Novel motif:130

name:	motif130_TTTCAAACNCCC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0042074	cell migration involved in gastrulation	3.459862e-13
GO:0006020	inositol metabolic process	1.026231e-12
GO:0034377	plasma lipoprotein particle assembly	3.705502e-11
GO:0008078	mesodermal cell migration	3.991508e-11
GO:0034379	very-low-density lipoprotein particle assembly	3.994037e-10
GO:0010269	response to selenium ion	1.253411e-9
GO:0000185	activation of MAPKKK activity	1.403009e-9
GO:0007509	mesoderm migration involved in gastrulation	8.210488e-9
GO:0051901	positive regulation of mitochondrial depolarization	1.561253e-8
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	2.936635e-8
GO:0002889	regulation of immunoglobulin mediated immune response	3.948306e-8
GO:0032964	collagen biosynthetic process	4.961207e-8
GO:0001957	intramembranous ossification	7.044383e-8
GO:0002712	regulation of B cell mediated immunity	7.541009e-8
GO:0031536	positive regulation of exit from mitosis	7.637238e-8
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	1.541378e-7
GO:0046543	development of secondary female sexual characteristics	1.774175e-7
GO:0019751	polyol metabolic process	1.985985e-7
GO:0000075	cell cycle checkpoint	2.125569e-7
GO:0006689	ganglioside catabolic process	3.270192e-7
GO:0003307	regulation of Wnt receptor signaling pathway involved in heart development	4.478891e-7
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	6.450902e-7
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	6.598272e-7
GO:0010954	positive regulation of protein processing	6.898868e-7
GO:0035814	negative regulation of renal sodium excretion	6.952313e-7
GO:0071156	regulation of cell cycle arrest	6.993046e-7
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	7.621984e-7
GO:0045136	development of secondary sexual characteristics	9.100880e-7
GO:0071316	cellular response to nicotine	1.095117e-6
GO:0048853	forebrain morphogenesis	1.260072e-6
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	1.303206e-6
GO:0070245	positive regulation of thymocyte apoptosis	1.430519e-6
GO:0070230	positive regulation of lymphocyte apoptosis	1.442893e-6
GO:0070417	cellular response to cold	1.740725e-6
GO:0070243	regulation of thymocyte apoptosis	1.981187e-6
GO:0060167	regulation of adenosine receptor signaling pathway	2.124738e-6
GO:0033555	multicellular organismal response to stress	2.288917e-6
GO:0042542	response to hydrogen peroxide	3.021802e-6
GO:0030514	negative regulation of BMP signaling pathway	3.403390e-6
GO:0070234	positive regulation of T cell apoptosis	3.573805e-6
GO:0022027	interkinetic nuclear migration	3.762978e-6
GO:0055093	response to hyperoxia	5.092982e-6
GO:0031133	regulation of axon diameter	5.432785e-6
GO:0007093	mitotic cell cycle checkpoint	6.711649e-6
GO:0043585	nose morphogenesis	7.117160e-6
GO:0033590	response to cobalamin	7.449616e-6
GO:0006117	acetaldehyde metabolic process	7.449616e-6
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	7.504429e-6
GO:0043320	natural killer cell degranulation	7.697330e-6
GO:0003308	negative regulation of Wnt receptor signaling pathway involved in heart development	8.161387e-6
GO:0007051	spindle organization	8.183523e-6
GO:0070232	regulation of T cell apoptosis	8.421221e-6
GO:0060343	trabecula formation	8.658899e-6
GO:0006097	glyoxylate cycle	8.982419e-6
GO:0051293	establishment of spindle localization	9.051827e-6
GO:0035419	activation of MAPK activity involved in innate immune response	9.138965e-6
GO:0034389	lipid particle organization	9.160432e-6
GO:0046491	L-methylmalonyl-CoA metabolic process	9.755547e-6
GO:0016554	cytidine to uridine editing	9.755547e-6
GO:0045191	regulation of isotype switching	1.018181e-5
GO:0035556	intracellular signal transduction	1.164228e-5
GO:0042159	lipoprotein catabolic process	1.176892e-5
GO:0000077	DNA damage checkpoint	1.182433e-5
GO:0002739	regulation of cytokine secretion involved in immune response	1.208909e-5
GO:0031627	telomeric loop formation	1.281151e-5
GO:0035121	tail morphogenesis	1.383272e-5
GO:0050768	negative regulation of neurogenesis	1.540835e-5
GO:0042360	vitamin E metabolic process	1.574042e-5
GO:0030844	positive regulation of intermediate filament depolymerization	1.574042e-5
GO:0042596	fear response	1.583964e-5
GO:0032926	negative regulation of activin receptor signaling pathway	1.586138e-5
GO:0061383	trabecula morphogenesis	1.592792e-5
GO:0030510	regulation of BMP signaling pathway	1.598767e-5
GO:0009264	deoxyribonucleotide catabolic process	1.600725e-5
GO:0030953	astral microtubule organization	1.655955e-5
GO:0009155	purine deoxyribonucleotide catabolic process	1.692276e-5
GO:0002740	negative regulation of cytokine secretion involved in immune response	1.740071e-5
GO:0090081	regulation of heart induction by regulation of canonical Wnt receptor signaling pathway	1.753528e-5
GO:0019882	antigen processing and presentation	1.870326e-5
GO:0046853	inositol or phosphatidylinositol phosphorylation	1.927763e-5
GO:0060389	pathway-restricted SMAD protein phosphorylation	1.983906e-5
GO:0060346	bone trabecula formation	2.124672e-5
GO:0007626	locomotory behavior	2.351911e-5
GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	2.352729e-5
GO:0006779	porphyrin-containing compound biosynthetic process	3.172620e-5
GO:0000302	response to reactive oxygen species	3.208790e-5
GO:0045065	cytotoxic T cell differentiation	3.490473e-5
GO:0071206	establishment of protein localization to juxtaparanode region of axon	3.552397e-5
GO:0060168	positive regulation of adenosine receptor signaling pathway	3.552397e-5
GO:0030149	sphingolipid catabolic process	3.562944e-5
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	3.577875e-5
GO:0021509	roof plate formation	4.045209e-5
GO:0032536	regulation of cell projection size	4.079373e-5
GO:0071300	cellular response to retinoic acid	4.115629e-5
GO:0007605	sensory perception of sound	4.260634e-5
GO:0060744	mammary gland branching involved in thelarche	4.438851e-5
GO:0045416	positive regulation of interleukin-8 biosynthetic process	4.644057e-5
GO:0006285	base-excision repair, AP site formation	4.727291e-5
GO:0046479	glycosphingolipid catabolic process	4.764168e-5
GO:0042267	natural killer cell mediated cytotoxicity	5.080972e-5
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	5.336818e-5
GO:0000722	telomere maintenance via recombination	5.447727e-5
GO:0006312	mitotic recombination	5.510234e-5
GO:0031860	telomeric 3' overhang formation	5.536820e-5
GO:0048592	eye morphogenesis	5.558396e-5
GO:0032924	activin receptor signaling pathway	5.619330e-5
GO:0046501	protoporphyrinogen IX metabolic process	5.661484e-5
GO:0045682	regulation of epidermis development	5.768570e-5
GO:0045007	depurination	5.769286e-5
GO:0010994	free ubiquitin chain polymerization	5.769286e-5
GO:0071312	cellular response to alkaloid	5.875769e-5
GO:0034505	tooth mineralization	5.938971e-5
GO:0006499	N-terminal protein myristoylation	5.981674e-5
GO:0031570	DNA integrity checkpoint	6.110909e-5
GO:0031064	negative regulation of histone deacetylation	6.119571e-5
GO:0044319	wound healing, spreading of cells	6.122791e-5
GO:0045994	positive regulation of translational initiation by iron	6.318061e-5
GO:0002037	negative regulation of L-glutamate transport	6.318061e-5
GO:0042137	sequestering of neurotransmitter	6.493966e-5
GO:0035023	regulation of Rho protein signal transduction	6.770801e-5
GO:0040001	establishment of mitotic spindle localization	6.782551e-5
GO:0003254	regulation of membrane depolarization	7.137611e-5
GO:0038007	netrin-activated signaling pathway	7.147945e-5
GO:0007266	Rho protein signal transduction	7.181259e-5
