Novel motif:129

name:	motif129_CTCGTAATCT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0016072	rRNA metabolic process	2.641869e-9
GO:0046548	retinal rod cell development	7.359870e-9
GO:0009052	pentose-phosphate shunt, non-oxidative branch	9.443651e-9
GO:0051238	sequestering of metal ion	1.910191e-8
GO:0019428	allantoin biosynthetic process	2.043191e-8
GO:0046314	phosphocreatine biosynthetic process	2.197434e-8
GO:0034660	ncRNA metabolic process	2.461196e-8
GO:0022613	ribonucleoprotein complex biogenesis	2.958751e-8
GO:0030321	transepithelial chloride transport	6.071120e-8
GO:0042254	ribosome biogenesis	8.504704e-8
GO:0001696	gastric acid secretion	1.015431e-7
GO:0006098	pentose-phosphate shunt	1.015895e-7
GO:0006364	rRNA processing	1.097808e-7
GO:0045199	maintenance of epithelial cell apical/basal polarity	1.252711e-7
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	1.264456e-7
GO:0006014	D-ribose metabolic process	1.650262e-7
GO:0006880	intracellular sequestering of iron ion	1.676180e-7
GO:0006348	chromatin silencing at telomere	2.096960e-7
GO:0071843	cellular component biogenesis at cellular level	2.229669e-7
GO:0019693	ribose phosphate metabolic process	2.464007e-7
GO:0000959	mitochondrial RNA metabolic process	2.726514e-7
GO:0035425	autocrine signaling	2.734344e-7
GO:0090232	positive regulation of spindle checkpoint	3.147492e-7
GO:0032784	regulation of transcription elongation, DNA-dependent	3.403525e-7
GO:0042396	phosphagen biosynthetic process	3.431374e-7
GO:0006740	NADPH regeneration	3.829471e-7
GO:0090231	regulation of spindle checkpoint	5.110788e-7
GO:0009107	lipoate biosynthetic process	5.170480e-7
GO:0019934	cGMP-mediated signaling	5.396263e-7
GO:0044338	canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation	7.287311e-7
GO:0044339	canonical Wnt receptor signaling pathway involved in osteoblast differentiation	7.287311e-7
GO:0006414	translational elongation	7.928199e-7
GO:0050883	musculoskeletal movement, spinal reflex action	9.141178e-7
GO:0051775	response to redox state	9.902715e-7
GO:0035090	maintenance of apical/basal cell polarity	1.074625e-6
GO:0042632	cholesterol homeostasis	1.136401e-6
GO:0043415	positive regulation of skeletal muscle tissue regeneration	2.230679e-6
GO:0045627	positive regulation of T-helper 1 cell differentiation	2.357736e-6
GO:0000154	rRNA modification	2.811335e-6
GO:0018993	somatic sex determination	2.811335e-6
GO:0006391	transcription initiation from mitochondrial promoter	3.138423e-6
GO:0016071	mRNA metabolic process	3.379860e-6
GO:0045623	negative regulation of T-helper cell differentiation	3.402547e-6
GO:0007199	G-protein signaling, coupled to cGMP nucleotide second messenger	3.437307e-6
GO:0048630	skeletal muscle tissue growth	3.887070e-6
GO:0034470	ncRNA processing	4.089492e-6
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	4.575374e-6
GO:0044330	canonical Wnt receptor signaling pathway involved in positive regulation of wound healing	4.678466e-6
GO:0044328	canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration	4.678466e-6
GO:0044329	canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion	4.678466e-6
GO:0006396	RNA processing	5.130906e-6
GO:0006739	NADP metabolic process	5.294250e-6
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	6.657344e-6
GO:0045724	positive regulation of flagellum assembly	7.025634e-6
GO:0032049	cardiolipin biosynthetic process	7.477710e-6
GO:0019532	oxalate transport	8.011647e-6
GO:0018279	protein N-linked glycosylation via asparagine	8.184290e-6
GO:0055098	response to low-density lipoprotein particle stimulus	8.646804e-6
GO:0045629	negative regulation of T-helper 2 cell differentiation	8.938132e-6
GO:0046636	negative regulation of alpha-beta T cell activation	9.208795e-6
GO:0071850	mitotic cell cycle arrest	9.689147e-6
GO:0034621	cellular macromolecular complex subunit organization	1.036907e-5
GO:0090342	regulation of cell aging	1.102906e-5
GO:0010506	regulation of autophagy	1.195803e-5
GO:0032222	regulation of synaptic transmission, cholinergic	1.333692e-5
GO:0045625	regulation of T-helper 1 cell differentiation	1.375260e-5
GO:0016446	somatic hypermutation of immunoglobulin genes	1.409794e-5
GO:0019321	pentose metabolic process	1.438193e-5
GO:0035105	sterol regulatory element binding protein import into nucleus	1.617656e-5
GO:0010886	positive regulation of cholesterol storage	1.670482e-5
GO:0060084	synaptic transmission involved in micturition	1.855741e-5
GO:0031558	induction of apoptosis in response to chemical stimulus	1.888285e-5
GO:0000733	DNA strand renaturation	1.948976e-5
GO:0008633	activation of pro-apoptotic gene products	2.040222e-5
GO:0071168	protein localization to chromatin	2.150521e-5
GO:0022417	protein maturation by protein folding	2.286362e-5
GO:0009190	cyclic nucleotide biosynthetic process	2.341059e-5
GO:0006486	protein glycosylation	2.382987e-5
GO:0033365	protein localization to organelle	2.413338e-5
GO:0034776	response to histamine	2.490713e-5
GO:0046639	negative regulation of alpha-beta T cell differentiation	2.782326e-5
GO:0040020	regulation of meiosis	2.946760e-5
GO:0051898	negative regulation of protein kinase B signaling cascade	3.029168e-5
GO:0034048	negative regulation of protein phosphatase type 2A activity	3.289365e-5
GO:0070085	glycosylation	3.364569e-5
GO:0060547	negative regulation of necrotic cell death	3.365848e-5
GO:0000183	chromatin silencing at rDNA	3.365848e-5
GO:0006412	translation	3.507812e-5
GO:0060161	positive regulation of dopamine receptor signaling pathway	3.749310e-5
GO:0034109	homotypic cell-cell adhesion	3.797045e-5
GO:0071042	nuclear polyadenylation-dependent mRNA catabolic process	3.812487e-5
GO:2000627	positive regulation of miRNA catabolic process	3.812487e-5
GO:0009106	lipoate metabolic process	3.812487e-5
GO:0000964	mitochondrial RNA 5'-end processing	3.812487e-5
GO:0021895	cerebral cortex neuron differentiation	4.199923e-5
GO:0006390	transcription from mitochondrial promoter	4.253187e-5
GO:0002502	peptide antigen assembly with MHC class I protein complex	4.281206e-5
GO:0006487	protein N-linked glycosylation	4.543404e-5
GO:0000086	G2/M transition of mitotic cell cycle	4.789398e-5
GO:0040040	thermosensory behavior	5.750738e-5
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	5.904557e-5
GO:0045659	negative regulation of neutrophil differentiation	5.904557e-5
GO:0070584	mitochondrion morphogenesis	6.017504e-5
GO:0090234	regulation of kinetochore assembly	6.253625e-5
GO:0090169	regulation of spindle assembly	6.253625e-5
GO:0060026	convergent extension	6.343006e-5
GO:0046717	acid secretion	6.345739e-5
GO:0051445	regulation of meiotic cell cycle	6.471975e-5
GO:0034047	regulation of protein phosphatase type 2A activity	6.777702e-5
GO:0006605	protein targeting	6.918877e-5
GO:0046068	cGMP metabolic process	6.998683e-5
GO:0000422	mitochondrion degradation	7.261647e-5
GO:0044267	cellular protein metabolic process	7.393345e-5
GO:0006733	oxidoreduction coenzyme metabolic process	7.418402e-5
GO:0021853	cerebral cortex GABAergic interneuron migration	7.423531e-5
GO:0071404	cellular response to low-density lipoprotein particle stimulus	7.647628e-5
GO:0042398	cellular modified amino acid biosynthetic process	7.656566e-5
GO:0061014	positive regulation of mRNA catabolic process	7.870672e-5
GO:0006182	cGMP biosynthetic process	8.480122e-5
GO:0032802	low-density lipoprotein particle receptor catabolic process	8.694495e-5
GO:0021764	amygdala development	8.694495e-5
GO:0010939	regulation of necrotic cell death	8.858726e-5
GO:0030574	collagen catabolic process	9.110889e-5
