Novel motif:41

name:	motif41_TSACAA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0050896	response to stimulus	4.375161e-73
GO:0042221	response to chemical stimulus	8.501461e-55
GO:0050789	regulation of biological process	7.856232e-50
GO:0023052	signaling	3.401041e-48
GO:0007165	signal transduction	4.042029e-48
GO:0065007	biological regulation	5.239501e-48
GO:0007154	cell communication	4.681751e-47
GO:0032501	multicellular organismal process	2.788571e-46
GO:0050794	regulation of cellular process	3.624950e-45
GO:0010038	response to metal ion	9.284913e-45
GO:0051716	cellular response to stimulus	3.391237e-44
GO:0051179	localization	3.416670e-42
GO:0006950	response to stress	1.810081e-40
GO:0009611	response to wounding	1.234640e-39
GO:0051234	establishment of localization	8.010189e-39
GO:0032502	developmental process	7.014543e-38
GO:0006810	transport	1.020016e-37
GO:0051592	response to calcium ion	3.731325e-36
GO:0042060	wound healing	4.169713e-36
GO:0010035	response to inorganic substance	6.616049e-36
GO:0002376	immune system process	9.617037e-36
GO:0001775	cell activation	1.464354e-33
GO:0007166	cell surface receptor linked signaling pathway	3.176843e-31
GO:0007275	multicellular organismal development	1.922725e-30
GO:0002684	positive regulation of immune system process	1.394239e-29
GO:0048856	anatomical structure development	4.194444e-29
GO:0002576	platelet degranulation	1.899332e-28
GO:0065008	regulation of biological quality	1.239461e-27
GO:0048769	sarcomerogenesis	6.434532e-27
GO:0030168	platelet activation	4.416387e-26
GO:0048583	regulation of response to stimulus	6.785394e-26
GO:0048513	organ development	1.529645e-25
GO:0009987	cellular process	2.853739e-25
GO:0007076	mitotic chromosome condensation	3.594566e-25
GO:0050790	regulation of catalytic activity	4.001802e-25
GO:0006928	cellular component movement	1.899269e-24
GO:0009888	tissue development	3.498757e-24
GO:0002682	regulation of immune system process	5.366854e-24
GO:0019220	regulation of phosphate metabolic process	9.807820e-24
GO:0007596	blood coagulation	2.811689e-23
GO:0055003	cardiac myofibril assembly	3.773613e-23
GO:0010033	response to organic substance	7.021146e-23
GO:0003008	system process	7.526906e-23
GO:0007599	hemostasis	8.243500e-23
GO:0002694	regulation of leukocyte activation	1.188423e-22
GO:0016192	vesicle-mediated transport	1.917627e-22
GO:0032879	regulation of localization	2.158866e-22
GO:0051338	regulation of transferase activity	2.776788e-22
GO:0042325	regulation of phosphorylation	3.064471e-22
GO:0050878	regulation of body fluid levels	1.758829e-21
GO:0030240	skeletal muscle thin filament assembly	2.822342e-21
GO:0000070	mitotic sister chromatid segregation	3.524259e-21
GO:0000819	sister chromatid segregation	5.451836e-21
GO:0048731	system development	5.805450e-21
GO:0050865	regulation of cell activation	6.062225e-21
GO:0046903	secretion	8.188092e-21
GO:0006911	phagocytosis, engulfment	9.797741e-21
GO:0044238	primary metabolic process	1.051592e-20
GO:0030261	chromosome condensation	1.741004e-20
GO:0019222	regulation of metabolic process	1.803880e-20
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	2.409181e-20
GO:0030241	skeletal muscle myosin thick filament assembly	4.257041e-20
GO:0001932	regulation of protein phosphorylation	5.500969e-20
GO:0043549	regulation of kinase activity	5.895156e-20
GO:0008152	metabolic process	6.664054e-20
GO:0006955	immune response	1.228741e-19
GO:0006952	defense response	1.306212e-19
GO:0032026	response to magnesium ion	1.993994e-19
GO:0031399	regulation of protein modification process	2.716983e-19
GO:0048519	negative regulation of biological process	7.253311e-19
GO:0048518	positive regulation of biological process	7.899567e-19
GO:0055013	cardiac muscle cell development	8.146591e-19
GO:0007517	muscle organ development	8.409068e-19
GO:0048644	muscle organ morphogenesis	1.435497e-18
GO:0031323	regulation of cellular metabolic process	1.768407e-18
GO:0043032	positive regulation of macrophage activation	2.919863e-18
GO:0051049	regulation of transport	4.563873e-18
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	5.804056e-18
GO:0006629	lipid metabolic process	1.079910e-17
GO:0048522	positive regulation of cellular process	1.527660e-17
GO:0018149	peptide cross-linking	1.648339e-17
GO:0071840	cellular component organization or biogenesis	1.730134e-17
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	2.243411e-17
GO:0048584	positive regulation of response to stimulus	3.188290e-17
GO:0065009	regulation of molecular function	3.235052e-17
GO:0002690	positive regulation of leukocyte chemotaxis	3.477022e-17
GO:0002696	positive regulation of leukocyte activation	4.261663e-17
GO:0048869	cellular developmental process	5.968783e-17
GO:0050867	positive regulation of cell activation	8.969089e-17
GO:2000191	regulation of fatty acid transport	9.487011e-17
GO:0080090	regulation of primary metabolic process	9.512273e-17
GO:0060415	muscle tissue morphogenesis	1.056045e-16
GO:0002687	positive regulation of leukocyte migration	1.205039e-16
GO:0014706	striated muscle tissue development	1.235143e-16
GO:0019538	protein metabolic process	1.286070e-16
GO:0010466	negative regulation of peptidase activity	1.310711e-16
GO:0016043	cellular component organization	1.435745e-16
GO:0032101	regulation of response to external stimulus	1.736797e-16
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport	1.740246e-16
GO:0045859	regulation of protein kinase activity	1.847283e-16
GO:0032940	secretion by cell	1.878544e-16
GO:0048468	cell development	1.981435e-16
GO:0043652	engulfment of apoptotic cell	2.266778e-16
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	2.266778e-16
GO:0010754	negative regulation of cGMP-mediated signaling	2.266778e-16
GO:0010751	negative regulation of nitric oxide mediated signal transduction	2.266778e-16
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	2.266778e-16
GO:0045765	regulation of angiogenesis	2.506433e-16
GO:0050795	regulation of behavior	3.500897e-16
GO:0002688	regulation of leukocyte chemotaxis	3.585529e-16
GO:0051893	regulation of focal adhesion assembly	3.983832e-16
GO:0055008	cardiac muscle tissue morphogenesis	4.030139e-16
GO:0009607	response to biotic stimulus	4.489532e-16
GO:0006897	endocytosis	6.388997e-16
GO:0002683	negative regulation of immune system process	7.174098e-16
GO:0045214	sarcomere organization	7.195035e-16
GO:0006954	inflammatory response	8.168545e-16
GO:0050776	regulation of immune response	9.803888e-16
GO:0032268	regulation of cellular protein metabolic process	1.048267e-15
GO:0071634	regulation of transforming growth factor beta production	1.129243e-15
GO:0009617	response to bacterium	1.205882e-15
GO:0050920	regulation of chemotaxis	1.238677e-15
GO:0072358	cardiovascular system development	1.496350e-15
GO:0009893	positive regulation of metabolic process	1.670971e-15
GO:0060537	muscle tissue development	1.677103e-15
GO:0048739	cardiac muscle fiber development	1.743297e-15
GO:0055007	cardiac muscle cell differentiation	1.806448e-15
GO:0048585	negative regulation of response to stimulus	1.992051e-15
GO:0014866	skeletal myofibril assembly	2.127193e-15
GO:0023051	regulation of signaling	2.298140e-15
GO:0030154	cell differentiation	2.419512e-15