GO:0051260	protein homooligomerization	7.249038e-5
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	7.624930e-5
GO:0090130	tissue migration	8.271145e-5
GO:0046931	pore complex assembly	8.377495e-5
GO:0009062	fatty acid catabolic process	8.536066e-5
GO:0007265	Ras protein signal transduction	8.767794e-5
GO:0051532	regulation of NFAT protein import into nucleus	8.813409e-5
GO:0051896	regulation of protein kinase B signaling cascade	8.937593e-5
GO:0019230	proprioception	9.189377e-5
GO:0009151	purine deoxyribonucleotide metabolic process	9.881740e-5
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.001730e-4
GO:0060621	negative regulation of cholesterol import	1.004798e-4
GO:0034384	high-density lipoprotein particle clearance	1.013728e-4
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	1.018117e-4
GO:0060157	urinary bladder development	1.027866e-4
GO:0002637	regulation of immunoglobulin production	1.034489e-4
GO:0006635	fatty acid beta-oxidation	1.065727e-4
GO:0002088	lens development in camera-type eye	1.078274e-4
GO:0000132	establishment of mitotic spindle orientation	1.081911e-4
GO:0001909	leukocyte mediated cytotoxicity	1.112993e-4
GO:0060689	cell differentiation involved in salivary gland development	1.123442e-4
GO:0001306	age-dependent response to oxidative stress	1.129610e-4
GO:0033025	regulation of mast cell apoptosis	1.168987e-4
GO:0022616	DNA strand elongation	1.182541e-4
GO:0051798	positive regulation of hair follicle development	1.221972e-4
GO:0000060	protein import into nucleus, translocation	1.279044e-4
GO:0032319	regulation of Rho GTPase activity	1.285876e-4
GO:0000086	G2/M transition of mitotic cell cycle	1.305840e-4
GO:0032862	activation of Rho GTPase activity	1.327488e-4
GO:0051298	centrosome duplication	1.328807e-4
GO:0043243	positive regulation of protein complex disassembly	1.348523e-4
GO:0006447	regulation of translational initiation by iron	1.427113e-4
GO:0009967	positive regulation of signal transduction	1.446405e-4
GO:0050957	equilibrioception	1.531116e-4
GO:0032148	activation of protein kinase B activity	1.549023e-4
GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production	1.605790e-4
GO:0046466	membrane lipid catabolic process	1.649809e-4
GO:0021877	forebrain neuron fate commitment	1.660178e-4
GO:0002861	regulation of inflammatory response to antigenic stimulus	1.672197e-4
GO:0051488	activation of anaphase-promoting complex activity	1.674325e-4
GO:0034380	high-density lipoprotein particle assembly	1.702773e-4
GO:0019048	virus-host interaction	1.703893e-4
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	1.744055e-4
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	1.744055e-4
GO:0016973	poly(A)+ mRNA export from nucleus	1.748874e-4
GO:0051602	response to electrical stimulus	1.774143e-4
GO:0071299	cellular response to vitamin A	1.777338e-4
GO:0042772	DNA damage response, signal transduction resulting in transcription	1.817695e-4
GO:0042994	cytoplasmic sequestering of transcription factor	1.920639e-4
GO:0070159	mitochondrial threonyl-tRNA aminoacylation	1.968711e-4
GO:0001845	phagolysosome assembly	1.984887e-4
GO:0010721	negative regulation of cell development	1.998285e-4
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	2.040187e-4
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	2.104603e-4
GO:0010564	regulation of cell cycle process	2.156503e-4
GO:0060686	negative regulation of prostatic bud formation	2.221145e-4
GO:0048048	embryonic eye morphogenesis	2.290954e-4
GO:0060973	cell migration involved in heart development	2.300566e-4
GO:0007221	positive regulation of transcription of Notch receptor target	2.315967e-4
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	2.320357e-4
GO:0003032	detection of oxygen	2.352051e-4
GO:2000836	positive regulation of androgen secretion	2.426754e-4
GO:0006768	biotin metabolic process	2.426754e-4
GO:2000500	positive regulation of induction of apoptosis in response to chemical stimulus	2.426754e-4
GO:0032526	response to retinoic acid	2.450908e-4
GO:0005980	glycogen catabolic process	2.471656e-4
GO:0010189	vitamin E biosynthetic process	2.474249e-4
GO:0033013	tetrapyrrole metabolic process	2.494567e-4
GO:0071779	G1/S transition checkpoint	2.505278e-4
GO:2000678	negative regulation of transcription regulatory region DNA binding	2.515372e-4
GO:0001662	behavioral fear response	2.549454e-4
GO:0019101	female somatic sex determination	2.615980e-4
GO:0042703	menstruation	2.615980e-4
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	2.636480e-4
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	2.677162e-4
GO:0048320	axial mesoderm formation	2.735408e-4
GO:0060620	regulation of cholesterol import	2.735408e-4
GO:0015824	proline transport	2.754645e-4
GO:0002431	Fc receptor mediated stimulatory signaling pathway	2.754672e-4
GO:0001805	positive regulation of type III hypersensitivity	2.754672e-4
GO:0031848	protection from non-homologous end joining at telomere	2.765684e-4
GO:0072331	signal transduction by p53 class mediator	2.779944e-4
GO:0006471	protein ADP-ribosylation	2.789399e-4
GO:0060816	random inactivation of X chromosome	2.836229e-4
GO:0030330	DNA damage response, signal transduction by p53 class mediator	2.860590e-4
GO:0009258	10-formyltetrahydrofolate catabolic process	2.866199e-4
GO:0051181	cofactor transport	2.888697e-4
GO:0006333	chromatin assembly or disassembly	3.037253e-4
GO:0010874	regulation of cholesterol efflux	3.113046e-4
GO:0007468	regulation of rhodopsin gene expression	3.153197e-4
GO:0072355	histone H3-T3 phosphorylation	3.227257e-4
GO:0008049	male courtship behavior	3.227257e-4
GO:0001963	synaptic transmission, dopaminergic	3.351715e-4
GO:0072329	monocarboxylic acid catabolic process	3.415854e-4
GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway	3.536286e-4
GO:0051955	regulation of amino acid transport	3.610339e-4
GO:0010799	regulation of peptidyl-threonine phosphorylation	3.611372e-4
GO:0045112	integrin biosynthetic process	3.624968e-4
GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint	3.629248e-4
GO:0043589	skin morphogenesis	3.695598e-4
GO:0035966	response to topologically incorrect protein	3.703281e-4
GO:0090082	positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway	3.723830e-4
GO:0006435	threonyl-tRNA aminoacylation	3.723830e-4
GO:0048593	camera-type eye morphogenesis	3.723899e-4
GO:0090381	regulation of heart induction	3.759215e-4
GO:0030825	positive regulation of cGMP metabolic process	3.790349e-4
GO:0045629	negative regulation of T-helper 2 cell differentiation	3.879881e-4
GO:0000212	meiotic spindle organization	3.942859e-4
GO:0032730	positive regulation of interleukin-1 alpha production	3.948805e-4
GO:0071827	plasma lipoprotein particle organization	3.983651e-4
GO:0002089	lens morphogenesis in camera-type eye	3.990391e-4
GO:0051964	negative regulation of synapse assembly	4.242158e-4
GO:0002432	granuloma formation	4.276643e-4
GO:0002209	behavioral defense response	4.293439e-4
GO:0045684	positive regulation of epidermis development	4.306241e-4
GO:2000045	regulation of G1/S transition of mitotic cell cycle	4.515855e-4
GO:0006778	porphyrin-containing compound metabolic process	4.517657e-4
GO:0032321	positive regulation of Rho GTPase activity	4.520780e-4
GO:0006102	isocitrate metabolic process	4.575560e-4
GO:0048265	response to pain	4.584246e-4
GO:0072676	lymphocyte migration	4.614401e-4
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	4.639331e-4
GO:0032963	collagen metabolic process	4.721922e-4
GO:0010826	negative regulation of centrosome duplication	4.889648e-4
GO:0007091	mitotic metaphase/anaphase transition	4.905295e-4
