negative regulation of glomerular mesangial cell proliferation	9.400231e-4
GO:0071634	regulation of transforming growth factor beta production	9.446036e-4
GO:0060231	mesenchymal to epithelial transition	9.477801e-4
GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	9.588229e-4
GO:0003231	cardiac ventricle development	9.823948e-4
GO:0051955	regulation of amino acid transport	1.009146e-3
GO:0050881	musculoskeletal movement	1.016646e-3
GO:0019682	glyceraldehyde-3-phosphate metabolic process	1.060727e-3
GO:0021978	telencephalon regionalization	1.061850e-3
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	1.062883e-3
GO:0048678	response to axon injury	1.064817e-3
GO:0072124	regulation of glomerular mesangial cell proliferation	1.076052e-3
GO:0018963	phthalate metabolic process	1.076052e-3
GO:0008344	adult locomotory behavior	1.090105e-3
GO:0009261	ribonucleotide catabolic process	1.093795e-3
GO:0030501	positive regulation of bone mineralization	1.111586e-3
GO:0000302	response to reactive oxygen species	1.131457e-3
GO:2000117	negative regulation of cysteine-type endopeptidase activity	1.131865e-3
GO:0032425	positive regulation of mismatch repair	1.131865e-3
GO:0009150	purine ribonucleotide metabolic process	1.143873e-3
GO:0006901	vesicle coating	1.149966e-3
GO:0003009	skeletal muscle contraction	1.177502e-3
GO:0070169	positive regulation of biomineral tissue development	1.200640e-3
GO:0061038	uterus morphogenesis	1.206509e-3
GO:0042789	mRNA transcription from RNA polymerase II promoter	1.212199e-3
GO:0002077	acrosome matrix dispersal	1.212199e-3
GO:0051952	regulation of amine transport	1.225012e-3
GO:0009620	response to fungus	1.226592e-3
GO:0051896	regulation of protein kinase B signaling cascade	1.235675e-3
GO:0071397	cellular response to cholesterol	1.243517e-3
GO:0072012	glomerulus vasculature development	1.253329e-3
GO:0050792	regulation of viral reproduction	1.255382e-3
GO:0034101	erythrocyte homeostasis	1.257475e-3
GO:0042773	ATP synthesis coupled electron transport	1.260173e-3
GO:0043488	regulation of mRNA stability	1.279754e-3
GO:0021904	dorsal/ventral neural tube patterning	1.280292e-3
GO:0009651	response to salt stress	1.305435e-3
GO:0070647	protein modification by small protein conjugation or removal	1.334933e-3
GO:0009154	purine ribonucleotide catabolic process	1.371002e-3
GO:0016082	synaptic vesicle priming	1.386313e-3
GO:0009166	nucleotide catabolic process	1.420764e-3
GO:0032989	cellular component morphogenesis	1.425579e-3
GO:0060444	branching involved in mammary gland duct morphogenesis	1.425591e-3
GO:0015802	basic amino acid transport	1.461026e-3
GO:0045936	negative regulation of phosphate metabolic process	1.462159e-3
GO:0048266	behavioral response to pain	1.464479e-3
GO:0060242	contact inhibition	1.475822e-3
GO:0044270	cellular nitrogen compound catabolic process	1.477024e-3
GO:0030220	platelet formation	1.514086e-3
GO:0048639	positive regulation of developmental growth	1.533736e-3
GO:0051412	response to corticosterone stimulus	1.575831e-3
GO:0032849	positive regulation of cellular pH reduction	1.578916e-3
GO:0007512	adult heart development	1.579809e-3
GO:0072198	mesenchymal cell proliferation involved in ureter development	1.595506e-3
GO:0072192	ureter epithelial cell differentiation	1.595506e-3
GO:0072138	mesenchymal cell proliferation involved in ureteric bud development	1.595506e-3
GO:0072101	specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway	1.595506e-3
GO:2000137	negative regulation of cell proliferation involved in heart morphogenesis	1.595506e-3
GO:2000007	negative regulation of metanephric comma-shaped body morphogenesis	1.595506e-3
GO:2000005	negative regulation of metanephric S-shaped body morphogenesis	1.595506e-3