GO:0051249	regulation of lymphocyte activation	2.823043e-15
GO:0060255	regulation of macromolecule metabolic process	3.485607e-15
GO:0050793	regulation of developmental process	3.573271e-15
GO:0009966	regulation of signal transduction	3.970690e-15
GO:0051707	response to other organism	4.326682e-15
GO:0009628	response to abiotic stimulus	5.340815e-15
GO:0009653	anatomical structure morphogenesis	6.278657e-15
GO:0051336	regulation of hydrolase activity	6.690386e-15
GO:0008202	steroid metabolic process	6.816577e-15
GO:0002685	regulation of leukocyte migration	1.020737e-14
GO:0046459	short-chain fatty acid metabolic process	1.036062e-14
GO:0006869	lipid transport	1.326080e-14
GO:0043086	negative regulation of catalytic activity	1.425789e-14
GO:0006887	exocytosis	1.718131e-14
GO:0002237	response to molecule of bacterial origin	2.167409e-14
GO:0010876	lipid localization	2.304984e-14
GO:0043030	regulation of macrophage activation	2.536931e-14
GO:0044237	cellular metabolic process	2.660420e-14
GO:0048523	negative regulation of cellular process	2.738192e-14
GO:0070887	cellular response to chemical stimulus	3.316145e-14
GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	3.582155e-14
GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	3.582155e-14
GO:0051895	negative regulation of focal adhesion assembly	3.708599e-14
GO:0015722	canalicular bile acid transport	3.765665e-14
GO:0006909	phagocytosis	3.793864e-14
GO:0006811	ion transport	4.039130e-14
GO:0016477	cell migration	4.105971e-14
GO:0042180	cellular ketone metabolic process	4.257613e-14
GO:0019752	carboxylic acid metabolic process	4.314203e-14
GO:0048520	positive regulation of behavior	4.385783e-14
GO:0040011	locomotion	4.560805e-14
GO:0048870	cell motility	4.924016e-14
GO:0052547	regulation of peptidase activity	5.390325e-14
GO:0046638	positive regulation of alpha-beta T cell differentiation	5.800241e-14
GO:0002253	activation of immune response	6.988120e-14
GO:0051704	multi-organism process	7.158656e-14
GO:0032496	response to lipopolysaccharide	8.409644e-14
GO:0048747	muscle fiber development	9.073123e-14
GO:0043170	macromolecule metabolic process	9.371536e-14
GO:0032914	positive regulation of transforming growth factor beta1 production	9.938663e-14
GO:0006464	protein modification process	1.056209e-13
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	1.290010e-13
GO:0032908	regulation of transforming growth factor beta1 production	1.381811e-13
GO:2000026	regulation of multicellular organismal development	1.473795e-13
GO:0050864	regulation of B cell activation	1.534644e-13
GO:0009968	negative regulation of signal transduction	1.575293e-13
GO:0050869	negative regulation of B cell activation	1.808722e-13
GO:0050778	positive regulation of immune response	1.850475e-13
GO:0050877	neurological system process	1.899456e-13
GO:0051641	cellular localization	2.101751e-13
GO:0022402	cell cycle process	2.134748e-13
GO:0023057	negative regulation of signaling	2.398865e-13
GO:0015718	monocarboxylic acid transport	2.759851e-13
GO:0055002	striated muscle cell development	2.923055e-13
GO:0010648	negative regulation of cell communication	3.448763e-13
GO:0006082	organic acid metabolic process	3.633846e-13
GO:0051246	regulation of protein metabolic process	3.648610e-13
GO:0052548	regulation of endopeptidase activity	5.260532e-13
GO:0003006	developmental process involved in reproduction	5.627618e-13
GO:0046635	positive regulation of alpha-beta T cell activation	7.638672e-13
GO:0061041	regulation of wound healing	7.693139e-13
GO:0035051	cardiac cell differentiation	8.853686e-13
GO:0000188	inactivation of MAPK activity	9.597723e-13
GO:0032695	negative regulation of interleukin-12 production	1.324179e-12
GO:0050921	positive regulation of chemotaxis	1.470346e-12
GO:0002544	chronic inflammatory response	1.547071e-12
GO:0003007	heart morphogenesis	1.639094e-12
GO:0043438	acetoacetic acid metabolic process	1.852888e-12
GO:0032989	cellular component morphogenesis	1.896955e-12
GO:0007049	cell cycle	2.107377e-12
GO:0010759	positive regulation of macrophage chemotaxis	2.198805e-12
GO:0050678	regulation of epithelial cell proliferation	2.286227e-12
GO:0032787	monocarboxylic acid metabolic process	2.395041e-12
GO:0015721	bile acid and bile salt transport	2.501867e-12
GO:0007507	heart development	2.683572e-12
GO:0055001	muscle cell development	3.024598e-12
GO:0061061	muscle structure development	3.162899e-12
GO:0034638	phosphatidylcholine catabolic process	3.468948e-12
GO:0002520	immune system development	3.611648e-12
GO:0048660	regulation of smooth muscle cell proliferation	3.636713e-12
GO:0043409	negative regulation of MAPKKK cascade	4.268588e-12
GO:0010604	positive regulation of macromolecule metabolic process	4.309994e-12
GO:0070536	protein K63-linked deubiquitination	5.927683e-12
GO:0042493	response to drug	5.971613e-12
GO:0034139	regulation of toll-like receptor 3 signaling pathway	6.280412e-12
GO:0048738	cardiac muscle tissue development	7.224404e-12
GO:0071622	regulation of granulocyte chemotaxis	7.262495e-12
GO:0045321	leukocyte activation	7.546838e-12
GO:0006796	phosphate-containing compound metabolic process	8.005952e-12
GO:0010758	regulation of macrophage chemotaxis	8.240226e-12
GO:2000345	regulation of hepatocyte proliferation	8.405409e-12
GO:0006941	striated muscle contraction	8.700172e-12
GO:0006323	DNA packaging	8.932864e-12
GO:0046634	regulation of alpha-beta T cell activation	9.408917e-12
GO:0002764	immune response-regulating signaling pathway	1.028680e-11
GO:0090291	negative regulation of osteoclast proliferation	1.235827e-11
GO:2000349	negative regulation of CD40 signaling pathway	1.235827e-11
GO:2000347	positive regulation of hepatocyte proliferation	1.235827e-11
GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.235827e-11
GO:0034148	negative regulation of toll-like receptor 5 signaling pathway	1.235827e-11
GO:0070429	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.235827e-11
GO:0072573	tolerance induction to lipopolysaccharide	1.235827e-11
GO:0051649	establishment of localization in cell	1.242572e-11
GO:0010757	negative regulation of plasminogen activation	1.299605e-11
GO:0043412	macromolecule modification	1.354623e-11
GO:0009894	regulation of catabolic process	1.603204e-11
GO:0045621	positive regulation of lymphocyte differentiation	1.623401e-11
GO:0002757	immune response-activating signal transduction	1.625344e-11
GO:0045740	positive regulation of DNA replication	1.676491e-11
GO:0048608	reproductive structure development	1.857433e-11
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	1.875934e-11
GO:0044092	negative regulation of molecular function	1.983499e-11
GO:0030335	positive regulation of cell migration	2.183393e-11
GO:0010646	regulation of cell communication	2.336689e-11
GO:0040007	growth	2.575118e-11
GO:0051346	negative regulation of hydrolase activity	2.601848e-11
GO:0034135	regulation of toll-like receptor 2 signaling pathway	2.691573e-11
GO:0048646	anatomical structure formation involved in morphogenesis	2.877516e-11
GO:0044267	cellular protein metabolic process	2.903490e-11
GO:0007059	chromosome segregation	3.061943e-11
GO:0080134	regulation of response to stress	3.066020e-11
GO:0032890	regulation of organic acid transport	4.362099e-11