GO:0007243	intracellular protein kinase cascade	5.006351e-4
GO:0051900	regulation of mitochondrial depolarization	5.124336e-4
GO:0019395	fatty acid oxidation	5.141351e-4
GO:0060056	mammary gland involution	5.294053e-4
GO:0051701	interaction with host	5.442138e-4
GO:0006642	triglyceride mobilization	5.459695e-4
GO:0035313	wound healing, spreading of epidermal cells	5.482796e-4
GO:0010875	positive regulation of cholesterol efflux	5.561787e-4
GO:0031575	mitotic cell cycle G1/S transition checkpoint	5.574765e-4
GO:0000272	polysaccharide catabolic process	5.634521e-4
GO:0030859	polarized epithelial cell differentiation	5.742219e-4
GO:0050954	sensory perception of mechanical stimulus	5.797638e-4
GO:0044242	cellular lipid catabolic process	5.798955e-4
GO:0042992	negative regulation of transcription factor import into nucleus	5.905464e-4
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	5.982928e-4
GO:0051259	protein oligomerization	6.275441e-4
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	6.361815e-4
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	6.373013e-4
GO:0014028	notochord formation	6.431738e-4
GO:0006297	nucleotide-excision repair, DNA gap filling	6.516216e-4
GO:0007164	establishment of tissue polarity	6.728535e-4
GO:0071346	cellular response to interferon-gamma	6.898057e-4
GO:0050717	positive regulation of interleukin-1 alpha secretion	7.002067e-4
GO:0035470	positive regulation of vascular wound healing	7.002067e-4
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	7.012723e-4
GO:0000956	nuclear-transcribed mRNA catabolic process	7.164947e-4
GO:0051461	positive regulation of corticotropin secretion	7.171646e-4
GO:0061014	positive regulation of mRNA catabolic process	7.200266e-4
GO:0044247	cellular polysaccharide catabolic process	7.218923e-4
GO:0009251	glucan catabolic process	7.218923e-4
GO:0006783	heme biosynthetic process	7.247659e-4
GO:0002456	T cell mediated immunity	7.330050e-4
GO:0009109	coenzyme catabolic process	7.496320e-4
GO:0006749	glutathione metabolic process	7.530821e-4
GO:0000084	S phase of mitotic cell cycle	7.778495e-4
GO:0048239	negative regulation of DNA recombination at telomere	7.795550e-4
GO:0051320	S phase	7.834211e-4
GO:0050767	regulation of neurogenesis	7.867060e-4
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	7.961347e-4
GO:0001738	morphogenesis of a polarized epithelium	8.026380e-4
GO:0009394	2'-deoxyribonucleotide metabolic process	8.056879e-4
GO:0045471	response to ethanol	8.164649e-4
GO:0051961	negative regulation of nervous system development	8.316050e-4
GO:0010742	macrophage derived foam cell differentiation	8.331190e-4
GO:0048773	erythrophore differentiation	8.331190e-4
GO:0034021	response to silicon dioxide	8.331190e-4
GO:0003069	vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure	8.331190e-4
GO:0001315	age-dependent response to reactive oxygen species	8.331190e-4
GO:0045084	positive regulation of interleukin-12 biosynthetic process	8.392905e-4
GO:0046148	pigment biosynthetic process	8.504187e-4
GO:0006986	response to unfolded protein	8.526403e-4
GO:0072668	tubulin complex biogenesis	8.697396e-4
GO:0060088	auditory receptor cell stereocilium organization	8.793131e-4
GO:0007253	cytoplasmic sequestering of NF-kappaB	8.876815e-4
GO:0003181	atrioventricular valve morphogenesis	8.947012e-4
GO:0014054	positive regulation of gamma-aminobutyric acid secretion	9.053008e-4
GO:0007096	regulation of exit from mitosis	9.066253e-4
GO:0033189	response to vitamin A	9.087525e-4
GO:0002693	positive regulation of cellular extravasation	9.110114e-4
GO:0001707	mesoderm formation	9.306421e-4
GO:0070228	regulation of lymphocyte apoptosis	9.395434e-4
GO:0002407	dendritic cell chemotaxis	9.598353e-4
GO:0061013	regulation of mRNA catabolic process	9.851503e-4
GO:0002072	optic cup morphogenesis involved in camera-type eye development	1.023420e-3
GO:0018993	somatic sex determination	1.031681e-3
GO:0010890	positive regulation of sequestering of triglyceride	1.031681e-3
GO:0061017	hepatoblast differentiation	1.048697e-3
GO:0045199	maintenance of epithelial cell apical/basal polarity	1.048697e-3
GO:0045830	positive regulation of isotype switching	1.054908e-3
GO:2000242	negative regulation of reproductive process	1.068774e-3
GO:0034763	negative regulation of transmembrane transport	1.083022e-3
GO:0003309	type B pancreatic cell differentiation	1.102184e-3
GO:0002883	regulation of hypersensitivity	1.115067e-3
GO:0009057	macromolecule catabolic process	1.115623e-3
GO:0051897	positive regulation of protein kinase B signaling cascade	1.132620e-3
GO:0006271	DNA strand elongation involved in DNA replication	1.135527e-3
GO:0048854	brain morphogenesis	1.140018e-3
GO:0061048	negative regulation of branching involved in lung morphogenesis	1.148372e-3
GO:0060695	negative regulation of cholesterol transporter activity	1.148372e-3
GO:0001812	positive regulation of type I hypersensitivity	1.148372e-3
GO:0042308	negative regulation of protein import into nucleus	1.173611e-3
GO:0044403	symbiosis, encompassing mutualism through parasitism	1.181689e-3
GO:0002074	extraocular skeletal muscle development	1.192138e-3
GO:0033344	cholesterol efflux	1.203081e-3
GO:0050884	neuromuscular process controlling posture	1.203629e-3
GO:0048266	behavioral response to pain	1.203629e-3
GO:0032796	uropod organization	1.203903e-3
GO:0048298	positive regulation of isotype switching to IgA isotypes	1.226007e-3
GO:0035356	cellular triglyceride homeostasis	1.233947e-3
GO:0043132	NAD transport	1.233947e-3
GO:0030421	defecation	1.233947e-3
GO:0001736	establishment of planar polarity	1.247938e-3
GO:0051607	defense response to virus	1.248004e-3
GO:0016571	histone methylation	1.253054e-3
GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity	1.257534e-3
GO:0033032	regulation of myeloid cell apoptosis	1.270360e-3
GO:0032495	response to muramyl dipeptide	1.294728e-3
GO:0043316	cytotoxic T cell degranulation	1.299386e-3
GO:0048332	mesoderm morphogenesis	1.394434e-3
GO:0010812	negative regulation of cell-substrate adhesion	1.396901e-3
GO:0031115	negative regulation of microtubule polymerization	1.403818e-3
GO:0045872	positive regulation of rhodopsin gene expression	1.424896e-3
GO:0010883	regulation of lipid storage	1.431940e-3
GO:0007406	negative regulation of neuroblast proliferation	1.442348e-3
GO:0032633	interleukin-4 production	1.452822e-3
GO:0001865	NK T cell differentiation	1.452822e-3
GO:0045414	regulation of interleukin-8 biosynthetic process	1.453010e-3
GO:0071824	protein-DNA complex subunit organization	1.489058e-3
GO:0046784	intronless viral mRNA export from host nucleus	1.496627e-3
GO:0033628	regulation of cell adhesion mediated by integrin	1.498379e-3
GO:0048011	nerve growth factor receptor signaling pathway	1.499926e-3
GO:0006527	arginine catabolic process	1.503143e-3
GO:0007264	small GTPase mediated signal transduction	1.525739e-3
GO:0071549	cellular response to dexamethasone stimulus	1.531643e-3
GO:0051005	negative regulation of lipoprotein lipase activity	1.563741e-3
GO:0033089	positive regulation of T cell differentiation in thymus	1.626486e-3
GO:0002885	positive regulation of hypersensitivity	1.626486e-3
GO:0002891	positive regulation of immunoglobulin mediated immune response	1.655979e-3
GO:0032008	positive regulation of TOR signaling cascade	1.667256e-3
GO:0005977	glycogen metabolic process	1.685284e-3
GO:0051220	cytoplasmic sequestering of protein	1.685578e-3
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	1.685676e-3
GO:0034614	cellular response to reactive oxygen species	1.686736e-3
GO:0050435	beta-amyloid metabolic process	1.690075e-3
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	1.693151e-3