GO:0090194	negative regulation of glomerulus development	1.595506e-3
GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis	1.595506e-3
GO:0072200	negative regulation of mesenchymal cell proliferation involved in ureter development	1.595506e-3
GO:0060502	epithelial cell proliferation involved in lung morphogenesis	1.595506e-3
GO:0072097	negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway	1.595506e-3
GO:0048392	intermediate mesodermal cell differentiation	1.595506e-3
GO:0007500	mesodermal cell fate determination	1.595506e-3
GO:0060503	bud dilation involved in lung branching	1.595506e-3
GO:0055020	positive regulation of cardiac muscle fiber development	1.595506e-3
GO:0071893	BMP signaling pathway involved in nephric duct formation	1.595506e-3
GO:0061155	pulmonary artery endothelial tube morphogenesis	1.595506e-3
GO:0061151	BMP signaling pathway involved in renal system segmentation	1.595506e-3
GO:0061149	BMP signaling pathway involved in ureter morphogenesis	1.595506e-3
GO:0035166	post-embryonic hemopoiesis	1.612984e-3
GO:0009205	purine ribonucleoside triphosphate metabolic process	1.620877e-3
GO:0048644	muscle organ morphogenesis	1.631982e-3
GO:0046855	inositol phosphate dephosphorylation	1.633110e-3
GO:0032506	cytokinetic process	1.697126e-3
GO:0070309	lens fiber cell morphogenesis	1.719315e-3
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	1.729132e-3
GO:0009199	ribonucleoside triphosphate metabolic process	1.735081e-3
GO:0048549	positive regulation of pinocytosis	1.823289e-3
GO:0061005	cell differentiation involved in kidney development	1.841396e-3
GO:0032909	regulation of transforming growth factor beta2 production	1.843628e-3
GO:0072262	metanephric glomerular mesangial cell proliferation involved in metanephros development	1.854667e-3
GO:0010810	regulation of cell-substrate adhesion	1.869411e-3
GO:0060024	rhythmic synaptic transmission	1.897720e-3
GO:0001933	negative regulation of protein phosphorylation	1.941620e-3
GO:0016485	protein processing	1.950679e-3
GO:0072112	glomerular visceral epithelial cell differentiation	1.983705e-3
GO:0006195	purine nucleotide catabolic process	2.032651e-3
GO:0002062	chondrocyte differentiation	2.054537e-3
GO:0007029	endoplasmic reticulum organization	2.059527e-3
GO:0072203	cell proliferation involved in metanephros development	2.110544e-3
GO:0048333	mesodermal cell differentiation	2.200282e-3
GO:0035524	proline transmembrane transport	2.202829e-3
GO:0021985	neurohypophysis development	2.211550e-3
GO:0000238	zygotene	2.211550e-3
GO:0007023	post-chaperonin tubulin folding pathway	2.211550e-3
GO:0006436	tryptophanyl-tRNA aminoacylation	2.255279e-3
GO:0046856	phosphatidylinositol dephosphorylation	2.333322e-3
GO:0016032	viral reproduction	2.354528e-3
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	2.378303e-3
GO:0019060	intracellular transport of viral proteins in host cell	2.406260e-3
GO:0046967	cytosol to ER transport	2.406260e-3
GO:0014057	positive regulation of acetylcholine secretion	2.406260e-3
GO:0010045	response to nickel ion	2.406260e-3
GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions	2.406260e-3
GO:0044243	multicellular organismal catabolic process	2.436544e-3
GO:0048548	regulation of pinocytosis	2.495961e-3
GO:0032780	negative regulation of ATPase activity	2.495961e-3
GO:0046839	phospholipid dephosphorylation	2.514416e-3
GO:0060059	embryonic retina morphogenesis in camera-type eye	2.526825e-3
GO:0043503	skeletal muscle fiber adaptation	2.553533e-3
GO:0042744	hydrogen peroxide catabolic process	2.555070e-3
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	2.568181e-3
GO:0050996	positive regulation of lipid catabolic process	2.576059e-3
