Novel motif:48

name:	motif48_CANTCG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0071673	positive regulation of smooth muscle cell chemotaxis	2.036338e-10
GO:0016570	histone modification	2.655230e-10
GO:0016569	covalent chromatin modification	3.669223e-10
GO:0006348	chromatin silencing at telomere	6.324859e-9
GO:0051299	centrosome separation	6.940516e-9
GO:0071671	regulation of smooth muscle cell chemotaxis	8.130447e-9
GO:0001757	somite specification	1.958976e-8
GO:0060764	cell-cell signaling involved in mammary gland development	3.267861e-8
GO:0033523	histone H2B ubiquitination	9.826067e-8
GO:0060999	positive regulation of dendritic spine development	1.428422e-7
GO:0007549	dosage compensation	2.096005e-7
GO:0006281	DNA repair	3.288894e-7
GO:0035026	leading edge cell differentiation	5.253486e-7
GO:0032060	bleb assembly	5.853792e-7
GO:2000615	regulation of histone H3-K9 acetylation	7.317641e-7
GO:0060430	lung saccule development	7.798340e-7
GO:0034227	tRNA thio-modification	8.347033e-7
GO:0002098	tRNA wobble uridine modification	8.347033e-7
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	1.278172e-6
GO:0060435	bronchiole development	1.521001e-6
GO:0009048	dosage compensation, by inactivation of X chromosome	1.738219e-6
GO:0000416	positive regulation of histone H3-K36 methylation	1.738219e-6
GO:0060482	lobar bronchus development	2.016668e-6
GO:0042696	menarche	3.011241e-6
GO:0045820	negative regulation of glycolysis	3.205810e-6
GO:0070584	mitochondrion morphogenesis	3.475668e-6
GO:0090399	replicative senescence	3.519074e-6
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	4.551229e-6
GO:0042538	hyperosmotic salinity response	4.978622e-6
GO:0051457	maintenance of protein location in nucleus	5.154460e-6
GO:0021759	globus pallidus development	5.371169e-6
GO:0046950	cellular ketone body metabolic process	5.513438e-6
GO:0032472	Golgi calcium ion transport	5.523275e-6
GO:0032468	Golgi calcium ion homeostasis	5.523275e-6
GO:0030026	cellular manganese ion homeostasis	5.523275e-6
GO:0060534	trachea cartilage development	6.749888e-6
GO:0006302	double-strand break repair	8.310254e-6
GO:2001037	positive regulation of tongue muscle cell differentiation	8.408498e-6
GO:0060982	coronary artery morphogenesis	8.408498e-6
GO:0097152	mesenchymal cell apoptosis	8.408498e-6
GO:0051589	negative regulation of neurotransmitter transport	9.065883e-6
GO:0046602	regulation of mitotic centrosome separation	9.270336e-6
GO:0001675	acrosome assembly	9.270433e-6
GO:0060480	lung goblet cell differentiation	1.007628e-5
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	1.016176e-5
GO:0035356	cellular triglyceride homeostasis	1.059083e-5
GO:0051154	negative regulation of striated muscle cell differentiation	1.157353e-5
GO:0043467	regulation of generation of precursor metabolites and energy	1.499124e-5
GO:0060042	retina morphogenesis in camera-type eye	1.691462e-5
GO:0006310	DNA recombination	1.840355e-5
GO:0007379	segment specification	1.919937e-5
GO:2000620	positive regulation of histone H4-K16 acetylation	2.168895e-5
GO:2000617	positive regulation of histone H3-K9 acetylation	2.168895e-5
GO:0070512	positive regulation of histone H4-K20 methylation	2.168895e-5
GO:0048842	positive regulation of axon extension involved in axon guidance	2.188447e-5
GO:0070842	aggresome assembly	2.245845e-5
GO:0018192	enzyme active site formation via L-cysteine persulfide	2.334960e-5
GO:0006482	protein demethylation	2.667085e-5
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	2.703481e-5
GO:0010225	response to UV-C	2.823308e-5
GO:0022412	cellular process involved in reproduction in multicellular organism	3.054249e-5
GO:0060535	trachea cartilage morphogenesis	3.163611e-5
GO:0031297	replication fork processing	3.234890e-5
GO:0021892	cerebral cortex GABAergic interneuron differentiation	3.238991e-5
GO:0016574	histone ubiquitination	3.360570e-5
GO:0016568	chromatin modification	3.368124e-5
GO:0051898	negative regulation of protein kinase B signaling cascade	3.999040e-5
GO:0010890	positive regulation of sequestering of triglyceride	4.181994e-5
GO:0002016	regulation of blood volume by renin-angiotensin	4.382617e-5
GO:0051571	positive regulation of histone H3-K4 methylation	4.888202e-5
GO:0040032	post-embryonic body morphogenesis	4.906675e-5
GO:0060486	Clara cell differentiation	5.268947e-5
GO:0048664	neuron fate determination	5.268947e-5
GO:0060023	soft palate development	5.486734e-5
GO:0035269	protein O-linked mannosylation	5.731060e-5
GO:0006400	tRNA modification	5.731241e-5
GO:0021783	preganglionic parasympathetic nervous system development	5.777760e-5
GO:0060574	intestinal epithelial cell maturation	6.249406e-5
GO:0048561	establishment of organ orientation	6.378266e-5
GO:0046605	regulation of centrosome cycle	7.822619e-5
GO:0046599	regulation of centriole replication	7.932251e-5
GO:0060510	Type II pneumocyte differentiation	9.166467e-5
GO:0060017	parathyroid gland development	9.201402e-5
GO:0035928	rRNA import into mitochondrion	9.242449e-5
GO:2000466	negative regulation of glycogen (starch) synthase activity	1.019570e-4
GO:0042447	hormone catabolic process	1.049875e-4
GO:0000724	double-strand break repair via homologous recombination	1.119337e-4
GO:0000725	recombinational repair	1.121114e-4
GO:0051983	regulation of chromosome segregation	1.315434e-4
GO:0010830	regulation of myotube differentiation	1.335971e-4
GO:0060816	random inactivation of X chromosome	1.381217e-4
GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly	1.492270e-4
GO:0018026	peptidyl-lysine monomethylation	1.546752e-4
GO:0006288	base-excision repair, DNA ligation	1.616130e-4
GO:0001302	replicative cell aging	1.620152e-4
GO:0090346	cellular organofluorine metabolic process	1.726128e-4
GO:0046210	nitric oxide catabolic process	1.726128e-4
GO:0043602	nitrate catabolic process	1.726128e-4
GO:0045685	regulation of glial cell differentiation	1.752341e-4
GO:0048704	embryonic skeletal system morphogenesis	1.850137e-4
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	1.877556e-4
GO:0048486	parasympathetic nervous system development	1.927819e-4
GO:0060876	semicircular canal formation	1.951779e-4
GO:0009648	photoperiodism	1.957521e-4
GO:0060059	embryonic retina morphogenesis in camera-type eye	1.996762e-4
GO:0010390	histone monoubiquitination	1.997782e-4
GO:0051365	cellular response to potassium ion starvation	2.041602e-4
GO:0051645	Golgi localization	2.041602e-4
GO:0016575	histone deacetylation	2.062493e-4
GO:0016254	preassembly of GPI anchor in ER membrane	2.095981e-4
GO:0060465	pharynx development	2.107803e-4
GO:0006013	mannose metabolic process	2.161502e-4
GO:0015891	siderophore transport	2.223391e-4
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	2.281983e-4
GO:0061013	regulation of mRNA catabolic process	2.287995e-4
GO:0000414	regulation of histone H3-K36 methylation	2.349214e-4
GO:0015820	leucine transport	2.548092e-4
GO:0045607	regulation of auditory receptor cell differentiation	2.561686e-4
GO:0034389	lipid particle organization	2.572625e-4
GO:0048713	regulation of oligodendrocyte differentiation	2.612549e-4
GO:0048663	neuron fate commitment	2.788239e-4
GO:0051181	cofactor transport	3.085856e-4
GO:0021675	nerve development	3.098300e-4
GO:0002002	regulation of angiotensin levels in blood	3.130984e-4
GO:0046951	ketone body biosynthetic process	3.158820e-4
GO:0030421	defecation	3.176553e-4
GO:0018022	peptidyl-lysine methylation	3.179647e-4