GO:0051329	interphase of mitotic cell cycle	9.269104e-5
GO:0009187	cyclic nucleotide metabolic process	9.311789e-5
GO:0035093	spermatogenesis, exchange of chromosomal proteins	9.640426e-5
GO:0007606	sensory perception of chemical stimulus	9.854407e-5
GO:0007601	visual perception	1.037464e-4
GO:0033091	positive regulation of immature T cell proliferation	1.108292e-4
GO:0071460	cellular response to cell-matrix adhesion	1.145662e-4
GO:0017148	negative regulation of translation	1.147910e-4
GO:0050953	sensory perception of light stimulus	1.181690e-4
GO:0055094	response to lipoprotein stimulus	1.199069e-4
GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis	1.220306e-4
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	1.226397e-4
GO:0034622	cellular macromolecular complex assembly	1.238815e-4
GO:0043933	macromolecular complex subunit organization	1.270451e-4
GO:0009101	glycoprotein biosynthetic process	1.302924e-4
GO:0019362	pyridine nucleotide metabolic process	1.320154e-4
GO:0071402	cellular response to lipoprotein particle stimulus	1.349553e-4
GO:0006139	nucleobase-containing compound metabolic process	1.399251e-4
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	1.444601e-4
GO:0021892	cerebral cortex GABAergic interneuron differentiation	1.444601e-4
GO:0010885	regulation of cholesterol storage	1.488551e-4
GO:0000958	mitochondrial mRNA catabolic process	1.571019e-4
GO:0000965	mitochondrial RNA 3'-end processing	1.571019e-4
GO:0043633	polyadenylation-dependent RNA catabolic process	1.571019e-4
GO:0000962	positive regulation of mitochondrial RNA catabolic process	1.571019e-4
GO:0043687	post-translational protein modification	1.571839e-4
GO:0046483	heterocycle metabolic process	1.574069e-4
GO:0035344	hypoxanthine transport	1.756708e-4
GO:0035364	thymine transport	1.756708e-4
GO:0015854	guanine transport	1.756708e-4
GO:0010836	negative regulation of protein ADP-ribosylation	1.756708e-4
GO:0032224	positive regulation of synaptic transmission, cholinergic	1.831084e-4
GO:0050821	protein stabilization	1.870477e-4
GO:0000028	ribosomal small subunit assembly	1.876156e-4
GO:0050912	detection of chemical stimulus involved in sensory perception of taste	2.059643e-4
GO:0021843	substrate-independent telencephalic tangential interneuron migration	2.086930e-4
GO:0007023	post-chaperonin tubulin folding pathway	2.124939e-4
GO:0010884	positive regulation of lipid storage	2.155670e-4
GO:0008340	determination of adult lifespan	2.186934e-4
GO:0006467	protein thiol-disulfide exchange	2.316999e-4
GO:0018130	heterocycle biosynthetic process	2.317950e-4
GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	2.377339e-4
GO:0014056	regulation of acetylcholine secretion	2.397998e-4
GO:0051155	positive regulation of striated muscle cell differentiation	2.503834e-4
GO:0051591	response to cAMP	2.542789e-4
GO:0055088	lipid homeostasis	2.637272e-4
GO:0070925	organelle assembly	2.644228e-4
GO:0051325	interphase	2.690220e-4
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	2.847400e-4
GO:0001829	trophectodermal cell differentiation	2.975550e-4
GO:0007217	tachykinin receptor signaling pathway	3.018460e-4
GO:0001539	ciliary or flagellar motility	3.129279e-4
GO:0006610	ribosomal protein import into nucleus	3.240513e-4
GO:0042703	menstruation	3.362847e-4
GO:0019101	female somatic sex determination	3.362847e-4
GO:0033554	cellular response to stress	3.390160e-4
GO:0006415	translational termination	3.453224e-4
GO:0030801	positive regulation of cyclic nucleotide metabolic process	3.480498e-4
GO:0042593	glucose homeostasis	3.493873e-4
GO:0071352	cellular response to interleukin-2	3.638266e-4
GO:0031167	rRNA methylation	3.702179e-4
GO:0007131	reciprocal meiotic recombination	3.711877e-4
GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	3.782940e-4
GO:0052565	response to defense-related host nitric oxide production	3.860070e-4
GO:0071826	ribonucleoprotein complex subunit organization	4.087956e-4
GO:0061013	regulation of mRNA catabolic process	4.121548e-4
GO:0055086	nucleobase-containing small molecule metabolic process	4.185513e-4
GO:0006463	steroid hormone receptor complex assembly	4.214982e-4
GO:0019083	viral transcription	4.223282e-4
GO:0051856	adhesion to symbiont	4.228499e-4
GO:0002825	regulation of T-helper 1 type immune response	4.295620e-4
GO:0006914	autophagy	4.345594e-4
GO:0051186	cofactor metabolic process	4.352603e-4
GO:0060479	lung cell differentiation	4.355229e-4
GO:0031557	induction of programmed cell death in response to chemical stimulus	4.452201e-4
GO:0008272	sulfate transport	4.452201e-4
GO:0060306	regulation of membrane repolarization	4.642243e-4
GO:0046709	IDP catabolic process	4.642243e-4
GO:0046032	ADP catabolic process	4.642243e-4
GO:0045656	negative regulation of monocyte differentiation	4.763215e-4
GO:0032416	negative regulation of sodium:hydrogen antiporter activity	4.763215e-4
GO:0032933	SREBP-mediated signaling pathway	4.801248e-4
GO:0001510	RNA methylation	4.823165e-4
GO:0002016	regulation of blood volume by renin-angiotensin	4.891144e-4
GO:0031547	brain-derived neurotrophic factor receptor signaling pathway	5.027429e-4
GO:0032886	regulation of microtubule-based process	5.047661e-4
GO:0035556	intracellular signal transduction	5.216904e-4
GO:0042255	ribosome assembly	5.350566e-4
GO:0006401	RNA catabolic process	5.380958e-4
GO:0048821	erythrocyte development	5.685376e-4
GO:0071028	nuclear mRNA surveillance	5.816547e-4
GO:0010835	regulation of protein ADP-ribosylation	5.816547e-4
GO:0051188	cofactor biosynthetic process	6.000593e-4
GO:0000966	RNA 5'-end processing	6.101143e-4
GO:0001574	ganglioside biosynthetic process	6.147958e-4
GO:0002074	extraocular skeletal muscle development	6.271853e-4
GO:0045622	regulation of T-helper cell differentiation	6.298846e-4
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	6.396382e-4
GO:0016575	histone deacetylation	6.436724e-4
GO:0022618	ribonucleoprotein complex assembly	6.567553e-4
GO:0060299	negative regulation of sarcomere organization	6.639929e-4
GO:0033292	T-tubule organization	6.639929e-4
GO:0035522	monoubiquitinated histone H2A deubiquitination	6.639929e-4
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	6.941370e-4
GO:0034633	retinol transport	7.035291e-4
GO:0090230	regulation of centromere complex assembly	7.058592e-4
GO:0090224	regulation of spindle organization	7.138082e-4
GO:0048213	Golgi vesicle prefusion complex stabilization	7.138138e-4
GO:0031118	rRNA pseudouridine synthesis	7.138138e-4
GO:0060487	lung epithelial cell differentiation	7.308121e-4
GO:0006688	glycosphingolipid biosynthetic process	7.614052e-4
GO:0035815	positive regulation of renal sodium excretion	7.675101e-4
GO:0021533	cell differentiation in hindbrain	7.889228e-4
GO:0006891	intra-Golgi vesicle-mediated transport	7.955848e-4
GO:0009123	nucleoside monophosphate metabolic process	8.102771e-4
GO:0030521	androgen receptor signaling pathway	8.264075e-4
GO:0048659	smooth muscle cell proliferation	8.312796e-4
GO:0031104	dendrite regeneration	8.435168e-4
GO:0050907	detection of chemical stimulus involved in sensory perception	8.450039e-4
GO:0006868	glutamine transport	8.548397e-4
GO:0034337	RNA folding	8.548397e-4
GO:0072521	purine-containing compound metabolic process	8.967595e-4
GO:0032922	circadian regulation of gene expression	9.021115e-4
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	9.252430e-4
GO:0000278	mitotic cell cycle	9.691602e-4
GO:0071321	cellular response to cGMP	9.694364e-4
GO:0060044	negative regulation of cardiac muscle cell proliferation	9.694364e-4
GO:0046031	ADP metabolic process	9.694364e-4