GO:0032352	positive regulation of hormone metabolic process	2.620559e-3
GO:0032350	regulation of hormone metabolic process	2.652351e-3
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	2.703587e-3
GO:0032811	negative regulation of epinephrine secretion	2.723914e-3
GO:0048265	response to pain	2.727270e-3
GO:0032754	positive regulation of interleukin-5 production	2.745814e-3
GO:0019058	viral infectious cycle	2.760650e-3
GO:0009887	organ morphogenesis	2.768490e-3
GO:0090245	axis elongation involved in somitogenesis	2.774954e-3
GO:0021874	Wnt receptor signaling pathway involved in forebrain neuroblast division	2.774954e-3
GO:0016925	protein sumoylation	2.801958e-3
GO:0010629	negative regulation of gene expression	2.817203e-3
GO:0051385	response to mineralocorticoid stimulus	2.833857e-3
GO:0051216	cartilage development	2.842052e-3
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	2.914696e-3
GO:0090169	regulation of spindle assembly	2.914696e-3
GO:0090234	regulation of kinetochore assembly	2.914696e-3
GO:0035444	nickel ion transmembrane transport	2.914696e-3
GO:0032148	activation of protein kinase B activity	2.922684e-3
GO:0021681	cerebellar granular layer development	2.922684e-3
GO:0032677	regulation of interleukin-8 production	2.931959e-3
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.943595e-3
GO:0032967	positive regulation of collagen biosynthetic process	2.959062e-3
GO:0046543	development of secondary female sexual characteristics	3.001507e-3
GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	3.011477e-3
GO:2000242	negative regulation of reproductive process	3.011844e-3
GO:0009826	unidimensional cell growth	3.026819e-3
GO:0048610	cellular process involved in reproduction	3.027245e-3
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	3.029965e-3
GO:0006477	protein sulfation	3.043758e-3
GO:0043584	nose development	3.127175e-3
GO:0046034	ATP metabolic process	3.134741e-3
GO:2000683	regulation of cellular response to X-ray	3.285719e-3
GO:0003205	cardiac chamber development	3.311567e-3
GO:0051875	pigment granule localization	3.388995e-3
GO:0003208	cardiac ventricle morphogenesis	3.405904e-3
GO:2000611	positive regulation of thyroid hormone generation	3.412121e-3
GO:0033092	positive regulation of immature T cell proliferation in thymus	3.412121e-3
GO:0018879	biphenyl metabolic process	3.441908e-3
GO:0051453	regulation of intracellular pH	3.460078e-3
GO:0090342	regulation of cell aging	3.469332e-3
GO:0032412	regulation of ion transmembrane transporter activity	3.504702e-3
GO:0002027	regulation of heart rate	3.517654e-3
GO:0072384	organelle transport along microtubule	3.536121e-3
GO:0032689	negative regulation of interferon-gamma production	3.555401e-3
GO:0072668	tubulin complex biogenesis	3.585895e-3
GO:0009141	nucleoside triphosphate metabolic process	3.646290e-3
GO:0060279	positive regulation of ovulation	3.667546e-3
GO:0006868	glutamine transport	3.710811e-3
GO:0071480	cellular response to gamma radiation	3.710811e-3
GO:0072111	cell proliferation involved in kidney development	3.715845e-3
GO:0072523	purine-containing compound catabolic process	3.756330e-3
GO:0035850	epithelial cell differentiation involved in kidney development	3.778161e-3
GO:0043303	mast cell degranulation	3.809080e-3
GO:0003344	pericardium morphogenesis	3.814613e-3
GO:0015684	ferrous iron transport	3.831937e-3
GO:0031115	negative regulation of microtubule polymerization	3.867248e-3
GO:0048293	regulation of isotype switching to IgE isotypes	3.868983e-3
GO:0046700	heterocycle catabolic process	3.980750e-3
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.987679e-3
GO:0060981	cell migration involved in coronary angiogenesis	4.014298e-3
GO:0071670	smooth muscle cell chemotaxis	4.014298e-3