GO:0021569	rhombomere 3 development	3.204431e-4
GO:0005981	regulation of glycogen catabolic process	3.211246e-4
GO:0050847	progesterone receptor signaling pathway	3.211246e-4
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	3.231510e-4
GO:0015742	alpha-ketoglutarate transport	3.427632e-4
GO:0071503	response to heparin	3.472405e-4
GO:0000413	protein peptidyl-prolyl isomerization	3.496093e-4
GO:0046952	ketone body catabolic process	3.588084e-4
GO:0060850	regulation of transcription involved in cell fate commitment	3.601496e-4
GO:0046293	formaldehyde biosynthetic process	3.617633e-4
GO:0045608	negative regulation of auditory receptor cell differentiation	3.624762e-4
GO:0071584	negative regulation of zinc ion import	3.819796e-4
GO:0090281	negative regulation of calcium ion import	3.819796e-4
GO:0007100	mitotic centrosome separation	3.819796e-4
GO:0045819	positive regulation of glycogen catabolic process	3.861654e-4
GO:0051955	regulation of amino acid transport	3.869092e-4
GO:0010719	negative regulation of epithelial to mesenchymal transition	3.946338e-4
GO:0010986	positive regulation of lipoprotein particle clearance	3.964890e-4
GO:0060347	heart trabecula formation	4.019999e-4
GO:0046600	negative regulation of centriole replication	4.042720e-4
GO:0060356	leucine import	4.165180e-4
GO:0032836	glomerular basement membrane development	4.251438e-4
GO:0007506	gonadal mesoderm development	4.545142e-4
GO:0046939	nucleotide phosphorylation	4.558982e-4
GO:0043457	regulation of cellular respiration	4.678169e-4
GO:0006844	acyl carnitine transport	4.783368e-4
GO:0006308	DNA catabolic process	4.784677e-4
GO:0007344	pronuclear fusion	4.993961e-4
GO:0060433	bronchus development	5.167963e-4
GO:0018208	peptidyl-proline modification	5.451135e-4
GO:0016577	histone demethylation	5.499334e-4
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	5.568147e-4
GO:0070988	demethylation	5.570499e-4
GO:0048752	semicircular canal morphogenesis	5.594658e-4
GO:2001014	regulation of skeletal muscle cell differentiation	5.712673e-4
GO:0043471	regulation of cellular carbohydrate catabolic process	5.865529e-4
GO:0021895	cerebral cortex neuron differentiation	6.205618e-4
GO:0010889	regulation of sequestering of triglyceride	6.360576e-4
GO:0061014	positive regulation of mRNA catabolic process	6.531000e-4
GO:0045655	regulation of monocyte differentiation	6.544051e-4
GO:0060487	lung epithelial cell differentiation	6.634292e-4
GO:0007092	activation of mitotic anaphase-promoting complex activity	6.886609e-4
GO:0031658	negative regulation of cyclin-dependent protein kinase activity involved in G1/S	6.886609e-4
GO:0002882	positive regulation of chronic inflammatory response to non-antigenic stimulus	6.886609e-4
GO:0006044	N-acetylglucosamine metabolic process	7.059444e-4
GO:0071338	positive regulation of hair follicle cell proliferation	7.077078e-4
GO:0021819	layer formation in cerebral cortex	7.077078e-4
GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation	7.119820e-4
GO:0008292	acetylcholine biosynthetic process	7.611654e-4
GO:0021602	cranial nerve morphogenesis	7.634565e-4
GO:0071529	cementum mineralization	8.014088e-4
GO:0018206	peptidyl-methionine modification	8.014088e-4
GO:0010948	negative regulation of cell cycle process	8.023547e-4
GO:0061384	heart trabecular morphogenesis	8.096310e-4
GO:0051569	regulation of histone H3-K4 methylation	8.133423e-4
GO:0051612	negative regulation of serotonin uptake	8.156165e-4
GO:0034968	histone lysine methylation	8.270196e-4
GO:0009886	post-embryonic morphogenesis	8.378160e-4
GO:0010832	negative regulation of myotube differentiation	8.577805e-4
GO:0007522	visceral muscle development	8.904287e-4
GO:0046469	platelet activating factor metabolic process	9.004104e-4
GO:0031573	intra-S DNA damage checkpoint	9.204132e-4
GO:0006325	chromatin organization	9.250747e-4
GO:0006513	protein monoubiquitination	9.456788e-4
GO:0006047	UDP-N-acetylglucosamine metabolic process	9.540061e-4
GO:0007141	male meiosis I	9.540061e-4
GO:0002036	regulation of L-glutamate transport	9.798030e-4
GO:0051276	chromosome organization	9.992279e-4
GO:0007569	cell aging	1.017547e-3
GO:0045657	positive regulation of monocyte differentiation	1.025199e-3
GO:0043414	macromolecule methylation	1.063121e-3
GO:2001054	negative regulation of mesenchymal cell apoptosis	1.128233e-3
GO:0034959	endothelin maturation	1.183278e-3
GO:0010814	substance P catabolic process	1.183278e-3
GO:0010816	calcitonin catabolic process	1.183278e-3
GO:0032581	ER-dependent peroxisome organization	1.228570e-3
GO:0031576	G2/M transition checkpoint	1.277981e-3
GO:0007109	cytokinesis, completion of separation	1.291324e-3
GO:0018198	peptidyl-cysteine modification	1.304434e-3
GO:0071504	cellular response to heparin	1.304434e-3
GO:0034766	negative regulation of ion transmembrane transport	1.385377e-3
GO:0010677	negative regulation of cellular carbohydrate metabolic process	1.401601e-3
GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	1.409712e-3
GO:0051029	rRNA transport	1.411023e-3
GO:0034551	mitochondrial respiratory chain complex III assembly	1.411128e-3
GO:0072595	maintenance of protein localization to organelle	1.433021e-3
GO:0045210	FasL biosynthetic process	1.531406e-3
GO:0097039	protein linear polyubiquitination	1.531406e-3
GO:0000966	RNA 5'-end processing	1.538746e-3
GO:0090075	relaxation of muscle	1.540375e-3
GO:0000072	M phase specific microtubule process	1.620757e-3
GO:0021517	ventral spinal cord development	1.790355e-3
GO:0060977	coronary vasculature morphogenesis	1.848256e-3
GO:0051532	regulation of NFAT protein import into nucleus	1.848375e-3
GO:0007386	compartment pattern specification	1.848375e-3
GO:0006501	C-terminal protein lipidation	1.850427e-3
GO:0043922	negative regulation by host of viral transcription	1.850478e-3
GO:0032007	negative regulation of TOR signaling cascade	1.897099e-3
GO:0007296	vitellogenesis	1.897099e-3
GO:0007097	nuclear migration	1.905079e-3
GO:0072126	positive regulation of glomerular mesangial cell proliferation	1.914101e-3
GO:0071506	cellular response to mycophenolic acid	1.914101e-3
GO:0090239	regulation of histone H4 acetylation	1.961299e-3
GO:0043153	entrainment of circadian clock by photoperiod	1.983169e-3
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	1.990517e-3
GO:0051660	establishment of centrosome localization	2.031979e-3
GO:0021540	corpus callosum morphogenesis	2.031979e-3
GO:0060060	post-embryonic retina morphogenesis in camera-type eye	2.047982e-3
GO:0019358	nicotinate nucleotide salvage	2.142526e-3
GO:0006479	protein methylation	2.201026e-3
GO:0097150	neuronal stem cell maintenance	2.224056e-3
GO:0001921	positive regulation of receptor recycling	2.224056e-3
GO:0060021	palate development	2.250199e-3
GO:0090102	cochlea development	2.287703e-3
GO:0003148	outflow tract septum morphogenesis	2.295519e-3
GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	2.300360e-3
GO:0035461	vitamin transmembrane transport	2.303205e-3
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	2.303205e-3
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	2.303205e-3
GO:0021798	forebrain dorsal/ventral pattern formation	2.322574e-3
GO:0006476	protein deacetylation	2.348175e-3
GO:0090307	spindle assembly involved in mitosis	2.357836e-3
GO:0034699	response to luteinizing hormone stimulus	2.361415e-3
GO:0035166	post-embryonic hemopoiesis	2.401186e-3
GO:0000718	nucleotide-excision repair, DNA damage removal	2.424680e-3