GO:0015696	ammonium transport	9.756049e-4
GO:0006298	mismatch repair	1.005138e-3
GO:0090343	positive regulation of cell aging	1.006514e-3
GO:0009185	ribonucleoside diphosphate metabolic process	1.034923e-3
GO:0035094	response to nicotine	1.056018e-3
GO:0007254	JNK cascade	1.063156e-3
GO:0032780	negative regulation of ATPase activity	1.073823e-3
GO:0051937	catecholamine transport	1.078281e-3
GO:0031647	regulation of protein stability	1.113790e-3
GO:0048291	isotype switching to IgG isotypes	1.118174e-3
GO:0002368	B cell cytokine production	1.118174e-3
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	1.118174e-3
GO:0042462	eye photoreceptor cell development	1.131495e-3
GO:0006289	nucleotide-excision repair	1.159310e-3
GO:0034454	microtubule anchoring at centrosome	1.184337e-3
GO:0070305	response to cGMP	1.196493e-3
GO:0034504	protein localization to nucleus	1.225641e-3
GO:0071257	cellular response to electrical stimulus	1.228175e-3
GO:0043604	amide biosynthetic process	1.241738e-3
GO:0022900	electron transport chain	1.257118e-3
GO:0006458	'de novo' protein folding	1.291251e-3
GO:2000279	negative regulation of DNA biosynthetic process	1.320726e-3
GO:0009191	ribonucleoside diphosphate catabolic process	1.339249e-3
GO:0019087	transformation of host cell by virus	1.370642e-3
GO:0030825	positive regulation of cGMP metabolic process	1.384837e-3
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	1.420127e-3
GO:0045010	actin nucleation	1.449680e-3
GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis	1.449680e-3
GO:0042273	ribosomal large subunit biogenesis	1.465137e-3
GO:0021697	cerebellar cortex formation	1.468388e-3
GO:0007608	sensory perception of smell	1.530952e-3
GO:0030850	prostate gland development	1.555550e-3
GO:0046907	intracellular transport	1.566139e-3
GO:0030186	melatonin metabolic process	1.598318e-3
GO:0009124	nucleoside monophosphate biosynthetic process	1.603191e-3
GO:0044262	cellular carbohydrate metabolic process	1.616731e-3
GO:0001920	negative regulation of receptor recycling	1.642173e-3
GO:0060073	micturition	1.679013e-3
GO:0072600	establishment of protein localization in Golgi	1.701247e-3
GO:0042461	photoreceptor cell development	1.750292e-3
GO:0031098	stress-activated protein kinase signaling cascade	1.795018e-3
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	1.800229e-3
GO:0006767	water-soluble vitamin metabolic process	1.840773e-3
GO:0070972	protein localization in endoplasmic reticulum	1.867271e-3
GO:0002541	activation of plasma proteins involved in acute inflammatory response	1.872998e-3
GO:0051929	positive regulation of calcium ion transport via voltage-gated calcium channel activity	1.885833e-3
GO:0071320	cellular response to cAMP	1.912567e-3
GO:0009117	nucleotide metabolic process	1.914419e-3
GO:0048843	negative regulation of axon extension involved in axon guidance	1.938243e-3
GO:0009593	detection of chemical stimulus	1.946789e-3
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	1.952466e-3
GO:0015920	lipopolysaccharide transport	1.967772e-3
GO:0060685	regulation of prostatic bud formation	1.973383e-3
GO:0044029	hypomethylation of CpG island	2.019943e-3
GO:0042699	follicle-stimulating hormone signaling pathway	2.019943e-3
GO:0044260	cellular macromolecule metabolic process	2.034858e-3
GO:0071407	cellular response to organic cyclic compound	2.110651e-3
GO:0070633	transepithelial transport	2.116574e-3
GO:0045956	positive regulation of calcium ion-dependent exocytosis	2.119571e-3
GO:0071025	RNA surveillance	2.156807e-3
GO:0000042	protein targeting to Golgi	2.160101e-3
GO:0009311	oligosaccharide metabolic process	2.232341e-3
GO:0016070	RNA metabolic process	2.254049e-3
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	2.284811e-3
GO:0045333	cellular respiration	2.294964e-3
GO:0043048	dolichyl monophosphate biosynthetic process	2.296956e-3
GO:0061003	positive regulation of dendritic spine morphogenesis	2.314780e-3
GO:0071526	semaphorin-plexin signaling pathway	2.341805e-3
GO:0007168	receptor guanylyl cyclase signaling pathway	2.427191e-3
GO:0042775	mitochondrial ATP synthesis coupled electron transport	2.463526e-3
GO:0045981	positive regulation of nucleotide metabolic process	2.470544e-3
GO:0006422	aspartyl-tRNA aminoacylation	2.470690e-3
GO:0031133	regulation of axon diameter	2.527459e-3
GO:0016926	protein desumoylation	2.527459e-3
GO:0030952	establishment or maintenance of cytoskeleton polarity	2.543262e-3
GO:0060520	activation of prostate induction by androgen receptor signaling pathway	2.544857e-3
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	2.544857e-3
GO:0048313	Golgi inheritance	2.544857e-3
GO:0045720	negative regulation of integrin biosynthetic process	2.544857e-3
GO:0019102	male somatic sex determination	2.544857e-3
GO:0090205	positive regulation of cholesterol metabolic process	2.576594e-3
GO:0034067	protein localization in Golgi apparatus	2.599582e-3
GO:0006732	coenzyme metabolic process	2.605498e-3
GO:0061136	regulation of proteasomal protein catabolic process	2.609706e-3
GO:0006119	oxidative phosphorylation	2.610001e-3
GO:0007030	Golgi organization	2.668669e-3
GO:0050873	brown fat cell differentiation	2.671295e-3
GO:0006402	mRNA catabolic process	2.673931e-3
GO:0007265	Ras protein signal transduction	2.700594e-3
GO:0030237	female sex determination	2.711594e-3
GO:0046365	monosaccharide catabolic process	2.717142e-3
GO:0006397	mRNA processing	2.722298e-3
GO:0030011	maintenance of cell polarity	2.729306e-3
GO:0046605	regulation of centrosome cycle	2.740918e-3
GO:0007091	mitotic metaphase/anaphase transition	2.740918e-3
GO:0045116	protein neddylation	2.754835e-3
GO:0000301	retrograde transport, vesicle recycling within Golgi	2.784197e-3
GO:0001881	receptor recycling	2.816432e-3
GO:0022904	respiratory electron transport chain	2.833641e-3
GO:0030804	positive regulation of cyclic nucleotide biosynthetic process	2.872281e-3
GO:0090303	positive regulation of wound healing	2.906251e-3
GO:0032274	gonadotropin secretion	2.906251e-3
GO:0030330	DNA damage response, signal transduction by p53 class mediator	2.973451e-3
GO:0008152	metabolic process	2.982680e-3
GO:0070508	cholesterol import	2.997563e-3
GO:0045658	regulation of neutrophil differentiation	3.001004e-3
GO:0060159	regulation of dopamine receptor signaling pathway	3.009945e-3
GO:0010921	regulation of phosphatase activity	3.063962e-3
GO:0000460	maturation of 5.8S rRNA	3.069419e-3
GO:0060286	flagellar cell motility	3.092438e-3
GO:0090304	nucleic acid metabolic process	3.094624e-3
GO:0001702	gastrulation with mouth forming second	3.136867e-3
GO:0060736	prostate gland growth	3.194853e-3
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	3.249410e-3
GO:0048143	astrocyte activation	3.256303e-3
GO:0045986	negative regulation of smooth muscle contraction	3.256303e-3
GO:0046164	alcohol catabolic process	3.307912e-3
GO:0060157	urinary bladder development	3.313498e-3
GO:0005975	carbohydrate metabolic process	3.336367e-3
GO:0060412	ventricular septum morphogenesis	3.370414e-3
GO:0050922	negative regulation of chemotaxis	3.378265e-3
GO:0048148	behavioral response to cocaine	3.399316e-3
GO:0032230	positive regulation of synaptic transmission, GABAergic	3.431818e-3
GO:0009179	purine ribonucleoside diphosphate metabolic process	3.437689e-3
GO:0043241	protein complex disassembly	3.534528e-3
GO:0048743	positive regulation of skeletal muscle fiber development	3.604273e-3
GO:0031115	negative regulation of microtubule polymerization	3.604273e-3
GO:0051299	centrosome separation	3.610643e-3
GO:0019511	peptidyl-proline hydroxylation	3.634522e-3
GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase	3.644639e-3
GO:0032415	regulation of sodium:hydrogen antiporter activity	3.648199e-3
GO:0016082	synaptic vesicle priming	3.648199e-3
GO:0007600	sensory perception	3.718378e-3
GO:0015844	monoamine transport	3.721442e-3
GO:0060134	prepulse inhibition	3.739233e-3
GO:0045351	type I interferon biosynthetic process	3.824512e-3
GO:0030238	male sex determination	3.858144e-3
GO:0006007	glucose catabolic process	3.859520e-3
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	3.903426e-3
GO:0033083	regulation of immature T cell proliferation	3.994697e-3
GO:0006600	creatine metabolic process	3.994697e-3
GO:0034641	cellular nitrogen compound metabolic process	4.031272e-3
GO:0035621	ER to Golgi ceramide transport	4.037376e-3
GO:0010477	response to sulfur dioxide	4.037376e-3
GO:0002457	T cell antigen processing and presentation	4.037376e-3
GO:0070673	response to interleukin-18	4.062682e-3
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.062682e-3
GO:0051531	NFAT protein import into nucleus	4.062682e-3
GO:0045910	negative regulation of DNA recombination	4.080905e-3
GO:0010467	gene expression	4.137112e-3
GO:0009108	coenzyme biosynthetic process	4.151915e-3
GO:0007190	activation of adenylate cyclase activity	4.158305e-3
GO:0030901	midbrain development	4.198452e-3
GO:0051588	regulation of neurotransmitter transport	4.204952e-3
GO:0090274	positive regulation of somatostatin secretion	4.225630e-3
GO:0006606	protein import into nucleus	4.333466e-3
GO:0001556	oocyte maturation	4.484051e-3
GO:0035567	non-canonical Wnt receptor signaling pathway	4.486705e-3
GO:0065003	macromolecular complex assembly	4.535428e-3
GO:0044237	cellular metabolic process	4.545350e-3
GO:0016119	carotene metabolic process	4.565077e-3
GO:0001731	formation of translation preinitiation complex	4.565077e-3
GO:0060056	mammary gland involution	4.652773e-3
GO:0019320	hexose catabolic process	4.726517e-3
GO:0051549	positive regulation of keratinocyte migration	4.756484e-3
GO:0043624	cellular protein complex disassembly	4.759607e-3
GO:0045581	negative regulation of T cell differentiation	4.768022e-3
GO:0009181	purine ribonucleoside diphosphate catabolic process	4.805614e-3
GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development	4.813895e-3
GO:0035092	sperm chromatin condensation	4.813895e-3
GO:0001754	eye photoreceptor cell differentiation	4.859743e-3
GO:0006476	protein deacetylation	4.877061e-3
GO:0006352	transcription initiation, DNA-dependent	4.915741e-3
GO:0090181	regulation of cholesterol metabolic process	5.006239e-3
GO:0006281	DNA repair	5.066234e-3
GO:0032727	positive regulation of interferon-alpha production	5.082904e-3
GO:0010721	negative regulation of cell development	5.119813e-3
GO:0031018	endocrine pancreas development	5.157175e-3
GO:0031117	positive regulation of microtubule depolymerization	5.245395e-3
GO:0007033	vacuole organization	5.264186e-3
GO:0006464	protein modification process	5.275436e-3
GO:0034381	plasma lipoprotein particle clearance	5.384008e-3
GO:0061153	trachea gland development	5.416314e-3
GO:0043412	macromolecule modification	5.520559e-3
GO:0097006	regulation of plasma lipoprotein particle levels	5.546467e-3
GO:0045762	positive regulation of adenylate cyclase activity	5.673148e-3
GO:0045047	protein targeting to ER	5.675715e-3
GO:0034728	nucleosome organization	5.685814e-3
GO:0046496	nicotinamide nucleotide metabolic process	5.700305e-3
GO:0051208	sequestering of calcium ion	5.713922e-3
GO:0035601	protein deacylation	5.752439e-3
GO:0071560	cellular response to transforming growth factor beta stimulus	5.821774e-3
GO:0070528	protein kinase C signaling cascade	5.836216e-3
GO:0035019	somatic stem cell maintenance	5.944727e-3
GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation	5.984441e-3
GO:0035928	rRNA import into mitochondrion	5.984441e-3
GO:0042770	signal transduction in response to DNA damage	6.061236e-3
GO:0070507	regulation of microtubule cytoskeleton organization	6.078814e-3
GO:0044271	cellular nitrogen compound biosynthetic process	6.083912e-3
GO:0019805	quinolinate biosynthetic process	6.133848e-3
GO:0006825	copper ion transport	6.196134e-3
GO:0051170	nuclear import	6.295520e-3
GO:0048854	brain morphogenesis	6.358883e-3
GO:0006622	protein targeting to lysosome	6.393582e-3
GO:0006821	chloride transport	6.398336e-3
GO:0033092	positive regulation of immature T cell proliferation in thymus	6.418161e-3
GO:0035095	behavioral response to nicotine	6.418161e-3
GO:0001825	blastocyst formation	6.433803e-3
GO:0060428	lung epithelium development	6.468930e-3
GO:0000045	autophagic vacuole assembly	6.497246e-3
GO:0060168	positive regulation of adenosine receptor signaling pathway	6.528525e-3
GO:0071206	establishment of protein localization to juxtaparanode region of axon	6.528525e-3
GO:0051053	negative regulation of DNA metabolic process	6.585675e-3
GO:0033148	positive regulation of estrogen receptor signaling pathway	6.615725e-3
GO:0046530	photoreceptor cell differentiation	6.705998e-3
GO:0045540	regulation of cholesterol biosynthetic process	6.744105e-3
GO:0043603	cellular amide metabolic process	6.762911e-3
GO:0031345	negative regulation of cell projection organization	6.805942e-3
GO:0044243	multicellular organismal catabolic process	6.811186e-3
GO:0061350	planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	6.874828e-3
GO:0061354	planar cell polarity pathway involved in pericardium morphogenesis	6.874828e-3
GO:0061349	planar cell polarity pathway involved in cardiac right atrium morphogenesis	6.874828e-3
GO:0061347	planar cell polarity pathway involved in outflow tract morphogenesis	6.874828e-3
GO:0032536	regulation of cell projection size	6.874828e-3
GO:0060210	metestrus	6.874828e-3
GO:0061348	planar cell polarity pathway involved in ventricular septum morphogenesis	6.874828e-3
GO:0034502	protein localization to chromosome	6.953590e-3
GO:2000678	negative regulation of transcription regulatory region DNA binding	6.977874e-3
GO:0032984	macromolecular complex disassembly	7.175561e-3
GO:0030091	protein repair	7.302489e-3
GO:0090288	negative regulation of cellular response to growth factor stimulus	7.444069e-3
GO:0070914	UV-damage excision repair	7.449406e-3
GO:0070669	response to interleukin-2	7.654525e-3
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	7.654525e-3
GO:0002543	activation of blood coagulation via clotting cascade	7.654525e-3
GO:0060338	regulation of type I interferon-mediated signaling pathway	7.664497e-3
GO:0048610	cellular process involved in reproduction	7.700907e-3
GO:0031281	positive regulation of cyclase activity	7.744167e-3
GO:0060020	Bergmann glial cell differentiation	7.747475e-3
GO:0046620	regulation of organ growth	7.788719e-3
GO:0043044	ATP-dependent chromatin remodeling	7.807154e-3
GO:0061049	cell growth involved in cardiac muscle cell development	7.840609e-3
GO:0014873	response to muscle activity involved in regulation of muscle adaptation	7.840609e-3
GO:0003331	positive regulation of extracellular matrix constituent secretion	7.840609e-3
GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure	7.840609e-3
GO:0051095	regulation of helicase activity	7.859830e-3
GO:0001550	ovarian cumulus expansion	7.859830e-3
GO:0000255	allantoin metabolic process	7.859830e-3
GO:0006807	nitrogen compound metabolic process	7.868940e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0006540	glutamate decarboxylation to succinate	4.259772e-15
GO:0035520	monoubiquitinated protein deubiquitination	2.540633e-12
GO:0006538	glutamate catabolic process	2.517289e-11