GO:0032103	positive regulation of response to external stimulus	4.973172e-11
GO:0046637	regulation of alpha-beta T cell differentiation	5.274549e-11
GO:0031325	positive regulation of cellular metabolic process	6.002851e-11
GO:0071675	regulation of mononuclear cell migration	6.068091e-11
GO:0044255	cellular lipid metabolic process	6.541367e-11
GO:0048729	tissue morphogenesis	6.560787e-11
GO:0043154	negative regulation of caspase activity	6.729439e-11
GO:0072507	divalent inorganic cation homeostasis	6.769615e-11
GO:0030239	myofibril assembly	6.799716e-11
GO:0010763	positive regulation of fibroblast migration	6.968623e-11
GO:0030595	leukocyte chemotaxis	7.120050e-11
GO:0010595	positive regulation of endothelial cell migration	7.431510e-11
GO:0051348	negative regulation of transferase activity	7.830585e-11
GO:2000147	positive regulation of cell motility	8.999778e-11
GO:0019605	butyrate metabolic process	1.010531e-10
GO:0010755	regulation of plasminogen activation	1.094462e-10
GO:0010955	negative regulation of protein processing	1.131271e-10
GO:0045088	regulation of innate immune response	1.162209e-10
GO:0031032	actomyosin structure organization	1.393831e-10
GO:0046689	response to mercury ion	1.522392e-10
GO:0001936	regulation of endothelial cell proliferation	1.585794e-10
GO:0007186	G-protein coupled receptor protein signaling pathway	1.614055e-10
GO:0045766	positive regulation of angiogenesis	1.707863e-10
GO:0009056	catabolic process	1.732855e-10
GO:0043085	positive regulation of catalytic activity	1.909601e-10
GO:0071103	DNA conformation change	2.002068e-10
GO:0045137	development of primary sexual characteristics	2.033416e-10
GO:0031349	positive regulation of defense response	2.042505e-10
GO:0007040	lysosome organization	2.319443e-10
GO:0032891	negative regulation of organic acid transport	2.523854e-10
GO:0042692	muscle cell differentiation	2.635463e-10
GO:0060068	vagina development	2.709311e-10
GO:0051251	positive regulation of lymphocyte activation	2.885149e-10
GO:0051146	striated muscle cell differentiation	2.997440e-10
GO:0033144	negative regulation of steroid hormone receptor signaling pathway	2.999362e-10
GO:0044281	small molecule metabolic process	3.162105e-10
GO:0071636	positive regulation of transforming growth factor beta production	3.270362e-10
GO:0048511	rhythmic process	4.031848e-10
GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	4.417133e-10
GO:0001525	angiogenesis	4.519448e-10
GO:0046851	negative regulation of bone remodeling	4.652763e-10
GO:0043623	cellular protein complex assembly	4.762055e-10
GO:0030334	regulation of cell migration	4.835577e-10
GO:0043067	regulation of programmed cell death	5.159559e-10
GO:0000085	G2 phase of mitotic cell cycle	5.168437e-10
GO:0009605	response to external stimulus	5.170015e-10
GO:0055074	calcium ion homeostasis	6.027683e-10
GO:0009725	response to hormone stimulus	6.264947e-10
GO:0045779	negative regulation of bone resorption	6.306308e-10
GO:0048853	forebrain morphogenesis	7.073838e-10
GO:0006875	cellular metal ion homeostasis	7.167678e-10
GO:0035335	peptidyl-tyrosine dephosphorylation	7.420211e-10
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	7.556698e-10
GO:0010941	regulation of cell death	7.713259e-10
GO:0051094	positive regulation of developmental process	8.051089e-10
GO:0034373	intermediate-density lipoprotein particle remodeling	8.108580e-10
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	8.301206e-10
GO:0010741	negative regulation of intracellular protein kinase cascade	8.342137e-10
GO:0006874	cellular calcium ion homeostasis	9.202544e-10
GO:0050679	positive regulation of epithelial cell proliferation	9.423696e-10
GO:0040017	positive regulation of locomotion	1.124937e-9
GO:0048534	hemopoietic or lymphoid organ development	1.128904e-9
GO:0072503	cellular divalent inorganic cation homeostasis	1.170940e-9
GO:0044260	cellular macromolecule metabolic process	1.206324e-9
GO:0045582	positive regulation of T cell differentiation	1.257627e-9
GO:0050701	interleukin-1 secretion	1.289540e-9
GO:0007155	cell adhesion	1.412952e-9
GO:0032494	response to peptidoglycan	1.539119e-9
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	1.568251e-9
GO:0007548	sex differentiation	1.676888e-9
GO:0051171	regulation of nitrogen compound metabolic process	1.706285e-9
GO:0046660	female sex differentiation	1.727345e-9
GO:0048732	gland development	1.770978e-9
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	2.177956e-9
GO:0055065	metal ion homeostasis	2.326626e-9
GO:0042592	homeostatic process	2.416573e-9
GO:0048609	multicellular organismal reproductive process	2.452066e-9
GO:0033673	negative regulation of kinase activity	2.456446e-9
GO:0034762	regulation of transmembrane transport	2.512284e-9
GO:0045428	regulation of nitric oxide biosynthetic process	2.513924e-9
GO:2000116	regulation of cysteine-type endopeptidase activity	2.545924e-9
GO:0042981	regulation of apoptosis	2.577578e-9
GO:0042327	positive regulation of phosphorylation	2.619581e-9
GO:0035556	intracellular signal transduction	2.699668e-9
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	2.867892e-9
GO:2000352	negative regulation of endothelial cell apoptosis	3.070683e-9
GO:0030097	hemopoiesis	3.293655e-9
GO:0045089	positive regulation of innate immune response	3.311744e-9
GO:0042632	cholesterol homeostasis	3.559669e-9
GO:0019433	triglyceride catabolic process	3.859312e-9
GO:0007267	cell-cell signaling	3.981097e-9
GO:0033036	macromolecule localization	3.983233e-9
GO:0006275	regulation of DNA replication	4.123413e-9
GO:0048566	embryonic digestive tract development	4.155811e-9
GO:0002053	positive regulation of mesenchymal cell proliferation	4.261485e-9
GO:0045937	positive regulation of phosphate metabolic process	4.339127e-9
GO:0022602	ovulation cycle process	4.373596e-9
GO:0019219	regulation of nucleobase-containing compound metabolic process	4.381645e-9
GO:0051050	positive regulation of transport	4.449178e-9
GO:0009891	positive regulation of biosynthetic process	4.466737e-9
GO:0001922	B-1 B cell homeostasis	4.485975e-9
GO:0042698	ovulation cycle	4.569126e-9
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	4.638755e-9
GO:0060429	epithelium development	4.690250e-9
GO:0045627	positive regulation of T-helper 1 cell differentiation	4.716196e-9
GO:0007204	elevation of cytosolic calcium ion concentration	4.805170e-9
GO:0019725	cellular homeostasis	4.812115e-9
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	5.000240e-9
GO:0030155	regulation of cell adhesion	5.150321e-9
GO:0006468	protein phosphorylation	5.196465e-9
GO:0051272	positive regulation of cellular component movement	5.367255e-9
GO:0055088	lipid homeostasis	5.369936e-9
GO:0060548	negative regulation of cell death	6.085859e-9
GO:0032612	interleukin-1 production	6.107437e-9
GO:0043536	positive regulation of blood vessel endothelial cell migration	6.245204e-9
GO:0045429	positive regulation of nitric oxide biosynthetic process	6.649602e-9
GO:0034605	cellular response to heat	6.683306e-9
GO:0045624	positive regulation of T-helper cell differentiation	6.876268e-9
GO:0001816	cytokine production	7.036331e-9
GO:2000348	regulation of CD40 signaling pathway	7.214553e-9