GO:0046292	formaldehyde metabolic process	2.472692e-3
GO:0060177	regulation of angiotensin metabolic process	2.509982e-3
GO:0060318	definitive erythrocyte differentiation	2.569775e-3
GO:0044330	canonical Wnt receptor signaling pathway involved in positive regulation of wound healing	2.600688e-3
GO:0044328	canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration	2.600688e-3
GO:0044329	canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion	2.600688e-3
GO:0034645	cellular macromolecule biosynthetic process	2.602524e-3
GO:0021599	abducens nerve formation	2.611802e-3
GO:0019428	allantoin biosynthetic process	2.611802e-3
GO:0007634	optokinetic behavior	2.611802e-3
GO:0070625	zymogen granule exocytosis	2.631235e-3
GO:0035601	protein deacylation	2.635931e-3
GO:0001990	regulation of systemic arterial blood pressure by hormone	2.660422e-3
GO:0006094	gluconeogenesis	2.711898e-3
GO:0001832	blastocyst growth	2.719824e-3
GO:0006048	UDP-N-acetylglucosamine biosynthetic process	2.842050e-3
GO:0002678	positive regulation of chronic inflammatory response	2.874276e-3
GO:0030953	astral microtubule organization	2.877569e-3
GO:0070874	negative regulation of glycogen metabolic process	2.997766e-3
GO:0033683	nucleotide-excision repair, DNA incision	2.997766e-3
GO:0034447	very-low-density lipoprotein particle clearance	3.077069e-3
GO:0014053	negative regulation of gamma-aminobutyric acid secretion	3.143908e-3
GO:0060428	lung epithelium development	3.166809e-3
GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	3.282959e-3
GO:0021644	vagus nerve morphogenesis	3.387369e-3
GO:0043461	proton-transporting ATP synthase complex assembly	3.392669e-3
GO:0019348	dolichol metabolic process	3.392669e-3
GO:0060351	cartilage development involved in endochondral bone morphogenesis	3.405545e-3
GO:0060576	intestinal epithelial cell development	3.456690e-3
GO:0051103	DNA ligation involved in DNA repair	3.456690e-3
GO:0002676	regulation of chronic inflammatory response	3.499820e-3
GO:0034393	positive regulation of smooth muscle cell apoptosis	3.544813e-3
GO:0090304	nucleic acid metabolic process	3.645748e-3
GO:0031572	G2/M transition DNA damage checkpoint	3.676483e-3
GO:0007181	transforming growth factor beta receptor complex assembly	3.689890e-3
GO:0060872	semicircular canal development	3.693500e-3
GO:0003420	regulation of growth plate cartilage chondrocyte proliferation	3.718281e-3
GO:0002689	negative regulation of leukocyte chemotaxis	3.720375e-3
GO:0015788	UDP-N-acetylglucosamine transport	3.803271e-3
GO:0007140	male meiosis	3.803488e-3
GO:0090398	cellular senescence	3.815684e-3
GO:0060282	positive regulation of oocyte development	3.825235e-3
GO:0055119	relaxation of cardiac muscle	3.933204e-3
GO:0007253	cytoplasmic sequestering of NF-kappaB	3.997508e-3
GO:0007063	regulation of sister chromatid cohesion	3.997508e-3
GO:0009225	nucleotide-sugar metabolic process	4.026949e-3
GO:0021681	cerebellar granular layer development	4.089446e-3
GO:0006335	DNA replication-dependent nucleosome assembly	4.100243e-3
GO:0000183	chromatin silencing at rDNA	4.179965e-3
GO:0060087	relaxation of vascular smooth muscle	4.225123e-3
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	4.248259e-3
GO:0061003	positive regulation of dendritic spine morphogenesis	4.248259e-3
GO:0051790	short-chain fatty acid biosynthetic process	4.322274e-3
GO:0006974	response to DNA damage stimulus	4.399804e-3
GO:0018095	protein polyglutamylation	4.418298e-3
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	4.464678e-3
GO:0071313	cellular response to caffeine	4.464678e-3
GO:0010983	positive regulation of high-density lipoprotein particle clearance	4.464678e-3
GO:0035545	determination of left/right asymmetry in nervous system	4.464678e-3
GO:0021612	facial nerve structural organization	4.523010e-3
GO:0090136	epithelial cell-cell adhesion	4.553361e-3
GO:0070384	Harderian gland development	4.683849e-3
GO:0034498	early endosome to Golgi transport	4.683849e-3
GO:0031914	negative regulation of synaptic plasticity	4.683849e-3
GO:0072331	signal transduction by p53 class mediator	4.700916e-3
GO:0032897	negative regulation of viral transcription	4.749976e-3
GO:0060479	lung cell differentiation	4.751956e-3
GO:0050883	musculoskeletal movement, spinal reflex action	4.916176e-3
GO:0032938	negative regulation of translation in response to oxidative stress	4.916176e-3
GO:0043171	peptide catabolic process	4.958345e-3
GO:0015884	folic acid transport	4.958345e-3
GO:0021528	commissural neuron differentiation in spinal cord	4.962325e-3
GO:0070159	mitochondrial threonyl-tRNA aminoacylation	4.962325e-3
GO:0006051	N-acetylmannosamine metabolic process	4.962325e-3
GO:0021545	cranial nerve development	5.012697e-3
GO:0018410	C-terminal protein amino acid modification	5.085850e-3
GO:0007612	learning	5.096670e-3
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	5.142651e-3
GO:0007207	activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway	5.312024e-3
GO:0030828	positive regulation of cGMP biosynthetic process	5.312024e-3
GO:0051534	negative regulation of NFAT protein import into nucleus	5.505111e-3
GO:0070562	regulation of vitamin D receptor signaling pathway	5.517328e-3
GO:0021570	rhombomere 4 development	5.517328e-3
GO:0044260	cellular macromolecule metabolic process	5.603251e-3
GO:0006548	histidine catabolic process	5.624337e-3
GO:0009059	macromolecule biosynthetic process	5.654026e-3
GO:0051647	nucleus localization	5.656707e-3
GO:0014037	Schwann cell differentiation	5.722292e-3
GO:0014013	regulation of gliogenesis	5.723296e-3
GO:0007020	microtubule nucleation	5.727779e-3
GO:0000959	mitochondrial RNA metabolic process	5.727779e-3
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	5.761478e-3
GO:0070127	tRNA aminoacylation for mitochondrial protein translation	5.772478e-3
GO:0060575	intestinal epithelial cell differentiation	5.783830e-3
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	5.808334e-3
GO:0071585	detoxification of cadmium ion	5.840069e-3
GO:0072668	tubulin complex biogenesis	5.848614e-3
GO:0042772	DNA damage response, signal transduction resulting in transcription	5.956817e-3
GO:0031365	N-terminal protein amino acid modification	5.972818e-3
GO:0055118	negative regulation of cardiac muscle contraction	6.174943e-3
GO:0048706	embryonic skeletal system development	6.179845e-3
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	6.246013e-3
GO:0045719	negative regulation of glycogen biosynthetic process	6.277282e-3
GO:0018027	peptidyl-lysine dimethylation	6.303838e-3
GO:0016571	histone methylation	6.365720e-3
GO:0000075	cell cycle checkpoint	6.460044e-3
GO:0008033	tRNA processing	6.460984e-3
GO:0060045	positive regulation of cardiac muscle cell proliferation	6.480297e-3
GO:0002369	T cell cytokine production	6.510659e-3
GO:0001963	synaptic transmission, dopaminergic	6.555881e-3
GO:0071816	tail-anchored membrane protein insertion into ER membrane	6.833424e-3
GO:0010815	bradykinin catabolic process	6.833424e-3
GO:0045687	positive regulation of glial cell differentiation	6.842329e-3
GO:0048714	positive regulation of oligodendrocyte differentiation	6.952662e-3
GO:0009650	UV protection	7.069248e-3
GO:0071934	thiamine transmembrane transport	7.159067e-3
GO:0009159	deoxyribonucleoside monophosphate catabolic process	7.159067e-3
GO:0035445	borate transmembrane transport	7.159067e-3
GO:0009401	phosphoenolpyruvate-dependent sugar phosphotransferase system	7.159067e-3