GO:0032870	cellular response to hormone stimulus	4.012767e-10
GO:0042136	neurotransmitter biosynthetic process	6.756864e-9
GO:0009065	glutamine family amino acid catabolic process	7.650831e-9
GO:0006536	glutamate metabolic process	9.004326e-9
GO:0009755	hormone-mediated signaling pathway	1.712467e-8
GO:0006105	succinate metabolic process	3.578182e-8
GO:0071495	cellular response to endogenous stimulus	3.896613e-8
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	4.626001e-8
GO:0009719	response to endogenous stimulus	5.631417e-8
GO:0071872	cellular response to epinephrine stimulus	6.164295e-8
GO:0006702	androgen biosynthetic process	1.106855e-7
GO:0050685	positive regulation of mRNA processing	1.107204e-7
GO:0048545	response to steroid hormone stimulus	1.227877e-7
GO:0002118	aggressive behavior	1.273740e-7
GO:0009725	response to hormone stimulus	1.520881e-7
GO:0043627	response to estrogen stimulus	2.156619e-7
GO:0009064	glutamine family amino acid metabolic process	2.623462e-7
GO:0032355	response to estradiol stimulus	3.322853e-7
GO:0007258	JUN phosphorylation	3.821791e-7
GO:0071394	cellular response to testosterone stimulus	4.226652e-7
GO:0006780	uroporphyrinogen III biosynthetic process	4.406008e-7
GO:0006940	regulation of smooth muscle contraction	4.681746e-7
GO:0042104	positive regulation of activated T cell proliferation	5.406440e-7
GO:0042747	circadian sleep/wake cycle, REM sleep	6.068484e-7
GO:0033152	immunoglobulin V(D)J recombination	6.866828e-7
GO:0043154	negative regulation of caspase activity	1.363551e-6
GO:0045622	regulation of T-helper cell differentiation	1.767415e-6
GO:0021764	amygdala development	1.903663e-6
GO:0031117	positive regulation of microtubule depolymerization	1.957081e-6
GO:0071383	cellular response to steroid hormone stimulus	1.995302e-6
GO:0015701	bicarbonate transport	2.365519e-6
GO:0070925	organelle assembly	2.418581e-6
GO:0050870	positive regulation of T cell activation	2.876228e-6
GO:0006165	nucleoside diphosphate phosphorylation	3.183998e-6
GO:0006228	UTP biosynthetic process	3.183998e-6
GO:0046006	regulation of activated T cell proliferation	3.202764e-6
GO:2000725	regulation of cardiac muscle cell differentiation	3.499792e-6
GO:0060010	Sertoli cell fate commitment	3.708462e-6
GO:0048026	positive regulation of nuclear mRNA splicing, via spliceosome	4.115967e-6
GO:0006183	GTP biosynthetic process	4.244143e-6
GO:0046939	nucleotide phosphorylation	4.798152e-6
GO:0060056	mammary gland involution	5.489173e-6
GO:0006241	CTP biosynthetic process	6.403978e-6
GO:0071391	cellular response to estrogen stimulus	7.525774e-6
GO:0043401	steroid hormone mediated signaling pathway	7.581157e-6
GO:0048630	skeletal muscle tissue growth	8.322560e-6
GO:0030522	intracellular receptor mediated signaling pathway	9.458806e-6
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	9.639420e-6
GO:0010983	positive regulation of high-density lipoprotein particle clearance	1.139767e-5
GO:0071346	cellular response to interferon-gamma	1.176943e-5
GO:0072268	pattern specification involved in metanephros development	1.203308e-5
GO:0008045	motor axon guidance	1.518210e-5
GO:0031115	negative regulation of microtubule polymerization	1.595125e-5
GO:0021542	dentate gyrus development	1.646151e-5
GO:0021571	rhombomere 5 development	1.815480e-5
GO:0002639	positive regulation of immunoglobulin production	1.837188e-5
GO:0042102	positive regulation of T cell proliferation	1.865000e-5
GO:0035093	spermatogenesis, exchange of chromosomal proteins	1.871543e-5
GO:0051384	response to glucocorticoid stimulus	1.897122e-5
GO:0051904	pigment granule transport	2.373424e-5
GO:0001893	maternal placenta development	2.403089e-5
GO:0051905	establishment of pigment granule localization	2.436243e-5
GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	2.436243e-5
GO:0000045	autophagic vacuole assembly	2.695957e-5
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	3.002155e-5
GO:0001539	ciliary or flagellar motility	3.281942e-5
GO:0009267	cellular response to starvation	3.359401e-5
GO:0046628	positive regulation of insulin receptor signaling pathway	3.489195e-5
GO:0010893	positive regulation of steroid biosynthetic process	3.786181e-5
GO:0034259	negative regulation of Rho GTPase activity	3.946144e-5
GO:0010986	positive regulation of lipoprotein particle clearance	3.946144e-5
GO:2000727	positive regulation of cardiac muscle cell differentiation	4.009308e-5
GO:0046502	uroporphyrinogen III metabolic process	4.055742e-5
GO:0019229	regulation of vasoconstriction	4.120227e-5
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	4.283804e-5
GO:0045630	positive regulation of T-helper 2 cell differentiation	4.527872e-5
GO:0045956	positive regulation of calcium ion-dependent exocytosis	4.732390e-5
GO:0043434	response to peptide hormone stimulus	5.476972e-5
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	5.953490e-5
GO:0051251	positive regulation of lymphocyte activation	6.009581e-5
GO:0002329	pre-B cell differentiation	6.236623e-5
GO:0035284	brain segmentation	6.280862e-5
GO:2000467	positive regulation of glycogen (starch) synthase activity	6.402434e-5
GO:0045628	regulation of T-helper 2 cell differentiation	6.702436e-5
GO:0051346	negative regulation of hydrolase activity	6.763246e-5
GO:0010466	negative regulation of peptidase activity	7.282082e-5
GO:0070295	renal water absorption	7.345308e-5
GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis	7.470892e-5
GO:0006703	estrogen biosynthetic process	7.668211e-5
GO:0006833	water transport	7.745406e-5
GO:2000273	positive regulation of receptor activity	8.003301e-5
GO:0008033	tRNA processing	8.206576e-5
GO:0051443	positive regulation of ubiquitin-protein ligase activity	8.230695e-5
GO:0032736	positive regulation of interleukin-13 production	8.527253e-5
GO:0002377	immunoglobulin production	8.685874e-5
GO:0051013	microtubule severing	8.853001e-5
GO:0008347	glial cell migration	8.996383e-5
GO:0016236	macroautophagy	9.552883e-5
GO:0042493	response to drug	9.651109e-5
GO:0018230	peptidyl-L-cysteine S-palmitoylation	9.940288e-5
GO:0014912	negative regulation of smooth muscle cell migration	1.006793e-4
GO:0009147	pyrimidine nucleoside triphosphate metabolic process	1.077108e-4
GO:0060591	chondroblast differentiation	1.145194e-4
GO:0071310	cellular response to organic substance	1.207637e-4
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	1.224903e-4
GO:0021666	rhombomere 5 formation	1.230106e-4
GO:0021660	rhombomere 3 formation	1.230106e-4
GO:0050867	positive regulation of cell activation	1.247196e-4
GO:0021819	layer formation in cerebral cortex	1.317517e-4
GO:0050671	positive regulation of lymphocyte proliferation	1.357610e-4
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	1.373953e-4
GO:0045221	negative regulation of FasL biosynthetic process	1.373953e-4
GO:0002731	negative regulation of dendritic cell cytokine production	1.373953e-4
GO:0003097	renal water transport	1.510277e-4
GO:0071375	cellular response to peptide hormone stimulus	1.556940e-4
GO:0032946	positive regulation of mononuclear cell proliferation	1.596994e-4
GO:0046697	decidualization	1.608251e-4
GO:0051591	response to cAMP	1.659018e-4
GO:0048278	vesicle docking	1.691875e-4
GO:0045787	positive regulation of cell cycle	1.722508e-4
GO:0070665	positive regulation of leukocyte proliferation	1.809013e-4
GO:0021960	anterior commissure morphogenesis	1.877167e-4
GO:0002440	production of molecular mediator of immune response	2.020264e-4
GO:0033120	positive regulation of RNA splicing	2.057513e-4
GO:0031960	response to corticosteroid stimulus	2.168972e-4