GO:0016044	cellular membrane organization	7.993913e-9
GO:0040012	regulation of locomotion	8.025499e-9
GO:0048661	positive regulation of smooth muscle cell proliferation	8.123463e-9
GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation	8.911765e-9
GO:0051345	positive regulation of hydrolase activity	9.331560e-9
GO:2000351	regulation of endothelial cell apoptosis	9.365772e-9
GO:0045087	innate immune response	9.798215e-9
GO:0070301	cellular response to hydrogen peroxide	1.004158e-8
GO:0046649	lymphocyte activation	1.009297e-8
GO:0032663	regulation of interleukin-2 production	1.034405e-8
GO:0044248	cellular catabolic process	1.044214e-8
GO:0010557	positive regulation of macromolecule biosynthetic process	1.092815e-8
GO:0034143	regulation of toll-like receptor 4 signaling pathway	1.113774e-8
GO:0007276	gamete generation	1.191857e-8
GO:0061024	membrane organization	1.212035e-8
GO:0051917	regulation of fibrinolysis	1.235854e-8
GO:2000145	regulation of cell motility	1.375752e-8
GO:0006812	cation transport	1.405142e-8
GO:0070663	regulation of leukocyte proliferation	1.529464e-8
GO:0050870	positive regulation of T cell activation	1.546523e-8
GO:0055114	oxidation-reduction process	1.618958e-8
GO:0002604	regulation of dendritic cell antigen processing and presentation	1.790349e-8
GO:0030193	regulation of blood coagulation	1.810612e-8
GO:0006109	regulation of carbohydrate metabolic process	1.819961e-8
GO:0055080	cation homeostasis	1.891409e-8
GO:0046475	glycerophospholipid catabolic process	1.912818e-8
GO:0032317	regulation of Rap GTPase activity	1.928372e-8
GO:0002218	activation of innate immune response	1.942170e-8
GO:0051250	negative regulation of lymphocyte activation	1.997563e-8
GO:0043069	negative regulation of programmed cell death	2.036195e-8
GO:0043537	negative regulation of blood vessel endothelial cell migration	2.117801e-8
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	2.167907e-8
GO:0010464	regulation of mesenchymal cell proliferation	2.204340e-8
GO:0006916	anti-apoptosis	2.474203e-8
GO:0060749	mammary gland alveolus development	2.547026e-8
GO:0007417	central nervous system development	2.646400e-8
GO:0006470	protein dephosphorylation	2.723590e-8
GO:0001952	regulation of cell-matrix adhesion	2.726991e-8
GO:0051054	positive regulation of DNA metabolic process	2.762238e-8
GO:0050900	leukocyte migration	2.826098e-8
GO:0050931	pigment cell differentiation	2.855728e-8
GO:0043405	regulation of MAP kinase activity	3.281264e-8
GO:0009719	response to endogenous stimulus	3.342030e-8
GO:0008406	gonad development	3.395087e-8
GO:0032844	regulation of homeostatic process	3.515895e-8
GO:0007033	vacuole organization	3.557311e-8
GO:0016125	sterol metabolic process	3.575915e-8
GO:0022612	gland morphogenesis	3.831801e-8
GO:0060538	skeletal muscle organ development	3.895303e-8
GO:0019226	transmission of nerve impulse	3.986939e-8
GO:0050818	regulation of coagulation	4.118534e-8
GO:0008219	cell death	4.241916e-8
GO:0051248	negative regulation of protein metabolic process	4.339298e-8
GO:0007519	skeletal muscle tissue development	4.359334e-8
GO:0010675	regulation of cellular carbohydrate metabolic process	4.377102e-8
GO:0002832	negative regulation of response to biotic stimulus	4.666113e-8
GO:0022603	regulation of anatomical structure morphogenesis	4.892524e-8
GO:0030850	prostate gland development	5.061678e-8
GO:0046716	muscle cell homeostasis	5.189938e-8
GO:0071842	cellular component organization at cellular level	5.199635e-8
GO:0001655	urogenital system development	5.250602e-8
GO:0030049	muscle filament sliding	5.330058e-8
GO:0032652	regulation of interleukin-1 production	5.500681e-8
GO:0016311	dephosphorylation	5.786422e-8
GO:0010269	response to selenium ion	6.407772e-8
GO:0050663	cytokine secretion	6.446220e-8
GO:0002577	regulation of antigen processing and presentation	6.643942e-8
GO:0070252	actin-mediated cell contraction	6.682728e-8
GO:0042953	lipoprotein transport	6.718793e-8
GO:0051918	negative regulation of fibrinolysis	6.758639e-8
GO:0034104	negative regulation of tissue remodeling	6.810226e-8
GO:0051570	regulation of histone H3-K9 methylation	6.818045e-8
GO:0030888	regulation of B cell proliferation	6.895377e-8
GO:0006816	calcium ion transport	7.082557e-8
GO:2000379	positive regulation of reactive oxygen species metabolic process	7.094874e-8
GO:0050702	interleukin-1 beta secretion	7.279235e-8
GO:0035162	embryonic hemopoiesis	7.509229e-8
GO:0007229	integrin-mediated signaling pathway	7.860473e-8
GO:0008037	cell recognition	7.905685e-8
GO:0006807	nitrogen compound metabolic process	8.002420e-8
GO:0003012	muscle system process	8.038373e-8
GO:0032854	positive regulation of Rap GTPase activity	8.259803e-8
GO:0016265	death	8.426809e-8
GO:0006935	chemotaxis	8.443116e-8
GO:0010828	positive regulation of glucose transport	8.468164e-8
GO:0031329	regulation of cellular catabolic process	8.622492e-8
GO:0034763	negative regulation of transmembrane transport	8.661948e-8
GO:0001780	neutrophil homeostasis	8.663629e-8
GO:0051574	positive regulation of histone H3-K9 methylation	9.233926e-8
GO:0031328	positive regulation of cellular biosynthetic process	9.782339e-8
GO:0043066	negative regulation of apoptosis	9.946074e-8
GO:0007268	synaptic transmission	1.093022e-7
GO:0032703	negative regulation of interleukin-2 production	1.105915e-7
GO:0071841	cellular component organization or biogenesis at cellular level	1.111586e-7
GO:0046503	glycerolipid catabolic process	1.135488e-7
GO:0002695	negative regulation of leukocyte activation	1.152097e-7
GO:0032495	response to muramyl dipeptide	1.161595e-7
GO:0070101	positive regulation of chemokine-mediated signaling pathway	1.182237e-7
GO:0014048	regulation of glutamate secretion	1.189538e-7
GO:0051480	cytosolic calcium ion homeostasis	1.267094e-7
GO:0007528	neuromuscular junction development	1.271312e-7
GO:0046545	development of primary female sexual characteristics	1.326000e-7
GO:0001667	ameboidal cell migration	1.347343e-7
GO:0071901	negative regulation of protein serine/threonine kinase activity	1.378587e-7
GO:0006469	negative regulation of protein kinase activity	1.400055e-7
GO:0030003	cellular cation homeostasis	1.557592e-7
GO:0032651	regulation of interleukin-1 beta production	1.648096e-7
GO:0030522	intracellular receptor mediated signaling pathway	1.657266e-7
GO:0008585	female gonad development	1.662564e-7
GO:0021509	roof plate formation	1.774888e-7
GO:0070613	regulation of protein processing	1.782934e-7
GO:0010885	regulation of cholesterol storage	1.818780e-7
GO:0046464	acylglycerol catabolic process	1.831221e-7
GO:0012501	programmed cell death	1.846784e-7
GO:0071900	regulation of protein serine/threonine kinase activity	1.930695e-7
GO:0030318	melanocyte differentiation	1.993725e-7
GO:0043535	regulation of blood vessel endothelial cell migration	2.033660e-7
GO:0001961	positive regulation of cytokine-mediated signaling pathway	2.111750e-7
GO:0050708	regulation of protein secretion	2.120285e-7
GO:0044036	cell wall macromolecule metabolic process	2.137779e-7
GO:0010927	cellular component assembly involved in morphogenesis	2.167197e-7
GO:0006508	proteolysis	2.198393e-7
GO:0051052	regulation of DNA metabolic process	2.246991e-7
GO:0042127	regulation of cell proliferation	2.249860e-7
