Novel motif:101

name:	motif101_NAGCAASA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0002376	immune system process	3.571206e-20
GO:0009611	response to wounding	7.331527e-17
GO:0050896	response to stimulus	1.318891e-16
GO:0030240	skeletal muscle thin filament assembly	2.626191e-16
GO:0035051	cardiac cell differentiation	1.717857e-15
GO:0042221	response to chemical stimulus	6.895687e-15
GO:0048769	sarcomerogenesis	2.519159e-14
GO:0006950	response to stress	2.783558e-14
GO:0000070	mitotic sister chromatid segregation	2.853502e-14
GO:0000819	sister chromatid segregation	5.575112e-14
GO:0007076	mitotic chromosome condensation	6.078039e-14
GO:0055007	cardiac muscle cell differentiation	1.114150e-13
GO:0045214	sarcomere organization	1.191810e-13
GO:0032501	multicellular organismal process	1.289020e-13
GO:0006928	cellular component movement	1.330560e-12
GO:0055013	cardiac muscle cell development	3.806903e-12
GO:0065008	regulation of biological quality	4.640576e-12
GO:0042060	wound healing	5.394784e-12
GO:0014866	skeletal myofibril assembly	6.070081e-12
GO:0006952	defense response	8.954094e-12
GO:0001775	cell activation	5.170603e-11
GO:0030261	chromosome condensation	5.832828e-11
GO:0007517	muscle organ development	5.856563e-11
GO:0007596	blood coagulation	5.907555e-11
GO:0030241	skeletal muscle myosin thick filament assembly	7.350131e-11
GO:0007067	mitosis	8.172990e-11
GO:0065007	biological regulation	8.736302e-11
GO:0006629	lipid metabolic process	8.812830e-11
GO:0055003	cardiac myofibril assembly	9.338291e-11
GO:0000087	M phase of mitotic cell cycle	9.687789e-11
GO:0007599	hemostasis	1.124344e-10
GO:0048285	organelle fission	1.385706e-10
GO:0002520	immune system development	2.025120e-10
GO:0060537	muscle tissue development	2.429660e-10
GO:0006323	DNA packaging	3.496480e-10
GO:0048584	positive regulation of response to stimulus	6.249183e-10
GO:0014706	striated muscle tissue development	7.091742e-10
GO:0061061	muscle structure development	7.877013e-10
GO:0009888	tissue development	1.044949e-9
GO:0006941	striated muscle contraction	1.095592e-9
GO:0050794	regulation of cellular process	1.112449e-9
GO:0002700	regulation of production of molecular mediator of immune response	1.764282e-9
GO:0048534	hemopoietic or lymphoid organ development	2.186326e-9
GO:0048513	organ development	2.618634e-9
GO:0002694	regulation of leukocyte activation	3.552057e-9
GO:0051606	detection of stimulus	3.640761e-9
GO:0050878	regulation of body fluid levels	3.722324e-9
GO:0006954	inflammatory response	4.701393e-9
GO:0048729	tissue morphogenesis	5.878648e-9
GO:0002684	positive regulation of immune system process	5.958999e-9
GO:0030097	hemopoiesis	6.049045e-9
GO:0043623	cellular protein complex assembly	7.005678e-9
GO:0051179	localization	1.028802e-8
GO:0048738	cardiac muscle tissue development	1.356380e-8
GO:0008284	positive regulation of cell proliferation	1.367933e-8
GO:0006955	immune response	1.493291e-8
GO:0030049	muscle filament sliding	1.702923e-8
GO:0048731	system development	1.750715e-8
GO:0051240	positive regulation of multicellular organismal process	1.753364e-8
GO:0070252	actin-mediated cell contraction	1.827793e-8
GO:0050865	regulation of cell activation	1.836302e-8
GO:0034622	cellular macromolecular complex assembly	2.263182e-8
GO:0051046	regulation of secretion	2.292842e-8
GO:0071103	DNA conformation change	2.786916e-8
GO:0030168	platelet activation	2.947879e-8
GO:0031032	actomyosin structure organization	3.339299e-8
GO:0050789	regulation of biological process	3.350192e-8
GO:0042692	muscle cell differentiation	3.401154e-8
GO:0050708	regulation of protein secretion	4.239183e-8
GO:0048856	anatomical structure development	4.262016e-8
GO:0048646	anatomical structure formation involved in morphogenesis	5.444863e-8
GO:0007628	adult walking behavior	5.782824e-8
GO:0061005	cell differentiation involved in kidney development	6.498711e-8
GO:0007154	cell communication	7.812146e-8
GO:0007507	heart development	8.067820e-8
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	8.262510e-8
GO:0055001	muscle cell development	8.338917e-8
GO:0030239	myofibril assembly	9.135878e-8
GO:0032502	developmental process	9.334661e-8
GO:0007208	activation of phospholipase C activity by serotonin receptor signaling pathway	9.800044e-8
GO:0030048	actin filament-based movement	1.171816e-7
GO:0019637	organophosphate metabolic process	1.203916e-7
GO:0061036	positive regulation of cartilage development	1.209473e-7
GO:0060011	Sertoli cell proliferation	1.232336e-7
GO:0019674	NAD metabolic process	1.242987e-7
GO:0048732	gland development	1.264762e-7
GO:0034139	regulation of toll-like receptor 3 signaling pathway	1.368848e-7
GO:0032652	regulation of interleukin-1 production	1.575906e-7
GO:0051146	striated muscle cell differentiation	1.731366e-7
GO:0048870	cell motility	1.835319e-7
GO:0007275	multicellular organismal development	1.930996e-7
GO:0048644	muscle organ morphogenesis	1.948037e-7
GO:0002702	positive regulation of production of molecular mediator of immune response	1.970069e-7
GO:0042127	regulation of cell proliferation	1.977162e-7
GO:0009605	response to external stimulus	2.005509e-7
GO:0061088	regulation of sequestering of zinc ion	2.005682e-7
GO:0060415	muscle tissue morphogenesis	2.244084e-7
GO:0002718	regulation of cytokine production involved in immune response	2.501148e-7
GO:0048853	forebrain morphogenesis	3.200203e-7
GO:0040011	locomotion	3.208930e-7
GO:0023052	signaling	3.317265e-7
GO:0032691	negative regulation of interleukin-1 beta production	3.336638e-7
GO:0055008	cardiac muscle tissue morphogenesis	3.512029e-7
GO:0032692	negative regulation of interleukin-1 production	3.736380e-7
GO:0022612	gland morphogenesis	3.939797e-7
GO:0048747	muscle fiber development	4.399407e-7
GO:0051188	cofactor biosynthetic process	4.695489e-7
GO:0009435	NAD biosynthetic process	4.705540e-7
GO:0048518	positive regulation of biological process	4.758503e-7
GO:0002696	positive regulation of leukocyte activation	4.773575e-7
GO:0051716	cellular response to stimulus	4.885878e-7
GO:0006733	oxidoreduction coenzyme metabolic process	5.487724e-7
GO:0048739	cardiac muscle fiber development	6.003790e-7
GO:0009617	response to bacterium	6.365781e-7
GO:0050867	positive regulation of cell activation	6.714191e-7
GO:0007166	cell surface receptor linked signaling pathway	7.542926e-7
GO:0040008	regulation of growth	7.724992e-7
GO:0016477	cell migration	7.782506e-7
GO:0030185	nitric oxide transport	7.786264e-7
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	9.213246e-7
GO:0000278	mitotic cell cycle	9.257948e-7
GO:0051704	multi-organism process	9.671145e-7
GO:0050776	regulation of immune response	1.016300e-6
GO:0006783	heme biosynthetic process	1.029891e-6
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	1.033023e-6
GO:0051047	positive regulation of secretion	1.084966e-6
GO:0019359	nicotinamide nucleotide biosynthetic process	1.121946e-6
GO:0002244	hemopoietic progenitor cell differentiation	1.134595e-6
GO:0034141	positive regulation of toll-like receptor 3 signaling pathway	1.185111e-6
GO:0065003	macromolecular complex assembly	1.213488e-6
GO:0002320	lymphoid progenitor cell differentiation	1.295311e-6
GO:0034754	cellular hormone metabolic process	1.341968e-6
GO:0021953	central nervous system neuron differentiation	1.346066e-6
GO:0002537	nitric oxide production involved in inflammatory response	1.384395e-6
GO:0032651	regulation of interleukin-1 beta production	1.420543e-6