GO:0016598	protein arginylation	7.159067e-3
GO:0033233	regulation of protein sumoylation	7.166808e-3
GO:0018105	peptidyl-serine phosphorylation	7.167941e-3
GO:0000965	mitochondrial RNA 3'-end processing	7.217471e-3
GO:0000962	positive regulation of mitochondrial RNA catabolic process	7.217471e-3
GO:0000958	mitochondrial mRNA catabolic process	7.217471e-3
GO:0046358	butyrate biosynthetic process	7.281477e-3
GO:0060580	ventral spinal cord interneuron fate determination	7.281477e-3
GO:0003327	type B pancreatic cell fate commitment	7.281477e-3
GO:0071156	regulation of cell cycle arrest	7.349508e-3
GO:0051488	activation of anaphase-promoting complex activity	7.442697e-3
GO:0006449	regulation of translational termination	7.450039e-3
GO:0017004	cytochrome complex assembly	7.555361e-3
GO:0002367	cytokine production involved in immune response	7.724431e-3
GO:0055009	atrial cardiac muscle tissue morphogenesis	7.728295e-3
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	7.803288e-3
GO:0009451	RNA modification	7.817443e-3
GO:0051584	regulation of dopamine uptake	7.861652e-3
GO:0021520	spinal cord motor neuron cell fate specification	7.863997e-3
GO:0048715	negative regulation of oligodendrocyte differentiation	7.930340e-3
GO:0032020	ISG15-protein conjugation	7.992885e-3
GO:0014052	regulation of gamma-aminobutyric acid secretion	7.992885e-3
GO:0007538	primary sex determination	8.094003e-3
GO:0061072	iris morphogenesis	8.163653e-3
GO:0060596	mammary placode formation	8.185352e-3
GO:0009147	pyrimidine nucleoside triphosphate metabolic process	8.263687e-3
GO:0060998	regulation of dendritic spine development	8.428319e-3
GO:0016486	peptide hormone processing	8.488818e-3
GO:0042228	interleukin-8 biosynthetic process	8.513521e-3
GO:0035621	ER to Golgi ceramide transport	8.513521e-3
GO:0043316	cytotoxic T cell degranulation	8.609588e-3
GO:0001830	trophectodermal cell fate commitment	8.609588e-3
GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	8.614396e-3
GO:0035019	somatic stem cell maintenance	8.648268e-3
GO:0046364	monosaccharide biosynthetic process	8.673294e-3
GO:0015872	dopamine transport	8.712943e-3
GO:0072109	glomerular mesangium development	8.743948e-3
GO:0006659	phosphatidylserine biosynthetic process	8.743948e-3
GO:0072110	glomerular mesangial cell proliferation	8.792856e-3
GO:0046349	amino sugar biosynthetic process	8.792856e-3
GO:0034198	cellular response to amino acid starvation	9.066486e-3
GO:0006826	iron ion transport	9.108553e-3
GO:0031860	telomeric 3' overhang formation	9.173873e-3
GO:0043456	regulation of pentose-phosphate shunt	9.173873e-3
GO:0016078	tRNA catabolic process	9.173873e-3
GO:0001682	tRNA 5'-leader removal	9.173873e-3
GO:0006002	fructose 6-phosphate metabolic process	9.326610e-3
GO:0035025	positive regulation of Rho protein signal transduction	9.378578e-3
GO:0048562	embryonic organ morphogenesis	9.414130e-3
GO:0043441	acetoacetic acid biosynthetic process	9.450104e-3
GO:0070846	Hsp90 deacetylation	9.525683e-3
GO:2000252	negative regulation of feeding behavior	9.525683e-3
GO:0090042	tubulin deacetylation	9.525683e-3
GO:0006272	leading strand elongation	9.525683e-3
GO:0016095	polyprenol catabolic process	9.525683e-3
GO:0018916	nitrobenzene metabolic process	9.525683e-3
GO:0030071	regulation of mitotic metaphase/anaphase transition	9.630690e-3
GO:0014014	negative regulation of gliogenesis	9.734245e-3
GO:0048073	regulation of eye pigmentation	9.839599e-3
GO:0009440	cyanate catabolic process	9.909469e-3
GO:0009051	pentose-phosphate shunt, oxidative branch	9.909469e-3
GO:0045814	negative regulation of gene expression, epigenetic	9.947696e-3
GO:0003407	neural retina development	1.012908e-2
GO:0070375	BMK cascade	1.033317e-2
GO:0006344	maintenance of chromatin silencing	1.033317e-2
GO:0055014	atrial cardiac muscle cell development	1.033317e-2
GO:0022027	interkinetic nuclear migration	1.036092e-2
GO:0021546	rhombomere development	1.055372e-2
GO:0033861	negative regulation of NAD(P)H oxidase activity	1.089057e-2
GO:0021903	rostrocaudal neural tube patterning	1.098943e-2
GO:0016048	detection of temperature stimulus	1.117066e-2
GO:0072393	microtubule anchoring at microtubule organizing center	1.142843e-2
GO:0016584	nucleosome positioning	1.142843e-2
GO:0006269	DNA replication, synthesis of RNA primer	1.188818e-2
GO:0006261	DNA-dependent DNA replication	1.190562e-2
GO:0043585	nose morphogenesis	1.194976e-2
GO:0060976	coronary vasculature development	1.221903e-2
GO:0090342	regulation of cell aging	1.224726e-2
GO:0003360	brainstem development	1.225338e-2
GO:0022601	menstrual cycle phase	1.231427e-2
GO:0060349	bone morphogenesis	1.236731e-2
GO:0044027	hypermethylation of CpG island	1.242013e-2
GO:0060152	microtubule-based peroxisome localization	1.242924e-2
GO:0070873	regulation of glycogen metabolic process	1.258519e-2
GO:0030330	DNA damage response, signal transduction by p53 class mediator	1.258610e-2
GO:0045175	basal protein localization	1.283609e-2
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	1.284221e-2
GO:0035417	negative regulation of mitotic prometaphase	1.288920e-2
GO:0090234	regulation of kinetochore assembly	1.295005e-2
GO:0090169	regulation of spindle assembly	1.295005e-2
GO:0060839	endothelial cell fate commitment	1.321874e-2
GO:0034501	protein localization to kinetochore	1.336710e-2
GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process	1.336710e-2
GO:2000772	regulation of cellular senescence	1.350976e-2
GO:0032205	negative regulation of telomere maintenance	1.354900e-2
GO:0021522	spinal cord motor neuron differentiation	1.355258e-2
GO:0031627	telomeric loop formation	1.357214e-2
GO:0060304	regulation of phosphatidylinositol dephosphorylation	1.357214e-2
GO:0031119	tRNA pseudouridine synthesis	1.357214e-2
GO:0030042	actin filament depolymerization	1.357214e-2
GO:0042274	ribosomal small subunit biogenesis	1.362140e-2
GO:0001553	luteinization	1.374567e-2
GO:0045168	cell-cell signaling involved in cell fate commitment	1.378342e-2
GO:0040030	regulation of molecular function, epigenetic	1.386616e-2
GO:2000251	positive regulation of actin cytoskeleton reorganization	1.386616e-2
GO:0006828	manganese ion transport	1.414549e-2
GO:0050872	white fat cell differentiation	1.425554e-2
GO:0031570	DNA integrity checkpoint	1.431839e-2
GO:0010801	negative regulation of peptidyl-threonine phosphorylation	1.467370e-2
GO:0042136	neurotransmitter biosynthetic process	1.468783e-2
GO:0018205	peptidyl-lysine modification	1.474798e-2
GO:0051972	regulation of telomerase activity	1.499489e-2
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.515124e-2
GO:0050775	positive regulation of dendrite morphogenesis	1.527237e-2
GO:0042254	ribosome biogenesis	1.532753e-2
GO:0055021	regulation of cardiac muscle tissue growth	1.535825e-2
GO:0009651	response to salt stress	1.546052e-2
GO:0006413	translational initiation	1.548273e-2
GO:0003310	pancreatic A cell differentiation	1.554475e-2
GO:0072061	inner medullary collecting duct development	1.562448e-2
GO:0072060	outer medullary collecting duct development	1.562448e-2
GO:0000492	box C/D snoRNP assembly	1.562448e-2
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	1.562448e-2
GO:0043653	mitochondrial fragmentation involved in apoptosis	1.567290e-2
GO:0000422	mitochondrion degradation	1.567290e-2
GO:0090219	negative regulation of lipid kinase activity	1.585169e-2
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	1.588758e-2