GO:0042044	fluid transport	2.202064e-4
GO:0050684	regulation of mRNA processing	2.433988e-4
GO:0061037	negative regulation of cartilage development	2.461542e-4
GO:0051875	pigment granule localization	2.472746e-4
GO:0050891	multicellular organismal water homeostasis	2.472746e-4
GO:0090031	positive regulation of steroid hormone biosynthetic process	2.537074e-4
GO:2000465	regulation of glycogen (starch) synthase activity	2.638745e-4
GO:0030488	tRNA methylation	2.686963e-4
GO:0002696	positive regulation of leukocyte activation	2.716279e-4
GO:0051351	positive regulation of ligase activity	2.783565e-4
GO:0022407	regulation of cell-cell adhesion	2.806371e-4
GO:0032272	negative regulation of protein polymerization	2.839827e-4
GO:0008636	activation of caspase activity by protein phosphorylation	2.844442e-4
GO:0035409	histone H3-Y41 phosphorylation	2.844442e-4
GO:0043648	dicarboxylic acid metabolic process	2.944700e-4
GO:0045768	positive regulation of anti-apoptosis	3.190926e-4
GO:0072086	specification of loop of Henle identity	3.201568e-4
GO:0042448	progesterone metabolic process	3.204782e-4
GO:0042594	response to starvation	3.320817e-4
GO:0008209	androgen metabolic process	3.370717e-4
GO:0046889	positive regulation of lipid biosynthetic process	3.545330e-4
GO:0032754	positive regulation of interleukin-5 production	3.577215e-4
GO:0007260	tyrosine phosphorylation of STAT protein	3.592139e-4
GO:0031017	exocrine pancreas development	3.592587e-4
GO:0016081	synaptic vesicle docking involved in exocytosis	3.595151e-4
GO:0042446	hormone biosynthetic process	3.820311e-4
GO:0042699	follicle-stimulating hormone signaling pathway	3.831393e-4
GO:0045078	positive regulation of interferon-gamma biosynthetic process	3.932773e-4
GO:0035092	sperm chromatin condensation	4.396560e-4
GO:0018108	peptidyl-tyrosine phosphorylation	4.401464e-4
GO:0007033	vacuole organization	4.401464e-4
GO:0035750	protein localization to myelin sheath abaxonal region	4.636185e-4
GO:0035105	sterol regulatory element binding protein import into nucleus	4.636185e-4
GO:0003091	renal water homeostasis	4.730113e-4
GO:0042113	B cell activation	4.850070e-4
GO:0006913	nucleocytoplasmic transport	4.912284e-4
GO:0060992	response to fungicide	5.139432e-4
GO:0048384	retinoic acid receptor signaling pathway	5.241060e-4
GO:0052548	regulation of endopeptidase activity	5.328912e-4
GO:0045725	positive regulation of glycogen biosynthetic process	5.535563e-4
GO:0045840	positive regulation of mitosis	5.766813e-4
GO:0006694	steroid biosynthetic process	6.156802e-4
GO:0071870	cellular response to catecholamine stimulus	6.167175e-4
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	6.528038e-4
GO:0051169	nuclear transport	6.844411e-4
GO:0046637	regulation of alpha-beta T cell differentiation	7.134985e-4
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	7.186822e-4
GO:0015705	iodide transport	7.186822e-4
GO:0044140	negative regulation of growth of symbiont on or near host surface	7.283768e-4
GO:2000178	negative regulation of neural precursor cell proliferation	7.323804e-4
GO:0070293	renal absorption	7.515986e-4
GO:0071577	zinc ion transmembrane transport	7.787016e-4
GO:0003084	positive regulation of systemic arterial blood pressure	8.093225e-4
GO:0014037	Schwann cell differentiation	8.220002e-4
GO:0016082	synaptic vesicle priming	8.262524e-4
GO:0030321	transepithelial chloride transport	8.262524e-4
GO:0032780	negative regulation of ATPase activity	8.398653e-4
GO:0046886	positive regulation of hormone biosynthetic process	8.632625e-4
GO:0070875	positive regulation of glycogen metabolic process	9.053726e-4
GO:0072081	specification of nephron tubule identity	9.104300e-4
GO:0042359	vitamin D metabolic process	9.278867e-4
GO:0021658	rhombomere 3 morphogenesis	9.756320e-4
GO:0032370	positive regulation of lipid transport	9.801057e-4
GO:0021954	central nervous system neuron development	1.045975e-3
GO:0006505	GPI anchor metabolic process	1.046153e-3
GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions	1.072835e-3
GO:0032354	response to follicle-stimulating hormone stimulus	1.084455e-3
GO:0010631	epithelial cell migration	1.090897e-3
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.094567e-3
GO:0071320	cellular response to cAMP	1.113018e-3
GO:0017148	negative regulation of translation	1.149638e-3
GO:0035815	positive regulation of renal sodium excretion	1.159751e-3
GO:0051897	positive regulation of protein kinase B signaling cascade	1.163889e-3
GO:0051970	negative regulation of transmission of nerve impulse	1.179979e-3
GO:2000116	regulation of cysteine-type endopeptidase activity	1.190298e-3
GO:0032401	establishment of melanosome localization	1.196964e-3
GO:0071549	cellular response to dexamethasone stimulus	1.197859e-3
GO:0031113	regulation of microtubule polymerization	1.218704e-3
GO:0060399	positive regulation of growth hormone receptor signaling pathway	1.225773e-3
GO:0031112	positive regulation of microtubule polymerization or depolymerization	1.255427e-3
GO:0061014	positive regulation of mRNA catabolic process	1.269572e-3
GO:0060008	Sertoli cell differentiation	1.269991e-3
GO:0043486	histone exchange	1.291114e-3
GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly	1.295151e-3
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	1.302842e-3
GO:0043242	negative regulation of protein complex disassembly	1.302912e-3
GO:0031667	response to nutrient levels	1.308584e-3
GO:0046677	response to antibiotic	1.315329e-3
GO:0010389	regulation of G2/M transition of mitotic cell cycle	1.324580e-3
GO:0000381	regulation of alternative nuclear mRNA splicing, via spliceosome	1.324580e-3
GO:0042993	positive regulation of transcription factor import into nucleus	1.363359e-3
GO:0045072	regulation of interferon-gamma biosynthetic process	1.367237e-3
GO:0006509	membrane protein ectodomain proteolysis	1.372098e-3
GO:0032352	positive regulation of hormone metabolic process	1.390539e-3
GO:0032402	melanosome transport	1.433538e-3
GO:0022409	positive regulation of cell-cell adhesion	1.451712e-3
GO:0009991	response to extracellular stimulus	1.471113e-3
GO:0034341	response to interferon-gamma	1.496440e-3
GO:0071104	response to interleukin-9	1.504978e-3
GO:0002730	regulation of dendritic cell cytokine production	1.504978e-3
GO:0048313	Golgi inheritance	1.504978e-3
GO:0006221	pyrimidine nucleotide biosynthetic process	1.562942e-3
GO:0045623	negative regulation of T-helper cell differentiation	1.580430e-3
GO:0048745	smooth muscle tissue development	1.584698e-3
GO:0052547	regulation of peptidase activity	1.605254e-3
GO:0070887	cellular response to chemical stimulus	1.625196e-3
GO:0006606	protein import into nucleus	1.648512e-3
GO:0008052	sensory organ boundary specification	1.735632e-3
GO:0007402	ganglion mother cell fate determination	1.735632e-3
GO:0021610	facial nerve morphogenesis	1.753965e-3
GO:0061370	testosterone biosynthetic process	1.780632e-3
GO:0033619	membrane protein proteolysis	1.782925e-3
GO:0021612	facial nerve structural organization	1.910734e-3
GO:0042346	positive regulation of NF-kappaB import into nucleus	1.940574e-3
GO:0034698	response to gonadotropin stimulus	1.959993e-3
GO:0017038	protein import	1.962351e-3
GO:0043243	positive regulation of protein complex disassembly	1.963996e-3
GO:0031111	negative regulation of microtubule polymerization or depolymerization	1.988479e-3
GO:0032376	positive regulation of cholesterol transport	2.018758e-3
GO:0006686	sphingomyelin biosynthetic process	2.018758e-3
GO:0015711	organic anion transport	2.064083e-3
GO:0006006	glucose metabolic process	2.076206e-3