GO:0060523	prostate epithelial cord elongation	1.447963e-6
GO:0003183	mitral valve morphogenesis	1.518419e-6
GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis	1.542705e-6
GO:0035385	Roundabout signaling pathway	1.604807e-6
GO:0002682	regulation of immune system process	1.622793e-6
GO:0048522	positive regulation of cellular process	1.623545e-6
GO:0034121	regulation of toll-like receptor signaling pathway	1.775252e-6
GO:0003007	heart morphogenesis	1.800086e-6
GO:0002576	platelet degranulation	1.851300e-6
GO:0055002	striated muscle cell development	1.875204e-6
GO:0010927	cellular component assembly involved in morphogenesis	1.956634e-6
GO:0050727	regulation of inflammatory response	1.974627e-6
GO:0007320	insemination	2.020257e-6
GO:0072112	glomerular visceral epithelial cell differentiation	2.020926e-6
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.086236e-6
GO:0046546	development of primary male sexual characteristics	2.155175e-6
GO:0045321	leukocyte activation	2.155531e-6
GO:0048583	regulation of response to stimulus	2.252026e-6
GO:0034143	regulation of toll-like receptor 4 signaling pathway	2.313065e-6
GO:0000921	septin ring assembly	2.713685e-6
GO:0051290	protein heterotetramerization	2.909118e-6
GO:0060413	atrial septum morphogenesis	2.954820e-6
GO:0003008	system process	2.978660e-6
GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	3.175288e-6
GO:0046496	nicotinamide nucleotide metabolic process	3.321948e-6
GO:0023056	positive regulation of signaling	3.367314e-6
GO:0035850	epithelial cell differentiation involved in kidney development	3.438913e-6
GO:0060907	positive regulation of macrophage cytokine production	3.502281e-6
GO:0003357	noradrenergic neuron differentiation	3.527372e-6
GO:0050900	leukocyte migration	3.535965e-6
GO:0032940	secretion by cell	3.546041e-6
GO:0007186	G-protein coupled receptor protein signaling pathway	3.556465e-6
GO:0030325	adrenal gland development	3.575191e-6
GO:0007059	chromosome segregation	3.692148e-6
GO:0043587	tongue morphogenesis	4.053382e-6
GO:0007165	signal transduction	4.158884e-6
GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback	4.178679e-6
GO:0010817	regulation of hormone levels	4.323447e-6
GO:0032472	Golgi calcium ion transport	4.325628e-6
GO:0032468	Golgi calcium ion homeostasis	4.325628e-6
GO:0030026	cellular manganese ion homeostasis	4.325628e-6
GO:0020027	hemoglobin metabolic process	4.426015e-6
GO:0008610	lipid biosynthetic process	4.521373e-6
GO:0010647	positive regulation of cell communication	5.007316e-6
GO:0034621	cellular macromolecular complex subunit organization	5.025884e-6
GO:0030154	cell differentiation	5.098951e-6
GO:0019222	regulation of metabolic process	5.767096e-6
GO:0030890	positive regulation of B cell proliferation	5.806924e-6
GO:0060068	vagina development	5.845564e-6
GO:0044255	cellular lipid metabolic process	5.889709e-6
GO:0048608	reproductive structure development	6.332097e-6
GO:0006644	phospholipid metabolic process	6.375047e-6
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	6.551605e-6
GO:0035910	ascending aorta morphogenesis	6.551605e-6
GO:0007015	actin filament organization	6.631571e-6
GO:0032680	regulation of tumor necrosis factor production	6.668233e-6
GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	7.022373e-6
GO:0008207	C21-steroid hormone metabolic process	7.141698e-6
GO:0070374	positive regulation of ERK1 and ERK2 cascade	7.153163e-6
GO:0030595	leukocyte chemotaxis	7.490086e-6
GO:0019220	regulation of phosphate metabolic process	7.548345e-6
GO:0002252	immune effector process	7.596632e-6
GO:0051223	regulation of protein transport	7.667842e-6
GO:0071034	CUT catabolic process	7.850857e-6
GO:0045671	negative regulation of osteoclast differentiation	7.919774e-6
GO:0048519	negative regulation of biological process	8.203931e-6
GO:0048869	cellular developmental process	8.352208e-6
GO:0051249	regulation of lymphocyte activation	8.597097e-6
GO:0048598	embryonic morphogenesis	9.096645e-6
GO:0050906	detection of stimulus involved in sensory perception	9.698577e-6
GO:0002328	pro-B cell differentiation	9.924235e-6
GO:0072358	cardiovascular system development	1.033050e-5
GO:0002720	positive regulation of cytokine production involved in immune response	1.039172e-5
GO:0043549	regulation of kinase activity	1.064616e-5
GO:0021509	roof plate formation	1.166169e-5
GO:0006935	chemotaxis	1.177070e-5
GO:0009790	embryo development	1.193189e-5
GO:0048523	negative regulation of cellular process	1.250993e-5
GO:0010453	regulation of cell fate commitment	1.255568e-5
GO:0045137	development of primary sexual characteristics	1.277317e-5
GO:0015755	fructose transport	1.305931e-5
GO:0008584	male gonad development	1.311686e-5
GO:0010667	negative regulation of cardiac muscle cell apoptosis	1.369602e-5
GO:0021517	ventral spinal cord development	1.376340e-5
GO:0051186	cofactor metabolic process	1.381134e-5
GO:0070100	negative regulation of chemokine-mediated signaling pathway	1.420773e-5
GO:0001817	regulation of cytokine production	1.426831e-5
GO:0050778	positive regulation of immune response	1.430931e-5
GO:0006887	exocytosis	1.487161e-5
GO:0008152	metabolic process	1.513973e-5
GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.532346e-5
GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.532346e-5
GO:0051145	smooth muscle cell differentiation	1.554010e-5
GO:0051041	positive regulation of calcium-independent cell-cell adhesion	1.577067e-5
GO:0050902	leukocyte adhesive activation	1.577067e-5
GO:0009953	dorsal/ventral pattern formation	1.577858e-5
GO:0061035	regulation of cartilage development	1.617910e-5
GO:0009636	response to toxin	1.671639e-5
GO:0051592	response to calcium ion	1.682748e-5
GO:0051346	negative regulation of hydrolase activity	1.721275e-5
GO:0051234	establishment of localization	1.753380e-5
GO:0008202	steroid metabolic process	1.766810e-5
GO:0009581	detection of external stimulus	1.856024e-5
GO:0045338	farnesyl diphosphate metabolic process	1.872353e-5
GO:0044036	cell wall macromolecule metabolic process	1.907656e-5
GO:0009799	specification of symmetry	1.951930e-5
GO:0006694	steroid biosynthetic process	1.984512e-5
GO:0043933	macromolecular complex subunit organization	1.990254e-5
GO:0021680	cerebellar Purkinje cell layer development	2.000116e-5
GO:0070228	regulation of lymphocyte apoptosis	2.014658e-5
GO:0000416	positive regulation of histone H3-K36 methylation	2.033937e-5
GO:0050864	regulation of B cell activation	2.086695e-5
GO:0051239	regulation of multicellular organismal process	2.153923e-5
GO:0051050	positive regulation of transport	2.185435e-5
GO:0019932	second-messenger-mediated signaling	2.197695e-5
GO:0042742	defense response to bacterium	2.205313e-5
GO:0060538	skeletal muscle organ development	2.214950e-5
GO:0006116	NADH oxidation	2.299223e-5
GO:0050790	regulation of catalytic activity	2.314541e-5
GO:0001655	urogenital system development	2.319211e-5
GO:0030888	regulation of B cell proliferation	2.338488e-5
GO:0046661	male sex differentiation	2.390687e-5
GO:0019362	pyridine nucleotide metabolic process	2.415487e-5
GO:0034123	positive regulation of toll-like receptor signaling pathway	2.490392e-5
GO:0002548	monocyte chemotaxis	2.521704e-5
GO:0000279	M phase	2.589860e-5
GO:0010646	regulation of cell communication	2.626113e-5
GO:0031323	regulation of cellular metabolic process	2.640543e-5
GO:0051482	elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger	2.671531e-5