GO:0015827	tryptophan transport	1.588758e-2
GO:0051973	positive regulation of telomerase activity	1.605713e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0031167	rRNA methylation	3.661943e-13
GO:0000154	rRNA modification	1.950983e-11
GO:0022402	cell cycle process	3.733648e-9
GO:0006396	RNA processing	1.114421e-8
GO:0016072	rRNA metabolic process	1.460524e-8
GO:0042254	ribosome biogenesis	2.154605e-8
GO:0006364	rRNA processing	7.512648e-8
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	2.192692e-7
GO:0022403	cell cycle phase	4.350337e-7
GO:0050685	positive regulation of mRNA processing	7.934968e-7
GO:0050668	positive regulation of homocysteine metabolic process	8.050108e-7
GO:0045963	negative regulation of dopamine metabolic process	8.050108e-7
GO:0071843	cellular component biogenesis at cellular level	1.306779e-6
GO:0022613	ribonucleoprotein complex biogenesis	1.469729e-6
GO:0030902	hindbrain development	1.484355e-6
GO:0019255	glucose 1-phosphate metabolic process	1.936321e-6
GO:0019047	provirus integration	1.967026e-6
GO:0007049	cell cycle	6.174563e-6
GO:0000917	barrier septum formation	6.501464e-6
GO:0032922	circadian regulation of gene expression	6.662115e-6
GO:0000239	pachytene	7.061628e-6
GO:0000279	M phase	1.154355e-5
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	1.192954e-5
GO:0015761	mannose transport	1.362925e-5
GO:0031442	positive regulation of mRNA 3'-end processing	1.539904e-5
GO:0035282	segmentation	2.013668e-5
GO:0040029	regulation of gene expression, epigenetic	2.231253e-5
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	2.250940e-5
GO:0061014	positive regulation of mRNA catabolic process	2.295242e-5
GO:0006657	CDP-choline pathway	3.110970e-5
GO:0034446	substrate adhesion-dependent cell spreading	3.157415e-5
GO:0032446	protein modification by small protein conjugation	4.009260e-5
GO:0034470	ncRNA processing	4.444451e-5
GO:0016567	protein ubiquitination	4.483084e-5
GO:0016331	morphogenesis of embryonic epithelium	4.991794e-5
GO:0021549	cerebellum development	5.291327e-5
GO:0090224	regulation of spindle organization	5.687580e-5
GO:0051176	positive regulation of sulfur metabolic process	6.007567e-5
GO:0061053	somite development	6.838208e-5
GO:0042147	retrograde transport, endosome to Golgi	7.372936e-5
GO:0006306	DNA methylation	7.824205e-5
GO:0009138	pyrimidine nucleoside diphosphate metabolic process	7.856320e-5
GO:0007099	centriole replication	7.856320e-5
GO:0070165	positive regulation of adiponectin secretion	8.399503e-5
GO:0045362	positive regulation of interleukin-1 biosynthetic process	8.399503e-5
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	8.399503e-5
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	8.399503e-5
GO:0032707	negative regulation of interleukin-23 production	8.399503e-5
GO:0033031	positive regulation of neutrophil apoptosis	8.399503e-5
GO:0033617	mitochondrial respiratory chain complex IV assembly	8.399503e-5
GO:0051586	positive regulation of dopamine uptake	8.466149e-5
GO:0061013	regulation of mRNA catabolic process	8.494301e-5
GO:0010870	positive regulation of receptor biosynthetic process	1.040454e-4
GO:0061386	closure of optic fissure	1.069829e-4
GO:0035332	positive regulation of hippo signaling cascade	1.069829e-4
GO:0035148	tube formation	1.234254e-4
GO:0048704	embryonic skeletal system morphogenesis	1.256242e-4
GO:0001841	neural tube formation	1.368940e-4
GO:0072298	regulation of metanephric glomerulus development	1.383045e-4
GO:0001510	RNA methylation	1.429574e-4
GO:0032259	methylation	1.454355e-4
GO:0001555	oocyte growth	1.458731e-4
GO:0006261	DNA-dependent DNA replication	1.550924e-4
GO:0006139	nucleobase-containing compound metabolic process	1.567049e-4
GO:0051225	spindle assembly	1.647325e-4
GO:0090304	nucleic acid metabolic process	1.700409e-4
GO:0031440	regulation of mRNA 3'-end processing	1.706016e-4
GO:0045749	negative regulation of S phase of mitotic cell cycle	1.758944e-4
GO:0001838	embryonic epithelial tube formation	1.765151e-4
GO:0022037	metencephalon development	1.849580e-4
GO:0090286	cytoskeletal anchoring at nuclear membrane	1.920600e-4
GO:0001756	somitogenesis	1.985356e-4
GO:0000726	non-recombinational repair	2.080747e-4
GO:0043414	macromolecule methylation	2.109238e-4
GO:0060022	hard palate development	2.111993e-4
GO:0009952	anterior/posterior pattern specification	2.177835e-4
GO:0048706	embryonic skeletal system development	2.233043e-4
GO:0045930	negative regulation of mitotic cell cycle	2.239902e-4
GO:0032418	lysosome localization	2.281525e-4
GO:0034660	ncRNA metabolic process	2.431991e-4
GO:0072527	pyrimidine-containing compound metabolic process	2.518803e-4
GO:0090192	regulation of glomerulus development	2.662706e-4
GO:0032790	ribosome disassembly	2.718188e-4
GO:0018242	protein O-linked glycosylation via serine	2.942083e-4
GO:0018243	protein O-linked glycosylation via threonine	2.942083e-4
GO:0045666	positive regulation of neuron differentiation	2.954538e-4
GO:0003002	regionalization	3.000390e-4
GO:0072175	epithelial tube formation	3.072082e-4
GO:0006493	protein O-linked glycosylation	3.160008e-4
GO:0048705	skeletal system morphogenesis	3.174013e-4
GO:0007128	meiotic prophase I	3.200397e-4
GO:0060023	soft palate development	3.206593e-4
GO:2000678	negative regulation of transcription regulatory region DNA binding	3.206593e-4
GO:0051926	negative regulation of calcium ion transport	3.220664e-4
GO:0038007	netrin-activated signaling pathway	3.380494e-4
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	3.380494e-4
GO:0016340	calcium-dependent cell-matrix adhesion	3.448123e-4
GO:0000237	leptotene	3.661119e-4
GO:0006233	dTDP biosynthetic process	3.671890e-4
GO:0007346	regulation of mitotic cell cycle	3.713796e-4
GO:0042637	catagen	3.748060e-4
GO:0060012	synaptic transmission, glycinergic	3.777792e-4
GO:0051594	detection of glucose	3.833603e-4
GO:0043576	regulation of respiratory gaseous exchange	4.121939e-4
GO:0045764	positive regulation of cellular amino acid metabolic process	4.360914e-4
GO:0061298	retina vasculature development in camera-type eye	4.399264e-4
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	5.058557e-4
GO:0001839	neural plate morphogenesis	5.412579e-4
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	5.412579e-4
GO:0060262	negative regulation of N-terminal protein palmitoylation	5.488381e-4
GO:0001840	neural plate development	5.611959e-4
GO:0021915	neural tube development	5.689231e-4
GO:0006011	UDP-glucose metabolic process	5.959846e-4
GO:0071480	cellular response to gamma radiation	6.720399e-4
GO:0051298	centrosome duplication	6.909889e-4
GO:0043117	positive regulation of vascular permeability	6.957375e-4
GO:0050779	RNA destabilization	7.063858e-4
GO:0042420	dopamine catabolic process	7.063858e-4
GO:0042346	positive regulation of NF-kappaB import into nucleus	7.278896e-4
GO:0046605	regulation of centrosome cycle	7.402615e-4
GO:0000278	mitotic cell cycle	7.543268e-4
GO:0006713	glucocorticoid catabolic process	7.622184e-4
GO:0090316	positive regulation of intracellular protein transport	8.144112e-4
GO:0060389	pathway-restricted SMAD protein phosphorylation	8.425765e-4
GO:0010468	regulation of gene expression	8.684237e-4
GO:0046824	positive regulation of nucleocytoplasmic transport	9.034662e-4
GO:0072215	regulation of metanephros development	9.156599e-4
GO:0072300	positive regulation of metanephric glomerulus development	9.325558e-4