GO:0003061	positive regulation of the force of heart contraction by norepinephrine	1.693151e-3
GO:2000833	positive regulation of steroid hormone secretion	1.694158e-3
GO:0060117	auditory receptor cell development	1.709787e-3
GO:0045299	otolith mineralization	1.711873e-3
GO:0032790	ribosome disassembly	1.711873e-3
GO:0048147	negative regulation of fibroblast proliferation	1.736481e-3
GO:0022415	viral reproductive process	1.739717e-3
GO:0060601	lateral sprouting from an epithelium	1.741729e-3
GO:0060326	cell chemotaxis	1.747773e-3
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	1.785652e-3
GO:0003272	endocardial cushion formation	1.785652e-3
GO:0007021	tubulin complex assembly	1.785652e-3
GO:0002093	auditory receptor cell morphogenesis	1.806007e-3
GO:0060324	face development	1.829071e-3
GO:0034440	lipid oxidation	1.839111e-3
GO:0021892	cerebral cortex GABAergic interneuron differentiation	1.843228e-3
GO:0050706	regulation of interleukin-1 beta secretion	1.849233e-3
GO:0030237	female sex determination	1.876097e-3
GO:0007499	ectoderm and mesoderm interaction	1.876097e-3
GO:0071379	cellular response to prostaglandin stimulus	1.884715e-3
GO:0010722	regulation of ferrochelatase activity	1.886972e-3
GO:0015734	taurine transport	1.886972e-3
GO:0006848	pyruvate transport	1.886972e-3
GO:0045599	negative regulation of fat cell differentiation	1.887899e-3
GO:0048280	vesicle fusion with Golgi apparatus	1.909409e-3
GO:0071044	histone mRNA catabolic process	1.914263e-3
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	1.922769e-3
GO:0044236	multicellular organismal metabolic process	1.982502e-3
GO:0007346	regulation of mitotic cell cycle	1.988957e-3
GO:0010042	response to manganese ion	1.996661e-3
GO:0070206	protein trimerization	2.059325e-3
GO:0045163	clustering of voltage-gated potassium channels	2.122779e-3
GO:0050704	regulation of interleukin-1 secretion	2.158888e-3
GO:0012501	programmed cell death	2.162106e-3
GO:0061011	hepatic duct development	2.163848e-3
GO:0008334	histone mRNA metabolic process	2.202302e-3
GO:0010043	response to zinc ion	2.215583e-3
GO:0010948	negative regulation of cell cycle process	2.234813e-3
GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway	2.242800e-3
GO:0000910	cytokinesis	2.263193e-3
GO:0032863	activation of Rac GTPase activity	2.319348e-3
GO:0043029	T cell homeostasis	2.326813e-3
GO:0044259	multicellular organismal macromolecule metabolic process	2.335726e-3
GO:0006915	apoptosis	2.347176e-3
GO:0010763	positive regulation of fibroblast migration	2.357961e-3
GO:0016570	histone modification	2.375844e-3
GO:0032376	positive regulation of cholesterol transport	2.376878e-3
GO:0006518	peptide metabolic process	2.381626e-3
GO:0051534	negative regulation of NFAT protein import into nucleus	2.395305e-3
GO:0060197	cloacal septation	2.411659e-3
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	2.411659e-3
GO:0043588	skin development	2.427346e-3
GO:0035993	deltoid tuberosity development	2.449116e-3
GO:0034341	response to interferon-gamma	2.469370e-3
GO:0015816	glycine transport	2.481306e-3
GO:0051881	regulation of mitochondrial membrane potential	2.493989e-3
GO:0007130	synaptonemal complex assembly	2.498241e-3
GO:0071482	cellular response to light stimulus	2.573008e-3
GO:0002706	regulation of lymphocyte mediated immunity	2.581311e-3
GO:0050765	negative regulation of phagocytosis	2.598806e-3
GO:0014826	vein smooth muscle contraction	2.598806e-3
GO:0060026	convergent extension	2.607515e-3
GO:0010888	negative regulation of lipid storage	2.616608e-3
GO:0000154	rRNA modification	2.662756e-3
GO:0007004	telomere maintenance via telomerase	2.701862e-3
GO:0023056	positive regulation of signaling	2.712935e-3
GO:0071985	multivesicular body sorting pathway	2.750087e-3
GO:0034728	nucleosome organization	2.768391e-3
GO:0030823	regulation of cGMP metabolic process	2.770183e-3
GO:0006479	protein methylation	2.785660e-3
GO:0072144	glomerular mesangial cell development	2.797931e-3
GO:0072011	glomerular endothelium development	2.797931e-3
GO:0060035	notochord cell development	2.797931e-3
GO:0007192	activation of adenylate cyclase activity by serotonin receptor signaling pathway	2.797931e-3
GO:0060325	face morphogenesis	2.826569e-3
GO:0010647	positive regulation of cell communication	2.833092e-3
GO:0060022	hard palate development	2.837610e-3
GO:0014013	regulation of gliogenesis	2.839903e-3
GO:0051568	histone H3-K4 methylation	2.844326e-3
GO:0060253	negative regulation of glial cell proliferation	2.858853e-3
GO:0034969	histone arginine methylation	2.909529e-3
GO:0042347	negative regulation of NF-kappaB import into nucleus	2.914301e-3
GO:0000226	microtubule cytoskeleton organization	2.925936e-3
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	2.931904e-3
GO:0023019	signal transduction involved in regulation of gene expression	2.936379e-3
GO:0048850	hypophysis morphogenesis	2.952342e-3
GO:0043217	myelin maintenance	2.960573e-3
GO:0060751	branch elongation involved in mammary gland duct branching	3.030706e-3
GO:0006073	cellular glucan metabolic process	3.070294e-3
GO:0042254	ribosome biogenesis	3.085198e-3
GO:0071356	cellular response to tumor necrosis factor	3.086022e-3
GO:0061325	cell proliferation involved in outflow tract morphogenesis	3.107318e-3
GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis	3.107318e-3
GO:0060127	prolactin secreting cell differentiation	3.107318e-3
GO:0035924	cellular response to vascular endothelial growth factor stimulus	3.160627e-3
GO:0006066	alcohol metabolic process	3.169493e-3
GO:0046112	nucleobase biosynthetic process	3.191481e-3
GO:0010833	telomere maintenance via telomere lengthening	3.206771e-3
GO:0016569	covalent chromatin modification	3.231107e-3
GO:0045604	regulation of epidermal cell differentiation	3.286738e-3
GO:0033026	negative regulation of mast cell apoptosis	3.351137e-3
GO:0072553	terminal button organization	3.379012e-3
GO:0061050	regulation of cell growth involved in cardiac muscle cell development	3.384814e-3
GO:0000093	mitotic telophase	3.392037e-3
GO:0002513	tolerance induction to self antigen	3.423640e-3
GO:0043519	regulation of myosin II filament organization	3.426144e-3
GO:0042440	pigment metabolic process	3.465449e-3
GO:0048319	axial mesoderm morphogenesis	3.514481e-3
GO:0010523	negative regulation of calcium ion transport into cytosol	3.514481e-3
GO:0046110	xanthine metabolic process	3.523191e-3
GO:0048841	regulation of axon extension involved in axon guidance	3.541012e-3
GO:0055025	positive regulation of cardiac muscle tissue development	3.580077e-3
GO:0002418	immune response to tumor cell	3.620354e-3
GO:0019377	glycolipid catabolic process	3.621720e-3
GO:0045839	negative regulation of mitosis	3.635643e-3
GO:0051289	protein homotetramerization	3.662991e-3
GO:0006325	chromatin organization	3.713938e-3
GO:0034694	response to prostaglandin stimulus	3.734729e-3
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	3.754898e-3
GO:0045911	positive regulation of DNA recombination	3.792391e-3
GO:0006817	phosphate ion transport	3.817025e-3
GO:0060561	apoptosis involved in morphogenesis	3.819760e-3
GO:0046578	regulation of Ras protein signal transduction	3.837782e-3
GO:0032851	positive regulation of Rab GTPase activity	3.843445e-3
GO:0042424	catecholamine catabolic process	3.924947e-3
GO:0030509	BMP signaling pathway	3.967184e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0071870	cellular response to catecholamine stimulus	1.674343e-12
GO:0071874	cellular response to norepinephrine stimulus	2.396422e-11
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	3.138666e-10