GO:0051338	regulation of transferase activity	2.733040e-5
GO:0006613	cotranslational protein targeting to membrane	2.753375e-5
GO:0046903	secretion	2.817476e-5
GO:0043310	negative regulation of eosinophil degranulation	2.930545e-5
GO:2000409	positive regulation of T cell extravasation	2.930545e-5
GO:0035705	T-helper 17 cell chemotaxis	2.930545e-5
GO:0035696	monocyte extravasation	2.930545e-5
GO:0010935	regulation of macrophage cytokine production	2.951808e-5
GO:0060055	angiogenesis involved in wound healing	2.960602e-5
GO:0051276	chromosome organization	3.042165e-5
GO:0030879	mammary gland development	3.109417e-5
GO:0030540	female genitalia development	3.212500e-5
GO:0045087	innate immune response	3.222063e-5
GO:0061156	pulmonary artery morphogenesis	3.255742e-5
GO:0042168	heme metabolic process	3.259028e-5
GO:0050974	detection of mechanical stimulus involved in sensory perception	3.374064e-5
GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity	3.379723e-5
GO:0006810	transport	3.385800e-5
GO:0007417	central nervous system development	3.530517e-5
GO:0048386	positive regulation of retinoic acid receptor signaling pathway	3.566544e-5
GO:0045859	regulation of protein kinase activity	3.570255e-5
GO:0032879	regulation of localization	3.586138e-5
GO:0048854	brain morphogenesis	3.727295e-5
GO:0006083	acetate metabolic process	3.740583e-5
GO:0006576	cellular biogenic amine metabolic process	3.851777e-5
GO:0008015	blood circulation	3.935296e-5
GO:0045359	positive regulation of interferon-beta biosynthetic process	4.058294e-5
GO:0008217	regulation of blood pressure	4.067917e-5
GO:0060191	regulation of lipase activity	4.174334e-5
GO:0042659	regulation of cell fate specification	4.259627e-5
GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly	4.299552e-5
GO:0006779	porphyrin-containing compound biosynthetic process	4.303091e-5
GO:0048468	cell development	4.556717e-5
GO:0051246	regulation of protein metabolic process	4.607088e-5
GO:0072592	oxygen metabolic process	4.742262e-5
GO:0008209	androgen metabolic process	4.761537e-5
GO:0035108	limb morphogenesis	4.808491e-5
GO:0046637	regulation of alpha-beta T cell differentiation	4.883937e-5
GO:0055114	oxidation-reduction process	4.957953e-5
GO:0065009	regulation of molecular function	5.085472e-5
GO:0003006	developmental process involved in reproduction	5.356212e-5
GO:0021860	pyramidal neuron development	5.356679e-5
GO:0050830	defense response to Gram-positive bacterium	5.411929e-5
GO:0006461	protein complex assembly	5.478809e-5
GO:0042445	hormone metabolic process	5.492006e-5
GO:0051707	response to other organism	5.494126e-5
GO:0060047	heart contraction	5.623162e-5
GO:0042953	lipoprotein transport	5.690979e-5
GO:0052572	response to host immune response	5.785869e-5
GO:0010464	regulation of mesenchymal cell proliferation	5.927772e-5
GO:0043129	surfactant homeostasis	6.131351e-5
GO:0000186	activation of MAPKK activity	6.234033e-5
GO:0003283	atrial septum development	6.274879e-5
GO:0030900	forebrain development	6.309657e-5
GO:0060440	trachea formation	6.310890e-5
GO:0045926	negative regulation of growth	6.338343e-5
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	6.381848e-5
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	6.381848e-5
GO:0016046	detection of fungus	6.381848e-5
GO:0010665	regulation of cardiac muscle cell apoptosis	6.384413e-5
GO:0070071	proton-transporting two-sector ATPase complex assembly	6.418303e-5
GO:0050793	regulation of developmental process	6.585259e-5
GO:0014059	regulation of dopamine secretion	6.721932e-5
GO:0021836	chemorepulsion involved in postnatal olfactory bulb interneuron migration	6.767986e-5
GO:0042592	homeostatic process	7.029510e-5
GO:0002699	positive regulation of immune effector process	7.090470e-5
GO:0070271	protein complex biogenesis	7.172943e-5
GO:0050714	positive regulation of protein secretion	7.204101e-5
GO:0009582	detection of abiotic stimulus	7.246824e-5
GO:0072199	regulation of mesenchymal cell proliferation involved in ureter development	7.302396e-5
GO:0060428	lung epithelium development	7.621040e-5
GO:0008283	cell proliferation	7.693173e-5
GO:0031399	regulation of protein modification process	7.893413e-5
GO:0018158	protein oxidation	7.924876e-5
GO:0030322	stabilization of membrane potential	7.924876e-5
GO:0045581	negative regulation of T cell differentiation	8.060957e-5
GO:0072124	regulation of glomerular mesangial cell proliferation	8.069975e-5
GO:0050433	regulation of catecholamine secretion	8.137831e-5
GO:0021798	forebrain dorsal/ventral pattern formation	8.166782e-5
GO:0071222	cellular response to lipopolysaccharide	8.253909e-5
GO:0032958	inositol phosphate biosynthetic process	8.424481e-5
GO:0032103	positive regulation of response to external stimulus	8.465327e-5
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	8.525477e-5
GO:0019233	sensory perception of pain	8.865228e-5
GO:0042733	embryonic digit morphogenesis	9.082924e-5
GO:0006996	organelle organization	9.098331e-5
GO:0070229	negative regulation of lymphocyte apoptosis	9.184632e-5
GO:0050707	regulation of cytokine secretion	9.345283e-5
GO:0071671	regulation of smooth muscle cell chemotaxis	9.374645e-5
GO:0010463	mesenchymal cell proliferation	9.438581e-5
GO:0060602	branch elongation of an epithelium	9.478423e-5
GO:0006778	porphyrin-containing compound metabolic process	9.547120e-5
GO:0030300	regulation of intestinal cholesterol absorption	9.578324e-5
GO:0006907	pinocytosis	9.578324e-5
GO:0045357	regulation of interferon-beta biosynthetic process	9.640915e-5
GO:0032074	negative regulation of nuclease activity	9.824984e-5
GO:0050720	interleukin-1 beta biosynthetic process	9.824984e-5
GO:0031324	negative regulation of cellular metabolic process	1.027803e-4
GO:0090265	positive regulation of immune complex clearance by monocytes and macrophages	1.032073e-4
GO:0090082	positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway	1.032073e-4
GO:0060004	reflex	1.040995e-4
GO:0060548	negative regulation of cell death	1.041664e-4
GO:0050877	neurological system process	1.058779e-4
GO:0010454	negative regulation of cell fate commitment	1.063260e-4
GO:0010921	regulation of phosphatase activity	1.063303e-4
GO:0060013	righting reflex	1.067807e-4
GO:0016043	cellular component organization	1.067927e-4
GO:0010038	response to metal ion	1.089445e-4
GO:0018963	phthalate metabolic process	1.108737e-4
GO:0071840	cellular component organization or biogenesis	1.109269e-4
GO:0046545	development of primary female sexual characteristics	1.128024e-4
GO:0002282	microglial cell activation involved in immune response	1.135922e-4
GO:0033133	positive regulation of glucokinase activity	1.136456e-4
GO:0070232	regulation of T cell apoptosis	1.147430e-4
GO:0003013	circulatory system process	1.152416e-4
GO:0019363	pyridine nucleotide biosynthetic process	1.159617e-4
GO:0008344	adult locomotory behavior	1.165929e-4
GO:0043410	positive regulation of MAPKKK cascade	1.201565e-4
GO:0043666	regulation of phosphoprotein phosphatase activity	1.203842e-4
GO:0061047	positive regulation of branching involved in lung morphogenesis	1.208729e-4
GO:0002274	myeloid leukocyte activation	1.209676e-4
GO:0051251	positive regulation of lymphocyte activation	1.218333e-4
GO:0010605	negative regulation of macromolecule metabolic process	1.231196e-4
GO:0072200	negative regulation of mesenchymal cell proliferation involved in ureter development	1.259300e-4