GO:0051128	regulation of cellular component organization	2.285544e-7
GO:0006083	acetate metabolic process	2.296568e-7
GO:0071827	plasma lipoprotein particle organization	2.407694e-7

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0050896	response to stimulus	2.300564e-17
GO:0009605	response to external stimulus	1.953597e-16
GO:0006581	acetylcholine catabolic process	2.245051e-15
GO:0030488	tRNA methylation	4.597108e-13
GO:0051716	cellular response to stimulus	7.434029e-13
GO:0008291	acetylcholine metabolic process	1.920591e-12
GO:0031667	response to nutrient levels	4.940935e-12
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway	1.155163e-11
GO:0007584	response to nutrient	2.209935e-11
GO:0023052	signaling	3.750566e-10
GO:0007154	cell communication	3.985226e-10
GO:0007165	signal transduction	4.856079e-10
GO:0009991	response to extracellular stimulus	5.602595e-10
GO:0006952	defense response	9.998274e-10
GO:0051704	multi-organism process	1.089912e-9
GO:0019695	choline metabolic process	1.126289e-9
GO:0002455	humoral immune response mediated by circulating immunoglobulin	1.238113e-9
GO:0045213	neurotransmitter receptor metabolic process	1.378120e-9
GO:0002076	osteoblast development	1.651510e-9
GO:0035588	G-protein coupled purinergic receptor signaling pathway	2.016629e-9
GO:0019730	antimicrobial humoral response	2.408791e-9
GO:0065008	regulation of biological quality	3.021411e-9
GO:0006950	response to stress	4.266422e-9
GO:0007033	vacuole organization	7.129979e-9
GO:0035590	purinergic nucleotide receptor signaling pathway	7.189507e-9
GO:0009310	amine catabolic process	1.046271e-8
GO:0042221	response to chemical stimulus	1.053127e-8
GO:0030183	B cell differentiation	1.688288e-8
GO:0045212	neurotransmitter receptor biosynthetic process	1.831897e-8
GO:0007600	sensory perception	1.840018e-8
GO:0007166	cell surface receptor linked signaling pathway	1.892855e-8
GO:0045187	regulation of circadian sleep/wake cycle, sleep	2.358598e-8
GO:0051707	response to other organism	2.410042e-8
GO:0009628	response to abiotic stimulus	2.598750e-8
GO:0007040	lysosome organization	2.921560e-8
GO:0009617	response to bacterium	3.316325e-8
GO:0002684	positive regulation of immune system process	3.637777e-8
GO:0019731	antibacterial humoral response	4.900982e-8
GO:0009607	response to biotic stimulus	5.272429e-8
GO:0042832	defense response to protozoan	5.585404e-8
GO:0050865	regulation of cell activation	7.310773e-8
GO:0019836	hemolysis by symbiont of host erythrocytes	7.893686e-8
GO:0032501	multicellular organismal process	8.119562e-8
GO:0002313	mature B cell differentiation involved in immune response	8.682195e-8
GO:0002252	immune effector process	9.397855e-8
GO:0001562	response to protozoan	9.579793e-8
GO:0002694	regulation of leukocyte activation	1.025342e-7
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	1.225922e-7
GO:0042438	melanin biosynthetic process	1.349916e-7
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	1.388349e-7
GO:0007156	homophilic cell adhesion	1.790317e-7
GO:0035587	purinergic receptor signaling pathway	1.880392e-7
GO:0007286	spermatid development	2.026701e-7
GO:0045621	positive regulation of lymphocyte differentiation	2.057242e-7
GO:0007599	hemostasis	2.345216e-7
GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	2.987105e-7
GO:0022410	circadian sleep/wake cycle process	2.997961e-7
GO:0002682	regulation of immune system process	3.180165e-7
GO:0002521	leukocyte differentiation	3.321611e-7
GO:0042745	circadian sleep/wake cycle	3.402168e-7
GO:0007596	blood coagulation	3.507708e-7
GO:0048513	organ development	3.602616e-7
GO:0070541	response to platinum ion	4.144269e-7
GO:0002696	positive regulation of leukocyte activation	4.530376e-7
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	4.644291e-7
GO:0009612	response to mechanical stimulus	5.158084e-7
GO:0060117	auditory receptor cell development	5.546260e-7
GO:0000105	histidine biosynthetic process	5.842807e-7
GO:0002312	B cell activation involved in immune response	5.945128e-7
GO:0007608	sensory perception of smell	6.008543e-7
GO:0050906	detection of stimulus involved in sensory perception	6.445092e-7
GO:0030098	lymphocyte differentiation	7.045268e-7
GO:0042135	neurotransmitter catabolic process	7.230848e-7
GO:0006790	sulfur compound metabolic process	7.546512e-7
GO:0044003	modification by symbiont of host morphology or physiology	8.101352e-7
GO:0070227	lymphocyte apoptosis	1.021732e-6
GO:0060041	retina development in camera-type eye	1.175072e-6
GO:0009063	cellular amino acid catabolic process	1.187588e-6
GO:0050878	regulation of body fluid levels	1.205127e-6
GO:0001654	eye development	1.250288e-6
GO:0031623	receptor internalization	1.269654e-6
GO:0002702	positive regulation of production of molecular mediator of immune response	1.314803e-6
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	1.325593e-6
GO:0048240	sperm capacitation	1.398315e-6
GO:0009611	response to wounding	1.411510e-6
GO:0021537	telencephalon development	1.424164e-6
GO:0043056	forward locomotion	1.427947e-6
GO:0003333	amino acid transmembrane transport	1.441984e-6
GO:0042440	pigment metabolic process	1.558771e-6
GO:0006898	receptor-mediated endocytosis	1.609259e-6
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	1.658618e-6
GO:0050867	positive regulation of cell activation	1.668061e-6
GO:0048512	circadian behavior	1.863981e-6
GO:0045321	leukocyte activation	1.881245e-6
GO:0002700	regulation of production of molecular mediator of immune response	1.911847e-6
GO:0006436	tryptophanyl-tRNA aminoacylation	1.925234e-6
GO:0002683	negative regulation of immune system process	2.015835e-6
GO:0048583	regulation of response to stimulus	2.162652e-6
GO:0045494	photoreceptor cell maintenance	2.306060e-6
GO:0006582	melanin metabolic process	2.316609e-6
GO:0002335	mature B cell differentiation	2.333015e-6
GO:0002376	immune system process	2.616556e-6
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	2.649414e-6
GO:0050776	regulation of immune response	2.972231e-6
GO:0021987	cerebral cortex development	3.096035e-6
GO:0045214	sarcomere organization	3.275132e-6
GO:0006955	immune response	3.393806e-6
GO:0006954	inflammatory response	3.468039e-6
GO:0000103	sulfate assimilation	3.760319e-6
GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation	4.615752e-6
GO:0016064	immunoglobulin mediated immune response	5.232301e-6
GO:0042753	positive regulation of circadian rhythm	5.369251e-6
GO:0032438	melanosome organization	5.614832e-6
GO:0002237	response to molecule of bacterial origin	5.677553e-6
GO:0046649	lymphocyte activation	5.713945e-6
GO:0051249	regulation of lymphocyte activation	5.879433e-6
GO:0042759	long-chain fatty acid biosynthetic process	6.107855e-6
GO:0009083	branched chain family amino acid catabolic process	6.189903e-6
GO:0060401	cytosolic calcium ion transport	6.258298e-6
GO:0007411	axon guidance	6.796248e-6
GO:0010507	negative regulation of autophagy	6.829593e-6
GO:0007186	G-protein coupled receptor protein signaling pathway	6.838431e-6
GO:0009396	folic acid-containing compound biosynthetic process	7.105976e-6
GO:0050974	detection of mechanical stimulus involved in sensory perception	7.172534e-6
GO:0045671	negative regulation of osteoclast differentiation	7.200764e-6