GO:0031055	chromatin remodeling at centromere	1.713197e-8
GO:0060461	right lung morphogenesis	4.053559e-8
GO:0090131	mesenchyme migration	4.053559e-8
GO:0060446	branching involved in open tracheal system development	4.053559e-8
GO:0014822	detection of wounding	4.053559e-8
GO:0048371	lateral mesodermal cell differentiation	4.053559e-8
GO:0048613	embryonic ectodermal digestive tract morphogenesis	4.053559e-8
GO:0048566	embryonic digestive tract development	4.515185e-8
GO:0045814	negative regulation of gene expression, epigenetic	6.403893e-8
GO:0070245	positive regulation of thymocyte apoptosis	8.155481e-8
GO:0007044	cell-substrate junction assembly	8.759291e-8
GO:0070234	positive regulation of T cell apoptosis	1.328265e-7
GO:0009303	rRNA transcription	2.127390e-7
GO:0019060	intracellular transport of viral proteins in host cell	2.223967e-7
GO:0046967	cytosol to ER transport	2.223967e-7
GO:0000238	zygotene	3.999134e-7
GO:0060948	cardiac vascular smooth muscle cell development	5.196099e-7
GO:0003281	ventricular septum development	5.215539e-7
GO:0032606	type I interferon production	5.915518e-7
GO:0070243	regulation of thymocyte apoptosis	6.721793e-7
GO:0046485	ether lipid metabolic process	9.755894e-7
GO:0070232	regulation of T cell apoptosis	1.064831e-6
GO:0033085	negative regulation of T cell differentiation in thymus	1.497503e-6
GO:0002792	negative regulation of peptide secretion	1.510115e-6
GO:0000165	MAPKKK cascade	1.699809e-6
GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway	2.196196e-6
GO:0060458	right lung development	2.465484e-6
GO:0014819	regulation of skeletal muscle contraction	2.906416e-6
GO:0033993	response to lipid	3.220500e-6
GO:0045580	regulation of T cell differentiation	3.504104e-6
GO:0030818	negative regulation of cAMP biosynthetic process	3.573931e-6
GO:0034329	cell junction assembly	3.575322e-6
GO:0048240	sperm capacitation	3.688100e-6
GO:0097107	postsynaptic density assembly	4.862346e-6
GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	4.862346e-6
GO:0032765	positive regulation of mast cell cytokine production	4.862346e-6
GO:0002431	Fc receptor mediated stimulatory signaling pathway	4.862346e-6
GO:0045060	negative thymic T cell selection	5.389524e-6
GO:0097084	vascular smooth muscle cell development	6.178549e-6
GO:0002649	regulation of tolerance induction to self antigen	6.204285e-6
GO:0033081	regulation of T cell differentiation in thymus	6.441740e-6
GO:0002885	positive regulation of hypersensitivity	6.816704e-6
GO:0034330	cell junction organization	7.201167e-6
GO:0007183	SMAD protein complex assembly	7.647157e-6
GO:2000108	positive regulation of leukocyte apoptosis	8.031377e-6
GO:0031508	centromeric heterochromatin formation	8.308650e-6
GO:0007243	intracellular protein kinase cascade	9.025837e-6
GO:0033026	negative regulation of mast cell apoptosis	9.089057e-6
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	9.588584e-6
GO:0000187	activation of MAPK activity	1.091371e-5
GO:0045351	type I interferon biosynthetic process	1.181233e-5
GO:2000377	regulation of reactive oxygen species metabolic process	1.211363e-5
GO:0045980	negative regulation of nucleotide metabolic process	1.283283e-5
GO:0009988	cell-cell recognition	1.290535e-5
GO:0003279	cardiac septum development	1.344633e-5
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	1.503477e-5
GO:0006473	protein acetylation	1.806055e-5
GO:2000106	regulation of leukocyte apoptosis	1.991878e-5
GO:0090278	negative regulation of peptide hormone secretion	2.308292e-5
GO:0051043	regulation of membrane protein ectodomain proteolysis	2.536567e-5
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	2.709314e-5
GO:0021905	forebrain-midbrain boundary formation	2.709314e-5
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	2.709314e-5
GO:0003322	pancreatic A cell development	2.709314e-5
GO:0006342	chromatin silencing	2.817781e-5
GO:0046638	positive regulation of alpha-beta T cell differentiation	3.221586e-5
GO:0060977	coronary vasculature morphogenesis	3.287492e-5
GO:0070230	positive regulation of lymphocyte apoptosis	3.405586e-5
GO:0006970	response to osmotic stress	3.516998e-5
GO:2000653	regulation of genetic imprinting	3.672006e-5
GO:0043252	sodium-independent organic anion transport	3.672006e-5
GO:0045198	establishment of epithelial cell apical/basal polarity	3.838667e-5
GO:0046124	purine deoxyribonucleoside catabolic process	3.857306e-5
GO:0001778	plasma membrane repair	3.864792e-5
GO:0043383	negative T cell selection	4.024714e-5
GO:0048170	positive regulation of long-term neuronal synaptic plasticity	4.107387e-5
GO:0032148	activation of protein kinase B activity	4.153380e-5
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	4.298311e-5
GO:0090042	tubulin deacetylation	4.500819e-5
GO:0070846	Hsp90 deacetylation	4.500819e-5
GO:0019882	antigen processing and presentation	4.581873e-5
GO:0043525	positive regulation of neuron apoptosis	5.031895e-5
GO:0046676	negative regulation of insulin secretion	5.060579e-5
GO:0070301	cellular response to hydrogen peroxide	5.477781e-5
GO:0034508	centromere complex assembly	5.758335e-5
GO:0090316	positive regulation of intracellular protein transport	6.426036e-5
GO:0003289	atrial septum primum morphogenesis	6.471706e-5
GO:0021773	striatal medium spiny neuron differentiation	6.612153e-5
GO:0008631	induction of apoptosis by oxidative stress	6.612153e-5
GO:0048557	embryonic digestive tract morphogenesis	6.671332e-5
GO:0046373	L-arabinose metabolic process	7.784024e-5
GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway	8.070097e-5
GO:0046637	regulation of alpha-beta T cell differentiation	8.151757e-5
GO:0042307	positive regulation of protein import into nucleus	8.170027e-5
GO:0033025	regulation of mast cell apoptosis	8.925959e-5
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	8.929671e-5
GO:0045627	positive regulation of T-helper 1 cell differentiation	9.245850e-5
GO:0002883	regulation of hypersensitivity	9.703136e-5
GO:0071407	cellular response to organic cyclic compound	9.782421e-5
GO:0042306	regulation of protein import into nucleus	9.942629e-5
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	1.006352e-4
GO:0051222	positive regulation of protein transport	1.061832e-4
GO:0045061	thymic T cell selection	1.078652e-4
GO:0006538	glutamate catabolic process	1.135336e-4
GO:0000387	spliceosomal snRNP assembly	1.135408e-4
GO:0021796	cerebral cortex regionalization	1.135408e-4
GO:0007339	binding of sperm to zona pellucida	1.170678e-4
GO:0060412	ventricular septum morphogenesis	1.261903e-4
GO:0060425	lung morphogenesis	1.288887e-4
GO:0046121	deoxyribonucleoside catabolic process	1.343864e-4
GO:0034764	positive regulation of transmembrane transport	1.363478e-4
GO:0002861	regulation of inflammatory response to antigenic stimulus	1.386996e-4
GO:0043305	negative regulation of mast cell degranulation	1.396256e-4
GO:0042401	cellular biogenic amine biosynthetic process	1.437257e-4
GO:0090076	relaxation of skeletal muscle	1.513966e-4
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	1.513966e-4
GO:0002250	adaptive immune response	1.575178e-4
GO:0045582	positive regulation of T cell differentiation	1.594537e-4
GO:0006346	methylation-dependent chromatin silencing	1.612302e-4
GO:0048041	focal adhesion assembly	1.662524e-4
GO:0003183	mitral valve morphogenesis	1.687366e-4
GO:0043543	protein acylation	1.700665e-4
GO:0071882	activation of phospholipase C activity by adrenergic receptor signaling pathway	1.703301e-4
GO:0071881	inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway	1.703301e-4
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	1.722767e-4