GO:0072198	mesenchymal cell proliferation involved in ureter development	1.259300e-4
GO:0072192	ureter epithelial cell differentiation	1.259300e-4
GO:0072138	mesenchymal cell proliferation involved in ureteric bud development	1.259300e-4
GO:0090194	negative regulation of glomerulus development	1.259300e-4
GO:2000137	negative regulation of cell proliferation involved in heart morphogenesis	1.259300e-4
GO:2000007	negative regulation of metanephric comma-shaped body morphogenesis	1.259300e-4
GO:2000005	negative regulation of metanephric S-shaped body morphogenesis	1.259300e-4
GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis	1.259300e-4
GO:0061151	BMP signaling pathway involved in renal system segmentation	1.259300e-4
GO:0072101	specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway	1.259300e-4
GO:0048392	intermediate mesodermal cell differentiation	1.259300e-4
GO:0035990	tendon cell differentiation	1.259300e-4
GO:0060503	bud dilation involved in lung branching	1.259300e-4
GO:0055020	positive regulation of cardiac muscle fiber development	1.259300e-4
GO:0061149	BMP signaling pathway involved in ureter morphogenesis	1.259300e-4
GO:0071893	BMP signaling pathway involved in nephric duct formation	1.259300e-4
GO:0072097	negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway	1.259300e-4
GO:0061155	pulmonary artery endothelial tube morphogenesis	1.259300e-4
GO:0060065	uterus development	1.274488e-4
GO:0030218	erythrocyte differentiation	1.285388e-4
GO:0030593	neutrophil chemotaxis	1.290510e-4
GO:0006465	signal peptide processing	1.336668e-4
GO:0010157	response to chlorate	1.357986e-4
GO:0042541	hemoglobin biosynthetic process	1.362063e-4
GO:0007548	sex differentiation	1.364857e-4
GO:0006875	cellular metal ion homeostasis	1.412032e-4
GO:0051971	positive regulation of transmission of nerve impulse	1.433567e-4
GO:0042574	retinal metabolic process	1.443582e-4
GO:0002764	immune response-regulating signaling pathway	1.470614e-4
GO:0060512	prostate gland morphogenesis	1.470781e-4
GO:0030098	lymphocyte differentiation	1.473582e-4
GO:0042325	regulation of phosphorylation	1.489824e-4
GO:0060737	prostate gland morphogenetic growth	1.531902e-4
GO:0009855	determination of bilateral symmetry	1.576262e-4
GO:0071371	cellular response to gonadotropin stimulus	1.587370e-4
GO:0031333	negative regulation of protein complex assembly	1.673798e-4
GO:0007565	female pregnancy	1.675620e-4
GO:0033152	immunoglobulin V(D)J recombination	1.678651e-4
GO:0060740	prostate gland epithelium morphogenesis	1.679493e-4
GO:0050871	positive regulation of B cell activation	1.702214e-4
GO:0048247	lymphocyte chemotaxis	1.714620e-4
GO:0051388	positive regulation of nerve growth factor receptor signaling pathway	1.722323e-4
GO:0035116	embryonic hindlimb morphogenesis	1.723005e-4
GO:0003219	cardiac right ventricle formation	1.740954e-4
GO:0046660	female sex differentiation	1.765886e-4
GO:0072193	ureter smooth muscle cell differentiation	1.771035e-4
GO:0032988	ribonucleoprotein complex disassembly	1.771035e-4
GO:0071219	cellular response to molecule of bacterial origin	1.772451e-4
GO:2000026	regulation of multicellular organismal development	1.776648e-4
GO:0030335	positive regulation of cell migration	1.787816e-4
GO:0003289	atrial septum primum morphogenesis	1.800620e-4
GO:0072190	ureter urothelium development	1.804377e-4
GO:0048389	intermediate mesoderm development	1.804377e-4
GO:0072098	anterior/posterior pattern specification involved in kidney development	1.804377e-4
GO:0060197	cloacal septation	1.823938e-4
GO:0022402	cell cycle process	1.840182e-4
GO:0042176	regulation of protein catabolic process	1.856869e-4
GO:0060174	limb bud formation	1.862392e-4
GO:0032185	septin cytoskeleton organization	1.905675e-4
GO:0043309	regulation of eosinophil degranulation	1.923232e-4
GO:0001812	positive regulation of type I hypersensitivity	1.923232e-4
GO:0009887	organ morphogenesis	1.962775e-4
GO:0009966	regulation of signal transduction	1.967961e-4
GO:0045900	negative regulation of translational elongation	2.005311e-4
GO:0080090	regulation of primary metabolic process	2.048627e-4
GO:0014009	glial cell proliferation	2.058406e-4
GO:0006026	aminoglycan catabolic process	2.058406e-4
GO:0031120	snRNA pseudouridine synthesis	2.071607e-4
GO:0006037	cell wall chitin metabolic process	2.071607e-4
GO:2001021	negative regulation of response to DNA damage stimulus	2.071736e-4
GO:0001819	positive regulation of cytokine production	2.074733e-4
GO:0032959	inositol trisphosphate biosynthetic process	2.077841e-4
GO:0009892	negative regulation of metabolic process	2.133008e-4
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	2.144902e-4
GO:0050678	regulation of epithelial cell proliferation	2.157630e-4
GO:0010923	negative regulation of phosphatase activity	2.157952e-4
GO:0042448	progesterone metabolic process	2.163877e-4
GO:2000027	regulation of organ morphogenesis	2.194751e-4
GO:0042534	regulation of tumor necrosis factor biosynthetic process	2.226317e-4
GO:0070243	regulation of thymocyte apoptosis	2.232823e-4
GO:0050709	negative regulation of protein secretion	2.238224e-4
GO:2000147	positive regulation of cell motility	2.254717e-4
GO:0021515	cell differentiation in spinal cord	2.281653e-4
GO:0060993	kidney morphogenesis	2.281653e-4
GO:0002757	immune response-activating signal transduction	2.299236e-4
GO:0002739	regulation of cytokine secretion involved in immune response	2.314653e-4
GO:0045732	positive regulation of protein catabolic process	2.322979e-4
GO:0021904	dorsal/ventral neural tube patterning	2.324568e-4
GO:0006259	DNA metabolic process	2.345623e-4
GO:0022403	cell cycle phase	2.351135e-4
GO:0060745	mammary gland branching involved in pregnancy	2.376841e-4
GO:0018130	heterocycle biosynthetic process	2.413920e-4
GO:0050806	positive regulation of synaptic transmission	2.465699e-4
GO:0009410	response to xenobiotic stimulus	2.476129e-4
GO:0003279	cardiac septum development	2.489130e-4
GO:0031646	positive regulation of neurological system process	2.491013e-4
GO:0042113	B cell activation	2.532162e-4
GO:0032760	positive regulation of tumor necrosis factor production	2.539320e-4
GO:0002281	macrophage activation involved in immune response	2.545576e-4
GO:0070372	regulation of ERK1 and ERK2 cascade	2.571473e-4
GO:0015671	oxygen transport	2.587031e-4
GO:0060687	regulation of branching involved in prostate gland morphogenesis	2.589513e-4
GO:0060255	regulation of macromolecule metabolic process	2.600638e-4
GO:0009967	positive regulation of signal transduction	2.622116e-4
GO:0002366	leukocyte activation involved in immune response	2.662890e-4
GO:0048585	negative regulation of response to stimulus	2.670132e-4
GO:0060173	limb development	2.706672e-4
GO:0003215	cardiac right ventricle morphogenesis	2.740761e-4
GO:0021537	telencephalon development	2.761936e-4
GO:0045123	cellular extravasation	2.779019e-4
GO:0031327	negative regulation of cellular biosynthetic process	2.806898e-4
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	2.816258e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0050863	regulation of T cell activation	1.031354e-10
GO:0002694	regulation of leukocyte activation	7.711890e-10
GO:0032722	positive regulation of chemokine production	4.251467e-9
GO:0009408	response to heat	4.909980e-9
GO:0050865	regulation of cell activation	1.611172e-8
GO:0051249	regulation of lymphocyte activation	4.811438e-8
GO:0034765	regulation of ion transmembrane transport	9.204097e-8