GO:0065007	biological regulation	7.220485e-6
GO:0019724	B cell mediated immunity	7.221857e-6
GO:0045582	positive regulation of T cell differentiation	7.311739e-6
GO:0002093	auditory receptor cell morphogenesis	7.597527e-6
GO:0002285	lymphocyte activation involved in immune response	7.775269e-6
GO:0014706	striated muscle tissue development	8.525829e-6
GO:0052547	regulation of peptidase activity	8.720926e-6
GO:0033280	response to vitamin D	8.746336e-6
GO:0051883	killing of cells in other organism involved in symbiotic interaction	9.741977e-6
GO:0032496	response to lipopolysaccharide	9.943303e-6
GO:0060402	calcium ion transport into cytosol	1.041273e-5
GO:0050789	regulation of biological process	1.072000e-5
GO:0040011	locomotion	1.107125e-5
GO:0048738	cardiac muscle tissue development	1.160428e-5
GO:0010466	negative regulation of peptidase activity	1.161447e-5
GO:0070207	protein homotrimerization	1.202341e-5
GO:0048034	heme O biosynthetic process	1.212476e-5
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.293944e-5
GO:0045444	fat cell differentiation	1.298559e-5
GO:0031640	killing of cells of other organism	1.299999e-5
GO:0060537	muscle tissue development	1.339808e-5
GO:0042110	T cell activation	1.346997e-5
GO:0042594	response to starvation	1.372599e-5
GO:0048515	spermatid differentiation	1.378989e-5
GO:0006970	response to osmotic stress	1.518345e-5
GO:0048667	cell morphogenesis involved in neuron differentiation	1.568282e-5
GO:0002449	lymphocyte mediated immunity	1.612385e-5
GO:0048856	anatomical structure development	1.650055e-5
GO:0007026	negative regulation of microtubule depolymerization	1.760743e-5
GO:0050982	detection of mechanical stimulus	1.766671e-5
GO:0045926	negative regulation of growth	1.846597e-5
GO:0050670	regulation of lymphocyte proliferation	1.867104e-5
GO:0032332	positive regulation of chondrocyte differentiation	1.989296e-5
GO:0002443	leukocyte mediated immunity	2.030792e-5
GO:0031114	regulation of microtubule depolymerization	2.068292e-5
GO:0070663	regulation of leukocyte proliferation	2.136903e-5
GO:0032944	regulation of mononuclear cell proliferation	2.175008e-5
GO:0045348	positive regulation of MHC class II biosynthetic process	2.181760e-5
GO:0048869	cellular developmental process	2.193008e-5
GO:0006278	RNA-dependent DNA replication	2.246956e-5
GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein	2.263322e-5
GO:0033058	directional locomotion	2.275983e-5
GO:0042752	regulation of circadian rhythm	2.452297e-5
GO:0006916	anti-apoptosis	2.524434e-5
GO:0050870	positive regulation of T cell activation	2.531111e-5
GO:0030154	cell differentiation	2.546232e-5
GO:0051606	detection of stimulus	2.650965e-5
GO:0043010	camera-type eye development	2.669747e-5
GO:0055002	striated muscle cell development	2.763250e-5
GO:0050808	synapse organization	2.770012e-5
GO:0042060	wound healing	2.939885e-5
GO:0001783	B cell apoptosis	3.055695e-5
GO:0048013	ephrin receptor signaling pathway	3.056059e-5
GO:0003006	developmental process involved in reproduction	3.067009e-5
GO:0007409	axonogenesis	3.092766e-5
GO:0022602	ovulation cycle process	3.106588e-5
GO:0048305	immunoglobulin secretion	3.213683e-5
GO:0001775	cell activation	3.259389e-5
GO:0001503	ossification	3.361201e-5
GO:0006400	tRNA modification	3.479953e-5
GO:0055001	muscle cell development	3.480542e-5
GO:0002329	pre-B cell differentiation	3.486227e-5
GO:0022610	biological adhesion	3.496855e-5
GO:0020028	hemoglobin import	3.626057e-5
GO:0048852	diencephalon morphogenesis	3.695404e-5
GO:0007512	adult heart development	3.730732e-5
GO:0032502	developmental process	3.737987e-5
GO:0051251	positive regulation of lymphocyte activation	3.744008e-5
GO:0032094	response to food	3.874039e-5
GO:0048609	multicellular organismal reproductive process	4.053024e-5
GO:0019748	secondary metabolic process	4.075701e-5
GO:0032800	receptor biosynthetic process	4.135480e-5
GO:0007622	rhythmic behavior	4.171140e-5
GO:0050863	regulation of T cell activation	4.288941e-5
GO:0060088	auditory receptor cell stereocilium organization	4.396833e-5
GO:0051239	regulation of multicellular organismal process	4.539056e-5
GO:2000026	regulation of multicellular organismal development	4.560866e-5
GO:0030239	myofibril assembly	4.696617e-5
GO:0043900	regulation of multi-organism process	4.710741e-5
GO:0042113	B cell activation	4.840306e-5
GO:0090199	regulation of release of cytochrome c from mitochondria	4.840552e-5
GO:0071985	multivesicular body sorting pathway	4.862638e-5
GO:0006520	cellular amino acid metabolic process	4.900920e-5
GO:0051961	negative regulation of nervous system development	5.036654e-5
GO:0048753	pigment granule organization	5.304878e-5
GO:0071496	cellular response to external stimulus	5.352095e-5
GO:0006935	chemotaxis	5.681455e-5
GO:0050777	negative regulation of immune response	6.001112e-5
GO:0045668	negative regulation of osteoblast differentiation	6.093632e-5
GO:0042402	cellular biogenic amine catabolic process	6.643859e-5
GO:0010033	response to organic substance	6.665894e-5
GO:0055013	cardiac muscle cell development	6.757602e-5
GO:0030502	negative regulation of bone mineralization	6.784067e-5
GO:0070168	negative regulation of biomineral tissue development	6.823137e-5
GO:0006082	organic acid metabolic process	7.180200e-5
GO:0050953	sensory perception of light stimulus	7.290414e-5
GO:0050794	regulation of cellular process	7.350270e-5
GO:0060632	regulation of microtubule-based movement	7.473782e-5
GO:0042180	cellular ketone metabolic process	7.707861e-5
GO:0031032	actomyosin structure organization	7.911338e-5
GO:0006865	amino acid transport	7.954361e-5
GO:0046013	regulation of T cell homeostatic proliferation	7.989977e-5
GO:0009582	detection of abiotic stimulus	8.092809e-5
GO:0042330	taxis	8.098733e-5
GO:0019374	galactolipid metabolic process	8.154843e-5
GO:0043480	pigment accumulation in tissues	8.172306e-5
GO:0015837	amine transport	8.357947e-5
GO:0006928	cellular component movement	8.378061e-5
GO:0046689	response to mercury ion	8.694155e-5
GO:0035058	nonmotile primary cilium assembly	8.834669e-5
GO:0007494	midgut development	9.042724e-5
GO:0007601	visual perception	9.189329e-5
GO:0002315	marginal zone B cell differentiation	9.374038e-5
GO:0022603	regulation of anatomical structure morphogenesis	9.543202e-5
GO:0050850	positive regulation of calcium-mediated signaling	9.552900e-5
GO:0042522	regulation of tyrosine phosphorylation of Stat5 protein	9.610834e-5
GO:0016192	vesicle-mediated transport	9.612297e-5
GO:0019752	carboxylic acid metabolic process	9.827019e-5
GO:0032989	cellular component morphogenesis	9.888765e-5
GO:0046148	pigment biosynthetic process	9.962684e-5
GO:0045137	development of primary sexual characteristics	9.967754e-5
GO:0019376	galactolipid catabolic process	1.036320e-4
GO:0008283	cell proliferation	1.065126e-4
GO:0009081	branched chain family amino acid metabolic process	1.074635e-4
GO:0042403	thyroid hormone metabolic process	1.099929e-4
GO:0007155	cell adhesion	1.100034e-4
GO:0048854	brain morphogenesis	1.113819e-4
GO:0048534	hemopoietic or lymphoid organ development	1.144581e-4
GO:0006787	porphyrin-containing compound catabolic process	1.169032e-4
GO:0030308	negative regulation of cell growth	1.206044e-4