GO:2000016	negative regulation of determination of dorsal identity	4.014298e-3
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	4.014298e-3
GO:0050916	sensory perception of sweet taste	4.014298e-3
GO:0022417	protein maturation by protein folding	4.014298e-3
GO:0006710	androgen catabolic process	4.014298e-3
GO:0023035	CD40 signaling pathway	4.014298e-3
GO:0021903	rostrocaudal neural tube patterning	4.116741e-3
GO:0043299	leukocyte degranulation	4.122110e-3
GO:0046637	regulation of alpha-beta T cell differentiation	4.194247e-3
GO:0010628	positive regulation of gene expression	4.223795e-3
GO:0009144	purine nucleoside triphosphate metabolic process	4.232106e-3
GO:0072098	anterior/posterior pattern specification involved in kidney development	4.243271e-3
GO:0002036	regulation of L-glutamate transport	4.243271e-3
GO:0048389	intermediate mesoderm development	4.243271e-3
GO:0014909	smooth muscle cell migration	4.243271e-3
GO:0043653	mitochondrial fragmentation involved in apoptosis	4.243271e-3
GO:0030513	positive regulation of BMP signaling pathway	4.310800e-3
GO:0051492	regulation of stress fiber assembly	4.316516e-3
GO:0090068	positive regulation of cell cycle process	4.332667e-3
GO:0034442	regulation of lipoprotein oxidation	4.374910e-3
GO:0010466	negative regulation of peptidase activity	4.443063e-3
GO:0071108	protein K48-linked deubiquitination	4.488416e-3
GO:0060686	negative regulation of prostatic bud formation	4.488416e-3
GO:0048103	somatic stem cell division	4.497712e-3
GO:0060689	cell differentiation involved in salivary gland development	4.507045e-3
GO:0032400	melanosome localization	4.526659e-3
GO:0023061	signal release	4.536143e-3
GO:0072015	glomerular visceral epithelial cell development	4.553791e-3
GO:0009259	ribonucleotide metabolic process	4.571068e-3
GO:0017156	calcium ion-dependent exocytosis	4.582904e-3
GO:0043932	ossification involved in bone remodeling	4.621052e-3
GO:0009235	cobalamin metabolic process	4.621052e-3
GO:0015862	uridine transport	4.621052e-3
GO:0019048	virus-host interaction	4.621811e-3
GO:0045893	positive regulation of transcription, DNA-dependent	4.689531e-3
GO:0044140	negative regulation of growth of symbiont on or near host surface	4.702392e-3
GO:0070086	ubiquitin-dependent endocytosis	4.702392e-3
GO:0042703	menstruation	4.702392e-3
GO:0006780	uroporphyrinogen III biosynthetic process	4.702392e-3
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	4.702392e-3
GO:0018293	protein-FAD linkage	4.702392e-3
GO:0019101	female somatic sex determination	4.702392e-3
GO:0016486	peptide hormone processing	4.760393e-3
GO:0032736	positive regulation of interleukin-13 production	4.781460e-3
GO:0035518	histone H2A monoubiquitination	4.788797e-3
GO:0021979	hypothalamus cell differentiation	4.791786e-3
GO:0018931	naphthalene metabolic process	4.791786e-3
GO:0001675	acrosome assembly	4.810256e-3
GO:0030048	actin filament-based movement	4.815916e-3
GO:0042733	embryonic digit morphogenesis	4.889895e-3
GO:0031113	regulation of microtubule polymerization	4.907271e-3
GO:0030970	retrograde protein transport, ER to cytosol	4.909228e-3
GO:0061156	pulmonary artery morphogenesis	4.960362e-3
GO:0051851	modification by host of symbiont morphology or physiology	4.975327e-3
GO:0045066	regulatory T cell differentiation	4.985883e-3
GO:0001657	ureteric bud development	5.007575e-3
GO:0046849	bone remodeling	5.019813e-3
GO:0051897	positive regulation of protein kinase B signaling cascade	5.020476e-3
GO:2000664	positive regulation of interleukin-5 secretion	5.144892e-3
GO:2000667	positive regulation of interleukin-13 secretion	5.144892e-3
GO:2000703	negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	5.144892e-3