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	1.871589e-7
GO:0050870	positive regulation of T cell activation	2.027433e-7
GO:0050848	regulation of calcium-mediated signaling	2.205556e-7
GO:0050850	positive regulation of calcium-mediated signaling	4.940579e-7
GO:0010389	regulation of G2/M transition of mitotic cell cycle	5.488456e-7
GO:0032944	regulation of mononuclear cell proliferation	1.005728e-6
GO:0050670	regulation of lymphocyte proliferation	1.181439e-6
GO:0048632	negative regulation of skeletal muscle tissue growth	1.305702e-6
GO:0010501	RNA secondary structure unwinding	1.518253e-6
GO:0046634	regulation of alpha-beta T cell activation	1.614346e-6
GO:0051491	positive regulation of filopodium assembly	1.671071e-6
GO:0070663	regulation of leukocyte proliferation	1.884646e-6
GO:0035330	regulation of hippo signaling cascade	2.308119e-6
GO:0017145	stem cell division	2.377276e-6
GO:0034762	regulation of transmembrane transport	2.501584e-6
GO:0009266	response to temperature stimulus	3.230977e-6
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	3.335742e-6
GO:0030595	leukocyte chemotaxis	5.633715e-6
GO:0006952	defense response	6.496424e-6
GO:0051489	regulation of filopodium assembly	7.030158e-6
GO:0045730	respiratory burst	7.037762e-6
GO:0002683	negative regulation of immune system process	8.267729e-6
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	9.046992e-6
GO:0035691	macrophage migration inhibitory factor signaling pathway	9.126218e-6
GO:0006323	DNA packaging	1.064174e-5
GO:0016337	cell-cell adhesion	1.281699e-5
GO:0007156	homophilic cell adhesion	1.399452e-5
GO:0043269	regulation of ion transport	1.595282e-5
GO:0051919	positive regulation of fibrinolysis	1.890552e-5
GO:0032642	regulation of chemokine production	2.033754e-5
GO:0071103	DNA conformation change	2.141630e-5
GO:0051707	response to other organism	2.226303e-5
GO:0046640	regulation of alpha-beta T cell proliferation	2.235144e-5
GO:0009617	response to bacterium	2.310047e-5
GO:0042129	regulation of T cell proliferation	2.634508e-5
GO:0002682	regulation of immune system process	2.706871e-5
GO:0009607	response to biotic stimulus	2.849070e-5
GO:0001830	trophectodermal cell fate commitment	2.863554e-5
GO:0002695	negative regulation of leukocyte activation	2.942024e-5
GO:0071805	potassium ion transmembrane transport	3.098915e-5
GO:0051049	regulation of transport	3.567315e-5
GO:0014057	positive regulation of acetylcholine secretion	3.589526e-5
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	3.879236e-5
GO:0014741	negative regulation of muscle hypertrophy	4.003501e-5
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	4.026554e-5
GO:0072203	cell proliferation involved in metanephros development	4.383748e-5
GO:0002067	glandular epithelial cell differentiation	4.404968e-5
GO:0006813	potassium ion transport	4.578880e-5
GO:0032231	regulation of actin filament bundle assembly	5.483680e-5
GO:0030261	chromosome condensation	5.700177e-5
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	6.268192e-5
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	6.268192e-5
GO:0032707	negative regulation of interleukin-23 production	6.268192e-5
GO:0045362	positive regulation of interleukin-1 biosynthetic process	6.268192e-5
GO:0045625	regulation of T-helper 1 cell differentiation	6.380523e-5
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	6.520054e-5
GO:0042534	regulation of tumor necrosis factor biosynthetic process	6.629926e-5
GO:0090023	positive regulation of neutrophil chemotaxis	6.651331e-5
GO:0043366	beta selection	6.925988e-5
GO:0032946	positive regulation of mononuclear cell proliferation	7.037190e-5
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	7.340619e-5
GO:0032496	response to lipopolysaccharide	7.447954e-5
GO:0042108	positive regulation of cytokine biosynthetic process	7.503905e-5
GO:0051251	positive regulation of lymphocyte activation	7.810979e-5
GO:0050671	positive regulation of lymphocyte proliferation	8.235969e-5
GO:0042102	positive regulation of T cell proliferation	8.421740e-5
GO:0042660	positive regulation of cell fate specification	8.468182e-5
GO:0006906	vesicle fusion	8.789125e-5
GO:0034109	homotypic cell-cell adhesion	9.049034e-5
GO:0007018	microtubule-based movement	9.103510e-5
GO:0050867	positive regulation of cell activation	9.113976e-5
GO:0002696	positive regulation of leukocyte activation	9.227168e-5
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	9.559243e-5
GO:0002316	follicular B cell differentiation	9.628187e-5
GO:0070665	positive regulation of leukocyte proliferation	9.740001e-5
GO:0048103	somatic stem cell division	9.763913e-5
GO:0031099	regeneration	1.015317e-4
GO:0051607	defense response to virus	1.133741e-4
GO:0046635	positive regulation of alpha-beta T cell activation	1.173734e-4
GO:0046549	retinal cone cell development	1.303401e-4
GO:0006509	membrane protein ectodomain proteolysis	1.304452e-4
GO:0051250	negative regulation of lymphocyte activation	1.317122e-4
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	1.324114e-4
GO:0042297	vocal learning	1.342418e-4
GO:0051496	positive regulation of stress fiber assembly	1.408952e-4
GO:0072133	metanephric mesenchyme morphogenesis	1.411157e-4
GO:0030593	neutrophil chemotaxis	1.424391e-4
GO:0033619	membrane protein proteolysis	1.429856e-4
GO:0060326	cell chemotaxis	1.484816e-4
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	1.497662e-4
GO:0033003	regulation of mast cell activation	1.501936e-4
GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity	1.550076e-4
GO:0050900	leukocyte migration	1.619151e-4
GO:0050896	response to stimulus	1.678694e-4
GO:0002902	regulation of B cell apoptosis	1.708829e-4
GO:2000036	regulation of stem cell maintenance	1.754865e-4
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	1.835960e-4
GO:0032011	ARF protein signal transduction	1.863510e-4
GO:0043056	forward locomotion	1.888573e-4
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	1.941008e-4
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	1.941008e-4
GO:0007186	G-protein coupled receptor protein signaling pathway	1.981903e-4
GO:0072111	cell proliferation involved in kidney development	1.983594e-4
GO:0007155	cell adhesion	1.994751e-4
GO:0060907	positive regulation of macrophage cytokine production	2.063029e-4
GO:0051492	regulation of stress fiber assembly	2.065215e-4
GO:0051289	protein homotetramerization	2.146274e-4
GO:0042516	regulation of tyrosine phosphorylation of Stat3 protein	2.165577e-4
GO:0031344	regulation of cell projection organization	2.212966e-4
GO:0060969	negative regulation of gene silencing	2.224888e-4
GO:0002825	regulation of T-helper 1 type immune response	2.276596e-4
GO:0022610	biological adhesion	2.374867e-4
GO:0051704	multi-organism process	2.566977e-4
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	2.571460e-4
GO:0045401	positive regulation of interleukin-3 biosynthetic process	2.571460e-4
GO:0051085	chaperone mediated protein folding requiring cofactor	2.629253e-4
GO:0090022	regulation of neutrophil chemotaxis	2.694333e-4
GO:0001961	positive regulation of cytokine-mediated signaling pathway	2.714254e-4
GO:0006278	RNA-dependent DNA replication	2.756103e-4
GO:0003333	amino acid transmembrane transport	2.938914e-4
GO:0032957	inositol trisphosphate metabolic process	3.064307e-4
GO:0035588	G-protein coupled purinergic receptor signaling pathway	3.120720e-4
GO:0001578	microtubule bundle formation	3.127009e-4