GO:0045765	regulation of angiogenesis	1.220754e-4
GO:0031111	negative regulation of microtubule polymerization or depolymerization	1.228243e-4
GO:0043112	receptor metabolic process	1.266351e-4
GO:0043206	fibril organization	1.277429e-4
GO:0071705	nitrogen compound transport	1.287335e-4
GO:0051646	mitochondrion localization	1.305272e-4
GO:0009308	amine metabolic process	1.326538e-4
GO:0070665	positive regulation of leukocyte proliferation	1.334535e-4
GO:0030910	olfactory placode formation	1.371142e-4
GO:0019098	reproductive behavior	1.396141e-4
GO:0006897	endocytosis	1.398242e-4
GO:0002637	regulation of immunoglobulin production	1.463480e-4
GO:0042554	superoxide anion generation	1.497050e-4
GO:0009966	regulation of signal transduction	1.508080e-4
GO:0002262	myeloid cell homeostasis	1.515334e-4
GO:0042628	mating plug formation	1.556115e-4
GO:0002768	immune response-regulating cell surface receptor signaling pathway	1.581266e-4
GO:0033363	secretory granule organization	1.594973e-4
GO:2000353	positive regulation of endothelial cell apoptosis	1.618381e-4
GO:0015860	purine nucleoside transport	1.618381e-4
GO:0021543	pallium development	1.633505e-4
GO:0006958	complement activation, classical pathway	1.649840e-4
GO:0051179	localization	1.654155e-4
GO:0050854	regulation of antigen receptor-mediated signaling pathway	1.693704e-4
GO:0051964	negative regulation of synapse assembly	1.721191e-4
GO:0050671	positive regulation of lymphocyte proliferation	1.731426e-4
GO:0007017	microtubule-based process	1.733165e-4
GO:0002520	immune system development	1.807062e-4
GO:0043954	cellular component maintenance	1.855727e-4
GO:0060736	prostate gland growth	1.902586e-4
GO:0006968	cellular defense response	1.977011e-4
GO:0035645	enteric smooth muscle cell differentiation	1.982626e-4
GO:0007497	posterior midgut development	1.982626e-4
GO:0002831	regulation of response to biotic stimulus	2.015718e-4
GO:0032836	glomerular basement membrane development	2.022439e-4
GO:0042698	ovulation cycle	2.024697e-4
GO:0032946	positive regulation of mononuclear cell proliferation	2.029671e-4
GO:0030097	hemopoiesis	2.050432e-4
GO:0050708	regulation of protein secretion	2.055817e-4
GO:0008406	gonad development	2.155145e-4
GO:0035458	cellular response to interferon-beta	2.158792e-4
GO:0071732	cellular response to nitric oxide	2.158792e-4
GO:0000003	reproduction	2.181383e-4
GO:0040008	regulation of growth	2.189164e-4
GO:0032330	regulation of chondrocyte differentiation	2.214453e-4
GO:0007416	synapse assembly	2.226143e-4
GO:0045766	positive regulation of angiogenesis	2.273862e-4
GO:0002366	leukocyte activation involved in immune response	2.273862e-4
GO:0021629	olfactory nerve structural organization	2.322571e-4
GO:0010957	negative regulation of vitamin D biosynthetic process	2.322571e-4
GO:0030316	osteoclast differentiation	2.322914e-4
GO:0001706	endoderm formation	2.343551e-4
GO:0060119	inner ear receptor cell development	2.347999e-4
GO:0002720	positive regulation of cytokine production involved in immune response	2.347999e-4
GO:0051240	positive regulation of multicellular organismal process	2.377968e-4
GO:0048563	post-embryonic organ morphogenesis	2.429725e-4
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	2.429725e-4
GO:0009267	cellular response to starvation	2.433632e-4
GO:0030888	regulation of B cell proliferation	2.486701e-4
GO:0048841	regulation of axon extension involved in axon guidance	2.537918e-4
GO:0048843	negative regulation of axon extension involved in axon guidance	2.589593e-4
GO:0023051	regulation of signaling	2.600716e-4
GO:0071842	cellular component organization at cellular level	2.600972e-4
GO:0031669	cellular response to nutrient levels	2.603428e-4
GO:2000351	regulation of endothelial cell apoptosis	2.612049e-4
GO:0009266	response to temperature stimulus	2.661423e-4
GO:0022414	reproductive process	2.695577e-4
GO:0007167	enzyme linked receptor protein signaling pathway	2.720599e-4
GO:0009653	anatomical structure morphogenesis	2.779717e-4
GO:0032102	negative regulation of response to external stimulus	2.826803e-4
GO:0030517	negative regulation of axon extension	2.848649e-4
GO:0002360	T cell lineage commitment	2.862173e-4
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	2.888860e-4
GO:0048511	rhythmic process	2.909258e-4
GO:0006583	melanin biosynthetic process from tyrosine	2.973336e-4
GO:0061024	membrane organization	2.974758e-4
GO:0032886	regulation of microtubule-based process	2.980680e-4
GO:0090200	positive regulation of release of cytochrome c from mitochondria	2.992843e-4
GO:0006686	sphingomyelin biosynthetic process	2.992843e-4
GO:0032880	regulation of protein localization	3.027423e-4
GO:0007283	spermatogenesis	3.079539e-4
GO:0006885	regulation of pH	3.129662e-4
GO:0060741	prostate gland stromal morphogenesis	3.157824e-4
GO:0009082	branched chain family amino acid biosynthetic process	3.182929e-4
GO:0030212	hyaluronan metabolic process	3.203004e-4
GO:0060751	branch elongation involved in mammary gland duct branching	3.332083e-4
GO:0051454	intracellular pH elevation	3.372427e-4
GO:0072592	oxygen metabolic process	3.372427e-4
GO:0010817	regulation of hormone levels	3.410835e-4
GO:0030260	entry into host cell	3.413505e-4
GO:0046395	carboxylic acid catabolic process	3.468561e-4
GO:0010894	negative regulation of steroid biosynthetic process	3.515638e-4
GO:0051346	negative regulation of hydrolase activity	3.521456e-4
GO:0006643	membrane lipid metabolic process	3.550389e-4
GO:0060068	vagina development	3.579274e-4
GO:0000238	zygotene	3.639328e-4
GO:0035106	operant conditioning	3.639328e-4
GO:0051234	establishment of localization	3.667168e-4
GO:0050793	regulation of developmental process	3.682667e-4
GO:0048731	system development	3.706750e-4
GO:0016044	cellular membrane organization	3.774467e-4
GO:0032509	endosome transport via multivesicular body sorting pathway	3.809244e-4
GO:2000177	regulation of neural precursor cell proliferation	3.875154e-4
GO:0030217	T cell differentiation	3.903204e-4
GO:0061039	ovum-producing ovary development	3.906975e-4
GO:0002833	positive regulation of response to biotic stimulus	3.920203e-4
GO:0032464	positive regulation of protein homooligomerization	3.941752e-4
GO:0021843	substrate-independent telencephalic tangential interneuron migration	3.945115e-4
GO:0051146	striated muscle cell differentiation	3.985720e-4
GO:0042404	thyroid hormone catabolic process	4.159422e-4
GO:0032526	response to retinoic acid	4.473641e-4
GO:0051659	maintenance of mitochondrion location	4.495806e-4
GO:0007623	circadian rhythm	4.506078e-4
GO:0051336	regulation of hydrolase activity	4.533239e-4
GO:0045541	negative regulation of cholesterol biosynthetic process	4.551747e-4
GO:0035644	phosphoanandamide dephosphorylation	4.551747e-4
GO:0045767	regulation of anti-apoptosis	4.553409e-4
GO:0032200	telomere organization	4.560749e-4
GO:0048521	negative regulation of behavior	4.659708e-4
GO:0016445	somatic diversification of immunoglobulins	4.704272e-4
GO:0001919	regulation of receptor recycling	4.710093e-4
GO:0016553	base conversion or substitution editing	4.889709e-4
GO:0006972	hyperosmotic response	4.897070e-4
GO:0009593	detection of chemical stimulus	4.913024e-4
GO:0043252	sodium-independent organic anion transport	4.928727e-4