GO:2000648	positive regulation of stem cell proliferation	9.560206e-4
GO:0022007	convergent extension involved in neural plate elongation	9.696784e-4
GO:0018202	peptidyl-histidine modification	9.757156e-4
GO:0000255	allantoin metabolic process	9.904214e-4
GO:0051301	cell division	1.006147e-3
GO:0060562	epithelial tube morphogenesis	1.025281e-3
GO:0006303	double-strand break repair via nonhomologous end joining	1.027555e-3
GO:0032388	positive regulation of intracellular transport	1.062029e-3
GO:0051252	regulation of RNA metabolic process	1.067900e-3
GO:0090179	planar cell polarity pathway involved in neural tube closure	1.101286e-3
GO:0060174	limb bud formation	1.135011e-3
GO:0060364	frontal suture morphogenesis	1.175852e-3
GO:0048295	positive regulation of isotype switching to IgE isotypes	1.213783e-3
GO:0007098	centrosome cycle	1.221925e-3
GO:0008380	RNA splicing	1.224285e-3
GO:2001022	positive regulation of response to DNA damage stimulus	1.225056e-3
GO:0050684	regulation of mRNA processing	1.243666e-3
GO:2000112	regulation of cellular macromolecule biosynthetic process	1.244399e-3
GO:0016458	gene silencing	1.282345e-3
GO:0000910	cytokinesis	1.295075e-3
GO:2000602	regulation of interphase of mitotic cell cycle	1.313879e-3
GO:0070507	regulation of microtubule cytoskeleton organization	1.313879e-3
GO:0007059	chromosome segregation	1.319892e-3
GO:0002011	morphogenesis of an epithelial sheet	1.326709e-3
GO:0051321	meiotic cell cycle	1.376023e-3
GO:0007023	post-chaperonin tubulin folding pathway	1.433202e-3
GO:0042360	vitamin E metabolic process	1.433202e-3
GO:0042473	outer ear morphogenesis	1.478316e-3
GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	1.505629e-3
GO:0007140	male meiosis	1.528366e-3
GO:2000976	regulation of transcription from RNA polymerase II promoter involved in detection of glucose	1.539128e-3
GO:2000971	negative regulation of detection of glucose	1.539128e-3
GO:0000433	negative regulation of transcription from RNA polymerase II promoter by glucose	1.539128e-3
GO:0007052	mitotic spindle organization	1.582983e-3
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway	1.671352e-3
GO:0060563	neuroepithelial cell differentiation	1.692622e-3
GO:0060236	regulation of mitotic spindle organization	1.734954e-3
GO:0043932	ossification involved in bone remodeling	1.734954e-3
GO:0016070	RNA metabolic process	1.742802e-3
GO:0035330	regulation of hippo signaling cascade	1.754411e-3
GO:0007067	mitosis	1.758588e-3
GO:0014009	glial cell proliferation	1.786827e-3
GO:0051726	regulation of cell cycle	1.823994e-3
GO:0051496	positive regulation of stress fiber assembly	1.877036e-3
GO:0016071	mRNA metabolic process	1.894975e-3
GO:0046068	cGMP metabolic process	1.917944e-3
GO:0001832	blastocyst growth	1.945461e-3
GO:0006352	transcription initiation, DNA-dependent	1.979165e-3
GO:0090292	nuclear matrix anchoring at nuclear membrane	1.986202e-3
GO:0042996	regulation of Golgi to plasma membrane protein transport	1.986202e-3
GO:0060600	dichotomous subdivision of an epithelial terminal unit	2.050784e-3
GO:0002087	regulation of respiratory gaseous exchange by neurological system process	2.101686e-3
GO:0007090	regulation of S phase of mitotic cell cycle	2.121549e-3
GO:0032288	myelin assembly	2.220049e-3
GO:0043060	meiotic metaphase I plate congression	2.329945e-3
GO:0040023	establishment of nucleus localization	2.351725e-3
GO:0006397	mRNA processing	2.361347e-3
GO:0090307	spindle assembly involved in mitosis	2.377652e-3
GO:0090193	positive regulation of glomerulus development	2.407053e-3
GO:0070535	histone H2A K63-linked ubiquitination	2.408210e-3
GO:0071218	cellular response to misfolded protein	2.486074e-3
GO:0021998	neural plate mediolateral regionalization	2.488625e-3
GO:0048352	paraxial mesoderm structural organization	2.488625e-3
GO:0008208	C21-steroid hormone catabolic process	2.488625e-3
GO:0048477	oogenesis	2.490324e-3
GO:0070562	regulation of vitamin D receptor signaling pathway	2.498139e-3
GO:0010025	wax biosynthetic process	2.498139e-3
GO:0034764	positive regulation of transmembrane transport	2.612852e-3
GO:0006268	DNA unwinding involved in replication	2.632910e-3
GO:0000087	M phase of mitotic cell cycle	2.674598e-3
GO:0045454	cell redox homeostasis	2.708378e-3
GO:0007051	spindle organization	2.729832e-3
GO:0045786	negative regulation of cell cycle	2.768776e-3
GO:0046039	GTP metabolic process	2.833046e-3
GO:0051310	metaphase plate congression	2.855617e-3
GO:0007131	reciprocal meiotic recombination	2.880820e-3
GO:0042307	positive regulation of protein import into nucleus	2.914521e-3
GO:0048599	oocyte development	2.941288e-3
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	2.951180e-3
GO:0043488	regulation of mRNA stability	3.029286e-3
GO:0035194	posttranscriptional gene silencing by RNA	3.042469e-3
GO:0042053	regulation of dopamine metabolic process	3.096876e-3
GO:0051382	kinetochore assembly	3.098375e-3
GO:0042823	pyridoxal phosphate biosynthetic process	3.098375e-3
GO:0001880	Mullerian duct regression	3.113738e-3
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	3.129654e-3
GO:0050928	negative regulation of positive chemotaxis	3.129654e-3
GO:0070846	Hsp90 deacetylation	3.129654e-3
GO:0090042	tubulin deacetylation	3.129654e-3
GO:0032543	mitochondrial translation	3.129654e-3
GO:0000379	tRNA-type intron splice site recognition and cleavage	3.129654e-3
GO:0019428	allantoin biosynthetic process	3.129654e-3
GO:0019858	cytosine metabolic process	3.129654e-3
GO:0010556	regulation of macromolecule biosynthetic process	3.158203e-3
GO:0060606	tube closure	3.168331e-3
GO:0009186	deoxyribonucleoside diphosphate metabolic process	3.194546e-3
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	3.313199e-3
GO:0006904	vesicle docking involved in exocytosis	3.313395e-3
GO:0048665	neuron fate specification	3.331422e-3
GO:0033084	regulation of immature T cell proliferation in thymus	3.383996e-3
GO:0045647	negative regulation of erythrocyte differentiation	3.400928e-3
GO:0032289	central nervous system myelin formation	3.411939e-3
GO:0002009	morphogenesis of an epithelium	3.448056e-3
GO:0010564	regulation of cell cycle process	3.481776e-3
GO:0032571	response to vitamin K	3.508146e-3
GO:0060425	lung morphogenesis	3.602638e-3
GO:0035195	gene silencing by miRNA	3.638161e-3
GO:0007141	male meiosis I	3.664103e-3
GO:0042424	catecholamine catabolic process	3.683894e-3
GO:0006116	NADH oxidation	3.683894e-3
GO:0042069	regulation of catecholamine metabolic process	3.760095e-3
GO:0001843	neural tube closure	3.905774e-3
GO:0006654	phosphatidic acid biosynthetic process	3.907311e-3
GO:0006355	regulation of transcription, DNA-dependent	3.913669e-3
GO:0043046	DNA methylation involved in gamete generation	3.924012e-3
GO:0033261	regulation of S phase	3.930240e-3
GO:0043009	chordate embryonic development	3.993760e-3
GO:0019219	regulation of nucleobase-containing compound metabolic process	4.031562e-3
GO:0048630	skeletal muscle tissue growth	4.044282e-3
GO:0010659	cardiac muscle cell apoptosis	4.052972e-3
GO:0002541	activation of plasma proteins involved in acute inflammatory response	4.052972e-3
GO:0009817	defense response to fungus, incompatible interaction	4.052972e-3
GO:0055118	negative regulation of cardiac muscle contraction	4.185637e-3
GO:0006259	DNA metabolic process	4.206751e-3
GO:0048285	organelle fission	4.289841e-3
GO:0044065	regulation of respiratory system process	4.308961e-3
GO:0061304	retinal blood vessel morphogenesis	4.348816e-3