GO:0000027	ribosomal large subunit assembly	3.308566e-4
GO:0042110	T cell activation	3.322708e-4
GO:0014056	regulation of acetylcholine secretion	3.460498e-4
GO:0050866	negative regulation of cell activation	3.553608e-4
GO:0006950	response to stress	3.605159e-4
GO:0032237	activation of store-operated calcium channel activity	3.669918e-4
GO:0002237	response to molecule of bacterial origin	3.759829e-4
GO:0009138	pyrimidine nucleoside diphosphate metabolic process	3.790025e-4
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	3.812191e-4
GO:0048683	regulation of collateral sprouting of intact axon in response to injury	3.812435e-4
GO:0007638	mechanosensory behavior	3.940059e-4
GO:0050920	regulation of chemotaxis	3.961609e-4
GO:0030182	neuron differentiation	4.101100e-4
GO:0002040	sprouting angiogenesis	4.319776e-4
GO:0051932	synaptic transmission, GABAergic	4.342684e-4
GO:0046627	negative regulation of insulin receptor signaling pathway	4.377441e-4
GO:0050714	positive regulation of protein secretion	4.416878e-4
GO:0042221	response to chemical stimulus	4.465731e-4
GO:0060742	epithelial cell differentiation involved in prostate gland development	4.477414e-4
GO:0002313	mature B cell differentiation involved in immune response	4.500952e-4
GO:0050868	negative regulation of T cell activation	4.537032e-4
GO:0006935	chemotaxis	4.622527e-4
GO:0008090	retrograde axon cargo transport	4.821499e-4
GO:0006837	serotonin transport	4.821499e-4
GO:0010867	positive regulation of triglyceride biosynthetic process	4.974557e-4
GO:0010310	regulation of hydrogen peroxide metabolic process	4.974557e-4
GO:0046636	negative regulation of alpha-beta T cell activation	5.000667e-4
GO:0002544	chronic inflammatory response	5.106836e-4
GO:0019805	quinolinate biosynthetic process	5.283317e-4
GO:0019731	antibacterial humoral response	5.287188e-4
GO:0032959	inositol trisphosphate biosynthetic process	5.491853e-4
GO:0046427	positive regulation of JAK-STAT cascade	5.498693e-4
GO:0006694	steroid biosynthetic process	5.506279e-4
GO:0014807	regulation of somitogenesis	5.522696e-4
GO:0003270	Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation	5.522696e-4
GO:0008206	bile acid metabolic process	5.533288e-4
GO:0042330	taxis	5.667729e-4
GO:0060122	inner ear receptor stereocilium organization	5.745520e-4
GO:0030217	T cell differentiation	5.802687e-4
GO:0046641	positive regulation of alpha-beta T cell proliferation	5.887880e-4
GO:0032233	positive regulation of actin filament bundle assembly	5.998161e-4
GO:0061386	closure of optic fissure	6.046679e-4
GO:0035332	positive regulation of hippo signaling cascade	6.046679e-4
GO:0006233	dTDP biosynthetic process	6.046679e-4
GO:0071674	mononuclear cell migration	6.316754e-4
GO:0003094	glomerular filtration	6.316754e-4
GO:0032958	inositol phosphate biosynthetic process	6.476352e-4
GO:0045059	positive thymic T cell selection	6.528147e-4
GO:0031346	positive regulation of cell projection organization	6.647901e-4
GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	6.846787e-4
GO:0044259	multicellular organismal macromolecule metabolic process	6.935448e-4
GO:0055003	cardiac myofibril assembly	7.147033e-4
GO:0007341	penetration of zona pellucida	7.360970e-4
GO:0045621	positive regulation of lymphocyte differentiation	7.544392e-4
GO:0070306	lens fiber cell differentiation	7.576090e-4
GO:0002526	acute inflammatory response	7.594984e-4
GO:0070229	negative regulation of lymphocyte apoptosis	7.640459e-4
GO:0060760	positive regulation of response to cytokine stimulus	7.650459e-4
GO:0032963	collagen metabolic process	7.769399e-4
GO:0014010	Schwann cell proliferation	7.791530e-4
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	7.958758e-4
GO:0045058	T cell selection	8.033112e-4
GO:0070236	negative regulation of activation-induced cell death of T cells	8.150906e-4
GO:0070970	interleukin-2 secretion	8.150906e-4
GO:0060253	negative regulation of glial cell proliferation	8.227834e-4
GO:0033058	directional locomotion	8.266416e-4
GO:0050906	detection of stimulus involved in sensory perception	8.328608e-4
GO:0071223	cellular response to lipoteichoic acid	8.337010e-4
GO:0006568	tryptophan metabolic process	8.337010e-4
GO:0046425	regulation of JAK-STAT cascade	8.493343e-4
GO:0032700	negative regulation of interleukin-17 production	8.624591e-4
GO:0014732	skeletal muscle atrophy	8.625090e-4
GO:0006000	fructose metabolic process	8.735132e-4
GO:0072143	mesangial cell development	8.964698e-4
GO:0031935	regulation of chromatin silencing	8.964698e-4
GO:0014823	response to activity	9.183056e-4
GO:0034728	nucleosome organization	9.552372e-4
GO:0007567	parturition	9.909873e-4
GO:0072076	nephrogenic mesenchyme development	1.001814e-3
GO:0061143	alveolar primary septum development	1.001901e-3
GO:0072134	nephrogenic mesenchyme morphogenesis	1.001901e-3
GO:0031936	negative regulation of chromatin silencing	1.012826e-3
GO:0007285	primary spermatocyte growth	1.019261e-3
GO:2000107	negative regulation of leukocyte apoptosis	1.028750e-3
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	1.036880e-3
GO:0060137	maternal process involved in parturition	1.089899e-3
GO:0060491	regulation of cell projection assembly	1.121418e-3
GO:0051240	positive regulation of multicellular organismal process	1.166391e-3
GO:0071295	cellular response to vitamin	1.174159e-3
GO:0002720	positive regulation of cytokine production involved in immune response	1.206835e-3
GO:0035887	aortic smooth muscle cell differentiation	1.261106e-3
GO:0050921	positive regulation of chemotaxis	1.264227e-3
GO:0002335	mature B cell differentiation	1.268694e-3
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	1.291935e-3
GO:0007017	microtubule-based process	1.326765e-3
GO:0045582	positive regulation of T cell differentiation	1.355460e-3
GO:0002604	regulation of dendritic cell antigen processing and presentation	1.362384e-3
GO:0046835	carbohydrate phosphorylation	1.381511e-3
GO:0002376	immune system process	1.405893e-3
GO:0030278	regulation of ossification	1.418761e-3
GO:0042493	response to drug	1.436307e-3
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	1.522477e-3
GO:0001817	regulation of cytokine production	1.524725e-3
GO:0045163	clustering of voltage-gated potassium channels	1.566519e-3
GO:0018076	N-terminal peptidyl-lysine acetylation	1.566519e-3
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	1.590416e-3
GO:0006629	lipid metabolic process	1.687104e-3
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	1.743020e-3
GO:0045580	regulation of T cell differentiation	1.763180e-3
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway	1.805664e-3
GO:0019432	triglyceride biosynthetic process	1.858498e-3
GO:0010002	cardioblast differentiation	1.864802e-3
GO:0007259	JAK-STAT cascade	1.886786e-3
GO:0002690	positive regulation of leukocyte chemotaxis	1.888877e-3
GO:0006637	acyl-CoA metabolic process	1.906063e-3
GO:0019693	ribose phosphate metabolic process	1.910765e-3
GO:0070535	histone H2A K63-linked ubiquitination	1.920614e-3
GO:0090107	regulation of high-density lipoprotein particle assembly	1.920614e-3
GO:2000409	positive regulation of T cell extravasation	1.920614e-3
GO:0048239	negative regulation of DNA recombination at telomere	1.920614e-3
GO:0006430	lysyl-tRNA aminoacylation	1.920614e-3
GO:0035696	monocyte extravasation	1.920614e-3
GO:0035705	T-helper 17 cell chemotaxis	1.920614e-3
GO:0043310	negative regulation of eosinophil degranulation	1.920614e-3