GO:0040029	regulation of gene expression, epigenetic	1.761840e-4
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	1.786003e-4
GO:0002673	regulation of acute inflammatory response	1.789815e-4
GO:0006930	substrate-dependent cell migration, cell extension	1.824943e-4
GO:0045065	cytotoxic T cell differentiation	1.832404e-4
GO:0006475	internal protein amino acid acetylation	1.836949e-4
GO:0046165	alcohol biosynthetic process	1.849725e-4
GO:0046173	polyol biosynthetic process	1.931099e-4
GO:0033617	mitochondrial respiratory chain complex IV assembly	2.014318e-4
GO:0007224	smoothened signaling pathway	2.073311e-4
GO:0045619	regulation of lymphocyte differentiation	2.117773e-4
GO:0051659	maintenance of mitochondrion location	2.121358e-4
GO:0045358	negative regulation of interferon-beta biosynthetic process	2.168786e-4
GO:0021539	subthalamus development	2.234190e-4
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	2.234190e-4
GO:0071418	cellular response to amine stimulus	2.239820e-4
GO:0014009	glial cell proliferation	2.293569e-4
GO:0006044	N-acetylglucosamine metabolic process	2.293569e-4
GO:0006540	glutamate decarboxylation to succinate	2.420344e-4
GO:0060563	neuroepithelial cell differentiation	2.665205e-4
GO:0034502	protein localization to chromosome	2.683848e-4
GO:0042089	cytokine biosynthetic process	2.720443e-4
GO:0021877	forebrain neuron fate commitment	2.843969e-4
GO:0033157	regulation of intracellular protein transport	2.932413e-4
GO:0060463	lung lobe morphogenesis	2.942521e-4
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	2.986606e-4
GO:0050689	negative regulation of defense response to virus by host	2.986606e-4
GO:0018158	protein oxidation	2.986606e-4
GO:0002891	positive regulation of immunoglobulin mediated immune response	3.025459e-4
GO:2000677	regulation of transcription regulatory region DNA binding	3.036878e-4
GO:0071417	cellular response to organic nitrogen	3.050997e-4
GO:0045058	T cell selection	3.054793e-4
GO:2000379	positive regulation of reactive oxygen species metabolic process	3.061743e-4
GO:0000460	maturation of 5.8S rRNA	3.080829e-4
GO:0045581	negative regulation of T cell differentiation	3.128827e-4
GO:0046635	positive regulation of alpha-beta T cell activation	3.146572e-4
GO:0051956	negative regulation of amino acid transport	3.241945e-4
GO:0002922	positive regulation of humoral immune response	3.318224e-4
GO:0001709	cell fate determination	3.483536e-4
GO:0021798	forebrain dorsal/ventral pattern formation	3.489286e-4
GO:0050854	regulation of antigen receptor-mediated signaling pathway	3.497896e-4
GO:0007288	sperm axoneme assembly	3.644494e-4
GO:0060161	positive regulation of dopamine receptor signaling pathway	3.750796e-4
GO:0009817	defense response to fungus, incompatible interaction	3.821769e-4
GO:0071316	cellular response to nicotine	3.852026e-4
GO:0071385	cellular response to glucocorticoid stimulus	3.875213e-4
GO:0007406	negative regulation of neuroblast proliferation	3.929334e-4
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	4.031115e-4
GO:0042421	norepinephrine biosynthetic process	4.031115e-4
GO:0006378	mRNA polyadenylation	4.046662e-4
GO:0018206	peptidyl-methionine modification	4.204434e-4
GO:0018394	peptidyl-lysine acetylation	4.610248e-4
GO:0051054	positive regulation of DNA metabolic process	4.676872e-4
GO:0032846	positive regulation of homeostatic process	4.716473e-4
GO:0060022	hard palate development	5.064240e-4
GO:0072404	signal transduction involved in G1/S transition checkpoint	5.078487e-4
GO:0034616	response to laminar fluid shear stress	5.078487e-4
GO:0051101	regulation of DNA binding	5.113318e-4
GO:0034614	cellular response to reactive oxygen species	5.126985e-4
GO:0002675	positive regulation of acute inflammatory response	5.139955e-4
GO:0008625	induction of apoptosis via death domain receptors	5.216402e-4
GO:0032740	positive regulation of interleukin-17 production	5.376439e-4
GO:0032388	positive regulation of intracellular transport	5.497582e-4
GO:0035036	sperm-egg recognition	5.503174e-4
GO:0040034	regulation of development, heterochronic	5.644324e-4
GO:0060979	vasculogenesis involved in coronary vascular morphogenesis	5.680311e-4
GO:0071222	cellular response to lipopolysaccharide	6.170020e-4
GO:0007254	JNK cascade	6.286995e-4
GO:0072395	signal transduction involved in cell cycle checkpoint	6.295672e-4
GO:0045740	positive regulation of DNA replication	6.314248e-4
GO:0033077	T cell differentiation in thymus	6.346873e-4
GO:0003211	cardiac ventricle formation	6.395392e-4
GO:0000281	cytokinesis after mitosis	6.427828e-4
GO:0034509	centromeric core chromatin assembly	6.519733e-4
GO:0034080	CenH3-containing nucleosome assembly at centromere	6.519733e-4
GO:0031129	inductive cell-cell signaling	6.519733e-4
GO:0001812	positive regulation of type I hypersensitivity	6.520317e-4
GO:0007286	spermatid development	6.543803e-4
GO:0006568	tryptophan metabolic process	6.566946e-4
GO:0018393	internal peptidyl-lysine acetylation	6.627981e-4
GO:2000779	regulation of double-strand break repair	6.635670e-4
GO:0001738	morphogenesis of a polarized epithelium	6.645067e-4
GO:0033160	positive regulation of protein import into nucleus, translocation	6.673805e-4
GO:0016573	histone acetylation	6.687101e-4
GO:0008643	carbohydrate transport	6.787839e-4
GO:0003215	cardiac right ventricle morphogenesis	6.800942e-4
GO:0097022	lymphocyte migration into lymph node	7.094565e-4
GO:0072610	interleukin-12 secretion	7.094565e-4
GO:0045596	negative regulation of cell differentiation	7.179547e-4
GO:0030217	T cell differentiation	7.203748e-4
GO:0048535	lymph node development	7.265590e-4
GO:0033205	cell cycle cytokinesis	7.291102e-4
GO:0060407	negative regulation of penile erection	7.324898e-4
GO:0060169	negative regulation of adenosine receptor signaling pathway	7.324898e-4
GO:2000256	positive regulation of male germ cell proliferation	7.324898e-4
GO:0046111	xanthine biosynthetic process	7.324898e-4
GO:0072355	histone H3-T3 phosphorylation	7.324898e-4
GO:0015739	sialic acid transport	7.324898e-4
GO:0002314	germinal center B cell differentiation	7.324898e-4
GO:0006157	deoxyadenosine catabolic process	7.324898e-4
GO:0009637	response to blue light	7.324898e-4
GO:0042231	interleukin-13 biosynthetic process	7.324898e-4
GO:0046061	dATP catabolic process	7.324898e-4
GO:0090086	negative regulation of protein deubiquitination	7.426680e-4
GO:0046888	negative regulation of hormone secretion	7.503156e-4
GO:0044283	small molecule biosynthetic process	7.535892e-4
GO:2000172	regulation of branching morphogenesis of a nerve	7.721949e-4
GO:0019441	tryptophan catabolic process to kynurenine	7.725829e-4
GO:0060411	cardiac septum morphogenesis	8.183919e-4
GO:0048505	regulation of timing of cell differentiation	8.350406e-4
GO:0042761	very long-chain fatty acid biosynthetic process	8.422990e-4
GO:0048515	spermatid differentiation	8.472294e-4
GO:0070542	response to fatty acid	8.625528e-4
GO:0033037	polysaccharide localization	8.637606e-4
GO:0048002	antigen processing and presentation of peptide antigen	8.797899e-4
GO:0002518	lymphocyte chemotaxis across high endothelial venule	8.821966e-4
GO:0003207	cardiac chamber formation	8.850036e-4
GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	9.142626e-4
GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification	9.237946e-4
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	9.266302e-4
GO:0021983	pituitary gland development	9.276502e-4
GO:0032760	positive regulation of tumor necrosis factor production	9.407132e-4
GO:0043304	regulation of mast cell degranulation	9.575863e-4
GO:0070228	regulation of lymphocyte apoptosis	1.002533e-3