GO:0008608	attachment of spindle microtubules to kinetochore	4.348816e-3
GO:2000677	regulation of transcription regulatory region DNA binding	4.558878e-3
GO:0043487	regulation of RNA stability	4.605956e-3
GO:0006220	pyrimidine nucleotide metabolic process	4.638270e-3
GO:0042993	positive regulation of transcription factor import into nucleus	4.823843e-3
GO:0070936	protein K48-linked ubiquitination	4.833820e-3
GO:0000209	protein polyubiquitination	4.928490e-3
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	5.060477e-3
GO:0046827	positive regulation of protein export from nucleus	5.132853e-3
GO:0043148	mitotic spindle stabilization	5.146734e-3
GO:0007389	pattern specification process	5.152754e-3
GO:0070918	production of small RNA involved in gene silencing by RNA	5.156108e-3
GO:0051171	regulation of nitrogen compound metabolic process	5.250731e-3
GO:0071173	spindle assembly checkpoint	5.271314e-3
GO:0010608	posttranscriptional regulation of gene expression	5.306910e-3
GO:0006730	one-carbon metabolic process	5.332233e-3
GO:0003357	noradrenergic neuron differentiation	5.424195e-3
GO:0034968	histone lysine methylation	5.513437e-3
GO:0006651	diacylglycerol biosynthetic process	5.627999e-3
GO:0030262	apoptotic nuclear change	5.656280e-3
GO:0046164	alcohol catabolic process	5.663539e-3
GO:0009081	branched chain family amino acid metabolic process	5.752189e-3
GO:0051058	negative regulation of small GTPase mediated signal transduction	5.762573e-3
GO:2000344	positive regulation of acrosome reaction	5.818692e-3
GO:0070192	chromosome organization involved in meiosis	5.935161e-3
GO:0019320	hexose catabolic process	5.959020e-3
GO:0045143	homologous chromosome segregation	6.011328e-3
GO:0009994	oocyte differentiation	6.057043e-3
GO:0070163	regulation of adiponectin secretion	6.155250e-3
GO:0007196	inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway	6.155250e-3
GO:0010389	regulation of G2/M transition of mitotic cell cycle	6.171295e-3
GO:0090305	nucleic acid phosphodiester bond hydrolysis	6.254165e-3
GO:0072368	regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter	6.261230e-3
GO:0072362	regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter	6.261230e-3
GO:0006931	substrate-dependent cell migration, cell attachment to substrate	6.261230e-3
GO:0046580	negative regulation of Ras protein signal transduction	6.299394e-3
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	6.345232e-3
GO:0042667	auditory receptor cell fate specification	6.345232e-3
GO:0014895	smooth muscle hypertrophy	6.345232e-3
GO:0045609	positive regulation of auditory receptor cell differentiation	6.345232e-3
GO:0060975	cardioblast migration to the midline involved in heart field formation	6.345232e-3
GO:0003106	negative regulation of glomerular filtration by angiotensin	6.345232e-3
GO:0009438	methylglyoxal metabolic process	6.345232e-3
GO:0003210	cardiac atrium formation	6.345232e-3
GO:0003259	cardioblast anterior-lateral migration	6.345232e-3
GO:0003236	sinus venosus morphogenesis	6.345232e-3
GO:0007050	cell cycle arrest	6.427692e-3
GO:0060441	epithelial tube branching involved in lung morphogenesis	6.448931e-3
GO:0044260	cellular macromolecule metabolic process	6.488268e-3
GO:0002268	follicular dendritic cell differentiation	6.488636e-3
GO:0031577	spindle checkpoint	6.528231e-3
GO:0010467	gene expression	6.597097e-3
GO:0048278	vesicle docking	6.667013e-3
GO:0033083	regulation of immature T cell proliferation	6.692635e-3
GO:0000956	nuclear-transcribed mRNA catabolic process	6.742439e-3
GO:0035567	non-canonical Wnt receptor signaling pathway	6.747859e-3
GO:0051568	histone H3-K4 methylation	6.805584e-3
GO:0016197	endosome transport	6.951615e-3
GO:0006308	DNA catabolic process	7.007404e-3
GO:0045814	negative regulation of gene expression, epigenetic	7.017958e-3
GO:0006098	pentose-phosphate shunt	7.064511e-3
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	7.188166e-3
GO:0016075	rRNA catabolic process	7.188166e-3
GO:0014020	primary neural tube formation	7.205374e-3
GO:0007126	meiosis	7.244605e-3
GO:0048663	neuron fate commitment	7.320300e-3
GO:0014067	negative regulation of phosphatidylinositol 3-kinase cascade	7.494484e-3
GO:0006184	GTP catabolic process	7.764164e-3
GO:0070634	transepithelial ammonium transport	7.790155e-3
GO:0072124	regulation of glomerular mesangial cell proliferation	7.839173e-3
GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	7.891432e-3
GO:0035196	production of miRNAs involved in gene silencing by miRNA	7.907491e-3
GO:0046069	cGMP catabolic process	7.922117e-3
GO:0016180	snRNA processing	7.922117e-3
GO:0070534	protein K63-linked ubiquitination	7.979897e-3
GO:0051656	establishment of organelle localization	7.987086e-3
GO:0072488	ammonium transmembrane transport	8.103883e-3
GO:0060376	positive regulation of mast cell differentiation	8.329761e-3
GO:0008611	ether lipid biosynthetic process	8.329761e-3
GO:0002537	nitric oxide production involved in inflammatory response	8.329761e-3
GO:0010225	response to UV-C	8.460511e-3
GO:0006260	DNA replication	8.465528e-3
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	8.553446e-3
GO:0051313	attachment of spindle microtubules to chromosome	8.603153e-3
GO:0048387	negative regulation of retinoic acid receptor signaling pathway	8.634695e-3
GO:0010002	cardioblast differentiation	8.845614e-3
GO:0051303	establishment of chromosome localization	8.931236e-3
GO:0051169	nuclear transport	8.997445e-3
GO:0031047	gene silencing by RNA	9.054794e-3
GO:0006086	acetyl-CoA biosynthetic process from pyruvate	9.068671e-3
GO:0090234	regulation of kinetochore assembly	9.098365e-3
GO:0090169	regulation of spindle assembly	9.098365e-3
GO:0001705	ectoderm formation	9.098365e-3
GO:0002030	inhibitory G-protein coupled receptor phosphorylation	9.098365e-3
GO:0007060	male meiosis chromosome segregation	9.098365e-3
GO:0032229	negative regulation of synaptic transmission, GABAergic	9.184412e-3
GO:0006450	regulation of translational fidelity	9.400437e-3
GO:0048026	positive regulation of nuclear mRNA splicing, via spliceosome	9.429530e-3
GO:0006346	methylation-dependent chromatin silencing	9.429530e-3
GO:0009792	embryo development ending in birth or egg hatching	9.451138e-3
GO:0043001	Golgi to plasma membrane protein transport	9.960257e-3
GO:0045014	negative regulation of transcription by glucose	1.001921e-2
GO:0006515	misfolded or incompletely synthesized protein catabolic process	1.001921e-2
GO:0032914	positive regulation of transforming growth factor beta1 production	1.008102e-2
GO:0006921	cellular component disassembly involved in apoptosis	1.011850e-2
GO:0045880	positive regulation of smoothened signaling pathway	1.017691e-2
GO:0045084	positive regulation of interleukin-12 biosynthetic process	1.031250e-2
GO:0034587	piRNA metabolic process	1.055067e-2
GO:0032508	DNA duplex unwinding	1.060413e-2
GO:0032981	mitochondrial respiratory chain complex I assembly	1.060860e-2
GO:0042761	very long-chain fatty acid biosynthetic process	1.071266e-2
GO:0060466	activation of meiosis involved in egg activation	1.076443e-2
GO:0009452	RNA capping	1.076443e-2
GO:0050774	negative regulation of dendrite morphogenesis	1.076443e-2
GO:2000001	regulation of DNA damage checkpoint	1.076786e-2
GO:0070368	positive regulation of hepatocyte differentiation	1.076786e-2
GO:0031268	pseudopodium organization	1.076786e-2
GO:0014805	smooth muscle adaptation	1.076786e-2
GO:0043271	negative regulation of ion transport	1.080366e-2