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	1.962955e-3
GO:0030514	negative regulation of BMP signaling pathway	2.011081e-3
GO:2000974	negative regulation of pro-B cell differentiation	2.019841e-3
GO:0002687	positive regulation of leukocyte migration	2.044790e-3
GO:0022617	extracellular matrix disassembly	2.046739e-3
GO:0015884	folic acid transport	2.046739e-3
GO:0007409	axonogenesis	2.118325e-3
GO:0032103	positive regulation of response to external stimulus	2.154954e-3
GO:0007157	heterophilic cell-cell adhesion	2.165124e-3
GO:0043420	anthranilate metabolic process	2.168890e-3
GO:0015706	nitrate transport	2.168890e-3
GO:0034516	response to vitamin B6	2.168890e-3
GO:0001959	regulation of cytokine-mediated signaling pathway	2.176893e-3
GO:0051135	positive regulation of NK T cell activation	2.190200e-3
GO:0016579	protein deubiquitination	2.237606e-3
GO:0051963	regulation of synapse assembly	2.243233e-3
GO:0061188	negative regulation of chromatin silencing at rDNA	2.252790e-3
GO:0045113	regulation of integrin biosynthetic process	2.252790e-3
GO:0045603	positive regulation of endothelial cell differentiation	2.272220e-3
GO:0042246	tissue regeneration	2.311843e-3
GO:2000401	regulation of lymphocyte migration	2.360266e-3
GO:0009605	response to external stimulus	2.361100e-3
GO:0019884	antigen processing and presentation of exogenous antigen	2.377212e-3
GO:0040016	embryonic cleavage	2.381769e-3
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	2.393698e-3
GO:0060299	negative regulation of sarcomere organization	2.393698e-3
GO:0048791	calcium ion-dependent exocytosis of neurotransmitter	2.409448e-3
GO:0072109	glomerular mesangium development	2.422674e-3
GO:0033002	muscle cell proliferation	2.440252e-3
GO:0042454	ribonucleoside catabolic process	2.450676e-3
GO:0070228	regulation of lymphocyte apoptosis	2.459079e-3
GO:0043647	inositol phosphate metabolic process	2.495113e-3
GO:0045161	neuronal ion channel clustering	2.530622e-3
GO:0006098	pentose-phosphate shunt	2.631678e-3
GO:0007411	axon guidance	2.641752e-3
GO:0090096	positive regulation of metanephric cap mesenchymal cell proliferation	2.651507e-3
GO:0032964	collagen biosynthetic process	2.683842e-3
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	2.692441e-3
GO:0009972	cytidine deamination	2.696493e-3
GO:0006633	fatty acid biosynthetic process	2.724607e-3
GO:0045124	regulation of bone resorption	2.733008e-3
GO:0002577	regulation of antigen processing and presentation	2.779979e-3
GO:0009132	nucleoside diphosphate metabolic process	2.818034e-3
GO:0045091	regulation of retroviral genome replication	2.855742e-3
GO:0090265	positive regulation of immune complex clearance by monocytes and macrophages	2.881355e-3
GO:0072678	T cell migration	2.881355e-3
GO:0007608	sensory perception of smell	2.912236e-3
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	2.931787e-3
GO:0055089	fatty acid homeostasis	2.947047e-3
GO:0048812	neuron projection morphogenesis	2.951280e-3
GO:0002252	immune effector process	3.006181e-3
GO:0060759	regulation of response to cytokine stimulus	3.130295e-3
GO:0008038	neuron recognition	3.146716e-3
GO:0048631	regulation of skeletal muscle tissue growth	3.196326e-3
GO:0032649	regulation of interferon-gamma production	3.213405e-3
GO:0034605	cellular response to heat	3.235344e-3
GO:0046135	pyrimidine nucleoside catabolic process	3.275012e-3
GO:0045409	negative regulation of interleukin-6 biosynthetic process	3.275012e-3
GO:0002688	regulation of leukocyte chemotaxis	3.311294e-3
GO:0009750	response to fructose stimulus	3.318614e-3
GO:0043353	enucleate erythrocyte differentiation	3.365485e-3
GO:0035329	hippo signaling cascade	3.402215e-3
GO:0006334	nucleosome assembly	3.413649e-3
GO:0030098	lymphocyte differentiation	3.422281e-3
GO:0052509	positive regulation by symbiont of host defense response	3.461284e-3
GO:0052556	positive regulation by symbiont of host immune response	3.461284e-3
GO:0048667	cell morphogenesis involved in neuron differentiation	3.475821e-3
GO:0035587	purinergic receptor signaling pathway	3.502777e-3
GO:0007026	negative regulation of microtubule depolymerization	3.536775e-3
GO:0048666	neuron development	3.598083e-3
GO:0042035	regulation of cytokine biosynthetic process	3.618701e-3
GO:0034103	regulation of tissue remodeling	3.626398e-3
GO:0001818	negative regulation of cytokine production	3.670368e-3
GO:0009164	nucleoside catabolic process	3.674806e-3
GO:0002702	positive regulation of production of molecular mediator of immune response	3.676851e-3
GO:0043134	regulation of hindgut contraction	3.809448e-3
GO:0034767	positive regulation of ion transmembrane transport	3.841179e-3
GO:0014009	glial cell proliferation	3.843919e-3
GO:0007166	cell surface receptor linked signaling pathway	3.844808e-3
GO:0046638	positive regulation of alpha-beta T cell differentiation	3.866861e-3
GO:0001973	adenosine receptor signaling pathway	3.964889e-3
GO:0009133	nucleoside diphosphate biosynthetic process	4.018655e-3
GO:0048247	lymphocyte chemotaxis	4.018655e-3
GO:0048520	positive regulation of behavior	4.133967e-3
GO:0043114	regulation of vascular permeability	4.137738e-3
GO:0031667	response to nutrient levels	4.174047e-3
GO:0090184	positive regulation of kidney development	4.216310e-3
GO:0042536	negative regulation of tumor necrosis factor biosynthetic process	4.232255e-3
GO:0050907	detection of chemical stimulus involved in sensory perception	4.316174e-3
GO:0009265	2'-deoxyribonucleotide biosynthetic process	4.363931e-3
GO:0032101	regulation of response to external stimulus	4.457150e-3
GO:0042908	xenobiotic transport	4.459086e-3
GO:0070814	hydrogen sulfide biosynthetic process	4.488449e-3
GO:0009052	pentose-phosphate shunt, non-oxidative branch	4.491672e-3
GO:0031223	auditory behavior	4.499402e-3
GO:0045659	negative regulation of neutrophil differentiation	4.527729e-3
GO:0010769	regulation of cell morphogenesis involved in differentiation	4.566142e-3
GO:0046850	regulation of bone remodeling	4.598410e-3
GO:0007020	microtubule nucleation	4.605264e-3
GO:0051084	'de novo' posttranslational protein folding	4.649161e-3
GO:0060266	negative regulation of respiratory burst involved in inflammatory response	4.659333e-3
GO:0002579	positive regulation of antigen processing and presentation	4.748802e-3
GO:0045627	positive regulation of T-helper 1 cell differentiation	4.769885e-3
GO:0003093	regulation of glomerular filtration	4.769885e-3
GO:0002830	positive regulation of type 2 immune response	4.769885e-3
GO:0001820	serotonin secretion	4.769885e-3
GO:0006003	fructose 2,6-bisphosphate metabolic process	4.771119e-3
GO:0031069	hair follicle morphogenesis	4.773584e-3
GO:0048546	digestive tract morphogenesis	4.792119e-3
GO:0031023	microtubule organizing center organization	4.818052e-3
GO:0045086	positive regulation of interleukin-2 biosynthetic process	4.874993e-3
GO:0008610	lipid biosynthetic process	4.892634e-3
GO:0051050	positive regulation of transport	4.989173e-3
GO:0045408	regulation of interleukin-6 biosynthetic process	4.994278e-3
GO:0050925	negative regulation of negative chemotaxis	5.044351e-3
GO:0048679	regulation of axon regeneration	5.090802e-3
GO:0007340	acrosome reaction	5.090802e-3
GO:0050708	regulation of protein secretion	5.175863e-3
GO:0032696	negative regulation of interleukin-13 production	5.185746e-3
GO:0030488	tRNA methylation	5.339065e-3
GO:0019882	antigen processing and presentation	5.474792e-3
GO:0045666	positive regulation of neuron differentiation	5.479721e-3