GO:0033132	negative regulation of glucokinase activity	1.010893e-3
GO:0048568	embryonic organ development	1.010913e-3
GO:0051657	maintenance of organelle location	1.015393e-3
GO:2000822	regulation of behavioral fear response	1.019130e-3
GO:2000429	negative regulation of neutrophil aggregation	1.024991e-3
GO:0071638	negative regulation of monocyte chemotactic protein-1 production	1.024991e-3
GO:2000469	negative regulation of peroxidase activity	1.024991e-3
GO:0000027	ribosomal large subunit assembly	1.024991e-3
GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase	1.024991e-3
GO:0035726	common myeloid progenitor cell proliferation	1.024991e-3
GO:0018205	peptidyl-lysine modification	1.069688e-3
GO:0045006	DNA deamination	1.070862e-3
GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification	1.070862e-3
GO:0051052	regulation of DNA metabolic process	1.074163e-3
GO:0017004	cytochrome complex assembly	1.099198e-3
GO:0019049	evasion of host defenses by virus	1.099198e-3
GO:0080164	regulation of nitric oxide metabolic process	1.104933e-3
GO:0060112	generation of ovulation cycle rhythm	1.104933e-3
GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	1.104933e-3
GO:0031347	regulation of defense response	1.109710e-3
GO:0042107	cytokine metabolic process	1.115318e-3
GO:0042538	hyperosmotic salinity response	1.126989e-3
GO:0090322	regulation of superoxide metabolic process	1.133718e-3
GO:0072091	regulation of stem cell proliferation	1.135885e-3
GO:0097026	dendritic cell dendrite assembly	1.136594e-3
GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	1.136594e-3
GO:0006275	regulation of DNA replication	1.155035e-3
GO:0043434	response to peptide hormone stimulus	1.172364e-3
GO:0003357	noradrenergic neuron differentiation	1.220941e-3
GO:0071479	cellular response to ionizing radiation	1.230188e-3
GO:0006351	transcription, DNA-dependent	1.230317e-3
GO:0071779	G1/S transition checkpoint	1.240361e-3
GO:0034105	positive regulation of tissue remodeling	1.240361e-3
GO:0072539	T-helper 17 cell differentiation	1.243302e-3
GO:0045994	positive regulation of translational initiation by iron	1.243302e-3
GO:0061048	negative regulation of branching involved in lung morphogenesis	1.243302e-3
GO:0002037	negative regulation of L-glutamate transport	1.243302e-3
GO:0018199	peptidyl-glutamine modification	1.243302e-3
GO:0034116	positive regulation of heterotypic cell-cell adhesion	1.243302e-3
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	1.277945e-3
GO:0032774	RNA biosynthetic process	1.290561e-3
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.293827e-3
GO:0002003	angiotensin maturation	1.304310e-3
GO:2000648	positive regulation of stem cell proliferation	1.331177e-3
GO:0006955	immune response	1.338351e-3
GO:0042110	T cell activation	1.339017e-3
GO:0046634	regulation of alpha-beta T cell activation	1.372859e-3
GO:0048562	embryonic organ morphogenesis	1.385594e-3
GO:0046649	lymphocyte activation	1.397110e-3
GO:0002376	immune system process	1.397648e-3
GO:0006952	defense response	1.450471e-3
GO:0003348	cardiac endothelial cell differentiation	1.461635e-3
GO:0006633	fatty acid biosynthetic process	1.487369e-3
GO:0050995	negative regulation of lipid catabolic process	1.496530e-3
GO:0031444	slow-twitch skeletal muscle fiber contraction	1.557580e-3
GO:0002175	protein localization to paranode region of axon	1.557580e-3
GO:0045647	negative regulation of erythrocyte differentiation	1.557740e-3
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	1.563401e-3
GO:0060976	coronary vasculature development	1.573801e-3
GO:0045780	positive regulation of bone resorption	1.591822e-3
GO:0030308	negative regulation of cell growth	1.612529e-3
GO:0060413	atrial septum morphogenesis	1.646630e-3
GO:0071356	cellular response to tumor necrosis factor	1.672980e-3
GO:0045321	leukocyte activation	1.694386e-3
GO:0001819	positive regulation of cytokine production	1.708645e-3
GO:0032288	myelin assembly	1.734665e-3
GO:0007184	SMAD protein import into nucleus	1.734665e-3
GO:2000381	negative regulation of mesoderm development	1.754554e-3
GO:0010991	negative regulation of SMAD protein complex assembly	1.754554e-3
GO:0043932	ossification involved in bone remodeling	1.754554e-3
GO:0048714	positive regulation of oligodendrocyte differentiation	1.769526e-3
GO:0006283	transcription-coupled nucleotide-excision repair	1.780603e-3
GO:0048333	mesodermal cell differentiation	1.807446e-3
GO:0031365	N-terminal protein amino acid modification	1.814475e-3
GO:0042255	ribosome assembly	1.841197e-3
GO:0032731	positive regulation of interleukin-1 beta production	1.845034e-3
GO:0045741	positive regulation of epidermal growth factor-activated receptor activity	1.854758e-3
GO:0021978	telencephalon regionalization	1.854758e-3
GO:0000059	protein import into nucleus, docking	1.856809e-3
GO:0051823	regulation of synapse structural plasticity	1.862881e-3
GO:0071803	positive regulation of podosome assembly	1.866148e-3
GO:0035886	vascular smooth muscle cell differentiation	1.881073e-3
GO:0043392	negative regulation of DNA binding	1.890663e-3
GO:0071359	cellular response to dsRNA	1.909056e-3
GO:0009262	deoxyribonucleotide metabolic process	1.918582e-3
GO:0043406	positive regulation of MAP kinase activity	1.927415e-3
GO:0034260	negative regulation of GTPase activity	1.928894e-3
GO:0009719	response to endogenous stimulus	1.930673e-3
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	1.931629e-3
GO:0031018	endocrine pancreas development	1.939571e-3
GO:0032844	regulation of homeostatic process	1.951685e-3
GO:0006114	glycerol biosynthetic process	1.965544e-3
GO:0010741	negative regulation of intracellular protein kinase cascade	1.996084e-3
GO:0003170	heart valve development	2.010005e-3
GO:0031324	negative regulation of cellular metabolic process	2.014121e-3
GO:0071219	cellular response to molecule of bacterial origin	2.077565e-3
GO:0090200	positive regulation of release of cytochrome c from mitochondria	2.078374e-3
GO:0009651	response to salt stress	2.104973e-3
GO:0050862	positive regulation of T cell receptor signaling pathway	2.113272e-3
GO:0090181	regulation of cholesterol metabolic process	2.118563e-3
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	2.136951e-3
GO:0007352	zygotic specification of dorsal/ventral axis	2.164457e-3
GO:0090023	positive regulation of neutrophil chemotaxis	2.173959e-3
GO:0031098	stress-activated protein kinase signaling cascade	2.175305e-3
GO:0045620	negative regulation of lymphocyte differentiation	2.189169e-3
GO:0060557	positive regulation of vitamin D biosynthetic process	2.221441e-3
GO:0003290	atrial septum secundum morphogenesis	2.221441e-3
GO:0002651	positive regulation of tolerance induction to self antigen	2.221441e-3
GO:0001798	positive regulation of type IIa hypersensitivity	2.240318e-3
GO:2000758	positive regulation of peptidyl-lysine acetylation	2.291938e-3
GO:0070845	polyubiquitinated misfolded protein transport	2.301680e-3
GO:0009181	purine ribonucleoside diphosphate catabolic process	2.308073e-3
GO:0070265	necrotic cell death	2.308073e-3
GO:0009120	deoxyribonucleoside metabolic process	2.308073e-3
GO:0003195	tricuspid valve formation	2.308073e-3
GO:0030497	fatty acid elongation	2.330872e-3
GO:2000679	positive regulation of transcription regulatory region DNA binding	2.348813e-3
GO:0046822	regulation of nucleocytoplasmic transport	2.365769e-3
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	2.374896e-3
GO:0015870	acetylcholine transport	2.410859e-3
GO:0006950	response to stress	2.435792e-3
GO:0035640	exploration behavior	2.575841e-3
GO:0071216	cellular response to biotic stimulus	2.580599e-3