GO:0016560	protein import into peroxisome matrix, docking	2.114373e-3
GO:0000729	DNA double-strand break processing	2.114373e-3
GO:0021546	rhombomere development	2.140060e-3
GO:0031645	negative regulation of neurological system process	2.160864e-3
GO:0021766	hippocampus development	2.238431e-3
GO:0042428	serotonin metabolic process	2.271696e-3
GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	2.311668e-3
GO:0046855	inositol phosphate dephosphorylation	2.332795e-3
GO:0033591	response to L-ascorbic acid	2.381274e-3
GO:0051896	regulation of protein kinase B signaling cascade	2.399181e-3
GO:0021854	hypothalamus development	2.469522e-3
GO:0031959	mineralocorticoid receptor signaling pathway	2.488877e-3
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	2.541066e-3
GO:0051170	nuclear import	2.647265e-3
GO:0009132	nucleoside diphosphate metabolic process	2.650210e-3
GO:0042631	cellular response to water deprivation	2.660681e-3
GO:0006104	succinyl-CoA metabolic process	2.660681e-3
GO:0010033	response to organic substance	2.682121e-3
GO:0031442	positive regulation of mRNA 3'-end processing	2.686514e-3
GO:0006506	GPI anchor biosynthetic process	2.695540e-3
GO:0032092	positive regulation of protein binding	2.745096e-3
GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	2.791531e-3
GO:0021561	facial nerve development	2.791531e-3
GO:0090030	regulation of steroid hormone biosynthetic process	2.794469e-3
GO:0032656	regulation of interleukin-13 production	2.798833e-3
GO:0045056	transcytosis	2.890578e-3
GO:0072528	pyrimidine-containing compound biosynthetic process	2.901931e-3
GO:0072321	chaperone-mediated protein transport	2.906514e-3
GO:0033345	asparagine catabolic process via L-aspartate	2.906514e-3
GO:0051705	behavioral interaction between organisms	2.924777e-3
GO:0051414	response to cortisol stimulus	2.971850e-3
GO:0071902	positive regulation of protein serine/threonine kinase activity	2.986001e-3
GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis	3.032952e-3
GO:0045542	positive regulation of cholesterol biosynthetic process	3.044698e-3
GO:0030388	fructose 1,6-bisphosphate metabolic process	3.044698e-3
GO:0051693	actin filament capping	3.121101e-3
GO:0030835	negative regulation of actin filament depolymerization	3.258868e-3
GO:0045624	positive regulation of T-helper cell differentiation	3.265716e-3
GO:0009220	pyrimidine ribonucleotide biosynthetic process	3.278401e-3
GO:0000187	activation of MAPK activity	3.314470e-3
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	3.314607e-3
GO:0031333	negative regulation of protein complex assembly	3.368463e-3
GO:0042508	tyrosine phosphorylation of Stat1 protein	3.369605e-3
GO:0031658	negative regulation of cyclin-dependent protein kinase activity involved in G1/S	3.369605e-3
GO:0007092	activation of mitotic anaphase-promoting complex activity	3.369605e-3
GO:0045626	negative regulation of T-helper 1 cell differentiation	3.396737e-3
GO:0002125	maternal aggressive behavior	3.396737e-3
GO:0015993	molecular hydrogen transport	3.415291e-3
GO:0010793	regulation of mRNA export from nucleus	3.415291e-3
GO:0060420	regulation of heart growth	3.464459e-3
GO:0014070	response to organic cyclic compound	3.521751e-3
GO:0030148	sphingolipid biosynthetic process	3.545214e-3
GO:0045921	positive regulation of exocytosis	3.554212e-3
GO:0006907	pinocytosis	3.743709e-3
GO:0033574	response to testosterone stimulus	3.757690e-3
GO:0043244	regulation of protein complex disassembly	3.787137e-3
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	3.880417e-3
GO:0042713	sperm ejaculation	3.880417e-3
GO:0031668	cellular response to extracellular stimulus	3.959973e-3
GO:0045940	positive regulation of steroid metabolic process	3.973098e-3
GO:0000165	MAPKKK cascade	4.013611e-3
GO:0009629	response to gravity	4.021133e-3
GO:0006493	protein O-linked glycosylation	4.110571e-3
GO:0046639	negative regulation of alpha-beta T cell differentiation	4.146630e-3
GO:0060416	response to growth hormone stimulus	4.152795e-3
GO:0034504	protein localization to nucleus	4.220345e-3
GO:0050908	detection of light stimulus involved in visual perception	4.231454e-3
GO:0060012	synaptic transmission, glycinergic	4.245545e-3
GO:0032203	telomere formation via telomerase	4.245545e-3
GO:0071392	cellular response to estradiol stimulus	4.374704e-3
GO:0048024	regulation of nuclear mRNA splicing, via spliceosome	4.383082e-3
GO:0007622	rhythmic behavior	4.383082e-3
GO:0060333	interferon-gamma-mediated signaling pathway	4.441159e-3
GO:0060152	microtubule-based peroxisome localization	4.441159e-3
GO:0051127	positive regulation of actin nucleation	4.441159e-3
GO:0046467	membrane lipid biosynthetic process	4.443396e-3
GO:0009218	pyrimidine ribonucleotide metabolic process	4.556643e-3
GO:0006885	regulation of pH	4.569594e-3
GO:0009451	RNA modification	4.595029e-3
GO:0051494	negative regulation of cytoskeleton organization	4.612254e-3
GO:0048305	immunoglobulin secretion	4.641744e-3
GO:0045767	regulation of anti-apoptosis	4.681772e-3
GO:0050863	regulation of T cell activation	4.742729e-3
GO:0003417	growth plate cartilage development	4.908729e-3
GO:0032674	regulation of interleukin-5 production	4.955338e-3
GO:0051225	spindle assembly	4.984077e-3
GO:0010638	positive regulation of organelle organization	4.994223e-3
GO:0071243	cellular response to arsenic-containing substance	5.022481e-3
GO:0030520	estrogen receptor signaling pathway	5.127045e-3
GO:0008216	spermidine metabolic process	5.211825e-3
GO:0031440	regulation of mRNA 3'-end processing	5.303370e-3
GO:0014910	regulation of smooth muscle cell migration	5.339788e-3
GO:0042133	neurotransmitter metabolic process	5.442491e-3
GO:0055021	regulation of cardiac muscle tissue growth	5.549822e-3
GO:0007186	G-protein coupled receptor protein signaling pathway	5.556252e-3
GO:0021572	rhombomere 6 development	5.600555e-3
GO:0061078	positive regulation of prostaglandin secretion involved in immune response	5.600555e-3
GO:0061004	pattern specification involved in kidney development	5.643529e-3
GO:0007379	segment specification	5.858304e-3
GO:0045580	regulation of T cell differentiation	5.883527e-3
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	5.938598e-3
GO:0022406	membrane docking	5.999465e-3
GO:0021569	rhombomere 3 development	6.029824e-3
GO:0002689	negative regulation of leukocyte chemotaxis	6.029824e-3
GO:0030104	water homeostasis	6.197606e-3
GO:0050756	fractalkine metabolic process	6.299747e-3
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	6.299747e-3
GO:0006701	progesterone biosynthetic process	6.299747e-3
GO:0003061	positive regulation of the force of heart contraction by norepinephrine	6.299747e-3
GO:0033595	response to genistein	6.299747e-3
GO:0001732	formation of translation initiation complex	6.444068e-3
GO:0033059	cellular pigmentation	6.452934e-3
GO:0031669	cellular response to nutrient levels	6.484621e-3
GO:0006661	phosphatidylinositol biosynthetic process	6.741535e-3
GO:0060676	ureteric bud formation	6.762119e-3
GO:0001522	pseudouridine synthesis	6.762119e-3
GO:0070633	transepithelial transport	6.765301e-3
GO:0032753	positive regulation of interleukin-4 production	6.765301e-3
GO:0007088	regulation of mitosis	6.847265e-3
GO:0001510	RNA methylation	6.924168e-3
GO:0071900	regulation of protein serine/threonine kinase activity	6.962128e-3
GO:0006220	pyrimidine nucleotide metabolic process	6.972519e-3
GO:0071545	inositol phosphate catabolic process	7.081773e-3
GO:0031110	regulation of microtubule polymerization or depolymerization	7.100342e-3
GO:0032400	melanosome localization	7.169191e-3