GO:0051928	positive regulation of calcium ion transport	5.654924e-3
GO:0072529	pyrimidine-containing compound catabolic process	5.688355e-3
GO:0031114	regulation of microtubule depolymerization	5.812997e-3
GO:0030316	osteoclast differentiation	5.847687e-3
GO:0045061	thymic T cell selection	5.857400e-3
GO:0045060	negative thymic T cell selection	5.912750e-3
GO:0017156	calcium ion-dependent exocytosis	5.912750e-3
GO:0042632	cholesterol homeostasis	5.970581e-3
GO:0002685	regulation of leukocyte migration	5.970581e-3
GO:0031100	organ regeneration	5.984698e-3
GO:0010820	positive regulation of T cell chemotaxis	6.038760e-3
GO:0072144	glomerular mesangial cell development	6.137813e-3
GO:0006116	NADH oxidation	6.137813e-3
GO:0033133	positive regulation of glucokinase activity	6.137813e-3
GO:0032100	positive regulation of appetite	6.179968e-3
GO:0048144	fibroblast proliferation	6.179968e-3
GO:0006312	mitotic recombination	6.179968e-3
GO:0051660	establishment of centrosome localization	6.215917e-3
GO:0021540	corpus callosum morphogenesis	6.215917e-3
GO:0014743	regulation of muscle hypertrophy	6.240382e-3
GO:0033762	response to glucagon stimulus	6.253659e-3
GO:0006954	inflammatory response	6.313434e-3
GO:0006968	cellular defense response	6.418721e-3
GO:0050770	regulation of axonogenesis	6.439470e-3
GO:0046485	ether lipid metabolic process	6.499107e-3
GO:0055088	lipid homeostasis	6.512671e-3
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein	6.539831e-3
GO:0070208	protein heterotrimerization	6.556880e-3
GO:0046637	regulation of alpha-beta T cell differentiation	6.561963e-3
GO:0003184	pulmonary valve morphogenesis	6.585271e-3
GO:2001021	negative regulation of response to DNA damage stimulus	6.636775e-3
GO:0010569	regulation of double-strand break repair via homologous recombination	6.658029e-3
GO:0030002	cellular anion homeostasis	6.665131e-3
GO:0070646	protein modification by small protein removal	6.685095e-3
GO:0043933	macromolecular complex subunit organization	6.751306e-3
GO:2000406	positive regulation of T cell migration	6.843459e-3
GO:0006014	D-ribose metabolic process	6.991434e-3
GO:0045955	negative regulation of calcium ion-dependent exocytosis	7.137387e-3
GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein	7.137387e-3
GO:0009066	aspartate family amino acid metabolic process	7.149453e-3
GO:0051241	negative regulation of multicellular organismal process	7.174830e-3
GO:0045597	positive regulation of cell differentiation	7.222467e-3
GO:0051262	protein tetramerization	7.248884e-3
GO:0031032	actomyosin structure organization	7.259512e-3
GO:0048858	cell projection morphogenesis	7.405976e-3
GO:0032879	regulation of localization	7.436561e-3
GO:0045494	photoreceptor cell maintenance	7.449382e-3
GO:0017158	regulation of calcium ion-dependent exocytosis	7.504706e-3
GO:0006953	acute-phase response	7.508084e-3
GO:0032845	negative regulation of homeostatic process	7.525742e-3
GO:0046642	negative regulation of alpha-beta T cell proliferation	7.561126e-3
GO:0010935	regulation of macrophage cytokine production	7.676259e-3
GO:0060022	hard palate development	7.734584e-3
GO:0009996	negative regulation of cell fate specification	7.754891e-3
GO:0060251	regulation of glial cell proliferation	7.767064e-3
GO:0019730	antimicrobial humoral response	7.862429e-3
GO:0046496	nicotinamide nucleotide metabolic process	7.933141e-3
GO:0000226	microtubule cytoskeleton organization	8.078436e-3
GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity	8.259062e-3
GO:0050849	negative regulation of calcium-mediated signaling	8.259062e-3
GO:0051081	nuclear envelope disassembly	8.262591e-3
GO:0032732	positive regulation of interleukin-1 production	8.265285e-3
GO:0000097	sulfur amino acid biosynthetic process	8.276956e-3
GO:0002478	antigen processing and presentation of exogenous peptide antigen	8.333728e-3
GO:0070179	D-serine biosynthetic process	8.368521e-3
GO:0031268	pseudopodium organization	8.368521e-3
GO:0009611	response to wounding	8.390470e-3
GO:0043368	positive T cell selection	8.651227e-3
GO:0009067	aspartate family amino acid biosynthetic process	8.653876e-3
GO:0014889	muscle atrophy	8.907249e-3
GO:0002521	leukocyte differentiation	9.001583e-3
GO:0048007	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	9.057235e-3
GO:0046600	negative regulation of centriole replication	9.057235e-3
GO:0043585	nose morphogenesis	9.057235e-3
GO:0006360	transcription from RNA polymerase I promoter	9.241852e-3
GO:0032989	cellular component morphogenesis	9.303911e-3
GO:0032990	cell part morphogenesis	9.313330e-3
GO:0019441	tryptophan catabolic process to kynurenine	9.425152e-3
GO:0009186	deoxyribonucleoside diphosphate metabolic process	9.425152e-3
GO:0048284	organelle fusion	9.479247e-3
GO:0001914	regulation of T cell mediated cytotoxicity	9.479247e-3
GO:0033273	response to vitamin	9.494065e-3
GO:0046718	entry of virus into host cell	9.498115e-3
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	9.543309e-3
GO:0046381	CMP-N-acetylneuraminate metabolic process	9.543309e-3
GO:0071109	superior temporal gyrus development	9.562012e-3
GO:0002752	cell surface pattern recognition receptor signaling pathway	9.562012e-3
GO:0015732	prostaglandin transport	9.562012e-3
GO:2000193	positive regulation of fatty acid transport	9.576003e-3
GO:0035520	monoubiquitinated protein deubiquitination	9.598269e-3
GO:0045616	regulation of keratinocyte differentiation	9.622030e-3
GO:0090279	regulation of calcium ion import	9.690702e-3
GO:0043300	regulation of leukocyte degranulation	9.823477e-3
GO:0042346	positive regulation of NF-kappaB import into nucleus	9.823477e-3
GO:0002903	negative regulation of B cell apoptosis	9.955527e-3
GO:0045920	negative regulation of exocytosis	9.955527e-3
GO:0003018	vascular process in circulatory system	9.958033e-3
GO:0060263	regulation of respiratory burst	1.006711e-2
GO:0031670	cellular response to nutrient	1.017440e-2
GO:0002828	regulation of type 2 immune response	1.029458e-2
GO:0002906	negative regulation of mature B cell apoptosis	1.033664e-2
GO:0043084	penile erection	1.037517e-2
GO:0051494	negative regulation of cytoskeleton organization	1.044090e-2
GO:0035845	photoreceptor cell outer segment organization	1.054129e-2
GO:0045870	positive regulation of retroviral genome replication	1.054129e-2
GO:0033622	integrin activation	1.054129e-2
GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	1.054129e-2
GO:0006666	3-keto-sphinganine metabolic process	1.054129e-2
GO:0015966	diadenosine tetraphosphate biosynthetic process	1.054129e-2
GO:0042490	mechanoreceptor differentiation	1.063274e-2
GO:0048730	epidermis morphogenesis	1.063863e-2
GO:0042941	D-alanine transport	1.073125e-2
GO:0018272	protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine	1.073125e-2
GO:0032109	positive regulation of response to nutrient levels	1.082877e-2
GO:0006784	heme a biosynthetic process	1.082877e-2
GO:0010975	regulation of neuron projection development	1.093501e-2
GO:0050667	homocysteine metabolic process	1.093974e-2
GO:0034198	cellular response to amino acid starvation	1.093974e-2
GO:0046626	regulation of insulin receptor signaling pathway	1.095019e-2
GO:0045980	negative regulation of nucleotide metabolic process	1.097354e-2
GO:0001503	ossification	1.111628e-2
GO:0019321	pentose metabolic process	1.119683e-2
GO:0051046	regulation of secretion	1.121498e-2
GO:0042273	ribosomal large subunit biogenesis	1.124053e-2