GO:2000734	negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	5.144892e-3
GO:2000607	negative regulation of cell proliferation involved in mesonephros development	5.144892e-3
GO:0001806	type IV hypersensitivity	5.144892e-3
GO:0060014	granulosa cell differentiation	5.144892e-3
GO:0060374	mast cell differentiation	5.144892e-3
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	5.161120e-3
GO:0060430	lung saccule development	5.188730e-3
GO:0021794	thalamus development	5.202393e-3
GO:0035162	embryonic hemopoiesis	5.237584e-3
GO:0045069	regulation of viral genome replication	5.243195e-3
GO:0002524	hypersensitivity	5.293359e-3
GO:0007018	microtubule-based movement	5.314526e-3
GO:0009207	purine ribonucleoside triphosphate catabolic process	5.355257e-3
GO:0035249	synaptic transmission, glutamatergic	5.357169e-3
GO:0051253	negative regulation of RNA metabolic process	5.360842e-3
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	5.364825e-3
GO:0042538	hyperosmotic salinity response	5.364825e-3
GO:0050748	negative regulation of lipoprotein metabolic process	5.373965e-3
GO:0023019	signal transduction involved in regulation of gene expression	5.441205e-3
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	5.444707e-3
GO:0008361	regulation of cell size	5.444707e-3
GO:0048704	embryonic skeletal system morphogenesis	5.525980e-3
GO:0060390	regulation of SMAD protein import into nucleus	5.619940e-3
GO:0071407	cellular response to organic cyclic compound	5.676536e-3
GO:0006635	fatty acid beta-oxidation	5.715805e-3
GO:0071276	cellular response to cadmium ion	5.753456e-3
GO:0043647	inositol phosphate metabolic process	5.775620e-3
GO:0051271	negative regulation of cellular component movement	5.781867e-3
GO:0021549	cerebellum development	5.827911e-3
GO:0060676	ureteric bud formation	5.867448e-3
GO:0048729	tissue morphogenesis	5.871289e-3
GO:0032271	regulation of protein polymerization	5.911145e-3
GO:0045892	negative regulation of transcription, DNA-dependent	5.956709e-3
GO:0021861	forebrain radial glial cell differentiation	6.053397e-3
GO:0070271	protein complex biogenesis	6.064909e-3
GO:0060760	positive regulation of response to cytokine stimulus	6.065222e-3
GO:2000194	regulation of female gonad development	6.118789e-3
GO:0042474	middle ear morphogenesis	6.154323e-3
GO:0001578	microtubule bundle formation	6.198896e-3
GO:0061046	regulation of branching involved in lung morphogenesis	6.246684e-3
GO:0002438	acute inflammatory response to antigenic stimulus	6.265602e-3
GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing	6.293433e-3
GO:0043401	steroid hormone mediated signaling pathway	6.329221e-3
GO:0045814	negative regulation of gene expression, epigenetic	6.363709e-3
GO:0030218	erythrocyte differentiation	6.389134e-3
GO:0090183	regulation of kidney development	6.394614e-3
GO:0033327	Leydig cell differentiation	6.494220e-3
GO:0070193	synaptonemal complex organization	6.505700e-3
GO:0033132	negative regulation of glucokinase activity	6.552719e-3
GO:0061181	regulation of chondrocyte development	6.552719e-3
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	6.552719e-3
GO:0031658	negative regulation of cyclin-dependent protein kinase activity involved in G1/S	6.552719e-3
GO:0007092	activation of mitotic anaphase-promoting complex activity	6.552719e-3
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	6.574590e-3
GO:0000904	cell morphogenesis involved in differentiation	6.624225e-3
GO:0021796	cerebral cortex regionalization	6.656027e-3
GO:0010594	regulation of endothelial cell migration	6.725611e-3
GO:0045995	regulation of embryonic development	6.745985e-3
GO:0061004	pattern specification involved in kidney development	6.899996e-3
GO:0006513	protein monoubiquitination	6.900905e-3