GO:0070669	response to interleukin-2	7.225273e-3
GO:0055099	response to high density lipoprotein particle stimulus	7.225273e-3
GO:0042977	activation of JAK2 kinase activity	7.225273e-3
GO:0021955	central nervous system neuron axonogenesis	7.410224e-3
GO:0070507	regulation of microtubule cytoskeleton organization	7.482089e-3
GO:0072592	oxygen metabolic process	7.512958e-3
GO:0002702	positive regulation of production of molecular mediator of immune response	7.606683e-3
GO:0006611	protein export from nucleus	7.613762e-3
GO:0006684	sphingomyelin metabolic process	7.626923e-3
GO:0033043	regulation of organelle organization	7.783615e-3
GO:0016447	somatic recombination of immunoglobulin gene segments	7.796303e-3
GO:0060080	regulation of inhibitory postsynaptic membrane potential	8.037354e-3
GO:0071548	response to dexamethasone stimulus	8.111803e-3
GO:0055012	ventricular cardiac muscle cell differentiation	8.253334e-3
GO:0009438	methylglyoxal metabolic process	8.265927e-3
GO:0071496	cellular response to external stimulus	8.321316e-3
GO:0021801	cerebral cortex radial glia guided migration	8.499345e-3
GO:0030853	negative regulation of granulocyte differentiation	8.499345e-3
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	8.651594e-3
GO:0033490	cholesterol biosynthetic process via lathosterol	8.854614e-3
GO:0090342	regulation of cell aging	8.943119e-3
GO:0032224	positive regulation of synaptic transmission, cholinergic	8.969244e-3
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	8.969244e-3
GO:0008612	peptidyl-lysine modification to hypusine	8.969244e-3
GO:0045454	cell redox homeostasis	9.108880e-3
GO:0061013	regulation of mRNA catabolic process	9.108932e-3
GO:0007600	sensory perception	9.147465e-3
GO:0014850	response to muscle activity	9.189967e-3
GO:0006820	anion transport	9.199339e-3
GO:0030155	regulation of cell adhesion	9.262253e-3
GO:0002684	positive regulation of immune system process	9.330772e-3
GO:0002828	regulation of type 2 immune response	9.470389e-3
GO:0021761	limbic system development	9.477384e-3
GO:0032200	telomere organization	9.663102e-3
GO:0051438	regulation of ubiquitin-protein ligase activity	9.753281e-3
GO:0007254	JNK cascade	9.818783e-3
GO:0046856	phosphatidylinositol dephosphorylation	9.827400e-3
GO:0042503	tyrosine phosphorylation of Stat3 protein	9.935460e-3
GO:0051099	positive regulation of binding	9.945925e-3
GO:0002719	negative regulation of cytokine production involved in immune response	1.000233e-2
GO:0030540	female genitalia development	1.016102e-2
GO:0001967	suckling behavior	1.042482e-2
GO:0046839	phospholipid dephosphorylation	1.054382e-2
GO:0001503	ossification	1.057956e-2
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	1.066649e-2
GO:0019748	secondary metabolic process	1.071800e-2
GO:0008210	estrogen metabolic process	1.082488e-2
GO:0030834	regulation of actin filament depolymerization	1.086725e-2
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	1.096666e-2
GO:0050432	catecholamine secretion	1.111258e-2
GO:0042312	regulation of vasodilation	1.126866e-2
GO:0032784	regulation of transcription elongation, DNA-dependent	1.131464e-2
GO:0030183	B cell differentiation	1.132669e-2
GO:0035768	endothelial cell chemotaxis to fibroblast growth factor	1.138685e-2
GO:0035754	B cell chemotaxis	1.138685e-2
GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	1.138685e-2
GO:0009068	aspartate family amino acid catabolic process	1.148352e-2
GO:0010738	regulation of protein kinase A signaling cascade	1.148487e-2
GO:0071385	cellular response to glucocorticoid stimulus	1.149218e-2
GO:0005975	carbohydrate metabolic process	1.150871e-2
GO:0016445	somatic diversification of immunoglobulins	1.176639e-2
GO:0042506	tyrosine phosphorylation of Stat5 protein	1.193357e-2
GO:0019605	butyrate metabolic process	1.193357e-2
GO:0001550	ovarian cumulus expansion	1.193357e-2
GO:0001660	fever generation	1.193357e-2
GO:0006497	protein lipidation	1.211593e-2
GO:0019318	hexose metabolic process	1.231364e-2
GO:0043044	ATP-dependent chromatin remodeling	1.251211e-2
GO:0051781	positive regulation of cell division	1.261267e-2
GO:0022408	negative regulation of cell-cell adhesion	1.272267e-2
GO:0050810	regulation of steroid biosynthetic process	1.273163e-2
GO:0030431	sleep	1.275423e-2
GO:0002825	regulation of T-helper 1 type immune response	1.275423e-2
GO:0055067	monovalent inorganic cation homeostasis	1.276928e-2
GO:0033151	V(D)J recombination	1.279229e-2
GO:0045582	positive regulation of T cell differentiation	1.281075e-2
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	1.294284e-2
GO:0042345	regulation of NF-kappaB import into nucleus	1.305453e-2
GO:0035024	negative regulation of Rho protein signal transduction	1.311316e-2
GO:0097012	response to granulocyte macrophage colony-stimulating factor stimulus	1.322995e-2
GO:0044091	membrane biogenesis	1.322995e-2
GO:0032693	negative regulation of interleukin-10 production	1.322995e-2
GO:0005513	detection of calcium ion	1.324308e-2
GO:0042221	response to chemical stimulus	1.329420e-2
GO:0051340	regulation of ligase activity	1.345675e-2
GO:0010907	positive regulation of glucose metabolic process	1.358734e-2
GO:0043406	positive regulation of MAP kinase activity	1.363640e-2
GO:0046325	negative regulation of glucose import	1.378674e-2
GO:0006399	tRNA metabolic process	1.391409e-2
GO:0032271	regulation of protein polymerization	1.410395e-2
GO:0002701	negative regulation of production of molecular mediator of immune response	1.424834e-2
GO:0033554	cellular response to stress	1.429287e-2
GO:0006400	tRNA modification	1.444060e-2
GO:0021783	preganglionic parasympathetic nervous system development	1.444060e-2
GO:0010982	regulation of high-density lipoprotein particle clearance	1.446480e-2
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	1.477749e-2
GO:0046885	regulation of hormone biosynthetic process	1.480408e-2
GO:0042129	regulation of T cell proliferation	1.487617e-2
GO:2001051	positive regulation of tendon cell differentiation	1.493968e-2
GO:0033182	regulation of histone ubiquitination	1.493968e-2
GO:0021509	roof plate formation	1.493968e-2
GO:0051155	positive regulation of striated muscle cell differentiation	1.512677e-2
GO:0090316	positive regulation of intracellular protein transport	1.521431e-2
GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.546975e-2
GO:0007213	muscarinic acetylcholine receptor signaling pathway	1.553860e-2
GO:0006598	polyamine catabolic process	1.555301e-2
GO:0043380	regulation of memory T cell differentiation	1.577014e-2
GO:0010829	negative regulation of glucose transport	1.603532e-2
GO:0015816	glycine transport	1.620918e-2
GO:0042092	type 2 immune response	1.620918e-2
GO:0046488	phosphatidylinositol metabolic process	1.630353e-2
GO:0005979	regulation of glycogen biosynthetic process	1.643051e-2
GO:0031098	stress-activated protein kinase signaling cascade	1.656203e-2
GO:0032388	positive regulation of intracellular transport	1.683467e-2
GO:0044262	cellular carbohydrate metabolic process	1.711168e-2
GO:0035722	interleukin-12-mediated signaling pathway	1.714713e-2
GO:0010561	negative regulation of glycoprotein biosynthetic process	1.714713e-2
GO:0010559	regulation of glycoprotein biosynthetic process	1.725524e-2
GO:0060324	face development	1.729101e-2
GO:0055024	regulation of cardiac muscle tissue development	1.735877e-2
GO:0008584	male gonad development	1.745158e-2
GO:0051290	protein heterotetramerization	1.755934e-2
GO:0046878	positive regulation of saliva secretion	1.756881e-2
GO:0032202	telomere assembly	1.756881e-2
GO:0006302	double-strand break repair	1.760246e-2