GO:0006515	misfolded or incompletely synthesized protein catabolic process	2.606538e-3
GO:0001805	positive regulation of type III hypersensitivity	2.623349e-3
GO:0021879	forebrain neuron differentiation	2.634820e-3
GO:0060426	lung vasculature development	2.704671e-3
GO:0071549	cellular response to dexamethasone stimulus	2.740745e-3
GO:0006094	gluconeogenesis	2.744931e-3
GO:0034261	negative regulation of Ras GTPase activity	2.755211e-3
GO:0006927	transformed cell apoptosis	2.755211e-3
GO:0006105	succinate metabolic process	2.770577e-3
GO:0042254	ribosome biogenesis	2.819338e-3
GO:0032008	positive regulation of TOR signaling cascade	2.884895e-3
GO:0034625	fatty acid elongation, monounsaturated fatty acid	2.892925e-3
GO:0009892	negative regulation of metabolic process	2.897448e-3
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	2.931423e-3
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	2.953969e-3
GO:0043654	recognition of apoptotic cell	2.969341e-3
GO:0045861	negative regulation of proteolysis	2.977148e-3
GO:0000060	protein import into nucleus, translocation	2.977529e-3
GO:0019368	fatty acid elongation, unsaturated fatty acid	2.998604e-3
GO:0032383	regulation of intracellular cholesterol transport	3.045271e-3
GO:0010826	negative regulation of centrosome duplication	3.045271e-3
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	3.052774e-3
GO:0001555	oocyte growth	3.052774e-3
GO:0060947	cardiac vascular smooth muscle cell differentiation	3.055935e-3
GO:0043631	RNA polyadenylation	3.070116e-3
GO:0071346	cellular response to interferon-gamma	3.080861e-3
GO:0009890	negative regulation of biosynthetic process	3.085213e-3
GO:0003231	cardiac ventricle development	3.087843e-3
GO:0010758	regulation of macrophage chemotaxis	3.096068e-3
GO:2000412	positive regulation of thymocyte migration	3.166789e-3
GO:0002449	lymphocyte mediated immunity	3.222340e-3
GO:0007256	activation of JNKK activity	3.323284e-3
GO:0001775	cell activation	3.354534e-3
GO:0045624	positive regulation of T-helper cell differentiation	3.399173e-3
GO:0007141	male meiosis I	3.420371e-3
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	3.420371e-3
GO:0032732	positive regulation of interleukin-1 production	3.488353e-3
GO:2000173	negative regulation of branching morphogenesis of a nerve	3.489136e-3
GO:0070935	3'-UTR-mediated mRNA stabilization	3.489136e-3
GO:0060547	negative regulation of necrotic cell death	3.551089e-3
GO:0071218	cellular response to misfolded protein	3.614047e-3
GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development	3.614047e-3
GO:0032916	positive regulation of transforming growth factor beta3 production	3.614047e-3
GO:0043011	myeloid dendritic cell differentiation	3.630440e-3
GO:0045621	positive regulation of lymphocyte differentiation	3.639505e-3
GO:0048368	lateral mesoderm development	3.641191e-3
GO:0048617	embryonic foregut morphogenesis	3.679138e-3
GO:0051856	adhesion to symbiont	3.684946e-3
GO:0003283	atrial septum development	3.689524e-3
GO:0003205	cardiac chamber development	3.765873e-3
GO:0003179	heart valve morphogenesis	3.784506e-3
GO:2000384	negative regulation of ectoderm development	3.801437e-3
GO:0032386	regulation of intracellular transport	3.803688e-3
GO:0033209	tumor necrosis factor-mediated signaling pathway	3.822071e-3
GO:0033059	cellular pigmentation	3.832714e-3
GO:0060695	negative regulation of cholesterol transporter activity	3.871287e-3
GO:0046102	inosine metabolic process	3.871287e-3
GO:0009217	purine deoxyribonucleoside triphosphate catabolic process	3.871287e-3
GO:0015759	beta-glucoside transport	3.871287e-3
GO:0070267	oncosis	3.925378e-3
GO:0019255	glucose 1-phosphate metabolic process	3.964491e-3
GO:0010457	centriole-centriole cohesion	3.964491e-3
GO:0016070	RNA metabolic process	3.992664e-3
GO:0007173	epidermal growth factor receptor signaling pathway	4.031124e-3
GO:0045089	positive regulation of innate immune response	4.041069e-3
GO:0031349	positive regulation of defense response	4.053139e-3
GO:0046333	octopamine metabolic process	4.085898e-3
GO:0051142	positive regulation of NK T cell proliferation	4.085898e-3
GO:0042309	homoiothermy	4.085898e-3
GO:0032863	activation of Rac GTPase activity	4.104141e-3
GO:0048484	enteric nervous system development	4.184539e-3
GO:0014823	response to activity	4.185051e-3
GO:0006476	protein deacetylation	4.201580e-3
GO:0045908	negative regulation of vasodilation	4.226331e-3
GO:0045989	positive regulation of striated muscle contraction	4.229384e-3
GO:0035910	ascending aorta morphogenesis	4.229686e-3
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	4.229686e-3
GO:0006359	regulation of transcription from RNA polymerase III promoter	4.229686e-3
GO:0006958	complement activation, classical pathway	4.234093e-3
GO:0042345	regulation of NF-kappaB import into nucleus	4.246459e-3
GO:0006366	transcription from RNA polymerase II promoter	4.270504e-3
GO:0002763	positive regulation of myeloid leukocyte differentiation	4.272708e-3
GO:0002791	regulation of peptide secretion	4.313110e-3
GO:0045080	positive regulation of chemokine biosynthetic process	4.354212e-3
GO:0051835	positive regulation of synapse structural plasticity	4.412239e-3
GO:0002683	negative regulation of immune system process	4.433545e-3
GO:0002920	regulation of humoral immune response	4.506940e-3
GO:0035089	establishment of apical/basal cell polarity	4.523061e-3
GO:0009186	deoxyribonucleoside diphosphate metabolic process	4.523061e-3
GO:0001771	immunological synapse formation	4.523061e-3
GO:0090074	negative regulation of protein homodimerization activity	4.526758e-3
GO:0006419	alanyl-tRNA aminoacylation	4.526758e-3
GO:0046823	negative regulation of nucleocytoplasmic transport	4.543533e-3
GO:0031663	lipopolysaccharide-mediated signaling pathway	4.569258e-3
GO:0006586	indolalkylamine metabolic process	4.569258e-3
GO:0010569	regulation of double-strand break repair via homologous recombination	4.588147e-3
GO:0043331	response to dsRNA	4.672948e-3
GO:0032808	lacrimal gland development	4.720146e-3
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	4.887098e-3
GO:0044403	symbiosis, encompassing mutualism through parasitism	4.929592e-3
GO:0050714	positive regulation of protein secretion	4.973205e-3
GO:0035601	protein deacylation	4.986202e-3
GO:0033006	regulation of mast cell activation involved in immune response	5.012371e-3
GO:0002455	humoral immune response mediated by circulating immunoglobulin	5.017139e-3
GO:0006646	phosphatidylethanolamine biosynthetic process	5.070984e-3
GO:0045625	regulation of T-helper 1 cell differentiation	5.070984e-3
GO:0009950	dorsal/ventral axis specification	5.123599e-3
GO:0050868	negative regulation of T cell activation	5.153732e-3
GO:0006576	cellular biogenic amine metabolic process	5.160706e-3
GO:0021536	diencephalon development	5.194502e-3
GO:0034405	response to fluid shear stress	5.197658e-3
GO:0034626	fatty acid elongation, polyunsaturated fatty acid	5.233604e-3
GO:0031394	positive regulation of prostaglandin biosynthetic process	5.238425e-3
GO:0090130	tissue migration	5.323314e-3
GO:0046168	glycerol-3-phosphate catabolic process	5.326636e-3
GO:0043103	hypoxanthine salvage	5.326636e-3
GO:0032261	purine nucleotide salvage	5.326636e-3
GO:0060997	dendritic spine morphogenesis	5.350688e-3
GO:0031581	hemidesmosome assembly	5.367930e-3
GO:0042271	susceptibility to natural killer cell mediated cytotoxicity	5.382580e-3
GO:0006040	amino sugar metabolic process	5.460873e-3
GO:0070509	calcium ion import	5.584498e-3
GO:0003214	cardiac left ventricle morphogenesis	5.605436e-3
GO:0070293	renal absorption	5.619082e-3
GO:0030913	paranodal junction assembly	5.619082e-3