GO:0071479	cellular response to ionizing radiation	1.085212e-2
GO:0006401	RNA catabolic process	1.095554e-2
GO:0042345	regulation of NF-kappaB import into nucleus	1.109736e-2
GO:0032727	positive regulation of interferon-alpha production	1.110147e-2
GO:0002513	tolerance induction to self antigen	1.110147e-2
GO:0055119	relaxation of cardiac muscle	1.131033e-2
GO:0006729	tetrahydrobiopterin biosynthetic process	1.131033e-2
GO:0007127	meiosis I	1.147189e-2
GO:0002089	lens morphogenesis in camera-type eye	1.147189e-2
GO:0006913	nucleocytoplasmic transport	1.157392e-2
GO:0032845	negative regulation of homeostatic process	1.159731e-2
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	1.171952e-2
GO:0060437	lung growth	1.174000e-2
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	1.174000e-2
GO:0033683	nucleotide-excision repair, DNA incision	1.205789e-2
GO:0060028	convergent extension involved in axis elongation	1.205789e-2
GO:0033132	negative regulation of glucokinase activity	1.205789e-2
GO:0019405	alditol catabolic process	1.205789e-2
GO:0016073	snRNA metabolic process	1.207634e-2
GO:0006646	phosphatidylethanolamine biosynthetic process	1.226024e-2
GO:0072513	positive regulation of secondary heart field cardioblast proliferation	1.226943e-2
GO:0006417	regulation of translation	1.234666e-2
GO:0045132	meiotic chromosome segregation	1.260746e-2
GO:0035721	intraflagellar retrograde transport	1.269762e-2
GO:0017187	peptidyl-glutamic acid carboxylation	1.269762e-2
GO:0061015	snRNA import into nucleus	1.269762e-2
GO:0009443	pyridoxal 5'-phosphate salvage	1.269762e-2
GO:0006683	galactosylceramide catabolic process	1.269762e-2
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	1.271061e-2
GO:0018120	peptidyl-arginine ADP-ribosylation	1.271061e-2
GO:0000075	cell cycle checkpoint	1.271329e-2
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	1.282244e-2
GO:0051383	kinetochore organization	1.282244e-2
GO:0046501	protoporphyrinogen IX metabolic process	1.282244e-2
GO:0051584	regulation of dopamine uptake	1.299329e-2
GO:0034508	centromere complex assembly	1.299329e-2
GO:0090212	negative regulation of establishment of blood-brain barrier	1.301420e-2
GO:2000781	positive regulation of double-strand break repair	1.301420e-2
GO:0015969	guanosine tetraphosphate metabolic process	1.301420e-2
GO:2000299	negative regulation of Rho-dependent protein serine/threonine kinase activity	1.301420e-2
GO:0090168	Golgi reassembly	1.301420e-2
GO:0001546	preantral ovarian follicle growth	1.301420e-2
GO:0014853	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction	1.301420e-2
GO:0007100	mitotic centrosome separation	1.301420e-2
GO:0009236	cobalamin biosynthetic process	1.301420e-2
GO:0007506	gonadal mesoderm development	1.301420e-2
GO:0001710	mesodermal cell fate commitment	1.301878e-2
GO:0035520	monoubiquitinated protein deubiquitination	1.317081e-2
GO:0032525	somite rostral/caudal axis specification	1.351671e-2
GO:0042474	middle ear morphogenesis	1.353746e-2
GO:0031345	negative regulation of cell projection organization	1.394140e-2
GO:0072110	glomerular mesangial cell proliferation	1.395486e-2
GO:0048755	branching morphogenesis of a nerve	1.395486e-2
GO:0070734	histone H3-K27 methylation	1.395486e-2
GO:0015879	carnitine transport	1.395486e-2
GO:0045116	protein neddylation	1.395486e-2
GO:0032392	DNA geometric change	1.396925e-2
GO:0007431	salivary gland development	1.401307e-2
GO:0033157	regulation of intracellular protein transport	1.406763e-2
GO:0006573	valine metabolic process	1.418399e-2
GO:0046544	development of secondary male sexual characteristics	1.418449e-2
GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly	1.418449e-2
GO:0006007	glucose catabolic process	1.435091e-2
GO:0030307	positive regulation of cell growth	1.449907e-2
GO:0000070	mitotic sister chromatid segregation	1.461810e-2
GO:0002053	positive regulation of mesenchymal cell proliferation	1.542488e-2
GO:0006304	DNA modification	1.565442e-2
GO:0043653	mitochondrial fragmentation involved in apoptosis	1.567859e-2
GO:0035441	cell migration involved in vasculogenesis	1.567859e-2
GO:0034453	microtubule anchoring	1.570448e-2
GO:0032020	ISG15-protein conjugation	1.582361e-2
GO:0051386	regulation of nerve growth factor receptor signaling pathway	1.594218e-2
GO:0051320	S phase	1.594218e-2
GO:0042119	neutrophil activation	1.594218e-2
GO:0002072	optic cup morphogenesis involved in camera-type eye development	1.594856e-2
GO:0009133	nucleoside diphosphate biosynthetic process	1.617220e-2
GO:0033239	negative regulation of cellular amine metabolic process	1.629253e-2
GO:0033233	regulation of protein sumoylation	1.633955e-2
GO:0046365	monosaccharide catabolic process	1.640499e-2
GO:0045066	regulatory T cell differentiation	1.642858e-2
GO:0015696	ammonium transport	1.642858e-2
GO:0072091	regulation of stem cell proliferation	1.643754e-2
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	1.643754e-2
GO:0048385	regulation of retinoic acid receptor signaling pathway	1.656857e-2
GO:0048536	spleen development	1.679080e-2
GO:0021695	cerebellar cortex development	1.692097e-2
GO:0033092	positive regulation of immature T cell proliferation in thymus	1.704433e-2
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	1.707332e-2
GO:0045759	negative regulation of action potential	1.707332e-2
GO:0000729	DNA double-strand break processing	1.707332e-2
GO:0000414	regulation of histone H3-K36 methylation	1.707332e-2
GO:0032507	maintenance of protein location in cell	1.711377e-2
GO:0030497	fatty acid elongation	1.720411e-2
GO:0006997	nucleus organization	1.721826e-2
GO:0045064	T-helper 2 cell differentiation	1.727901e-2
GO:0071585	detoxification of cadmium ion	1.727901e-2
GO:0032456	endocytic recycling	1.732816e-2
GO:0043114	regulation of vascular permeability	1.784791e-2
GO:0006269	DNA replication, synthesis of RNA primer	1.786397e-2
GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	1.791679e-2
GO:0072361	regulation of glycolysis by regulation of transcription from RNA polymerase II promoter	1.791679e-2
GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway	1.814723e-2
GO:0032608	interferon-beta production	1.814723e-2
GO:0046092	deoxycytidine metabolic process	1.814723e-2
GO:0000080	G1 phase of mitotic cell cycle	1.839330e-2
GO:2000778	positive regulation of interleukin-6 secretion	1.848237e-2
GO:0061301	cerebellum vasculature morphogenesis	1.848237e-2
GO:0030421	defecation	1.848237e-2
GO:0051466	positive regulation of corticotropin-releasing hormone secretion	1.848237e-2
GO:0071174	mitotic cell cycle spindle checkpoint	1.850381e-2
GO:0051318	G1 phase	1.854423e-2
GO:0034661	ncRNA catabolic process	1.873947e-2
GO:0009451	RNA modification	1.914799e-2
GO:0007030	Golgi organization	1.918185e-2
GO:0014032	neural crest cell development	1.921453e-2
GO:0010457	centriole-centriole cohesion	1.947706e-2
GO:0007129	synapsis	1.949225e-2
GO:0090183	regulation of kidney development	1.953250e-2
GO:0051642	centrosome localization	1.986361e-2
GO:0050680	negative regulation of epithelial cell proliferation	1.999296e-2
GO:0033578	protein glycosylation in Golgi	2.003643e-2
GO:0070102	interleukin-6-mediated signaling pathway	2.003888e-2
GO:0032825	positive regulation of natural killer cell differentiation	2.003888e-2
GO:0017145	stem cell division	2.043119e-2
GO:0022406	membrane docking	2.043851e-2
GO:0048484	enteric nervous system development	2.051244e-2