GO:0016078	tRNA catabolic process	4.928727e-4
GO:0001682	tRNA 5'-leader removal	4.928727e-4
GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA	4.928727e-4
GO:0060154	cellular process regulating host cell cycle in response to virus	4.942657e-4
GO:0034198	cellular response to amino acid starvation	5.012433e-4
GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis	5.012433e-4
GO:0051657	maintenance of organelle location	5.078607e-4
GO:0045346	regulation of MHC class II biosynthetic process	5.141710e-4
GO:0051701	interaction with host	5.380635e-4
GO:0009181	purine ribonucleoside diphosphate catabolic process	5.401574e-4
GO:0010035	response to inorganic substance	5.430008e-4
GO:0006022	aminoglycan metabolic process	5.431661e-4
GO:0032878	regulation of establishment or maintenance of cell polarity	5.597876e-4
GO:0070201	regulation of establishment of protein localization	5.678884e-4
GO:0007157	heterophilic cell-cell adhesion	5.769508e-4
GO:0035815	positive regulation of renal sodium excretion	5.830241e-4
GO:0048385	regulation of retinoic acid receptor signaling pathway	5.853878e-4
GO:0048518	positive regulation of biological process	5.928388e-4
GO:0055006	cardiac cell development	5.974776e-4
GO:0033189	response to vitamin A	5.975667e-4
GO:0051917	regulation of fibrinolysis	6.059202e-4
GO:0045619	regulation of lymphocyte differentiation	6.092870e-4
GO:0014043	negative regulation of neuron maturation	6.152628e-4
GO:0050864	regulation of B cell activation	6.190065e-4
GO:0033687	osteoblast proliferation	6.199867e-4
GO:0048640	negative regulation of developmental growth	6.271816e-4
GO:0001701	in utero embryonic development	6.326361e-4
GO:0043901	negative regulation of multi-organism process	6.437933e-4
GO:0042167	heme catabolic process	6.460741e-4
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	6.460741e-4
GO:0048145	regulation of fibroblast proliferation	6.474175e-4
GO:0000723	telomere maintenance	6.497857e-4
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	6.518294e-4
GO:0060122	inner ear receptor stereocilium organization	6.547037e-4
GO:0051668	localization within membrane	6.626747e-4
GO:0045588	positive regulation of gamma-delta T cell differentiation	6.727367e-4
GO:0006637	acyl-CoA metabolic process	6.727367e-4
GO:0046548	retinal rod cell development	6.800610e-4
GO:0034103	regulation of tissue remodeling	6.826143e-4
GO:0003008	system process	6.875487e-4
GO:0002695	negative regulation of leukocyte activation	6.900060e-4
GO:0006784	heme a biosynthetic process	6.913523e-4
GO:0050848	regulation of calcium-mediated signaling	7.060382e-4
GO:0001906	cell killing	7.190702e-4
GO:0045580	regulation of T cell differentiation	7.220985e-4
GO:0022010	central nervous system myelination	7.231455e-4
GO:0009306	protein secretion	7.294047e-4
GO:0033152	immunoglobulin V(D)J recombination	7.348210e-4
GO:0044281	small molecule metabolic process	7.378488e-4
GO:0043242	negative regulation of protein complex disassembly	7.387367e-4
GO:0033273	response to vitamin	7.468610e-4
GO:0010038	response to metal ion	7.529237e-4
GO:0050778	positive regulation of immune response	7.663396e-4
GO:0014904	myotube cell development	7.678873e-4
GO:0016447	somatic recombination of immunoglobulin gene segments	7.691377e-4
GO:0044106	cellular amine metabolic process	7.804710e-4
GO:0045332	phospholipid translocation	7.903137e-4
GO:0006959	humoral immune response	8.067837e-4
GO:0046545	development of primary female sexual characteristics	8.108510e-4
GO:0034341	response to interferon-gamma	8.117460e-4
GO:0009408	response to heat	8.140666e-4
GO:0002429	immune response-activating cell surface receptor signaling pathway	8.274840e-4
GO:0051223	regulation of protein transport	8.346839e-4
GO:2000741	positive regulation of mesenchymal stem cell differentiation	8.443448e-4
GO:0002358	B cell homeostatic proliferation	8.483037e-4
GO:0015805	S-adenosylmethionine transport	8.584947e-4
GO:0050790	regulation of catalytic activity	8.594122e-4
GO:0043406	positive regulation of MAP kinase activity	8.603972e-4
GO:0034201	response to oleic acid	8.694936e-4
GO:0019439	aromatic compound catabolic process	8.812247e-4
GO:0046627	negative regulation of insulin receptor signaling pathway	8.888118e-4
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	9.001763e-4
GO:0048468	cell development	9.011721e-4
GO:0032653	regulation of interleukin-10 production	9.058346e-4
GO:0042448	progesterone metabolic process	9.116123e-4
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	9.148069e-4
GO:0038027	apolipoprotein A-I-mediated signaling pathway	9.512807e-4
GO:0042938	dipeptide transport	9.512807e-4
GO:0033598	mammary gland epithelial cell proliferation	9.526298e-4
GO:2000179	positive regulation of neural precursor cell proliferation	9.540661e-4
GO:0006911	phagocytosis, engulfment	9.568826e-4
GO:0045591	positive regulation of regulatory T cell differentiation	9.577591e-4
GO:0045597	positive regulation of cell differentiation	9.592771e-4
GO:0050851	antigen receptor-mediated signaling pathway	9.662954e-4
GO:0001649	osteoblast differentiation	9.741156e-4
GO:0002250	adaptive immune response	9.742825e-4
GO:0048592	eye morphogenesis	9.757494e-4
GO:0033364	mast cell secretory granule organization	9.804714e-4
GO:0000733	DNA strand renaturation	9.804714e-4
GO:0071879	positive regulation of adrenergic receptor signaling pathway	9.872089e-4
GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	9.872089e-4
GO:0010821	regulation of mitochondrion organization	9.906239e-4
GO:0046110	xanthine metabolic process	9.928161e-4
GO:0035129	post-embryonic hindlimb morphogenesis	1.007020e-3
GO:0042219	cellular modified amino acid catabolic process	1.013260e-3
GO:0051250	negative regulation of lymphocyte activation	1.023782e-3
GO:0008585	female gonad development	1.023782e-3
GO:0090287	regulation of cellular response to growth factor stimulus	1.025527e-3
GO:0071305	cellular response to vitamin D	1.031088e-3
GO:0046209	nitric oxide metabolic process	1.031088e-3
GO:0032675	regulation of interleukin-6 production	1.041178e-3
GO:0050866	negative regulation of cell activation	1.056882e-3
GO:0048608	reproductive structure development	1.060617e-3
GO:0051856	adhesion to symbiont	1.073854e-3
GO:0060042	retina morphogenesis in camera-type eye	1.083706e-3
GO:0043064	flagellum organization	1.091618e-3
GO:0043623	cellular protein complex assembly	1.096131e-3
GO:0045065	cytotoxic T cell differentiation	1.104127e-3
GO:0051023	regulation of immunoglobulin secretion	1.133064e-3
GO:0032733	positive regulation of interleukin-10 production	1.142882e-3
GO:0010575	positive regulation vascular endothelial growth factor production	1.143564e-3
GO:0033865	nucleoside bisphosphate metabolic process	1.143633e-3
GO:0048812	neuron projection morphogenesis	1.148563e-3
GO:0050856	regulation of T cell receptor signaling pathway	1.163779e-3
GO:0006810	transport	1.184813e-3
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	1.193550e-3
GO:0045401	positive regulation of interleukin-3 biosynthetic process	1.193550e-3
GO:0050973	detection of mechanical stimulus involved in equilibrioception	1.226422e-3
GO:0007275	multicellular organismal development	1.253759e-3
GO:0090174	organelle membrane fusion	1.259745e-3